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Conserved domains on  [gi|1125076529|gb|OLA39672|]
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hypothetical protein BHW35_00085 [Firmicutes bacterium CAG:176_63_11]

Protein Classification

ATP-binding protein( domain architecture ID 11439316)

ATP-binding protein with an inserted 4Fe-4S ferreoxin, similar to Methanocaldococcus jannaschii proteins, MJ0578 and MJ0579

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 17-76 1.80e-10

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


:

Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 51.27  E-value: 1.80e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125076529 17 KAVQLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG1149    1 VKRKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVVDPDLCTGCGACVGVCPTGAITL 60
 
Name Accession Description Interval E-value
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 17-76 1.80e-10

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 51.27  E-value: 1.80e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125076529 17 KAVQLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG1149    1 VKRKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVVDPDLCTGCGACVGVCPTGAITL 60
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 20-78 9.27e-07

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 43.63  E-value: 9.27e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529  20 QLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLP 78
Cdd:TIGR01944 106 MVALIDEDNCIGCTKCIQACPVDAIVGAAKAMHTVIADECTGCDLCVEPCPTDCIEMIP 164
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
22-78 1.18e-06

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 44.16  E-value: 1.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1125076529  22 AVIDPVRCTGCGWCAMFC---VMKCIDQRPDG--IYEVRQDDCIGCRSCKVNC-FYDAVTMLP 78
Cdd:PRK08318  337 ARIDQDKCIGCGRCYIACedtSHQAIEWDEDGtrTPEVIEEECVGCNLCAHVCpVEGCITMGE 399
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 26-82 1.28e-05

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 40.45  E-value: 1.28e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529  26 PVRCTGCG--WCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLPPRVR 82
Cdd:cd04410    47 PVSCMHCEdpPCVKACPTGAIYKDEDGIVLIDEDKCIGCGSCVEACPYGAIVFDPEPGK 105
Fer4_21 pfam14697
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 22-76 1.18e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 434137 [Multi-domain]  Cd Length: 59  Bit Score: 33.79  E-value: 1.18e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529 22 AVIDPVRCTGCGWCAMFC---VMKCIDQRPDGIYEVRQDDCIGCRSCKVNC-FYDAVTM 76
Cdd:pfam14697  1 ARIDEDTCIGCGKCYIACpdtSHQAIVGDGKRHHTVIEDECTGCNLCVSVCpVDDCITM 59
 
Name Accession Description Interval E-value
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 17-76 1.80e-10

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 51.27  E-value: 1.80e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125076529 17 KAVQLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG1149    1 VKRKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVVDPDLCTGCGACVGVCPTGAITL 60
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 18-78 2.06e-09

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 48.89  E-value: 2.06e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1125076529 18 AVQLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLP 78
Cdd:COG1144   21 RVERPVVDEDKCIGCGLCWIVCPDGAIRVDDGKYYGIDYDYCKGCGICAEVCPVKAIEMVP 81
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 22-79 4.70e-07

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 42.77  E-value: 4.70e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125076529 22 AVIDPVRCTGCGWCAMFCVMKCIDQRPDGI--YEVRQDDCIGCRSCKVNCFYDAVTMLPP 79
Cdd:COG1146    3 PVIDTDKCIGCGACVEVCPVDVLELDEEGKkaLVINPEECIGCGACELVCPVGAITVEDD 62
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 20-78 9.27e-07

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 43.63  E-value: 9.27e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529  20 QLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLP 78
Cdd:TIGR01944 106 MVALIDEDNCIGCTKCIQACPVDAIVGAAKAMHTVIADECTGCDLCVEPCPTDCIEMIP 164
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
22-76 1.01e-06

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 42.03  E-value: 1.01e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1125076529 22 AVIDPVRCTGCGWCAMFCVMKCIDQRpDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG2768    6 PYVDEEKCIGCGACVKVCPVGAISIE-DGKAVIDPEKCIGCGACIEVCPVGAIKI 59
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
22-78 1.18e-06

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 44.16  E-value: 1.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1125076529  22 AVIDPVRCTGCGWCAMFC---VMKCIDQRPDG--IYEVRQDDCIGCRSCKVNC-FYDAVTMLP 78
Cdd:PRK08318  337 ARIDQDKCIGCGRCYIACedtSHQAIEWDEDGtrTPEVIEEECVGCNLCAHVCpVEGCITMGE 399
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 22-76 2.53e-06

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 40.80  E-value: 2.53e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1125076529 22 AVIDPVRCTGCGWCAMFCVMKCIDQRpDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG4231   17 YVIDEDKCTGCGACVKVCPADAIEEG-DGKAVIDPDLCIGCGSCVQVCPVDAIKL 70
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 13-80 4.88e-06

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 40.03  E-value: 4.88e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1125076529 13 PFGRKAVQLAVIDPVRCTGCGWCAMFCVMKCIDQRpDGIYEVRQDDCIGCRSCKVNCFYDAVTMLPPR 80
Cdd:COG2221    1 PYGIIGTWPPKIDEEKCIGCGLCVAVCPTGAISLD-DGKLVIDEEKCIGCGACIRVCPTGAIKGEKPK 67
NapF COG1145
Ferredoxin [Energy production and conversion];
21-78 7.52e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 42.02  E-value: 7.52e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529  21 LAVIDPVRCTGCGWCAMFCVMKCIDQRPDG-IYEVRQDDCIGCRSCKVNCFYDAVTMLP 78
Cdd:COG1145   176 KAVIDAEKCIGCGLCVKVCPTGAIRLKDGKpQIVVDPDKCIGCGACVKVCPVGAISLEP 234
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 26-82 1.28e-05

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 40.45  E-value: 1.28e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529  26 PVRCTGCG--WCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLPPRVR 82
Cdd:cd04410    47 PVSCMHCEdpPCVKACPTGAIYKDEDGIVLIDEDKCIGCGSCVEACPYGAIVFDPEPGK 105
PRK06991 PRK06991
electron transport complex subunit RsxB;
9-78 2.83e-05

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 40.16  E-value: 2.83e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125076529   9 DPAHPFGRkAVQLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLP 78
Cdd:PRK06991   68 DPANGVER-PRAVAVIDEQLCIGCTLCMQACPVDAIVGAPKQMHTVLADLCTGCDLCVPPCPVDCIDMVP 136
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
18-76 3.17e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 40.23  E-value: 3.17e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529  18 AVQLAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG1148   487 EPSVAEVDPEKCTGCGRCVEVCPYGAISIDEKGVAEVNPALCKGCGTCAAACPSGAISL 545
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 26-80 3.54e-05

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 39.54  E-value: 3.54e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1125076529  26 PVRCTGCG--WCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLPPR 80
Cdd:COG0437    57 PVLCNHCDdpPCVKVCPTGATYKREDGIVLVDYDKCIGCRYCVAACPYGAPRFNPET 113
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 35-78 4.21e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 39.08  E-value: 4.21e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1125076529  35 CAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLP 78
Cdd:cd16371    62 CVKVCPTGAITKREDGIVVVDQDKCIGCGYCVWACPYGAPQYNP 105
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 23-76 5.98e-05

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 38.53  E-value: 5.98e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1125076529  23 VIDPVRCTGCGWCAMFCVMKCIDQRPDGI--------YEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:cd10549    36 EIDEDKCVFCGACVEVCPTGAIELTPEGKeyvpkekeAEIDEEKCIGCGLCVKVCPVDAITL 97
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
21-76 7.09e-05

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 38.00  E-value: 7.09e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1125076529  21 LAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:PRK09623   45 MPVVDESKCVKCYICWKFCPEPAIYIKEDGYVAIDYDYCKGCGICANECPTKAITM 100
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 21-81 1.87e-04

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 37.75  E-value: 1.87e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1125076529  21 LAVIDPVRCTGCGWCAMFCVMKCIDQRPDGIyEVRQDDCIGCRSCKVNCFYDAVTmLPPRV 81
Cdd:cd03110    58 KAFIDQEKCIRCGNCERVCKFGAILEFFQKL-IVDESLCEGCGACVIICPRGAIY-LKDRD 116
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
24-76 3.22e-04

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 36.96  E-value: 3.22e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1125076529  24 IDPVRCTGCGWCAMFCVMKCIDQRPdgiyEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG0348   207 YDRGDCIDCGLCVKVCPMGIDIRKG----EINQSECINCGRCIDACPKDAIRF 255
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 46-78 3.60e-04

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 36.74  E-value: 3.60e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1125076529  46 QRPDGIYEVRQDDCIGCRSCKVNCFYDAVTMLP 78
Cdd:cd10551    72 KREDGIVLVDYDKCIGCRYCMAACPYGARYFNP 104
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
22-69 6.27e-04

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 36.54  E-value: 6.27e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1125076529  22 AVIDPVRCTGCGWCAMFCVMKCIDQRpDGIYEVRQDDCIGCRSCKVNC 69
Cdd:COG4624    86 IIRDKEKCKNCYPCVRACPVKAIKVD-DGKAEIDEEKCISCGQCVAVC 132
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 22-76 7.18e-04

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 35.45  E-value: 7.18e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1125076529  22 AVIDPVRCTGCGWCAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:cd10549    73 AEIDEEKCIGCGLCVKVCPVDAITLEDELEIVIDKEKCIGCGICAEVCPVNAIKL 127
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 26-76 9.09e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 35.88  E-value: 9.09e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1125076529  26 PVRCTGC--GWCAMFCVMKCIDQRPDGIyEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:PRK12769   53 AVTCHHCedAPCARSCPNGAISHVDDSI-QVNQQKCIGCKSCVVACPFGTMQI 104
Fer4_21 pfam14697
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 22-76 1.18e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 434137 [Multi-domain]  Cd Length: 59  Bit Score: 33.79  E-value: 1.18e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125076529 22 AVIDPVRCTGCGWCAMFC---VMKCIDQRPDGIYEVRQDDCIGCRSCKVNC-FYDAVTM 76
Cdd:pfam14697  1 ARIDEDTCIGCGKCYIACpdtSHQAIVGDGKRHHTVIEDECTGCNLCVSVCpVDDCITM 59
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 35-74 1.50e-03

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 35.07  E-value: 1.50e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1125076529  35 CAMFCVMKCIDQRPDGIYEVRQDDCIGCRSCKVNCFYDAV 74
Cdd:cd16366    78 CLAACPTGAIIRTETGTVVVDPETCIGCGYCVNACPFDIP 117
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 28-81 1.61e-03

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 33.57  E-value: 1.61e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1125076529 28 RCTGCGWCAMFCVMKCIDQRPDG---IYEVRQDDCIGCRSCKVNCFYDAVTMLPPRV 81
Cdd:COG1143    3 KCIGCGLCVRVCPVDAITIEDGEpgkVYVIDPDKCIGCGLCVEVCPTGAISMTPFEL 59
PRK13795 PRK13795
hypothetical protein; Provisional
 17-65 2.59e-03

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 34.58  E-value: 2.59e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1125076529  17 KAVQLAVIDPVRCTGCGWCAMFCVMKCID-QRPDGIYEVRQDDCIGCRSC 65
Cdd:PRK13795  571 KDAARLLRRAAECVGCGVCVGACPTGAIRiEEGKRKISVDEEKCIHCGKC 620
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
21-76 2.94e-03

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 34.52  E-value: 2.94e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1125076529  21 LAVIDPVRCTGCGWCAMFCVMKCIDQRPDG----IYEVRQDD-----------CIGCRSCKVNCFYDAVTM 76
Cdd:PRK07118  162 LPVVDEDKCTGCGACVKACPRNVIELIPKSarvfVACNSKDKgkavkkvcevgCIGCGKCVKACPAGAITM 232
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
13-47 3.17e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 34.45  E-value: 3.17e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1125076529  13 PFG---RKAVQLAVIDPVRCTGCGWCAMFCVMKCIDQR 47
Cdd:COG1148   509 PYGaisIDEKGVAEVNPALCKGCGTCAAACPSGAISLK 546
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
23-76 9.95e-03

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 32.71  E-value: 9.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1125076529  23 VIDPVRCTGC--GWCAMFCVMKCIdQRPDGIYEVRQDDCIGCRSCKVNCFYDAVTM 76
Cdd:COG1142    46 VSAPVQCRHCedAPCAEVCPVGAI-TRDDGAVVVDEEKCIGCGLCVLACPFGAITM 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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