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Conserved domains on  [gi|1084827067|gb|OGQ60790|]
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type II secretion system protein E [Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_53_8]

Protein Classification

GspE/PulE family protein( domain architecture ID 11457962)

GspE/PulE family protein similar to type II secretion system protein E, an essential component of type II systems, and to type IV pilus assembly ATPase PilB

CATH:  3.40.50.300
PubMed:  11226268
SCOP:  4005829|4004682

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
82-597 0e+00

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 709.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  82 LTEDMITEAIAAEVGLPYKKIDPLKINADVATSfIPRPFAQKHLIVPIEEKDKVVTVALADPYNLDAIEGLQSTGKVKLK 161
Cdd:COG2804    48 VTEELLAEALAEQLGLPFVDLDELEIDPEVLEL-LPEELARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVE 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 162 LVLASKSDILMIIREFYGFRYSVGAAEKEVRKDteLSNLEQYVKlkgAVELDATDQHVINAVEYLLHYAYEQRASDIHIE 241
Cdd:COG2804   127 PVVATESDIERALDRLYGSESSIEELLEELAED--LTSEEEDLE---DLLEEADDAPVVRLVNAILEDAIKEGASDIHIE 201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 242 PKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDGRIKTSFKDKEVELRVSTLPTAFGEKVVIR 321
Cdd:COG2804   202 PYEKRLRVRFRIDGVLREVLRLPKSLAPALVSRIKIMANLDIAERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLR 281
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 322 IFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQV 401
Cdd:COG2804   282 ILDKSAALLDLEQLGFSPDQLERLRRLIRRPHGIILVTGPTGSGKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQV 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 402 GVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTII 481
Cdd:COG2804   362 QVNPKIGLTFASALRSILRQDPDVIMVGEIRDLETAEIAVQAALTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLL 441
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 482 GIAAQRLVRKICKSCSKERLLTADEVEYLRIRKD--REYKVCYGEGCNECRGTGYRGRVAIYELLEFTDKIRAFVTASTD 559
Cdd:COG2804   442 GVLAQRLVRRLCPHCKEPYEPDPEELERLGLPPEelAPLTFYRGVGCEHCNGTGYKGRTGIYELLVIDDELRELIAEGAS 521
                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1084827067 560 LAAVGKAAREQGMSSLRESALRKMLGGITTYEEVISVT 597
Cdd:COG2804   522 AAELREAARKEGMRTLREDGLEKVLQGITTLEEVLRVT 559
 
Name Accession Description Interval E-value
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
82-597 0e+00

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 709.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  82 LTEDMITEAIAAEVGLPYKKIDPLKINADVATSfIPRPFAQKHLIVPIEEKDKVVTVALADPYNLDAIEGLQSTGKVKLK 161
Cdd:COG2804    48 VTEELLAEALAEQLGLPFVDLDELEIDPEVLEL-LPEELARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVE 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 162 LVLASKSDILMIIREFYGFRYSVGAAEKEVRKDteLSNLEQYVKlkgAVELDATDQHVINAVEYLLHYAYEQRASDIHIE 241
Cdd:COG2804   127 PVVATESDIERALDRLYGSESSIEELLEELAED--LTSEEEDLE---DLLEEADDAPVVRLVNAILEDAIKEGASDIHIE 201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 242 PKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDGRIKTSFKDKEVELRVSTLPTAFGEKVVIR 321
Cdd:COG2804   202 PYEKRLRVRFRIDGVLREVLRLPKSLAPALVSRIKIMANLDIAERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLR 281
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 322 IFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQV 401
Cdd:COG2804   282 ILDKSAALLDLEQLGFSPDQLERLRRLIRRPHGIILVTGPTGSGKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQV 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 402 GVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTII 481
Cdd:COG2804   362 QVNPKIGLTFASALRSILRQDPDVIMVGEIRDLETAEIAVQAALTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLL 441
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 482 GIAAQRLVRKICKSCSKERLLTADEVEYLRIRKD--REYKVCYGEGCNECRGTGYRGRVAIYELLEFTDKIRAFVTASTD 559
Cdd:COG2804   442 GVLAQRLVRRLCPHCKEPYEPDPEELERLGLPPEelAPLTFYRGVGCEHCNGTGYKGRTGIYELLVIDDELRELIAEGAS 521
                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1084827067 560 LAAVGKAAREQGMSSLRESALRKMLGGITTYEEVISVT 597
Cdd:COG2804   522 AAELREAARKEGMRTLREDGLEKVLQGITTLEEVLRVT 559
type_II_gspE TIGR02533
type II secretion system protein E; This family describes GspE, the E protein of the type II ...
116-597 3.37e-176

type II secretion system protein E; This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 131585 [Multi-domain]  Cd Length: 486  Bit Score: 508.07  E-value: 3.37e-176
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 116 IPRPFAQKHLIVPIEEKDKVVTVALADPYNLDAIEGLQSTGKVKLKLVLASKSDILMIIREFYGfRYSVGAAE--KEVRK 193
Cdd:TIGR02533   4 LPIGFAKQSRVLPLSEHDGTLVVAVSDPLDLAALDEVRRLFGAPVQLIIATASEIDDAINSVYA-RTGSAAAQivEEIEG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 194 DTELSNLEQYVKLKGAVELDATDQHVINAVEYLLHYAYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVS 273
Cdd:TIGR02533  83 EDDLSALELDEPKIEDLLDLEDDAPVIRLVNSLLSRAVKERASDIHIEPFEKALVVRFRVDGVLRDVLSPPKKLHAALVS 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 274 RIKMLSRMDIAEKRKPQDGRIKTSFKDKEVELRVSTLPTAFGEKVVIRIFDPELLLQEVATLGFTPKEFEVFNAFLKKTF 353
Cdd:TIGR02533 163 RVKIMAKLNIAEKRLPQDGRISLRVGGRDIDIRVSTVPTSHGERVVMRLLDKTAVRLDLETLGMSPELLSRFERLIRRPH 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 354 GIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRD 433
Cdd:TIGR02533 243 GIILVTGPTGSGKTTTLYAALSRLNTPERNILTVEDPVEYQIEGIGQIQVNPKIGLTFAAGLRAILRQDPDIIMVGEIRD 322
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 434 AETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTIIGIAAQRLVRKICKSCSKERLLTADEVEYLRIR 513
Cdd:TIGR02533 323 LETAQIAIQASLTGHLVLSTLHTNDAAGAVTRLIDMGVEPFLLASSLLGVLAQRLVRRLCPHCKEPYEATPEEIALFGIS 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 514 KDREYKVCYGEGCNECRGTGYRGRVAIYELLEFTDKIRAFVTASTDLAAVGKAAREQGMSSLRESALRKMLGGITTYEEV 593
Cdd:TIGR02533 403 PEGPINLYRPVGCPHCNHTGYLGRTGIYELLIVDDDLRSLIHSRADEGEIKEIARAAGMRTLRDDGLRKVLAGITTIEEV 482

                  ....
gi 1084827067 594 ISVT 597
Cdd:TIGR02533 483 LRVT 486
PRK10436 PRK10436
hypothetical protein; Provisional
213-597 4.70e-130

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 388.90  E-value: 4.70e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 213 DATDQHVINAVEYLLHYAYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDG 292
Cdd:PRK10436   78 QEKDTPVAQLINQTLQSALQKRASDIHFEPAQNHYRIRLRIDGVLHPLPDPSPELGAALTARLKVLGNLDIAERRLPQDG 157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 293 RIKTSFKDKEVELRVSTLPTAFGEKVVIRIFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYS 372
Cdd:PRK10436  158 QFTVELAGNAYSFRIATLPCRGGEKVVLRLLQQVQQALDLETLGMTPAQLAQFRQALQQPQGLILVTGPTGSGKTVTLYS 237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 373 ALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLS 452
Cdd:PRK10436  238 ALQTLNTAQINICSVEDPVEIPLAGINQTQIHPKAGLTFQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVLS 317
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 453 TLHTNDAPTSITRLMDLGIPPFLINSTIIGIAAQRLVRKICKSCSKERLLTADEVEYLRIRKDREYKVCygeGCNECRgT 532
Cdd:PRK10436  318 TLHTNSTSETLVRLQQMGIARWMLASALKLVIAQRLVRKLCPHCRQQASEPIHLPPNIWPGPLPHWQAV---GCEHCY-H 393
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1084827067 533 GYRGRVAIYELLEFTDKIRAFVTASTDLAAVGKAAREQGMSSLRESALRKMLGGITTYEEVISVT 597
Cdd:PRK10436  394 GYYGRTALFEVLPITPVLQQAIASNASPEELETHARQQGMTTLFENGLLAVEQGLTTLEELYRVL 458
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
230-491 2.65e-113

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 338.88  E-value: 2.65e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 230 AYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDGRIKTSFKDKEVELRVST 309
Cdd:pfam00437   7 ALDEGASDIHVEPPERIVWIRFRVDGVLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPLRIGGKGVRVRVST 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 310 LPTAFGEKVVIRIFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIED 389
Cdd:pfam00437  87 LPTAGGEKLVIRLLDPSNVALSLDELGMTGAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELNTRDENIVTVED 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 390 PIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDL 469
Cdd:pfam00437 167 PVEIQLEGINQVQLNARAGVTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSAAGALTRLQDM 246
                         250       260
                  ....*....|....*....|..
gi 1084827067 470 GIPPFLINSTIIGIAAQRLVRK 491
Cdd:pfam00437 247 GVPPFELASSLLLVIAQRLVRK 268
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
224-489 8.39e-99

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 301.67  E-value: 8.39e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 224 EYLLHYAYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDGRIKTSFKDKEV 303
Cdd:NF041000    1 EELIEEAIELRASDIHFLPREDGYQIKFRIGGGLIPYRELSLEEGQRLISYFKFLAGMDIGEKRRPQSGAFTYELNEQQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 304 ELRVSTLPTAFG-EKVVIRIFDPElllQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTpEV 382
Cdd:NF041000   81 SLRLSTVGDFLGrESLVIRLLYQL---EQIKPQLFFPEQFQLLKQLLQRRSGLILFSGPTGSGKTTTMYSLARKLAL-NK 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 383 NIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTS 462
Cdd:NF041000  157 QVITIEDPVEIKEPNFLQLQVNEKAGMTYDTLLKAALRHRPDILIIGEIRDAETAKAAIRAALTGHLVLSTVHAKSAAGV 236
                         250       260
                  ....*....|....*....|....*..
gi 1084827067 463 ITRLMDLGIPPFLINSTIIGIAAQRLV 489
Cdd:NF041000  237 IYRLLELGISKEELEQTLIGISYQRLI 263
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
343-492 8.46e-85

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 261.27  E-value: 8.46e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 343 EVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQD 422
Cdd:cd01129     1 ARLRRLIKRPHGLILVTGPTGSGKTTTLYAMLRELNGPERNIITIEDPVEYQIPGINQSQVNEKIGLTFADALRAILRQD 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 423 PDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTIIGIAAQRLVRKI 492
Cdd:cd01129    81 PDIIMVGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGIEPFLLASALRGVIAQRLVGRT 150
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
354-431 1.16e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  354 GIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTI-------EDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDII 426
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIdgedileEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVL 82

                   ....*
gi 1084827067  427 MVGEI 431
Cdd:smart00382  83 ILDEI 87
 
Name Accession Description Interval E-value
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
82-597 0e+00

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 709.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  82 LTEDMITEAIAAEVGLPYKKIDPLKINADVATSfIPRPFAQKHLIVPIEEKDKVVTVALADPYNLDAIEGLQSTGKVKLK 161
Cdd:COG2804    48 VTEELLAEALAEQLGLPFVDLDELEIDPEVLEL-LPEELARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVE 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 162 LVLASKSDILMIIREFYGFRYSVGAAEKEVRKDteLSNLEQYVKlkgAVELDATDQHVINAVEYLLHYAYEQRASDIHIE 241
Cdd:COG2804   127 PVVATESDIERALDRLYGSESSIEELLEELAED--LTSEEEDLE---DLLEEADDAPVVRLVNAILEDAIKEGASDIHIE 201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 242 PKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDGRIKTSFKDKEVELRVSTLPTAFGEKVVIR 321
Cdd:COG2804   202 PYEKRLRVRFRIDGVLREVLRLPKSLAPALVSRIKIMANLDIAERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLR 281
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 322 IFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQV 401
Cdd:COG2804   282 ILDKSAALLDLEQLGFSPDQLERLRRLIRRPHGIILVTGPTGSGKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQV 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 402 GVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTII 481
Cdd:COG2804   362 QVNPKIGLTFASALRSILRQDPDVIMVGEIRDLETAEIAVQAALTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLL 441
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 482 GIAAQRLVRKICKSCSKERLLTADEVEYLRIRKD--REYKVCYGEGCNECRGTGYRGRVAIYELLEFTDKIRAFVTASTD 559
Cdd:COG2804   442 GVLAQRLVRRLCPHCKEPYEPDPEELERLGLPPEelAPLTFYRGVGCEHCNGTGYKGRTGIYELLVIDDELRELIAEGAS 521
                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1084827067 560 LAAVGKAAREQGMSSLRESALRKMLGGITTYEEVISVT 597
Cdd:COG2804   522 AAELREAARKEGMRTLREDGLEKVLQGITTLEEVLRVT 559
type_II_gspE TIGR02533
type II secretion system protein E; This family describes GspE, the E protein of the type II ...
116-597 3.37e-176

type II secretion system protein E; This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 131585 [Multi-domain]  Cd Length: 486  Bit Score: 508.07  E-value: 3.37e-176
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 116 IPRPFAQKHLIVPIEEKDKVVTVALADPYNLDAIEGLQSTGKVKLKLVLASKSDILMIIREFYGfRYSVGAAE--KEVRK 193
Cdd:TIGR02533   4 LPIGFAKQSRVLPLSEHDGTLVVAVSDPLDLAALDEVRRLFGAPVQLIIATASEIDDAINSVYA-RTGSAAAQivEEIEG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 194 DTELSNLEQYVKLKGAVELDATDQHVINAVEYLLHYAYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVS 273
Cdd:TIGR02533  83 EDDLSALELDEPKIEDLLDLEDDAPVIRLVNSLLSRAVKERASDIHIEPFEKALVVRFRVDGVLRDVLSPPKKLHAALVS 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 274 RIKMLSRMDIAEKRKPQDGRIKTSFKDKEVELRVSTLPTAFGEKVVIRIFDPELLLQEVATLGFTPKEFEVFNAFLKKTF 353
Cdd:TIGR02533 163 RVKIMAKLNIAEKRLPQDGRISLRVGGRDIDIRVSTVPTSHGERVVMRLLDKTAVRLDLETLGMSPELLSRFERLIRRPH 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 354 GIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRD 433
Cdd:TIGR02533 243 GIILVTGPTGSGKTTTLYAALSRLNTPERNILTVEDPVEYQIEGIGQIQVNPKIGLTFAAGLRAILRQDPDIIMVGEIRD 322
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 434 AETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTIIGIAAQRLVRKICKSCSKERLLTADEVEYLRIR 513
Cdd:TIGR02533 323 LETAQIAIQASLTGHLVLSTLHTNDAAGAVTRLIDMGVEPFLLASSLLGVLAQRLVRRLCPHCKEPYEATPEEIALFGIS 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 514 KDREYKVCYGEGCNECRGTGYRGRVAIYELLEFTDKIRAFVTASTDLAAVGKAAREQGMSSLRESALRKMLGGITTYEEV 593
Cdd:TIGR02533 403 PEGPINLYRPVGCPHCNHTGYLGRTGIYELLIVDDDLRSLIHSRADEGEIKEIARAAGMRTLRDDGLRKVLAGITTIEEV 482

                  ....
gi 1084827067 594 ISVT 597
Cdd:TIGR02533 483 LRVT 486
type_IV_pilB TIGR02538
type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus ...
41-597 2.07e-165

type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274186 [Multi-domain]  Cd Length: 564  Bit Score: 483.36  E-value: 2.07e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  41 LKKAQEQSYTSKRRGAVGEFIspaEVIAALNFsvpgttgrpLTEDMITEAIAAEVGLPYKKIDPLKINAdVATSFIPRPF 120
Cdd:TIGR02538  12 LTETQAQAALEEAQASGQPLV---QYLIQNGL---------LDPKQLAEFLSREFGVPLLDLNAFDPDA-LPVQLVSEEL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 121 AQKHLIVPIEEKDKVVTVALADPYNLDAIEGLQSTGKVKLKLVLASKSDILMIIREFYGFRYSVG-AAEKEVRKDTELSN 199
Cdd:TIGR02538  79 IQKHQALPLFKRGNTLFVAVSDPTNISALDDIRFATGLNVEVVIVEEDKLSALIEKYYGGSDSLAkELGDEDIGDLEELD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 200 LEQYV-KLKGAVELDAT--DQHVINAVEYLLHYAYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIK 276
Cdd:TIGR02538 159 VDAIDdEGPDDIEQDAVddDAPIVKFVNKILLDAIRKGASDIHFEPYEKSYRVRFRIDGILHEVAQPPLALANRIAARIK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 277 MLSRMDIAEKRKPQDGRIKTSF-KDKEVELRVSTLPTAFGEKVVIRIFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGI 355
Cdd:TIGR02538 239 VMSRLDIAEKRIPQDGRIKLKLsKSKAIDFRVSTLPTLFGEKVVLRILDSSAAQLDIDKLGFEPDQKALFLEAIHKPQGM 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAE 435
Cdd:TIGR02538 319 VLVTGPTGSGKTVSLYTALNILNTEEVNISTAEDPVEINLPGINQVNVNPKIGLTFAAALRSFLRQDPDIIMVGEIRDLE 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 436 TANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTIIGIAAQRLVRKICKSCSKERLLTADEVEYLRIRK- 514
Cdd:TIGR02538 399 TAEIAIKAAQTGHLVLSTLHTNDAPETLARLVNMGIAPFNIASSVNLIMAQRLARRLCSHCKAPEEVPAEALLELGFTQe 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 515 DREYKVCYG-EGCNECRGTGYRGRVAIYELLEFTDKIRAFVTASTDLAAVGKAAREQGMSSLRESALRKMLGGITTYEEV 593
Cdd:TIGR02538 479 DLADLKLYGpVGCDECSNTGYKGRVGIYEVMPMSEEIAELILKGGNALQIAELAQKEGMRTLRRSGLLKVKQGVTSLEEV 558

                  ....
gi 1084827067 594 ISVT 597
Cdd:TIGR02538 559 LRVT 562
PRK10436 PRK10436
hypothetical protein; Provisional
213-597 4.70e-130

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 388.90  E-value: 4.70e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 213 DATDQHVINAVEYLLHYAYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDG 292
Cdd:PRK10436   78 QEKDTPVAQLINQTLQSALQKRASDIHFEPAQNHYRIRLRIDGVLHPLPDPSPELGAALTARLKVLGNLDIAERRLPQDG 157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 293 RIKTSFKDKEVELRVSTLPTAFGEKVVIRIFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYS 372
Cdd:PRK10436  158 QFTVELAGNAYSFRIATLPCRGGEKVVLRLLQQVQQALDLETLGMTPAQLAQFRQALQQPQGLILVTGPTGSGKTVTLYS 237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 373 ALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLS 452
Cdd:PRK10436  238 ALQTLNTAQINICSVEDPVEIPLAGINQTQIHPKAGLTFQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVLS 317
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 453 TLHTNDAPTSITRLMDLGIPPFLINSTIIGIAAQRLVRKICKSCSKERLLTADEVEYLRIRKDREYKVCygeGCNECRgT 532
Cdd:PRK10436  318 TLHTNSTSETLVRLQQMGIARWMLASALKLVIAQRLVRKLCPHCRQQASEPIHLPPNIWPGPLPHWQAV---GCEHCY-H 393
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1084827067 533 GYRGRVAIYELLEFTDKIRAFVTASTDLAAVGKAAREQGMSSLRESALRKMLGGITTYEEVISVT 597
Cdd:PRK10436  394 GYYGRTALFEVLPITPVLQQAIASNASPEELETHARQQGMTTLFENGLLAVEQGLTTLEELYRVL 458
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
230-491 2.65e-113

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 338.88  E-value: 2.65e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 230 AYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDGRIKTSFKDKEVELRVST 309
Cdd:pfam00437   7 ALDEGASDIHVEPPERIVWIRFRVDGVLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPLRIGGKGVRVRVST 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 310 LPTAFGEKVVIRIFDPELLLQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIED 389
Cdd:pfam00437  87 LPTAGGEKLVIRLLDPSNVALSLDELGMTGAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELNTRDENIVTVED 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 390 PIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDL 469
Cdd:pfam00437 167 PVEIQLEGINQVQLNARAGVTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSAAGALTRLQDM 246
                         250       260
                  ....*....|....*....|..
gi 1084827067 470 GIPPFLINSTIIGIAAQRLVRK 491
Cdd:pfam00437 247 GVPPFELASSLLLVIAQRLVRK 268
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
224-489 8.39e-99

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 301.67  E-value: 8.39e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 224 EYLLHYAYEQRASDIHIEPKREKTVVRLRIDGVLHYIHTIPKPVHPSVVSRIKMLSRMDIAEKRKPQDGRIKTSFKDKEV 303
Cdd:NF041000    1 EELIEEAIELRASDIHFLPREDGYQIKFRIGGGLIPYRELSLEEGQRLISYFKFLAGMDIGEKRRPQSGAFTYELNEQQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 304 ELRVSTLPTAFG-EKVVIRIFDPElllQEVATLGFTPKEFEVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTpEV 382
Cdd:NF041000   81 SLRLSTVGDFLGrESLVIRLLYQL---EQIKPQLFFPEQFQLLKQLLQRRSGLILFSGPTGSGKTTTMYSLARKLAL-NK 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 383 NIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTS 462
Cdd:NF041000  157 QVITIEDPVEIKEPNFLQLQVNEKAGMTYDTLLKAALRHRPDILIIGEIRDAETAKAAIRAALTGHLVLSTVHAKSAAGV 236
                         250       260
                  ....*....|....*....|....*..
gi 1084827067 463 ITRLMDLGIPPFLINSTIIGIAAQRLV 489
Cdd:NF041000  237 IYRLLELGISKEELEQTLIGISYQRLI 263
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
343-492 8.46e-85

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 261.27  E-value: 8.46e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 343 EVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQD 422
Cdd:cd01129     1 ARLRRLIKRPHGLILVTGPTGSGKTTTLYAMLRELNGPERNIITIEDPVEYQIPGINQSQVNEKIGLTFADALRAILRQD 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 423 PDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLGIPPFLINSTIIGIAAQRLVRKI 492
Cdd:cd01129    81 PDIIMVGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGIEPFLLASALRGVIAQRLVGRT 150
PilT COG2805
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ...
223-595 6.36e-62

Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];


Pssm-ID: 442056  Cd Length: 342  Bit Score: 208.02  E-value: 6.36e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 223 VEYLLHYAYEQRASDIHIEPKRektVVRLRIDGVLHYIHTipKPVHPSVVSRIkMLSRMDIAEKRKPQDGR-IKTSFkdk 301
Cdd:COG2805     5 LDELLKLAVEQGASDLHLTVGS---PPMLRIDGELVPLDD--PPLTPEDLEAL-LKEILTEEQRERLEEEGeLDFSY--- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 302 EVE----LRVSTLPTAFGEKVVIRIFDPELLlqEVATLGFTPkefeVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTL 377
Cdd:COG2805    76 SLPglgrFRVNIFRQRGGVAAVLRLIPSEIP--TLEELGLPP----VLKELAELPRGLVLVTGPTGSGKSTTLAAMIDYI 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 378 -STPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMD---FASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLST 453
Cdd:COG2805   150 nETRAKHIITIEDPIEFVHKHKKSLINQREVGRDtpsFANALRAALREDPDVILVGEMRDLETIEAALTAAETGHLVFAT 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 454 LHTNDAPTSITRLMDLgIPP-------FLINSTIIGIAAQRLVRKIckscskerlltadeveylrirkdreykvcygEGc 526
Cdd:COG2805   230 LHTNSAAQTIDRIIDV-FPPeeqaqirSQLAESLRGVISQRLLPRA-------------------------------DG- 276
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1084827067 527 necrgtgyRGRVAIYELLEFTDKIRAFV--TASTDLAAVGKAAREQGMSSLRESALRKMLGGITTYEEVIS 595
Cdd:COG2805   277 --------GGRVAAREILVNTPAVRNLIreGKTHQIPSLIQTGKKLGMQTMDQSLAELVKEGLITEETALA 339
pilT_fam TIGR01420
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to ...
226-491 1.00e-50

pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility]


Pssm-ID: 273613  Cd Length: 343  Bit Score: 178.28  E-value: 1.00e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 226 LLHYAYEQRASDIHIepkREKTVVRLRIDGVLHYIhTIPKPVHPSVVSRIK-MLSrmDIAEKRKPQDGRIKTSFKDKEV- 303
Cdd:TIGR01420   5 ILREAVKLGASDIHL---TAGAPPAMRIDGDLVRI-EFEPLTPEDTQKLAReILS--EKQREEFEENGELDFSFSLPGVg 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 304 ELRVSTLPTAFGEKVVIRIFDPELLlqEVATLGFTPkefeVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTL-STPEV 382
Cdd:TIGR01420  79 RFRVNAFYQRGGVALVLRLIPSKIP--TFEELGLPP----VLRELAERPRGLILVTGPTGSGKSTTLASMIDYInKNKAY 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 383 NIVTIEDPIEMVVEEFNQVGVQSQIGMD---FASSLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDA 459
Cdd:TIGR01420 153 HIITIEDPIEYVHTNKRSLINQREVGEDtlsFANALRAALREDPDVILIGEMRDLETVELALTAAETGHLVFGTLHTNSA 232
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1084827067 460 PTSITRLMDLgIPP-------FLINSTIIGIAAQRLVRK 491
Cdd:TIGR01420 233 AQTIERIIDV-FPAeeqeqirTQLAESLVAIISQRLLPK 270
PilT cd01131
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ...
343-554 4.04e-48

Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.


Pssm-ID: 410875 [Multi-domain]  Cd Length: 223  Bit Score: 167.33  E-value: 4.04e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 343 EVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTL-STPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMD---FASSLRTI 418
Cdd:cd01131    11 PVLKDLALKPRGLVLVTGPTGSGKSTTLAAMIDYInETRSKHIITIEDPIEFVHKHKKSLINQREVGRDtesFAAALRAA 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 419 LRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLgIPP-------FLINSTIIGIAAQRLVRK 491
Cdd:cd01131    91 LREDPDVILVGEMRDLETIELALTAAETGHLVFSTLHTNSAAQTIDRIIDV-FPPeqqeqvrIQLASSLRGVISQRLLPK 169
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1084827067 492 IckscskerlltadeveylrirkdreykvcygegcnecrgtGYRGRVAIYELLEFTDKIRAFV 554
Cdd:cd01131   170 K----------------------------------------DGGGRVAAFEILINTPAIRNLI 192
DotB_TraJ cd19516
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of ...
354-491 7.83e-38

dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of the type IVb secretion (T4bS) system, also known as the dot/icm system, and is the main energy supplier of the secretion system. It is an ATPase, similar to the VirB11 component of the T4aS systems. This family also includes Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ encoded on the tra (transfer) operon.


Pssm-ID: 410924 [Multi-domain]  Cd Length: 179  Bit Score: 137.89  E-value: 7.83e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 354 GIILVTGPTGSGKTTTLYSALKTL---STPEVNIVTIEDPIEMVVEEFNQVG---VQSQIG---MDFASSLRTILRQDPD 424
Cdd:cd19516    12 GLVYVAGATGSGKSTLLAAIYRYIlenDPPDRKIITYEDPIEFVYDGIKSKHsiiVQSQIPrhfKSFAKAVREALRRKPS 91
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1084827067 425 IIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLgIPP-------FLINSTIIGIAAQRLVRK 491
Cdd:cd19516    92 LIGVGELRDQETISAAVEASLTGHPVYSTVHTKSVAETIRRLISL-FPPeerdaaaYDLLSTLRFIIVQRLVRT 164
type_II_IV_secretion_ATPases cd19477
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP ...
354-492 2.85e-37

type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410885 [Multi-domain]  Cd Length: 168  Bit Score: 135.98  E-value: 2.85e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 354 GIILVTGPTGSGKTTTLYSALKTLSTpEVNIVTIEDPIEMVVEEFNQVGvQSQIG--MDFASSLRTILRQDPDIIMVGEI 431
Cdd:cd19477    11 KNVIVCGGTGSGKTTYIKSILEFIPK-EERIISIEDTEEIVFKHHKNYT-QLFFGgnITSADCLKSCLRQRPDRIILGEL 88
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1084827067 432 RDaETANNAVQAALTGH-LVLSTLHTNDAPTSITRLMDLG------------IPPFLINSTIIGIAAQRLVRKI 492
Cdd:cd19477    89 RS-SEAYDFYNVLCSGHkGTLTTLHAGSSEEAFIRLAN*SssnsaarnikfeSLIEGFKDLIDGIVHINHHKQC 161
PilU COG5008
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
354-492 5.53e-32

Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];


Pssm-ID: 444032  Cd Length: 370  Bit Score: 127.14  E-value: 5.53e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 354 GIILVTGPTGSGKTTTLYSALK---TLSTPevNIVTIEDPIEMVVEEFNQVGVQSQIGMD---FASSLRTILRQDPDIIM 427
Cdd:COG5008   124 GLVLFVGATGSGKSTTLAAMIDhrnENSSG--HILTIEDPIEFVHKHKKSIVTQREVGVDtesYEVALKNALRQAPDVIL 201
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1084827067 428 VGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITR-------------LMDLGippflinSTIIGIAAQRLVRKI 492
Cdd:COG5008   202 IGEIRDRETMEHAIAFAETGHLCLATLHANNANQALDRiinffpeerrpqlLMDLS-------LNLRAIVSQRLVPTK 272
plasmid_TraJ TIGR02525
plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated ...
341-490 1.02e-26

plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated with plasmid transfer loci in bacteria. This family is most similar to the DotB ATPase of a type-IV secretion-like system of obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii (TIGR02524). [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 131577 [Multi-domain]  Cd Length: 372  Bit Score: 112.21  E-value: 1.02e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 341 EFEVFNAFLKKTfGIILVTGPTGSGKTTTLYSALKTL--STPEVNIVTIEDPIEMVVEEFNQV--GVQSQIGMD---FAS 413
Cdd:TIGR02525 138 EPDLFNSLLPAA-GLGLICGETGSGKSTLAASIYQHCgeTYPDRKIVTYEDPIEYILGSPDDLlpPAQSQIGRDvdsFAN 216
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 414 SLRTILRQDPDIIMVGEIRDAETANNAVQAALTGHLVLSTLHTNDAPTSITRLMDLgIPP-------FLINSTIIGIAAQ 486
Cdd:TIGR02525 217 GIRLALRRAPKIIGVGEIRDLETFQAAVLAGQSGHFCLGTLHVKSPGEAISRCLQM-YPPemreaaaFDLLSILQYIIVQ 295

                  ....
gi 1084827067 487 RLVR 490
Cdd:TIGR02525 296 RLLR 299
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
356-471 1.13e-21

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 92.60  E-value: 1.13e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTTLySALKTLSTPEVNIVTIEDPIEMVVEEFNQV------GVQSQIGMDFASSLRTILRQDPDIIMVG 429
Cdd:cd01130    15 ILISGGTGSGKTTLL-NALLSFIPPDERIVTIEDTRELQLPHPNVVhlltrpGGGEKGEVTMADLLKAALRMRPDRIIVG 93
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1084827067 430 EIRDAEtANNAVQAALTGHL-VLSTLHTNDAPTSITRLMDLGI 471
Cdd:cd01130    94 EVRGGE-AYDMLQAMNTGHPgSITTIHANSAEDAIDRLATLVL 135
VirB11 COG0630
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ...
356-478 1.53e-19

Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440395 [Multi-domain]  Cd Length: 462  Bit Score: 91.68  E-value: 1.53e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTTLySALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASS-------LRTILRQDPDIIMV 428
Cdd:COG0630   293 VLVAGGTASGKTTLL-NALLSFIPPDAKIVTIEDTRELNLPHENWISLVTRESFGGEEGdvtmfdlLKAALRQRPDYIVV 371
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1084827067 429 GEIRDAEtANNAVQAALTGHLVLSTLHTNDAPTSITRLMD--LGIPPFLINS 478
Cdd:COG0630   372 GEVRGEE-AYTLFQAMATGHGVLSTFHADSVESAINRLTSppINVPRTLLQA 422
T2SSE_N pfam05157
Type II secretion system (T2SS), protein E, N-terminal domain; This domain is found at the ...
82-179 2.64e-19

Type II secretion system (T2SS), protein E, N-terminal domain; This domain is found at the N-terminus of members of the Type II secretion system protein E. Proteins in this subfamily are typically involved in Type 4 pilus biogenesis, though some are involved in other processes; for instance aggregation in Myxococcus xanthus. The structure of this domain is now known.


Pssm-ID: 428339 [Multi-domain]  Cd Length: 108  Bit Score: 83.54  E-value: 2.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  82 LTEDMITEAIAAEVGLPYKKIDPLKINADVaTSFIPRPFAQKHLIVPIEEKDKVVTVALADPYNLDAIEGLQSTGKVKLK 161
Cdd:pfam05157   7 LSEEQLAQALAEQLGLPFVDLEALEIDPEL-LRLLPREFARRHRVLPLREDGGTLVVAVADPLDLALLDELRFLTGKRVE 85
                          90
                  ....*....|....*...
gi 1084827067 162 LVLASKSDILMIIREFYG 179
Cdd:pfam05157  86 PVLATPSDIRRALERLYG 103
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
356-480 1.06e-13

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 72.89  E-value: 1.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTTLySALKTLSTPEVNIVTIEDPIEMVVEEFNQVGVQS---------QIGMdfASSLRTILRQDPDII 426
Cdd:COG4962   185 ILVSGGTGSGKTTLL-NALSGFIPPDERIVTIEDAAELQLQHPHVVRLETrppnvegagEVTL--RDLVRNALRMRPDRI 261
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1084827067 427 MVGEIRDAEtANNAVQAALTGHL-VLSTLHTNDAPTSITRLMDLG------IPPFLINSTI 480
Cdd:COG4962   262 IVGEVRGAE-ALDMLQAMNTGHDgSMSTLHANSARDALARLETLAlmagenLPREAVRRQI 321
PRK13894 PRK13894
conjugal transfer ATPase TrbB; Provisional
356-469 1.73e-12

conjugal transfer ATPase TrbB; Provisional


Pssm-ID: 184377  Cd Length: 319  Bit Score: 68.61  E-value: 1.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTtLYSAL---KTLSTPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIR 432
Cdd:PRK13894  151 ILVIGGTGSGKTT-LVNAIineMVIQDPTERVFIIEDTGEIQCAAENYVQYHTSIDVNMTALLKTTLRMRPDRILVGEVR 229
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1084827067 433 DAEtANNAVQAALTGHL-VLSTLHTNDAPTSITRLMDL 469
Cdd:PRK13894  230 GPE-ALDLLMAWNTGHEgGAATLHANNAKAGLDRLKSL 266
VirB11 TIGR02788
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of ...
356-466 1.88e-12

P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.


Pssm-ID: 274301  Cd Length: 308  Bit Score: 68.53  E-value: 1.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTTLYSALKTLSTPEvNIVTIEDPIEMVVEEFNQV------GVQSQIGMDFASSLRTILRQDPDIIMVG 429
Cdd:TIGR02788 147 IIISGGTGSGKTTFLKSLVDEIPKDE-RIITIEDTREIFLPHPNYVhlfyskGGQGLAKVTPKDLLQSCLRMRPDRIILG 225
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1084827067 430 EIRDAEtANNAVQAALTGHL-VLSTLHTNDAPTSITRL 466
Cdd:TIGR02788 226 ELRGDE-AFDFIRAVNTGHPgSITTLHAGSPEEAFEQL 262
PRK13833 PRK13833
conjugal transfer protein TrbB; Provisional
356-469 8.66e-11

conjugal transfer protein TrbB; Provisional


Pssm-ID: 172360 [Multi-domain]  Cd Length: 323  Bit Score: 63.66  E-value: 8.66e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTTLYSALKTL--STPEVNIVTIEDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDIIMVGEIRD 433
Cdd:PRK13833  147 IVISGGTGSGKTTLANAVIAEIvaSAPEDRLVILEDTAEIQCAAENAVALHTSDTVDMARLLKSTMRLRPDRIIVGEVRD 226
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1084827067 434 AeTANNAVQAALTGHL-VLSTLHTNDAPTSITRLMDL 469
Cdd:PRK13833  227 G-AALTLLKAWNTGHPgGVTTIHSNTAMSALRRLEQL 262
PRK13851 PRK13851
type IV secretion system protein VirB11; Provisional
356-469 3.56e-10

type IV secretion system protein VirB11; Provisional


Pssm-ID: 172375  Cd Length: 344  Bit Score: 61.84  E-value: 3.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTT---TLYSALKtlstPEVNIVTIEDPIEMVVEEFNQVGV---QSQIGMDFASS---LRTILRQDPDII 426
Cdd:PRK13851  165 MLLCGPTGSGKTTmskTLISAIP----PQERLITIEDTLELVIPHENHVRLlysKNGAGLGAVTAehlLQASLRMRPDRI 240
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1084827067 427 MVGEIRDaETANNAVQAALTGHL-VLSTLHTNDAPTSITRLMDL 469
Cdd:PRK13851  241 LLGEMRD-DAAWAYLSEVVSGHPgSISTIHGANPVQGFKKLFSL 283
PRK13900 PRK13900
type IV secretion system ATPase VirB11; Provisional
356-483 2.18e-08

type IV secretion system ATPase VirB11; Provisional


Pssm-ID: 184381  Cd Length: 332  Bit Score: 56.30  E-value: 2.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 356 ILVTGPTGSGKTTTLYSALKTLSTPEvNIVTIEDPIEMVVEEF-NQV------GVQSQIGMDFASSLRTILRQDPDIIMV 428
Cdd:PRK13900  163 IIISGGTSTGKTTFTNAALREIPAIE-RLITVEDAREIVLSNHpNRVhllaskGGQGRAKVTTQDLIEACLRLRPDRIIV 241
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1084827067 429 GEIRDAEtANNAVQAALTGHL-VLSTLHTnDAPTSIT---RLM----DLGIPPFLINSTIIGI 483
Cdd:PRK13900  242 GELRGAE-AFSFLRAINTGHPgSISTLHA-DSPAMAIeqlKLMvmqaGLGMPPDQIKKYILNV 302
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
354-431 1.16e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  354 GIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTI-------EDPIEMVVEEFNQVGVQSQIGMDFASSLRTILRQDPDII 426
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIdgedileEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVL 82

                   ....*
gi 1084827067  427 MVGEI 431
Cdd:smart00382  83 ILDEI 87
nfrB PRK11234
phage adsorption protein NrfB;
60-181 1.52e-03

phage adsorption protein NrfB;


Pssm-ID: 236884 [Multi-domain]  Cd Length: 727  Bit Score: 41.65  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067  60 FISPAEVIAALNFSVPGTT-GRPL------TEDMITEAIAAEVGLPYKKIDPLKINADVAtSFIPRPFAQKHLIVPIEEK 132
Cdd:PRK11234  493 VITEEQLDTALRNRVRGLRlGQSLlmqgliSAEQLAQALAEQNGVAWESLDPWQIPSSLI-AEMPASVALHYAVLPLREE 571
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1084827067 133 DKVVTVA---LADPYNLDAIEGLQstgKVKLKLVLASKSDILMIIREFYGFR 181
Cdd:PRK11234  572 GDELIVAsedGISPVSLAALTRKL---GRKVRYVIVPRGQVTTGLRHWYARR 620
AAA_22 pfam13401
AAA domain;
354-390 4.03e-03

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 37.71  E-value: 4.03e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1084827067 354 GIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDP 390
Cdd:pfam13401   6 GILVLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLP 42
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
343-419 6.83e-03

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 37.51  E-value: 6.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827067 343 EVFNAFLKKTFGIILVTGPTGSGKTTTLYSALKTLSTPEVNIVTIEDP----IEMVVEEFNQVGVQSQIGMDFASSLRTI 418
Cdd:cd00009     9 ALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASdlleGLVVAELFGHFLVRLLFELAEKAKPGVL 88

                  .
gi 1084827067 419 L 419
Cdd:cd00009    89 F 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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