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Conserved domains on  [gi|1144870553|gb|ONZ12584|]
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hypothetical protein A8F40_00030 [Burkholderia cenocepacia]

Protein Classification

transcriptional regulator( domain architecture ID 11459460)

transcriptional regulator containing a PAS and a DNA-binding helix-turn-helix domain

Gene Ontology:  GO:0003677|GO:0140110

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
6-210 1.10e-82

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


:

Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 244.75  E-value: 1.10e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553   6 SPVKDLLLTRYAPIADGIAALFFPYAEVVIHDLHDQ--TVLYLAN-NLSKREVGD---DSALEEIDHSARE--RVIGPYE 77
Cdd:COG2964     2 SKEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPehSIVAIANgHVSGRKVGDpitDLGLELLKDGAYEdpDVIGNYE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553  78 KLNWDGRRMRCVSNVLFDDEGRAAGMMCINFNIAVFDEVRATLDLFIKGAGVVAQPDELFRDDWQERINTFLHGWLRERQ 157
Cdd:COG2964    82 TRTKDGRLLKSSTIFIRDEKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDEIIDEALAEVG 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1144870553 158 VGLNGLTREHRRELVEALYAEGAFRGKSAANYVANVLGMGRATVYKHLKHLKE 210
Cdd:COG2964   162 KPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
6-210 1.10e-82

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 244.75  E-value: 1.10e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553   6 SPVKDLLLTRYAPIADGIAALFFPYAEVVIHDLHDQ--TVLYLAN-NLSKREVGD---DSALEEIDHSARE--RVIGPYE 77
Cdd:COG2964     2 SKEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPehSIVAIANgHVSGRKVGDpitDLGLELLKDGAYEdpDVIGNYE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553  78 KLNWDGRRMRCVSNVLFDDEGRAAGMMCINFNIAVFDEVRATLDLFIKGAGVVAQPDELFRDDWQERINTFLHGWLRERQ 157
Cdd:COG2964    82 TRTKDGRLLKSSTIFIRDEKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDEIIDEALAEVG 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1144870553 158 VGLNGLTREHRRELVEALYAEGAFRGKSAANYVANVLGMGRATVYKHLKHLKE 210
Cdd:COG2964   162 KPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
13-119 1.84e-36

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 123.78  E-value: 1.84e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553  13 LTRYAPIADGIAALFFPYAEVVIHDL--HDQTVLYLAN-NLSKREVGD---DSALEEIDHSARER--VIGPYEKLNWDGR 84
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLrdPEHSIVAIANgHVTGRKVGDpitDLALELLKQEEYEEkdYLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1144870553  85 RMRCVSNVLFDDEGRAAGMMCINFNIAVFDEVRAT 119
Cdd:pfam08348  81 ILKSSTIFIRDEDGKIIGLLCINFDITALLAAQNA 115
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
6-210 1.10e-82

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 244.75  E-value: 1.10e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553   6 SPVKDLLLTRYAPIADGIAALFFPYAEVVIHDLHDQ--TVLYLAN-NLSKREVGD---DSALEEIDHSARE--RVIGPYE 77
Cdd:COG2964     2 SKEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPehSIVAIANgHVSGRKVGDpitDLGLELLKDGAYEdpDVIGNYE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553  78 KLNWDGRRMRCVSNVLFDDEGRAAGMMCINFNIAVFDEVRATLDLFIKGAGVVAQPDELFRDDWQERINTFLHGWLRERQ 157
Cdd:COG2964    82 TRTKDGRLLKSSTIFIRDEKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDEIIDEALAEVG 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1144870553 158 VGLNGLTREHRRELVEALYAEGAFRGKSAANYVANVLGMGRATVYKHLKHLKE 210
Cdd:COG2964   162 KPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
13-119 1.84e-36

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 123.78  E-value: 1.84e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1144870553  13 LTRYAPIADGIAALFFPYAEVVIHDL--HDQTVLYLAN-NLSKREVGD---DSALEEIDHSARER--VIGPYEKLNWDGR 84
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLrdPEHSIVAIANgHVTGRKVGDpitDLALELLKQEEYEEkdYLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1144870553  85 RMRCVSNVLFDDEGRAAGMMCINFNIAVFDEVRAT 119
Cdd:pfam08348  81 ILKSSTIFIRDEDGKIIGLLCINFDITALLAAQNA 115
HTH_22 pfam13309
HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding ...
144-206 5.35e-19

HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding domain.


Pssm-ID: 463841 [Multi-domain]  Cd Length: 63  Bit Score: 77.12  E-value: 5.35e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1144870553 144 RINTFLHGWLRERQVGLNGLTREHRRELVEALYAEGAFRGKSAANYVANVLGMGRATVYKHLK 206
Cdd:pfam13309   1 LLDSIIDEVLADVGKPPARLTKEEKREIVRALDEKGAFLLKGAVEKVAKRLGVSRATVYNYLR 63
COG1777 COG1777
Predicted transcriptional regulator, ArsR family [Transcription];
166-210 8.38e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441383  Cd Length: 113  Bit Score: 35.01  E-value: 8.38e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1144870553 166 EHRRELVEALYAEGAFrgksaANYVANVLGMGRATVYKHLKHLKE 210
Cdd:COG1777    17 PTRRRILALLSEEPAY-----VSELARELGVSRQAVYKHLRKLEE 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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