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Conserved domains on  [gi|1176773521|gb|OQY91397|]
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MAG: hypothetical protein B6D38_01975 [Anaerolineae bacterium UTCFX1]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 33-323 8.46e-101

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 298.90  E-value: 8.46e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIGRniRISADVQSSLRAQFGLDKPIfLDQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQL 112
Cdd:COG0601    31 PGDPAAALLGP--RATPEAIAALRAELGLDQPL-LVQYLDWLGGLLRGDLGTSFVYGRPVSDLIAERLPVTLELALLALL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 113 FSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFG-LPTGGIVSPAnigkplhTVLPDLIRH 191
Cdd:COG0601   108 LALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGwLPVSGRVSPW-------EDFLDALRH 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 192 LILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIETV 271
Cdd:COG0601   181 LILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETV 260

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1176773521 272 FSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:COG0601   261 FSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 33-323 8.46e-101

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 298.90  E-value: 8.46e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIGRniRISADVQSSLRAQFGLDKPIfLDQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQL 112
Cdd:COG0601    31 PGDPAAALLGP--RATPEAIAALRAELGLDQPL-LVQYLDWLGGLLRGDLGTSFVYGRPVSDLIAERLPVTLELALLALL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 113 FSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFG-LPTGGIVSPAnigkplhTVLPDLIRH 191
Cdd:COG0601   108 LALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGwLPVSGRVSPW-------EDFLDALRH 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 192 LILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIETV 271
Cdd:COG0601   181 LILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETV 260

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1176773521 272 FSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:COG0601   261 FSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
33-323 7.44e-54

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 179.62  E-value: 7.44e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIGRNiRISADVQSSLRAQFGLDKPIFlDQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQL 112
Cdd:PRK10914   31 PGDPVMIMAGER-GISPERHAQLLAELGLDKPMW-QQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKATLELGVCAMI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 113 FSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFGL-PTGGIVSPA---NIGKPLHTVL--- 185
Cdd:PRK10914  109 FAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLtPVSGRVSDMvflDDSNPLTGFMlid 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 186 ----------PDLIRHLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIA 255
Cdd:PRK10914  189 taiwgedgnfIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIG 268

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1176773521 256 LNLGFTVSGAIYIETVFSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:PRK10914  269 LQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIR 336
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 33-323 1.56e-42

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 149.14  E-value: 1.56e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIG-RNIRISADVQSSLRAQFGLDKPIFLdQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQ 111
Cdd:TIGR02789  31 PSDPAEDYLRlSHIPPTDEAIADMRHSLGLDQPLYV-QYFHWLWNALHLDFGISYISDRPVLDEIARSLPATLELAGFAL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 112 LFSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFG-LPTGGIVSpanigkplhtvlpdlIR 190
Cdd:TIGR02789 110 VIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGVSIPNFWLAFLLVWGFSVYLNlLPTNGAGT---------------WQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 191 HLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIET 270
Cdd:TIGR02789 175 HLVLPAVTLALMSVSIYARLLRASMLDNMQERYVTYARVRGIKERWVIRRHILRNAILPMITALGMHIGELLGGTFVIEN 254

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1176773521 271 VFSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:TIGR02789 255 IFSWPGVGRYAISAIFNRDYPVIQCYTLLMGLLFVFCNLIVDLFQALLDPRIR 307
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 118-323 5.93e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.61  E-value: 5.93e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 118 GVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGsawfglptggivspanigkplhtvLPDLIRHLILPTL 197
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------ILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 198 TFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIETVFSYDGL 277
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1176773521 278 GNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:pfam00528 137 GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 100-313 7.10e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 71.93  E-value: 7.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 100 LWNTLLLIGLGQLFSIIFGVMLGLLAGWKRKtPFDIGALTFSLIAWATPTFWLGIILLVsgsaWFGLPTGGivspanigk 179
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVL----LFGVLLGW--------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 180 plhtvlpDLIRHLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLG 259
Cdd:cd06261    67 -------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFA 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1176773521 260 FTVSGAIYIETVFSYDGLGNLVQTALVKQdypLLQGAFLLLAVSVIAANMLADF 313
Cdd:cd06261   140 RALGEFALVSFLGGGEAPGPGTGLLLIFA---ILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 33-323 8.46e-101

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 298.90  E-value: 8.46e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIGRniRISADVQSSLRAQFGLDKPIfLDQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQL 112
Cdd:COG0601    31 PGDPAAALLGP--RATPEAIAALRAELGLDQPL-LVQYLDWLGGLLRGDLGTSFVYGRPVSDLIAERLPVTLELALLALL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 113 FSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFG-LPTGGIVSPAnigkplhTVLPDLIRH 191
Cdd:COG0601   108 LALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGwLPVSGRVSPW-------EDFLDALRH 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 192 LILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIETV 271
Cdd:COG0601   181 LILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETV 260

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1176773521 272 FSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:COG0601   261 FSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
33-323 7.44e-54

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 179.62  E-value: 7.44e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIGRNiRISADVQSSLRAQFGLDKPIFlDQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQL 112
Cdd:PRK10914   31 PGDPVMIMAGER-GISPERHAQLLAELGLDKPMW-QQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKATLELGVCAMI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 113 FSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFGL-PTGGIVSPA---NIGKPLHTVL--- 185
Cdd:PRK10914  109 FAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLtPVSGRVSDMvflDDSNPLTGFMlid 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 186 ----------PDLIRHLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIA 255
Cdd:PRK10914  189 taiwgedgnfIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIG 268

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1176773521 256 LNLGFTVSGAIYIETVFSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:PRK10914  269 LQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIR 336
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 33-323 7.91e-50

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 167.97  E-value: 7.91e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIGRNIriSADVQSSLRAQFGLDKPIfLDQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQL 112
Cdd:PRK15081   31 PGDPARLAAGPEA--DAQVVALVRQQLGLDQPL-PHQFWHYISNALQGDFGTSMVSRRPVSEEIASRFMPTLWLTITSMV 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 113 FSIIFGVMLGLLAG-WKRKTPFDIGaLTFSLIAWATPTFWLGIILLVSGSAWFG-LPTGGivspanigkplhtvlPDLIR 190
Cdd:PRK15081  108 WAVIFGMAIGIASAvWRNRWPDRLG-MTLAVSGISFPAFALGMLLMQVFSVELGwLPTVG---------------ADSWQ 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 191 HLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIET 270
Cdd:PRK15081  172 HYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEK 251

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1176773521 271 VFSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:PRK15081  252 VFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 33-323 1.56e-42

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 149.14  E-value: 1.56e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIG-RNIRISADVQSSLRAQFGLDKPIFLdQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQ 111
Cdd:TIGR02789  31 PSDPAEDYLRlSHIPPTDEAIADMRHSLGLDQPLYV-QYFHWLWNALHLDFGISYISDRPVLDEIARSLPATLELAGFAL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 112 LFSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFG-LPTGGIVSpanigkplhtvlpdlIR 190
Cdd:TIGR02789 110 VIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGVSIPNFWLAFLLVWGFSVYLNlLPTNGAGT---------------WQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 191 HLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIET 270
Cdd:TIGR02789 175 HLVLPAVTLALMSVSIYARLLRASMLDNMQERYVTYARVRGIKERWVIRRHILRNAILPMITALGMHIGELLGGTFVIEN 254

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1176773521 271 VFSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:TIGR02789 255 IFSWPGVGRYAISAIFNRDYPVIQCYTLLMGLLFVFCNLIVDLFQALLDPRIR 307
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 33-323 1.02e-36

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 134.05  E-value: 1.02e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  33 PGDPVRAVIG-RNIRISADVQSSLRAQFGLDKPIFLdQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQ 111
Cdd:PRK10352   31 TGDPALDYLRlSNLPPTPEMLASTRTMLGLDQPLYV-QYGTWLWKALHLDFGISFATQRPVLDDLLNFLPATLELAGAAL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 112 LFSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGSAWFG-LPTGGIVSpanigkplhtvlpdlIR 190
Cdd:PRK10352  110 VLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYLQwLPAMGYGG---------------WQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 191 HLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIET 270
Cdd:PRK10352  175 HIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMHIGELIGGTMIIEN 254

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1176773521 271 VFSYDGLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:PRK10352  255 IFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIR 307
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 54-322 4.06e-36

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 133.39  E-value: 4.06e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  54 SLRAQFGLDKPIfLDQFVDTLGQWARGNLGVSWSQRRPVSEILISK--------LWNTLLLIglgqLFSIIFGVMLGLLA 125
Cdd:COG4174    85 ELEKQYGFDKPA-HERFLLMLKNYLRFDFGESYFRDISVIDLILEKlpvsislgLWSTLLTY----LISIPLGIRKAVRD 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 126 GwkrkTPFDIGALTFSLIAWATPTFWLGIILLV---SGSAWFGLPTGGIVSPANIGKPLHTVLPDLIRHLILPTLTFTIL 202
Cdd:COG4174   160 G----SRFDVWTSTVIIVGYAIPGFLFAILLIVlfaGGSYFDWFPLRGLTSDNWDQLSWWGKILDYLWHLTLPVTAMVIG 235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 203 YLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVT-IIALNLGFTVSGAIYIETVFSYDGLGNLV 281
Cdd:COG4174   236 GFATLTLLTKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIAgFPAAFIGAFFTGSLLIETIFSLDGLGLLG 315

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1176773521 282 QTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRV 322
Cdd:COG4174   316 FEAVVNRDYPVVFGTLYIFTLIGLVLKLISDLTYVLVDPRI 356
oppB PRK09471
oligopeptide ABC transporter permease OppB;
50-323 2.44e-31

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 119.40  E-value: 2.44e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  50 DVQSSLRAQFGLDKPIFlDQFVDTLGQWARGNLGVSWSQRRPVSEILISKLWNTLLLIGLGQ-LFSIIFGVMLGLLAGWK 128
Cdd:PRK09471   44 EVMANIEAKYHLNDPIM-TQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGAAAfFLAVILGVSAGVIAALK 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 129 RKTPFDIGALTFSLIAWATPTFWLGIIL-LVSGSAWFGLPTGGivspANIGKPlhtvlpdliRHLILPTLTFTILYLGEY 207
Cdd:PRK09471  123 QNTKWDYTVMGFAMTGVVIPSFVVAPLLvLIFAITLHWLPGGG----WNGGAL---------KFMILPMVALSLAYIASI 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 208 MLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIETVFSYDGLGNLVQTALVK 287
Cdd:PRK09471  190 ARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALN 269

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1176773521 288 QDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:PRK09471  270 RDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 50-322 5.18e-30

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 117.15  E-value: 5.18e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  50 DVQSSLRAQFGLDKPIFlDQFVDTLGQWARGNLGVSW----------SQRRPVSEILisKLWNTLLLIglgqLFSIIFGV 119
Cdd:PRK15133   84 EVIAEITHRYGFDKPLH-ERYFKMLWDYIRFDFGDSLfrsasvltliKDSLPVSITL--GLWSTLIIY----LVSIPLGI 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 120 MLGLLAGwkrkTPFDIGALTFSLIAWATPTFWLGIILLV--SGSAWFGL-PTGGIVSPANIGKPLHTVLPDLIRHLILPT 196
Cdd:PRK15133  157 RKAVRNG----SRFDVWSSAFIIIGYAIPAFLFAILLIVffAGGSYFDLfPLRGLVSANFDSLPWYQKITDYLWHITLPV 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 197 LTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVT-IIALNLGFTVSGAIYIETVFSYD 275
Cdd:PRK15133  233 LATVIGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAgFPATFISMFFTGSLLIEVMFSLN 312

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1176773521 276 GLGNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRV 322
Cdd:PRK15133  313 GLGLLGYEATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 118-323 5.93e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.61  E-value: 5.93e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 118 GVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVSGsawfglptggivspanigkplhtvLPDLIRHLILPTL 197
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------ILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 198 TFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIETVFSYDGL 277
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1176773521 278 GNLVQTALVKQDYPLLQGAFLLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:pfam00528 137 GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
PRK15110 PRK15110
peptide ABC transporter permease SapB;
80-320 6.27e-23

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 96.68  E-value: 6.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521  80 GNLGVSWSQRRPVSEILISKLWNTLLLIGLGQLFSIIFGVMLGLLAGWKRKTPFDIGALTFSLIAWATPTFWLGIILLVS 159
Cdd:PRK15110   54 WDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLF 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 160 GSAWFG-LPTGG----------IVSPANIGKPL------HTVLPDLIRHLILPTLTFTILYLGEYMLIMRSSILETLSED 222
Cdd:PRK15110  134 FSLTLGwLPVSGrfdllyevkpVTGFALIDAWLsdspwrDEMIMSAIRHMILPVITLAVAPTTEVIRLMRISTIEVYDQN 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 223 YILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGFTVSGAIYIETVFSYDGLGNLVQTALVKQDYPLLQGAFLLLAV 302
Cdd:PRK15110  214 YVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGS 293

                         250
                  ....*....|....*...
gi 1176773521 303 SVIAANMLADFLYTYLDP 320
Cdd:PRK15110  294 LVIIVNVLSDILGAMANP 311
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 100-313 7.10e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 71.93  E-value: 7.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 100 LWNTLLLIGLGQLFSIIFGVMLGLLAGWKRKtPFDIGALTFSLIAWATPTFWLGIILLVsgsaWFGLPTGGivspanigk 179
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVL----LFGVLLGW--------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 180 plhtvlpDLIRHLILPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLG 259
Cdd:cd06261    67 -------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFA 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1176773521 260 FTVSGAIYIETVFSYDGLGNLVQTALVKQdypLLQGAFLLLAVSVIAANMLADF 313
Cdd:cd06261   140 RALGEFALVSFLGGGEAPGPGTGLLLIFA---ILFPGDLGVAAAVALILLLLSL 190
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 105-319 3.09e-08

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 3.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 105 LLIGLG-QLFSIIFGVMLGLLAGWKRKTpFDIGALTFSLIAWATPTFWLGIILLVSgsawFGLPTGGIVspanigkplht 183
Cdd:COG1173    82 LLVGLLaVLIALVIGVLLGLLAGYFGGW-VDAVLMRLVDVLLAFPSLLLAIALVAV----LGPGLLNVI----------- 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 184 vlpdlirhlilptLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIIALNLGftvs 263
Cdd:COG1173   146 -------------LALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIA---- 208

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1176773521 264 GAIYIETVFSYDGLGNLVQTA----LVKQDYPLLQGAF-------LLLAVSVIAANMLADFLYTYLD 319
Cdd:COG1173   209 SAILAEAGLSFLGLGVQPPTPswgtMLSEGRNYLLTAPwlalfpgLAIVLTVLAFNLLGDGLRDALD 275
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 102-278 2.60e-03

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 39.20  E-value: 2.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 102 NTLLLIGLGQLFSIIFGVMLGLLAGwkrktpfdigalTFSLIAWATPTFWLGIILLVSG---SAWFGLPTGGIVspanig 178
Cdd:PRK15021  131 DVLARILYGTRISVLFGLMLTLCSS------------VMGVLAGALQGYYGGKVDLWGQrfiEVWSGMPTLFLI------ 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 179 kplhTVLPDLIRHLILPTLTFTILYLGEYML-IMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMVTIialn 257
Cdd:PRK15021  193 ----ILLSSVVQPNFWWLLAITVLFGWMSLVgVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTF---- 264

                         170       180
                  ....*....|....*....|.
gi 1176773521 258 LGFTVSGAIYIETVFSYDGLG 278
Cdd:PRK15021  265 LPFILCSSITTLTSLDFLGFG 285
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
105-323 9.73e-03

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 37.07  E-value: 9.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 105 LLIG-LGQLFSIIFGVMLGLLAGWkRKTPFDIGALTFSLIAWATPTFWLGIILLvsgsAWFGlptggivspanigkplht 183
Cdd:PRK10913  102 LLVGcLVVVLSLVMGVILGLIAGY-FGGLVDNIIMRVVDIMLALPSLLLALVLV----AIFG------------------ 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176773521 184 vlPDLIRhlilPTLTFTILYLGEYMLIMRSSILETLSEDYILTARAKGMSNFQVLMRHGLRNAMLPMvtIIALNLGFtvS 263
Cdd:PRK10913  159 --PSIVN----AALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPL--IVQASLGF--S 228

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1176773521 264 GAIYIETVFSYDGLGNLVQT----ALVKQDYPLLQGAF-------LLLAVSVIAANMLADFLYTYLDPRVK 323
Cdd:PRK10913  229 NAILDMAALGFLGMGAQPPTpewgTMLSDVLQFAQSAWwvvtfpgLAILLTVLAFNLMGDGLRDALDPKLK 299
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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