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Conserved domains on  [gi|2239796793|ref|NP_001393387|]
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vicilin-like antimicrobial peptides 2-1 precursor [Macadamia integrifolia]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
cupin_7S_vicilin-like_N cd02244
7S vicilin seed storage globulin, N-terminal cupin domain; This family contains the N-terminal ...
 264-439 1.17e-90

7S vicilin seed storage globulin, N-terminal cupin domain; This family contains the N-terminal domains of plant 7S seed storage proteins such as vicilin, and includes beta-conglycinin, phaseolin, canavalin, conglutin-beta, a chromatin protein in Pisum sativum called P54, and a sucrose binding protein in soybean called SBP. These 7S globulins also include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2, and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The vicilin peptides formed by trypsin or chymotrypsin digestion exhibit antihypertensive effects. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


:

Pssm-ID: 380371  Cd Length: 178  Bit Score: 279.01  E-value: 1.17e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 264 RFRTEEGHISVLENFYGRSKLLRALKNYRLVLLEANPNAFVLPTHLDADAILLVIGGRGALKMIHRDNRESYNLECGDVI 343
Cdd:cd02244     1 VVRTEAGEIRVLERFDGRSRLLRGIENYRLAFITMEPNTLFLPHHLDADMVFYVHTGRGTITWVDEDKRESYNLERGDVY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 344 RIPAGTTFYLINRDNNERLHIAKFLQTIS--TPGQYKEFFPAGGQNPEPYLSTFSKEILEAALNTQTERLRGVLGQQREG 421
Cdd:cd02244    81 RIPAGSTFYLVNTDENEKLRIIALFDPVNslTPGPFQSFFGAGGQNPESLLSGFSKEILEAAFNVSEEELERLLSQQKPG 160

                         170
                  ....*....|....*...
gi 2239796793 422 VIIRASQEQIRELTRDDS 439
Cdd:cd02244   161 PIVKASEEQIRALSRHAS 178
cupin_7S_vicilin-like_C cd02245
7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal ...
 464-636 1.54e-78

7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal domain of plant 7S seed storage protein such as vicilin and includes beta-conglycinin, phaseolin, canavalin, conglutin-beta, a chromatin protein in Pisum sativum called P54, and a sucrose binding protein in soybean called SBP. These 7S globulins also include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2 and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The vicilin peptides formed by trypsin or chymotrypsin digestion exhibit antihypertensive effects. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


:

Pssm-ID: 380372  Cd Length: 166  Bit Score: 247.04  E-value: 1.54e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 464 PLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLSgrhggrGGGKRH 543
Cdd:cd02245     1 PDFSNQYGWLYEADPEDYKQLKDLDVGVSFVNITQGSMMAPHYNSRATEIAVVVEGEGYVEMVCPHLS------SQSQQG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 544 EEEEEVHYEQVRARLSKREAIVVLAGHPVVFVSSGNENLLLFAFGINAQNNHENFLAGRErNVLQQIEPQAMELAFAASR 623
Cdd:cd02245    75 EEEGSGEYQKVRARLSEGDVFVVPAGHPVAQVASSNENLEFVGFGINAQNNERQFLAGKN-NVLRQLDREAKELAFNVPA 153

                         170
                  ....*....|...
gi 2239796793 624 KEVEELFNSQDES 636
Cdd:cd02245   154 EEVEEVLNAQDES 166
Vicilin_N pfam04702
Vicilin N terminal region; This region is found in plant seed storage proteins, N-terminal to ...
 72-245 2.55e-16

Vicilin N terminal region; This region is found in plant seed storage proteins, N-terminal to the Cupin domain (pfam00190). In Macadamia integrifolia, this region is processed into peptides of approximately 50 amino acids containing a C-X-X-X-C-(10-12)X-C-X-X-X-C motif. These peptides exhibit antimicrobial activity in vitro.


:

Pssm-ID: 252749 [Multi-domain]  Cd Length: 147  Bit Score: 76.29  E-value: 2.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  72 SKYDNQEDPQTECQQCQRRCRQQESDPRQQQYCQRRCKEICEEEEEYNRQR--DPQQQYEQCQKRCQRRetEPRHMQICQ 149
Cdd:pfam04702   1 PGRRNEDDPQQRYEQCQRRCEQETRGQREQQQCERRCKEQYKEEQQQQRQReeDPQRRYEQCQQRCQQH--EPRHRPTCQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 150 QRCERRYEKEKRKqqkryeeqqredeekyeermkegdnkrdpQQREYEDCRRHCEQQE--PRLQYQCQRRCQEQQRQHGR 227
Cdd:pfam04702  79 QRCERRYEKEQQQ-----------------------------QQRQYQECQQRCQQQEqrPRRQQQCQRECREQYQEHGR 129

                         170
                  ....*....|....*...
gi 2239796793 228 GGDLMNPQRGGSGRYEEG 245
Cdd:pfam04702 130 GEGENINQEGEEERSEEG 147
 
Name Accession Description Interval E-value
cupin_7S_vicilin-like_N cd02244
7S vicilin seed storage globulin, N-terminal cupin domain; This family contains the N-terminal ...
 264-439 1.17e-90

7S vicilin seed storage globulin, N-terminal cupin domain; This family contains the N-terminal domains of plant 7S seed storage proteins such as vicilin, and includes beta-conglycinin, phaseolin, canavalin, conglutin-beta, a chromatin protein in Pisum sativum called P54, and a sucrose binding protein in soybean called SBP. These 7S globulins also include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2, and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The vicilin peptides formed by trypsin or chymotrypsin digestion exhibit antihypertensive effects. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380371  Cd Length: 178  Bit Score: 279.01  E-value: 1.17e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 264 RFRTEEGHISVLENFYGRSKLLRALKNYRLVLLEANPNAFVLPTHLDADAILLVIGGRGALKMIHRDNRESYNLECGDVI 343
Cdd:cd02244     1 VVRTEAGEIRVLERFDGRSRLLRGIENYRLAFITMEPNTLFLPHHLDADMVFYVHTGRGTITWVDEDKRESYNLERGDVY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 344 RIPAGTTFYLINRDNNERLHIAKFLQTIS--TPGQYKEFFPAGGQNPEPYLSTFSKEILEAALNTQTERLRGVLGQQREG 421
Cdd:cd02244    81 RIPAGSTFYLVNTDENEKLRIIALFDPVNslTPGPFQSFFGAGGQNPESLLSGFSKEILEAAFNVSEEELERLLSQQKPG 160

                         170
                  ....*....|....*...
gi 2239796793 422 VIIRASQEQIRELTRDDS 439
Cdd:cd02244   161 PIVKASEEQIRALSRHAS 178
cupin_7S_vicilin-like_C cd02245
7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal ...
 464-636 1.54e-78

7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal domain of plant 7S seed storage protein such as vicilin and includes beta-conglycinin, phaseolin, canavalin, conglutin-beta, a chromatin protein in Pisum sativum called P54, and a sucrose binding protein in soybean called SBP. These 7S globulins also include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2 and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The vicilin peptides formed by trypsin or chymotrypsin digestion exhibit antihypertensive effects. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380372  Cd Length: 166  Bit Score: 247.04  E-value: 1.54e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 464 PLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLSgrhggrGGGKRH 543
Cdd:cd02245     1 PDFSNQYGWLYEADPEDYKQLKDLDVGVSFVNITQGSMMAPHYNSRATEIAVVVEGEGYVEMVCPHLS------SQSQQG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 544 EEEEEVHYEQVRARLSKREAIVVLAGHPVVFVSSGNENLLLFAFGINAQNNHENFLAGRErNVLQQIEPQAMELAFAASR 623
Cdd:cd02245    75 EEEGSGEYQKVRARLSEGDVFVVPAGHPVAQVASSNENLEFVGFGINAQNNERQFLAGKN-NVLRQLDREAKELAFNVPA 153

                         170
                  ....*....|...
gi 2239796793 624 KEVEELFNSQDES 636
Cdd:cd02245   154 EEVEEVLNAQDES 166
Cupin_1 smart00835
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 460-627 4.30e-43

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 214845 [Multi-domain]  Cd Length: 146  Bit Score: 152.05  E-value: 4.30e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  460 FNKRPLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLsgrhggrgg 539
Cdd:smart00835   1 LEPRPDFSNEGGRLREADPTNFPALNGLGISAARVNLEPGGMLPPHYHPRATELLYVVRGEGRVGVVDPNG--------- 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  540 gkrheeeeevhYEQVRARLSKREAIVVLAGHPVVFVSSGNENLLLFAFGINAqNNHENFLAGRErNVLQQIEPQAMELAF 619
Cdd:smart00835  72 -----------NKVYDARLREGDVFVVPQGHPHFQVNSGDENLEFVAFNTND-PNRRFFLAGRN-SVLRGLPPEVLAAAF 138


                   ....*...
gi 2239796793  620 AASRKEVE 627
Cdd:smart00835 139 GVSAEEVR 146
Cupin_1 pfam00190
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 457-627 2.58e-20

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 395138  Cd Length: 151  Bit Score: 87.78  E-value: 2.58e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 457 YNLFNKRPLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLSGRHGg 536
Cdd:pfam00190   1 LNLLEPGPTYNPEGGRVTTVNSKNLPGLNTLGISAARVDLAPGGMNPPHWHPNATEILYVLQGRGRVGFVVPGNGNRVF- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 537 rgggkrheeeeevhyeqvRARLSKREAIVVLAGHPVVFVSSGNENLLLF-AFGINAQNNHENFLAGreRNVLQQIEPQAM 615
Cdd:pfam00190  80 ------------------HKVLREGDVFVVPQGLPHFQYNIGDEPAVAFvAFDTNNPGNQSILAGG--FSSLPALPPEVL 139

                         170
                  ....*....|..
gi 2239796793 616 ELAFAASRKEVE 627
Cdd:pfam00190 140 AKAFQLAGEEVK 151
Vicilin_N pfam04702
Vicilin N terminal region; This region is found in plant seed storage proteins, N-terminal to ...
 72-245 2.55e-16

Vicilin N terminal region; This region is found in plant seed storage proteins, N-terminal to the Cupin domain (pfam00190). In Macadamia integrifolia, this region is processed into peptides of approximately 50 amino acids containing a C-X-X-X-C-(10-12)X-C-X-X-X-C motif. These peptides exhibit antimicrobial activity in vitro.


Pssm-ID: 252749 [Multi-domain]  Cd Length: 147  Bit Score: 76.29  E-value: 2.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  72 SKYDNQEDPQTECQQCQRRCRQQESDPRQQQYCQRRCKEICEEEEEYNRQR--DPQQQYEQCQKRCQRRetEPRHMQICQ 149
Cdd:pfam04702   1 PGRRNEDDPQQRYEQCQRRCEQETRGQREQQQCERRCKEQYKEEQQQQRQReeDPQRRYEQCQQRCQQH--EPRHRPTCQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 150 QRCERRYEKEKRKqqkryeeqqredeekyeermkegdnkrdpQQREYEDCRRHCEQQE--PRLQYQCQRRCQEQQRQHGR 227
Cdd:pfam04702  79 QRCERRYEKEQQQ-----------------------------QQRQYQECQQRCQQQEqrPRRQQQCQRECREQYQEHGR 129

                         170
                  ....*....|....*...
gi 2239796793 228 GGDLMNPQRGGSGRYEEG 245
Cdd:pfam04702 130 GEGENINQEGEEERSEEG 147
Cupin_1 smart00835
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 276-405 6.87e-14

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 214845 [Multi-domain]  Cd Length: 146  Bit Score: 69.23  E-value: 6.87e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  276 ENFYGRSKL-----LRALK--NYRLVLLEANPNAFVLP-THLDADAILLVIGGRGALKMIH-RDNRE-SYNLECGDVIRI 345
Cdd:smart00835   8 SNEGGRLREadptnFPALNglGISAARVNLEPGGMLPPhYHPRATELLYVVRGEGRVGVVDpNGNKVyDARLREGDVFVV 87

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  346 PAGTTFYLINrDNNERLHIAKFlqtiSTPGQYKEFFPAGGQNpepYLSTFSKEILEAALN 405
Cdd:smart00835  88 PQGHPHFQVN-SGDENLEFVAF----NTNDPNRRFFLAGRNS---VLRGLPPEVLAAAFG 139
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 118-211 1.78e-05

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 47.49  E-value: 1.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 118 YNRQrdpQQQY-------EQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQkryeEQQREDEEKYEERMKEGDNKRD 190
Cdd:PRK09510   64 YNRQ---QQQQksakraeEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQ----EQKKQAEEAAKQAALKQKQAEE 136

                          90       100
                  ....*....|....*....|.
gi 2239796793 191 PQQREYEDCRRHCEQQEPRLQ 211
Cdd:PRK09510  137 AAAKAAAAAKAKAEAEAKRAA 157
Cupin_1 pfam00190
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 291-405 4.21e-04

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 395138  Cd Length: 151  Bit Score: 41.17  E-value: 4.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 291 YRLVLleaNPNAFVLP-THLDADAILLVIGGRGALKMI--HRDNR-ESYNLECGDVIRIPAGTTFYLINRDNNERLHIAK 366
Cdd:pfam00190  36 ARVDL---APGGMNPPhWHPNATEILYVLQGRGRVGFVvpGNGNRvFHKVLREGDVFVVPQGLPHFQYNIGDEPAVAFVA 112

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2239796793 367 FlqtiSTPGQYKEFFPAGGQNPEPYLSTfskEILEAALN 405
Cdd:pfam00190 113 F----DTNNPGNQSILAGGFSSLPALPP---EVLAKAFQ 144
ManC COG0662
Mannose-6-phosphate isomerase, cupin superfamily [Carbohydrate transport and metabolism];
289-364 2.95e-03

Mannose-6-phosphate isomerase, cupin superfamily [Carbohydrate transport and metabolism];


Pssm-ID: 440426 [Multi-domain]  Cd Length: 114  Bit Score: 37.81  E-value: 2.95e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2239796793 289 KNYRLVLLEANPNA-FVLPTHLDADAILLVIGGRGALKMihrdNRESYNLECGDVIRIPAGTTFYLINRDnNERLHI 364
Cdd:COG0662    25 ERLSVKRITVPPGAeLSLHVHPHRDEFFYVLEGTGEVTI----GDEEVELKAGDSVYIPAGVPHRLRNPG-DEPLEL 96
 
Name Accession Description Interval E-value
cupin_7S_vicilin-like_N cd02244
7S vicilin seed storage globulin, N-terminal cupin domain; This family contains the N-terminal ...
 264-439 1.17e-90

7S vicilin seed storage globulin, N-terminal cupin domain; This family contains the N-terminal domains of plant 7S seed storage proteins such as vicilin, and includes beta-conglycinin, phaseolin, canavalin, conglutin-beta, a chromatin protein in Pisum sativum called P54, and a sucrose binding protein in soybean called SBP. These 7S globulins also include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2, and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The vicilin peptides formed by trypsin or chymotrypsin digestion exhibit antihypertensive effects. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380371  Cd Length: 178  Bit Score: 279.01  E-value: 1.17e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 264 RFRTEEGHISVLENFYGRSKLLRALKNYRLVLLEANPNAFVLPTHLDADAILLVIGGRGALKMIHRDNRESYNLECGDVI 343
Cdd:cd02244     1 VVRTEAGEIRVLERFDGRSRLLRGIENYRLAFITMEPNTLFLPHHLDADMVFYVHTGRGTITWVDEDKRESYNLERGDVY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 344 RIPAGTTFYLINRDNNERLHIAKFLQTIS--TPGQYKEFFPAGGQNPEPYLSTFSKEILEAALNTQTERLRGVLGQQREG 421
Cdd:cd02244    81 RIPAGSTFYLVNTDENEKLRIIALFDPVNslTPGPFQSFFGAGGQNPESLLSGFSKEILEAAFNVSEEELERLLSQQKPG 160

                         170
                  ....*....|....*...
gi 2239796793 422 VIIRASQEQIRELTRDDS 439
Cdd:cd02244   161 PIVKASEEQIRALSRHAS 178
cupin_7S_vicilin-like_C cd02245
7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal ...
 464-636 1.54e-78

7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal domain of plant 7S seed storage protein such as vicilin and includes beta-conglycinin, phaseolin, canavalin, conglutin-beta, a chromatin protein in Pisum sativum called P54, and a sucrose binding protein in soybean called SBP. These 7S globulins also include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2 and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The vicilin peptides formed by trypsin or chymotrypsin digestion exhibit antihypertensive effects. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380372  Cd Length: 166  Bit Score: 247.04  E-value: 1.54e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 464 PLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLSgrhggrGGGKRH 543
Cdd:cd02245     1 PDFSNQYGWLYEADPEDYKQLKDLDVGVSFVNITQGSMMAPHYNSRATEIAVVVEGEGYVEMVCPHLS------SQSQQG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 544 EEEEEVHYEQVRARLSKREAIVVLAGHPVVFVSSGNENLLLFAFGINAQNNHENFLAGRErNVLQQIEPQAMELAFAASR 623
Cdd:cd02245    75 EEEGSGEYQKVRARLSEGDVFVVPAGHPVAQVASSNENLEFVGFGINAQNNERQFLAGKN-NVLRQLDREAKELAFNVPA 153

                         170
                  ....*....|...
gi 2239796793 624 KEVEELFNSQDES 636
Cdd:cd02245   154 EEVEEVLNAQDES 166
Cupin_1 smart00835
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 460-627 4.30e-43

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 214845 [Multi-domain]  Cd Length: 146  Bit Score: 152.05  E-value: 4.30e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  460 FNKRPLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLsgrhggrgg 539
Cdd:smart00835   1 LEPRPDFSNEGGRLREADPTNFPALNGLGISAARVNLEPGGMLPPHYHPRATELLYVVRGEGRVGVVDPNG--------- 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  540 gkrheeeeevhYEQVRARLSKREAIVVLAGHPVVFVSSGNENLLLFAFGINAqNNHENFLAGRErNVLQQIEPQAMELAF 619
Cdd:smart00835  72 -----------NKVYDARLREGDVFVVPQGHPHFQVNSGDENLEFVAFNTND-PNRRFFLAGRN-SVLRGLPPEVLAAAF 138


                   ....*...
gi 2239796793  620 AASRKEVE 627
Cdd:smart00835 139 GVSAEEVR 146
Cupin_1 pfam00190
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 457-627 2.58e-20

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 395138  Cd Length: 151  Bit Score: 87.78  E-value: 2.58e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 457 YNLFNKRPLYSNKYGQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHLSGRHGg 536
Cdd:pfam00190   1 LNLLEPGPTYNPEGGRVTTVNSKNLPGLNTLGISAARVDLAPGGMNPPHWHPNATEILYVLQGRGRVGFVVPGNGNRVF- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 537 rgggkrheeeeevhyeqvRARLSKREAIVVLAGHPVVFVSSGNENLLLF-AFGINAQNNHENFLAGreRNVLQQIEPQAM 615
Cdd:pfam00190  80 ------------------HKVLREGDVFVVPQGLPHFQYNIGDEPAVAFvAFDTNNPGNQSILAGG--FSSLPALPPEVL 139

                         170
                  ....*....|..
gi 2239796793 616 ELAFAASRKEVE 627
Cdd:pfam00190 140 AKAFQLAGEEVK 151
Vicilin_N pfam04702
Vicilin N terminal region; This region is found in plant seed storage proteins, N-terminal to ...
 72-245 2.55e-16

Vicilin N terminal region; This region is found in plant seed storage proteins, N-terminal to the Cupin domain (pfam00190). In Macadamia integrifolia, this region is processed into peptides of approximately 50 amino acids containing a C-X-X-X-C-(10-12)X-C-X-X-X-C motif. These peptides exhibit antimicrobial activity in vitro.


Pssm-ID: 252749 [Multi-domain]  Cd Length: 147  Bit Score: 76.29  E-value: 2.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  72 SKYDNQEDPQTECQQCQRRCRQQESDPRQQQYCQRRCKEICEEEEEYNRQR--DPQQQYEQCQKRCQRRetEPRHMQICQ 149
Cdd:pfam04702   1 PGRRNEDDPQQRYEQCQRRCEQETRGQREQQQCERRCKEQYKEEQQQQRQReeDPQRRYEQCQQRCQQH--EPRHRPTCQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 150 QRCERRYEKEKRKqqkryeeqqredeekyeermkegdnkrdpQQREYEDCRRHCEQQE--PRLQYQCQRRCQEQQRQHGR 227
Cdd:pfam04702  79 QRCERRYEKEQQQ-----------------------------QQRQYQECQQRCQQQEqrPRRQQQCQRECREQYQEHGR 129

                         170
                  ....*....|....*...
gi 2239796793 228 GGDLMNPQRGGSGRYEEG 245
Cdd:pfam04702 130 GEGENINQEGEEERSEEG 147
Cupin_1 smart00835
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 276-405 6.87e-14

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 214845 [Multi-domain]  Cd Length: 146  Bit Score: 69.23  E-value: 6.87e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  276 ENFYGRSKL-----LRALK--NYRLVLLEANPNAFVLP-THLDADAILLVIGGRGALKMIH-RDNRE-SYNLECGDVIRI 345
Cdd:smart00835   8 SNEGGRLREadptnFPALNglGISAARVNLEPGGMLPPhYHPRATELLYVVRGEGRVGVVDpNGNKVyDARLREGDVFVV 87

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793  346 PAGTTFYLINrDNNERLHIAKFlqtiSTPGQYKEFFPAGGQNpepYLSTFSKEILEAALN 405
Cdd:smart00835  88 PQGHPHFQVN-SGDENLEFVAF----NTNDPNRRFFLAGRNS---VLRGLPPEVLAAAFG 139
cupin_11S_legumin_N cd02242
11S legumin seed storage globulin, N-terminal cupin domain; This family contains the ...
 262-428 1.27e-11

11S legumin seed storage globulin, N-terminal cupin domain; This family contains the N-terminal domains of 11S legumin seed storage proteins that supply nutrition for seed germination, such as glycinin and legumin, including many common food allergens such as the peanut major allergen Ara h 3, almond allergen Pru du 6, Pecan allergen Car i 4, hazelnut nut allergen Cor a 9, Brazil nut allergen Ber e 2, cashew allergen Ana o 2, pistachio allergen Pis v 2/5, and walnut allergen Jug n/r 4. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). They are synthesized as propeptides in the endoplasmic reticulum and transported to the secretory vesicles as a homotrimer. The propeptides are processed as they are sorted in the secretory vesicles. The homotrimer binds another homotrimer to form a homohexamer with 32-point symmetry formed by a face-to-face stacking of the two trimers. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380369  Cd Length: 209  Bit Score: 64.53  E-value: 1.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 262 STRFRTEEGHIsvlENFYGRSKLLR-----ALknyRLVLleaNPNAFVLPTHLDADAILLVIGGRGALKMI--------- 327
Cdd:cd02242    10 TRRIESEGGSY---EYWDPNNPQLQcagvaAG---RLTI---EPRGLLLPSYSNAPKLAYVLQGRGIVGVVfpgcpetfq 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 328 -----------HRDNRES-YNLECGDVIRIPAGTTFYLINrDNNERLhIAKFLQTIST-----PGQYKEFFPAGGQNPEP 390
Cdd:cd02242    81 ssqqsqgqgqrFRDQHQKvRRIRKGDVIAVPAGVVHWWYN-DGDSDL-VIVFLGDTSNnanqlDGNFRRFFLAGNPQQEQ 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2239796793 391 Y------------LSTFSKEILEAALNTQTERLRGVLGQQRE-GVIIRASQ 428
Cdd:cd02242   159 QgqgqeqsgggniFSGFSTEFLAEAFGVDEETARKLQGSQDQrGLIVKVEE 209
cupin_7S_11S_C cd20285
7S and 11S seed storage globulin, C-terminal cupin domain; This family contains the C-terminal ...
 471-600 6.42e-08

7S and 11S seed storage globulin, C-terminal cupin domain; This family contains the C-terminal cupin domains of 7S and 11S seed storage proteins. The 7S globulins include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2, and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The 11S globulins include many common food allergens such as the peanut major allergen Ara h 3, almond allergen Pru du 6, pecan allergen Car i 4, hazelnut nut allergen Cor a 9, Brazil nut allergen Ber e 2, cashew allergen Ana o 2, pistachio allergen Pis v 2/5, and walnut allergen Jug n/r 4. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380420  Cd Length: 109  Bit Score: 51.07  E-value: 6.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 471 GQAYEVKPEDYRQLQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMACPHlsgrhggrgggkrheeeeevH 550
Cdd:cd20285     1 GNVTERTSNDFPILKSLNLLASSISLEEGAMFVPHYYSKAIVILVVNEGRAHIQVVGPK--------------------G 60

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2239796793 551 YEQVRARLSKREAIVVLAGHPVVFVSSGNeNLLLFAFGINAQNNHENFLA 600
Cdd:cd20285    61 YESYDAELSKGDVFVVPAAFPVAIKSTSH-NVEFTGFGTNANNNNRNLLA 109
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 118-211 1.78e-05

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 47.49  E-value: 1.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 118 YNRQrdpQQQY-------EQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQkryeEQQREDEEKYEERMKEGDNKRD 190
Cdd:PRK09510   64 YNRQ---QQQQksakraeEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQ----EQKKQAEEAAKQAALKQKQAEE 136

                          90       100
                  ....*....|....*....|.
gi 2239796793 191 PQQREYEDCRRHCEQQEPRLQ 211
Cdd:PRK09510  137 AAAKAAAAAKAKAEAEAKRAA 157
cupin_11S_legumin_C cd02243
11S legumin seed storage globulin, C-terminal cupin domain; This family contains the ...
 484-640 2.20e-04

11S legumin seed storage globulin, C-terminal cupin domain; This family contains the C-terminal domains of 11S legumin seed storage proteins that supply nutrition for seed germination, such as glycinin and legumin, including many common food allergens such as the peanut major allergen Ara h 3, almond allergen Pru du 6, Pecan allergen Car i 4, hazelnut nut allergen Cor a 9, Brazil nut allergen Ber e 2, cashew allergen Ana o 2, pistachio allergen Pis v 2/5, and walnut allergen Jug n/r 4. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). They are synthesized as propeptides in the endoplasmic reticulum and transported to the secretory vesicles as a homotrimer. The propeptides are processed as they are sorted in the secretory vesicles. The homotrimer binds another homotrimer to form a homohexamer with 32-point symmetry formed by a face-to-face stacking of the two trimers. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380370  Cd Length: 155  Bit Score: 42.08  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 484 LQDMDVSVFIANITQGSMMGPFFNTRSTKVVVVASGEADVEMAcphlsgrhggrgggkrHEEEEEVHYEQVRA-RLskre 562
Cdd:cd02243    21 LRFVGLSAERVKLEPNAMFAPHWNANAHQVIYVTRGSGRVQVV----------------GDNGKRVLDGEVREgQL---- 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2239796793 563 aIVVLAGHPVVfVSSGNENLLLFAFgINAQNNHENFLAGReRNVLQQIEPQAMELAFAASRKEVEEL-FNSQDESIFFP 640
Cdd:cd02243    81 -LVVPQFFAVA-KIAGEEGFEWVSF-KTSDNPIFSELAGR-TSVLRALPPEVLANSYNISPEEAKQLkSNREKETVLFP 155
cupin_RmlC-like cd02208
RmlC-like cupin superfamily; This superfamily contains proteins similar to the RmlC (dTDP ...
 293-360 2.93e-04

RmlC-like cupin superfamily; This superfamily contains proteins similar to the RmlC (dTDP (deoxythymidine diphosphates)-4-dehydrorhamnose 3,5-epimerase)-like cupins. RmlC is a dTDP-sugar isomerase involved in the synthesis of L-rhamnose, a saccharide required for the virulence of some pathogenic bacteria. Cupins are a functionally diverse superfamily originally discovered based on the highly conserved motif found in germin and germin-like proteins. This conserved motif forms a beta-barrel fold found in all of the cupins, giving rise to the name cupin ('cupa' is the Latin term for small barrel). The active site of members of this superfamily is generally located at the center of a conserved barrel and usually includes a metal ion. The different functional classes in this superfamily include single domain bacterial isomerases and epimerases involved in the modification of cell wall carbohydrates, two domain bicupins such as the desiccation-tolerant seed storage globulins, and multidomain nuclear transcription factors involved in legume root nodulation.


Pssm-ID: 380338 [Multi-domain]  Cd Length: 73  Bit Score: 39.77  E-value: 2.93e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2239796793 293 LVLLEANPNAFVLP-THLDADAILLVIGGRGALKMihrDNRESYNLECGDVIRIPAGTTFYLINRDNNE 360
Cdd:cd02208     1 ISVVTLPPGTSSPPhWHPEQDEIFYVLSGEGELTL---DDGETVELKAGDIVLIPPGVPHSFVNTSDEP 66
Cupin_1 pfam00190
Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' ...
 291-405 4.21e-04

Cupin; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel). This family contains 11S and 7S plant seed storage proteins, and germins. Plant seed storage proteins provide the major nitrogen source for the developing plant.


Pssm-ID: 395138  Cd Length: 151  Bit Score: 41.17  E-value: 4.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 291 YRLVLleaNPNAFVLP-THLDADAILLVIGGRGALKMI--HRDNR-ESYNLECGDVIRIPAGTTFYLINRDNNERLHIAK 366
Cdd:pfam00190  36 ARVDL---APGGMNPPhWHPNATEILYVLQGRGRVGFVvpGNGNRvFHKVLREGDVFVVPQGLPHFQYNIGDEPAVAFVA 112

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2239796793 367 FlqtiSTPGQYKEFFPAGGQNPEPYLSTfskEILEAALN 405
Cdd:pfam00190 113 F----DTNNPGNQSILAGGFSSLPALPP---EVLAKAFQ 144
cupin_7S_vicilin-like_C cd02245
7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal ...
 276-420 2.21e-03

7S vicilin seed storage globulin, C-terminal cupin domain; This family contains C-terminal domain of plant 7S seed storage protein such as vicilin and includes beta-conglycinin, phaseolin, canavalin, conglutin-beta, a chromatin protein in Pisum sativum called P54, and a sucrose binding protein in soybean called SBP. These 7S globulins also include soybean allergen beta-conglycinin, peanut allergen conarachin (Ara h 1), walnut allergen Jug r 2 and lentil allergen Len c 1. Proteins in this family perform various functions, including a role in sucrose binding, desiccation, defense against microbes and oxidative stress. The vicilin peptides formed by trypsin or chymotrypsin digestion exhibit antihypertensive effects. These plant seed storage globulins have tandem cupin-like beta-barrel folds (referred to as a bicupin). Storage proteins are the cause of well-known allergic reactions to peanuts and cereals. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380372  Cd Length: 166  Bit Score: 39.42  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 276 ENFYGRS-----KLLRALK--NYRLVLLEANPNAFVLPtHLD--ADAILLVIGGRGALKMI-----------HRDNRESY 335
Cdd:cd02245     4 SNQYGWLyeadpEDYKQLKdlDVGVSFVNITQGSMMAP-HYNsrATEIAVVVEGEGYVEMVcphlssqsqqgEEEGSGEY 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 336 N-----LECGDVIRIPAGTTFYLINrDNNERLHIAKFlqTISTPGQYKEFFpAGGQNPepyLSTFSKEILEAALNTQTER 410
Cdd:cd02245    83 QkvrarLSEGDVFVVPAGHPVAQVA-SSNENLEFVGF--GINAQNNERQFL-AGKNNV---LRQLDREAKELAFNVPAEE 155

                         170
                  ....*....|
gi 2239796793 411 LRGVLGQQRE 420
Cdd:cd02245   156 VEEVLNAQDE 165
ManC COG0662
Mannose-6-phosphate isomerase, cupin superfamily [Carbohydrate transport and metabolism];
289-364 2.95e-03

Mannose-6-phosphate isomerase, cupin superfamily [Carbohydrate transport and metabolism];


Pssm-ID: 440426 [Multi-domain]  Cd Length: 114  Bit Score: 37.81  E-value: 2.95e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2239796793 289 KNYRLVLLEANPNA-FVLPTHLDADAILLVIGGRGALKMihrdNRESYNLECGDVIRIPAGTTFYLINRDnNERLHI 364
Cdd:COG0662    25 ERLSVKRITVPPGAeLSLHVHPHRDEFFYVLEGTGEVTI----GDEEVELKAGDSVYIPAGVPHRLRNPG-DEPLEL 96
DDRGK pfam09756
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 146-211 4.72e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 38.87  E-value: 4.72e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2239796793 146 QICQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEGDNKRDPQQREYEDCRRHCEQQEPRLQ 211
Cdd:pfam09756   2 KLGAKKRAKLELKEAKRQQREAEEEEREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQ 67
QdoI COG1917
Cupin domain protein related to quercetin dioxygenase [General function prediction only];
281-375 7.15e-03

Cupin domain protein related to quercetin dioxygenase [General function prediction only];


Pssm-ID: 441521 [Multi-domain]  Cd Length: 99  Bit Score: 36.37  E-value: 7.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2239796793 281 RSKLLRALKNYRLVLLEANPNAfVLPTHL-DADAILLVIGGRGalkmIHRDNRESYNLECGDVIRIPAGTTFYLINRDNN 359
Cdd:COG1917    13 VRVLADGEDELEVVRVTFEPGA-RTPWHShPGEELIYVLEGEG----EVEVGGEEYELKPGDVVFIPPGVPHAFRNLGDE 87

                          90
                  ....*....|....*.
gi 2239796793 360 ERLHIAkflqtISTPG 375
Cdd:COG1917    88 PAVLLV-----VFSPG 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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