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Conserved domains on  [gi|100814339|ref|NP_065930|]
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coiled-coil domain-containing protein 146 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
122-897 6.81e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member pfam02463:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 6.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   122 KMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKitKPGEMEKKMKILRESTEELRKEIMQKKLEiknlRE 201
Cdd:pfam02463  213 YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES--SKQEIEKEEEKLAQVLKENKEEEKEKKLQ----EE 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   202 DLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL-----------EQEVKTLN 270
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELeikreaeeeeeEELEKLQE 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   271 DSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENE--ATSLTERGILDLNLRNSLIDKQNYHD 348
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEdlLKEEKKEELEILEEEEESIELKQGKL 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   349 ELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERrrelhKEVEVAKRNLAQQKIISE 428
Cdd:pfam02463  447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES-----KARSGLKVLLALIKDGVG 521
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   429 MESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIY 508
Cdd:pfam02463  522 GRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDP 601
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   509 RRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKER----------HKMSLNELEILRNSAVSQERKLQNSMLKHANNV 578
Cdd:pfam02463  602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKesakakesglRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL 681
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   579 TIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLrKRYEKAVQHRNESGVQLIEREEEICIFYEKI 658
Cdd:pfam02463  682 QEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQE-AQDKINEELKLLKQKIDEEEEEEEKSRLKKE 760
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   659 NIQEKMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFV---KPD 735
Cdd:pfam02463  761 EKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEEleeLAL 840
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   736 GENRARFLPGKDLTEKEMIQKLDKLELQLAKKEEKLLEKDFIyEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKN 815
Cdd:pfam02463  841 ELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQ-KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   816 A-TEKMMALVAELSMKQALTIELQKEVREKEDFIFTCNSRIEKGLPLNKEIEKEWLKVLRDEEMHALAIAEKSQEFLEAD 894
Cdd:pfam02463  920 EeRIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999

                   ...
gi 100814339   895 NRQ 897
Cdd:pfam02463 1000 LEE 1002
 
Name Accession Description Interval E-value
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
122-897 6.81e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 6.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   122 KMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKitKPGEMEKKMKILRESTEELRKEIMQKKLEiknlRE 201
Cdd:pfam02463  213 YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES--SKQEIEKEEEKLAQVLKENKEEEKEKKLQ----EE 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   202 DLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL-----------EQEVKTLN 270
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELeikreaeeeeeEELEKLQE 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   271 DSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENE--ATSLTERGILDLNLRNSLIDKQNYHD 348
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEdlLKEEKKEELEILEEEEESIELKQGKL 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   349 ELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERrrelhKEVEVAKRNLAQQKIISE 428
Cdd:pfam02463  447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES-----KARSGLKVLLALIKDGVG 521
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   429 MESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIY 508
Cdd:pfam02463  522 GRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDP 601
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   509 RRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKER----------HKMSLNELEILRNSAVSQERKLQNSMLKHANNV 578
Cdd:pfam02463  602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKesakakesglRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL 681
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   579 TIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLrKRYEKAVQHRNESGVQLIEREEEICIFYEKI 658
Cdd:pfam02463  682 QEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQE-AQDKINEELKLLKQKIDEEEEEEEKSRLKKE 760
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   659 NIQEKMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFV---KPD 735
Cdd:pfam02463  761 EKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEEleeLAL 840
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   736 GENRARFLPGKDLTEKEMIQKLDKLELQLAKKEEKLLEKDFIyEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKN 815
Cdd:pfam02463  841 ELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQ-KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   816 A-TEKMMALVAELSMKQALTIELQKEVREKEDFIFTCNSRIEKGLPLNKEIEKEWLKVLRDEEMHALAIAEKSQEFLEAD 894
Cdd:pfam02463  920 EeRIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999

                   ...
gi 100814339   895 NRQ 897
Cdd:pfam02463 1000 LEE 1002
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
124-440 4.06e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 4.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 124 REQLLKYQnEYNAvKEREFHNQYRLNSLKEEKIIIVKEFEKITkpgEMEKKMKILRESTEELRKEIMQKKLEIKNLREDL 203
Cdd:COG1196  209 AEKAERYR-ELKE-ELKELEAELLLLKLRELEAELEELEAELE---ELEAELEELEAELAELEAELEELRLELEELELEL 283
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 204 ASKQKQLLKEQKELEELLGhqvvlkdEVAHHQtipvqigKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAI 283
Cdd:COG1196  284 EEAQAEEYELLAELARLEQ-------DIARLE-------ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 284 VDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRN 363
Cdd:COG1196  350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 100814339 364 LRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAE 440
Cdd:COG1196  430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
183-844 4.07e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 4.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   183 EELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL 262
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   263 EQEVKTLNDSLKKVENK-------VSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARE-----NEATSLTERG 330
Cdd:TIGR02168  315 ERQLEELEAQLEELESKldelaeeLAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEqletlRSKVAQLELQ 394
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   331 ILDLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRELH 410
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   411 KEVEVAKRNLAQQKIISEMESKLVE--QQLAEENKLLKEQENMKELVVNLLrMTQIKIDEKEQKSK-------------- 474
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQEnlEGFSEGVKALLKNQSGLSGILGVL-SELISVDEGYEAAIeaalggrlqavvve 553
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   475 ---------DFLK-AQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKE 544
Cdd:TIGR02168  554 nlnaakkaiAFLKqNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDN 633
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   545 ----RHKMSLNEL------EILRNSAVS--QERKLQNSMLKH----ANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNN 608
Cdd:TIGR02168  634 alelAKKLRPGYRivtldgDLVRPGGVItgGSAKTNSSILERrreiEELEEKIEELEEKIAELEKALAELRKELEELEEE 713
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   609 IDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIAE 688
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   689 KQRQIcvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLTEK--EMIQKLDKLELQLAK 766
Cdd:TIGR02168  794 LKEEL---KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDieSLAAEIEELEELIEE 870
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 100814339   767 KEEKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREK 844
Cdd:TIGR02168  871 LESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
PTZ00121 PTZ00121
MAEBL; Provisional
82-667 3.37e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 3.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   82 QESEVQLLQNAKRFTEQIQQQQFHLQQADNFPEAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKeekiiivKE 161
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAK-------KK 1310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  162 FEKITKPGEMEKKMKILRESTEELRK--EIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPV 239
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKkaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  240 QIGKEIEKITR---------KKVEMEKKKI----VLEQEVKTLNDSLKKVENKVSAIVDEK--------ENVIKEVEGKR 298
Cdd:PTZ00121 1391 KKADEAKKKAEedkkkadelKKAAAAKKKAdeakKKAEEKKKADEAKKKAEEAKKADEAKKkaeeakkaEEAKKKAEEAK 1470
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  299 ALLEIKE-----REHNQLVKLLELARE--NEATSLTERGILDLNLRNSliDKQNYHDELsrKQREKERDFRNLRKMELLL 371
Cdd:PTZ00121 1471 KADEAKKkaeeaKKADEAKKKAEEAKKkaDEAKKAAEAKKKADEAKKA--EEAKKADEA--KKAEEAKKADEAKKAEEKK 1546
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  372 KVswDALRQTQAL---HQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQ 448
Cdd:PTZ00121 1547 KA--DELKKAEELkkaEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  449 ENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEirihKKKKCEIYRRLREfaklydtirNERNKF 528
Cdd:PTZ00121 1625 LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE----DKKKAEEAKKAEE---------DEKKAA 1691
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  529 VNLLHKAHQ--KVNEIKERHKMSLNELEILRNSavSQERKLQNSMLKhannvtiRESMQNDVRKIVSKLQEMKEKKEAQL 606
Cdd:PTZ00121 1692 EALKKEAEEakKAEELKKKEAEEKKKAEELKKA--EEENKIKAEEAK-------KEAEEDKKKAEEAKKDEEEKKKIAHL 1762
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 100814339  607 NNIDRLANTITMIEEEMVqlrkrYEKAVQHRNESGVQLIEREEEIcIFYEKINIQEKMKLN 667
Cdd:PTZ00121 1763 KKEEEKKAEEIRKEKEAV-----IEEELDEEDEKRRMEVDKKIKD-IFDNFANIIEGGKEG 1817
 
Name Accession Description Interval E-value
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
122-897 6.81e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 6.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   122 KMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKitKPGEMEKKMKILRESTEELRKEIMQKKLEiknlRE 201
Cdd:pfam02463  213 YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES--SKQEIEKEEEKLAQVLKENKEEEKEKKLQ----EE 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   202 DLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL-----------EQEVKTLN 270
Cdd:pfam02463  287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELeikreaeeeeeEELEKLQE 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   271 DSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENE--ATSLTERGILDLNLRNSLIDKQNYHD 348
Cdd:pfam02463  367 KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEdlLKEEKKEELEILEEEEESIELKQGKL 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   349 ELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERrrelhKEVEVAKRNLAQQKIISE 428
Cdd:pfam02463  447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES-----KARSGLKVLLALIKDGVG 521
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   429 MESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIY 508
Cdd:pfam02463  522 GRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDP 601
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   509 RRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKER----------HKMSLNELEILRNSAVSQERKLQNSMLKHANNV 578
Cdd:pfam02463  602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKesakakesglRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL 681
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   579 TIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLrKRYEKAVQHRNESGVQLIEREEEICIFYEKI 658
Cdd:pfam02463  682 QEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQE-AQDKINEELKLLKQKIDEEEEEEEKSRLKKE 760
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   659 NIQEKMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFV---KPD 735
Cdd:pfam02463  761 EKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEEleeLAL 840
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   736 GENRARFLPGKDLTEKEMIQKLDKLELQLAKKEEKLLEKDFIyEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKN 815
Cdd:pfam02463  841 ELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQ-KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   816 A-TEKMMALVAELSMKQALTIELQKEVREKEDFIFTCNSRIEKGLPLNKEIEKEWLKVLRDEEMHALAIAEKSQEFLEAD 894
Cdd:pfam02463  920 EeRIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999

                   ...
gi 100814339   895 NRQ 897
Cdd:pfam02463 1000 LEE 1002
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
124-440 4.06e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 4.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 124 REQLLKYQnEYNAvKEREFHNQYRLNSLKEEKIIIVKEFEKITkpgEMEKKMKILRESTEELRKEIMQKKLEIKNLREDL 203
Cdd:COG1196  209 AEKAERYR-ELKE-ELKELEAELLLLKLRELEAELEELEAELE---ELEAELEELEAELAELEAELEELRLELEELELEL 283
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 204 ASKQKQLLKEQKELEELLGhqvvlkdEVAHHQtipvqigKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAI 283
Cdd:COG1196  284 EEAQAEEYELLAELARLEQ-------DIARLE-------ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 284 VDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRN 363
Cdd:COG1196  350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 100814339 364 LRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAE 440
Cdd:COG1196  430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
183-844 4.07e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 4.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   183 EELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVL 262
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   263 EQEVKTLNDSLKKVENK-------VSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARE-----NEATSLTERG 330
Cdd:TIGR02168  315 ERQLEELEAQLEELESKldelaeeLAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEqletlRSKVAQLELQ 394
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   331 ILDLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRELH 410
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   411 KEVEVAKRNLAQQKIISEMESKLVE--QQLAEENKLLKEQENMKELVVNLLrMTQIKIDEKEQKSK-------------- 474
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQEnlEGFSEGVKALLKNQSGLSGILGVL-SELISVDEGYEAAIeaalggrlqavvve 553
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   475 ---------DFLK-AQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKE 544
Cdd:TIGR02168  554 nlnaakkaiAFLKqNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDN 633
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   545 ----RHKMSLNEL------EILRNSAVS--QERKLQNSMLKH----ANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNN 608
Cdd:TIGR02168  634 alelAKKLRPGYRivtldgDLVRPGGVItgGSAKTNSSILERrreiEELEEKIEELEEKIAELEKALAELRKELEELEEE 713
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   609 IDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIAE 688
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   689 KQRQIcvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLTEK--EMIQKLDKLELQLAK 766
Cdd:TIGR02168  794 LKEEL---KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDieSLAAEIEELEELIEE 870
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 100814339   767 KEEKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREK 844
Cdd:TIGR02168  871 LESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
124-774 1.86e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 1.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   124 REQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFekitkpGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDL 203
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEV------SELEEEIEELQKELYALANEISRLEQQKQILRERL 311
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   204 ASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAI 283
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   284 VDEKENVIKEVEGKRALLEIKEREHNQLV--------KLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQR 355
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERLQqeieellkKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   356 EKERDFRNLRKMELLLKVSWDALRQTQALHQ-------RLLLEMEAIPKDDSTLSER---RRELHKEVEVAKRNLAQQKI 425
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkALLKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQAVV 551
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   426 ISEMESKLVEQQLAEENKLLK------EQENMKELVVNLLRMTQ------------IKIDEKEQKSKDFL---------- 477
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRvtflplDSIKGTEIQGNDREILKniegflgvakdlVKFDPKLRKALSYLlggvlvvddl 631
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   478 --------KAQQKYTNIVKE--------------------MKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFV 529
Cdd:TIGR02168  632 dnalelakKLRPGYRIVTLDgdlvrpggvitggsaktnssILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   530 NLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNI 609
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI 791
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   610 DRLANTITMIEEEMVQLRKRY--EKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIhlLEEKIQFLKMKIA 687
Cdd:TIGR02168  792 EQLKEELKALREALDELRAELtlLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES--LAAEIEELEELIE 869
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   688 EKQRQIcvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRArflpgKDLTEKEMIQKLDKLELQLAKK 767
Cdd:TIGR02168  870 ELESEL---EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE-----LREKLAQLELRLEGLEVRIDNL 941

                   ....*..
gi 100814339   768 EEKLLEK 774
Cdd:TIGR02168  942 QERLSEE 948
PTZ00121 PTZ00121
MAEBL; Provisional
82-667 3.37e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 3.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   82 QESEVQLLQNAKRFTEQIQQQQFHLQQADNFPEAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKeekiiivKE 161
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAK-------KK 1310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  162 FEKITKPGEMEKKMKILRESTEELRK--EIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPV 239
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKkaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  240 QIGKEIEKITR---------KKVEMEKKKI----VLEQEVKTLNDSLKKVENKVSAIVDEK--------ENVIKEVEGKR 298
Cdd:PTZ00121 1391 KKADEAKKKAEedkkkadelKKAAAAKKKAdeakKKAEEKKKADEAKKKAEEAKKADEAKKkaeeakkaEEAKKKAEEAK 1470
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  299 ALLEIKE-----REHNQLVKLLELARE--NEATSLTERGILDLNLRNSliDKQNYHDELsrKQREKERDFRNLRKMELLL 371
Cdd:PTZ00121 1471 KADEAKKkaeeaKKADEAKKKAEEAKKkaDEAKKAAEAKKKADEAKKA--EEAKKADEA--KKAEEAKKADEAKKAEEKK 1546
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  372 KVswDALRQTQAL---HQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQ 448
Cdd:PTZ00121 1547 KA--DELKKAEELkkaEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  449 ENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEirihKKKKCEIYRRLREfaklydtirNERNKF 528
Cdd:PTZ00121 1625 LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE----DKKKAEEAKKAEE---------DEKKAA 1691
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  529 VNLLHKAHQ--KVNEIKERHKMSLNELEILRNSavSQERKLQNSMLKhannvtiRESMQNDVRKIVSKLQEMKEKKEAQL 606
Cdd:PTZ00121 1692 EALKKEAEEakKAEELKKKEAEEKKKAEELKKA--EEENKIKAEEAK-------KEAEEDKKKAEEAKKDEEEKKKIAHL 1762
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 100814339  607 NNIDRLANTITMIEEEMVqlrkrYEKAVQHRNESGVQLIEREEEIcIFYEKINIQEKMKLN 667
Cdd:PTZ00121 1763 KKEEEKKAEEIRKEKEAV-----IEEELDEEDEKRRMEVDKKIKD-IFDNFANIIEGGKEG 1817
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
169-492 4.33e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 4.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   169 GEMEKKMKILRESTEelrkeimqKKLEIKNLREDLASKQKQLLK-----EQKELEELLGHQVVLKDEVAHHQTIPVQIGK 243
Cdd:TIGR02168  196 NELERQLKSLERQAE--------KAERYKELKAELRELELALLVlrleeLREELEELQEELKEAEEELEELTAELQELEE 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   244 EIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEA 323
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   324 TSLTERgildLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMElllkvswDALRQTQALHQRLLLEMEAIPKDdstLS 403
Cdd:TIGR02168  348 ELKEEL----ESLEAELEELEAELEELESRLEELEEQLETLRSKV-------AQLELQIASLNNEIERLEARLER---LE 413
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   404 ERRRELHKEVEvakrnlAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKY 483
Cdd:TIGR02168  414 DRRERLQQEIE------ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                   ....*....
gi 100814339   484 TNIVKEMKA 492
Cdd:TIGR02168  488 QARLDSLER 496
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
118-409 8.76e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 8.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 118 TEVSKMREQLLKYQNEYNAVKEREF--------------HNQYRLNSLKEEKIIIVKEFEKItkpgemEKKMKILRESTE 183
Cdd:COG1196  267 AELEELRLELEELELELEEAQAEEYellaelarleqdiaRLEERRRELEERLEELEEELAEL------EEELEELEEELE 340
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 184 ELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLE 263
Cdd:COG1196  341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE 420
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 264 QEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDK 343
Cdd:COG1196  421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 100814339 344 QNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRREL 409
Cdd:COG1196  501 ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
404-797 1.53e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 1.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   404 ERRRELHKEVEVAKRNLAQ-QKIISEMESKLV----EQQLAEENKLLKEQENMKELVVNLLRMTQiKIDEKEQKSKDFLK 478
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRlEDILNELERQLKslerQAEKAERYKELKAELRELELALLVLRLEE-LREELEELQEELKE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   479 AQQKYTNIVKEMKAKDLEIRIHKKKKceiyrrlrefaklydtirnernkfvnllHKAHQKVNEIKERhkmsLNELEILRN 558
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEV----------------------------SELEEEIEELQKE----LYALANEIS 298
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   559 SAVSQERKLQNSMlkhANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKRYEKAVQHRN 638
Cdd:TIGR02168  299 RLEQQKQILRERL---ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE 375
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   639 EsgvqliereeeicifyekiniqekmklngeieihlLEEKIQFLKMKIAEKQRQICVTQKLLpakRSLDADLAVLQIQFS 718
Cdd:TIGR02168  376 E-----------------------------------LEEQLETLRSKVAQLELQIASLNNEI---ERLEARLERLEDRRE 417
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 100814339   719 QCTDRIKDLEKQFVKPDGENRARFLPGKDLTEKEMIQKLDKLELQLAKKEEKLLEKDFIYEQVSRLTDRLCSKTQGCKQ 797
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
243-544 1.99e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 1.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   243 KEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENE 322
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   323 ATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTL 402
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   403 SERRRELHKEVEVAKRNLAqqKIISEMES--KLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQ 480
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIE--SLAAEIEEleELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 100814339   481 QKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKL-YDTIRNERNKFVNLLHKAHQKVNEIKE 544
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLtLEEAEALENKIEDDEEEARRRLKRLEN 979
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
114-603 2.65e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 2.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 114 EAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQKK 193
Cdd:PRK03918 234 EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 194 LEIKNLREDLASKQKQLLK---EQKELEELLGHQVVLKDEVAHHQTipvqIGKEIEKITRKKVEMEK-KKIVLEQEVKTL 269
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEE----RHELYEEAKAKKEELERlKKRLTGLTPEKL 389
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 270 NDSLKKVENKVSAIVDEkenvIKEVEGKRALLEIKEREHNQLVKLLELAR-----------ENEATSLTERGILDLnlrN 338
Cdd:PRK03918 390 EKELEELEKAKEEIEEE----ISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgreltEEHRKELLEEYTAEL---K 462
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 339 SLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRL----LLEMEAIPKDDSTLSERRRELHKEVE 414
Cdd:PRK03918 463 RIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLkkynLEELEKKAEEYEKLKEKLIKLKGEIK 542
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 415 VAKRNLaqqKIISEMESKLVEQqlaeENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIvkemkakd 494
Cdd:PRK03918 543 SLKKEL---EKLEELKKKLAEL----EKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL-------- 607
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 495 leirihKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKE-RHKMSLNELEILRNSAVSQERKLQNSMLK 573
Cdd:PRK03918 608 ------KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEElEKKYSEEEYEELREEYLELSRELAGLRAE 681
                        490       500       510
                 ....*....|....*....|....*....|
gi 100814339 574 HANNVTIRESMQNDVRKIVSKLQEMKEKKE 603
Cdd:PRK03918 682 LEELEKRREEIKKTLEKLKEELEEREKAKK 711
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
115-733 1.12e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.26  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   115 AFSTEVSKMREQLlkyQNEYNAVKEREFHNQYRLNSLKEEKiiivkefekitkpgemEKKMKIL-RESTEELRKEIMQKK 193
Cdd:pfam15921  217 SLGSAISKILREL---DTEISYLKGRIFPVEDQLEALKSES----------------QNKIELLlQQHQDRIEQLISEHE 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   194 LEIKNLREDLASKQKQLLKEQKELEellghqvVLKDEVAHHQTIPVQIGKEIEK-ITRKKVEMEKKKIVLEQEVKTLNDS 272
Cdd:pfam15921  278 VEITGLTEKASSARSQANSIQSQLE-------IIQEQARNQNSMYMRQLSDLEStVSQLRSELREAKRMYEDKIEELEKQ 350
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   273 LKKVENKVSAIVDEKENVIKEV-----EGKRALLEIKEREHnqlvkllELARENEATSL-----TERGILDLNLRNSLID 342
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESgnlddQLQKLLADLHKREK-------ELSLEKEQNKRlwdrdTGNSITIDHLRRELDD 423
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   343 KQNYHDEL--------SRKQREKERDFRNLR-KMELLLKVS--WDALRQTQALHQRLLLEMEA----IPKDDSTLSERRR 407
Cdd:pfam15921  424 RNMEVQRLeallkamkSECQGQMERQMAAIQgKNESLEKVSslTAQLESTKEMLRKVVEELTAkkmtLESSERTVSDLTA 503
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   408 ELH-KEVEVAKRNLAQQKIISEMESKLVE-----------QQLAEENKLLKEQENMKELVVNLLR-----MTQIKidekE 470
Cdd:pfam15921  504 SLQeKERAIEATNAEITKLRSRVDLKLQElqhlknegdhlRNVQTECEALKLQMAEKDKVIEILRqqienMTQLV----G 579
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   471 QKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSL 550
Cdd:pfam15921  580 QHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLL 659
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   551 NELEILRN--SAVSQERKLQNSMLKHANnvtirESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRK 628
Cdd:pfam15921  660 NEVKTSRNelNSLSEDYEVLKRNFRNKS-----EEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK 734
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   629 ryekavqhrnesgvQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIA----EKQRQICVTQKLLPAKR 704
Cdd:pfam15921  735 --------------QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELStvatEKNKMAGELEVLRSQER 800
                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 100814339   705 SLDADLAVLQI-------QFSQCTDRIKDLEKQFVK 733
Cdd:pfam15921  801 RLKEKVANMEValdkaslQFAECQDIIQRQEQESVR 836
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
62-730 1.41e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339    62 TRMAALKAKYTLLHDAVMSTQESEVQLLQNAKRFTEQIQQQQFHLQQADNFPEAFSTEVSKMREQLLKYQNEYNAVKERE 141
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEEL 339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   142 FHNQYRLNSLKEEKIIIVKEF-EKITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLR----------EDLASKQKQL 210
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELeELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNneierlearlERLEDRRERL 419
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   211 LKEQKELEELLGHQVV--LKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKE 288
Cdd:TIGR02168  420 QQEIEELLKKLEEAELkeLQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   289 NVIKEVEGKRALLEIKER---EHNQLVKLLELARENE-ATSLTERGILDLNLRNSL--------IDKQN----------- 345
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGlsgILGVLSELISVDEGYEaAIEAALGGRLQAVVVENLnaakkaiaFLKQNelgrvtflpld 579
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   346 -----YHDELSRKQREKERDFR----NLRKMELLLKVSWDAL--------RQTQALHQR--LLLEMEAIPKDDSTLSERR 406
Cdd:TIGR02168  580 sikgtEIQGNDREILKNIEGFLgvakDLVKFDPKLRKALSYLlggvlvvdDLDNALELAkkLRPGYRIVTLDGDLVRPGG 659
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   407 RELHKEVEVAKRNLAQQKIISEMESKlVEQQLAEENKLLKEQENMKELVVNLLrmtqikiDEKEQKSKDFLKAQQKYTNI 486
Cdd:TIGR02168  660 VITGGSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELE-------EELEQLRKELEELSRQISAL 731
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   487 VKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERK 566
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   567 LQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIE 646
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   647 REEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAV-----LQIQFSQCT 721
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEalenkIEDDEEEAR 971

                   ....*....
gi 100814339   722 DRIKDLEKQ 730
Cdd:TIGR02168  972 RRLKRLENK 980
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
126-323 1.49e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 1.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 126 QLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKItkpgemEKKMKILRESTEELRKEIMQKKLEIKNLREDLA- 204
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNEL------QAELEALQAEIDKLQAEIAEAEAEIEERREELGe 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 205 ---SKQKQ--------LLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSL 273
Cdd:COG3883   91 rarALYRSggsvsyldVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 100814339 274 KKVENKVSaivdEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEA 323
Cdd:COG3883  171 AELEAQQA----EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
119-773 2.62e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 2.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   119 EVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEfekitKPGEMEKKMKILRESTEELRKEIMQKKLEIKN 198
Cdd:TIGR02169  252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE-----KIGELEAEIASLERSIAEKERELEDAEERLAK 326
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   199 LREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVEN 278
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   279 KVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELAREN--EATSLTERGILDL-NLRNSLIDKQNYHDELSRKQR 355
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEikKQEWKLEQLAADLsKYEQELYDLKEEYDRVEKELS 486
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   356 EKERDfrnLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIIsemESKLVE 435
Cdd:TIGR02169  487 KLQRE---LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVV---EDDAVA 560
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   436 QQLAEenkLLKEqenmkelvVNLLRMTQIKIDEKEQKSK---------------DFLKAQQKYTNIVKEM---------- 490
Cdd:TIGR02169  561 KEAIE---LLKR--------RKAGRATFLPLNKMRDERRdlsilsedgvigfavDLVEFDPKYEPAFKYVfgdtlvvedi 629
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   491 -KAKDLEIRIH--------------------------------KKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQ 537
Cdd:TIGR02169  630 eAARRLMGKYRmvtlegelfeksgamtggsraprggilfsrsePAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   538 KVNEIKERHKMSLNELEILRNSAVSQERKLQNSMlkhannvtiresmqndvrkivSKLQEMKEKKEAQLNNIDRLANTIT 617
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE---------------------EDLSSLEQEIENVKSELKELEARIE 768
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   618 MIEEEMVQLRKRYEKAVQHRNESGVQLIERE----EEICIFYEKINIQEKMKLNG-EIEIHLLEEKIQFLKMKIAEKQRQ 692
Cdd:TIGR02169  769 ELEEDLHKLEEALNDLEARLSHSRIPEIQAElsklEEEVSRIEARLREIEQKLNRlTLEKEYLEKEIQELQEQRIDLKEQ 848
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   693 I---CVTQKLLPA-KRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRarflpgkdltekEMIQKLDKLELQLAKKE 768
Cdd:TIGR02169  849 IksiEKEIENLNGkKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR------------ELERKIEELEAQIEKKR 916

                   ....*
gi 100814339   769 EKLLE 773
Cdd:TIGR02169  917 KRLSE 921
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
286-606 2.64e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 44.73  E-value: 2.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  286 EKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLtERgildlnlrnslidkqnyHDELSR-KQREKERDFRNL 364
Cdd:pfam17380 304 EKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAM-ER-----------------ERELERiRQEERKRELERI 365
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  365 RKMELLLKVSwdALRQTQAL-------HQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQ 437
Cdd:pfam17380 366 RQEEIAMEIS--RMRELERLqmerqqkNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEE 443
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  438 LAEENKLLKEQENMKELVVNLLRMTQikidEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIyrrlrefakl 517
Cdd:pfam17380 444 RAREMERVRLEEQERQQQVERLRQQE----EERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMI---------- 509
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  518 ydtirNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDvRKIVSKLQE 597
Cdd:pfam17380 510 -----EEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERE-REMMRQIVE 583

                  ....*....
gi 100814339  598 mKEKKEAQL 606
Cdd:pfam17380 584 -SEKARAEY 591
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
244-497 2.95e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 2.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 244 EIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEA 323
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 324 TSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLS 403
Cdd:COG1196  313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 404 ERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKY 483
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
                        250
                 ....*....|....
gi 100814339 484 TNIVKEMKAKDLEI 497
Cdd:COG1196  473 ALLEAALAELLEEL 486
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
178-788 3.00e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 3.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   178 LRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQtipvqigKEIEKITRKKVEMEK 257
Cdd:TIGR02169  334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR-------EKLEKLKREINELKR 406
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   258 KKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELAREneatsltergildlnlr 337
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ----------------- 469
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   338 nSLIDKQNYHDELSRKQREKERDfrnLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRELHKEVEVAK 417
Cdd:TIGR02169  470 -ELYDLKEEYDRVEKELSKLQRE---LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAA 545
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   418 RNLAQQKIIsemESKLVEQQLAEenkLLKEqenmkelvVNLLRMTQIKIDEKEQKSK---------------DFLKAQQK 482
Cdd:TIGR02169  546 GNRLNNVVV---EDDAVAKEAIE---LLKR--------RKAGRATFLPLNKMRDERRdlsilsedgvigfavDLVEFDPK 611
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   483 YTNIVKEM-----------KAKDLEIRIH--------------------------------KKKKCEIYRRLREFAKLYD 519
Cdd:TIGR02169  612 YEPAFKYVfgdtlvvedieAARRLMGKYRmvtlegelfeksgamtggsraprggilfsrsePAELQRLRERLEGLKRELS 691
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   520 TIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHA---NNVTIRESMQNDVRKIVSKLQ 596
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSsleQEIENVKSELKELEARIEELE 771
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   597 EMKEKKEAQLNNIDR---------LANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQEKMKLN 667
Cdd:TIGR02169  772 EDLHKLEEALNDLEArlshsripeIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   668 GEIEIHLLEEKIQFLKMKIAEKQRQIcvtQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPdgENRARFLPGKD 747
Cdd:TIGR02169  852 IEKEIENLNGKKEELEEELEELEAAL---RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK--RKRLSELKAKL 926
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 100814339   748 LTEKEMIQKLDKLELQLAKKEEKLLEKDFIYEQVSRLTDRL 788
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEI 967
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
298-568 6.44e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 6.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  298 RALLEIKEREHNQLVKLLELARENEATSLTERGILD---------LNLRNSLIDKQNYHDELSRKQREKERdfrnlrkme 368
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQerrealqrlAEYSWDEIDVASAEREIAELEAELER--------- 679
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  369 llLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQK----IISEMESKLVEQQLAEENKL 444
Cdd:COG4913   680 --LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQdrleAAEDLARLELRALLEERFAA 757
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  445 LKEQENMKELVVNLLRMTQIKIDEKEQKSKDFLKAQQKYtNIVKEMKAKDLEIRIhkkkkceiyRRLREFAKLYDTIRNE 524
Cdd:COG4913   758 ALGDAVERELRENLEERIDALRARLNRAEEELERAMRAF-NREWPAETADLDADL---------ESLPEYLALLDRLEED 827
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 100814339  525 R-----------------NKFVNLLHKAHQKVNEIKERhkmsLNEL-EILRNSAVSQERKLQ 568
Cdd:COG4913   828 GlpeyeerfkellnensiEFVADLLSKLRRAIREIKER----IDPLnDSLKRIPFGPGRYLR 885
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
256-830 6.46e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.57  E-value: 6.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   256 EKKKIVLEQEVKTLNDSLKKVENKVSAIVD--------------EKENVIKEVEGKRALLE-IKEREHNQLVKLLELARE 320
Cdd:pfam15921  102 EKQKFYLRQSVIDLQTKLQEMQMERDAMADirrresqsqedlrnQLQNTVHELEAAKCLKEdMLEDSNTQIEQLRKMMLS 181
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   321 NEATSLTERGILdLNLRNSLIDKQNYHDELS------------RKQREKERDFRNLR-------------------KMEL 369
Cdd:pfam15921  182 HEGVLQEIRSIL-VDFEEASGKKIYEHDSMStmhfrslgsaisKILRELDTEISYLKgrifpvedqlealksesqnKIEL 260
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   370 LLKVSWDALRQTQALHQrllLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQK------------IISEMESKLVEQQ 437
Cdd:pfam15921  261 LLQQHQDRIEQLISEHE---VEITGLTEKASSARSQANSIQSQLEIIQEQARNQNsmymrqlsdlesTVSQLRSELREAK 337
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   438 LAEENKLlkeQENMKELVVNLLRMTQIKIdEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKL 517
Cdd:pfam15921  338 RMYEDKI---EELEKQLVLANSELTEART-ERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSIT 413
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   518 YDTIRNErnkfvnlLHKAHQKVNEIKERHKMSLNELE--ILRNSAVSQERklqNSMLKHANNVTIR-ESMQNDVRKIVSK 594
Cdd:pfam15921  414 IDHLRRE-------LDDRNMEVQRLEALLKAMKSECQgqMERQMAAIQGK---NESLEKVSSLTAQlESTKEMLRKVVEE 483
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   595 LQemkeKKEAQLNNIDRLANTITMIEEEMvqlrkryEKAVQHRNESGVQLIEREEeicifyekINIQEKMKLNGEIEiHL 674
Cdd:pfam15921  484 LT----AKKMTLESSERTVSDLTASLQEK-------ERAIEATNAEITKLRSRVD--------LKLQELQHLKNEGD-HL 543
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   675 --LEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDAD----LAVLQIQFSQCTDRIKD--LEKQFVKPDGENrarflpgK 746
Cdd:pfam15921  544 rnVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQhgrtAGAMQVEKAQLEKEINDrrLELQEFKILKDK-------K 616
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   747 DLTEKEMIQKLDKLELQLAKKEEKLLEKDFIYEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAE 826
Cdd:pfam15921  617 DAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNK 696

                   ....
gi 100814339   827 LSMK 830
Cdd:pfam15921  697 LKMQ 700
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
114-310 7.53e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 7.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  114 EAFSTEVSKMREqLLKYQneynavKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQ-- 191
Cdd:pfam17380 368 EEIAMEISRMRE-LERLQ------MERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRrl 440
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  192 ---KKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQ----IGKEIEKITRKKVEMEKKKIVLEQ 264
Cdd:pfam17380 441 eeeRAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQrrkiLEKELEERKQAMIEEERKRKLLEK 520
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 100814339  265 EvktlndslkkVENKVSAIVDEKENVIKEvEGKRALLEIKEREHNQ 310
Cdd:pfam17380 521 E----------MEERQKAIYEEERRREAE-EERRKQQEMEERRRIQ 555
PTZ00121 PTZ00121
MAEBL; Provisional
154-874 9.55e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 9.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  154 EKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAH 233
Cdd:PTZ00121 1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDAR 1164
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  234 HQTIP--VQIGKEIEKiTRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNql 311
Cdd:PTZ00121 1165 KAEEArkAEDAKKAEA-ARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE-- 1241
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  312 VKLLELARENEATSLTERGILDLNLRNSLIDK---QNYHDELsrKQREKERDFRNLRKMELLLKVSWDALRQTQALH-QR 387
Cdd:PTZ00121 1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKaeeARKADEL--KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKaDE 1319
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  388 LLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKID 467
Cdd:PTZ00121 1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  468 EKEQKSK-DFLKAQQKYTNIVKEMKAKDLEIRIHK--KKKCEIYRRLREFAKLYDtirnERNKFVNLLHKAHQ--KVNEI 542
Cdd:PTZ00121 1400 AEEDKKKaDELKKAAAAKKKADEAKKKAEEKKKADeaKKKAEEAKKADEAKKKAE----EAKKAEEAKKKAEEakKADEA 1475
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  543 KERHKMSlNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEA-QLNNIDRLANTITMIEE 621
Cdd:PTZ00121 1476 KKKAEEA-KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAdEAKKAEEKKKADELKKA 1554
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  622 EMVQLRKRYEKAVQ-HRNESGVQLIEREEEICIFYEKINIQEKMKLNGEieihllEEKIQFLKMKIAEKQRqicvtQKLL 700
Cdd:PTZ00121 1555 EELKKAEEKKKAEEaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE------EKKMKAEEAKKAEEAK-----IKAE 1623
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  701 PAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLTEKEMIQKLDKLELQLAKKEEKLL---EKDFI 777
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeaEEAKK 1703
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  778 YEQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREKEDFIFTCNSRIEK 857
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
                         730
                  ....*....|....*..
gi 100814339  858 GlpLNKEIEKEWLKVLR 874
Cdd:PTZ00121 1784 E--LDEEDEKRRMEVDK 1798
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
159-510 9.66e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 9.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   159 VKEFEKITKPGEMEKKMKILRESteeLRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIP 238
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSS---LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL 746
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   239 VQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVE-----NKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVK 313
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarlshSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   314 LLELARENEATSLTERGILDLNlRNSLIDKQnyhDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEME 393
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQ-IKSIEKEI---ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   394 AIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIK---IDEKE 470
Cdd:TIGR02169  903 RKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNmlaIQEYE 982
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 100814339   471 QKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRR 510
Cdd:TIGR02169  983 EVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
120-568 1.39e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 1.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 120 VSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKIT----KPGEMEKKMKILRESTEELRKEIMQKKLE 195
Cdd:PRK03918 195 IKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEelekELESLEGSKRKLEEKIRELEERIEELKKE 274
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 196 IKNLREdlasKQKQLLKEQKELEELLghqvvlkdevahhqtipvQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKK 275
Cdd:PRK03918 275 IEELEE----KVKELKELKEKAEEYI------------------KLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKE 332
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 276 VENKVSAIvDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEAtSLTERGILDLNLRNSLIDKQNyhDELSRKQR 355
Cdd:PRK03918 333 LEEKEERL-EELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKK-RLTGLTPEKLEKELEELEKAK--EEIEEEIS 408
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 356 EKERDFRNLRKMELLLKVSWDALRQTQA----------------LHQRLLLEMEAIPKDDSTLSERRRELHKE-VEVAKR 418
Cdd:PRK03918 409 KITARIGELKKEIKELKKAIEELKKAKGkcpvcgrelteehrkeLLEEYTAELKRIEKELKEIEEKERKLRKElRELEKV 488
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 419 NLAQQKIIS---------EMESKLVEQQLAEENKLLKEQENMKELVVNLlrMTQIKIDEKEQKSKDFLKaqqkytnivKE 489
Cdd:PRK03918 489 LKKESELIKlkelaeqlkELEEKLKKYNLEELEKKAEEYEKLKEKLIKL--KGEIKSLKKELEKLEELK---------KK 557
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 100814339 490 MKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQ 568
Cdd:PRK03918 558 LAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELA 636
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
145-898 1.47e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 1.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   145 QYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTeELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQ 224
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELII-DLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDY 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   225 VVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKE----VEGKRAL 300
Cdd:pfam02463  232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSellkLERRKVD 311
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   301 LEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKErdfRNLRKMELLLKVSWDALRQ 380
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE---QLEEELLAKKKLESERLSS 388
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   381 TQALHQRLLLEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLR 460
Cdd:pfam02463  389 AAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK 468
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   461 MTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAKDLEIRIHKKKKCEIYRRLREFAKLYDTIRNERNKFVNLLHKAHQKVN 540
Cdd:pfam02463  469 KSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTA 548
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   541 EIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIE 620
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI 628
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   621 EEMVQLRKRYEKAVqhRNESGVQLIEREEEICIFYEKINIQEKMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLL 700
Cdd:pfam02463  629 LKDTELTKLKESAK--AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   701 PAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRARFLPGKDLTEKEMIQKLDKL--ELQLAKKEEKLLEKDFIY 778
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKseLSLKEKELAEEREKTEKL 786
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   779 EQVSRLTDRLCSKTQGCKQDTLLLAKKMNGYQRRIKNATEKMMALVAELSMKQALTIELQKEVREKEDFIFTCNSRIEKG 858
Cdd:pfam02463  787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKE 866
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 100814339   859 LPLNKEIEKEW-LKVLRDEEMHALAIAEKSQEFLEADNRQL 898
Cdd:pfam02463  867 ELLQELLLKEEeLEEQKLKDELESKEEKEKEEKKELEEESQ 907
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
270-650 1.50e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.52  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   270 NDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDE 349
Cdd:pfam12128  192 EGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   350 LSRKQREKERDFRNLRKMELLLkvswdalrqtqalhqrlllemeaipKDDSTLSERRRELHKEVEVAKRNLAQQKiiSEM 429
Cdd:pfam12128  272 TLIASRQEERQETSAELNQLLR-------------------------TLDDQWKEKRDELNGELSAADAAVAKDR--SEL 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   430 EsklveqqLAEENKLLKEQENMKELVVNLLRMTQIKID--EKEQKSKDFLKAQQKYTNivkemKAKDLEIRIHKKKKCEI 507
Cdd:pfam12128  325 E-------ALEDQHGAFLDADIETAAADQEQLPSWQSEleNLEERLKALTGKHQDVTA-----KYNRRRSKIKEQNNRDI 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   508 YRRLREFAKLYDTIRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSmlkhannVTIRESMQND 587
Cdd:pfam12128  393 AGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQ-------ATATPELLLQ 465
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 100814339   588 VRKIVSKLQEMKEKKEAQLNNIDRLANtitmieeEMVQLRKRYEKAVQHRNESGVQLIEREEE 650
Cdd:pfam12128  466 LENFDERIERAREEQEAANAEVERLQS-------ELRQARKRRDQASEALRQASRRLEERQSA 521
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
124-620 1.52e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.73  E-value: 1.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   124 REQLLKYQNEYNAVKEREFHNqyrLNSLKEEKII---IVKEFEK--ITKPGEMEKKMKILRESTEELRK-EIMQKkleIK 197
Cdd:TIGR01612  930 KESIEKFHNKQNILKEILNKN---IDTIKESNLIeksYKDKFDNtlIDKINELDKAFKDASLNDYEAKNnELIKY---FN 1003
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   198 NLREDLASKQKQLLKEQKELEELLGHQVVLKD----------EVAHHQTIpVQIGKEIEKITRKKVEMEKKKIVLEQEVK 267
Cdd:TIGR01612 1004 DLKANLGKNKENMLYHQFDEKEKATNDIEQKIedanknipniEIAIHTSI-YNIIDEIEKEIGKNIELLNKEILEEAEIN 1082
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   268 TLN-----DSLK-------------KVENKVSAIVDEKENVIKEVEGK-RALLEIKEREHNQLVKLLelARENEATSLTE 328
Cdd:TIGR01612 1083 ITNfneikEKLKhynfddfgkeeniKYADEINKIKDDIKNLDQKIDHHiKALEEIKKKSENYIDEIK--AQINDLEDVAD 1160
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   329 RGILDLNLRNSLIDKQNyhdeLSRKQREKERDFRNLRKmelllkvswdalrqtqalhqrLLLEMEAIPKDDSTLSErrre 408
Cdd:TIGR01612 1161 KAISNDDPEEIEKKIEN----IVTKIDKKKNIYDEIKK---------------------LLNEIAEIEKDKTSLEE---- 1211
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   409 lhkeveVAKRNLAQQKIIsemesklveqqlaeeNKLLKEQenmkelvvnllrmtqikIDEKEQKSKDFLKAQQKYTNIVK 488
Cdd:TIGR01612 1212 ------VKGINLSYGKNL---------------GKLFLEK-----------------IDEEKKKSEHMIKAMEAYIEDLD 1253
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   489 EMKAKDLEIRIHKKKKCEIYRRLREFA------KLYDTIRNERNKFVNLLHKAHQKVNEIKERhKMSLNELEILRNSAVS 562
Cdd:TIGR01612 1254 EIKEKSPEIENEMGIEMDIKAEMETFNishdddKDHHIISKKHDENISDIREKSLKIIEDFSE-ESDINDIKKELQKNLL 1332
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 100814339   563 QERKLQNSMLKHANNVTIRESM--QNDVRKIVSKLQEMKEKKEAQLNNI-DRLANTITMIE 620
Cdd:TIGR01612 1333 DAQKHNSDINLYLNEIANIYNIlkLNKIKKIIDEVKEYTKEIEENNKNIkDELDKSEKLIK 1393
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
87-328 1.81e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339    87 QLLQNAKRFTEQIQQQQFHLQQADNFPEAFSTEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKIt 166
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL- 784
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   167 KPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAhhqtipvQIGKEIE 246
Cdd:TIGR02169  785 EARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK-------SIEKEIE 857
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   247 KITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKvsaiVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSL 326
Cdd:TIGR02169  858 NLNGKKEELEEELEELEAALRDLESRLGDLKKE----RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933

                   ..
gi 100814339   327 TE 328
Cdd:TIGR02169  934 SE 935
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
110-628 2.35e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.96  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   110 DNFPEAFSTEVSKMRE-QLLKYQNEYNA-VKEREFHNQYRLNSLKEEKIIIVKEFEKITKpgeMEKKMKILRESTEELRK 187
Cdd:TIGR01612  655 DKIYSTIKSELSKIYEdDIDALYNELSSiVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN---METATVELHLSNIENKK 731
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   188 -EIMQKKLEIKN-----LREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEI-EKITRKKVEMEKKKI 260
Cdd:TIGR01612  732 nELLDIIVEIKKhihgeINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYnDQINIDNIKDEDAKQ 811
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   261 VLEQEvKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLlELARENEATSLTERGILDLNL---R 337
Cdd:TIGR01612  812 NYDKS-KEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEKIDS-EHEQFAELTNKIKAEISDDKLndyE 889
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   338 NSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRrELHKEVEVAK 417
Cdd:TIGR01612  890 KKFNDSKSLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESN-LIEKSYKDKF 968
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   418 RNLAQQKIiSEMESKLVEQQL----AEENKLLKEQENMKE-LVVNLLRMTQIKIDEKEQKSKDFlkaQQKYTNIVKEMKa 492
Cdd:TIGR01612  969 DNTLIDKI-NELDKAFKDASLndyeAKNNELIKYFNDLKAnLGKNKENMLYHQFDEKEKATNDI---EQKIEDANKNIP- 1043
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   493 kDLEIRIHKK------------------------KKCEI----YRRLREFAKLY---DTIRNERNKFVNLLHKAHQKVNE 541
Cdd:TIGR01612 1044 -NIEIAIHTSiyniideiekeigkniellnkeilEEAEInitnFNEIKEKLKHYnfdDFGKEENIKYADEINKIKDDIKN 1122
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   542 IKERHKMSLNELEILRNSAVS--QERKLQNSMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMI 619
Cdd:TIGR01612 1123 LDQKIDHHIKALEEIKKKSENyiDEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEI 1202

                   ....*....
gi 100814339   620 EEEMVQLRK 628
Cdd:TIGR01612 1203 EKDKTSLEE 1211
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
503-788 2.36e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 2.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 503 KKCEIYRRLREFAKLYDtirneRNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKLQNSMLKHANNVTIRE 582
Cdd:COG1196  210 EKAERYRELKEELKELE-----AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 583 SMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKRYEKAVQHRNESGVQLIEREEEICIFYEKINIQE 662
Cdd:COG1196  285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 663 KMKLNGEIEIHLLEEKIQFLKMKIAEKQRQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGENRArf 742
Cdd:COG1196  365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE-- 442
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 100814339 743 lpgkdlTEKEMIQKLDKLELQLAKKEEKLLEKDFIYEQVSRLTDRL 788
Cdd:COG1196  443 ------ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
118-455 2.78e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.65  E-value: 2.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  118 TEVSKMREQLLKYQNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQKKLeik 197
Cdd:pfam05557 149 SEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLL--- 225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  198 nLREDLASKQKQLLKEQKELEELLGHQVV---LKDEVAHHQTIPVQIGKEI---EKITRKKVEMEKKKIVLEQEVKTLND 271
Cdd:pfam05557 226 -LKEEVEDLKRKLEREEKYREEAATLELEkekLEQELQSWVKLAQDTGLNLrspEDLSRRIEQLQQREIVLKEENSSLTS 304
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  272 SLKKVENKVSAIVDEKENVIKEVEGkralLEIKEREHNQLVKLL-----------------------ELARENEATSLTE 328
Cdd:pfam05557 305 SARQLEKARRELEQELAQYLKKIED----LNKKLKRHKALVRRLqrrvllltkerdgyrailesydkELTMSNYSPQLLE 380
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  329 RgildLNLRNSLIDKQNYHDELSRKQREK-ERDFRNLRKMELLLKVSWDALRQTQALHQR---------LLLEMEAIPKD 398
Cdd:pfam05557 381 R----IEEAEDMTQKMQAHNEEMEAQLSVaEEELGGYKQQAQTLERELQALRQQESLADPsyskeevdsLRRKLETLELE 456
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 100814339  399 DSTLSERRRELhkEVEVAKRNLAQQKIISEME---------SKLVEQQLAEENKLLKEQENMKELV 455
Cdd:pfam05557 457 RQRLREQKNEL--EMELERRCLQGDYDPKKTKvlhlsmnpaAEAYQQRKNQLEKLQAEIERLKRLL 520
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
169-343 4.35e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 4.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 169 GEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLgHQVVLKDEVAHHQTIpVQIGKEIEKI 248
Cdd:PRK00409 512 GEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEE-DKLLEEAEKEAQQAI-KEAKKEADEI 589
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 249 TRKKVEMEKKKIV------LEQEVKTLNDSLKKVENKVsaiVDEKENVIKEVEGKRalleIKEREHNQLVKLLELARENE 322
Cdd:PRK00409 590 IKELRQLQKGGYAsvkaheLIEARKRLNKANEKKEKKK---KKQKEKQEELKVGDE----VKYLSLGQKGEVLSIPDDKE 662
                        170       180
                 ....*....|....*....|.
gi 100814339 323 ATslTERGILDLNLRNSLIDK 343
Cdd:PRK00409 663 AI--VQAGIMKMKVPLSDLEK 681
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
120-453 5.26e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 5.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   120 VSKMREQLLKYQNEYNAVKEREfhnqYRLNSLKEEKIiivKEFEKITKPGEMEKKMKILRESTEELRKEIMQKKLEIknL 199
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENI----ERLDLIIDEKR---QQLERLRREREKAERYQALLKEKREYEGYELLKEKEA--L 235
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   200 REDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKITRKKVEMEKKKIV--------LEQEVKTLND 271
Cdd:TIGR02169  236 ERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGeleaeiasLERSIAEKER 315
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   272 SLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELS 351
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339   352 RKQREKERDFRNLRKMELLLKVSWDALRQTQAlhqrlllEMEAIPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMES 431
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNA-------AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
                          330       340
                   ....*....|....*....|..
gi 100814339   432 KLVEQQLAEENKLLKEQENMKE 453
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQR 490
PRK12704 PRK12704
phosphodiesterase; Provisional
147-299 5.42e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.53  E-value: 5.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 147 RLNSLKEEKIIIVKEfEKITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVV 226
Cdd:PRK12704  50 EAEAIKKEALLEAKE-EIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEK 128
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 100814339 227 LKDEVahhQTIPVQIGKEIEKITRKKVEmEKKKIVLEQeVKtlndslKKVENKVSAIVDEKENVIKEVEGKRA 299
Cdd:PRK12704 129 KEEEL---EELIEEQLQELERISGLTAE-EAKEILLEK-VE------EEARHEAAVLIKEIEEEAKEEADKKA 190
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
170-329 5.79e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.52  E-value: 5.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 170 EMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIpvqigKEIEKIT 249
Cdd:COG1579   21 RLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNN-----KEYEALQ 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 250 RKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELARENEATSLTER 329
Cdd:COG1579   96 KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE 175
PRK01156 PRK01156
chromosome segregation protein; Provisional
160-777 9.51e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 39.88  E-value: 9.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 160 KEFEKITKPGEMEKKMKILRESTEELRKEIMqkklEIKNLREDLASKQKQLLKEQKELEEllghqvvlkDEVAHHQTIPv 239
Cdd:PRK01156 153 KILDEILEINSLERNYDKLKDVIDMLRAEIS----NIDYLEEKLKSSNLELENIKKQIAD---------DEKSHSITLK- 218
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 240 qigkEIEKITRKKVEMEKKKIVLEQEVKTLNdSLKKVENKVsaivdekENVIKEVEGKRALLEIKEREHNQLVKLLELAR 319
Cdd:PRK01156 219 ----EIERLSIEYNNAMDDYNNLKSALNELS-SLEDMKNRY-------ESEIKTAESDLSMELEKNNYYKELEERHMKII 286
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 320 ENEATSLTERGILDLNLRNSLIDKQNYhdeLSRKQREKERDFRNLRKMELLLKVSWDALRQTQalhqrlllEMEAIPKDD 399
Cdd:PRK01156 287 NDPVYKNRNYINDYFKYKNDIENKKQI---LSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKS--------RYDDLNNQI 355
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 400 STLserrRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRMTQIKIDEKEQKSKDFlkA 479
Cdd:PRK01156 356 LEL----EGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSL--N 429
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 480 QQKYTNIVKEMKAKDLEIRIHKKKKCEIY-RRLREfaklyDTIRNERNKFVNLLHKAHQKVNEIkerhkmslnELEIlrn 558
Cdd:PRK01156 430 QRIRALRENLDELSRNMEMLNGQSVCPVCgTTLGE-----EKSNHIINHYNEKKSRLEEKIREI---------EIEV--- 492
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 559 SAVSQERKLQNSMLKHANNVTIR---------ESMQNDVRKIVSKLQEMKEkKEAQLNNIDRLANTITMieEEMVQLRKR 629
Cdd:PRK01156 493 KDIDEKIVDLKKRKEYLESEEINksineynkiESARADLEDIKIKINELKD-KHDKYEEIKNRYKSLKL--EDLDSKRTS 569
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 630 YEKAVQHR------------NESGVQL---IEREEEICIFYEKIN-IQEKMKLNGEIEIHLLEEK---IQFLKMKIAEKQ 690
Cdd:PRK01156 570 WLNALAVIslidietnrsrsNEIKKQLndlESRLQEIEIGFPDDKsYIDKSIREIENEANNLNNKyneIQENKILIEKLR 649
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339 691 RQICVTQKLLPAKRSLDADLAVLQIQFSQCTDRIKDLEKQFVKPDGEnrarfLPGKDLTEKEMIQKLDKLELQLAKKEEK 770
Cdd:PRK01156 650 GKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKAN-----RARLESTIEILRTRINELSDRINDINET 724

                 ....*..
gi 100814339 771 LLEKDFI 777
Cdd:PRK01156 725 LESMKKI 731
COG5022 COG5022
Myosin heavy chain [General function prediction only];
200-496 9.66e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 40.06  E-value: 9.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  200 REDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEIEKiTRKKVEMEKKKIVLEQEVKTLNDSLKKVE-- 277
Cdd:COG5022   809 RKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLK-AKKRFSLLKKETIYLQSAQRVELAERQLQel 887
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  278 -------NKVSAIVDEKENVIKEVEGKRALLEIKEREHnQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDEL 350
Cdd:COG5022   888 kidvksiSSLKLVNLELESEIIELKKSLSSDLIENLEF-KTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKL 966
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 100814339  351 SRKQREKERDFRNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDSTLSERRRelhkevEVAKRNLAQQKIISEME 430
Cdd:COG5022   967 KETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPV------EVAELQSASKIISSEST 1040
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 100814339  431 SKLVEQQLAE-ENKLLKEQENMKElvvnllRMTQIKIDEKEQKSKDFLKAQQKYT-NIVKEMKAKDLE 496
Cdd:COG5022  1041 ELSILKPLQKlKGLLLLENNQLQA------RYKALKLRRENSLLDDKQLYQLESTeNLLKTINVKDLE 1102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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