NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|33285006|ref|NP_061829|]
View 

sperm acrosome-associated protein 9 isoform b [Homo sapiens]

Protein Classification

sperm acrosome-associated protein 9( domain architecture ID 10633456)

sperm acrosome-associated protein 9 (SPACA9/C9orf9) that localizes to the acrosome and to the sperm tail is regulated by the Y-chromosome

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SPACA9 pfam15120
Sperm acrosome-associated protein 9; This family of proteins found in eukaryotes represents ...
 2-165 9.30e-97

Sperm acrosome-associated protein 9; This family of proteins found in eukaryotes represents sperm acrosome-associated protein 9 (SPACA9, previously known as C9orf9 or MAST). Sperm acrosome-associated protein 9 has been suggested to form a complex with calcium-binding proteins calreticulin and caldendrin localized to the acrosome. Despite this, no known protein interaction motifs have been identified in MAST/SPACA9.


:

Pssm-ID: 434475  Cd Length: 164  Bit Score: 276.68  E-value: 9.30e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33285006     2 NEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRRVLLMFLDICSELNKLCQ 81
Cdd:pfam15120   1 NDVAQQLRSLEQTYKLFKQQQFSFISALERGREQAHDKTTPVSSIGQVQSYLDHHCNNSTDRRILMMFLDICSDLNKLCQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33285006    82 HFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRK 161
Cdd:pfam15120  81 QLESSHSGRSTTNNLLEKCKTLLNPSNDLSNLRAKYPHDVVNHLSCDEARNHYGGVVSLIPIVLDCIKEWIENSEKLSRV 160


                  ....
gi 33285006   162 VLQH 165
Cdd:pfam15120 161 QQTV 164
 
Name Accession Description Interval E-value
SPACA9 pfam15120
Sperm acrosome-associated protein 9; This family of proteins found in eukaryotes represents ...
 2-165 9.30e-97

Sperm acrosome-associated protein 9; This family of proteins found in eukaryotes represents sperm acrosome-associated protein 9 (SPACA9, previously known as C9orf9 or MAST). Sperm acrosome-associated protein 9 has been suggested to form a complex with calcium-binding proteins calreticulin and caldendrin localized to the acrosome. Despite this, no known protein interaction motifs have been identified in MAST/SPACA9.


Pssm-ID: 434475  Cd Length: 164  Bit Score: 276.68  E-value: 9.30e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33285006     2 NEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRRVLLMFLDICSELNKLCQ 81
Cdd:pfam15120   1 NDVAQQLRSLEQTYKLFKQQQFSFISALERGREQAHDKTTPVSSIGQVQSYLDHHCNNSTDRRILMMFLDICSDLNKLCQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33285006    82 HFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRK 161
Cdd:pfam15120  81 QLESSHSGRSTTNNLLEKCKTLLNPSNDLSNLRAKYPHDVVNHLSCDEARNHYGGVVSLIPIVLDCIKEWIENSEKLSRV 160


                  ....
gi 33285006   162 VLQH 165
Cdd:pfam15120 161 QQTV 164
 
Name Accession Description Interval E-value
SPACA9 pfam15120
Sperm acrosome-associated protein 9; This family of proteins found in eukaryotes represents ...
 2-165 9.30e-97

Sperm acrosome-associated protein 9; This family of proteins found in eukaryotes represents sperm acrosome-associated protein 9 (SPACA9, previously known as C9orf9 or MAST). Sperm acrosome-associated protein 9 has been suggested to form a complex with calcium-binding proteins calreticulin and caldendrin localized to the acrosome. Despite this, no known protein interaction motifs have been identified in MAST/SPACA9.


Pssm-ID: 434475  Cd Length: 164  Bit Score: 276.68  E-value: 9.30e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33285006     2 NEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRRVLLMFLDICSELNKLCQ 81
Cdd:pfam15120   1 NDVAQQLRSLEQTYKLFKQQQFSFISALERGREQAHDKTTPVSSIGQVQSYLDHHCNNSTDRRILMMFLDICSDLNKLCQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33285006    82 HFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRK 161
Cdd:pfam15120  81 QLESSHSGRSTTNNLLEKCKTLLNPSNDLSNLRAKYPHDVVNHLSCDEARNHYGGVVSLIPIVLDCIKEWIENSEKLSRV 160


                  ....
gi 33285006   162 VLQH 165
Cdd:pfam15120 161 QQTV 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH