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Conserved domains on  [gi|1084963439|gb|OGR77916|]
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hypothetical protein A2X40_09130 [Elusimicrobia bacterium GWC2_65_9]

Protein Classification

Crp/Fnr family transcriptional regulator( domain architecture ID 11429533)

Crp/Fnr family transcriptional regulator containing a DNA-binding Crp-like helix-turn-helix (HTH) domain, may bind cyclic nucleotides

Gene Ontology:  GO:0003700|GO:0006355|GO:0030552
PubMed:  6280140

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Crp COG0664
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ...
 29-158 3.67e-29

cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms];


:

Pssm-ID: 440428 [Multi-domain]  Cd Length: 207  Bit Score: 106.22  E-value: 3.67e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  29 FKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALLESLPRS 108
Cdd:COG0664     1 FAGLSDEELEALLAHLELRTLKKGEVLFREGDPADHLYFVLSGLVKLYRISEDGREQILGFLGPGDFFGELSLLGGEPSP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1084963439 109 ASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIMSHLARLLSARLRRVTS 158
Cdd:COG0664    81 ATAEALEDSELLRIPREDLEELLERNPELARALLRLLARRLRQLQERLVS 130
 
Name Accession Description Interval E-value
Crp COG0664
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ...
 29-158 3.67e-29

cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms];


Pssm-ID: 440428 [Multi-domain]  Cd Length: 207  Bit Score: 106.22  E-value: 3.67e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  29 FKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALLESLPRS 108
Cdd:COG0664     1 FAGLSDEELEALLAHLELRTLKKGEVLFREGDPADHLYFVLSGLVKLYRISEDGREQILGFLGPGDFFGELSLLGGEPSP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1084963439 109 ASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIMSHLARLLSARLRRVTS 158
Cdd:COG0664    81 ATAEALEDSELLRIPREDLEELLERNPELARALLRLLARRLRQLQERLVS 130
CAP_ED cd00038
effector domain of the CAP family of transcription factors; members include CAP (or cAMP ...
 28-142 6.35e-29

effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels


Pssm-ID: 237999 [Multi-domain]  Cd Length: 115  Bit Score: 102.79  E-value: 6.35e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  28 IFKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALLESLPR 107
Cdd:cd00038     1 LFSGLDDEELEELADALEERRFPAGEVIIRQGDPADSLYIVLSGSVEVYKLDEDGREQIVGFLGPGDLFGELALLGNGPR 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1084963439 108 SASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIM 142
Cdd:cd00038    81 SATVRALTDSELLVLPRSDFRRLLQEYPELARRLL 115
cNMP_binding pfam00027
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ...
 47-132 1.71e-26

Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 459637 [Multi-domain]  Cd Length: 89  Bit Score: 95.75  E-value: 1.71e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  47 RTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALLESLPRSASAAALEPSRVHLLYRSK 126
Cdd:pfam00027   2 RSYKAGEVIFREGDPADSLYIVLSGKVKVYRTLEDGREQILAVLGPGDFFGELALLGGEPRSATVVALTDSELLVIPRED 81


                  ....*.
gi 1084963439 127 LDALLQ 132
Cdd:pfam00027  82 FLELLE 87
cNMP smart00100
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ...
 28-142 2.61e-19

Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases.


Pssm-ID: 197516 [Multi-domain]  Cd Length: 120  Bit Score: 78.60  E-value: 2.61e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439   28 IFKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALL--ESL 105
Cdd:smart00100   1 LFKNLDAEELRELADALEPVRYPAGEVIIRQGDVGDSFYIIVSGEVEVYKVLEDGEEQIVGTLGPGDFFGELALLtnSRR 80

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1084963439  106 PRSASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIM 142
Cdd:smart00100  81 AASAAAVALELATLLRIDFRDFLQLLPELPQLLLELL 117
PRK11753 PRK11753
cAMP-activated global transcriptional regulator CRP;
45-160 7.51e-12

cAMP-activated global transcriptional regulator CRP;


Pssm-ID: 236969 [Multi-domain]  Cd Length: 211  Bit Score: 60.77  E-value: 7.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  45 HSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALL-ESLPRSASAAALEPSRVHLLY 123
Cdd:PRK11753   21 HIHKYPAKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFeEGQERSAWVRAKTACEVAEIS 100

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1084963439 124 RSKLDALLQAEPRIGVTIMSHLARLLSARLRRVtSDL 160
Cdd:PRK11753  101 YKKFRQLIQVNPDILMALSAQMARRLQNTSRKV-GDL 136
cyc_nuc_ocin TIGR03896
bacteriocin-type transport-associated protein; Members of this protein family are ...
 45-153 2.34e-11

bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797.


Pssm-ID: 274839 [Multi-domain]  Cd Length: 317  Bit Score: 60.68  E-value: 2.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  45 HSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIP----LYTLKPGDFFGEMALLESLPRSASAAALEPSRVH 120
Cdd:TIGR03896   9 HQREIAAGTTLIEEGKAADFLFILLDGTFTVTTPQPEDNPLTrafeLARLSRGEIVGEMSLLETRPPVATIKAVPKSRVM 88

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1084963439 121 LLYRSKLDALLQAEprigVTIMSHLARLLSARL 153
Cdd:TIGR03896  89 SIPVGELAAKLQSD----VGFAAHFYRAIAIKL 117
 
Name Accession Description Interval E-value
Crp COG0664
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ...
 29-158 3.67e-29

cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms];


Pssm-ID: 440428 [Multi-domain]  Cd Length: 207  Bit Score: 106.22  E-value: 3.67e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  29 FKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALLESLPRS 108
Cdd:COG0664     1 FAGLSDEELEALLAHLELRTLKKGEVLFREGDPADHLYFVLSGLVKLYRISEDGREQILGFLGPGDFFGELSLLGGEPSP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1084963439 109 ASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIMSHLARLLSARLRRVTS 158
Cdd:COG0664    81 ATAEALEDSELLRIPREDLEELLERNPELARALLRLLARRLRQLQERLVS 130
CAP_ED cd00038
effector domain of the CAP family of transcription factors; members include CAP (or cAMP ...
 28-142 6.35e-29

effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels


Pssm-ID: 237999 [Multi-domain]  Cd Length: 115  Bit Score: 102.79  E-value: 6.35e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  28 IFKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALLESLPR 107
Cdd:cd00038     1 LFSGLDDEELEELADALEERRFPAGEVIIRQGDPADSLYIVLSGSVEVYKLDEDGREQIVGFLGPGDLFGELALLGNGPR 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1084963439 108 SASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIM 142
Cdd:cd00038    81 SATVRALTDSELLVLPRSDFRRLLQEYPELARRLL 115
cNMP_binding pfam00027
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ...
 47-132 1.71e-26

Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 459637 [Multi-domain]  Cd Length: 89  Bit Score: 95.75  E-value: 1.71e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  47 RTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALLESLPRSASAAALEPSRVHLLYRSK 126
Cdd:pfam00027   2 RSYKAGEVIFREGDPADSLYIVLSGKVKVYRTLEDGREQILAVLGPGDFFGELALLGGEPRSATVVALTDSELLVIPRED 81


                  ....*.
gi 1084963439 127 LDALLQ 132
Cdd:pfam00027  82 FLELLE 87
cNMP smart00100
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ...
 28-142 2.61e-19

Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases.


Pssm-ID: 197516 [Multi-domain]  Cd Length: 120  Bit Score: 78.60  E-value: 2.61e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439   28 IFKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALL--ESL 105
Cdd:smart00100   1 LFKNLDAEELRELADALEPVRYPAGEVIIRQGDVGDSFYIIVSGEVEVYKVLEDGEEQIVGTLGPGDFFGELALLtnSRR 80

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1084963439  106 PRSASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIM 142
Cdd:smart00100  81 AASAAAVALELATLLRIDFRDFLQLLPELPQLLLELL 117
PRK11753 PRK11753
cAMP-activated global transcriptional regulator CRP;
45-160 7.51e-12

cAMP-activated global transcriptional regulator CRP;


Pssm-ID: 236969 [Multi-domain]  Cd Length: 211  Bit Score: 60.77  E-value: 7.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  45 HSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMALL-ESLPRSASAAALEPSRVHLLY 123
Cdd:PRK11753   21 HIHKYPAKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFeEGQERSAWVRAKTACEVAEIS 100

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1084963439 124 RSKLDALLQAEPRIGVTIMSHLARLLSARLRRVtSDL 160
Cdd:PRK11753  101 YKKFRQLIQVNPDILMALSAQMARRLQNTSRKV-GDL 136
cyc_nuc_ocin TIGR03896
bacteriocin-type transport-associated protein; Members of this protein family are ...
 45-153 2.34e-11

bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797.


Pssm-ID: 274839 [Multi-domain]  Cd Length: 317  Bit Score: 60.68  E-value: 2.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  45 HSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPIP----LYTLKPGDFFGEMALLESLPRSASAAALEPSRVH 120
Cdd:TIGR03896   9 HQREIAAGTTLIEEGKAADFLFILLDGTFTVTTPQPEDNPLTrafeLARLSRGEIVGEMSLLETRPPVATIKAVPKSRVM 88

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1084963439 121 LLYRSKLDALLQAEprigVTIMSHLARLLSARL 153
Cdd:TIGR03896  89 SIPVGELAAKLQSD----VGFAAHFYRAIAIKL 117
cyc_nuc_ocin TIGR03896
bacteriocin-type transport-associated protein; Members of this protein family are ...
 26-154 2.58e-07

bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797.


Pssm-ID: 274839 [Multi-domain]  Cd Length: 317  Bit Score: 49.12  E-value: 2.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  26 LDIFKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSgPDGKPIPLYTLKPGDFFGEMALLE-S 104
Cdd:TIGR03896 143 LFIFGELHESDVAWMMASGTPQKLPAGTILIHEGGTVDALYILLYGEASLSIS-PDGPGREVGSSRRGEILGETPFLNgS 221

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1084963439 105 LPRSASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIMSHLARLLSARLR 154
Cdd:TIGR03896 222 LPGTATVKAIENSVLLAIDKQQLAAKLQQDVGFASRFYRVIASLLSQRSR 271
PRK13918 PRK13918
CRP/FNR family transcriptional regulator; Provisional
 48-156 1.44e-06

CRP/FNR family transcriptional regulator; Provisional


Pssm-ID: 237557 [Multi-domain]  Cd Length: 202  Bit Score: 46.35  E-value: 1.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  48 TYREGEVIFVEGDIGRA--LFLLESGSVSLARSGPDGKPIPLYTLKPGDFFGEMAlLESLPRSASAAALEPSRVHLLYrs 125
Cdd:PRK13918   10 TYRPGAVILYPGVPGPSdmLYRVRSGLVRLHTVDDEGNALTLRYVRPGEYFGEEA-LAGAERAYFAEAVTDSRIDVLN-- 86

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1084963439 126 klDALLQAEPRIGVTimSHLARLLSARLRRV 156
Cdd:PRK13918   87 --PALMSAEDNLVLT--QHLVRTLARAYESI 113
PLN02868 PLN02868
acyl-CoA thioesterase family protein
 21-97 3.23e-04

acyl-CoA thioesterase family protein


Pssm-ID: 178459 [Multi-domain]  Cd Length: 413  Bit Score: 40.09  E-value: 3.23e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1084963439  21 NFLRSLDIFKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGKPiPLYTLKPGDFFG 97
Cdd:PLN02868    8 EFLGSVPLLQRLPSSSLKKIAEVVVPKRYGKGEYVVREGEPGDGLYFIWKGEAEVSGPAEEESR-PEFLLKRYDYFG 83
ftrB PRK09392
transcriptional activator FtrB; Provisional
 23-147 1.79e-03

transcriptional activator FtrB; Provisional


Pssm-ID: 181817 [Multi-domain]  Cd Length: 236  Bit Score: 37.31  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  23 LRSLDIFKDLKEREFGHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLArSGPDGKPIPLYTLKPGDFFGEMALL 102
Cdd:PRK09392    9 LRNLPLFADMADATFERLMRGAFLQRFPPGTMLITEGEPADFLFVVLDGLVELS-ASSQDRETTLAILRPVSTFILAAVV 87

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1084963439 103 ESLPRSASAAALEPSRVHLLYRSKLDALLQAEPRIGVTIMSHLAR 147
Cdd:PRK09392   88 LDAPYLMSARTLTRSRVLMIPAELVREAMSEDPGFMRAVVFELAG 132
fixK PRK09391
transcriptional regulator FixK; Provisional
 38-161 8.12e-03

transcriptional regulator FixK; Provisional


Pssm-ID: 236494 [Multi-domain]  Cd Length: 230  Bit Score: 35.40  E-value: 8.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084963439  38 GHLVQSLHSRTYREGEVIFVEGDIGRALFLLESGSVSLARSGPDGK-PIPLYTLkPGDFFGemalLESLPR-SASAAALE 115
Cdd:PRK09391   32 GHAGLVASEFSYKKGEEIYGEGEPADYVYQVESGAVRTYRLLSDGRrQIGAFHL-PGDVFG----LESGSThRFTAEAIV 106

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1084963439 116 PSRVHLLYRSKLDALLQAEPrigvtimsHLARLLsarLRRVTSDLR 161
Cdd:PRK09391  107 DTTVRLIKRRSLEQAAATDV--------DVARAL---LSLTAGGLR 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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