|
Name |
Accession |
Description |
Interval |
E-value |
| PFKA_PPi_Ttgales |
NF041103 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
4-378 |
0e+00 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 469029 Cd Length: 406 Bit Score: 595.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDTEHVVELTINDLSRIHFDGGSIIRTSRTNPARTPE 83
Cdd:NF041103 1 LAILVGGGPAPGINSVISAVTIEAINHGWEVLGIYDGFKHLAKGDTSKVIPLTIDDVSRIHFRGGSILGTSRANPTKSEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 84 GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPG-LGLAHVPKTIDNDLPLPSDIDTFGFSTACNLGKDLVRNLMQ 162
Cdd:NF041103 81 DLENVVDTLKELGVTHLVTIGGDDTAFSASKVAKYAGGrIRVVHVPKTIDNDLPLPEGIPTFGFETARHVGVELVKNLME 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 163 DAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAILSEGLAEK 242
Cdd:NF041103 161 DARTTNRWYFVVAMGRKAGHLALGIGKAAGATLTIIPEEFREEKITLQTVVDILVGSIIKRLAMGRNYGVAVLAEGLIEK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 243 L---DLESLGPVERDQYGNVRLAELDLGRVLKDRVAGRLRERKVDVTIVGKDLGYELRCAAPGAHDIQYSRSLGYWATRF 319
Cdd:NF041103 241 IdpeDLEALGGVERDEHGHIRLAEINFGEILKKAVKKRLKELGIKITIVDKNIGYELRCADPIPFDIEYTRDLGYGAVRF 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1125209119 320 LLEGGSNAMVTIQAGRLVPMPFGLLLDPKTGKIRVRYVDVESEMYQTLWAYMIRLKPED 378
Cdd:NF041103 321 LLEGGTGAMISIQNGRFVPIPFEDMLDPKTGRTRVRMVDVESESYRIARRYMIRLEKED 379
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-366 |
1.74e-99 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 298.53 E-value: 1.74e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 1 MRTLAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPAR 80
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGD---IIDLTREDVSGILQRGGTILGSSRSKPFK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 81 TPEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALpGLGLAHVPKTIDNDLPLpsdID-TFGFSTACNLGKDLVRN 159
Cdd:COG0205 78 TEEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEY-GIPVVGIPKTIDNDLPG---TDyTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 160 LMQDAATTERWFFVTVMGRRAGHlalgiggaagatLTVV------AEEFL--ESKITVDRLADilegAIIKRRMHGRDHG 231
Cdd:COG0205 154 LRDTAASHERVFVVEVMGRHAGW------------LALAaglaggADLILipEVPFDLDKLLE----KLKERRKRGKGYS 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 232 VAILSEGLAEKlDLESLGPVERDQYGNVRLAelDLGRVLKDRVAGRLrERKVDVTIvgkdLGYELRCAAPGAHDIQYSRS 311
Cdd:COG0205 218 IIVVAEGAGDE-DGEAVLEADTDAFGHVRLG--GIGEYLAKEIEERT-GIETRVTV----LGHLQRGGSPSAFDRVLASR 289
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1125209119 312 LGYWATRFLLEGGSNAMVTIQAGRLVPMPFGLLLDpktgkiRVRYVDVESEMYQT 366
Cdd:COG0205 290 LGAAAVELLLEGKTGVMVGIRRGEIVLVPLEEVAN------KEKPVDPDSPLIQL 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-238 |
3.39e-58 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 190.24 E-value: 3.39e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDTEhvvELTINDLSRIHFDGGSIIRTSRTNPARTPE 83
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDID---ELTWRDVSGILNRGGTILGTSRSKPFKTEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 84 GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALpGLGLAHVPKTIDNDLPLpSDIdTFGFSTACNLGKDLVRNLMQD 163
Cdd:pfam00365 79 GREKIAENLKKLGIDALVVIGGDGSLTGANKLSEER-GIPVVGIPKTIDNDIPG-TDY-TIGFDTALNTIVEAIDRIRDT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 164 AATTERWFFVTVMGRRAGHlalgiggaagatLTVV------AEEFL--ESKITVDRLADilegaIIKRRMHGRDHGVAIL 235
Cdd:pfam00365 156 ASSHNRVFVVEVMGRHCGW------------LALMaglaggADAILipEIPFDIEELCE-----KIKELRKGKRFSIIVV 218
|
...
gi 1125209119 236 SEG 238
Cdd:pfam00365 219 AEG 221
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-363 |
9.97e-55 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 182.59 E-value: 9.97e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 1 MRTLAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDTehvVELTINDLSRIHFDGGSIIRTSRTNPAR 80
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDI---VKLDLKSVSDIINRGGTILGSARFPEFK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 81 TPEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKAlpGLGLAHVPKTIDNDLPLpSDIdTFGFSTACNLGKDLVRNL 160
Cdd:PRK03202 78 DEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEH--GIPVIGLPGTIDNDIAG-TDY-TIGFDTALNTAVEAIDRL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 161 MQDAATTERWFFVTVMGRRAGHlalgiggaagatLTVV------AEEFL--ESKITVDRLADILEgaiiKRRMHGRDHGV 232
Cdd:PRK03202 154 RDTASSHERVFIVEVMGRHAGD------------LALHagiaggAEVILipEVPFDIEELCAKIK----KGRERGKKHAI 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 233 AILSEGlaekldlesLGPVErdqygnvrlaelDLGRVLKDRVAGRLRerkvdVTIvgkdLGYELRCAAPGAHD-IQYSRs 311
Cdd:PRK03202 218 IVVAEG---------VMPAE------------ELAKEIEERTGLETR-----VTV----LGHIQRGGSPTAFDrVLASR- 266
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1125209119 312 LGYWATRFLLEGGSNAMVTIQAGRLVPMPFGLLLDPKTGKIRVRYVDVESEM 363
Cdd:PRK03202 267 MGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKL 318
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
5-334 |
1.41e-52 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 177.88 E-value: 1.41e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 5 AILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPARTPEG 84
Cdd:cd00363 4 GVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGD---IKELDWESVSDIINRGGTIIGSARCKEFRTEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 85 VGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGL----AHVPKTIDNDLPlPSDIdTFGFSTACNLGKDLVRNL 160
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQgfnvIGLPGTIDNDIK-GTDY-TIGFDTALKTIVEAIDRI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 161 MQDAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKItVDRLADILEgaiiKRRMHGRDHGVAILSEGLA 240
Cdd:cd00363 159 RDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEW-EEEMVDVIK----KRRERGKRHGIVIVAEGAI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 241 EKLdleslgpverdqygNVRLAELDLGRVLKDRVAGRLRerkvdVTIvgkdLGYELRCAAPGAHDIQYSRSLGYWATRFL 320
Cdd:cd00363 234 DFI--------------PKPITEKLLAKLVEERLGFDTR-----ATV----LGHVQRGGTPTAFDRILASRLGAEAVELL 290
|
330
....*....|....
gi 1125209119 321 LEGGSNAMVTIQAG 334
Cdd:cd00363 291 LEGTGGTPVGIQNL 304
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
4-341 |
2.53e-44 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 155.54 E-value: 2.53e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEA-RNHGVRVLGCYDGFKWLVEGDTehVVELTINDLSRIHFDGGSIIRTSRTNPARTP 82
Cdd:TIGR02483 2 IGVLTGGGDCPGLNAVIRGVVRRAiAEYGWEVIGIRDGWRGLLEGDT--VPLLDLEDVRGILPRGGTILGSSRTNPFKYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 83 E-GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKAlpGLGLAHVPKTIDNDLpLPSDIdTFGFSTACNLGKDLVRNLM 161
Cdd:TIGR02483 80 EdGDDKIVANLKELGLDALIAIGGDGTLGIARRLADK--GLPVVGVPKTIDNDL-EATDY-TFGFDTAVEIATEALDRLH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 162 QDAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEflesKITVDRLADilegAIIKRRMHGRDHGVAILSEGLAE 241
Cdd:TIGR02483 156 TTAESHHRVMVVEVMGRHAGWIALHSGIAGGADVILIPEI----PFDIDSVCE----KVRERFARGKRFAIVVVAEGAKP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 242 KLDLESLGPVERDQYGNVRLAelDLGRVLKDRVAGRLrERKVDVTIvgkdLGYELRCAAPGAHDIQYSRSLGYWATRFLL 321
Cdd:TIGR02483 228 KGGEMVVQEGVKDAFGHVRLG--GIGNWLAEEIERRT-GIETRATV----LGHLQRGGSPSAFDRVLATRFGVAAVDLVH 300
|
330 340
....*....|....*....|
gi 1125209119 322 EGGSNAMVTIQAGRLVPMPF 341
Cdd:TIGR02483 301 EGQFGHMVALRGTDIVYVPI 320
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PFKA_PPi_Ttgales |
NF041103 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
4-378 |
0e+00 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 469029 Cd Length: 406 Bit Score: 595.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDTEHVVELTINDLSRIHFDGGSIIRTSRTNPARTPE 83
Cdd:NF041103 1 LAILVGGGPAPGINSVISAVTIEAINHGWEVLGIYDGFKHLAKGDTSKVIPLTIDDVSRIHFRGGSILGTSRANPTKSEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 84 GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPG-LGLAHVPKTIDNDLPLPSDIDTFGFSTACNLGKDLVRNLMQ 162
Cdd:NF041103 81 DLENVVDTLKELGVTHLVTIGGDDTAFSASKVAKYAGGrIRVVHVPKTIDNDLPLPEGIPTFGFETARHVGVELVKNLME 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 163 DAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAILSEGLAEK 242
Cdd:NF041103 161 DARTTNRWYFVVAMGRKAGHLALGIGKAAGATLTIIPEEFREEKITLQTVVDILVGSIIKRLAMGRNYGVAVLAEGLIEK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 243 L---DLESLGPVERDQYGNVRLAELDLGRVLKDRVAGRLRERKVDVTIVGKDLGYELRCAAPGAHDIQYSRSLGYWATRF 319
Cdd:NF041103 241 IdpeDLEALGGVERDEHGHIRLAEINFGEILKKAVKKRLKELGIKITIVDKNIGYELRCADPIPFDIEYTRDLGYGAVRF 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1125209119 320 LLEGGSNAMVTIQAGRLVPMPFGLLLDPKTGKIRVRYVDVESEMYQTLWAYMIRLKPED 378
Cdd:NF041103 321 LLEGGTGAMISIQNGRFVPIPFEDMLDPKTGRTRVRMVDVESESYRIARRYMIRLEKED 379
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-366 |
1.74e-99 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 298.53 E-value: 1.74e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 1 MRTLAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPAR 80
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGD---IIDLTREDVSGILQRGGTILGSSRSKPFK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 81 TPEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALpGLGLAHVPKTIDNDLPLpsdID-TFGFSTACNLGKDLVRN 159
Cdd:COG0205 78 TEEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEY-GIPVVGIPKTIDNDLPG---TDyTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 160 LMQDAATTERWFFVTVMGRRAGHlalgiggaagatLTVV------AEEFL--ESKITVDRLADilegAIIKRRMHGRDHG 231
Cdd:COG0205 154 LRDTAASHERVFVVEVMGRHAGW------------LALAaglaggADLILipEVPFDLDKLLE----KLKERRKRGKGYS 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 232 VAILSEGLAEKlDLESLGPVERDQYGNVRLAelDLGRVLKDRVAGRLrERKVDVTIvgkdLGYELRCAAPGAHDIQYSRS 311
Cdd:COG0205 218 IIVVAEGAGDE-DGEAVLEADTDAFGHVRLG--GIGEYLAKEIEERT-GIETRVTV----LGHLQRGGSPSAFDRVLASR 289
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1125209119 312 LGYWATRFLLEGGSNAMVTIQAGRLVPMPFGLLLDpktgkiRVRYVDVESEMYQT 366
Cdd:COG0205 290 LGAAAVELLLEGKTGVMVGIRRGEIVLVPLEEVAN------KEKPVDPDSPLIQL 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-238 |
3.39e-58 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 190.24 E-value: 3.39e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDTEhvvELTINDLSRIHFDGGSIIRTSRTNPARTPE 83
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDID---ELTWRDVSGILNRGGTILGTSRSKPFKTEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 84 GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALpGLGLAHVPKTIDNDLPLpSDIdTFGFSTACNLGKDLVRNLMQD 163
Cdd:pfam00365 79 GREKIAENLKKLGIDALVVIGGDGSLTGANKLSEER-GIPVVGIPKTIDNDIPG-TDY-TIGFDTALNTIVEAIDRIRDT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 164 AATTERWFFVTVMGRRAGHlalgiggaagatLTVV------AEEFL--ESKITVDRLADilegaIIKRRMHGRDHGVAIL 235
Cdd:pfam00365 156 ASSHNRVFVVEVMGRHCGW------------LALMaglaggADAILipEIPFDIEELCE-----KIKELRKGKRFSIIVV 218
|
...
gi 1125209119 236 SEG 238
Cdd:pfam00365 219 AEG 221
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-363 |
9.97e-55 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 182.59 E-value: 9.97e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 1 MRTLAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDTehvVELTINDLSRIHFDGGSIIRTSRTNPAR 80
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDI---VKLDLKSVSDIINRGGTILGSARFPEFK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 81 TPEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKAlpGLGLAHVPKTIDNDLPLpSDIdTFGFSTACNLGKDLVRNL 160
Cdd:PRK03202 78 DEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEH--GIPVIGLPGTIDNDIAG-TDY-TIGFDTALNTAVEAIDRL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 161 MQDAATTERWFFVTVMGRRAGHlalgiggaagatLTVV------AEEFL--ESKITVDRLADILEgaiiKRRMHGRDHGV 232
Cdd:PRK03202 154 RDTASSHERVFIVEVMGRHAGD------------LALHagiaggAEVILipEVPFDIEELCAKIK----KGRERGKKHAI 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 233 AILSEGlaekldlesLGPVErdqygnvrlaelDLGRVLKDRVAGRLRerkvdVTIvgkdLGYELRCAAPGAHD-IQYSRs 311
Cdd:PRK03202 218 IVVAEG---------VMPAE------------ELAKEIEERTGLETR-----VTV----LGHIQRGGSPTAFDrVLASR- 266
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1125209119 312 LGYWATRFLLEGGSNAMVTIQAGRLVPMPFGLLLDPKTGKIRVRYVDVESEM 363
Cdd:PRK03202 267 MGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKL 318
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
5-334 |
1.41e-52 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 177.88 E-value: 1.41e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 5 AILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPARTPEG 84
Cdd:cd00363 4 GVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGD---IKELDWESVSDIINRGGTIIGSARCKEFRTEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 85 VGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGL----AHVPKTIDNDLPlPSDIdTFGFSTACNLGKDLVRNL 160
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQgfnvIGLPGTIDNDIK-GTDY-TIGFDTALKTIVEAIDRI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 161 MQDAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKItVDRLADILEgaiiKRRMHGRDHGVAILSEGLA 240
Cdd:cd00363 159 RDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEW-EEEMVDVIK----KRRERGKRHGIVIVAEGAI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 241 EKLdleslgpverdqygNVRLAELDLGRVLKDRVAGRLRerkvdVTIvgkdLGYELRCAAPGAHDIQYSRSLGYWATRFL 320
Cdd:cd00363 234 DFI--------------PKPITEKLLAKLVEERLGFDTR-----ATV----LGHVQRGGTPTAFDRILASRLGAEAVELL 290
|
330
....*....|....
gi 1125209119 321 LEGGSNAMVTIQAG 334
Cdd:cd00363 291 LEGTGGTPVGIQNL 304
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
5-370 |
1.33e-45 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 164.32 E-value: 1.33e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 5 AILVGGGPAPGINAVIAA--ATIEARNHGVRVLGCYDGFKWLVEGDTehvVELTINDLSRIHFDGG-SIIRTSRTNpART 81
Cdd:PRK07085 74 GVILSGGQAPGGHNVIAGlfDGLKKLNPDSKLFGFIGGPLGLLNGKY---IEITEEVIDEYRNTGGfDMIGSGRTK-IET 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 82 PEGVGRVAETLKRHGVDYLITIGGDD----TAFAASRVAKALPGLGLAHVPKTIDNDLPlPSDIDT-FGFSTACNLGKDL 156
Cdd:PRK07085 150 EEQKEACLETVKKLKLDGLVIIGGDDsntnAAILAEYFAKHGCKTQVIGVPKTIDGDLK-NEFIETsFGFDTATKTYSEM 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 157 VRNLMQDAATTER-WFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAIL 235
Cdd:PRK07085 229 IGNISRDALSAKKyWHFIKLMGRSASHIALECALQTHPNICLISEEVAEKKMSLQDIVHYIASVIADRAAKGKNYGVILI 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 236 SEGLAE-------------------------------------KLDLESLG-----P--------VERDQYGNVRLAELD 265
Cdd:PRK07085 309 PEGLIEfipemkslikelnsllaenesefkgldteaqreyiisKLSPESAKlfkslPediarqllLDRDPHGNVQVSKIE 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 266 LGRVLKDRVAGRLRERKVDVTIVGK------DLGYELRCAAPGAHDIQYSRSLGYWATRFLLEGGSNAMVTIQ------- 332
Cdd:PRK07085 389 TEKLLIEMVKKELEKLKPEGKYKGPfsaishFFGYEGRSAFPSNFDADYCYALGYTAALLILNGKTGYMSTIKnltspyt 468
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1125209119 333 --AGRLVPMPFGLLLDPKTGK----IRVRYVDVESEMYQTLWAY 370
Cdd:PRK07085 469 ewIAGAVPLTMMMNMERRHGKekpvIKKALVDLDGPPFKYFAKY 512
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
4-341 |
2.53e-44 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 155.54 E-value: 2.53e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEA-RNHGVRVLGCYDGFKWLVEGDTehVVELTINDLSRIHFDGGSIIRTSRTNPARTP 82
Cdd:TIGR02483 2 IGVLTGGGDCPGLNAVIRGVVRRAiAEYGWEVIGIRDGWRGLLEGDT--VPLLDLEDVRGILPRGGTILGSSRTNPFKYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 83 E-GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKAlpGLGLAHVPKTIDNDLpLPSDIdTFGFSTACNLGKDLVRNLM 161
Cdd:TIGR02483 80 EdGDDKIVANLKELGLDALIAIGGDGTLGIARRLADK--GLPVVGVPKTIDNDL-EATDY-TFGFDTAVEIATEALDRLH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 162 QDAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEflesKITVDRLADilegAIIKRRMHGRDHGVAILSEGLAE 241
Cdd:TIGR02483 156 TTAESHHRVMVVEVMGRHAGWIALHSGIAGGADVILIPEI----PFDIDSVCE----KVRERFARGKRFAIVVVAEGAKP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 242 KLDLESLGPVERDQYGNVRLAelDLGRVLKDRVAGRLrERKVDVTIvgkdLGYELRCAAPGAHDIQYSRSLGYWATRFLL 321
Cdd:TIGR02483 228 KGGEMVVQEGVKDAFGHVRLG--GIGNWLAEEIERRT-GIETRATV----LGHLQRGGSPSAFDRVLATRFGVAAVDLVH 300
|
330 340
....*....|....*....|
gi 1125209119 322 EGGSNAMVTIQAGRLVPMPF 341
Cdd:TIGR02483 301 EGQFGHMVALRGTDIVYVPI 320
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-331 |
8.39e-38 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 142.70 E-value: 8.39e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAA--TIEARNHGVRVLGCYDGFKWLVEGDTehvVELTINDLSRIHFDGG-SIIRTSRTNpAR 80
Cdd:cd00765 75 IGIVLSGGQAPGGHNVISGLfdYLKERAKGSTLYGFKGGPAGILKCDY---IELNAEYIQPYRNTGGfDMICSGRTK-IE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 81 TPEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGLA----HVPKTIDNDLPLPSDIDTFGFSTACNLGKDL 156
Cdd:cd00765 151 TEDQFKQAEETAKKLDLDALVVIGGDDSNTNAALLAENFRSKGLKtrviGVPKTIDGDLKNKEIETSFGFDTATKIYSEL 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 157 VRNLMQDAATTER-WFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAIL 235
Cdd:cd00765 231 IGNVMRDARSTGKyWHFVKLMGRSASHIALECALKTHPNICIISEEVSAQKQTLKNITDYMVDVICKRAELGYNFGVVLV 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 236 SEGLAE-------------------------------------KLDLESLGPV--------------ERDQYGNVRLAEL 264
Cdd:cd00765 311 PEGLIEfipevkeliaelneilanevvefnglwkkklteqslkLFDLLPKGVYlplfieaiqeqlmlERDPHGNVQVSRI 390
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1125209119 265 DLGRVLKDRVAGRLRERKVDVTIVGK------DLGYELRCAAPGAHDIQYSRSLGYWATRFLLEGGSNAMVTI 331
Cdd:cd00765 391 ETEKLLIQMVETRLEKMKQAGAYKGQfmgqshFFGYEGRCAFPSNFDADYCYALGYGAGVLLNSGKTGYISSV 463
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-351 |
3.33e-37 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 136.77 E-value: 3.33e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPARTPE 83
Cdd:cd00763 3 IGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGD---IVPLDRYSVSDIINRGGTFLGSARFPEFKDEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 84 GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAK-ALPGLGLahvPKTIDNDLPlPSDIdTFGFSTACNLGKDLVRNLMQ 162
Cdd:cd00763 80 GQAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEhGFPCVGL---PGTIDNDIP-GTDY-TIGFDTALNTVVEAIDRIRD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 163 DAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEflesKITVDRLADILEGAIIKrrmhGRDHGVAILSEGLaek 242
Cdd:cd00763 155 TSSSHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEA----EFDREEVANRIKAGIER----GKKHAIVVVAEGV--- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 243 ldleslgpverdqYGNVrlaelDLGRVLKDRVAGRLRerkvdVTIvgkdLGYELRCAAPGAHDIQYSRSLGYWATRFLLE 322
Cdd:cd00763 224 -------------YDVD-----ELAKEIEEATGFETR-----ATV----LGHIQRGGSPTAFDRILASRMGAYAVELLLA 276
|
330 340 350
....*....|....*....|....*....|
gi 1125209119 323 GGSNAMVTIQAGRLVPMPF-GLLLDPKTGK 351
Cdd:cd00763 277 GKGGLAVGIQNEQLVHHDIiDAIENMKPFK 306
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
3-369 |
1.42e-30 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 121.30 E-value: 1.42e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 3 TLAILVGGGPAPGINAVIAAATIEA-RNHGV-RVLGCYDGFKWLVEGDTehvVELTINDLSRIHFDGGSIIRTSRTnpar 80
Cdd:PTZ00286 89 KAGIVTCGGLCPGLNVVIRELVMNLiNNYGVkTIYGAKYGYKGLYKEDW---IKLDPKDVKTIHRLGGTILGSSRG---- 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 81 tPEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALP--GLGLAHV--PKTIDNDLPLpSDiDTFGFSTACNLGKDL 156
Cdd:PTZ00286 162 -GFDPKVMVDTLIRHGINILFTLGGDGTHRGALAIYKELRrrKLNISVVgiPKTIDNDIPI-ID-ESFGFQTAVEEAQNA 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 157 VRNLMQDAATTERWF-FVTVMGRRAGHLALGIGGAAGATLTVVAEEFlesKITVDRLADILEGAIIKRRmhgrdHGVAIL 235
Cdd:PTZ00286 239 IRAAYVEAKSAKNGVgIVKLMGRDSGFIALHASVASADVNVCLIPEF---DIPLEGVLEYIEQRLQKKG-----HCVIVV 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 236 SEGLAEklDLESLGPV-ERDQYGNVRLaeLDLGRVLKDRVAGRLRERKVDVTIVGKDLGYELRCAAPGAHDIQYSRSLGY 314
Cdd:PTZ00286 311 AEGAGQ--SLKDADLDlGTDASGNKKL--WDIGVYLKDEITKYLKKKKPEHTVKYIDPSYMIRAVPANAADAKFCTQLAQ 386
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1125209119 315 WATRFLLEGGSNAMVTIQAGRLVPMPFglllDPKTGKIRvRYVDVESEMYQTLWA 369
Cdd:PTZ00286 387 NAVHGAMAGFTGFIIGHVHNNYVMIPI----KEMSGNYR-RRVNPEGRLWQRMLA 436
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
4-323 |
4.85e-29 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 118.36 E-value: 4.85e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAA--TIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPART 81
Cdd:PLN02251 99 IGVVLSGGQAPGGHNVISGIfdYLQEHAKGSVLYGFKGGPAGIMKCK---YVELTAEFIYPYRNQGGFDMICSGRDKIET 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 82 PEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGL-AHV---PKTIDNDLPLPSDIDTFGFSTACNLGKDLV 157
Cdd:PLN02251 176 PEQFKQAEETATKLDLDGLVVIGGDDSNTNACLLAEYFRAKNLkTRVigcPKTIDGDLKSKEVPTSFGFDTACKIYSEMI 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 158 RNLMQDAATTERWF-FVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAILS 236
Cdd:PLN02251 256 GNVMIDARSTGKYYhFVRLMGRAASHITLECALQTHPNITIIGEEVAAKKLTLKNVTDYIVDVICKRAELGYNYGVILIP 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 237 EGL-----------AE------------------KLDLESLG-----P--------VERDQYGNVRLAELDLGRVLKDRV 274
Cdd:PLN02251 336 EGLidfipevqhliAElneilahdvvdeeghwkkKLKPQSLQlfdflPhaiqeqlmLERDPHGNVQVAKIETEKMLIQMV 415
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1125209119 275 AGRLRERKVDVTIVGK------DLGYELRCAAPGAHDIQYSRSLGYWATRFLLEG 323
Cdd:PLN02251 416 ETELEKRKQEGSYKGHfkgqshFFGYEGRCGLPTNFDATYCYALGYGAGALLHSG 470
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
5-316 |
9.68e-28 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 113.04 E-value: 9.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 5 AILVGGGPAPGINAVIAAATIEARNH-GV-RVLGCYDGFKWLVEGDTEHVVELTINDLSRIHFDGGSIIRTSrtnpaRTP 82
Cdd:PRK06830 84 AIVTCGGLCPGLNDVIRAIVLELHHHyGVrRILGIRYGYQGLIPRYGHDPVELTPEVVADIHEFGGTILGSS-----RGP 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 83 EGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGL----AHVPKTIDNDLPLpsdID-TFGFSTACNLGKDLV 157
Cdd:PRK06830 159 QDPEEIVDTLERMNINILFVIGGDGTLRGASAIAEEIERRGLkisvIGIPKTIDNDINF---IQkSFGFETAVEKATEAI 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 158 RnlmqdAATTERWF------FVTVMGRRAGHlalgiggaagatltVVAEEFLESK------ITVDRLAdiLEG-----AI 220
Cdd:PRK06830 236 R-----CAHVEANGapngigLVKLMGRHSGF--------------IAAYAALASKdvnfvlIPEVPFD--LEGpngllAA 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 221 IKRRMHGRDHGVAILSEGLAEKLdLESLGpvERDQYGNVRLAelDLGRVLKDRVAGRLRERKVDVTIVGKDLGYELRCAA 300
Cdd:PRK06830 295 LEKRLAERGHAVIVVAEGAGQEL-FDDTG--ETDASGNPKLG--DIGLFLKDRIKEYFKARGIPINLKYIDPSYIIRSVP 369
|
330
....*....|....*.
gi 1125209119 301 PGAHDIQYSRSLGYWA 316
Cdd:PRK06830 370 ANANDSVYCGFLGQNA 385
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
4-332 |
1.05e-23 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 103.19 E-value: 1.05e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEAR--NHGVRVLGCYDGFKWLVegdTEHVVELTINDLSRIHFDGGSIIRTSRTNPART 81
Cdd:PTZ00287 180 IGIILSGGPAPGGHNVISGIYDYAKryNEQSQVIGFLGGIDGLY---SKNYVTITDSLMNRFRNLGGFNMLWSGRGKVRN 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 82 PEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVA-----KALPgLGLAHVPKTIDNDLPLPSDIDTFGFSTACNLGKDL 156
Cdd:PTZ00287 257 KDDLIAIENIVAKLKLNGLVIIGGDGSNSNAALISeyfaeRQIP-ISIIGIPKTIDGDLKSEAIEISFGFDTATKTYSEV 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 157 VRNLMQDAATTER-WFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAIL 235
Cdd:PTZ00287 336 IGNLCTDVKTGHNvYHVVRVMGRSASHVVLECALQTRPNIVLIGEEVEKENLSLKDIVSNIVNTILKRRSLNKNYGVILI 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 236 SEGL------------------------AEKLD-----LESLGPVERDQY-------GNVRLAELDLGR---VLKDRVAG 276
Cdd:PTZ00287 416 PEGLiefvpemkiligelnvilkegpfdASKLKhsrevWDFLPSIIRDQLlmdrestGYIQVGKIATERliiVLVESELA 495
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1125209119 277 RLRERKVDVTIVGKDLGYELRCAAPGAHDIQYSRSLGYWATRFLLEGGSNAMVTIQ 332
Cdd:PTZ00287 496 KLNDNNLNIQFMAHYLGYEGRCAIPSNFDCNYCYALGYNAALLIDHKKTGYMSIIQ 551
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
2-338 |
1.62e-23 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 102.75 E-value: 1.62e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 2 RTLAILVGGGPAPGINAVIAA--ATIEARNHGVRVLGCYDGfkwlVEG-DTEHVVELTINDLSRIHFDGGSIIRTSRTNP 78
Cdd:PTZ00468 103 RRIGVVLSGGQASGGHNVIAGlmSYIKLCNQSSQLFGFLGG----PEGvYSERYRELTEDDINGILNQGGFNIICSGRHK 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 79 ARTPEGVG---RVAETLKRHGvdyLITIGGDDTAFAASRVAKALPGLGLAHV----PKTIDNDLPLPSDIDTFGFSTACN 151
Cdd:PTZ00468 179 IETEEQMRaslEICEKLKLHG---LVVIGGDDSNTNAAVLAEYFKRNSSSTVvvgcPKTIDGDLKNEVIETSFGYDTAVK 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 152 LGKDLVRNLMqDAATTER--WFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRD 229
Cdd:PTZ00468 256 TYSEQIGSIM-DAIKTEGygYYFVRLMGRSASHITLECGLQTRANMILIGEEIKEENRSLMSIVDEIVEMILKRDSLGKK 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 230 HGVAILSEGLAEKL----------------------------------------DLESLGPVERDQYGNVRLAELDLGRV 269
Cdd:PTZ00468 335 HGIVLLPEGLIEFIpefetlikelnlillktndrkqiidslsqemktlflelpsDVQNQLLLERDPHGNVQVAKIATEEL 414
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1125209119 270 LKDRVAGRLRErkvdvtiVGKD----------LGYELRCAAPGAHDIQYSRSLGYWATRFLLEGGSNAMVTIQAGRLVP 338
Cdd:PTZ00468 415 LVHMAKEKLEE-------VKKDyildnvkthyFGYEGRCALPSNFDASYCFALGHTAAALIDNQRSGYMAVVRKLSLTP 486
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
1-332 |
4.85e-21 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 93.77 E-value: 4.85e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 1 MRTLAILVGGGPAPGINAVIAAATIEARNHGV--RVLGCYDGFKWLVEGDTEHVVELTINDLSRIHFDGGSIIRTSR--- 75
Cdd:PRK14072 3 KGNALYAQSGGPTAVINASAAGVIEEARKHKKigKVYGARNGIIGILDEDLIDLSKESDEALAALAHTPSGALGSCRykl 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 76 TNPARTPEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGLA----HVPKTIDNDLPLpsdID-TFGFSTAC 150
Cdd:PRK14072 83 KSLEEDRAEYERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQLAKKMGYPirciGIPKTIDNDLPG---TDhCPGFGSAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 151 NLGKDLVRNLMQDAA---TTERWFFVTVMGRRAGHlalgiggaagatLTV---VAEEFLES--------KITVDR---LA 213
Cdd:PRK14072 160 KYIATSVLEAALDVAamaNTSKVFILEVMGRHAGW------------LAAaaaLAKQNPDDaphliylpERPFDEekfLA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 214 DIleGAIIKRrmHGRdhGVAILSEGLAEKlD---LESLGPVErDQYGNVRLAelDLGRVLKDRVAGRLRER-KVDVtivg 289
Cdd:PRK14072 228 DV--RAIVKR--YGY--CVVVVSEGIRDA-DgkfIAEAGLAE-DAFGHAQLG--GVAPVLANLIKEKLGKKvHWAV---- 293
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1125209119 290 kdLGYELRCAapgAH-----DIQYSRSLGYWATRFLLEGGSNAMVTIQ 332
Cdd:PRK14072 294 --LDYLQRAA---RHiasktDVEEAYAVGKAAVEYALAGKNGVMPAIR 336
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
4-241 |
8.21e-20 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 91.25 E-value: 8.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 4 LAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPARtpe 83
Cdd:TIGR02478 392 IAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHD---VRELTWSDVEGWVGEGGSELGTNRSLPGD--- 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 84 GVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKA--------LPglgLAHVPKTIDNDLPlPSDIdTFGFSTACNLGKD 155
Cdd:TIGR02478 466 DLGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDAArekypafrIP---MVVIPATISNNVP-GTEY-SLGSDTALNEITE 540
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 156 LVRNLMQDA-ATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEflesKITVDRLA-DILEgaiIKRRM-HGRDHGV 232
Cdd:TIGR02478 541 YCDNIKQSAsASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEE----GISLKDLQeDIEH---LKETFaEGRAGKL 613
|
....*....
gi 1125209119 233 AILSEGLAE 241
Cdd:TIGR02478 614 ILRNEKASK 622
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
2-340 |
1.56e-19 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 90.48 E-value: 1.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 2 RTLAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtEHVVELTINDLSRIHFDGGSIIRTSRTNPART 81
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDGG-DNIEEAQWEDVRGILSLGGTIIGTARCKEFRE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 82 PEGVGRVAETLKRHGVDYLITIGGDDTAFAA---------------------SRVAKALPGLGLAHVPKTIDNDLPlPSD 140
Cdd:TIGR02478 80 RPGRLKAARNLVSNGIDALVVIGGDGSLTGAdlfreewpslleelvdtgkitAEQAEEHRHLTIVGLVGSIDNDMC-GTD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 141 IdTFGFSTACNLGKDLVRNLMQDAATTERWFFVTVMGRRAGHlalgiggaagatLTVVAEE-------FLESKITVDRLA 213
Cdd:TIGR02478 159 M-TIGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGY------------LALMAAIatgadyvFIPERPPEEGWE 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 214 DILEGAIIKRRMHGRDHGVAILSEGLAEKldleSLGPVERDQYGNVRLAELDLgrvlkdrvagrlrerKVDVTIvgkdLG 293
Cdd:TIGR02478 226 DQLCHKLKRNRKAGKRKTIVIVAEGAIDR----DLNPITSEDVKDVLVERLGL---------------DTRITV----LG 282
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1125209119 294 YELRCAAPGAHDIQYSRSLGYWATRFLLEGGSNA---MVTIQAGRLVPMP 340
Cdd:TIGR02478 283 HVQRGGAPSAFDRILATRQGVEAVLAVLESTPETpspVISLRGNKIVRKP 332
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
2-340 |
1.37e-18 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 85.89 E-value: 1.37e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 2 RTLAILVGGGPAPGINAVIAAATIEAR-NHGVRVLGCYDGFKWLVEgDTEHVVELTINDLSRIHFDGGSII-RTSRTNPA 79
Cdd:PRK14071 5 KRIGILTSGGDCAGLNAVIRAVVHRARgTYGWEVIGIRDATQGLMA-RPPQYIELDLDQVDDLLRMGGTILgTTNKGDPF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 80 RTPEGVG-------RVAETLKRHGVDYLITIGGDDTaFAASRVAKALPGLGLAHVPKTIDNDLPLPSDidTFGFSTACNL 152
Cdd:PRK14071 84 AFPMPDGslrdrsqEIIDGYHSLGLDALIGIGGDGS-LAILRRLAQQGGINLVGIPKTIDNDVGATEV--SIGFDTAVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 153 GKDLVRNLMQDAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAeeflESKITVDRLADIlegaIIKRRMHGRDHGV 232
Cdd:PRK14071 161 ATEALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIP----EIPYTLENVCKK----IRERQEEGKNFCL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 233 AILSEGLaekLDLESLGPVERDQYGNVRLAelDLGRVLKDRVAGRL-RERKVDVtivgkdLGYELRCAAPGAHDIQYSRS 311
Cdd:PRK14071 233 VVVSEAV---RTEEGEQVTKTQALGEDRYG--GIGQYLAEQIAERTgAETRVTV------LGHIQRGGIPSPRDRLLASA 301
|
330 340
....*....|....*....|....*....
gi 1125209119 312 LGYWATRFLLEGGSNAMVTIQAGRLVPMP 340
Cdd:PRK14071 302 FGVAAVDLIAQGKFDRMVAWQNRQVVSVP 330
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
1-325 |
5.14e-18 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 84.67 E-value: 5.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 1 MRTLAILVGGGPAPGINAVIAAaTIEARNH---GVRVLGCYDGFKWLVEGDTehvveLTINDLSR-----IHFDGGSIIR 72
Cdd:PRK06555 3 VKKVALLTAGGLAPCLSSAVGG-LIERYTEiapEVEIIAYRSGYQGLLLGDS-----IEITPAVRanaglLHRYGGSPIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 73 TSRTNPARTPEGVGR------------VAETLKRHGVDYLITIGGDDTAFAASRVAKALP--GLGLAHV--PKTIDNDL- 135
Cdd:PRK06555 77 NSRVKLTNVADCVKRglvkegenplkvAAERLAADGVDILHTIGGDDTNTTAADLAAYLAenGYDLTVVglPKTIDNDVv 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 136 PLPSdidTFGFSTACNLGKDLVRNLMQDAATTERWFFV-TVMGRRAGHLALGIGGAAGATLtvVAEEFLESKITVDRLAD 214
Cdd:PRK06555 157 PIRQ---SLGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLTAATARAYREWL--DRQEYVPGFGLSAERWD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 215 I-------------LEGAIIKRRMHGRDHGVAILSEG------LAEkldLESLG-PVERDQYGNVRLAELDLGRVLKDRV 274
Cdd:PRK06555 232 IhavylpemafdleAEAERLKAVMDEVGNVNIFLSEGagldaiVAE---MEAAGeEVKRDAFGHVKLDTINPGAWFAKQF 308
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1125209119 275 AGRLRERKvdvTIVGKDlGYELRCAAPGAHDIQYSRSLGYWATRFLLEGGS 325
Cdd:PRK06555 309 AELLGAEK---VMVQKS-GYFARSAPANAEDLRLIKSMVDLAVECALRGVS 355
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-340 |
2.77e-15 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 77.56 E-value: 2.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 2 RTLAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtEHVVELTINDLSRIHFDGGSIIRTSRTNPART 81
Cdd:cd00764 4 KAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGG-DYIKQAEWESVSNWLQEGGTIIGSARCKEFRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 82 PEGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGL---------------------GLAHVPKTIDNDLplpSD 140
Cdd:cd00764 83 REGRLQAAYNLIQRGITNLCVIGGDGSLTGADLFRSEWPSLleelvkdgkiteeevakyqhlNIVGMVGSIDNDF---CG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 141 ID-TFGFSTACNLGKDLVRNLMQDAATTERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITvDRLADILEga 219
Cdd:cd00764 160 TDmTIGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEDGWE-DQMCRRLS-- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 220 iiKRRMHGRDHGVAILSEGLAEKldleSLGPVERDQYGNVRLAELDLgrvlkdrvagrlrerKVDVTIvgkdLGYELRCA 299
Cdd:cd00764 237 --EHRSRGKRLNIIIVAEGAIDD----QLKPITSEDVKDLVVERLGL---------------DTRVTT----LGHVQRGG 291
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1125209119 300 APGAHDIQYSRSLGYWATRFLLEGGSNA---MVTIQAGRLVPMP 340
Cdd:cd00764 292 TPSAFDRILASLMGVEAVMALLEATPDTpacVVSLNGNKAVRLP 335
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
5-341 |
1.40e-14 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 74.78 E-value: 1.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 5 AILVGGGPAPGINAVIAAATIEARN-HGV-RVLGCYDGFKWLVEGDTEHVVELTINDlsrIHFDGGSIIRTSRTNpartp 82
Cdd:PLN02564 91 CIVTCGGLCPGLNTVIREIVCGLSYmYGVtRILGIDGGYRGFYSRNTIPLTPKVVND---IHKRGGTILGTSRGG----- 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 83 EGVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGL----AHVPKTIDNDLPLpsdID-TFGFSTACNLGKDLV 157
Cdd:PLN02564 163 HDTSKIVDSIQDRGINQVYIIGGDGTQKGASVIYEEIRRRGLkvavAGIPKTIDNDIPV---IDkSFGFDTAVEEAQRAI 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 158 RNLMQDAATTERWF-FVTVMGRRAGHLALGIGGAAGATLTVVAEE---FLESKitvdrlADILEgaIIKRRMHGRDHGVA 233
Cdd:PLN02564 240 NAAHVEAESVENGIgLVKLMGRYSGFIAMYATLASRDVDCCLIPEspfYLEGK------GGLFE--FIEKRLKENGHMVI 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 234 ILSEGLAEKLDLESLGPVE-RDQYGNVRLaeLDLGRVLKDRVAGR-LRERKVDVTIVGKDLGYELRCAAPGAHDIQYSRS 311
Cdd:PLN02564 312 VVAEGAGQDLIAESMESSDlQDASGNKLL--LDVGLWLSQKIKDHfTKVKKMPINLKYIDPTYMIRAIPSNASDNVYCTL 389
|
330 340 350
....*....|....*....|....*....|
gi 1125209119 312 LGYWATRFLLEGGSNAMVTIQAGRLVPMPF 341
Cdd:PLN02564 390 LAHSAVHGAMAGYTGFTVGPVNGRHAYIPF 419
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-182 |
1.54e-14 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 75.24 E-value: 1.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 3 TLAILVGGGPAPGINAVIAAATIEARNHGVRVLGCYDGFKWLVEGDtehVVELTINDLSRIHFDGGSIIRTSRTNPArtp 82
Cdd:cd00764 391 NIAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQ---IVELGWIDVGGWTGRGGSELGTKRTLPK--- 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 83 EGVGRVAETLKRHGVDYLITIGGDDtAFAA----SRVAKALPGLGLAHV--PKTIDNDLPlPSDIdTFGFSTACNLGKDL 156
Cdd:cd00764 465 KDLETIAYNFQKYGIDGLIIVGGFE-AYKGllqlREAREQYEEFCIPMVliPATVSNNVP-GTDF-SLGSDTALNALMKY 541
|
170 180
....*....|....*....|....*..
gi 1125209119 157 VRNLMQDAATTE-RWFFVTVMGRRAGH 182
Cdd:cd00764 542 CDRIKQSASGTKrRVFIVETMGGYCGY 568
|
|
| PLN03028 |
PLN03028 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
10-331 |
2.10e-14 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 215543 Cd Length: 610 Bit Score: 74.43 E-value: 2.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 10 GGPAPGINAVIAAA--TIEARNHGVRVLGCYDGFKWLVEGDTehvVELTINDLSRIHFDGGSIIRTSRTNPARTPEGVGR 87
Cdd:PLN03028 88 GRQSPGGHNVIWGLhdALKAHNPNSVLLGFLGGTEGLFAQKT---LEITDDVLSTYKNQGGYDLLGRTKDQIRTTEQVNA 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 88 VAETLKRHGVDYLITIGG----DDTAFAASRVAKALPGLGLAHVPKTIDNDLPLPSDIDTFGFSTACNLGKDLVRNLMQD 163
Cdd:PLN03028 165 ALAACEALKLDGLVIIGGvtsnTDAAQLAETFAEAKCKTKVVGVPVTLNGDLKNQFVETNVGFDTICKVNSQLISNVCTD 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 164 AATTERWF-FVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAILSEGLAEK 242
Cdd:PLN03028 245 ALSAEKYYyFIRLMGRKASHVALECALQSHPNMVILGEEVAASKLTLFDITKQICDAVQARAEQDKNHGVILIPEGLIES 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 243 LD---------------------------------LESLGPVERDQY-------GNVRLAELDLGRVLKDRVAGRLRERK 282
Cdd:PLN03028 325 IPevyallqeihgllkqgvsvdnissqlspwasalFEFLPPFIKKQLllhpesdDSAQLSQIETEKLLAQLVETEMNKRT 404
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1125209119 283 VDVTIVGKD-------LGYELRCAAPGAHDIQYSRSLGYWATRFLLEGGSNAMVTI 331
Cdd:PLN03028 405 KEGTYKGKKfnaichfFGYQARGSLPSKFDCDYAYVLGHICYHILAAGLNGYMATV 460
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
5-181 |
6.00e-12 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 66.37 E-value: 6.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 5 AILVGGGPAPGINAVIAAATIEARNHGVR-VLGCYDGFKWLVEgDTEHVVELTINDLSRIHFDGGSIIRTSRTNPArtpe 83
Cdd:PLN02884 57 AIVTCGGLCPGLNDVIRQIVFTLEIYGVKnIVGIPFGYRGFFE-KGLSEMPLSRKVVQNIHLSGGSLLGVSRGGAK---- 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 84 gVGRVAETLKRHGVDYLITIGGDDTAFAASRVAKALPGLGL----AHVPKTIDNDLPLpsdID-TFGFSTACNLGKDLVR 158
Cdd:PLN02884 132 -TSDIVDSIEARGINMLFVLGGNGTHAGANAIHNECRKRKMkvsvVGVPKTIDNDILL---MDkTFGFDTAVEEAQRAIN 207
|
170 180
....*....|....*....|....
gi 1125209119 159 NLMQDAATTERWF-FVTVMGRRAG 181
Cdd:PLN02884 208 SAYIEAHSAYHGIgLVKLMGRSSG 231
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
83-239 |
2.83e-05 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 46.18 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 83 EGVGRVAETLKRHGVDYLITIGGDDTAFAASRVA-----KALPgLGLAHVPKTIDNDLpLPSDIDT-FGFSTACNLGKDL 156
Cdd:PTZ00287 915 ENRNKVCETVTNLQLNGLVMPGSNVTITEAALLAeyfleKKIP-TSVVGIPLTGSNNL-IHELIETcVGFDSSTKVYASL 992
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 157 VRNLMQDAATTER-WFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLESKITVDRLADILEGAIIKRRMHGRDHGVAIL 235
Cdd:PTZ00287 993 IGNVLTDAVSMPKyWHFIRLMGRSPSHEVLECALQTHPNMVIISEEYGAADKTLWRVVQDIADVVCARAELGKNYGTVLI 1072
|
....
gi 1125209119 236 SEGL 239
Cdd:PTZ00287 1073 PDAL 1076
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
127-243 |
4.66e-04 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 42.27 E-value: 4.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209119 127 VPKTIDNDLPLPSdIDT-FGFSTACNLGKDLVRNLMQDAAT-TERWFFVTVMGRRAGHLALGIGGAAGATLTVVAEEFLE 204
Cdd:PTZ00468 840 VPVCLENSISHQM-IETcIGFDSVTKSISTLVGNLLTDSASaTKYWYFMKMIGDKTSNVALEVGIQTHPNLVVIPERYAD 918
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1125209119 205 SK----------ITVDRLADILEGAIIKRRMHGRDHGVAILSEGLAEKL 243
Cdd:PTZ00468 919 SKlsvygsemagVTLDDIITEICDIICLRSNQGNNFGGLLVSEGLFDQV 967
|
|
| |
