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Conserved domains on  [gi|5174397|ref|NP_006048|]
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beta-1,3-galactosyltransferase 5 isoform a [Homo sapiens]

Protein Classification

Galactosyl_T domain-containing protein( domain architecture ID 10484746)

Galactosyl_T domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
71-261 3.95e-67

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


:

Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 208.33  E-value: 3.95e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397     71 AERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAE-TKE-VDQESQRHGDIIQKDFLDVYYNLTLKTMMGIEWVHRFCPQ 148
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADTDGkVADlVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397    149 AAFVMKTDSDMFINVDYLTELLLKK--NRTTRFFTGFLKLNEFPIRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVA 226
Cdd:pfam01762  81 AKYIGKIDDDVYFFPDKLLSLLDNGniDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAA 160
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 5174397    227 SQVYNVSKSVPYIKLEDVFVGLCLERLNIRLEELH 261
Cdd:pfam01762 161 EKLLKASKHRRFLQIEDVYVGILANDLGISRVNLP 195
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
71-261 3.95e-67

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 208.33  E-value: 3.95e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397     71 AERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAE-TKE-VDQESQRHGDIIQKDFLDVYYNLTLKTMMGIEWVHRFCPQ 148
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADTDGkVADlVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397    149 AAFVMKTDSDMFINVDYLTELLLKK--NRTTRFFTGFLKLNEFPIRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVA 226
Cdd:pfam01762  81 AKYIGKIDDDVYFFPDKLLSLLDNGniDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAA 160
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 5174397    227 SQVYNVSKSVPYIKLEDVFVGLCLERLNIRLEELH 261
Cdd:pfam01762 161 EKLLKASKHRRFLQIEDVYVGILANDLGISRVNLP 195
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
56-307 2.21e-32

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 126.45  E-value: 2.21e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397    56 PPFLVLLVTSSHKQLAERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAETKEVDQESQRHGDIIQKDFLDvYYNL-TLK 134
Cdd:PLN03133 384 PLDLFIGVFSTANNFKRRMAVRRTWMQYDAVRSGAVAVRFFVGLHKNQMVNEELWNEARTYGDIQLMPFVD-YYSLiTWK 462
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397   135 T----MMGIEWVhrfcpQAAFVMKTDSDMFINVDyltELLLKKNRTTR---FFTGFLKLNEFPIRQPFSKWFVSKSEYPW 207
Cdd:PLN03133 463 TlaicIFGTEVV-----SAKYVMKTDDDAFVRVD---EVLASLKRTNVshgLLYGLINSDSQPHRNPDSKWYISPEEWPE 534
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397   208 DRYPPFCSGTGYVFSGDVASQVYNVSKS--VPYIKLEDVFVGlclerlnIRLEELHSqptffpGGLRFSVCLFRRI---- 281
Cdd:PLN03133 535 ETYPPWAHGPGYVVSRDIAKEVYKRHKEgrLKMFKLEDVAMG-------IWIAEMKK------EGLEVKYENDGRIyneg 601
                        250       260       270
                 ....*....|....*....|....*....|.
gi 5174397   282 -----VACHFIKPRTLLDYWQALENSRGEDC 307
Cdd:PLN03133 602 ckdgyVVAHYQSPREMLCLWQKLQEGKRATC 632
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
71-261 3.95e-67

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 208.33  E-value: 3.95e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397     71 AERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAE-TKE-VDQESQRHGDIIQKDFLDVYYNLTLKTMMGIEWVHRFCPQ 148
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADTDGkVADlVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397    149 AAFVMKTDSDMFINVDYLTELLLKK--NRTTRFFTGFLKLNEFPIRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVA 226
Cdd:pfam01762  81 AKYIGKIDDDVYFFPDKLLSLLDNGniDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAA 160
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 5174397    227 SQVYNVSKSVPYIKLEDVFVGLCLERLNIRLEELH 261
Cdd:pfam01762 161 EKLLKASKHRRFLQIEDVYVGILANDLGISRVNLP 195
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
56-307 2.21e-32

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 126.45  E-value: 2.21e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397    56 PPFLVLLVTSSHKQLAERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAETKEVDQESQRHGDIIQKDFLDvYYNL-TLK 134
Cdd:PLN03133 384 PLDLFIGVFSTANNFKRRMAVRRTWMQYDAVRSGAVAVRFFVGLHKNQMVNEELWNEARTYGDIQLMPFVD-YYSLiTWK 462
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397   135 T----MMGIEWVhrfcpQAAFVMKTDSDMFINVDyltELLLKKNRTTR---FFTGFLKLNEFPIRQPFSKWFVSKSEYPW 207
Cdd:PLN03133 463 TlaicIFGTEVV-----SAKYVMKTDDDAFVRVD---EVLASLKRTNVshgLLYGLINSDSQPHRNPDSKWYISPEEWPE 534
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397   208 DRYPPFCSGTGYVFSGDVASQVYNVSKS--VPYIKLEDVFVGlclerlnIRLEELHSqptffpGGLRFSVCLFRRI---- 281
Cdd:PLN03133 535 ETYPPWAHGPGYVVSRDIAKEVYKRHKEgrLKMFKLEDVAMG-------IWIAEMKK------EGLEVKYENDGRIyneg 601
                        250       260       270
                 ....*....|....*....|....*....|.
gi 5174397   282 -----VACHFIKPRTLLDYWQALENSRGEDC 307
Cdd:PLN03133 602 ckdgyVVAHYQSPREMLCLWQKLQEGKRATC 632
PLN03193 PLN03193
beta-1,3-galactosyltransferase; Provisional
65-256 2.16e-06

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 178735 [Multi-domain]  Cd Length: 408  Bit Score: 48.81  E-value: 2.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397    65 SSHKQlaeRMAIRQTW-----GKERMVKGKQLKTFFLLG--TTSSAAETKEVDQESQRHGDIIQKDFLDVYYNLTLKTMM 137
Cdd:PLN03193 150 SSRKR---RDSVRATWmpqgeKRKKLEEEKGIIIRFVIGhsATSGGILDRAIEAEDRKHGDFLRLDHVEGYLELSAKTKT 226
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5174397   138 GIE-----WvhrfcpQAAFVMKTDSDMFINVDYLTELLLKKNRTTRFFTGFLK----LNEFPIRqpfskwfVSKSEYpW- 207
Cdd:PLN03193 227 YFAtavamW------DADFYVKVDDDVHVNIATLGETLVRHRKKPRVYIGCMKsgpvLSQKGVR-------YHEPEY-Wk 292
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 5174397   208 -----DRYPPFCSGTGYVFSGDVASQVYNVSKSVPYIKLEDV-----FVGLCLERLNIR 256
Cdd:PLN03193 293 fgengNKYFRHATGQLYAISKDLASYISINQHVLHKYANEDVslgswFIGLDVEHIDDR 351
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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