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Conserved domains on  [gi|46240864|ref|NP_996879|]
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sperm-associated antigen 17 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PapD-like super family cl20768
Flagellar-associated PapD-like; This domain is a putative PapD periplasmic pilus chaperone ...
 2076-2180 3.93e-11

Flagellar-associated PapD-like; This domain is a putative PapD periplasmic pilus chaperone protein family.


The actual alignment was detected with superfamily member pfam14874:

Pssm-ID: 373355  Cd Length: 102  Bit Score: 61.72  E-value: 3.93e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46240864   2076 FHLLPSSVKFGVLKEGHTYATVVKLKNVGVDFCRFKVKQPP-PSTGLKVTYKPGPVAAGMQTELNIELFATAvgEDGakg 2154
Cdd:pfam14874    4 LEVSPRVVHFGGVLPGNRYALTVRLTNTSTVPCRYRVRVPAvPKPFLSVEYPHQFVAPGLTTEAQVELSGTQ--PPG--- 78

                           90       100
                   ....*....|....*....|....*.
gi 46240864   2155 sAHISHnIEIMTEHEVLFLPVEATVL 2180
Cdd:pfam14874   79 -VMDSS-LSVTHEGGIVEVNVRAETT 102
Leo1 super family cl04368
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 248-346 3.10e-03

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


The actual alignment was detected with superfamily member pfam04004:

Pssm-ID: 461126  Cd Length: 163  Bit Score: 40.64  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46240864    248 IKISSENYEPlQTHLAAVNQQQEVLLQsEDLEAEKLKKENAIKelktfWKYlepVLNNEKPETNlfdvARleyMVKaadf 327
Cdd:pfam04004    9 LSIEPKPFDP-ETFEPEVDEESEVLDE-EGRFSIKLTVENTIR-----WRY---SPDTGIKESN----AR---IVR---- 67

                           90
                   ....*....|....*....
gi 46240864    328 psdWSDGEMMLKLGTDIFE 346
Cdd:pfam04004   68 ---WSDGSLSLQLGDEHFD 83
 
Name Accession Description Interval E-value
PapD-like pfam14874
Flagellar-associated PapD-like; This domain is a putative PapD periplasmic pilus chaperone ...
 2076-2180 3.93e-11

Flagellar-associated PapD-like; This domain is a putative PapD periplasmic pilus chaperone protein family.


Pssm-ID: 373355  Cd Length: 102  Bit Score: 61.72  E-value: 3.93e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46240864   2076 FHLLPSSVKFGVLKEGHTYATVVKLKNVGVDFCRFKVKQPP-PSTGLKVTYKPGPVAAGMQTELNIELFATAvgEDGakg 2154
Cdd:pfam14874    4 LEVSPRVVHFGGVLPGNRYALTVRLTNTSTVPCRYRVRVPAvPKPFLSVEYPHQFVAPGLTTEAQVELSGTQ--PPG--- 78

                           90       100
                   ....*....|....*....|....*.
gi 46240864   2155 sAHISHnIEIMTEHEVLFLPVEATVL 2180
Cdd:pfam14874   79 -VMDSS-LSVTHEGGIVEVNVRAETT 102
Leo1 pfam04004
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 248-346 3.10e-03

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


Pssm-ID: 461126  Cd Length: 163  Bit Score: 40.64  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46240864    248 IKISSENYEPlQTHLAAVNQQQEVLLQsEDLEAEKLKKENAIKelktfWKYlepVLNNEKPETNlfdvARleyMVKaadf 327
Cdd:pfam04004    9 LSIEPKPFDP-ETFEPEVDEESEVLDE-EGRFSIKLTVENTIR-----WRY---SPDTGIKESN----AR---IVR---- 67

                           90
                   ....*....|....*....
gi 46240864    328 psdWSDGEMMLKLGTDIFE 346
Cdd:pfam04004   68 ---WSDGSLSLQLGDEHFD 83
 
Name Accession Description Interval E-value
PapD-like pfam14874
Flagellar-associated PapD-like; This domain is a putative PapD periplasmic pilus chaperone ...
 2076-2180 3.93e-11

Flagellar-associated PapD-like; This domain is a putative PapD periplasmic pilus chaperone protein family.


Pssm-ID: 373355  Cd Length: 102  Bit Score: 61.72  E-value: 3.93e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46240864   2076 FHLLPSSVKFGVLKEGHTYATVVKLKNVGVDFCRFKVKQPP-PSTGLKVTYKPGPVAAGMQTELNIELFATAvgEDGakg 2154
Cdd:pfam14874    4 LEVSPRVVHFGGVLPGNRYALTVRLTNTSTVPCRYRVRVPAvPKPFLSVEYPHQFVAPGLTTEAQVELSGTQ--PPG--- 78

                           90       100
                   ....*....|....*....|....*.
gi 46240864   2155 sAHISHnIEIMTEHEVLFLPVEATVL 2180
Cdd:pfam14874   79 -VMDSS-LSVTHEGGIVEVNVRAETT 102
Leo1 pfam04004
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 248-346 3.10e-03

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


Pssm-ID: 461126  Cd Length: 163  Bit Score: 40.64  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46240864    248 IKISSENYEPlQTHLAAVNQQQEVLLQsEDLEAEKLKKENAIKelktfWKYlepVLNNEKPETNlfdvARleyMVKaadf 327
Cdd:pfam04004    9 LSIEPKPFDP-ETFEPEVDEESEVLDE-EGRFSIKLTVENTIR-----WRY---SPDTGIKESN----AR---IVR---- 67

                           90
                   ....*....|....*....
gi 46240864    328 psdWSDGEMMLKLGTDIFE 346
Cdd:pfam04004   68 ---WSDGSLSLQLGDEHFD 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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