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Conserved domains on  [gi|46358066|ref|NP_996986|]
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SLP adapter and CSK-interacting membrane protein isoform 1 [Homo sapiens]

Protein Classification

SCIMP domain-containing protein( domain architecture ID 10633344)

SCIMP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SCIMP pfam15050
SCIMP protein; This family contains the SCIMP proteins which are a a transmembrane adaptor ...
 12-142 1.10e-95

SCIMP protein; This family contains the SCIMP proteins which are a a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.


:

Pssm-ID: 434419  Cd Length: 132  Bit Score: 271.69  E-value: 1.10e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358066    12 MSWWRNNFWIILAVAIIVVSVGLGLILYCVCKWQLRRGKKWEIAKPLKHKQVDEEKMYENVLNESPVQLPPLPPRNWPSL 91
Cdd:pfam15050   1 MSWWRNNFWIILAVAIIVVSVVLGLILYCVCRWQLRQGKKWEIAKPLKQNQRDEEKMYENVINQSPVQLPPLPPRGLPSP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 46358066    92 EDSSPQEAPSQPPATYSLVNKVKNKKTVSIPSYIEPEDDYDDVEIPANTEK 142
Cdd:pfam15050  81 EDSSPQETPSQPPATYSLVNKVRNKKTVSIPSYIEPEDDYDDVEIPANTES 131
 
Name Accession Description Interval E-value
SCIMP pfam15050
SCIMP protein; This family contains the SCIMP proteins which are a a transmembrane adaptor ...
 12-142 1.10e-95

SCIMP protein; This family contains the SCIMP proteins which are a a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.


Pssm-ID: 434419  Cd Length: 132  Bit Score: 271.69  E-value: 1.10e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358066    12 MSWWRNNFWIILAVAIIVVSVGLGLILYCVCKWQLRRGKKWEIAKPLKHKQVDEEKMYENVLNESPVQLPPLPPRNWPSL 91
Cdd:pfam15050   1 MSWWRNNFWIILAVAIIVVSVVLGLILYCVCRWQLRQGKKWEIAKPLKQNQRDEEKMYENVINQSPVQLPPLPPRGLPSP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 46358066    92 EDSSPQEAPSQPPATYSLVNKVKNKKTVSIPSYIEPEDDYDDVEIPANTEK 142
Cdd:pfam15050  81 EDSSPQETPSQPPATYSLVNKVRNKKTVSIPSYIEPEDDYDDVEIPANTES 131
 
Name Accession Description Interval E-value
SCIMP pfam15050
SCIMP protein; This family contains the SCIMP proteins which are a a transmembrane adaptor ...
 12-142 1.10e-95

SCIMP protein; This family contains the SCIMP proteins which are a a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.


Pssm-ID: 434419  Cd Length: 132  Bit Score: 271.69  E-value: 1.10e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358066    12 MSWWRNNFWIILAVAIIVVSVGLGLILYCVCKWQLRRGKKWEIAKPLKHKQVDEEKMYENVLNESPVQLPPLPPRNWPSL 91
Cdd:pfam15050   1 MSWWRNNFWIILAVAIIVVSVVLGLILYCVCRWQLRQGKKWEIAKPLKQNQRDEEKMYENVINQSPVQLPPLPPRGLPSP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 46358066    92 EDSSPQEAPSQPPATYSLVNKVKNKKTVSIPSYIEPEDDYDDVEIPANTEK 142
Cdd:pfam15050  81 EDSSPQETPSQPPATYSLVNKVRNKKTVSIPSYIEPEDDYDDVEIPANTES 131
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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