phosphoinositide 3-kinase adapter protein 1 [Homo sapiens]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
DBB | pfam14545 | Dof, BCAP, and BANK (DBB) motif,; The DBB domain is named from the Drosophila (Downstream of ... |
180-318 | 6.81e-67 | |||
Dof, BCAP, and BANK (DBB) motif,; The DBB domain is named from the Drosophila (Downstream of FGFR - Dof, also known as Heartbroken or Stumps) protein, the BANKS and BCAP, both signalling in B-cell pathway, proteins. This domain defines a minimal region required for mediating Dof dimerization. Since this domain can interact both with itself and with a region in the C-terminal part of the molecule, it may mediate either intermolecular or intramolecular interactions. Mutants lacking this domain disrupt FGFR signal transduction and fibroblast growth-factor signalling. The DBB domain of BCAP mediates BCAP TIR dimerization and negatively regulates TLR signalling. : Pssm-ID: 464205 Cd Length: 139 Bit Score: 218.23 E-value: 6.81e-67
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TIR_3 | pfam18567 | Toll/interleukin-1 receptor domain; This is a Toll/interleukin-1 receptor (TIR) domain found ... |
11-141 | 8.17e-59 | |||
Toll/interleukin-1 receptor domain; This is a Toll/interleukin-1 receptor (TIR) domain found in the N-terminal region of B-cell adaptor for phosphoinositide 3-kinase (BCAP). BCAP functions in linking the B-cell receptor (BCR) and the co-receptor CD19 to the activation of PI3K via interaction with the SH2 domains on the regulatory p85 subunit. BCAP TIR associates with the MAL/TIRAP adaptor and the TIR domains of Toll-like receptors (TLRs). : Pssm-ID: 436583 Cd Length: 128 Bit Score: 195.91 E-value: 8.17e-59
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Name | Accession | Description | Interval | E-value | |||
DBB | pfam14545 | Dof, BCAP, and BANK (DBB) motif,; The DBB domain is named from the Drosophila (Downstream of ... |
180-318 | 6.81e-67 | |||
Dof, BCAP, and BANK (DBB) motif,; The DBB domain is named from the Drosophila (Downstream of FGFR - Dof, also known as Heartbroken or Stumps) protein, the BANKS and BCAP, both signalling in B-cell pathway, proteins. This domain defines a minimal region required for mediating Dof dimerization. Since this domain can interact both with itself and with a region in the C-terminal part of the molecule, it may mediate either intermolecular or intramolecular interactions. Mutants lacking this domain disrupt FGFR signal transduction and fibroblast growth-factor signalling. The DBB domain of BCAP mediates BCAP TIR dimerization and negatively regulates TLR signalling. Pssm-ID: 464205 Cd Length: 139 Bit Score: 218.23 E-value: 6.81e-67
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TIR_3 | pfam18567 | Toll/interleukin-1 receptor domain; This is a Toll/interleukin-1 receptor (TIR) domain found ... |
11-141 | 8.17e-59 | |||
Toll/interleukin-1 receptor domain; This is a Toll/interleukin-1 receptor (TIR) domain found in the N-terminal region of B-cell adaptor for phosphoinositide 3-kinase (BCAP). BCAP functions in linking the B-cell receptor (BCR) and the co-receptor CD19 to the activation of PI3K via interaction with the SH2 domains on the regulatory p85 subunit. BCAP TIR associates with the MAL/TIRAP adaptor and the TIR domains of Toll-like receptors (TLRs). Pssm-ID: 436583 Cd Length: 128 Bit Score: 195.91 E-value: 8.17e-59
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Name | Accession | Description | Interval | E-value | |||
DBB | pfam14545 | Dof, BCAP, and BANK (DBB) motif,; The DBB domain is named from the Drosophila (Downstream of ... |
180-318 | 6.81e-67 | |||
Dof, BCAP, and BANK (DBB) motif,; The DBB domain is named from the Drosophila (Downstream of FGFR - Dof, also known as Heartbroken or Stumps) protein, the BANKS and BCAP, both signalling in B-cell pathway, proteins. This domain defines a minimal region required for mediating Dof dimerization. Since this domain can interact both with itself and with a region in the C-terminal part of the molecule, it may mediate either intermolecular or intramolecular interactions. Mutants lacking this domain disrupt FGFR signal transduction and fibroblast growth-factor signalling. The DBB domain of BCAP mediates BCAP TIR dimerization and negatively regulates TLR signalling. Pssm-ID: 464205 Cd Length: 139 Bit Score: 218.23 E-value: 6.81e-67
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TIR_3 | pfam18567 | Toll/interleukin-1 receptor domain; This is a Toll/interleukin-1 receptor (TIR) domain found ... |
11-141 | 8.17e-59 | |||
Toll/interleukin-1 receptor domain; This is a Toll/interleukin-1 receptor (TIR) domain found in the N-terminal region of B-cell adaptor for phosphoinositide 3-kinase (BCAP). BCAP functions in linking the B-cell receptor (BCR) and the co-receptor CD19 to the activation of PI3K via interaction with the SH2 domains on the regulatory p85 subunit. BCAP TIR associates with the MAL/TIRAP adaptor and the TIR domains of Toll-like receptors (TLRs). Pssm-ID: 436583 Cd Length: 128 Bit Score: 195.91 E-value: 8.17e-59
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Blast search parameters | ||||
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