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Conserved domains on  [gi|1125209211|gb|OLB60458|]
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hypothetical protein AUI13_00190 [Gemmatimonadetes bacterium 13_2_20CM_2_69_23]

Protein Classification

NADH-quinone oxidoreductase subunit C( domain architecture ID 10448334)

NADH-quinone oxidoreductase subunit C (NuoC) is part of the connecting domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NuoC COG0852
NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) [Energy production and conversion]; ...
 5-152 1.12e-60

NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) [Energy production and conversion]; NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) is part of the Pathway/BioSystem: NADH dehydrogenase


:

Pssm-ID: 440613 [Multi-domain]  Cd Length: 164  Bit Score: 186.58  E-value: 1.12e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   5 VDALRATFGPAIGRALESCGDTIVYVGREALLGVMAWLRDTPQqtYDYLVDITAVEYRDRERPLEVVYNLRSLTRRADLR 84
Cdd:COG0852     8 LEALEEKFGDAVLEVEEARGELTLTVPPEDLVDVARFLRDDLG--FDHLSDLTGVDYPERGDRFEVVYHLLSLTHNRRLR 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1125209211  85 VKVELDPQgDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRGR 152
Cdd:COG0852    86 LKVFVPRD-DPVVPSVTDVWPGANWHEREAYDMFGIVFEGHPDLRRILLPEDW-EGHPLRKDFPLEGY 151
 
Name Accession Description Interval E-value
NuoC COG0852
NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) [Energy production and conversion]; ...
 5-152 1.12e-60

NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) [Energy production and conversion]; NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440613 [Multi-domain]  Cd Length: 164  Bit Score: 186.58  E-value: 1.12e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   5 VDALRATFGPAIGRALESCGDTIVYVGREALLGVMAWLRDTPQqtYDYLVDITAVEYRDRERPLEVVYNLRSLTRRADLR 84
Cdd:COG0852     8 LEALEEKFGDAVLEVEEARGELTLTVPPEDLVDVARFLRDDLG--FDHLSDLTGVDYPERGDRFEVVYHLLSLTHNRRLR 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1125209211  85 VKVELDPQgDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRGR 152
Cdd:COG0852    86 LKVFVPRD-DPVVPSVTDVWPGANWHEREAYDMFGIVFEGHPDLRRILLPEDW-EGHPLRKDFPLEGY 151
Complex1_30kDa pfam00329
Respiratory-chain NADH dehydrogenase, 30 Kd subunit;
28-152 2.17e-53

Respiratory-chain NADH dehydrogenase, 30 Kd subunit;


Pssm-ID: 459763 [Multi-domain]  Cd Length: 121  Bit Score: 166.88  E-value: 2.17e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  28 VYVGREALLGVMAWLRDTPQQtYDYLVDITAVEYRDRERpLEVVYNLRSLTRRADLRVKVELDPqgDLTVDSVVSLWRGA 107
Cdd:pfam00329   1 VTVDPEDLLEVARFLRDDELG-FDHLSDLTGVDYPEEGR-FEVVYHLLSITHNVRVRVKVPLED--DPVVPSVTDIWPGA 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1125209211 108 DWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRGR 152
Cdd:pfam00329  77 NWYEREVYDMFGIVFEGHPDLRRILLPEDW-EGHPLRKDFPLTGY 120
NuoC_fam TIGR01961
NADH (or F420H2) dehydrogenase, subunit C; This model describes the C subunit of the NADH ...
 28-151 1.18e-46

NADH (or F420H2) dehydrogenase, subunit C; This model describes the C subunit of the NADH dehydrogenase complex I in bacteria, as well as many instances of the corresponding mitochondrial subunit (NADH dehydrogenase subunit 9) and of the F420H2 dehydrogenase in Methanosarcina. Complex I contains subunits designated A-N. This C subunit often occurs as a fusion protein with the D subunit. This model excludes the NAD(P)H and plastoquinone-dependent form of chloroplasts and [Energy metabolism, Electron transport]


Pssm-ID: 273897 [Multi-domain]  Cd Length: 121  Bit Score: 149.69  E-value: 1.18e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  28 VYVGREALLGVMAWLRDTPQQtYDYLVDITAVEYRDRERpLEVVYNLRSLTRRADLRVKVELDPqgDLTVDSVVSLWRGA 107
Cdd:TIGR01961   3 VWIKKEQLLEVLTFLKDPALG-FELLTDVSGVDYPKEKR-FEVVYHLLSIKKNRRIRLKVRLSE--DDPVPSLTSVFPTA 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1125209211 108 DWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRG 151
Cdd:TIGR01961  79 NWYERETYDMYGIVFDGHPDLRRILMPDDF-EGHPLRKDYPLTG 121
PRK06074 PRK06074
NADH dehydrogenase subunit C; Provisional
 5-151 4.92e-45

NADH dehydrogenase subunit C; Provisional


Pssm-ID: 235691 [Multi-domain]  Cd Length: 189  Bit Score: 147.75  E-value: 4.92e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   5 VDALRATFGPAIGRALESCGDTIVYVGREALLGVMAWLRDTPQQTYDYLVDITAVEYRDRERPLEVVYNLRSLTRRADLR 84
Cdd:PRK06074    8 VAKLLEKLPDAIGKVTVAFGELTLKVPAEKILEVLTFLRDDPELRFEQLIDLTGVDYPERGKRFEVVYHLLSYKHNVRLR 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1125209211  85 VKVELDPqgDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRG 151
Cdd:PRK06074   88 VKVRAPE--DPVVPSVVDIWPSANWYEREAYDLYGIVFEGHPDLRRILTDYGF-EGHPLRKDFPLTG 151
 
Name Accession Description Interval E-value
NuoC COG0852
NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) [Energy production and conversion]; ...
 5-152 1.12e-60

NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) [Energy production and conversion]; NADH:ubiquinone oxidoreductase 27 kD subunit (chain C) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440613 [Multi-domain]  Cd Length: 164  Bit Score: 186.58  E-value: 1.12e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   5 VDALRATFGPAIGRALESCGDTIVYVGREALLGVMAWLRDTPQqtYDYLVDITAVEYRDRERPLEVVYNLRSLTRRADLR 84
Cdd:COG0852     8 LEALEEKFGDAVLEVEEARGELTLTVPPEDLVDVARFLRDDLG--FDHLSDLTGVDYPERGDRFEVVYHLLSLTHNRRLR 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1125209211  85 VKVELDPQgDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRGR 152
Cdd:COG0852    86 LKVFVPRD-DPVVPSVTDVWPGANWHEREAYDMFGIVFEGHPDLRRILLPEDW-EGHPLRKDFPLEGY 151
Complex1_30kDa pfam00329
Respiratory-chain NADH dehydrogenase, 30 Kd subunit;
28-152 2.17e-53

Respiratory-chain NADH dehydrogenase, 30 Kd subunit;


Pssm-ID: 459763 [Multi-domain]  Cd Length: 121  Bit Score: 166.88  E-value: 2.17e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  28 VYVGREALLGVMAWLRDTPQQtYDYLVDITAVEYRDRERpLEVVYNLRSLTRRADLRVKVELDPqgDLTVDSVVSLWRGA 107
Cdd:pfam00329   1 VTVDPEDLLEVARFLRDDELG-FDHLSDLTGVDYPEEGR-FEVVYHLLSITHNVRVRVKVPLED--DPVVPSVTDIWPGA 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1125209211 108 DWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRGR 152
Cdd:pfam00329  77 NWYEREVYDMFGIVFEGHPDLRRILLPEDW-EGHPLRKDFPLTGY 120
NuoC_fam TIGR01961
NADH (or F420H2) dehydrogenase, subunit C; This model describes the C subunit of the NADH ...
 28-151 1.18e-46

NADH (or F420H2) dehydrogenase, subunit C; This model describes the C subunit of the NADH dehydrogenase complex I in bacteria, as well as many instances of the corresponding mitochondrial subunit (NADH dehydrogenase subunit 9) and of the F420H2 dehydrogenase in Methanosarcina. Complex I contains subunits designated A-N. This C subunit often occurs as a fusion protein with the D subunit. This model excludes the NAD(P)H and plastoquinone-dependent form of chloroplasts and [Energy metabolism, Electron transport]


Pssm-ID: 273897 [Multi-domain]  Cd Length: 121  Bit Score: 149.69  E-value: 1.18e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  28 VYVGREALLGVMAWLRDTPQQtYDYLVDITAVEYRDRERpLEVVYNLRSLTRRADLRVKVELDPqgDLTVDSVVSLWRGA 107
Cdd:TIGR01961   3 VWIKKEQLLEVLTFLKDPALG-FELLTDVSGVDYPKEKR-FEVVYHLLSIKKNRRIRLKVRLSE--DDPVPSLTSVFPTA 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1125209211 108 DWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRG 151
Cdd:TIGR01961  79 NWYERETYDMYGIVFDGHPDLRRILMPDDF-EGHPLRKDYPLTG 121
PRK06074 PRK06074
NADH dehydrogenase subunit C; Provisional
 5-151 4.92e-45

NADH dehydrogenase subunit C; Provisional


Pssm-ID: 235691 [Multi-domain]  Cd Length: 189  Bit Score: 147.75  E-value: 4.92e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   5 VDALRATFGPAIGRALESCGDTIVYVGREALLGVMAWLRDTPQQTYDYLVDITAVEYRDRERPLEVVYNLRSLTRRADLR 84
Cdd:PRK06074    8 VAKLLEKLPDAIGKVTVAFGELTLKVPAEKILEVLTFLRDDPELRFEQLIDLTGVDYPERGKRFEVVYHLLSYKHNVRLR 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1125209211  85 VKVELDPqgDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRG 151
Cdd:PRK06074   88 VKVRAPE--DPVVPSVVDIWPSANWYEREAYDLYGIVFEGHPDLRRILTDYGF-EGHPLRKDFPLTG 151
PRK11742 PRK11742
bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional
 5-169 3.16e-38

bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional


Pssm-ID: 236965 [Multi-domain]  Cd Length: 575  Bit Score: 138.52  E-value: 3.16e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   5 VDALRATFGPAIgRALESCGDTI--VYVGREALLGVMAWLRDTPQqTYDYLVDITAVEYRDR-------ERPLEVVYNLR 75
Cdd:PRK11742    2 IGELRNRFGPDA-FTVQATRTGIpvVWVKREQLLEVLRFLRKLPK-PYVMLFDLHGIDERLRthreglpAADFTVFYHLI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  76 SLTRRADLRVKVELdPQGDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLRG---- 151
Cdd:PRK11742   80 SIERNRDIMLKVAL-SENDLHVPTITKIFPNANWYERETWDMFGITFDGHPHLRRILMPPTW-EGHPLRKDYPARAtefd 157

                         170       180
                  ....*....|....*....|..
gi 1125209211 152 --RFSRAEQVR--QALAAQPEA 169
Cdd:PRK11742  158 pfELTKAKQDLemEALRFKPEE 179
PRK07785 PRK07785
NADH dehydrogenase subunit C; Provisional
 5-151 3.21e-32

NADH dehydrogenase subunit C; Provisional


Pssm-ID: 181115 [Multi-domain]  Cd Length: 235  Bit Score: 116.24  E-value: 3.21e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   5 VDALRA---TFGPAIGRALESCGDTIVYVGREALLGVMAWLRDTPQQTYDYLVDITAVEY-RDRERPLEVVYNLRSLTRR 80
Cdd:PRK07785   67 ADRLEEalpEFADAIERVVVDRGELTLHVRREHLVEVAQTLRDDPALRFELCLGVSGVHYpHDTGRELHAVYHLTSITHN 146

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1125209211  81 ADLRVKVELdPQGDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILM---WetyaEGYPLRKDFPLRG 151
Cdd:PRK07785  147 RRIRLEVAV-PDADPHIPSLVSVYPTNDWHERETYDFFGIVFDGHPALTRIEMpddW----VGHPQRKDYPLGG 215
PRK07735 PRK07735
NADH-quinone oxidoreductase subunit C;
30-147 2.77e-28

NADH-quinone oxidoreductase subunit C;


Pssm-ID: 236081 [Multi-domain]  Cd Length: 430  Bit Score: 109.68  E-value: 2.77e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  30 VGREALLGVMAWLRDTPQQTYDYLVDITAVEYRDRerpLEVVYNLRSLTRRADLRVKVELD---PQgdltVDSVVSLWRG 106
Cdd:PRK07735  311 VEPEKYYEVAELLRFHEQLAFDYLSELHGTDFVTH---MEVYVHLYSYGKRQSVAVKVKLDreaPQ----VESVTPLWKG 383

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1125209211 107 ADWLEREVYDMFGITFRGHPDLRRILMWETYAeGYPLRKDF 147
Cdd:PRK07735  384 ANWPEREAYDLLGIVFKGHPNLSRILLPDDWV-GHPLRKDY 423
PRK08491 PRK08491
NADH-quinone oxidoreductase subunit C;
50-151 5.34e-26

NADH-quinone oxidoreductase subunit C;


Pssm-ID: 181449  Cd Length: 263  Bit Score: 100.90  E-value: 5.34e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  50 YDYLVDITAVEYRDRERPLEVVYNLRSLTRRADLRVKVELdPQGDlTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLR 129
Cdd:PRK08491   80 YECLSEMSAIDFLAKKGGFEVFYQLLSMSKRKRVRVKCFL-KEKE-ALQSVSFLFKSANWSEREMYDMFGIVINNHPYLK 157

                          90       100
                  ....*....|....*....|....*
gi 1125209211 130 RILM---WetyaEGYPLRKDFPLRG 151
Cdd:PRK08491  158 RILMpddW----VGHPLLKSYPLKG 178
PRK13292 PRK13292
NADH-quinone oxidoreductase subunit B/C/D;
8-150 2.66e-25

NADH-quinone oxidoreductase subunit B/C/D;


Pssm-ID: 183955 [Multi-domain]  Cd Length: 788  Bit Score: 102.55  E-value: 2.66e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   8 LRATFGPAIgRALESCGDTIVYVGREALLG-VMAWLRDTPQQTYDYLVDITAVE---YRDRER--PLEVVYNLRSLTRRA 81
Cdd:PRK13292  228 LEGAFGDDV-RLDEGATDMLTYRCPPELVPeVLRHLKKRASSPFRRLEDLAAVDescRRDREKfpDFTVNYHLLSFDTPG 306

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  82 DLRVKVELdpQGDL-TVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYaEGYPLRKDFPLR 150
Cdd:PRK13292  307 HVRIKTEL--RGRTpELPSATGVFPAANWYEREAFDMFGIRFAGHPNLRRILMPPDW-EGHPLRKEHPFR 373
PRK12494 PRK12494
NAD(P)H-quinone oxidoreductase subunit J;
67-147 5.81e-25

NAD(P)H-quinone oxidoreductase subunit J;


Pssm-ID: 183557 [Multi-domain]  Cd Length: 172  Bit Score: 95.79  E-value: 5.81e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  67 PLEVVYNLRSLTRRAD----LRVKVELdPQGDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYAeGYP 142
Cdd:PRK12494   78 ELVSFYHLIKVSDNADkpreVRLKVFL-PRDDPRVPSVYWIWKGADWQERETYDMYGINFEGHPNLKRILMPEDWV-GWP 155


                  ....*
gi 1125209211 143 LRKDF 147
Cdd:PRK12494  156 LRKDY 160
HycE1 COG3262
Ni,Fe-hydrogenase III component G [Energy production and conversion];
3-148 3.10e-17

Ni,Fe-hydrogenase III component G [Energy production and conversion];


Pssm-ID: 442493 [Multi-domain]  Cd Length: 523  Bit Score: 79.22  E-value: 3.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211   3 PSVDALRATFGPAIGRALESCGDTI-VYVGREALLGVMAWLRDtpqQTYDYLVDITAVEYRDRERPLEVVYNLRSLTRRA 81
Cdd:COG3262     2 TRPEELRARFGGSILERRWVRPNEVwVEVDREDLPELAEFLAE---GGGGRLAALWGNDERELGGGFAVYYVFALEGEGA 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1125209211  82 DLRVKVELDPQgDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYAEG-YPLRKDFP 148
Cdd:COG3262    79 LVTLKVSVPKD-DPVFPSITDLFPAASWYEREIRDLFGIVPEGHPDPRRLVLHDDWPEGiYPLRKDFK 145
ndhJ CHL00012
NADH dehydrogenase subunit J
 67-147 2.37e-16

NADH dehydrogenase subunit J


Pssm-ID: 176955 [Multi-domain]  Cd Length: 158  Bit Score: 72.81  E-value: 2.37e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125209211  67 PLEVVYNLRSLTRRAD----LRVKVELdPQGDLTVDSVVSLWRGADWLEREVYDMFGITFRGHPDLRRILMWETYAeGYP 142
Cdd:CHL00012   64 LLASVYHLTRIQYGVDqpeeVCIKVFV-PRKNPRIPSVFWVWKSADFQERESYDMLGISYDNHPRLKRILMPESWI-GWP 141


                  ....*
gi 1125209211 143 LRKDF 147
Cdd:CHL00012  142 LRKDY 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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