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Conserved domains on  [gi|13162287|ref|NP_077045|]
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D-dopachrome decarboxylase [Rattus norvegicus]

Protein Classification

tautomerase family protein; 4-oxalocrotonate tautomerase family protein( domain architecture ID 10471872)

tautomerase family protein similar to Homo sapiens macrophage migration inhibitory factor and D-dopachrome decarboxylase-like protein; 4-oxalocrotonate tautomerase family protein such as 4-oxalocrotonate tautomerase, also called 2-hydroxymuconate tautomerase, which catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MIF pfam01187
Macrophage migration inhibitory factor (MIF);
2-116 1.54e-64

Macrophage migration inhibitory factor (MIF);


:

Pssm-ID: 395945  Cd Length: 114  Bit Score: 191.11  E-value: 1.54e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13162287     2 PFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLISSIGVVGtAEQNRSHSSSF 81
Cdd:pfam01187   1 PMFTIDTNLPANSVPAGLEKRLTAALAKALGKPADRIAVHIRPGQAMVFGGSTDPCAVCSIKSIGVVG-AEQNRSHSALL 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 13162287    82 FKFLTEELSLDQDRIIIRFFPLEPWQIGKKGTVMT 116
Cdd:pfam01187  80 FKFLTKELGLPKDRIYIRFFDLEAAQVGFNGTTFA 114
 
Name Accession Description Interval E-value
MIF pfam01187
Macrophage migration inhibitory factor (MIF);
2-116 1.54e-64

Macrophage migration inhibitory factor (MIF);


Pssm-ID: 395945  Cd Length: 114  Bit Score: 191.11  E-value: 1.54e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13162287     2 PFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLISSIGVVGtAEQNRSHSSSF 81
Cdd:pfam01187   1 PMFTIDTNLPANSVPAGLEKRLTAALAKALGKPADRIAVHIRPGQAMVFGGSTDPCAVCSIKSIGVVG-AEQNRSHSALL 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 13162287    82 FKFLTEELSLDQDRIIIRFFPLEPWQIGKKGTVMT 116
Cdd:pfam01187  80 FKFLTKELGLPKDRIYIRFFDLEAAQVGFNGTTFA 114
 
Name Accession Description Interval E-value
MIF pfam01187
Macrophage migration inhibitory factor (MIF);
2-116 1.54e-64

Macrophage migration inhibitory factor (MIF);


Pssm-ID: 395945  Cd Length: 114  Bit Score: 191.11  E-value: 1.54e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13162287     2 PFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLISSIGVVGtAEQNRSHSSSF 81
Cdd:pfam01187   1 PMFTIDTNLPANSVPAGLEKRLTAALAKALGKPADRIAVHIRPGQAMVFGGSTDPCAVCSIKSIGVVG-AEQNRSHSALL 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 13162287    82 FKFLTEELSLDQDRIIIRFFPLEPWQIGKKGTVMT 116
Cdd:pfam01187  80 FKFLTKELGLPKDRIYIRFFDLEAAQVGFNGTTFA 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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