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Conserved domains on  [gi|32307109|ref|NP_542181|]
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WAP four-disulfide core domain protein 3 precursor [Homo sapiens]

Protein Classification

WAP domain-containing protein( domain architecture ID 10442762)

WAP domain-containing protein similar to whey acidic protein (WAP) that could be a protease inhibitor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 75-113 8.32e-04

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 36.25  E-value: 8.32e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 32307109    75 DCPRVIRKQSCLKRCITDETCPGVKKCCTLGCNKSCVVP 113
Cdd:pfam00095   4 CCPRLGARGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 29-67 2.03e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.09  E-value: 2.03e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 32307109    29 KEGECPPHKNP--CKELCQGDELCPAEQKCCTTGCGRICRD 67
Cdd:pfam00095   1 KPGCCPRLGARgcCRSCCSSDDDCPGRQKCCSNGCGSVCVP 41
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 168-206 2.22e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.09  E-value: 2.22e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 32307109   168 GDCPKVLV-GLCIVGCVMDENCQAGEKCCKSGCGRFCVPP 206
Cdd:pfam00095   3 GCCPRLGArGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 124-159 6.78e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 33.55  E-value: 6.78e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 32307109   124 GECPA--DPLPCEELCDGDASCPQGHKCCSTGCGRTCL 159
Cdd:pfam00095   3 GCCPRlgARGCCRSCCSSDDDCPGRQKCCSNGCGSVCV 40
 
Name Accession Description Interval E-value
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 75-113 8.32e-04

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 36.25  E-value: 8.32e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 32307109    75 DCPRVIRKQSCLKRCITDETCPGVKKCCTLGCNKSCVVP 113
Cdd:pfam00095   4 CCPRLGARGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 29-67 2.03e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.09  E-value: 2.03e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 32307109    29 KEGECPPHKNP--CKELCQGDELCPAEQKCCTTGCGRICRD 67
Cdd:pfam00095   1 KPGCCPRLGARgcCRSCCSSDDDCPGRQKCCSNGCGSVCVP 41
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 168-206 2.22e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.09  E-value: 2.22e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 32307109   168 GDCPKVLV-GLCIVGCVMDENCQAGEKCCKSGCGRFCVPP 206
Cdd:pfam00095   3 GCCPRLGArGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 124-159 6.78e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 33.55  E-value: 6.78e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 32307109   124 GECPA--DPLPCEELCDGDASCPQGHKCCSTGCGRTCL 159
Cdd:pfam00095   3 GCCPRlgARGCCRSCCSSDDDCPGRQKCCSNGCGSVCV 40
 
Name Accession Description Interval E-value
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 75-113 8.32e-04

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 36.25  E-value: 8.32e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 32307109    75 DCPRVIRKQSCLKRCITDETCPGVKKCCTLGCNKSCVVP 113
Cdd:pfam00095   4 CCPRLGARGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 29-67 2.03e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.09  E-value: 2.03e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 32307109    29 KEGECPPHKNP--CKELCQGDELCPAEQKCCTTGCGRICRD 67
Cdd:pfam00095   1 KPGCCPRLGARgcCRSCCSSDDDCPGRQKCCSNGCGSVCVP 41
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 168-206 2.22e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.09  E-value: 2.22e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 32307109   168 GDCPKVLV-GLCIVGCVMDENCQAGEKCCKSGCGRFCVPP 206
Cdd:pfam00095   3 GCCPRLGArGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 124-159 6.78e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 33.55  E-value: 6.78e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 32307109   124 GECPA--DPLPCEELCDGDASCPQGHKCCSTGCGRTCL 159
Cdd:pfam00095   3 GCCPRlgARGCCRSCCSSDDDCPGRQKCCSNGCGSVCV 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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