NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1125172690|gb|OLB27560|]
View 

hypothetical protein AUH95_00090 [Nitrospirae bacterium 13_2_20CM_2_63_8]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 13-152 6.69e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 6.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  13 IRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEFQAQLAE 92
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1125172690  93 LP----QLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKA 152
Cdd:COG1196   314 LEerleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 13-152 6.69e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 6.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  13 IRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEFQAQLAE 92
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1125172690  93 LP----QLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKA 152
Cdd:COG1196   314 LEerleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 7-147 1.45e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    7 RQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDA-------KQTELMTARAERDQL 79
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAlaneisrLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1125172690   80 VQAKAEFQAQLAELPQLRQTAVEAKAA----ETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSR 147
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAEleekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
7-144 4.39e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.64  E-value: 4.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   7 RQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEF 86
Cdd:PRK02224  352 DDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAEL 431

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1125172690  87 QAQLAELPQLRQTAVEAKAA-----------ETSVQARMKELESSMATLTTELEQVKKTLARLQNESDT 144
Cdd:PRK02224  432 EATLRTARERVEEAEALLEAgkcpecgqpveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER 500
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 8-133 4.65e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 36.15  E-value: 4.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    8 QLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQqafDAKQTELMTARAErdqLVQAKAEFQ 87
Cdd:smart00787 148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELE---DCDPTELDRAKEK---LKKLLQEIM 221

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1125172690   88 AQLAELPQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKK 133
Cdd:smart00787 222 IKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRG 267
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 13-152 6.69e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 6.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  13 IRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEFQAQLAE 92
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1125172690  93 LP----QLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKA 152
Cdd:COG1196   314 LEerleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-154 1.09e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   4 AAQRQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAK 83
Cdd:COG1196   316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1125172690  84 AEFQAQLAELPQLRQTAVEAKA----AETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKAGK 154
Cdd:COG1196   396 AELAAQLEELEEAEEALLERLErleeELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 7-152 1.47e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   7 RQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEF 86
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  87 QAQLAEL----PQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKA 152
Cdd:COG1196   315 EERLEELeeelAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-141 1.06e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   4 AAQRQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAK 83
Cdd:COG1196   260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1125172690  84 AEFQAQLAElpqLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNE 141
Cdd:COG1196   340 EELEEELEE---AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
4-141 4.15e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    4 AAQRQLETVIRDMRAEAAAIRNEMAATRIAAAKKE--------AELQELRHQVAELRQARAEQQQAFDAKQTELMTARAE 75
Cdd:COG4913    642 ALQERREALQRLAEYSWDEIDVASAEREIAELEAElerldassDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE 721

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1125172690   76 RDQLVQAKAEFQAQLAELPQLRQTAVEAKAAETSVQARMKELESSM-ATLTTELEQVKKTLARLQNE 141
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELrENLEERIDALRARLNRAEEE 788
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
5-152 6.23e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 6.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    5 AQRQLETVIRDMRAEAAAIRNemAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKA 84
Cdd:COG4913    608 NRAKLAALEAELAELEEELAE--AEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSD 685

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1125172690   85 EFQAQLAELPQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKA 152
Cdd:COG4913    686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE 753
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1-141 9.45e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 9.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    1 MAPAAQRQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQ-QAFDAKQTELMTARAERDQL 79
Cdd:COG4913    278 RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEER 357

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   80 VQAKAEFQAQLAEL--------PQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNE 141
Cdd:COG4913    358 ERRRARLEALLAALglplpasaEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-152 1.15e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   4 AAQRQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAK 83
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1125172690  84 AEFQAQLAElpqLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKA 152
Cdd:COG1196   368 LEAEAELAE---AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 3-103 1.40e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 40.84  E-value: 1.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   3 PAAQRQLETVIRDMRAE-AAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQT---ELMTARAERDQ 78
Cdd:COG0542   410 PEELDELERRLEQLEIEkEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQElkeELEQRYGKIPE 489

                          90       100
                  ....*....|....*....|....*
gi 1125172690  79 LVQAKAEFQAQLAELPQLRQTAVEA 103
Cdd:COG0542   490 LEKELAELEEELAELAPLLREEVTE 514
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 7-147 1.45e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    7 RQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDA-------KQTELMTARAERDQL 79
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAlaneisrLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1125172690   80 VQAKAEFQAQLAELPQLRQTAVEAKAA----ETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSR 147
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAEleekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 17-152 1.53e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 1.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   17 RAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELmtaRAERDQLVQAKAEFQAQLAELPQL 96
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI---SALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1125172690   97 RQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSRTSAKA 152
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 7-141 2.46e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 2.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    7 RQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEF 86
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1125172690   87 QAQLAELpQLRQTAVEAKAAETSVQAR------MKELESSMATLTTELEQVKKTLARLQNE 141
Cdd:TIGR02168  921 REKLAQL-ELRLEGLEVRIDNLQERLSeeysltLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 15-147 3.39e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 3.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   15 DMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAE----RDQLVQAKAEFQAQL 90
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEierlEARLERLEDRRERLQ 420

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1125172690   91 AELPQLRQTAVEAKAAEtsVQARMKELESSMATLTTELEQVKKTLARLQNESDTKSR 147
Cdd:TIGR02168  421 QEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
7-144 4.39e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.64  E-value: 4.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   7 RQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEF 86
Cdd:PRK02224  352 DDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAEL 431

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1125172690  87 QAQLAELPQLRQTAVEAKAA-----------ETSVQARMKELESSMATLTTELEQVKKTLARLQNESDT 144
Cdd:PRK02224  432 EATLRTARERVEEAEALLEAgkcpecgqpveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER 500
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 13-145 5.18e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 5.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   13 IRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEFQAQLAe 92
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA- 312

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1125172690   93 lpQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESDTK 145
Cdd:TIGR02168  313 --NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL 363
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 8-143 5.53e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 5.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    8 QLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEFQ 87
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   88 AQLAEL----PQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESD 143
Cdd:TIGR02168  859 AEIEELeeliEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE 918
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
16-144 6.90e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 38.87  E-value: 6.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  16 MRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDA--KQTELMTARAERDQLVQAKAEFQAQLAEL 93
Cdd:PRK02224  542 LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESleRIRTLLAAIADAEDEIERLREKREALAEL 621

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1125172690  94 PQLRQTAVEAKA------AETSVQARMKELESSMATLTTELEQVKKTLARLQNESDT 144
Cdd:PRK02224  622 NDERRERLAEKRerkrelEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDD 678
PRK09039 PRK09039
peptidoglycan -binding protein;
35-140 1.43e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 37.64  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  35 AKKEAELQELRHQVAEL-------RQARAEQQQAFDAKQTELMTARAERDQLVQAKAEFQAQLAELPQLRQTAVEAKAAE 107
Cdd:PRK09039   49 SGKDSALDRLNSQIAELadllsleRQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSE 128

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1125172690 108 TSVQARMKeleSSMATLTTELEQVKKTLARLQN 140
Cdd:PRK09039  129 KQVSARAL---AQVELLNQQIAALRRQLAALEA 158
PRK10920 PRK10920
putative uroporphyrinogen III C-methyltransferase; Provisional
 34-93 1.84e-03

putative uroporphyrinogen III C-methyltransferase; Provisional


Pssm-ID: 236795  Cd Length: 390  Bit Score: 37.38  E-value: 1.84e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1125172690  34 AAKKEAELQELRHQVAELRQARAEQQQAFDAKQTE----LMTARAERDQLVQAKAEFQAQLAEL 93
Cdd:PRK10920   62 AQNQTATNDALANQLTALQKAQESQKQELEGILKQqakaLDQANRQQAALAKQLDELQQKVATI 125
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 36-141 4.60e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 36.45  E-value: 4.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  36 KKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAKAEFQAQLAELPQLRQTAVEAKAAETSVQARMK 115
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                          90       100
                  ....*....|....*....|....*.
gi 1125172690 116 ELESSMATLTTELEQVKKTLARLQNE 141
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEE 324
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 8-133 4.65e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 36.15  E-value: 4.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    8 QLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQqafDAKQTELMTARAErdqLVQAKAEFQ 87
Cdd:smart00787 148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELE---DCDPTELDRAKEK---LKKLLQEIM 221

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1125172690   88 AQLAELPQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKK 133
Cdd:smart00787 222 IKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRG 267
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 4-144 5.43e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 36.19  E-value: 5.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    4 AAQRQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQLVQAK 83
Cdd:TIGR02168  803 EALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1125172690   84 AEFQAQLAELpQLRQTAVEAKAAETSvqARMKELESSMATLTTELEQVKKTLARLQNESDT 144
Cdd:TIGR02168  883 ASLEEALALL-RSELEELSEELRELE--SKRSELRRELEELREKLAQLELRLEGLEVRIDN 940
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 38-141 6.34e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 35.97  E-value: 6.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690  38 EAELQELRHQVAELRQARAEQQQAFDA---KQTELM-TARAERDQLVQAKAEFQAQLAELPQLRQTAVEAKAAETSVQAR 113
Cdd:PRK04778  118 EEDIEQILEELQELLESEEKNREEVEQlkdLYRELRkSLLANRFSFGPALDELEKQLENLEEEFSQFVELTESGDYVEAR 197

                          90       100       110
                  ....*....|....*....|....*....|
gi 1125172690 114 M--KELESSMATLTTELEQVKKTLARLQNE 141
Cdd:PRK04778  198 EilDQLEEELAALEQIMEEIPELLKELQTE 227
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
13-143 6.60e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 36.05  E-value: 6.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   13 IRDMRAEAAAIRNEMAATRIAAAKK-----EAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQL-VQAKAEF 86
Cdd:COG4913    264 YAAARERLAELEYLRAALRLWFAQRrlellEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQL 343

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1125172690   87 QAQLAelpQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNESD 143
Cdd:COG4913    344 EREIE---RLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALE 397
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
9-135 6.86e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 35.99  E-value: 6.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   9 LETVIRDMRAEAAAIRNEMAATRIAAA------------KKEAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAER 76
Cdd:COG2433   378 IEEALEELIEKELPEEEPEAEREKEHEerelteeeeeirRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEE 457

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1125172690  77 DQLVQAKAEFQAQLAELPQLRqtaveakaaetsvqARMKELESSMATLTTELEQVKKTL 135
Cdd:COG2433   458 RREIRKDREISRLDREIERLE--------------RELEEERERIEELKRKLERLKELW 502
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 38-121 7.08e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 36.08  E-value: 7.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   38 EAELQELRHQVAELRQARAEQQQAFDAKQTELMTARAERDQL----VQAKAEFQAQLAELPQLRQtaveaKAAETSVQAR 113
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALeglaAELEEKQQELEAQLEQLQE-----KAAETSQERK 215


                   ....*...
gi 1125172690  114 MKELESSM 121
Cdd:PRK11448   216 QKRKEITD 223
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 7-141 7.55e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 36.07  E-value: 7.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690   7 RQLETVIRDMRAEAAAIRNEMAATRIAAAKKEAEL--QELRHQVAELRQARAEQQQAfdakqteLMTARAERDQLVQAKA 84
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEEleAELEELEAELAELEAELEEL-------RLELEELELELEEAQA 288

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1125172690  85 EFQAQLAELPQLRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLARLQNE 141
Cdd:COG1196   289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
4-137 8.26e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 35.66  E-value: 8.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125172690    4 AAQRQLETVIRDMRA----EAAAIRNEMAATRIAAAKKEAELQELRHQVAELRQARAEQQQAFDAKQTElmtARAERDQL 79
Cdd:COG4913    320 ALREELDELEAQIRGnggdRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE---AAALLEAL 396

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1125172690   80 VQAKAEFQAQLAELpqlRQTAVEAKAAETSVQARMKELESSMATLTTELEQVKKTLAR 137
Cdd:COG4913    397 EEELEALEEALAEA---EAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAE 451
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH