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Conserved domains on  [gi|8922243|ref|NP_060474|]
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transmembrane protein 45A isoform 2 [Homo sapiens]

Protein Classification

TMEM45 family protein( domain architecture ID 10521718)

TMEM45 family protein is a DUF716 domain-containing protein; similar to Homo sapiens transmembrane epididymal protein 1 and transmembrane protein 45A/B

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF716 pfam04819
Family of unknown function (DUF716); This family is equally distributed in both metazoa and ...
 120-241 7.22e-44

Family of unknown function (DUF716); This family is equally distributed in both metazoa and plants. Annotation associated with Swiss:Q9SLW7 suggest that it may be involved in response to viral attack in plants. However, no clear function has been assigned to this family.


:

Pssm-ID: 461443  Cd Length: 138  Bit Score: 145.44  E-value: 7.22e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922243    120 VSLTKLMLSNALFVEAFIFYNHTHGREMLDIFVHQLLVLVVFLTGLVAFLEFLVRNNVLLELLRSSLILLQGSWFFQIGF 199
Cdd:pfam04819   1 SGLLFLLAALAFFQELLLFHFHSTDHSGLEGQYHLLLQLVIFLCLLSTLLEALLPKSFLADLVRSASILLQGLWFWQMGF 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 8922243    200 VLYPPS--------------GGPAWDL--MDHENILFLTICFCWHYAVTIVIVGMNYA 241
Cdd:pfam04819  81 MLYTPSfipggchdvcsgghGGVKCDSeeADHRAKALANLQFSWHVAFVLVFVVVLYA 138
 
Name Accession Description Interval E-value
DUF716 pfam04819
Family of unknown function (DUF716); This family is equally distributed in both metazoa and ...
 120-241 7.22e-44

Family of unknown function (DUF716); This family is equally distributed in both metazoa and plants. Annotation associated with Swiss:Q9SLW7 suggest that it may be involved in response to viral attack in plants. However, no clear function has been assigned to this family.


Pssm-ID: 461443  Cd Length: 138  Bit Score: 145.44  E-value: 7.22e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922243    120 VSLTKLMLSNALFVEAFIFYNHTHGREMLDIFVHQLLVLVVFLTGLVAFLEFLVRNNVLLELLRSSLILLQGSWFFQIGF 199
Cdd:pfam04819   1 SGLLFLLAALAFFQELLLFHFHSTDHSGLEGQYHLLLQLVIFLCLLSTLLEALLPKSFLADLVRSASILLQGLWFWQMGF 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 8922243    200 VLYPPS--------------GGPAWDL--MDHENILFLTICFCWHYAVTIVIVGMNYA 241
Cdd:pfam04819  81 MLYTPSfipggchdvcsgghGGVKCDSeeADHRAKALANLQFSWHVAFVLVFVVVLYA 138
 
Name Accession Description Interval E-value
DUF716 pfam04819
Family of unknown function (DUF716); This family is equally distributed in both metazoa and ...
 120-241 7.22e-44

Family of unknown function (DUF716); This family is equally distributed in both metazoa and plants. Annotation associated with Swiss:Q9SLW7 suggest that it may be involved in response to viral attack in plants. However, no clear function has been assigned to this family.


Pssm-ID: 461443  Cd Length: 138  Bit Score: 145.44  E-value: 7.22e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922243    120 VSLTKLMLSNALFVEAFIFYNHTHGREMLDIFVHQLLVLVVFLTGLVAFLEFLVRNNVLLELLRSSLILLQGSWFFQIGF 199
Cdd:pfam04819   1 SGLLFLLAALAFFQELLLFHFHSTDHSGLEGQYHLLLQLVIFLCLLSTLLEALLPKSFLADLVRSASILLQGLWFWQMGF 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 8922243    200 VLYPPS--------------GGPAWDL--MDHENILFLTICFCWHYAVTIVIVGMNYA 241
Cdd:pfam04819  81 MLYTPSfipggchdvcsgghGGVKCDSeeADHRAKALANLQFSWHVAFVLVFVVVLYA 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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