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Conserved domains on  [gi|2231661233|ref|NP_001392463|]
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uncharacterized protein LOC102724250 isoform 1 [Homo sapiens]

Protein Classification

NBPF family protein( domain architecture ID 10535968)

neuroblastoma breakpoint family (NBPF) protein is a DUF1220 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1271-1338 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1271 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1338
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1516-1583 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1516 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1583
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1026-1093 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1026 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1093
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1617-1678 2.02e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.93  E-value: 2.02e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1617 DQNPPCPRLSGVLMEVEEPEILQDSLDRCYSTPSMFFELPDSFQHYRSVFYSFEEQHISFAL 1678
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
951-1018 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233  951 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1018
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1196-1263 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1196 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1263
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1441-1508 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1441 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1508
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
876-943 7.17e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 7.17e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233  876 DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 943
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1127-1188 8.71e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 8.71e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1127 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 1188
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1372-1433 8.71e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 8.71e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1372 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 1433
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
719-782 4.52e-13

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 65.52  E-value: 4.52e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2231661233  719 EVAEKVQKSSAP---RDMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782
Cdd:pfam06758    2 EEEEEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
180-240 8.74e-11

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 58.97  E-value: 8.74e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2231661233  180 EKVLESSAP---REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 240
Cdd:pfam06758    5 EEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
451-511 8.74e-11

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 58.97  E-value: 8.74e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2231661233  451 EKVLESSAP---REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511
Cdd:pfam06758    5 EEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
813-867 3.03e-06

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 46.26  E-value: 3.03e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2231661233  813 PVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMA 867
Cdd:pfam06758   13 PRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSA 67
PTZ00121 super family cl31754
MAEBL; Provisional
29-473 5.68e-04

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   29 AEKKQQFRNLKE-KCFVTQLAGFLANRQKKYKYEECKDVIKFmlrneRQFKEEKLAEQLKQAEELRQYKVLVHSQE--RE 105
Cdd:PTZ00121  1242 AKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADEL-----KKAEEKKKADEAKKAEEKKKADEAKKKAEeaKK 1316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  106 LTQLREKLREGRDASRSLNQHLQALLTLDEPDKSQGQDLQEQL------AEGCRLAQQLFQKLSPENDEDEDEDVQVEEA 179
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAeaaeekAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  180 EKVLESSAPR--EVQKAEESKVPEDSLEECAitcsnshgpcDSNQPHKNINITFEEDKVNSALvvdrESSHDECQDAVNI 257
Cdd:PTZ00121  1397 KKKAEEDKKKadELKKAAAAKKKADEAKKKA----------EEKKKADEAKKKAEEAKKADEA----KKKAEEAKKAEEA 1462
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  258 LPVPGPTSSATNVSmvvsagplssEKAEMNilEINEKLHPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECKDL 337
Cdd:PTZ00121  1463 KKKAEEAKKADEAK----------KKAEEA--KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  338 IKSMLRNE-------RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLR--EKLREGRDASRSLNQHLQALLTPDKPD 408
Cdd:PTZ00121  1531 EEAKKADEakkaeekKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKKAEEARIEEVMKLYEEEKKMKAE 1610
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2231661233  409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDvqvEEAEKVLESSAPREVQKAEESKVPED 473
Cdd:PTZ00121  1611 EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK---KKAEELKKAEEENKIKAAEEAKKAEE 1672
 
Name Accession Description Interval E-value
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1271-1338 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1271 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1338
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1516-1583 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1516 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1583
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1026-1093 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1026 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1093
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1617-1678 2.02e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.93  E-value: 2.02e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1617 DQNPPCPRLSGVLMEVEEPEILQDSLDRCYSTPSMFFELPDSFQHYRSVFYSFEEQHISFAL 1678
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
951-1018 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233  951 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1018
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1196-1263 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1196 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1263
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1441-1508 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1441 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1508
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
876-943 7.17e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 7.17e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233  876 DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 943
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1127-1188 8.71e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 8.71e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1127 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 1188
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1372-1433 8.71e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 8.71e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1372 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 1433
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
719-782 4.52e-13

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 65.52  E-value: 4.52e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2231661233  719 EVAEKVQKSSAP---RDMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782
Cdd:pfam06758    2 EEEEEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
180-240 8.74e-11

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 58.97  E-value: 8.74e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2231661233  180 EKVLESSAP---REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 240
Cdd:pfam06758    5 EEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
451-511 8.74e-11

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 58.97  E-value: 8.74e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2231661233  451 EKVLESSAP---REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511
Cdd:pfam06758    5 EEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
813-867 3.03e-06

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 46.26  E-value: 3.03e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2231661233  813 PVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMA 867
Cdd:pfam06758   13 PRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSA 67
PTZ00121 PTZ00121
MAEBL; Provisional
29-473 5.68e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   29 AEKKQQFRNLKE-KCFVTQLAGFLANRQKKYKYEECKDVIKFmlrneRQFKEEKLAEQLKQAEELRQYKVLVHSQE--RE 105
Cdd:PTZ00121  1242 AKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADEL-----KKAEEKKKADEAKKAEEKKKADEAKKKAEeaKK 1316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  106 LTQLREKLREGRDASRSLNQHLQALLTLDEPDKSQGQDLQEQL------AEGCRLAQQLFQKLSPENDEDEDEDVQVEEA 179
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAeaaeekAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  180 EKVLESSAPR--EVQKAEESKVPEDSLEECAitcsnshgpcDSNQPHKNINITFEEDKVNSALvvdrESSHDECQDAVNI 257
Cdd:PTZ00121  1397 KKKAEEDKKKadELKKAAAAKKKADEAKKKA----------EEKKKADEAKKKAEEAKKADEA----KKKAEEAKKAEEA 1462
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  258 LPVPGPTSSATNVSmvvsagplssEKAEMNilEINEKLHPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECKDL 337
Cdd:PTZ00121  1463 KKKAEEAKKADEAK----------KKAEEA--KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  338 IKSMLRNE-------RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLR--EKLREGRDASRSLNQHLQALLTPDKPD 408
Cdd:PTZ00121  1531 EEAKKADEakkaeekKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKKAEEARIEEVMKLYEEEKKMKAE 1610
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2231661233  409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDvqvEEAEKVLESSAPREVQKAEESKVPED 473
Cdd:PTZ00121  1611 EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK---KKAEELKKAEEENKIKAAEEAKKAEE 1672
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
22-692 6.39e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 6.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   22 EKLRPQlAEKKQQFRNLKEKCFVTQLAgFLANR--QKKYKYEECKDVIKfmlRNERQFKEEKLAEQLKQA--EELRQYKV 97
Cdd:TIGR02168  203 KSLERQ-AEKAERYKELKAELRELELA-LLVLRleELREELEELQEELK---EAEEELEELTAELQELEEklEELRLEVS 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   98 LVHSQERELTQ-----------LREKLREGRDASRSLNQHLQALLTLDEPDKSQGQDLQEQLAEgcrlAQQLFQKLSPEN 166
Cdd:TIGR02168  278 ELEEEIEELQKelyalaneisrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE----LEEKLEELKEEL 353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  167 DEdededvqveeaekvLESSAPREVQKAEESKVPEDSLEECAITCSNshgpcDSNQPHKNINITFEEDKVNSALVVDRES 246
Cdd:TIGR02168  354 ES--------------LEAELEELEAELEELESRLEELEEQLETLRS-----KVAQLELQIASLNNEIERLEARLERLED 414
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  247 SHDECQDAVNILpvpgpTSSATNVSMVVSAGPLSSEKAEMNIL-EINEKLHPQLAEKKQQFRNLKEKcfVTQLAGFLANQ 325
Cdd:TIGR02168  415 RRERLQQEIEEL-----LKKLEEAELKELQAELEELEEELEELqEELERLEEALEELREELEEAEQA--LDAAERELAQL 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  326 QNKykyeecKDLIKSMLRNERQFKEEkLAEQLKQAEELRQYKVLVhsqeRELTQLREKLREGRDAsrSLNQHLQALLTPD 405
Cdd:TIGR02168  488 QAR------LDSLERLQENLEGFSEG-VKALLKNQSGLSGILGVL----SELISVDEGYEAAIEA--ALGGRLQAVVVEN 554
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  406 KPDKSQGQDLQEQLAEGcrLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNS 485
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELG--RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  486 HGPCDSNQPHKNINI--------------TFEEDKVNSAlVVDRESSHDECQDAVNILpvpgpTSSATNVSMVVSAgpls 551
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpggviTGGSAKTNSS-ILERRREIEELEEKIEEL-----EEKIAELEKALAE---- 702
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  552 SEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCF-----VTQLAGFLANQQ-NKYKYEECKDLIKSMLRNERQFKEEKLA 625
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLArleaeVEQLEERIAQLSkELTELEAEIEELEERLEEAEEELAEAEA 782
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2231661233  626 EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAE 692
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849
 
Name Accession Description Interval E-value
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1271-1338 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1271 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1338
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1516-1583 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1516 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1583
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1026-1093 8.34e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.09  E-value: 8.34e-19
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1026 DQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1093
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1617-1678 2.02e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.93  E-value: 2.02e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1617 DQNPPCPRLSGVLMEVEEPEILQDSLDRCYSTPSMFFELPDSFQHYRSVFYSFEEQHISFAL 1678
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
951-1018 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233  951 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1018
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1196-1263 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1196 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1263
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1441-1508 2.25e-18

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 80.54  E-value: 2.25e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233 1441 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVHSLEEQYLGLAL 1508
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
876-943 7.17e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 7.17e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2231661233  876 DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 943
Cdd:pfam06758    1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1127-1188 8.71e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 8.71e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1127 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 1188
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
1372-1433 8.71e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 8.71e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2231661233 1372 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWAL 1433
Cdd:pfam06758    7 DQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
719-782 4.52e-13

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 65.52  E-value: 4.52e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2231661233  719 EVAEKVQKSSAP---RDMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782
Cdd:pfam06758    2 EEEEEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
180-240 8.74e-11

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 58.97  E-value: 8.74e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2231661233  180 EKVLESSAP---REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 240
Cdd:pfam06758    5 EEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
451-511 8.74e-11

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 58.97  E-value: 8.74e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2231661233  451 EKVLESSAP---REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511
Cdd:pfam06758    5 EEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
813-867 3.03e-06

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 46.26  E-value: 3.03e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2231661233  813 PVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMA 867
Cdd:pfam06758   13 PRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSA 67
PTZ00121 PTZ00121
MAEBL; Provisional
29-473 5.68e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   29 AEKKQQFRNLKE-KCFVTQLAGFLANRQKKYKYEECKDVIKFmlrneRQFKEEKLAEQLKQAEELRQYKVLVHSQE--RE 105
Cdd:PTZ00121  1242 AKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADEL-----KKAEEKKKADEAKKAEEKKKADEAKKKAEeaKK 1316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  106 LTQLREKLREGRDASRSLNQHLQALLTLDEPDKSQGQDLQEQL------AEGCRLAQQLFQKLSPENDEDEDEDVQVEEA 179
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAeaaeekAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  180 EKVLESSAPR--EVQKAEESKVPEDSLEECAitcsnshgpcDSNQPHKNINITFEEDKVNSALvvdrESSHDECQDAVNI 257
Cdd:PTZ00121  1397 KKKAEEDKKKadELKKAAAAKKKADEAKKKA----------EEKKKADEAKKKAEEAKKADEA----KKKAEEAKKAEEA 1462
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  258 LPVPGPTSSATNVSmvvsagplssEKAEMNilEINEKLHPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECKDL 337
Cdd:PTZ00121  1463 KKKAEEAKKADEAK----------KKAEEA--KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  338 IKSMLRNE-------RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLR--EKLREGRDASRSLNQHLQALLTPDKPD 408
Cdd:PTZ00121  1531 EEAKKADEakkaeekKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKKAEEARIEEVMKLYEEEKKMKAE 1610
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2231661233  409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDvqvEEAEKVLESSAPREVQKAEESKVPED 473
Cdd:PTZ00121  1611 EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK---KKAEELKKAEEENKIKAAEEAKKAEE 1672
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
22-692 6.39e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 6.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   22 EKLRPQlAEKKQQFRNLKEKCFVTQLAgFLANR--QKKYKYEECKDVIKfmlRNERQFKEEKLAEQLKQA--EELRQYKV 97
Cdd:TIGR02168  203 KSLERQ-AEKAERYKELKAELRELELA-LLVLRleELREELEELQEELK---EAEEELEELTAELQELEEklEELRLEVS 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   98 LVHSQERELTQ-----------LREKLREGRDASRSLNQHLQALLTLDEPDKSQGQDLQEQLAEgcrlAQQLFQKLSPEN 166
Cdd:TIGR02168  278 ELEEEIEELQKelyalaneisrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE----LEEKLEELKEEL 353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  167 DEdededvqveeaekvLESSAPREVQKAEESKVPEDSLEECAITCSNshgpcDSNQPHKNINITFEEDKVNSALVVDRES 246
Cdd:TIGR02168  354 ES--------------LEAELEELEAELEELESRLEELEEQLETLRS-----KVAQLELQIASLNNEIERLEARLERLED 414
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  247 SHDECQDAVNILpvpgpTSSATNVSMVVSAGPLSSEKAEMNIL-EINEKLHPQLAEKKQQFRNLKEKcfVTQLAGFLANQ 325
Cdd:TIGR02168  415 RRERLQQEIEEL-----LKKLEEAELKELQAELEELEEELEELqEELERLEEALEELREELEEAEQA--LDAAERELAQL 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  326 QNKykyeecKDLIKSMLRNERQFKEEkLAEQLKQAEELRQYKVLVhsqeRELTQLREKLREGRDAsrSLNQHLQALLTPD 405
Cdd:TIGR02168  488 QAR------LDSLERLQENLEGFSEG-VKALLKNQSGLSGILGVL----SELISVDEGYEAAIEA--ALGGRLQAVVVEN 554
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  406 KPDKSQGQDLQEQLAEGcrLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNS 485
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELG--RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  486 HGPCDSNQPHKNINI--------------TFEEDKVNSAlVVDRESSHDECQDAVNILpvpgpTSSATNVSMVVSAgpls 551
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpggviTGGSAKTNSS-ILERRREIEELEEKIEEL-----EEKIAELEKALAE---- 702
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  552 SEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCF-----VTQLAGFLANQQ-NKYKYEECKDLIKSMLRNERQFKEEKLA 625
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLArleaeVEQLEERIAQLSkELTELEAEIEELEERLEEAEEELAEAEA 782
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2231661233  626 EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAE 692
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849
PTZ00121 PTZ00121
MAEBL; Provisional
52-779 1.03e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233   52 ANRQKKYKYEECKDVIKFMLRNERQFKE-EKLAEQLKQAEELRQykvlvhsqERELTQLREKLREGRDASRSLNQHLQAL 130
Cdd:PTZ00121  1092 ATEEAFGKAEEAKKTETGKAEEARKAEEaKKKAEDARKAEEARK--------AEDARKAEEARKAEDAKRVEIARKAEDA 1163
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  131 LTLDEPDKSQGQDLQEQL--AEGCRLAQQLFQKLSPENDEDEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLE 205
Cdd:PTZ00121  1164 RKAEEARKAEDAKKAEAArkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaeAVKKAEEAKKDAEEAK 1243
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  206 ECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNIlpvpgptSSATNVSMVVSAGPLSSEKAE 285
Cdd:PTZ00121  1244 KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEA-------KKAEEKKKADEAKKKAEEAKK 1316
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  286 MnileinEKLHPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECKDLIKSMLRNERQFKEEKL--------AEQL 357
Cdd:PTZ00121  1317 A------DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKkadaakkkAEEK 1390
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  358 KQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQHLVQKlspen 437
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK----- 1465
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  438 deDEDEDVQVEEAEKVLESSAPREV-QKAEESKVPEDSLEECAitcsnshgpcDSNQPHKNINITFEEDKVNSALVVDRE 516
Cdd:PTZ00121  1466 --AEEAKKADEAKKKAEEAKKADEAkKKAEEAKKKADEAKKAA----------EAKKKADEAKKAEEAKKADEAKKAEEA 1533
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  517 SSHDECQDAvnilpvpgptssatnvsmvvsagplsSEKAEMNILEMNEKLRPQLAEKK-QQFRNLKEKCFVTQLAGFLAN 595
Cdd:PTZ00121  1534 KKADEAKKA--------------------------EEKKKADELKKAEELKKAEEKKKaEEAKKAEEDKNMALRKAEEAK 1587
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  596 QQNKYKYEECKDLIKSMLRNE----RQFKEEKL-AEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQ 670
Cdd:PTZ00121  1588 KAEEARIEEVMKLYEEEKKMKaeeaKKAEEAKIkAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA 1667
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2231661233  671 allTPDEPDKSQGQDLQEQLAEGCRLAQHL---------VQKLSPENDNDDDEDVQVEVAEKVQ-------KSSAPRDMQ 734
Cdd:PTZ00121  1668 ---KKAEEDKKKAEEAKKAEEDEKKAAEALkkeaeeakkAEELKKKEAEEKKKAEELKKAEEENkikaeeaKKEAEEDKK 1744
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 2231661233  735 KAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 779
Cdd:PTZ00121  1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED 1789
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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