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Conserved domains on  [gi|7661742|ref|NP_054766|]
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leydig cell tumor 10 kDa protein homolog [Homo sapiens]

Protein Classification

DUF2462 domain-containing protein( domain architecture ID 10559980)

DUF2462 domain-containing protein similar to Rattus norvegicus Leydig cell tumor 10 kDa protein, which may have a potential role in hypercalcemia of malignancy

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2462 pfam09495
Protein of unknown function (DUF2462); This protein is highly conserved, but its function is ...
 1-72 9.26e-10

Protein of unknown function (DUF2462); This protein is highly conserved, but its function is unknown. It can be isolated from HeLa cell nucleoli and is found to be homologous with Leydig cell tumour protein whose function is unknown.


:

Pssm-ID: 462817  Cd Length: 77  Bit Score: 50.34  E-value: 9.26e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 7661742     1 MAQGQRKfqahKPAKSKTAAAASEKNRGPRKGGRVIAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSS 72
Cdd:pfam09495  1 MAQGKLK----KKKKAKKAKRASKKAANPKKGARVIAPKKAKLVKQQKLKKKLTKGINKKTEKELASRAGSG 68
 
Name Accession Description Interval E-value
DUF2462 pfam09495
Protein of unknown function (DUF2462); This protein is highly conserved, but its function is ...
 1-72 9.26e-10

Protein of unknown function (DUF2462); This protein is highly conserved, but its function is unknown. It can be isolated from HeLa cell nucleoli and is found to be homologous with Leydig cell tumour protein whose function is unknown.


Pssm-ID: 462817  Cd Length: 77  Bit Score: 50.34  E-value: 9.26e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 7661742     1 MAQGQRKfqahKPAKSKTAAAASEKNRGPRKGGRVIAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSS 72
Cdd:pfam09495  1 MAQGKLK----KKKKAKKAKRASKKAANPKKGARVIAPKKAKLVKQQKLKKKLTKGINKKTEKELASRAGSG 68
 
Name Accession Description Interval E-value
DUF2462 pfam09495
Protein of unknown function (DUF2462); This protein is highly conserved, but its function is ...
 1-72 9.26e-10

Protein of unknown function (DUF2462); This protein is highly conserved, but its function is unknown. It can be isolated from HeLa cell nucleoli and is found to be homologous with Leydig cell tumour protein whose function is unknown.


Pssm-ID: 462817  Cd Length: 77  Bit Score: 50.34  E-value: 9.26e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 7661742     1 MAQGQRKfqahKPAKSKTAAAASEKNRGPRKGGRVIAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSS 72
Cdd:pfam09495  1 MAQGKLK----KKKKAKKAKRASKKAANPKKGARVIAPKKAKLVKQQKLKKKLTKGINKKTEKELASRAGSG 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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