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Conserved domains on  [gi|57012996|sp|O75915|]
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RecName: Full=PRA1 family protein 3; AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 5; Short=ARL-6-interacting protein 5; Short=Aip-5; AltName: Full=Cytoskeleton-related vitamin A-responsive protein; AltName: Full=Dermal papilla-derived protein 11; AltName: Full=GTRAP3-18; AltName: Full=Glutamate transporter EAAC1-interacting protein; AltName: Full=JM5; AltName: Full=Prenylated Rab acceptor protein 2; AltName: Full=Protein JWa; AltName: Full=Putative MAPK-activating protein PM27

Protein Classification

PRA1 family protein( domain architecture ID 10505078)

prenylated Rab acceptor protein 1 (PRA1) family protein facilitates the delivery of Rab GTPases to the membrane by dissociating the Rab-GDI complex during vesicle trafficking

Gene Ontology:  GO:0016020|GO:0015031
PubMed:  16473601

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRA1 pfam03208
PRA1 family protein; This family includes the PRA1 (Prenylated rab acceptor) protein which is ...
 3-148 1.29e-38

PRA1 family protein; This family includes the PRA1 (Prenylated rab acceptor) protein which is a Rab guanine dissociation inhibitor (GDI) displacement factor. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18.


:

Pssm-ID: 460846  Cd Length: 141  Bit Score: 129.18  E-value: 1.29e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57012996     3 VNIAPLRAWDDFFPgSDRFARPdfRDISKWNNRVVSNLLYYQTNYLVVAAMMISIVGFLSPFNMILGGIVVVLVFTGFVW 82
Cdd:pfam03208   1 SQLAPRRPWSEFFD-SSRFSRP--RSFSEATSRVKRNLLYFRTNYFIVVLLLLFLSLLTHPLSLIVFLVVLAAWLFLYFL 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 57012996    83 AAHNKDVL-RRMKKRyptTFVMVVMLASYFLISMFGGVMVFVFGITFPLLLMFIHASLRLRNLKNKL 148
Cdd:pfam03208  78 RDEPLVIFgRTFSDR---VVLIGLLVVSVVLLFLTGVGSVLLWALGAGLLLVLLHASFRLRNDLFLD 141
 
Name Accession Description Interval E-value
PRA1 pfam03208
PRA1 family protein; This family includes the PRA1 (Prenylated rab acceptor) protein which is ...
 3-148 1.29e-38

PRA1 family protein; This family includes the PRA1 (Prenylated rab acceptor) protein which is a Rab guanine dissociation inhibitor (GDI) displacement factor. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18.


Pssm-ID: 460846  Cd Length: 141  Bit Score: 129.18  E-value: 1.29e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57012996     3 VNIAPLRAWDDFFPgSDRFARPdfRDISKWNNRVVSNLLYYQTNYLVVAAMMISIVGFLSPFNMILGGIVVVLVFTGFVW 82
Cdd:pfam03208   1 SQLAPRRPWSEFFD-SSRFSRP--RSFSEATSRVKRNLLYFRTNYFIVVLLLLFLSLLTHPLSLIVFLVVLAAWLFLYFL 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 57012996    83 AAHNKDVL-RRMKKRyptTFVMVVMLASYFLISMFGGVMVFVFGITFPLLLMFIHASLRLRNLKNKL 148
Cdd:pfam03208  78 RDEPLVIFgRTFSDR---VVLIGLLVVSVVLLFLTGVGSVLLWALGAGLLLVLLHASFRLRNDLFLD 141
 
Name Accession Description Interval E-value
PRA1 pfam03208
PRA1 family protein; This family includes the PRA1 (Prenylated rab acceptor) protein which is ...
 3-148 1.29e-38

PRA1 family protein; This family includes the PRA1 (Prenylated rab acceptor) protein which is a Rab guanine dissociation inhibitor (GDI) displacement factor. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18.


Pssm-ID: 460846  Cd Length: 141  Bit Score: 129.18  E-value: 1.29e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57012996     3 VNIAPLRAWDDFFPgSDRFARPdfRDISKWNNRVVSNLLYYQTNYLVVAAMMISIVGFLSPFNMILGGIVVVLVFTGFVW 82
Cdd:pfam03208   1 SQLAPRRPWSEFFD-SSRFSRP--RSFSEATSRVKRNLLYFRTNYFIVVLLLLFLSLLTHPLSLIVFLVVLAAWLFLYFL 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 57012996    83 AAHNKDVL-RRMKKRyptTFVMVVMLASYFLISMFGGVMVFVFGITFPLLLMFIHASLRLRNLKNKL 148
Cdd:pfam03208  78 RDEPLVIFgRTFSDR---VVLIGLLVVSVVLLFLTGVGSVLLWALGAGLLLVLLHASFRLRNDLFLD 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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