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Conserved domains on  [gi|1232315490|gb|OYV96579|]
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MAG: hypothetical protein B7Z73_00470 [Planctomycetia bacterium 21-64-5]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 708416)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 3-209 4.98e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 4.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490   3 DQNLRLSLLEVLYHEYQVSQQASALVAQVSRAYTVGTLEALAERGSRVTRRAAVLVLGHLAGYNSNHALGRALQDEDRGV 82
Cdd:COG3914     9 LAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  83 ----RLAAEEALRSIWCRAGNDDQRRQLQLILGANTGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIAD 158
Cdd:COG3914    89 qalgRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAA 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1232315490 159 CNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRAN 209
Cdd:COG3914   169 LRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSN 219
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 3-209 4.98e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 4.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490   3 DQNLRLSLLEVLYHEYQVSQQASALVAQVSRAYTVGTLEALAERGSRVTRRAAVLVLGHLAGYNSNHALGRALQDEDRGV 82
Cdd:COG3914     9 LAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  83 ----RLAAEEALRSIWCRAGNDDQRRQLQLILGANTGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIAD 158
Cdd:COG3914    89 qalgRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAA 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1232315490 159 CNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRAN 209
Cdd:COG3914   169 LRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSN 219
TPR_1 pfam00515
Tetratricopeptide repeat;
136-169 2.27e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.79  E-value: 2.27e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1232315490 136 AEAWNQRAIAWYGLGNYAESIADCNQALEINPYH 169
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 106-202 2.33e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 2.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 106 LQLILGANTGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGR 185
Cdd:TIGR02917 435 LLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGN 514

                          90
                  ....*....|....*..
gi 1232315490 186 PRLALESFRRALALNPN 202
Cdd:TIGR02917 515 PDDAIQRFEKVLTIDPK 531
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 136-169 4.51e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.05  E-value: 4.51e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1232315490  136 AEAWNQRAIAWYGLGNYAESIADCNQALEINPYH 169
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 121-198 2.04e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 44.39  E-value: 2.04e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1232315490 121 AIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPyhfgaasGIGQCYLQSGRPRLALESFRRALA 198
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDP-------SLAKAYLRKGTACMKLEEYQTAKA 91
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 141-202 1.53e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.85  E-value: 1.53e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1232315490 141 QRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPN 202
Cdd:cd24142     5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 3-209 4.98e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 4.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490   3 DQNLRLSLLEVLYHEYQVSQQASALVAQVSRAYTVGTLEALAERGSRVTRRAAVLVLGHLAGYNSNHALGRALQDEDRGV 82
Cdd:COG3914     9 LAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  83 ----RLAAEEALRSIWCRAGNDDQRRQLQLILGANTGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIAD 158
Cdd:COG3914    89 qalgRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAA 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1232315490 159 CNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRAN 209
Cdd:COG3914   169 LRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSN 219
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 53-219 5.12e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 5.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  53 RAAVLVLGHLAGYNSNHALGRALQDEDRGVRLAAEEALRSIWCRAGNDDQRRQLQLILGantgrRYHEAIARTTSLIHEA 132
Cdd:COG3914    34 AAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALG-----RYEEALALYRRALALN 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 133 PDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRANVAA 212
Cdd:COG3914   109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGN 188


                  ....*..
gi 1232315490 213 LERTLGK 219
Cdd:COG3914   189 ALQDLGR 195
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
117-202 9.20e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 67.63  E-value: 9.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG4785    88 DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKA 167


                  ....*.
gi 1232315490 197 LALNPN 202
Cdd:COG4785   168 LELDPN 173
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
117-219 1.11e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.72  E-value: 1.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG0457    23 RYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKA 102

                          90       100
                  ....*....|....*....|...
gi 1232315490 197 LALNPNLEGVRANVAALERTLGK 219
Cdd:COG0457   103 LELDPDDAEALYNLGLALLELGR 125
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
117-220 1.78e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.34  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG0457    57 RYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERA 136

                          90       100
                  ....*....|....*....|....
gi 1232315490 197 LALNPNLEGVRANVAALERTLGKK 220
Cdd:COG0457   137 LELDPDDADALYNLGIALEKLGRY 160
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
129-219 1.49e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 64.64  E-value: 1.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 129 IHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRA 208
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90
                  ....*....|.
gi 1232315490 209 NVAALERTLGK 219
Cdd:COG0457    81 NLGLALQALGR 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 117-220 6.72e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.28  E-value: 6.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG4783    19 DYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKA 98

                          90       100
                  ....*....|....*....|....
gi 1232315490 197 LALNPNLEGVRANVAALERTLGKK 220
Cdd:COG4783    99 LKLDPEHPEAYLRLARAYRALGRP 122
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 116-219 1.62e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.36  E-value: 1.62e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 116 RRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRR 195
Cdd:COG2956   124 GDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALER 203

                          90       100
                  ....*....|....*....|....
gi 1232315490 196 ALALNPNLEGVRANVAALERTLGK 219
Cdd:COG2956   204 ALEQDPDYLPALPRLAELYEKLGD 227
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
130-209 1.80e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 55.69  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 130 HEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRAN 209
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 117-215 2.72e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 2.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG4235    32 RYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKL 111

                          90
                  ....*....|....*....
gi 1232315490 197 LALNPNLEGVRANVAALER 215
Cdd:COG4235   112 LALLPADAPARLLEASIAE 130
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 120-219 3.73e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.09  E-value: 3.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 120 EAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALAL 199
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100
                  ....*....|....*....|
gi 1232315490 200 NPNLEGVRANVAALERTLGK 219
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGD 100
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
117-215 4.46e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.01  E-value: 4.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG0457    91 RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKL 170

                          90
                  ....*....|....*....
gi 1232315490 197 LALNPNLEGVRANVAALER 215
Cdd:COG0457   171 EAAALAALLAAALGEAALA 189
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 71-202 5.23e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 5.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  71 LGRALQDEDRGVRLAAEEALRSIWCRAGNDDQRRQLQLILGANTGRrYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLG 150
Cdd:COG4783     8 YALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGD-LDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1232315490 151 NYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPN 202
Cdd:COG4783    87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 54-184 1.05e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 1.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  54 AAVLVLGHLAGYNSNHA-----LGRALQDEDRgvRLAAEEALRSIWcRAGNDDQRRQLQLILGANTGRRYHEAIARTTSL 128
Cdd:COG3914    96 EALALYRRALALNPDNAealfnLGNLLLALGR--LEEALAALRRAL-ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRA 172

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1232315490 129 IHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSG 184
Cdd:COG3914   173 LELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQAC 228
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 83-220 1.21e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 52.27  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  83 RLAAEEALRSIWCRAGNDDQRRQLQLILGANTGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQA 162
Cdd:COG5010     1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1232315490 163 LEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRANVAALERTLGKK 220
Cdd:COG5010    81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
117-203 3.21e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.78  E-value: 3.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIAdCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG3063     7 DLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERA 85


                  ....*..
gi 1232315490 197 LALNPNL 203
Cdd:COG3063    86 LELDPSA 92
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 117-220 7.34e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.65  E-value: 7.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 117 RYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRA 196
Cdd:COG2956   159 DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKA 238

                          90       100
                  ....*....|....*....|....
gi 1232315490 197 LALNPNLEGVRANVAALERTLGKK 220
Cdd:COG2956   239 LELDPSDDLLLALADLLERKEGLE 262
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 100-220 9.36e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 9.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 100 DDQRRQLQLILGAN--TGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIG 177
Cdd:COG2956    72 DPDRAEALLELAQDylKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELA 151

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1232315490 178 QCYLQSGRPRLALESFRRALALNPNLEGVRANVAALERTLGKK 220
Cdd:COG2956   152 ELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDY 194
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 52-201 2.27e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.11  E-value: 2.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  52 RRAAVLVLGHLAGYNSNHALGRALQDEDRGVRLAAEEALRSIWCRAGNDDQRRQLQLILGANTGRRYHEAIARTTSLIHE 131
Cdd:COG5010     4 LEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 132 APDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNP 201
Cdd:COG5010    84 DPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR_1 pfam00515
Tetratricopeptide repeat;
136-169 2.27e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.79  E-value: 2.27e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1232315490 136 AEAWNQRAIAWYGLGNYAESIADCNQALEINPYH 169
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 106-202 2.33e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 2.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 106 LQLILGANTGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGR 185
Cdd:TIGR02917 435 LLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGN 514

                          90
                  ....*....|....*..
gi 1232315490 186 PRLALESFRRALALNPN 202
Cdd:TIGR02917 515 PDDAIQRFEKVLTIDPK 531
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 136-169 4.51e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.05  E-value: 4.51e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1232315490  136 AEAWNQRAIAWYGLGNYAESIADCNQALEINPYH 169
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
145-220 6.29e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 6.29e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1232315490 145 AWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALEsFRRALALNPNLEGVRANVAALERTLGKK 220
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDY 75
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 121-198 2.04e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 44.39  E-value: 2.04e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1232315490 121 AIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPyhfgaasGIGQCYLQSGRPRLALESFRRALA 198
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDP-------SLAKAYLRKGTACMKLEEYQTAKA 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 85-203 2.87e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 2.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  85 AAEEALRSIWCRAGNDDQ-RRQLQLILGANtgRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQAL 163
Cdd:TIGR02917 313 QAYQYLNQILKYAPNSHQaRRLLASIQLRL--GRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKAT 390

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1232315490 164 EINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNL 203
Cdd:TIGR02917 391 ELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPEL 430
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 116-213 6.34e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 6.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 116 RRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRR 195
Cdd:COG2956    22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                          90
                  ....*....|....*...
gi 1232315490 196 ALALNPNLEGVRANVAAL 213
Cdd:COG2956   102 LLELDPDDAEALRLLAEI 119
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 116-215 6.36e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 6.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 116 RRYHEAIARTTSLIHEAPD---FAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAAS---GIGQCYLQSGRPRLA 189
Cdd:COG1729     7 GDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDallKLGLSYLELGDYDKA 86

                          90       100
                  ....*....|....*....|....*.
gi 1232315490 190 LESFRRALALNPNLEGVRANVAALER 215
Cdd:COG1729    87 RATLEELIKKYPDSEAAKEARARLAR 112
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 141-202 1.53e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.85  E-value: 1.53e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1232315490 141 QRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPN 202
Cdd:cd24142     5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 101-219 1.57e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 1.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 101 DQRRQLQLILGANTGRRYHEAIARTTSLIHEAPDFAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAAsgigqcY 180
Cdd:COG3914    15 AALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALL------L 88

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1232315490 181 LQSGRPRLALESFRRALALNPNLEGVRANVAALERTLGK 219
Cdd:COG3914    89 QALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGR 127
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 136-167 3.51e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.73  E-value: 3.51e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1232315490 136 AEAWNQRAIAWYGLGNYAESIADCNQALEINP 167
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_12 pfam13424
Tetratricopeptide repeat;
134-199 5.17e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 5.17e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1232315490 134 DFAEAWNQRAIAWYGLGNYAESIADCNQALEI-----NPYHFGAA---SGIGQCYLQSGRPRLALESFRRALAL 199
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIarrllGPDHPLTAttlLNLGRLYLELGRYEEALELLERALAL 74
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 136-202 6.21e-04

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 39.63  E-value: 6.21e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1232315490 136 AEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPN 202
Cdd:TIGR02521  31 AKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPN 97
TPR_1 pfam00515
Tetratricopeptide repeat;
175-202 6.41e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.24  E-value: 6.41e-04
                          10        20
                  ....*....|....*....|....*...
gi 1232315490 175 GIGQCYLQSGRPRLALESFRRALALNPN 202
Cdd:pfam00515   6 NLGNAYFKLGKYDEALEYYEKALELNPN 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 115-220 7.27e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 7.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 115 GRRYHEAIARTTSLIHEAPDFAEAWNQraIAW-YGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESF 193
Cdd:TIGR02917 783 QKDYDKAIKHYQTVVKKAPDNAVVLNN--LAWlYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLL 860

                          90       100
                  ....*....|....*....|....*..
gi 1232315490 194 RRALALNPNLEGVRANVAALERTLGKK 220
Cdd:TIGR02917 861 RKAVNIAPEAAAIRYHLALALLATGRK 887
HEAT COG1413
HEAT repeat [General function prediction only];
10-93 9.24e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.07  E-value: 9.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490  10 LLEVLYHE-YQVSQQASALVAQVSRAYTVGTLEALAERGSRVTRRAAVLVLGHLAGYNSNHALGRALQDEDRGVRLAAEE 88
Cdd:COG1413    52 LLEALKDPdPEVRAAAAEALGRIGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAAR 131


                  ....*
gi 1232315490  89 ALRSI 93
Cdd:COG1413   132 ALGRL 136
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 141-202 1.00e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 39.68  E-value: 1.00e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1232315490  141 QRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPN 202
Cdd:PRK11447   274 AQGLAAVDSGQGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPH 335
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 176-202 1.99e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 1.99e-03
                           10        20
                   ....*....|....*....|....*..
gi 1232315490  176 IGQCYLQSGRPRLALESFRRALALNPN 202
Cdd:smart00028   7 LGNAYLKLGDYDEALEYYEKALELDPN 33
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 40-93 3.78e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 35.39  E-value: 3.78e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1232315490  40 LEALAERGSRVTRRAAVLVLGHLAGYNSNHALGRALQDEDRGVRLAAEEALRSI 93
Cdd:pfam13646   5 LQALLRDPDPEVRAAAIRALGRIGDPEAVPALLELLKDEDPAVRRAAAEALGKI 58
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 135-219 4.17e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.40  E-value: 4.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232315490 135 FAEAWNQRAIAWYGLGNYAESIADCNQALEINPYHFGAASGIGQCYLQSGRPRLALESFRRALALNPNLEGVRANVAALE 214
Cdd:COG2956     7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86


                  ....*
gi 1232315490 215 RTLGK 219
Cdd:COG2956    87 LKAGL 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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