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Conserved domains on  [gi|1176771989|gb|OQY89865|]
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MAG: hypothetical protein B6D38_05575 [Anaerolineae bacterium UTCFX1]

Protein Classification

methyltransferase domain-containing protein( domain architecture ID 1012635)

methyltransferase domain-containing protein similar to Caenorhabditis elegans small RNA 2'-O-methyltransferase that adds a 2'-O-methyl group at the 3'-end of PIWI-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) which are classes of regulatory RNAs that are involved in gene silencing in endogenous RNA interference (RNAi) pathways

EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:0032259
PubMed:  22536158

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiG super family cl34436
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 125-174 8.29e-05

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


The actual alignment was detected with superfamily member COG2227:

Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 41.16  E-value: 8.29e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1176771989 125 TLLEDDIRDLQARGsiAPVDFVLSSSVYEHVDDVEGITRALAALTKPDGL 174
Cdd:COG2227    72 DFVQGDLEDLPLED--GSFDLVICSEVLEHLPDPAALLRELARLLKPGGL 119
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 125-174 8.29e-05

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 41.16  E-value: 8.29e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1176771989 125 TLLEDDIRDLQARGsiAPVDFVLSSSVYEHVDDVEGITRALAALTKPDGL 174
Cdd:COG2227    72 DFVQGDLEDLPLED--GSFDLVICSEVLEHLPDPAALLRELARLLKPGGL 119
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 125-174 8.29e-05

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 41.16  E-value: 8.29e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1176771989 125 TLLEDDIRDLQARGsiAPVDFVLSSSVYEHVDDVEGITRALAALTKPDGL 174
Cdd:COG2227    72 DFVQGDLEDLPLED--GSFDLVICSEVLEHLPDPAALLRELARLLKPGGL 119
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
118-174 3.25e-03

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 36.34  E-value: 3.25e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1176771989 118 RPRPEWMTLLEDDIRDLQARGsiaPVDFVLSSSVYEHVDDVEGITRALAALTKPDGL 174
Cdd:COG4106    42 RARLPNVRFVVADLRDLDPPE---PFDLVVSNAALHWLPDHAALLARLAAALAPGGV 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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