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Conserved domains on  [gi|1232718602|gb|OYZ46921|]
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MAG: AAA family ATPase [Novosphingobium sp. 16-62-11]

Protein Classification

ATP-binding protein( domain architecture ID 17609121)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain; similar to the ATPase subunit of IS21, IstB, that assembles into a clamshell-shaped decamer that sandwiches DNA to facilitate efficient transposition

CATH:  3.40.50.300
Gene Ontology:  GO:0005524

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 14-245 7.23e-111

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


:

Pssm-ID: 439516  Cd Length: 232  Bit Score: 318.65  E-value: 7.23e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  14 LKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKMQVLE 93
Cdd:NF038214    1 LRQLKLPGMARALEELAEQAAREELSFEEFLALLLEAELAERENRRIERRLKRARFPAAKTLEDFDFTAAPGLDKAQIRE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  94 MARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDEL 173
Cdd:NF038214   81 LATLDFIERAENVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDEL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1232718602 174 GFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAH 245
Cdd:NF038214  161 GYLPFSREGANLLFELIADRYERGSTIITSNLPFSEWGEVFGDPTLAAAILDRLVHHAHILELKGESYRLKE 232
 
Name Accession Description Interval E-value
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 14-245 7.23e-111

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 318.65  E-value: 7.23e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  14 LKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKMQVLE 93
Cdd:NF038214    1 LRQLKLPGMARALEELAEQAAREELSFEEFLALLLEAELAERENRRIERRLKRARFPAAKTLEDFDFTAAPGLDKAQIRE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  94 MARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDEL 173
Cdd:NF038214   81 LATLDFIERAENVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDEL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1232718602 174 GFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAH 245
Cdd:NF038214  161 GYLPFSREGANLLFELIADRYERGSTIITSNLPFSEWGEVFGDPTLAAAILDRLVHHAHILELKGESYRLKE 232
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
10-246 3.26e-106

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 307.09  E-value: 3.26e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  10 LAHHLKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKM 89
Cdd:COG1484     6 LKELLKALKLPGMAEALDELLAQAACDELSYEEFLALLLEAEVAEREQRRIERRLKAARFPAAKTLEDFDFDAQPGLDRR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  90 QVLEMARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLI 169
Cdd:COG1484    86 QILELATLDFIERGENLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLI 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1232718602 170 IDELGFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAHS 246
Cdd:COG1484   166 LDELGYLPLDAEGAELLFELISDRYERRSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLKEA 242
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 14-247 9.82e-74

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 224.63  E-value: 9.82e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  14 LKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKMQVLE 93
Cdd:pfam01695   3 LKQLKLPGMAEAWEELSQQAASTSLSYEEFLEHLLEEELAWRDTRRLERLLRMAKLPPHKTLEDFDFTFAPGLDQRIVAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  94 MARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDEL 173
Cdd:pfam01695  83 LASLSFIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEW 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1232718602 174 GFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAHSR 247
Cdd:pfam01695 163 GYLPLDQAEANLLFQVISKRYEHRSIILTSNLPFGEWGQVFGDAVLATAILDRLLHHCHIVPIKGESYRLKTKS 236
PRK06526 PRK06526
transposase; Provisional
 10-243 1.91e-71

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 219.35  E-value: 1.91e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  10 LAHHLKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKM 89
Cdd:PRK06526    5 LAYLTRALKAPTLAGAVERLAERARAESWSHEEFLAACLQREVAARESHGGEGRIRAARFPARKSLEEFDFDHQRSLKRD 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  90 QVLEMARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLI 169
Cdd:PRK06526   85 TIAHLGTLDFVTGKENVVFLGPPGTGKTHLAIGLGIRACQAGHRVLFATAAQWVARLAAAHHAGRLQAELVKLGRYPLLI 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1232718602 170 IDELGFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRL 243
Cdd:PRK06526  165 VDEVGYIPFEPEAANLFFQLVSSRYERASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHHAEVISLKGDSYRL 238
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 99-233 9.42e-11

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 58.70  E-value: 9.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  99 WIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDER----RLLRFQKQMAGYKLLIIDELG 174
Cdd:cd00009    15 ELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGhflvRLLFELAEKAKPGVLFIDEID 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1232718602 175 FVP--LSKTGAELLFELISQRYERGSTFI--TSNLPFDewtetfgsERLTGALLDRLTHHVSI 233
Cdd:cd00009    95 SLSrgAQNALLRVLETLNDLRIDRENVRVigATNRPLL--------GDLDRALYDRLDIRIVI 149
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 102-234 8.69e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 35.81  E-value: 8.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  102 RRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAG---------------YK 166
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGelrlrlalalarklkPD 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1232718602  167 LLIIDELGFVPLSKTGAELLFE------LISQRYERGSTFITSNLPFDEwtetfgSERLTGALLDRLTHHVSIL 234
Cdd:smart00382  81 VLILDEITSLLDAEQEALLLLLeelrllLLLKSEKNLTVILTTNDEKDL------GPALLRRRFDRRIVLLLIL 148
 
Name Accession Description Interval E-value
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 14-245 7.23e-111

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 318.65  E-value: 7.23e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  14 LKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKMQVLE 93
Cdd:NF038214    1 LRQLKLPGMARALEELAEQAAREELSFEEFLALLLEAELAERENRRIERRLKRARFPAAKTLEDFDFTAAPGLDKAQIRE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  94 MARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDEL 173
Cdd:NF038214   81 LATLDFIERAENVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDEL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1232718602 174 GFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAH 245
Cdd:NF038214  161 GYLPFSREGANLLFELIADRYERGSTIITSNLPFSEWGEVFGDPTLAAAILDRLVHHAHILELKGESYRLKE 232
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
10-246 3.26e-106

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 307.09  E-value: 3.26e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  10 LAHHLKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKM 89
Cdd:COG1484     6 LKELLKALKLPGMAEALDELLAQAACDELSYEEFLALLLEAEVAEREQRRIERRLKAARFPAAKTLEDFDFDAQPGLDRR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  90 QVLEMARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLI 169
Cdd:COG1484    86 QILELATLDFIERGENLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLI 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1232718602 170 IDELGFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAHS 246
Cdd:COG1484   166 LDELGYLPLDAEGAELLFELISDRYERRSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLKEA 242
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 14-247 9.82e-74

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 224.63  E-value: 9.82e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  14 LKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKMQVLE 93
Cdd:pfam01695   3 LKQLKLPGMAEAWEELSQQAASTSLSYEEFLEHLLEEELAWRDTRRLERLLRMAKLPPHKTLEDFDFTFAPGLDQRIVAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  94 MARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDEL 173
Cdd:pfam01695  83 LASLSFIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEW 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1232718602 174 GFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAHSR 247
Cdd:pfam01695 163 GYLPLDQAEANLLFQVISKRYEHRSIILTSNLPFGEWGQVFGDAVLATAILDRLLHHCHIVPIKGESYRLKTKS 236
PRK06526 PRK06526
transposase; Provisional
 10-243 1.91e-71

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 219.35  E-value: 1.91e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  10 LAHHLKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKM 89
Cdd:PRK06526    5 LAYLTRALKAPTLAGAVERLAERARAESWSHEEFLAACLQREVAARESHGGEGRIRAARFPARKSLEEFDFDHQRSLKRD 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  90 QVLEMARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLI 169
Cdd:PRK06526   85 TIAHLGTLDFVTGKENVVFLGPPGTGKTHLAIGLGIRACQAGHRVLFATAAQWVARLAAAHHAGRLQAELVKLGRYPLLI 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1232718602 170 IDELGFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRL 243
Cdd:PRK06526  165 VDEVGYIPFEPEAANLFFQLVSSRYERASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHHAEVISLKGDSYRL 238
PRK09183 PRK09183
transposase/IS protein; Provisional
 15-247 5.74e-69

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 213.03  E-value: 5.74e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  15 KALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKMQVLEM 94
Cdd:PRK09183   14 GQLQLESLISAAPALAQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  95 ARCEWIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLR-FQKQMAGYKLLIIDEL 173
Cdd:PRK09183   94 RSLSFIERNENIVLLGPSGVGKTHLAIALGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTtLQRGVMAPRLLIIDEI 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1232718602 174 GFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETF-GSERLTGALLDRLTHHVSILEMNGESYRLAHSR 247
Cdd:PRK09183  174 GYLPFSQEEANLFFQVIAKRYEKGSMILTSNLPFGQWDQTFaGDAALTSAMLDRLLHHSHVVQIKGESYRLKQKR 248
PRK08181 PRK08181
transposase; Validated
 14-250 9.83e-59

transposase; Validated


Pssm-ID: 136670 [Multi-domain]  Cd Length: 269  Bit Score: 187.44  E-value: 9.83e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  14 LKALKLPTCLREHHKLARQCAAEGVDHIRFLARLVEMEMIDRERRMVERRIKAARFPAVKSLDSFDFAAIPRLNKMQVLE 93
Cdd:PRK08181   16 LNELRLPTIKTLWPQFAEQADKEGWPAARFLAAIAEHELAERARRRIERHLAEAHLPPGKTLDSFDFEAVPMVSKAQVMA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  94 MARCE-WIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDE 172
Cdd:PRK08181   96 IAAGDsWLAKGANLLLFGPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLQVARRELQLESAIAKLDKFDLLILDD 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1232718602 173 LGFVPLSKTGAELLFELISQRYERGSTFITSNLPFDEWTETFGSERLTGALLDRLTHHVSILEMNGESYRLAHSRARK 250
Cdd:PRK08181  176 LAYVTKDQAETSVLFELISARYERRSILITANQPFGEWNRVFPDPAMTLAAVDRLVHHATIFEMNVESYRRRTALERK 253
PRK08116 PRK08116
hypothetical protein; Validated
 49-252 1.41e-11

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 62.73  E-value: 1.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  49 EMEMIDRERRMVERRIKAARFPAVKS------------LDSFDFAaiPRLNKMQVLEMARCE-WIERRENAIAL---GPS 112
Cdd:PRK08116   46 EREAEEAKEREEENREKQRRIERLKSnslldekfrnstFENFLFD--KGSEKAYKIARKYVKkFEEMKKENVGLllwGSV 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602 113 GTGKTHvalglgLAAC------QKGLSVGFTTAAALVSEMMEA-RDERRLLRFQ--KQMAGYKLLIIDELGFVPLSKTGA 183
Cdd:PRK08116  124 GTGKTY------LAACianeliEKGVPVIFVNFPQLLNRIKSTyKSSGKEDENEiiRSLVNADLLILDDLGAERDTEWAR 197

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1232718602 184 ELLFELISQRYERG-STFITSNLPFDEWTETFGSErltgaLLDRlthhvsILEM------NGESYR--LAHSRARKAK 252
Cdd:PRK08116  198 EKVYNIIDSRYRKGlPTIVTTNLSLEELKNQYGKR-----IYDR------ILEMctpvenEGKSYRkeIAKEKLQRLK 264
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 84-243 1.50e-11

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 63.38  E-value: 1.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  84 PRLNKMQVLEMARCeWIE----RRENAIALGPSGTGKTHvalglgLAAC------QKGLSVGFTTAAALVSEMMEARder 153
Cdd:PRK06835  161 PRKNMEKILEKCKN-FIEnfdkNNENLLFYGNTGTGKTF------LSNCiakellDRGKSVIYRTADELIEILREIR--- 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602 154 rlLRFQKQM-AGYK------LLIIDELGFVPLSKTGAELLFELISQRYERG-STFITSNLPFDEWTETFgSERLTGalld 225
Cdd:PRK06835  231 --FNNDKELeEVYDllincdLLIIDDLGTEKITEFSKSELFNLINKRLLRQkKMIISTNLSLEELLKTY-SERISS---- 303

                         170
                  ....*....|....*...
gi 1232718602 226 RLTHHVSILEMNGESYRL 243
Cdd:PRK06835  304 RLLGNFTLLKFYGEDIRI 321
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 99-233 9.42e-11

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 58.70  E-value: 9.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  99 WIERRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDER----RLLRFQKQMAGYKLLIIDELG 174
Cdd:cd00009    15 ELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGhflvRLLFELAEKAKPGVLFIDEID 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1232718602 175 FVP--LSKTGAELLFELISQRYERGSTFI--TSNLPFDewtetfgsERLTGALLDRLTHHVSI 233
Cdd:cd00009    95 SLSrgAQNALLRVLETLNDLRIDRENVRVigATNRPLL--------GDLDRALYDRLDIRIVI 149
PRK07952 PRK07952
DNA replication protein DnaC; Validated
 77-242 3.99e-07

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 49.77  E-value: 3.99e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  77 SFDFAAIPRLNKMQVLEMARcEWIERRENAIA----LGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARD- 151
Cdd:PRK07952   70 SFENYRVECEGQMNALSKAR-QYVEEFDGNIAsfifSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSn 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602 152 ----ERRLLRfqkQMAGYKLLIIDELGFVPLSKTGAELLFELISQRY-ERGSTFITSNLPFDEWTETFGsERltgaLLDR 226
Cdd:PRK07952  149 setsEEQLLN---DLSNVDLLVIDEIGVQTESRYEKVIINQIVDRRSsSKRPTGMLTNSNMEEMTKLLG-ER----VMDR 220

                         170
                  ....*....|....*..
gi 1232718602 227 LTHHVSI-LEMNGESYR 242
Cdd:PRK07952  221 MRLGNSLwVIFNWDSYR 237
PRK12377 PRK12377
putative replication protein; Provisional
 110-252 4.55e-06

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 46.37  E-value: 4.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602 110 GPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRL-LRFQKQMAGYKLLIIDELGFVPLSKTGAELLFE 188
Cdd:PRK12377  108 GKPGTGKNHLAAAIGNRLLAKGRSVIVVTVPDVMSRLHESYDNGQSgEKFLQELCKVDLLVLDEIGIQRETKNEQVVLNQ 187

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1232718602 189 LISQRYER-GSTFITSNLPFDEWTETFGsERltgaLLDRLThhvsileMNG--------ESYRLAHSRARKAK 252
Cdd:PRK12377  188 IIDRRTASmRSVGMLTNLNHEAMSTLLG-ER----VMDRMT-------MNGgrwvnfnwESWRPNVSHLRIVK 248
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
98-227 9.67e-06

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 45.95  E-value: 9.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  98 EWIERRENAIAL-GPSGTGKTHV--ALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDELG 174
Cdd:COG0593    28 EWPGKAYNPLFLyGGVGLGKTHLlhAIGNEALENNPGARVVYLTAEEFTNDFINAIRNNTIEEFKEKYRSVDVLLIDDIQ 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1232718602 175 FVPLSKTGAELLFELISQRYERGSTFI-TSNLPFDEWTEtfgserltgaLLDRL 227
Cdd:COG0593   108 FLAGKEATQEEFFHTFNALREAGKQIVlTSDRPPKELPG----------LEERL 151
Bac_DnaA pfam00308
Bacterial dnaA protein;
110-212 7.56e-04

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 39.62  E-value: 7.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602 110 GPSGTGKTHV--ALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAGYKLLIIDELGFVPLSKTGAELLF 187
Cdd:pfam00308  41 GGVGLGKTHLlhAIGNYALQNAPNLRVVYLTAEEFLNDFVDAIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFF 120

                          90       100
                  ....*....|....*....|....*.
gi 1232718602 188 ELISQRYERG-STFITSNLPFDEWTE 212
Cdd:pfam00308 121 HTFNALHESGkQIVFSSDRPPKELEE 146
RecD COG0507
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ...
 13-172 1.74e-03

ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];


Pssm-ID: 440273 [Multi-domain]  Cd Length: 514  Bit Score: 39.19  E-value: 1.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  13 HLKALKLPTCLREHHKLARQCAAEG---VDHIRFLARLVEME--MIDRERRMVERRIKAARFPAVksLDSFDFAAIPRLN 87
Cdd:COG0507    49 DLAAARLLGVAEDIEAALAALVESGplvLDGRRYLTRLLEAEqrLARRLRRLARPALDEADVEAA--LAALEPRAGITLS 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  88 KMQ--VLEMArcewIERRENAIALGPSGTGKTHVALGLGLAACQKGLSV---GFTTAAALVseMMEARDER-----RLLR 157
Cdd:COG0507   127 DEQreAVALA----LTTRRVSVLTGGAGTGKTTTLRALLAALEALGLRValaAPTGKAAKR--LSESTGIEartihRLLG 200

                         170       180
                  ....*....|....*....|....*.
gi 1232718602 158 FQKQMAGYK-----------LLIIDE 172
Cdd:COG0507   201 LRPDSGRFRhnrdnpltpadLLVVDE 226
PtaN COG0857
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
107-136 7.24e-03

BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];


Pssm-ID: 440618 [Multi-domain]  Cd Length: 697  Bit Score: 37.50  E-value: 7.24e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1232718602 107 IALGPsGTGKTHVALGLGLAACQKGLSVGF 136
Cdd:COG0857     8 ASTEP-GSGKTSVALGLARALQRKGLRVGY 36
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 102-234 8.69e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 35.81  E-value: 8.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1232718602  102 RRENAIALGPSGTGKTHVALGLGLAACQKGLSVGFTTAAALVSEMMEARDERRLLRFQKQMAG---------------YK 166
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGelrlrlalalarklkPD 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1232718602  167 LLIIDELGFVPLSKTGAELLFE------LISQRYERGSTFITSNLPFDEwtetfgSERLTGALLDRLTHHVSIL 234
Cdd:smart00382  81 VLILDEITSLLDAEQEALLLLLeelrllLLLKSEKNLTVILTTNDEKDL------GPALLRRRFDRRIVLLLIL 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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