NCBI Conserved Domain Search

Fibronectin type 3 domain [General function prediction only];

3135-3513

2.20e-13

Fibronectin type 3 domain [General function prediction only];

The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 76.58 E-value: 2.20e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3135 VGPVSAIGVTEEETPSPTEPSTeAPEAPEEPLLGELTVTGSSPDSLSLSWTVP-QGRFDSFTVQYKDRDGQPQVVRVRGE 3213
Cdd:COG3401    23 VNALSKAGGSGKTILVYLAVVL-SVTTKESPGTLLVAAGLSSGGGLGTGGRAGtTSGVAAVAVAAAPPTATGLTTLTGSG 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3214 ESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQgPFDSFLVQ 3293
Cdd:COG3401   102 SVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSP-DTSATAAV 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3294 YRDAQGQPQAVPVSGDLRavavsgLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGeLTVTDATPDSVGLSW 3373
Cdd:COG3401   181 ATTSLTVTSTTLVDGGGD------IEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTG-LTATADTPGSVTLSW 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3374 T-VPEGEFDSFVVQYK-DKDGRLQVVpVAANQREVTVQGLEPSRKYRFLLYGLSGRkrlGPISADSTTAPLEKELPPHL- 3450
Cdd:COG3401   254 DpVTESDATGYRVYRSnSGDGPFTKV-ATVTTTSYTDTGLTNGTTYYYRVTAVDAA---GNESAPSNVVSVTTDLTPPAa 329

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 188528648 3451 -GELTVAEETSSSLRLSWT-VAQGPFDSFVVqYRDT--DGQPRAVPVAADQRTVTVEDLEPGKKYKF 3513
Cdd:COG3401   330 pSGLTATAVGSSSITLSWTaSSDADVTGYNV-YRSTsgGGTYTKIAETVTTTSYTDTGLTPGTTYYY 395

fn3

Fibronectin type III domain;

3756-3834

6.42e-13

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 67.05 E-value: 6.42e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3756 SPRDLQFSEIRETSAKVNWMPPPSRA---DSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEE 3831
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGNgpiTGYEVEYRPKNSGEPwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 188528648  3832 SEP 3834
Cdd:pfam00041   82 GPP 84

fn3

Fibronectin type III domain;

1988-2061

6.35e-12

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.97 E-value: 6.35e-12

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  1988 PRLGELTVTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGG 2061
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3 super family

Fibronectin type 3 domain [General function prediction only];

1426-1801

9.52e-12

Fibronectin type 3 domain [General function prediction only];

The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 71.19 E-value: 9.52e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1426 TVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQqeeTPPATESPLeprlgelTVTDVTPNSVGLSWT-VPEGQFDSF 1504
Cdd:COG3401   195 GGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPT---TPPSAPTGL-------TATADTPGSVTLSWDpVTESDATGY 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1505 IVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYkmnMYGL----HDGqrmgplsvvIVTAPLPPAPATEASKPPLEPRl 1580
Cdd:COG3401   265 RVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTY---YYRVtavdAAG---------NESAPSNVVSVTTDLTPPAAPS- 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1581 gELTVTDITPDSVGLSWT-VPEGEFDSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVS 1658
Cdd:COG3401   332 -GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGNESAPS 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1659 VEA---KTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPegqfDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGR 1735
Cdd:COG3401   411 EEVsatTASAASGESLTASVDAVPLTDVAGATAAASAASNPG----VSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTT 486

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648 1736 KYRFLLYGLLGKKR--HGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEG 1801
Cdd:COG3401   487 ANLSVTTGSLVGGSgaSSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLT 554

fn3

Fibronectin type III domain;

2304-2377

1.19e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 1.19e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  2304 PRLEELTVTDATPDSLSLSWTVPE---GQFDHFLVQYKNGDGQPKAT--RVPGHEDRVTISGLEPDNKYKMNLYGFHGG 2377
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNeiTVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2843-2923

1.22e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 1.22e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  2843 PRLGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQ--PKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2917
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*.
gi 188528648  2918 rVGPIS 2923
Cdd:pfam00041   81 -EGPPS 85

fn3

Fibronectin type III domain;

2629-2709

2.24e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.24e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  2629 PRLGELTMTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2703
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*.
gi 188528648  2704 rVGPIS 2709
Cdd:pfam00041   81 -EGPPS 85

fn3

Fibronectin type III domain;

3059-3132

2.51e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.51e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  3059 PRLGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 3132
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

1061-1141

2.61e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.61e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1061 GPPRlgELTVTDRTSDSLLLRWTVPE---GEFDSFVIQYKDRDGQ--PQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVG 1135
Cdd:pfam00041    1 SAPS--NLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78


                   ....*.
gi 188528648  1136 KKRHGP 1141
Cdd:pfam00041   79 GGEGPP 84

fn3

Fibronectin type III domain;

1265-1342

5.48e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 5.48e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1265 GELTVTGVTPDSLRLSWT---VAQGPFDSFMVQYKDAQGQ--PQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGrQRVG 1339
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG-GGEG 82


                   ...
gi 188528648  1340 PES 1342
Cdd:pfam00041   83 PPS 85

fn3

Fibronectin type III domain;

2198-2268

6.35e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 6.35e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2198 GQMTVRDITSDSLSLSWTVPE---GQFDHFLVQFKNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 2268
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

843-919

1.27e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 60.51 E-value: 1.27e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   843 PQDLRVVAVTPTTLELGWLRP---QAEVDRFVVSYVSAGNQRVRLE--VPPEADGTLLTDLMPGVEYVVTVTAERGRAVS 917
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEitVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82


                   ..
gi 188528648   918 YP 919
Cdd:pfam00041   83 PP 84

fn3

Fibronectin type III domain;

2526-2596

2.83e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 2.83e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2526 GELTVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEG 2596
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2099-2169

3.43e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 3.43e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2099 GELTVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEG 2169
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2743-2810

4.79e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.97 E-value: 4.79e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2743 TVTGSSPDSLSLSWTIP---QGHFDSFTVQYKDRDG--RPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEG 2810
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

3560-3635

5.70e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.58 E-value: 5.70e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3560 LTVTDTTPDSMRLSWS---VAQGPFDSFVVQYEDTNGQ--PQALLVDGDQSKILISGLEPSTPYRFLLYGLHeGKRLGPL 3634
Cdd:pfam00041    6 LTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVN-GGGEGPP 84


                   .
gi 188528648  3635 S 3635
Cdd:pfam00041   85 S 85

FN3 super family

Fibronectin type 3 domain [General function prediction only];

2418-2648

5.86e-10

Fibronectin type 3 domain [General function prediction only];

The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 65.41 E-value: 5.86e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2418 TVTGSSPDSLSLSWT-VPQGRFDSFTVqYKDRDGRPQVVRVGGE-ESEVTVGGLEPGRKYKmhlYglhegrRVGPVSTVG 2495
Cdd:COG3401   240 TATADTPGSVTLSWDpVTESDATGYRV-YRSNSGDGPFTKVATVtTTSYTDTGLTNGTTYY---Y------RVTAVDAAG 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2496 VTAPqedvdetPSPTEPGTEAPGPPEEPLlgELTVTGSSPDSLSLSWT-VPQGRFDSFTVQYKDR-DGRPQAVRVGGQES 2573
Cdd:COG3401   310 NESA-------PSNVVSVTTDLTPPAAPS--GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTT 380

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648 2574 KVTVRGLEPGRKYKmhlYGlhegrrlgpVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSW 2648
Cdd:COG3401   381 SYTDTGLTPGTTYY---YK---------VTAVDAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATA 443

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1156-1238

8.33e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 58.28 E-value: 8.33e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1156 PGTPphlGNLWVTDPTPDSLHLSWTVPE---GQFDTFMVQYRDRDGRP--QVVPVEGPERSFVVSSLDPDHKYRFTLFGI 1230
Cdd:cd00063     1 PSPP---TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77


                  ....*...
gi 188528648 1231 aNKKRYGP 1238
Cdd:cd00063    78 -NGGGESP 84

fn3

Fibronectin type III domain;

762-831

1.61e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.42 E-value: 1.61e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648   762 ETTVRTEWTPAP---GPVDAYEIQFIPTTEGaSPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLP 831
Cdd:pfam00041   13 STSLTVSWTPPPdgnGPITGYEVEYRPKNSG-EPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84

fn3

Fibronectin type III domain;

2957-3024

3.57e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 56.27 E-value: 3.57e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2957 TVTGSSPDSLSLSWTIP---QGRFDSFTVQYKDRDG--RPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEG 3024
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

3933-4010

7.22e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 55.50 E-value: 7.22e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3933 APRDLEAKEVTPRTALLTWTEPPVRPA---GYLLSFHTPGGQN--QEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSL 4007
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGNGpitGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 188528648  4008 LPP 4010
Cdd:pfam00041   82 GPP 84

fn3

Fibronectin type III domain;

3654-3736

1.88e-08

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.34 E-value: 1.88e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3654 PRLSQLSVTDVTTSSLRLNWEAPP---GAFDSFLLRFgvpSPSTLEPHPRpllqrELMVPGTRHSAVLRDLRSGTLYSLT 3730
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEY---RPKNSGEPWN-----EITVPGTTTSVTLTGLKPGTEYEVR 72


                   ....*.
gi 188528648  3731 LYGLRG 3736
Cdd:pfam00041   73 VQAVNG 78

fn3

Fibronectin type III domain;

1376-1446

3.19e-07

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 50.88 E-value: 3.19e-07

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  1376 GELTVTGSSPDSLSLFWTVP---QGSFDSFTVQYKDRDG--RPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEG 1446
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3 super family

Fibronectin type 3 domain [General function prediction only];

3812-4002

5.99e-07

Fibronectin type 3 domain [General function prediction only];

The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 55.78 E-value: 5.99e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3812 GLIPGARYEVTVVSVRGFEESEPLTGFL----TTVPDGPTQLRALNLTEGFAVLHWKPPQNP-VDTYDVQVTAPGAPPLQ 3886
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSvttpTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFT 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3887 AETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS--ITFTTGLE---APRDLEAKEVTPRTALLTWTEPP-VRPAG 3960
Cdd:COG3401   278 KVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSnvVSVTTDLTppaAPSGLTATAVGSSSITLSWTASSdADVTG 357

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 188528648 3961 YLL-SFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAM 4002
Cdd:COG3401   358 YNVyRSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAV 400

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1773-1862

7.92e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.80 E-value: 7.92e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1773 PPKPRlgeELQVTTVTQNSVGLSWTVPE---GQFDSFVVQYKDRDGQP--QVVPVEGSLREVSVPGLDPAHRYKLLLYGL 1847
Cdd:cd00063     1 PSPPT---NLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*
gi 188528648 1848 HHGKRVGPISAVAIT 1862
Cdd:cd00063    78 NGGGESPPSESVTVT 92

EGF_Tenascin super family

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

311-337

8.92e-07

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934 Cd Length: 29 Bit Score: 47.68 E-value: 8.92e-07

                           10        20
                   ....*....|....*....|....*..
gi 188528648   311 CPRGCSQRGRCKDGRCVCDPGYTGEDC 337
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

EGF_Tenascin super family

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

373-399

1.09e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934 Cd Length: 29 Bit Score: 47.68 E-value: 1.09e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   373 CPRDCRGRGRCEDGECICDTGYSGDDC 399
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

fn3

Fibronectin type III domain;

1885-1955

2.30e-06

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.18 E-value: 2.30e-06

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  1885 GELTVEEATSHTLHLSWM---VTEGEFDSFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

EGF_Tenascin super family

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

249-275

2.33e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934 Cd Length: 29 Bit Score: 46.52 E-value: 2.33e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   249 CPRGCSQRGRCEGGRCVCDPGYTGDDC 275
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

C_rich_MXAN6577 super family

cl49352

MXAN_6577-like cysteine-rich domain;

314-418

2.88e-06

MXAN_6577-like cysteine-rich domain;

The actual alignment was detected with superfamily member NF041328:

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 49.76 E-value: 2.88e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  314 GCSQRG-RCKDGRCVC-----DPGYTGEDCGtrSCPWDCGEGGRCVDGRCVCWPGYT--GEDC-STRTCPRDCRGRGR-- 382
Cdd:NF041328   13 GCPEPGaVCPEGLSVCggacvDLRSDPSNCG--ACGVACGAGQTCVAGACGCGPGTVacGGACvDTASDPAHCGACGAac 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 188528648  383 -----CEDGEC--ICDTGYS--GDDC-GVRSCPGDCNQRG-RCEDGR 418
Cdd:NF041328   91 apgqvCEGGACreACSEGLTrcGGACvDLATDPLHCGACGvACDPGE 137

EGF_Tenascin super family

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

559-585

3.45e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934 Cd Length: 29 Bit Score: 46.14 E-value: 3.45e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   559 CPGGCRGRGQCLDGRCVCEDGYSGEDC 585
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

PTZ00214 super family

cl31756

high cysteine membrane protein Group 4; Provisional

254-669

1.42e-05

high cysteine membrane protein Group 4; Provisional

The actual alignment was detected with superfamily member PTZ00214:

Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 51.46 E-value: 1.42e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  254 SQRGRCEGGRCVCDPGYTGddcGMRSCPRGCSQRGRCENGRCvcNPGYTGEDCgvRSCPRGCSqrgrcKDGRCVCDPGYT 333
Cdd:PTZ00214  341 SKNDDNNGDGYLCGDATNG---GVSGCATCGYNSGAVTCTRC--SAGYLGVDG--KSCSESCS-----GDTRGVCTKVAE 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  334 GEDCGTRSCpwdcgeggrcvdgRCVCWPGYTGEDCSTRTCPRDCrgrGRCEDGE---C-ICDTGYSGDDCGVRSCPGDCN 409
Cdd:PTZ00214  409 GSESTEVSC-------------RCVCKPTFYNSSGTCTPCTDSC---AVCKDGTptgCqQCSPGKILEFSIVSSESADCV 472

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  410 QRgrcedgrcvCWPGYTGTDCG-----SRACPRDCRGRGRCENGVCVCNagySGEDCGVRSCPG----DCRGRGRCESGR 480
Cdd:PTZ00214  473 DQ---------CSVGSECAECGitidgSRYCTRCKDASTYPFNGVCIPN---TQRDAYCTSTANgactTCSGAAFLMNGG 540

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  481 CMCWPGYTGRDCGTRACPGDC----RGRGRCVDGRCV-CNP---GFTGEDCGS-RRCPGDC---RGHGlCEDGVCV---- 544
Cdd:PTZ00214  541 CYTTEHYPGSTICDKQSNGKCtttkKGYGISPDGKLLeCDPtclACTAPGPGRcTRCPSDKllkRASG-AATGSCVdpga 619

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  545 CDAGY--SGEDCSTRSCPGgCRGRG------QCLDGRCVCEDGYSgedcgvrqCPNDCSQHGVCQD---GVCICW--EGY 611
Cdd:PTZ00214  620 CVDGYyaDGDACLPCATPG-CKTCGhasfctECAGELFVSLDGQS--------CLEECTGDKVVGEvsgGVRRCWceRGF 690

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648  612 V----SEDCSIRT-CPSNCHGRGRCEE-GRCL-CDPGYTGPTCATRMCPADCRGRGRCVQGVCLC 669
Cdd:PTZ00214  691 LpaldRSGCVLPTeCPPDMPSCAACDEsGRCLlCVTSGHNVQVDQRTCAEGCGARASSNQGVCMC 755

C_rich_MXAN6577 super family

cl49352

MXAN_6577-like cysteine-rich domain;

191-295

2.18e-04

MXAN_6577-like cysteine-rich domain;

The actual alignment was detected with superfamily member NF041328:

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 44.36 E-value: 2.18e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  191 CNDQGRCVRGRCVCFPGYTgpSCGwpscpgdcqgrGRCVQ--------GVC--VCRAGFSgpdCSQRSCPRGCSQ-RGRC 259
Cdd:NF041328   49 CGAGQTCVAGACGCGPGTV--ACG-----------GACVDtasdpahcGACgaACAPGQV---CEGGACREACSEgLTRC 112

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 188528648  260 eGGRCV---CDPGYTGdDCGmRSCPRGCSqrgrCENGRC 295
Cdd:NF041328  113 -GGACVdlaTDPLHCG-ACG-VACDPGES----CRGGAC 144

EGF_Tenascin super family

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

719-745

8.21e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934 Cd Length: 29 Bit Score: 39.59 E-value: 8.21e-04

                           10        20
                   ....*....|....*....|....*..
gi 188528648   719 CPGDCRGRGECHDGSCVCKDGYAGEDC 745
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

Name

Accession

Description

Interval

E-value

Fibrinogen_C

pfam00147

Fibrinogen beta and gamma chains, C-terminal globular domain;

4024-4233

7.78e-120

Fibrinogen beta and gamma chains, C-terminal globular domain;

Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 378.40 E-value: 7.78e-120

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  4024 FPRDCGEEMQNGAGASRTSTIFLNGNReRPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNIS-GEFWLGN 4102
Cdd:pfam00147    1 FGRDCSDVYNKGAKTSGLYTIRPDGAT-KPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSpGEFWLGN 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  4103 EALHSLTQAGDYSMRVDLRAG-DEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGD-------SMSYHSGSVFSARDRDPN 4174
Cdd:pfam00147   80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 188528648  4175 SLLISCAVSYRGAWWYRNCHYANLNG--LYGSTVDHQ-GVSWYHWKGFEFSVPFTEMKLRPR 4233
Cdd:pfam00147  160 SPDGNCALSYGGGWWYNNCHAANLNGvyYYGGTYSKQnGIIWATWKGRWYSMKKAEMKIRPL 221

FBG

smart00186

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ...

4024-4233

1.72e-112

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.

Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 356.97 E-value: 1.72e-112

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   4024 FPRDCGEEMQNGAGASRTSTIFLNGNReRPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNE 4103
Cdd:smart00186    1 LPRDCSDVLQNGGKTSGLYTIYPDGSS-RPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   4104 ALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGD-SMSYHSGSVFSARDRDPNSLLISCA 4181
Cdd:smart00186   80 NIHLLTSQGKYELRIDLEdWEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159

                           170       180       190       200       210
                    ....*....|....*....|....*....|....*....|....*....|...
gi 188528648   4182 VSYRGAWWYRNCHYANLNGLYGS-TVDHQGVSWYHWKGFEFSVPFTEMKLRPR 4233
Cdd:smart00186  160 EEYGGGWWYNNCHAANLNGRYYPnNNYDNGINWATWKGSWYSLKFTEMKIRPL 212

FReD

cd00087

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...

4023-4233

5.53e-110

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.

Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 350.00 E-value: 5.53e-110

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 4023 PFPRDCGEEMQNGAGASRTSTIFLNGNReRPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGN 4102
Cdd:cd00087     1 PLPRDCSEVLQRGGRTSGVYTIQPPGSN-EPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 4103 EALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCA 4181
Cdd:cd00087    80 EKIHLLTSQGPYELRIDLEdWEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648 4182 VSYRGAWWYRNCHYANLNGLYGSTVDHQ----GVSWYHWKGFEFSVPFTEMKLRPR 4233
Cdd:cd00087   160 ESYSGGWWYNSCHASNLNGRYYSGGHRNeydnGINWATWKGSTYSLKFTEMKIRPK 215

FN3

Fibronectin type 3 domain [General function prediction only];

3135-3513

2.20e-13

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 76.58 E-value: 2.20e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3135 VGPVSAIGVTEEETPSPTEPSTeAPEAPEEPLLGELTVTGSSPDSLSLSWTVP-QGRFDSFTVQYKDRDGQPQVVRVRGE 3213
Cdd:COG3401    23 VNALSKAGGSGKTILVYLAVVL-SVTTKESPGTLLVAAGLSSGGGLGTGGRAGtTSGVAAVAVAAAPPTATGLTTLTGSG 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3214 ESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQgPFDSFLVQ 3293
Cdd:COG3401   102 SVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSP-DTSATAAV 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3294 YRDAQGQPQAVPVSGDLRavavsgLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGeLTVTDATPDSVGLSW 3373
Cdd:COG3401   181 ATTSLTVTSTTLVDGGGD------IEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTG-LTATADTPGSVTLSW 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3374 T-VPEGEFDSFVVQYK-DKDGRLQVVpVAANQREVTVQGLEPSRKYRFLLYGLSGRkrlGPISADSTTAPLEKELPPHL- 3450
Cdd:COG3401   254 DpVTESDATGYRVYRSnSGDGPFTKV-ATVTTTSYTDTGLTNGTTYYYRVTAVDAA---GNESAPSNVVSVTTDLTPPAa 329

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 188528648 3451 -GELTVAEETSSSLRLSWT-VAQGPFDSFVVqYRDT--DGQPRAVPVAADQRTVTVEDLEPGKKYKF 3513
Cdd:COG3401   330 pSGLTATAVGSSSITLSWTaSSDADVTGYNV-YRSTsgGGTYTKIAETVTTTSYTDTGLTPGTTYYY 395

fn3

Fibronectin type III domain;

3756-3834

6.42e-13

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 67.05 E-value: 6.42e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3756 SPRDLQFSEIRETSAKVNWMPPPSRA---DSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEE 3831
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGNgpiTGYEVEYRPKNSGEPwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 188528648  3832 SEP 3834
Cdd:pfam00041   82 GPP 84

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3757-3836

3.95e-12

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 64.83 E-value: 3.95e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3757 PRDLQFSEIRETSAKVNWMPPP---SRADSFKVSYQLADGGEPQSVQVDGQARTQ-KLQGLIPGARYEVTVVSVRGFEES 3832
Cdd:cd00063     4 PTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSyTLTGLKPGTEYEFRVRAVNGGGES 83


                  ....
gi 188528648 3833 EPLT 3836
Cdd:cd00063    84 PPSE 87

fn3

Fibronectin type III domain;

1988-2061

6.35e-12

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.97 E-value: 6.35e-12

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  1988 PRLGELTVTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGG 2061
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3

Fibronectin type 3 domain [General function prediction only];

1426-1801

9.52e-12

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 71.19 E-value: 9.52e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1426 TVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQqeeTPPATESPLeprlgelTVTDVTPNSVGLSWT-VPEGQFDSF 1504
Cdd:COG3401   195 GGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPT---TPPSAPTGL-------TATADTPGSVTLSWDpVTESDATGY 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1505 IVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYkmnMYGL----HDGqrmgplsvvIVTAPLPPAPATEASKPPLEPRl 1580
Cdd:COG3401   265 RVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTY---YYRVtavdAAG---------NESAPSNVVSVTTDLTPPAAPS- 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1581 gELTVTDITPDSVGLSWT-VPEGEFDSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVS 1658
Cdd:COG3401   332 -GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGNESAPS 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1659 VEA---KTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPegqfDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGR 1735
Cdd:COG3401   411 EEVsatTASAASGESLTASVDAVPLTDVAGATAAASAASNPG----VSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTT 486

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648 1736 KYRFLLYGLLGKKR--HGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEG 1801
Cdd:COG3401   487 ANLSVTTGSLVGGSgaSSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLT 554

fn3

Fibronectin type III domain;

2304-2377

1.19e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 1.19e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  2304 PRLEELTVTDATPDSLSLSWTVPE---GQFDHFLVQYKNGDGQPKAT--RVPGHEDRVTISGLEPDNKYKMNLYGFHGG 2377
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNeiTVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2843-2923

1.22e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 1.22e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  2843 PRLGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQ--PKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2917
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*.
gi 188528648  2918 rVGPIS 2923
Cdd:pfam00041   81 -EGPPS 85

fn3

Fibronectin type III domain;

2629-2709

2.24e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.24e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  2629 PRLGELTMTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2703
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*.
gi 188528648  2704 rVGPIS 2709
Cdd:pfam00041   81 -EGPPS 85

fn3

Fibronectin type III domain;

3059-3132

2.51e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.51e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  3059 PRLGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 3132
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

3352-3434

2.54e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.54e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3352 PSPRlgELTVTDATPDSVGLSWTVPE---GEFDSFVVQYKDKDG--RLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSG 3426
Cdd:pfam00041    1 SAPS--NLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78


                   ....*...
gi 188528648  3427 rKRLGPIS 3434
Cdd:pfam00041   79 -GGEGPPS 85

fn3

Fibronectin type III domain;

1061-1141

2.61e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.61e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1061 GPPRlgELTVTDRTSDSLLLRWTVPE---GEFDSFVIQYKDRDGQ--PQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVG 1135
Cdd:pfam00041    1 SAPS--NLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78


                   ....*.
gi 188528648  1136 KKRHGP 1141
Cdd:pfam00041   79 GGEGPP 84

fn3

Fibronectin type III domain;

1265-1342

5.48e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 5.48e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1265 GELTVTGVTPDSLRLSWT---VAQGPFDSFMVQYKDAQGQ--PQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGrQRVG 1339
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG-GGEG 82


                   ...
gi 188528648  1340 PES 1342
Cdd:pfam00041   83 PPS 85

fn3

Fibronectin type III domain;

2198-2268

6.35e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 6.35e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2198 GQMTVRDITSDSLSLSWTVPE---GQFDHFLVQFKNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 2268
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

843-919

1.27e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 60.51 E-value: 1.27e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   843 PQDLRVVAVTPTTLELGWLRP---QAEVDRFVVSYVSAGNQRVRLE--VPPEADGTLLTDLMPGVEYVVTVTAERGRAVS 917
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEitVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82


                   ..
gi 188528648   918 YP 919
Cdd:pfam00041   83 PP 84

fn3

Fibronectin type III domain;

1578-1643

1.46e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 60.12 E-value: 1.46e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 188528648  1578 PRLGELTVTDITPDSVGLSWTVPE---GEFDSFVVQYKDRDGQ--PQVVPVAADQREVTIPDLEPSRKYKF 1643
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEV 71

fn3

Fibronectin type III domain;

2526-2596

2.83e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 2.83e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2526 GELTVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEG 2596
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2099-2169

3.43e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 3.43e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2099 GELTVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEG 2169
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2743-2810

4.79e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.97 E-value: 4.79e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2743 TVTGSSPDSLSLSWTIP---QGHFDSFTVQYKDRDG--RPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEG 2810
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

3560-3635

5.70e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.58 E-value: 5.70e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3560 LTVTDTTPDSMRLSWS---VAQGPFDSFVVQYEDTNGQ--PQALLVDGDQSKILISGLEPSTPYRFLLYGLHeGKRLGPL 3634
Cdd:pfam00041    6 LTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVN-GGGEGPP 84


                   .
gi 188528648  3635 S 3635
Cdd:pfam00041   85 S 85

FN3

Fibronectin type 3 domain [General function prediction only];

2418-2648

5.86e-10

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 65.41 E-value: 5.86e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2418 TVTGSSPDSLSLSWT-VPQGRFDSFTVqYKDRDGRPQVVRVGGE-ESEVTVGGLEPGRKYKmhlYglhegrRVGPVSTVG 2495
Cdd:COG3401   240 TATADTPGSVTLSWDpVTESDATGYRV-YRSNSGDGPFTKVATVtTTSYTDTGLTNGTTYY---Y------RVTAVDAAG 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2496 VTAPqedvdetPSPTEPGTEAPGPPEEPLlgELTVTGSSPDSLSLSWT-VPQGRFDSFTVQYKDR-DGRPQAVRVGGQES 2573
Cdd:COG3401   310 NESA-------PSNVVSVTTDLTPPAAPS--GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTT 380

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648 2574 KVTVRGLEPGRKYKmhlYGlhegrrlgpVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSW 2648
Cdd:COG3401   381 SYTDTGLTPGTTYY---YK---------VTAVDAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATA 443

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1156-1238

8.33e-10

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 58.28 E-value: 8.33e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1156 PGTPphlGNLWVTDPTPDSLHLSWTVPE---GQFDTFMVQYRDRDGRP--QVVPVEGPERSFVVSSLDPDHKYRFTLFGI 1230
Cdd:cd00063     1 PSPP---TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77


                  ....*...
gi 188528648 1231 aNKKRYGP 1238
Cdd:cd00063    78 -NGGGESP 84

fn3

Fibronectin type III domain;

2418-2485

1.51e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.42 E-value: 1.51e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2418 TVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEG 2485
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

762-831

1.61e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.42 E-value: 1.61e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648   762 ETTVRTEWTPAP---GPVDAYEIQFIPTTEGaSPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLP 831
Cdd:pfam00041   13 STSLTVSWTPPPdgnGPITGYEVEYRPKNSG-EPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1062-1131

2.12e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 57.12 E-value: 2.12e-09

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648 1062 PPRLGELTVTDRTSDSLLLRWTVPE---GEFDSFVIQYKDRDGQP--QVVPVEGPQRSAVITSLDPGRKYKFVLY 1131
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1575-1663

2.82e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 2.82e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1575 PLEPRlgELTVTDITPDSVGLSWTVPE---GEFDSFVVQYKDRDGQP--QVVPVAADQREVTIPDLEPSRKYKFLLFGIq 1649
Cdd:cd00063     1 PSPPT--NLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV- 77

                          90
                  ....*....|....*.
gi 188528648 1650 DGKRRSPVS--VEAKT 1663
Cdd:cd00063    78 NGGGESPPSesVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1156-1227

3.38e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 56.47 E-value: 3.38e-09

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 188528648   1156 PGTPPhlgNLWVTDPTPDSLHLSWTVPE-----GQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTL 1227
Cdd:smart00060    1 PSPPS---NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRV 74

fn3

Fibronectin type III domain;

2957-3024

3.57e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 56.27 E-value: 3.57e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2957 TVTGSSPDSLSLSWTIP---QGRFDSFTVQYKDRDG--RPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEG 3024
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3

Fibronectin type 3 domain [General function prediction only];

1223-1496

3.89e-09

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 62.71 E-value: 3.89e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1223 YRFTLFGIANKKRYGP--LTADGTTAPErkeePPrpefleqpllGELTVTGVTPDSLRLSWT-VAQGPFDSFMVQYKDAQ 1299
Cdd:COG3401   207 YRVAATDTGGESAPSNevSVTTPTTPPS----AP----------TGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSG 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1300 GQPQAVPVAGDENEVTVPGLDPDRKYKmnlYGLRGRQRVGPESvvaktapqedvdeTPSPTELGTEAPESPEEPLlgELT 1379
Cdd:COG3401   273 DGPFTKVATVTTTSYTDTGLTNGTTYY---YRVTAVDAAGNES-------------APSNVVSVTTDLTPPAAPS--GLT 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1380 VTGSSPDSLSLFWT-VPQGSFDSFTVQYKDR-DGRPRAVRVGGKESEVTVGGLEPGHKYK-----MHLYGLhEGQRVGPV 1452
Cdd:COG3401   335 ATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTTSYTDTGLTPGTTYYykvtaVDAAGN-ESAPSEEV 413

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 188528648 1453 SAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTV 1496
Cdd:COG3401   414 SATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAV 457

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3159-3250

4.29e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.35 E-value: 4.29e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3159 PEAPEEpllgeLTVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGQP--QVVRVRGEESEVTVGGLEPGRKYKMHLY 3233
Cdd:cd00063     1 PSPPTN-----LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 3234 GLHEGQRVGPVSTVGIT 3250
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1061-1128

6.25e-09

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 55.70 E-value: 6.25e-09

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648   1061 GPPRlgELTVTDRTSDSLLLRWTVPE-----GEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKF 1128
Cdd:smart00060    2 SPPS--NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

fn3

Fibronectin type III domain;

3933-4010

7.22e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 55.50 E-value: 7.22e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3933 APRDLEAKEVTPRTALLTWTEPPVRPA---GYLLSFHTPGGQN--QEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSL 4007
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGNGpitGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 188528648  4008 LPP 4010
Cdd:pfam00041   82 GPP 84

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

841-921

8.65e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 55.58 E-value: 8.65e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  841 DGPQDLRVVAVTPTTLELGWLRPQ---AEVDRFVVSYVSAGNQRVRLEVPPEADGT--LLTDLMPGVEYVVTVTAERGRA 915
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETsyTLTGLKPGTEYEFRVRAVNGGG 81


                  ....*.
gi 188528648  916 VSYPAS 921
Cdd:cd00063    82 ESPPSE 87

fn3

Fibronectin type III domain;

1163-1240

1.35e-08

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.73 E-value: 1.35e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1163 GNLWVTDPTPDSLHLSWTVPE---GQFDTFMVQYRDRDG--RPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIaNKKRYG 1237
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV-NGGGEG 82


                   ...
gi 188528648  1238 PLT 1240
Cdd:pfam00041   83 PPS 85

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2837-2928

1.42e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 54.81 E-value: 1.42e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2837 PEPPnkprlGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQP--KVVRVPGHEDGVTISGLEPDHKYKMNLY 2911
Cdd:cd00063     1 PSPP-----TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 2912 GFHGGQRVGPISVIGVT 2928
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1575-1643

1.71e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.16 E-value: 1.71e-08

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648   1575 PLEPRlgELTVTDITPDSVGLSWTVPE-----GEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKF 1643
Cdd:smart00060    1 PSPPS--NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

fn3

Fibronectin type III domain;

3654-3736

1.88e-08

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.34 E-value: 1.88e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3654 PRLSQLSVTDVTTSSLRLNWEAPP---GAFDSFLLRFgvpSPSTLEPHPRpllqrELMVPGTRHSAVLRDLRSGTLYSLT 3730
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEY---RPKNSGEPWN-----EITVPGTTTSVTLTGLKPGTEYEVR 72


                   ....*.
gi 188528648  3731 LYGLRG 3736
Cdd:pfam00041   73 VQAVNG 78

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3359-3419

2.02e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.16 E-value: 2.02e-08

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648   3359 LTVTDATPDSVGLSWTVPE-----GEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRF 3419
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2307-2389

2.63e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 54.04 E-value: 2.63e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2307 EELTVTDATPDSLSLSWTVPE---GQFDHFLVQYKNGDGQP--KATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVG 2381
Cdd:cd00063     5 TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESP 84


                  ....*...
gi 188528648 2382 PVSAIGVT 2389
Cdd:cd00063    85 PSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3756-3832

2.95e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 2.95e-08

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   3756 SPRDLQFSEIRETSAKVNWMPPPS-RADSFKVSYQLADGGEP---QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEE 3831
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPDdGITGYIVGYRVEYREEGsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGE 82


                    .
gi 188528648   3832 S 3832
Cdd:smart00060   83 G 83

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1993-2073

3.59e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.65 E-value: 3.59e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1993 LTVTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQP--KAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPV 2067
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPS 86


                  ....*.
gi 188528648 2068 SVVGVT 2073
Cdd:cd00063    87 ESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

841-914

4.12e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.39 E-value: 4.12e-08

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648    841 DGPQDLRVVAVTPTTLELGWLRPQAE-----VDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGR 914
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3053-3144

4.59e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 4.59e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3053 PEPPikprlGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQP--KAVRVPGHEDGVTISGLEPDHKYKMNLY 3127
Cdd:cd00063     1 PSPP-----TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 3128 GFHGGQRVGPVSAIGVT 3144
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2517-2591

5.80e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 5.80e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2517 PGPPEEpllgeLTVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGRP--QAVRVGGQESKVTVRGLEPGRKYKMHLY 2591
Cdd:cd00063     1 PSPPTN-----LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2101-2181

5.97e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 5.97e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2101 LTVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPV 2175
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPS 86


                  ....*.
gi 188528648 2176 SAVGVT 2181
Cdd:cd00063    87 ESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2517-2591

7.62e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 52.62 E-value: 7.62e-08

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2517 PGPPEEpllgeLTVTGSSPDSLSLSWTVPQ-----GRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLY 2591
Cdd:smart00060    1 PSPPSN-----LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2418-2497

1.38e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 52.11 E-value: 1.38e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2418 TVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2492
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSE 87


                  ....*
gi 188528648 2493 TVGVT 2497
Cdd:cd00063    88 SVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2623-2714

1.44e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 52.11 E-value: 1.44e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2623 PEPPIKPRLgeltmTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQP--KAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
Cdd:cd00063     1 PSPPTNLRV-----TDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 2698 GFHGGQRVGPISVIGVT 2714
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1267-1347

1.65e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.73 E-value: 1.65e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1267 LTVTGVTPDSLRLSWTVAQ---GPFDSFMVQYKDAQGQP--QAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGP- 1340
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPs 86


                  ....*..
gi 188528648 1341 ESVVAKT 1347
Cdd:cd00063    87 ESVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3560-3639

2.10e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.73 E-value: 2.10e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3560 LTVTDTTPDSMRLSWSVAQ---GPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRlGPL 3634
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE-SPP 85


                  ....*
gi 188528648 3635 SAEGT 3639
Cdd:cd00063    86 SESVT 90

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2837-2911

2.88e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 50.69 E-value: 2.88e-07

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2837 PEPPnkprlGELTVTDATPDSLSLSWMVPE-----GQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLY 2911
Cdd:smart00060    1 PSPP-----SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

fn3

Fibronectin type III domain;

1376-1446

3.19e-07

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 50.88 E-value: 3.19e-07

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  1376 GELTVTGSSPDSLSLFWTVP---QGSFDSFTVQYKDRDG--RPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEG 1446
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3560-3620

5.43e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 5.43e-07

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648   3560 LTVTDTTPDSMRLSWS-----VAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRF 3620
Cdd:smart00060    7 LRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3053-3127

5.99e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 5.99e-07

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   3053 PEPPikprlGELTVTDATPDSLSLSWMVPE-----GQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 3127
Cdd:smart00060    1 PSPP-----SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain [General function prediction only];

3812-4002

5.99e-07

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 55.78 E-value: 5.99e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3812 GLIPGARYEVTVVSVRGFEESEPLTGFL----TTVPDGPTQLRALNLTEGFAVLHWKPPQNP-VDTYDVQVTAPGAPPLQ 3886
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSvttpTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFT 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3887 AETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS--ITFTTGLE---APRDLEAKEVTPRTALLTWTEPP-VRPAG 3960
Cdd:COG3401   278 KVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSnvVSVTTDLTppaAPSGLTATAVGSSSITLSWTASSdADVTG 357

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 188528648 3961 YLL-SFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAM 4002
Cdd:COG3401   358 YNVyRSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAV 400

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2101-2164

6.05e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 6.05e-07

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   2101 LTVTGSSPDSLSLSWTVPQ-----GRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2164
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2743-2822

7.61e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.80 E-value: 7.61e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2743 TVTGSSPDSLSLSWTIPQ---GHFDSFTVQYKDRDGRP--QVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSE 87


                  ....*
gi 188528648 2818 TVGVT 2822
Cdd:cd00063    88 SVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1773-1862

7.92e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.80 E-value: 7.92e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1773 PPKPRlgeELQVTTVTQNSVGLSWTVPE---GQFDSFVVQYKDRDGQP--QVVPVEGSLREVSVPGLDPAHRYKLLLYGL 1847
Cdd:cd00063     1 PSPPT---NLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*
gi 188528648 1848 HHGKRVGPISAVAIT 1862
Cdd:cd00063    78 NGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2957-3036

8.15e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.80 E-value: 8.15e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2957 TVTGSSPDSLSLSWTIPQ---GRFDSFTVQYKDRDGRP--QVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVS 3031
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSE 87


                  ....*
gi 188528648 3032 AVGVT 3036
Cdd:cd00063    88 SVTVT 92

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

311-337

8.92e-07

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 47.68 E-value: 8.92e-07

                           10        20
                   ....*....|....*....|....*..
gi 188528648   311 CPRGCSQRGRCKDGRCVCDPGYTGEDC 337
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1993-2056

9.58e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.54 E-value: 9.58e-07

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   1993 LTVTDATPDSLSLSWTVPE-----GQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLY 2056
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2188-2277

1.02e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.42 E-value: 1.02e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2188 PDAPlaklrlGQMTVRDITSDSLSLSWTVPE---GQFDHFLVQFKNGDGQP--KAVRVPGHEDGVTISGLEPDHKYKMNL 2262
Cdd:cd00063     1 PSPP------TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRV 74

                          90
                  ....*....|....*
gi 188528648 2263 YGFHGGQRVGPVSAV 2277
Cdd:cd00063    75 RAVNGGGESPPSESV 89

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3932-4017

1.03e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.42 E-value: 1.03e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3932 EAPRDLEAKEVTPRTALLTWTEPPVRPA---GYLLSFHTPGGQNQEILLPGGI--TSHQLLGLFPSTSYNARLQAM--WG 4004
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDGGpitGYVVEYREKGSGDWKEVEVTPGseTSYTLTGLKPGTEYEFRVRAVngGG 81

                          90
                  ....*....|...
gi 188528648 4005 QSlLPPVSTSFTT 4017
Cdd:cd00063    82 ES-PPSESVTVTT 93

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

373-399

1.09e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 47.68 E-value: 1.09e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   373 CPRDCRGRGRCEDGECICDTGYSGDDC 399
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1370-1458

1.28e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.42 E-value: 1.28e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1370 PEEPllGELTVTGSSPDSLSLFWTVPQ---GSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLH 1444
Cdd:cd00063     1 PSPP--TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....
gi 188528648 1445 EGQRVGPVSAVGVT 1458
Cdd:cd00063    79 GGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3933-4001

1.31e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.15 E-value: 1.31e-06

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648   3933 APRDLEAKEVTPRTALLTWTEPPVRPA-----GYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQA 4001
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPDDGItgyivGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1267-1330

1.55e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 1.55e-06

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   1267 LTVTGVTPDSLRLSWT-----VAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLY 1330
Cdd:smart00060    7 LRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2623-2697

1.58e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 1.58e-06

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2623 PEPPikprlGELTMTDATPDSLSLSWTVPE-----GQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
Cdd:smart00060    1 PSPP-----SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

fn3

Fibronectin type III domain;

1774-1857

1.70e-06

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.57 E-value: 1.70e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1774 PKPRlgeELQVTTVTQNSVGLSWTVPE---GQFDSFVVQYKDRDGQ--PQVVPVEGSLREVSVPGLDPAHRYKLLLYGlH 1848
Cdd:pfam00041    1 SAPS---NLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQA-V 76


                   ....*....
gi 188528648  1849 HGKRVGPIS 1857
Cdd:pfam00041   77 NGGGEGPPS 85

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2418-2480

2.22e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.38 E-value: 2.22e-06

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648   2418 TVTGSSPDSLSLSWTVPQ-----GRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

fn3

Fibronectin type III domain;

1885-1955

2.30e-06

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.18 E-value: 2.30e-06

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  1885 GELTVEEATSHTLHLSWM---VTEGEFDSFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

249-275

2.33e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 46.52 E-value: 2.33e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   249 CPRGCSQRGRCEGGRCVCDPGYTGDDC 275
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

314-418

2.88e-06

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 49.76 E-value: 2.88e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  314 GCSQRG-RCKDGRCVC-----DPGYTGEDCGtrSCPWDCGEGGRCVDGRCVCWPGYT--GEDC-STRTCPRDCRGRGR-- 382
Cdd:NF041328   13 GCPEPGaVCPEGLSVCggacvDLRSDPSNCG--ACGVACGAGQTCVAGACGCGPGTVacGGACvDTASDPAHCGACGAac 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 188528648  383 -----CEDGEC--ICDTGYS--GDDC-GVRSCPGDCNQRG-RCEDGR 418
Cdd:NF041328   91 apgqvCEGGACreACSEGLTrcGGACvDLATDPLHCGACGvACDPGE 137

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

753-838

3.32e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 48.26 E-value: 3.32e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  753 EGMRMHLLEETTVRTEWTPAP---GPVDAYEIQFIPTTEGASPPFTARVPSSASaYDQRGLAPGQEYQVTVRALRGTSWG 829
Cdd:cd00063     5 TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETS-YTLTGLKPGTEYEFRVRAVNGGGES 83

                          90
                  ....*....|
gi 188528648  830 LPA-SKTITT 838
Cdd:cd00063    84 PPSeSVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2307-2372

3.38e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 47.99 E-value: 3.38e-06

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 188528648   2307 EELTVTDATPDSLSLSWTVPE-----GQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLY 2372
Cdd:smart00060    5 SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

559-585

3.45e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 46.14 E-value: 3.45e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   559 CPGGCRGRGQCLDGRCVCEDGYSGEDC 585
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2188-2263

6.77e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.84 E-value: 6.77e-06

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2188 PDAPlaklrlGQMTVRDITSDSLSLSWTVPE-----GQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 2262
Cdd:smart00060    1 PSPP------SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRV 74


                    .
gi 188528648   2263 Y 2263
Cdd:smart00060   75 R 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3843-3929

7.33e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 47.11 E-value: 7.33e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3843 PDGPTQLRALNLTEGFAVLHWKPPQN---PVDTYDVQVTAPGAPPLQ--AETPGSAVDYPLHDLVLHTNYTATVRGLRGP 3917
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEDdggPITGYVVEYREKGSGDWKevEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|...
gi 188528648 3918 NLTSPA-SITFTT 3929
Cdd:cd00063    81 GESPPSeSVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2957-3019

7.39e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.84 E-value: 7.39e-06

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648   2957 TVTGSSPDSLSLSWTIPQ-----GRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLY 3019
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1773-1842

9.17e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.45 E-value: 9.17e-06

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648   1773 PPKPRlgeELQVTTVTQNSVGLSWTVPE-----GQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKL 1842
Cdd:smart00060    1 PSPPS---NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2743-2805

1.04e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.45 E-value: 1.04e-05

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648   2743 TVTGSSPDSLSLSWTIPQ-----GHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLY 2805
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

PTZ00214

high cysteine membrane protein Group 4; Provisional

254-669

1.42e-05

high cysteine membrane protein Group 4; Provisional

Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 51.46 E-value: 1.42e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  254 SQRGRCEGGRCVCDPGYTGddcGMRSCPRGCSQRGRCENGRCvcNPGYTGEDCgvRSCPRGCSqrgrcKDGRCVCDPGYT 333
Cdd:PTZ00214  341 SKNDDNNGDGYLCGDATNG---GVSGCATCGYNSGAVTCTRC--SAGYLGVDG--KSCSESCS-----GDTRGVCTKVAE 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  334 GEDCGTRSCpwdcgeggrcvdgRCVCWPGYTGEDCSTRTCPRDCrgrGRCEDGE---C-ICDTGYSGDDCGVRSCPGDCN 409
Cdd:PTZ00214  409 GSESTEVSC-------------RCVCKPTFYNSSGTCTPCTDSC---AVCKDGTptgCqQCSPGKILEFSIVSSESADCV 472

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  410 QRgrcedgrcvCWPGYTGTDCG-----SRACPRDCRGRGRCENGVCVCNagySGEDCGVRSCPG----DCRGRGRCESGR 480
Cdd:PTZ00214  473 DQ---------CSVGSECAECGitidgSRYCTRCKDASTYPFNGVCIPN---TQRDAYCTSTANgactTCSGAAFLMNGG 540

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  481 CMCWPGYTGRDCGTRACPGDC----RGRGRCVDGRCV-CNP---GFTGEDCGS-RRCPGDC---RGHGlCEDGVCV---- 544
Cdd:PTZ00214  541 CYTTEHYPGSTICDKQSNGKCtttkKGYGISPDGKLLeCDPtclACTAPGPGRcTRCPSDKllkRASG-AATGSCVdpga 619

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  545 CDAGY--SGEDCSTRSCPGgCRGRG------QCLDGRCVCEDGYSgedcgvrqCPNDCSQHGVCQD---GVCICW--EGY 611
Cdd:PTZ00214  620 CVDGYyaDGDACLPCATPG-CKTCGhasfctECAGELFVSLDGQS--------CLEECTGDKVVGEvsgGVRRCWceRGF 690

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648  612 V----SEDCSIRT-CPSNCHGRGRCEE-GRCL-CDPGYTGPTCATRMCPADCRGRGRCVQGVCLC 669
Cdd:PTZ00214  691 LpaldRSGCVLPTeCPPDMPSCAACDEsGRCLlCVTSGHNVQVDQRTCAEGCGARASSNQGVCMC 755

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

280-306

1.69e-05

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 44.21 E-value: 1.69e-05

                           10        20
                   ....*....|....*....|....*..
gi 188528648   280 CPRGCSQRGRCENGRCVCNPGYTGEDC 306
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1378-1441

1.73e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 45.68 E-value: 1.73e-05

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   1378 LTVTGSSPDSLSLFWTVPQGS-----FDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLY 1441
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

fn3

Fibronectin type III domain;

3846-3916

2.55e-05

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 45.48 E-value: 2.55e-05

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  3846 PTQLRALNLTEGFAVLHWKPP---QNPVDTYDVQVTAPGAPPLQAE--TPGSAVDYPLHDLVLHTNYTATVRGLRG 3916
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEitVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3657-3732

3.68e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.91 E-value: 3.68e-05

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 188528648   3657 SQLSVTDVTTSSLRLNWEAPPGA-FDSFLLRFgvpspsTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLY 3732
Cdd:smart00060    5 SNLRVTDVTSTSVTLSWEPPPDDgITGYIVGY------RVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

244-356

5.30e-05

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 46.29 E-value: 5.30e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  244 CSQRS--CPRGCSqrgRCeGGRCVcdpGYTGD--DCGmrSCPRGCSQRGRCENGRCVCNPGytGEDCG-----VRSCPRG 314
Cdd:NF041328   14 CPEPGavCPEGLS---VC-GGACV---DLRSDpsNCG--ACGVACGAGQTCVAGACGCGPG--TVACGgacvdTASDPAH 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648  315 CSQRGR-------CKDGRC--VCDPGYTgeDCGtRSC------PWDCGE-GGRCVDGR 356
Cdd:NF041328   83 CGACGAacapgqvCEGGACreACSEGLT--RCG-GACvdlatdPLHCGAcGVACDPGE 137

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3843-3912

9.14e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 43.76 E-value: 9.14e-05

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648   3843 PDGPTQLRALNLTEGFAVLHWKPPQNP-----VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 3912
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1887-1955

1.39e-04

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 43.37 E-value: 1.39e-04

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648   1887 LTVEEATSHTLHLSWM-----VTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
Cdd:smart00060    7 LRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

191-295

2.18e-04

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 44.36 E-value: 2.18e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  191 CNDQGRCVRGRCVCFPGYTgpSCGwpscpgdcqgrGRCVQ--------GVC--VCRAGFSgpdCSQRSCPRGCSQ-RGRC 259
Cdd:NF041328   49 CGAGQTCVAGACGCGPGTV--ACG-----------GACVDtasdpahcGACgaACAPGQV---CEGGACREACSEgLTRC 112

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 188528648  260 eGGRCV---CDPGYTGdDCGmRSCPRGCSqrgrCENGRC 295
Cdd:NF041328  113 -GGACVdlaTDPLHCG-ACG-VACDPGES----CRGGAC 144

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1887-1955

2.41e-04

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 42.87 E-value: 2.41e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648 1887 LTVEEATSHTLHLSWMV---TEGEFDSFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPpedDGGPITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

221-244

2.96e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 40.41 E-value: 2.96e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   221 DCQGRGRCVQ--GVCVCRAGFSGPDC 244
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

342-369

3.29e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 40.74 E-value: 3.29e-04

                           10        20
                   ....*....|....*....|....*...
gi 188528648   342 CPWDCGEGGRCVDGRCVCWPGYTGEDCS 369
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3657-3732

3.53e-04

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 42.48 E-value: 3.53e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648 3657 SQLSVTDVTTSSLRLNWEAPP---GAFDSFLLRFGVPSPSTLEPHPRPllqrelmvPGTRHSAVLRDLRSGTLYSLTLY 3732
Cdd:cd00063     5 TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVT--------PGSETSYTLTGLKPGTEYEFRVR 75

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

571-703

7.41e-04

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 42.82 E-value: 7.41e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  571 DGRCVCEDGySGEDCGVrqCPNDCSQHGVCQDGVCICWEGYVS--EDC-SIRTCPSNCHGRG-RCEEGRclcdpgytgpT 646
Cdd:NF041328   29 GGACVDLRS-DPSNCGA--CGVACGAGQTCVAGACGCGPGTVAcgGACvDTASDPAHCGACGaACAPGQ----------V 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648  647 CATRMCPADC-RGRGRCvQGVCLcHVGYGGEDCGqeeppasACPGGCGPRELCRAGQC 703
Cdd:NF041328   96 CEGGACREACsEGLTRC-GGACV-DLATDPLHCG-------ACGVACDPGESCRGGAC 144

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

753-829

7.50e-04

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 41.06 E-value: 7.50e-04

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648    753 EGMRMHLLEETTVRTEWTPAPGP-VDAYEIQFIPTTEGASPPF-TARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWG 829
Cdd:smart00060    5 SNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSEWkEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

492-581

8.00e-04

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 42.82 E-value: 8.00e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  492 CGtrACPGDCRGRGRCVDGRCVCNPGFT--GEDCGSRR--------CPGDCRGHGLCEDGVC--VCDAGYsgEDCStRSC 559
Cdd:NF041328   42 CG--ACGVACGAGQTCVAGACGCGPGTVacGGACVDTAsdpahcgaCGAACAPGQVCEGGACreACSEGL--TRCG-GAC 116

                          90       100
                  ....*....|....*....|....
gi 188528648  560 PGGCRGRGQCldGRC--VCEDGYS 581
Cdd:NF041328  117 VDLATDPLHC--GACgvACDPGES 138

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

719-745

8.21e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.59 E-value: 8.21e-04

                           10        20
                   ....*....|....*....|....*..
gi 188528648   719 CPGDCRGRGECHDGSCVCKDGYAGEDC 745
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

GGGWT_bact

NF040941

fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ...

4053-4067

1.79e-03

fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.

Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 38.70 E-value: 1.79e-03

                          10
                  ....*....|....*
gi 188528648 4053 PLNVFCDMETDGGGW 4067
Cdd:NF040941   29 PFQVYCDMTTDGGGW 43

FN3

Fibronectin type 3 domain [General function prediction only];

3560-3679

2.79e-03

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 43.84 E-value: 2.79e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3560 LTVTDTTPDSMRLSWS-VAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS--A 3636
Cdd:COG3401   239 LTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSnvV 318

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 188528648 3637 EGTTGLAPAGQTSEesrprlsqLSVTDVTTSSLRLNWEAPPGA 3679
Cdd:COG3401   319 SVTTDLTPPAAPSG--------LTATAVGSSSITLSWTASSDA 353

Name

Accession

Description

Interval

E-value

Fibrinogen_C

pfam00147

Fibrinogen beta and gamma chains, C-terminal globular domain;

4024-4233

7.78e-120

Fibrinogen beta and gamma chains, C-terminal globular domain;

Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 378.40 E-value: 7.78e-120

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  4024 FPRDCGEEMQNGAGASRTSTIFLNGNReRPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNIS-GEFWLGN 4102
Cdd:pfam00147    1 FGRDCSDVYNKGAKTSGLYTIRPDGAT-KPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSpGEFWLGN 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  4103 EALHSLTQAGDYSMRVDLRAG-DEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGD-------SMSYHSGSVFSARDRDPN 4174
Cdd:pfam00147   80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 188528648  4175 SLLISCAVSYRGAWWYRNCHYANLNG--LYGSTVDHQ-GVSWYHWKGFEFSVPFTEMKLRPR 4233
Cdd:pfam00147  160 SPDGNCALSYGGGWWYNNCHAANLNGvyYYGGTYSKQnGIIWATWKGRWYSMKKAEMKIRPL 221

FBG

smart00186

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ...

4024-4233

1.72e-112

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.

Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 356.97 E-value: 1.72e-112

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   4024 FPRDCGEEMQNGAGASRTSTIFLNGNReRPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNE 4103
Cdd:smart00186    1 LPRDCSDVLQNGGKTSGLYTIYPDGSS-RPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   4104 ALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGD-SMSYHSGSVFSARDRDPNSLLISCA 4181
Cdd:smart00186   80 NIHLLTSQGKYELRIDLEdWEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159

                           170       180       190       200       210
                    ....*....|....*....|....*....|....*....|....*....|...
gi 188528648   4182 VSYRGAWWYRNCHYANLNGLYGS-TVDHQGVSWYHWKGFEFSVPFTEMKLRPR 4233
Cdd:smart00186  160 EEYGGGWWYNNCHAANLNGRYYPnNNYDNGINWATWKGSWYSLKFTEMKIRPL 212

FReD

cd00087

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...

4023-4233

5.53e-110

Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 350.00 E-value: 5.53e-110

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 4023 PFPRDCGEEMQNGAGASRTSTIFLNGNReRPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGN 4102
Cdd:cd00087     1 PLPRDCSEVLQRGGRTSGVYTIQPPGSN-EPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 4103 EALHSLTQAGDYSMRVDLR-AGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCA 4181
Cdd:cd00087    80 EKIHLLTSQGPYELRIDLEdWEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648 4182 VSYRGAWWYRNCHYANLNGLYGSTVDHQ----GVSWYHWKGFEFSVPFTEMKLRPR 4233
Cdd:cd00087   160 ESYSGGWWYNSCHASNLNGRYYSGGHRNeydnGINWATWKGSTYSLKFTEMKIRPK 215

FN3

Fibronectin type 3 domain [General function prediction only];

3135-3513

2.20e-13

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 76.58 E-value: 2.20e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3135 VGPVSAIGVTEEETPSPTEPSTeAPEAPEEPLLGELTVTGSSPDSLSLSWTVP-QGRFDSFTVQYKDRDGQPQVVRVRGE 3213
Cdd:COG3401    23 VNALSKAGGSGKTILVYLAVVL-SVTTKESPGTLLVAAGLSSGGGLGTGGRAGtTSGVAAVAVAAAPPTATGLTTLTGSG 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3214 ESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQgPFDSFLVQ 3293
Cdd:COG3401   102 SVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSP-DTSATAAV 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3294 YRDAQGQPQAVPVSGDLRavavsgLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGeLTVTDATPDSVGLSW 3373
Cdd:COG3401   181 ATTSLTVTSTTLVDGGGD------IEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTG-LTATADTPGSVTLSW 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3374 T-VPEGEFDSFVVQYK-DKDGRLQVVpVAANQREVTVQGLEPSRKYRFLLYGLSGRkrlGPISADSTTAPLEKELPPHL- 3450
Cdd:COG3401   254 DpVTESDATGYRVYRSnSGDGPFTKV-ATVTTTSYTDTGLTNGTTYYYRVTAVDAA---GNESAPSNVVSVTTDLTPPAa 329

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 188528648 3451 -GELTVAEETSSSLRLSWT-VAQGPFDSFVVqYRDT--DGQPRAVPVAADQRTVTVEDLEPGKKYKF 3513
Cdd:COG3401   330 pSGLTATAVGSSSITLSWTaSSDADVTGYNV-YRSTsgGGTYTKIAETVTTTSYTDTGLTPGTTYYY 395

fn3

Fibronectin type III domain;

3756-3834

6.42e-13

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 67.05 E-value: 6.42e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3756 SPRDLQFSEIRETSAKVNWMPPPSRA---DSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEE 3831
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGNgpiTGYEVEYRPKNSGEPwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 188528648  3832 SEP 3834
Cdd:pfam00041   82 GPP 84

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3757-3836

3.95e-12

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 64.83 E-value: 3.95e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3757 PRDLQFSEIRETSAKVNWMPPP---SRADSFKVSYQLADGGEPQSVQVDGQARTQ-KLQGLIPGARYEVTVVSVRGFEES 3832
Cdd:cd00063     4 PTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSyTLTGLKPGTEYEFRVRAVNGGGES 83


                  ....
gi 188528648 3833 EPLT 3836
Cdd:cd00063    84 PPSE 87

fn3

Fibronectin type III domain;

1988-2061

6.35e-12

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.97 E-value: 6.35e-12

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  1988 PRLGELTVTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGG 2061
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3

Fibronectin type 3 domain [General function prediction only];

1426-1801

9.52e-12

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 71.19 E-value: 9.52e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1426 TVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQqeeTPPATESPLeprlgelTVTDVTPNSVGLSWT-VPEGQFDSF 1504
Cdd:COG3401   195 GGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPT---TPPSAPTGL-------TATADTPGSVTLSWDpVTESDATGY 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1505 IVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYkmnMYGL----HDGqrmgplsvvIVTAPLPPAPATEASKPPLEPRl 1580
Cdd:COG3401   265 RVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTY---YYRVtavdAAG---------NESAPSNVVSVTTDLTPPAAPS- 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1581 gELTVTDITPDSVGLSWT-VPEGEFDSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVS 1658
Cdd:COG3401   332 -GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGNESAPS 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1659 VEA---KTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPegqfDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGR 1735
Cdd:COG3401   411 EEVsatTASAASGESLTASVDAVPLTDVAGATAAASAASNPG----VSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTT 486

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648 1736 KYRFLLYGLLGKKR--HGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEG 1801
Cdd:COG3401   487 ANLSVTTGSLVGGSgaSSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLT 554

fn3

Fibronectin type III domain;

2304-2377

1.19e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 1.19e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  2304 PRLEELTVTDATPDSLSLSWTVPE---GQFDHFLVQYKNGDGQPKAT--RVPGHEDRVTISGLEPDNKYKMNLYGFHGG 2377
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNeiTVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2843-2923

1.22e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 1.22e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  2843 PRLGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQ--PKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2917
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*.
gi 188528648  2918 rVGPIS 2923
Cdd:pfam00041   81 -EGPPS 85

fn3

Fibronectin type III domain;

2629-2709

2.24e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.24e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  2629 PRLGELTMTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2703
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*.
gi 188528648  2704 rVGPIS 2709
Cdd:pfam00041   81 -EGPPS 85

fn3

Fibronectin type III domain;

3059-3132

2.51e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.51e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648  3059 PRLGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 3132
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

3352-3434

2.54e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.54e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3352 PSPRlgELTVTDATPDSVGLSWTVPE---GEFDSFVVQYKDKDG--RLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSG 3426
Cdd:pfam00041    1 SAPS--NLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78


                   ....*...
gi 188528648  3427 rKRLGPIS 3434
Cdd:pfam00041   79 -GGEGPPS 85

fn3

Fibronectin type III domain;

1061-1141

2.61e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 2.61e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1061 GPPRlgELTVTDRTSDSLLLRWTVPE---GEFDSFVIQYKDRDGQ--PQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVG 1135
Cdd:pfam00041    1 SAPS--NLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78


                   ....*.
gi 188528648  1136 KKRHGP 1141
Cdd:pfam00041   79 GGEGPP 84

fn3

Fibronectin type III domain;

1265-1342

5.48e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 5.48e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1265 GELTVTGVTPDSLRLSWT---VAQGPFDSFMVQYKDAQGQ--PQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGrQRVG 1339
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG-GGEG 82


                   ...
gi 188528648  1340 PES 1342
Cdd:pfam00041   83 PPS 85

fn3

Fibronectin type III domain;

2198-2268

6.35e-11

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 6.35e-11

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2198 GQMTVRDITSDSLSLSWTVPE---GQFDHFLVQFKNGDGQ--PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 2268
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

843-919

1.27e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 60.51 E-value: 1.27e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   843 PQDLRVVAVTPTTLELGWLRP---QAEVDRFVVSYVSAGNQRVRLE--VPPEADGTLLTDLMPGVEYVVTVTAERGRAVS 917
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEitVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82


                   ..
gi 188528648   918 YP 919
Cdd:pfam00041   83 PP 84

fn3

Fibronectin type III domain;

1578-1643

1.46e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 60.12 E-value: 1.46e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 188528648  1578 PRLGELTVTDITPDSVGLSWTVPE---GEFDSFVVQYKDRDGQ--PQVVPVAADQREVTIPDLEPSRKYKF 1643
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEV 71

fn3

Fibronectin type III domain;

3168-3238

1.84e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 60.12 E-value: 1.84e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  3168 GELTVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDGQ--PQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEG 3238
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2526-2596

2.83e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 2.83e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2526 GELTVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEG 2596
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

2099-2169

3.43e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 3.43e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  2099 GELTVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEG 2169
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

1475-1555

3.90e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.97 E-value: 3.90e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1475 PRLGELTVTDVTPNSVGLSWTVPE---GQFDSFIVQYKDKDGQ--PQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQ 1549
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*.
gi 188528648  1550 RmGPLS 1555
Cdd:pfam00041   81 E-GPPS 85

fn3

Fibronectin type III domain;

3451-3513

4.05e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.97 E-value: 4.05e-10

                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648  3451 GELTVAEETSSSLRLSWT---VAQGPFDSFVVQYRDTDGQ--PRAVPVAADQRTVTVEDLEPGKKYKF 3513
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEV 71

fn3

Fibronectin type III domain;

2743-2810

4.79e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.97 E-value: 4.79e-10

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2743 TVTGSSPDSLSLSWTIP---QGHFDSFTVQYKDRDG--RPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEG 2810
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

3560-3635

5.70e-10

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.58 E-value: 5.70e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3560 LTVTDTTPDSMRLSWS---VAQGPFDSFVVQYEDTNGQ--PQALLVDGDQSKILISGLEPSTPYRFLLYGLHeGKRLGPL 3634
Cdd:pfam00041    6 LTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVN-GGGEGPP 84


                   .
gi 188528648  3635 S 3635
Cdd:pfam00041   85 S 85

FN3

Fibronectin type 3 domain [General function prediction only];

2418-2648

5.86e-10

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 65.41 E-value: 5.86e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2418 TVTGSSPDSLSLSWT-VPQGRFDSFTVqYKDRDGRPQVVRVGGE-ESEVTVGGLEPGRKYKmhlYglhegrRVGPVSTVG 2495
Cdd:COG3401   240 TATADTPGSVTLSWDpVTESDATGYRV-YRSNSGDGPFTKVATVtTTSYTDTGLTNGTTYY---Y------RVTAVDAAG 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2496 VTAPqedvdetPSPTEPGTEAPGPPEEPLlgELTVTGSSPDSLSLSWT-VPQGRFDSFTVQYKDR-DGRPQAVRVGGQES 2573
Cdd:COG3401   310 NESA-------PSNVVSVTTDLTPPAAPS--GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTT 380

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648 2574 KVTVRGLEPGRKYKmhlYGlhegrrlgpVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSW 2648
Cdd:COG3401   381 SYTDTGLTPGTTYY---YK---------VTAVDAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATA 443

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1156-1238

8.33e-10

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 58.28 E-value: 8.33e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1156 PGTPphlGNLWVTDPTPDSLHLSWTVPE---GQFDTFMVQYRDRDGRP--QVVPVEGPERSFVVSSLDPDHKYRFTLFGI 1230
Cdd:cd00063     1 PSPP---TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77


                  ....*...
gi 188528648 1231 aNKKRYGP 1238
Cdd:cd00063    78 -NGGGESP 84

fn3

Fibronectin type III domain;

2418-2485

1.51e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.42 E-value: 1.51e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2418 TVTGSSPDSLSLSWTVP---QGRFDSFTVQYKDRDG--RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEG 2485
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

fn3

Fibronectin type III domain;

762-831

1.61e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.42 E-value: 1.61e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648   762 ETTVRTEWTPAP---GPVDAYEIQFIPTTEGaSPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLP 831
Cdd:pfam00041   13 STSLTVSWTPPPdgnGPITGYEVEYRPKNSG-EPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1062-1131

2.12e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 57.12 E-value: 2.12e-09

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648 1062 PPRLGELTVTDRTSDSLLLRWTVPE---GEFDSFVIQYKDRDGQP--QVVPVEGPQRSAVITSLDPGRKYKFVLY 1131
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1575-1663

2.82e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 2.82e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1575 PLEPRlgELTVTDITPDSVGLSWTVPE---GEFDSFVVQYKDRDGQP--QVVPVAADQREVTIPDLEPSRKYKFLLFGIq 1649
Cdd:cd00063     1 PSPPT--NLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV- 77

                          90
                  ....*....|....*.
gi 188528648 1650 DGKRRSPVS--VEAKT 1663
Cdd:cd00063    78 NGGGESPPSesVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1156-1227

3.38e-09

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 56.47 E-value: 3.38e-09

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 188528648   1156 PGTPPhlgNLWVTDPTPDSLHLSWTVPE-----GQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTL 1227
Cdd:smart00060    1 PSPPS---NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRV 74

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1472-1560

3.39e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 3.39e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1472 PLEPRlgELTVTDVTPNSVGLSWTVPE---GQFDSFIVQYKDKDGQP--QVVPVAADQREVTVYNLEPERKYKMNMYGLH 1546
Cdd:cd00063     1 PSPPT--NLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....
gi 188528648 1547 DGQRMGPLSVVIVT 1560
Cdd:cd00063    79 GGGESPPSESVTVT 92

fn3

Fibronectin type III domain;

2957-3024

3.57e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 56.27 E-value: 3.57e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648  2957 TVTGSSPDSLSLSWTIP---QGRFDSFTVQYKDRDG--RPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEG 3024
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3

Fibronectin type 3 domain [General function prediction only];

1223-1496

3.89e-09

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 62.71 E-value: 3.89e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1223 YRFTLFGIANKKRYGP--LTADGTTAPErkeePPrpefleqpllGELTVTGVTPDSLRLSWT-VAQGPFDSFMVQYKDAQ 1299
Cdd:COG3401   207 YRVAATDTGGESAPSNevSVTTPTTPPS----AP----------TGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSG 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1300 GQPQAVPVAGDENEVTVPGLDPDRKYKmnlYGLRGRQRVGPESvvaktapqedvdeTPSPTELGTEAPESPEEPLlgELT 1379
Cdd:COG3401   273 DGPFTKVATVTTTSYTDTGLTNGTTYY---YRVTAVDAAGNES-------------APSNVVSVTTDLTPPAAPS--GLT 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1380 VTGSSPDSLSLFWT-VPQGSFDSFTVQYKDR-DGRPRAVRVGGKESEVTVGGLEPGHKYK-----MHLYGLhEGQRVGPV 1452
Cdd:COG3401   335 ATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVTTTSYTDTGLTPGTTYYykvtaVDAAGN-ESAPSEEV 413

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 188528648 1453 SAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTV 1496
Cdd:COG3401   414 SATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAV 457

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3159-3250

4.29e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.35 E-value: 4.29e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3159 PEAPEEpllgeLTVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGQP--QVVRVRGEESEVTVGGLEPGRKYKMHLY 3233
Cdd:cd00063     1 PSPPTN-----LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 3234 GLHEGQRVGPVSTVGIT 3250
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3359-3438

5.31e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 55.97 E-value: 5.31e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3359 LTVTDATPDSVGLSWTVPE---GEFDSFVVQYKDKDGR--LQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRlGPI 3433
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE-SPP 85


                  ....*
gi 188528648 3434 SADST 3438
Cdd:cd00063    86 SESVT 90

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1061-1128

6.25e-09

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 55.70 E-value: 6.25e-09

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648   1061 GPPRlgELTVTDRTSDSLLLRWTVPE-----GEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKF 1128
Cdd:smart00060    2 SPPS--NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

fn3

Fibronectin type III domain;

3933-4010

7.22e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 55.50 E-value: 7.22e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3933 APRDLEAKEVTPRTALLTWTEPPVRPA---GYLLSFHTPGGQN--QEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSL 4007
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGNGpitGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 188528648  4008 LPP 4010
Cdd:pfam00041   82 GPP 84

fn3

Fibronectin type III domain;

1672-1739

8.36e-09

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 55.11 E-value: 8.36e-09

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648  1672 GAPPRLGelwVTDPTPDSLRLSWTVPE---GQFDSFVVQFKDKDGPQV---VPVEGHERSVTVTPLDAGRKYRF 1739
Cdd:pfam00041    1 SAPSNLT---VTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPwneITVPGTTTSVTLTGLKPGTEYEV 71

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

841-921

8.65e-09

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 55.58 E-value: 8.65e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  841 DGPQDLRVVAVTPTTLELGWLRPQ---AEVDRFVVSYVSAGNQRVRLEVPPEADGT--LLTDLMPGVEYVVTVTAERGRA 915
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETsyTLTGLKPGTEYEFRVRAVNGGG 81


                  ....*.
gi 188528648  916 VSYPAS 921
Cdd:cd00063    82 ESPPSE 87

fn3

Fibronectin type III domain;

1163-1240

1.35e-08

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.73 E-value: 1.35e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1163 GNLWVTDPTPDSLHLSWTVPE---GQFDTFMVQYRDRDG--RPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIaNKKRYG 1237
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV-NGGGEG 82


                   ...
gi 188528648  1238 PLT 1240
Cdd:pfam00041   83 PPS 85

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2837-2928

1.42e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 54.81 E-value: 1.42e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2837 PEPPnkprlGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQP--KVVRVPGHEDGVTISGLEPDHKYKMNLY 2911
Cdd:cd00063     1 PSPP-----TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 2912 GFHGGQRVGPISVIGVT 2928
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1575-1643

1.71e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.16 E-value: 1.71e-08

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648   1575 PLEPRlgELTVTDITPDSVGLSWTVPE-----GEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKF 1643
Cdd:smart00060    1 PSPPS--NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

fn3

Fibronectin type III domain;

3654-3736

1.88e-08

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.34 E-value: 1.88e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  3654 PRLSQLSVTDVTTSSLRLNWEAPP---GAFDSFLLRFgvpSPSTLEPHPRpllqrELMVPGTRHSAVLRDLRSGTLYSLT 3730
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEY---RPKNSGEPWN-----EITVPGTTTSVTLTGLKPGTEYEVR 72


                   ....*.
gi 188528648  3731 LYGLRG 3736
Cdd:pfam00041   73 VQAVNG 78

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3359-3419

2.02e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.16 E-value: 2.02e-08

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648   3359 LTVTDATPDSVGLSWTVPE-----GEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRF 3419
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2307-2389

2.63e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 54.04 E-value: 2.63e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2307 EELTVTDATPDSLSLSWTVPE---GQFDHFLVQYKNGDGQP--KATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVG 2381
Cdd:cd00063     5 TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESP 84


                  ....*...
gi 188528648 2382 PVSAIGVT 2389
Cdd:cd00063    85 PSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3756-3832

2.95e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 2.95e-08

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   3756 SPRDLQFSEIRETSAKVNWMPPPS-RADSFKVSYQLADGGEP---QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEE 3831
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPDdGITGYIVGYRVEYREEGsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGE 82


                    .
gi 188528648   3832 S 3832
Cdd:smart00060   83 G 83

FN3

Fibronectin type 3 domain [General function prediction only];

763-948

3.54e-08

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 59.63 E-value: 3.54e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  763 TTVRTEWTPAPGP-VDAYEIQFIPTTEGaspPFTARVPSSASAYDQRGLAPGQEYQVTVRALRG---TSWGLPASKTITT 838
Cdd:COG3401   247 GSVTLSWDPVTESdATGYRVYRSNSGDG---PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAagnESAPSNVVSVTTD 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  839 MI--DGPQDLRVVAVTPTTLELGW-LRPQAEVDRFVVsYVSAGNQRVRLEVPPEADGTLLTD--LMPGVEYVVTVTA--E 911
Cdd:COG3401   324 LTppAAPSGLTATAVGSSSITLSWtASSDADVTGYNV-YRSTSGGGTYTKIAETVTTTSYTDtgLTPGTTYYYKVTAvdA 402

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 188528648  912 RGRAVSYPASVRANTGSSPLGllGTTDEPPPSGPSTT 948
Cdd:COG3401   403 AGNESAPSEEVSATTASAASG--ESLTASVDAVPLTD 437

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1993-2073

3.59e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.65 E-value: 3.59e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1993 LTVTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQP--KAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPV 2067
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPS 86


                  ....*.
gi 188528648 2068 SVVGVT 2073
Cdd:cd00063    87 ESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

841-914

4.12e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.39 E-value: 4.12e-08

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648    841 DGPQDLRVVAVTPTTLELGWLRPQAE-----VDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGR 914
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80

FN3

Fibronectin type 3 domain [General function prediction only];

1105-1426

4.13e-08

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 59.63 E-value: 4.13e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1105 VVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRhGPLVAEAKILPQSDPsPGTPphlGNLWVTDPTPDSLHLSWT-VPE 1183
Cdd:COG3401   184 SLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGE-SAPSNEVSVTTPTTP-PSAP---TGLTATADTPGSVTLSWDpVTE 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1184 GQFDTFMVqYRDRDGRPQVVPV-EGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPL--TADGTTAPERkeePPRPEFle 1260
Cdd:COG3401   259 SDATGYRV-YRSNSGDGPFTKVaTVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPsnVVSVTTDLTP---PAAPSG-- 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1261 qpllgeLTVTGVTPDSLRLSWT-VAQGPFDSFMVQYKDAQ-GQPQAVPVAGDENEVTVPGLDPDRKYKmnlYGLRGRQRV 1338
Cdd:COG3401   333 ------LTATAVGSSSITLSWTaSSDADVTGYNVYRSTSGgGTYTKIAETVTTTSYTDTGLTPGTTYY---YKVTAVDAA 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1339 GPESvvaktAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRV 1418
Cdd:COG3401   404 GNES-----APSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVT 478


                  ....*...
gi 188528648 1419 GGKESEVT 1426
Cdd:COG3401   479 ATTTDTTT 486

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1671-1739

4.45e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.65 E-value: 4.45e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648 1671 PGAPprlGELWVTDPTPDSLRLSWTVPE---GQFDSFVVQFKDKDGPQVVPVE---GHERSVTVTPLDAGRKYRF 1739
Cdd:cd00063     1 PSPP---TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEvtpGSETSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3053-3144

4.59e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 4.59e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3053 PEPPikprlGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQP--KAVRVPGHEDGVTISGLEPDHKYKMNLY 3127
Cdd:cd00063     1 PSPP-----TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 3128 GFHGGQRVGPVSAIGVT 3144
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2517-2591

5.80e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 5.80e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2517 PGPPEEpllgeLTVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGRP--QAVRVGGQESKVTVRGLEPGRKYKMHLY 2591
Cdd:cd00063     1 PSPPTN-----LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2101-2181

5.97e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 5.97e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2101 LTVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPV 2175
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPS 86


                  ....*.
gi 188528648 2176 SAVGVT 2181
Cdd:cd00063    87 ESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2517-2591

7.62e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 52.62 E-value: 7.62e-08

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2517 PGPPEEpllgeLTVTGSSPDSLSLSWTVPQ-----GRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLY 2591
Cdd:smart00060    1 PSPPSN-----LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3447-3513

8.24e-08

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 52.23 E-value: 8.24e-08

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 188528648   3447 PPHLGELTVAEETSSSLRLSWT-----VAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKF 3513
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3447-3513

8.32e-08

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 52.88 E-value: 8.32e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 188528648 3447 PPHLGELTVAEETSSSLRLSWTVAQ---GPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKF 3513
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2418-2497

1.38e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 52.11 E-value: 1.38e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2418 TVTGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2492
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSE 87


                  ....*
gi 188528648 2493 TVGVT 2497
Cdd:cd00063    88 SVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2623-2714

1.44e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 52.11 E-value: 1.44e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2623 PEPPIKPRLgeltmTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQP--KAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
Cdd:cd00063     1 PSPPTNLRV-----TDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVR 75

                          90
                  ....*....|....*..
gi 188528648 2698 GFHGGQRVGPISVIGVT 2714
Cdd:cd00063    76 AVNGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1267-1347

1.65e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.73 E-value: 1.65e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1267 LTVTGVTPDSLRLSWTVAQ---GPFDSFMVQYKDAQGQP--QAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGP- 1340
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPs 86


                  ....*..
gi 188528648 1341 ESVVAKT 1347
Cdd:cd00063    87 ESVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3560-3639

2.10e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.73 E-value: 2.10e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3560 LTVTDTTPDSMRLSWSVAQ---GPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRlGPL 3634
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE-SPP 85


                  ....*
gi 188528648 3635 SAEGT 3639
Cdd:cd00063    86 SESVT 90

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2837-2911

2.88e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 50.69 E-value: 2.88e-07

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2837 PEPPnkprlGELTVTDATPDSLSLSWMVPE-----GQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLY 2911
Cdd:smart00060    1 PSPP-----SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

fn3

Fibronectin type III domain;

1376-1446

3.19e-07

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 50.88 E-value: 3.19e-07

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  1376 GELTVTGSSPDSLSLFWTVP---QGSFDSFTVQYKDRDG--RPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEG 1446
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1472-1539

3.43e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 50.69 E-value: 3.43e-07

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 188528648   1472 PLEPRlgELTVTDVTPNSVGLSWTVPE-----GQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYK 1539
Cdd:smart00060    1 PSPPS--NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYE 71

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3159-3233

3.75e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 50.69 E-value: 3.75e-07

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   3159 PEAPEEpllgeLTVTGSSPDSLSLSWTVPQ-----GRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLY 3233
Cdd:smart00060    1 PSPPSN-----LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3560-3620

5.43e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 5.43e-07

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648   3560 LTVTDTTPDSMRLSWS-----VAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRF 3620
Cdd:smart00060    7 LRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain [General function prediction only];

1993-2191

5.55e-07

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 55.78 E-value: 5.55e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1993 LTVTDATPDSLSLSWT-VPEGQFDHFLVqYRNGDGQPKAVRV-PGHEEGVTISGLEPDHKYKmnlYgfhggqrmgpvSVV 2070
Cdd:COG3401   239 LTATADTPGSVTLSWDpVTESDATGYRV-YRSNSGDGPFTKVaTVTTTSYTDTGLTNGTTYY---Y-----------RVT 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2071 GVTAAEEE-TPSPT---EPSMEAPEPAEepllgELTVTGSSPDSLSLSWT-VPQGRFDSFTVQYKDR-DGRPQVVRVGGE 2144
Cdd:COG3401   304 AVDAAGNEsAPSNVvsvTTDLTPPAAPS-----GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVT 378

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 188528648 2145 ESEVTVGGLEPGRKYK-----MHLYGLhEGRRVGPVSAVGVTAPEEESPDAP 2191
Cdd:COG3401   379 TTSYTDTGLTPGTTYYykvtaVDAAGN-ESAPSEEVSATTASAASGESLTAS 429

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1671-1739

5.76e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 5.76e-07

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648   1671 PGAPPRLgelWVTDPTPDSLRLSWTVPE-GQFDSFVVQFKDKDGP-----QVVPVEGHERSVTVTPLDAGRKYRF 1739
Cdd:smart00060    1 PSPPSNL---RVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREegsewKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3053-3127

5.99e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 5.99e-07

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   3053 PEPPikprlGELTVTDATPDSLSLSWMVPE-----GQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 3127
Cdd:smart00060    1 PSPP-----SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain [General function prediction only];

3812-4002

5.99e-07

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 55.78 E-value: 5.99e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3812 GLIPGARYEVTVVSVRGFEESEPLTGFL----TTVPDGPTQLRALNLTEGFAVLHWKPPQNP-VDTYDVQVTAPGAPPLQ 3886
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSvttpTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFT 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3887 AETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS--ITFTTGLE---APRDLEAKEVTPRTALLTWTEPP-VRPAG 3960
Cdd:COG3401   278 KVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSnvVSVTTDLTppaAPSGLTATAVGSSSITLSWTASSdADVTG 357

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 188528648 3961 YLL-SFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAM 4002
Cdd:COG3401   358 YNVyRSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAV 400

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2101-2164

6.05e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 6.05e-07

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   2101 LTVTGSSPDSLSLSWTVPQ-----GRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2164
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2743-2822

7.61e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.80 E-value: 7.61e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2743 TVTGSSPDSLSLSWTIPQ---GHFDSFTVQYKDRDGRP--QVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSE 87


                  ....*
gi 188528648 2818 TVGVT 2822
Cdd:cd00063    88 SVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1773-1862

7.92e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.80 E-value: 7.92e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1773 PPKPRlgeELQVTTVTQNSVGLSWTVPE---GQFDSFVVQYKDRDGQP--QVVPVEGSLREVSVPGLDPAHRYKLLLYGL 1847
Cdd:cd00063     1 PSPPT---NLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*
gi 188528648 1848 HHGKRVGPISAVAIT 1862
Cdd:cd00063    78 NGGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2957-3036

8.15e-07

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.80 E-value: 8.15e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2957 TVTGSSPDSLSLSWTIPQ---GRFDSFTVQYKDRDGRP--QVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVS 3031
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSE 87


                  ....*
gi 188528648 3032 AVGVT 3036
Cdd:cd00063    88 SVTVT 92

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

311-337

8.92e-07

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 47.68 E-value: 8.92e-07

                           10        20
                   ....*....|....*....|....*..
gi 188528648   311 CPRGCSQRGRCKDGRCVCDPGYTGEDC 337
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1993-2056

9.58e-07

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.54 E-value: 9.58e-07

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   1993 LTVTDATPDSLSLSWTVPE-----GQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLY 2056
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

2188-2277

1.02e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.42 E-value: 1.02e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2188 PDAPlaklrlGQMTVRDITSDSLSLSWTVPE---GQFDHFLVQFKNGDGQP--KAVRVPGHEDGVTISGLEPDHKYKMNL 2262
Cdd:cd00063     1 PSPP------TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRV 74

                          90
                  ....*....|....*
gi 188528648 2263 YGFHGGQRVGPVSAV 2277
Cdd:cd00063    75 RAVNGGGESPPSESV 89

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3932-4017

1.03e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.42 E-value: 1.03e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3932 EAPRDLEAKEVTPRTALLTWTEPPVRPA---GYLLSFHTPGGQNQEILLPGGI--TSHQLLGLFPSTSYNARLQAM--WG 4004
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDGGpitGYVVEYREKGSGDWKEVEVTPGseTSYTLTGLKPGTEYEFRVRAVngGG 81

                          90
                  ....*....|...
gi 188528648 4005 QSlLPPVSTSFTT 4017
Cdd:cd00063    82 ES-PPSESVTVTT 93

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

373-399

1.09e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 47.68 E-value: 1.09e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   373 CPRDCRGRGRCEDGECICDTGYSGDDC 399
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1370-1458

1.28e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 49.42 E-value: 1.28e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1370 PEEPllGELTVTGSSPDSLSLFWTVPQ---GSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLH 1444
Cdd:cd00063     1 PSPP--TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....
gi 188528648 1445 EGQRVGPVSAVGVT 1458
Cdd:cd00063    79 GGGESPPSESVTVT 92

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3933-4001

1.31e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.15 E-value: 1.31e-06

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648   3933 APRDLEAKEVTPRTALLTWTEPPVRPA-----GYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQA 4001
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPDDGItgyivGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1267-1330

1.55e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 1.55e-06

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   1267 LTVTGVTPDSLRLSWT-----VAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLY 1330
Cdd:smart00060    7 LRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain [General function prediction only];

2566-2863

1.57e-06

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 54.24 E-value: 1.57e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2566 VRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTedeaettqaVPTMTPEPPikprlGELTMTDATPDSLS 2645
Cdd:COG3401   185 LTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVT---------TPTTPPSAP-----TGLTATADTPGSVT 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2646 LSWT-VPEGQFDHFLVqYRNGDGQPKAVRVpGHEDGVTI--SGLEPDHKYK-----MNLYGFHGGqrvgPISVIGVTAAE 2717
Cdd:COG3401   251 LSWDpVTESDATGYRV-YRSNSGDGPFTKV-ATVTTTSYtdTGLTNGTTYYyrvtaVDAAGNESA----PSNVVSVTTDL 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2718 EETPSPTELsteapeppeepllgelTVTGSSPDSLSLSWT-IPQGHFDSFTVQYKDRDGRP--QVMRVRGEESeVTVGGL 2794
Cdd:COG3401   325 TPPAAPSGL----------------TATAVGSSSITLSWTaSSDADVTGYNVYRSTSGGGTytKIAETVTTTS-YTDTGL 387

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648 2795 EPGRKYKmhlYglhegrRVGPVSTVGVTEDEAETTQAVPTTTPEPPNkprLGELTVTDATPDSLSLSWM 2863
Cdd:COG3401   388 TPGTTYY---Y------KVTAVDAAGNESAPSEEVSATTASAASGES---LTASVDAVPLTDVAGATAA 444

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2623-2697

1.58e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 1.58e-06

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2623 PEPPikprlGELTMTDATPDSLSLSWTVPE-----GQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
Cdd:smart00060    1 PSPP-----SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain [General function prediction only];

1068-1226

1.61e-06

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 54.24 E-value: 1.61e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1068 LTVTDRTSDSLLLRWT-VPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEA 1146
Cdd:COG3401   239 LTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSNVV 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 1147 KILPqsDPSPGTPPhlGNLWVTDPTPDSLHLSWT-VPEGQFDTFMVqYRD--RDGRPQVVPVEGPERSFVVSSLDPDHKY 1223
Cdd:COG3401   319 SVTT--DLTPPAAP--SGLTATAVGSSSITLSWTaSSDADVTGYNV-YRStsGGGTYTKIAETVTTTSYTDTGLTPGTTY 393


                  ...
gi 188528648 1224 RFT 1226
Cdd:COG3401   394 YYK 396

fn3

Fibronectin type III domain;

1774-1857

1.70e-06

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.57 E-value: 1.70e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  1774 PKPRlgeELQVTTVTQNSVGLSWTVPE---GQFDSFVVQYKDRDGQ--PQVVPVEGSLREVSVPGLDPAHRYKLLLYGlH 1848
Cdd:pfam00041    1 SAPS---NLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQA-V 76


                   ....*....
gi 188528648  1849 HGKRVGPIS 1857
Cdd:pfam00041   77 NGGGEGPPS 85

fn3

Fibronectin type III domain;

3261-3326

2.15e-06

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.57 E-value: 2.15e-06

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 188528648  3261 PRLGELAVAAVTSDSVGLSWT---VAQGPFDSFLVQYRDAQGQ--PQAVPVSGDLRAVAVSGLDPARKYKF 3326
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEV 71

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2418-2480

2.22e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.38 E-value: 2.22e-06

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648   2418 TVTGSSPDSLSLSWTVPQ-----GRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

fn3

Fibronectin type III domain;

1885-1955

2.30e-06

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.18 E-value: 2.30e-06

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  1885 GELTVEEATSHTLHLSWM---VTEGEFDSFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
Cdd:pfam00041    4 SNLTVTDVTSTSLTVSWTpppDGNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

249-275

2.33e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 46.52 E-value: 2.33e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   249 CPRGCSQRGRCEGGRCVCDPGYTGDDC 275
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

314-418

2.88e-06

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 49.76 E-value: 2.88e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  314 GCSQRG-RCKDGRCVC-----DPGYTGEDCGtrSCPWDCGEGGRCVDGRCVCWPGYT--GEDC-STRTCPRDCRGRGR-- 382
Cdd:NF041328   13 GCPEPGaVCPEGLSVCggacvDLRSDPSNCG--ACGVACGAGQTCVAGACGCGPGTVacGGACvDTASDPAHCGACGAac 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 188528648  383 -----CEDGEC--ICDTGYS--GDDC-GVRSCPGDCNQRG-RCEDGR 418
Cdd:NF041328   91 apgqvCEGGACreACSEGLTrcGGACvDLATDPLHCGACGvACDPGE 137

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

753-838

3.32e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 48.26 E-value: 3.32e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  753 EGMRMHLLEETTVRTEWTPAP---GPVDAYEIQFIPTTEGASPPFTARVPSSASaYDQRGLAPGQEYQVTVRALRGTSWG 829
Cdd:cd00063     5 TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETS-YTLTGLKPGTEYEFRVRAVNGGGES 83

                          90
                  ....*....|
gi 188528648  830 LPA-SKTITT 838
Cdd:cd00063    84 PPSeSVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2307-2372

3.38e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 47.99 E-value: 3.38e-06

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 188528648   2307 EELTVTDATPDSLSLSWTVPE-----GQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLY 2372
Cdd:smart00060    5 SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

559-585

3.45e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 46.14 E-value: 3.45e-06

                           10        20
                   ....*....|....*....|....*..
gi 188528648   559 CPGGCRGRGQCLDGRCVCEDGYSGEDC 585
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain [General function prediction only];

2790-3079

3.74e-06

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 53.08 E-value: 3.74e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2790 TVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTedeaettqaVPTTTPEPPnkprlGELTVTDATPDSLSLSW-MVPEGQ 2868
Cdd:COG3401   195 GGGDIEPGTTYYYRVAATDTGGESAPSNEVSVT---------TPTTPPSAP-----TGLTATADTPGSVTLSWdPVTESD 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2869 FDHFLVQYRNGDGQP--KVVRVPGHEdgVTISGLEPDHKYK-----MNLYGFHGGqrvgPISVIGVTAAEEETPAPTEPs 2941
Cdd:COG3401   261 ATGYRVYRSNSGDGPftKVATVTTTS--YTDTGLTNGTTYYyrvtaVDAAGNESA----PSNVVSVTTDLTPPAAPSGL- 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2942 teapeppeepllgelTVTGSSPDSLSLSWT-IPQGRFDSFTVQYKDRDGRP--QVVRVRGEESeVTVGGLEPGckyKMHL 3018
Cdd:COG3401   334 ---------------TATAVGSSSITLSWTaSSDADVTGYNVYRSTSGGGTytKIAETVTTTS-YTDTGLTPG---TTYY 394

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 188528648 3019 YglhegqRVGPVSAVGvtapkDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWM 3079
Cdd:COG3401   395 Y------KVTAVDAAG-----NESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAA 444

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2188-2263

6.77e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.84 E-value: 6.77e-06

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648   2188 PDAPlaklrlGQMTVRDITSDSLSLSWTVPE-----GQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 2262
Cdd:smart00060    1 PSPP------SNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRV 74


                    .
gi 188528648   2263 Y 2263
Cdd:smart00060   75 R 75

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3843-3929

7.33e-06

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 47.11 E-value: 7.33e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3843 PDGPTQLRALNLTEGFAVLHWKPPQN---PVDTYDVQVTAPGAPPLQ--AETPGSAVDYPLHDLVLHTNYTATVRGLRGP 3917
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEDdggPITGYVVEYREKGSGDWKevEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|...
gi 188528648 3918 NLTSPA-SITFTT 3929
Cdd:cd00063    81 GESPPSeSVTVTT 93

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2957-3019

7.39e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.84 E-value: 7.39e-06

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648   2957 TVTGSSPDSLSLSWTIPQ-----GRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLY 3019
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1773-1842

9.17e-06

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.45 E-value: 9.17e-06

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648   1773 PPKPRlgeELQVTTVTQNSVGLSWTVPE-----GQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKL 1842
Cdd:smart00060    1 PSPPS---NLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

2743-2805

1.04e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.45 E-value: 1.04e-05

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648   2743 TVTGSSPDSLSLSWTIPQ-----GHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLY 2805
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

PTZ00214

high cysteine membrane protein Group 4; Provisional

254-669

1.42e-05

high cysteine membrane protein Group 4; Provisional

Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 51.46 E-value: 1.42e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  254 SQRGRCEGGRCVCDPGYTGddcGMRSCPRGCSQRGRCENGRCvcNPGYTGEDCgvRSCPRGCSqrgrcKDGRCVCDPGYT 333
Cdd:PTZ00214  341 SKNDDNNGDGYLCGDATNG---GVSGCATCGYNSGAVTCTRC--SAGYLGVDG--KSCSESCS-----GDTRGVCTKVAE 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  334 GEDCGTRSCpwdcgeggrcvdgRCVCWPGYTGEDCSTRTCPRDCrgrGRCEDGE---C-ICDTGYSGDDCGVRSCPGDCN 409
Cdd:PTZ00214  409 GSESTEVSC-------------RCVCKPTFYNSSGTCTPCTDSC---AVCKDGTptgCqQCSPGKILEFSIVSSESADCV 472

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  410 QRgrcedgrcvCWPGYTGTDCG-----SRACPRDCRGRGRCENGVCVCNagySGEDCGVRSCPG----DCRGRGRCESGR 480
Cdd:PTZ00214  473 DQ---------CSVGSECAECGitidgSRYCTRCKDASTYPFNGVCIPN---TQRDAYCTSTANgactTCSGAAFLMNGG 540

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  481 CMCWPGYTGRDCGTRACPGDC----RGRGRCVDGRCV-CNP---GFTGEDCGS-RRCPGDC---RGHGlCEDGVCV---- 544
Cdd:PTZ00214  541 CYTTEHYPGSTICDKQSNGKCtttkKGYGISPDGKLLeCDPtclACTAPGPGRcTRCPSDKllkRASG-AATGSCVdpga 619

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  545 CDAGY--SGEDCSTRSCPGgCRGRG------QCLDGRCVCEDGYSgedcgvrqCPNDCSQHGVCQD---GVCICW--EGY 611
Cdd:PTZ00214  620 CVDGYyaDGDACLPCATPG-CKTCGhasfctECAGELFVSLDGQS--------CLEECTGDKVVGEvsgGVRRCWceRGF 690

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648  612 V----SEDCSIRT-CPSNCHGRGRCEE-GRCL-CDPGYTGPTCATRMCPADCRGRGRCVQGVCLC 669
Cdd:PTZ00214  691 LpaldRSGCVLPTeCPPDMPSCAACDEsGRCLlCVTSGHNVQVDQRTCAEGCGARASSNQGVCMC 755

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

280-306

1.69e-05

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 44.21 E-value: 1.69e-05

                           10        20
                   ....*....|....*....|....*..
gi 188528648   280 CPRGCSQRGRCENGRCVCNPGYTGEDC 306
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1378-1441

1.73e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 45.68 E-value: 1.73e-05

                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648   1378 LTVTGSSPDSLSLFWTVPQGS-----FDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLY 1441
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

fn3

Fibronectin type III domain;

3846-3916

2.55e-05

Fibronectin type III domain;

Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 45.48 E-value: 2.55e-05

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 188528648  3846 PTQLRALNLTEGFAVLHWKPP---QNPVDTYDVQVTAPGAPPLQAE--TPGSAVDYPLHDLVLHTNYTATVRGLRG 3916
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEPWNEitVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

528-555

2.73e-05

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 43.44 E-value: 2.73e-05

                           10        20
                   ....*....|....*....|....*...
gi 188528648   528 CPGDCRGHGLCEDGVCVCDAGYSGEDCS 555
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3657-3732

3.68e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.91 E-value: 3.68e-05

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 188528648   3657 SQLSVTDVTTSSLRLNWEAPPGA-FDSFLLRFgvpspsTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLY 3732
Cdd:smart00060    5 SNLRVTDVTSTSVTLSWEPPPDDgITGYIVGY------RVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

244-356

5.30e-05

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 46.29 E-value: 5.30e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  244 CSQRS--CPRGCSqrgRCeGGRCVcdpGYTGD--DCGmrSCPRGCSQRGRCENGRCVCNPGytGEDCG-----VRSCPRG 314
Cdd:NF041328   14 CPEPGavCPEGLS---VC-GGACV---DLRSDpsNCG--ACGVACGAGQTCVAGACGCGPG--TVACGgacvdTASDPAH 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648  315 CSQRGR-------CKDGRC--VCDPGYTgeDCGtRSC------PWDCGE-GGRCVDGR 356
Cdd:NF041328   83 CGACGAacapgqvCEGGACreACSEGLT--RCG-GACvdlatdPLHCGAcGVACDPGE 137

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

625-647

6.61e-05

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 42.33 E-value: 6.61e-05

                           10        20
                   ....*....|....*....|....*
gi 188528648   625 CHGRGRCE--EGRCLCDPGYTGPTC 647
Cdd:pfam07974    2 CSGRGTCVnqCGKCVCDSGYQGATC 26

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3843-3912

9.14e-05

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 43.76 E-value: 9.14e-05

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 188528648   3843 PDGPTQLRALNLTEGFAVLHWKPPQNP-----VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 3912
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75

FN3

Fibronectin type 3 domain [General function prediction only];

2309-2533

9.88e-05

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 48.46 E-value: 9.88e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2309 LTVTDATPDSLSLSWT-VPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYK-----MNLYGFHGgqrvGP 2382
Cdd:COG3401   239 LTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYyrvtaVDAAGNES----AP 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 2383 VSAIGVTAAEEETPSPTepsmeapeppeepllgELTVTGSSPDSLSLSWT-VPQGRFDSFTVQYKDR-DGRPQVVRVGGE 2460
Cdd:COG3401   315 SNVVSVTTDLTPPAAPS----------------GLTATAVGSSSITLSWTaSSDADVTGYNVYRSTSgGGTYTKIAETVT 378

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648 2461 ESEVTVGGLEPGRKYK-----MHLYGLhEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGS 2533
Cdd:COG3401   379 TTSYTDTGLTPGTTYYykvtaVDAAGN-ESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSA 455

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

253-275

1.21e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 41.56 E-value: 1.21e-04

                           10        20
                   ....*....|....*....|....*
gi 188528648   253 CSQRGRCE--GGRCVCDPGYTGDDC 275
Cdd:pfam07974    2 CSGRGTCVnqCGKCVCDSGYQGATC 26

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

497-523

1.22e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 41.90 E-value: 1.22e-04

                           10        20
                   ....*....|....*....|....*..
gi 188528648   497 CPGDCRGRGRCVDGRCVCNPGFTGEDC 523
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

1887-1955

1.39e-04

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 43.37 E-value: 1.39e-04

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648   1887 LTVEEATSHTLHLSWM-----VTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
Cdd:smart00060    7 LRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

500-523

1.63e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 41.18 E-value: 1.63e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   500 DCRGRGRCVD--GRCVCNPGFTGEDC 523
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

191-295

2.18e-04

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 44.36 E-value: 2.18e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  191 CNDQGRCVRGRCVCFPGYTgpSCGwpscpgdcqgrGRCVQ--------GVC--VCRAGFSgpdCSQRSCPRGCSQ-RGRC 259
Cdd:NF041328   49 CGAGQTCVAGACGCGPGTV--ACG-----------GACVDtasdpahcGACgaACAPGQV---CEGGACREACSEgLTRC 112

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 188528648  260 eGGRCV---CDPGYTGdDCGmRSCPRGCSqrgrCENGRC 295
Cdd:NF041328  113 -GGACVdlaTDPLHCG-ACG-VACDPGES----CRGGAC 144

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

1887-1955

2.41e-04

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 42.87 E-value: 2.41e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648 1887 LTVEEATSHTLHLSWMV---TEGEFDSFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPpedDGGPITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

221-244

2.96e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 40.41 E-value: 2.96e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   221 DCQGRGRCVQ--GVCVCRAGFSGPDC 244
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

284-306

3.08e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 40.41 E-value: 3.08e-04

                           10        20
                   ....*....|....*....|....*
gi 188528648   284 CSQRGRCEN--GRCVCNPGYTGEDC 306
Cdd:pfam07974    2 CSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

342-369

3.29e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 40.74 E-value: 3.29e-04

                           10        20
                   ....*....|....*....|....*...
gi 188528648   342 CPWDCGEGGRCVDGRCVCWPGYTGEDCS 369
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29

PTZ00214

high cysteine membrane protein Group 4; Provisional

251-577

3.43e-04

high cysteine membrane protein Group 4; Provisional

Pssm-ID: 173479 [Multi-domain] Cd Length: 800 Bit Score: 46.83 E-value: 3.43e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  251 RGCSQRGRCEGG-RCV-CDPGYTGDDCgmRSCPRGCS--QRGRCE-----------NGRCVCNPGYTGEDCGVRSCPRGC 315
Cdd:PTZ00214  362 SGCATCGYNSGAvTCTrCSAGYLGVDG--KSCSESCSgdTRGVCTkvaegsestevSCRCVCKPTFYNSSGTCTPCTDSC 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  316 SQrgrCKDGR---C-VCDPGYTGE---------DCGTR-SCPWDCGEGGRCVDG-----RC----------VCWPGyTGE 366
Cdd:PTZ00214  440 AV---CKDGTptgCqQCSPGKILEfsivssesaDCVDQcSVGSECAECGITIDGsryctRCkdastypfngVCIPN-TQR 515

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  367 D--CSTR---TCPRdCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQR----GRCEDGRCV-CWPgyTGTDCGSRA-- 434
Cdd:PTZ00214  516 DayCTSTangACTT-CSGAAFLMNGGCYTTEHYPGSTICDKQSNGKCTTTkkgyGISPDGKLLeCDP--TCLACTAPGpg 592

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  435 ----CPRDC---RGRGrCENGVCV----CNAGY--SGEDCGVRSCPGdCRGRGrcESGRCMCWPGYTGRDCGTRACPGDC 501
Cdd:PTZ00214  593 rctrCPSDKllkRASG-AATGSCVdpgaCVDGYyaDGDACLPCATPG-CKTCG--HASFCTECAGELFVSLDGQSCLEEC 668

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  502 RGR---GRCVDG--RCVCNPGF-----TGEDCGSRRCPGDCRGHGLC-EDGVCV-CDAGYSGEDCSTRSCPGGCRGRGQC 569
Cdd:PTZ00214  669 TGDkvvGEVSGGvrRCWCERGFlpaldRSGCVLPTECPPDMPSCAACdESGRCLlCVTSGHNVQVDQRTCAEGCGARASS 748


                  ....*...
gi 188528648  570 LDGRCVCE 577
Cdd:PTZ00214  749 NQGVCMCE 756

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3657-3732

3.53e-04

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 42.48 E-value: 3.53e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648 3657 SQLSVTDVTTSSLRLNWEAPP---GAFDSFLLRFGVPSPSTLEPHPRPllqrelmvPGTRHSAVLRDLRSGTLYSLTLY 3732
Cdd:cd00063     5 TNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVT--------PGSETSYTLTGLKPGTEYEFRVR 75

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

438-461

3.78e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 40.41 E-value: 3.78e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   438 DCRGRGRCEN--GVCVCNAGYSGEDC 461
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

407-430

3.82e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 40.41 E-value: 3.82e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   407 DCNQRGRCED--GRCVCWPGYTGTDC 430
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

376-399

4.09e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 40.02 E-value: 4.09e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   376 DCRGRGRCED--GECICDTGYSGDDC 399
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

469-492

4.43e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 40.02 E-value: 4.43e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   469 DCRGRGRCES--GRCMCWPGYTGRDC 492
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

435-461

4.88e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.97 E-value: 4.88e-04

                           10        20
                   ....*....|....*....|....*..
gi 188528648   435 CPRDCRGRGRCENGVCVCNAGYSGEDC 461
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...

3266-3346

6.16e-04

Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 41.71 E-value: 6.16e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3266 LAVAAVTSDSVGLSWTVAQ---GPFDSFLVQYRDAQGQP--QAVPVSGDLRAVAVSGLDPARKYKFLLFGlQNGKRHGP- 3339
Cdd:cd00063     7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwkEVEVTPGSETSYTLTGLKPGTEYEFRVRA-VNGGGESPp 85


                  ....*...
gi 188528648 3340 -VPVEART 3346
Cdd:cd00063    86 sESVTVTT 93

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

190-213

6.37e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 39.64 E-value: 6.37e-04

                           10        20
                   ....*....|....*....|....*.
gi 188528648   190 DCNDQGRCVR--GRCVCFPGYTGPSC 213
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

571-703

7.41e-04

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 42.82 E-value: 7.41e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  571 DGRCVCEDGySGEDCGVrqCPNDCSQHGVCQDGVCICWEGYVS--EDC-SIRTCPSNCHGRG-RCEEGRclcdpgytgpT 646
Cdd:NF041328   29 GGACVDLRS-DPSNCGA--CGVACGAGQTCVAGACGCGPGTVAcgGACvDTASDPAHCGACGaACAPGQ----------V 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 188528648  647 CATRMCPADC-RGRGRCvQGVCLcHVGYGGEDCGqeeppasACPGGCGPRELCRAGQC 703
Cdd:NF041328   96 CEGGACREACsEGLTRC-GGACV-DLATDPLHCG-------ACGVACDPGESCRGGAC 144

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

753-829

7.50e-04

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 41.06 E-value: 7.50e-04

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188528648    753 EGMRMHLLEETTVRTEWTPAPGP-VDAYEIQFIPTTEGASPPF-TARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWG 829
Cdd:smart00060    5 SNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSEWkEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83

FN3

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...

3258-3326

7.57e-04

Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 41.06 E-value: 7.57e-04

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 188528648   3258 PVEPRlgELAVAAVTSDSVGLSWT-----VAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKF 3326
Cdd:smart00060    1 PSPPS--NLRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEF 72

C_rich_MXAN6577

MXAN_6577-like cysteine-rich domain;

492-581

8.00e-04

MXAN_6577-like cysteine-rich domain;

Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 42.82 E-value: 8.00e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648  492 CGtrACPGDCRGRGRCVDGRCVCNPGFT--GEDCGSRR--------CPGDCRGHGLCEDGVC--VCDAGYsgEDCStRSC 559
Cdd:NF041328   42 CG--ACGVACGAGQTCVAGACGCGPGTVacGGACVDTAsdpahcgaCGAACAPGQVCEGGACreACSEGL--TRCG-GAC 116

                          90       100
                  ....*....|....*....|....
gi 188528648  560 PGGCRGRGQCldGRC--VCEDGYS 581
Cdd:NF041328  117 VDLATDPLHC--GACgvACDPGES 138

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

719-745

8.21e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.59 E-value: 8.21e-04

                           10        20
                   ....*....|....*....|....*..
gi 188528648   719 CPGDCRGRGECHDGSCVCKDGYAGEDC 745
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

563-585

8.46e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 39.25 E-value: 8.46e-04

                           10        20
                   ....*....|....*....|....*
gi 188528648   563 CRGRGQCLD--GRCVCEDGYSGEDC 585
Cdd:pfam07974    2 CSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

218-245

8.79e-04

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.20 E-value: 8.79e-04

                           10        20
                   ....*....|....*....|....*...
gi 188528648   218 CPGDCQGRGRCVQGVCVCRAGFSGPDCS 245
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

315-337

9.15e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 39.25 E-value: 9.15e-04

                           10        20
                   ....*....|....*....|....*
gi 188528648   315 CSQRGRCKD--GRCVCDPGYTGEDC 337
Cdd:pfam07974    2 CSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

531-554

1.44e-03

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 38.48 E-value: 1.44e-03

                           10        20
                   ....*....|....*....|....*.
gi 188528648   531 DCRGHGLCED--GVCVCDAGYSGEDC 554
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

590-617

1.71e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.43 E-value: 1.71e-03

                           10        20
                   ....*....|....*....|....*...
gi 188528648   590 CPNDCSQHGVCQDGVCICWEGYVSEDCS 617
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29

GGGWT_bact

NF040941

fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ...

4053-4067

1.79e-03

Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 38.70 E-value: 1.79e-03

                          10
                  ....*....|....*
gi 188528648 4053 PLNVFCDMETDGGGW 4067
Cdd:NF040941   29 PFQVYCDMTTDGGGW 43

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

404-430

2.19e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.43 E-value: 2.19e-03

                           10        20
                   ....*....|....*....|....*..
gi 188528648   404 CPGDCNQRGRCEDGRCVCWPGYTGTDC 430
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

EGF_Tenascin

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

652-678

2.49e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.

Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.05 E-value: 2.49e-03

                           10        20
                   ....*....|....*....|....*..
gi 188528648   652 CPADCRGRGRCVQGVCLCHVGYGGEDC 678
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28

FN3

Fibronectin type 3 domain [General function prediction only];

3560-3679

2.79e-03

Fibronectin type 3 domain [General function prediction only];

Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 43.84 E-value: 2.79e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188528648 3560 LTVTDTTPDSMRLSWS-VAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS--A 3636
Cdd:COG3401   239 LTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSnvV 318

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 188528648 3637 EGTTGLAPAGQTSEesrprlsqLSVTDVTTSSLRLNWEAPPGA 3679
Cdd:COG3401   319 SVTTDLTPPAAPSG--------LTATAVGSSSITLSWTASSDA 353

EGF_2

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

345-368

2.89e-03

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.

Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.71 E-value: 2.89e-03

                           10        20
                   ....*....|....*....|....*.
gi 188528648   345 DCGEGGRCVD--GRCVCWPGYTGEDC 368
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26

EGF_Tenascin