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Conserved domains on  [gi|121323|sp|P08151|]
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RecName: Full=Zinc finger protein GLI1; AltName: Full=Glioma-associated oncogene; AltName: Full=Oncogene GLI

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 562-1081 4.93e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     878 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 957
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     958 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 1037
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 121323    1038 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC super family cl24666
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


The actual alignment was detected with superfamily member pfam16159:

Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 121323      237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 297-387 5.15e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 121323    377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 562-1081 4.93e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     878 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 957
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     958 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 1037
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 121323    1038 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 121323      237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 297-387 5.15e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 121323    377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
317-344 2.66e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.66e-05
                           10        20
                   ....*....|....*....|....*...
gi 121323      317 NLKTHLRSHTGEKPYMCEHegCSKAFSN 344
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
196-433 2.31e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    196 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 268
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    269 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 339
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    340 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 398
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 121323    399 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 433
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 562-1081 4.93e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     878 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 957
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     958 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 1037
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 121323    1038 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 121323      237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 297-387 5.15e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 121323    377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
317-344 2.66e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.66e-05
                           10        20
                   ....*....|....*....|....*...
gi 121323      317 NLKTHLRSHTGEKPYMCEHegCSKAFSN 344
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 725-877 3.10e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 48.54  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     725 PPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGP---PTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKAlgGTYS 801
Cdd:PRK10263  339 PVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPviaPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAA--EQPA 416

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 121323     802 QCPRLEHYGQVQVKPEQGCPVGSDSTGLAPcLNAHPSEGPPHPQPLF---SHYPQPSPPQYLQSGPYTQPPPDYLPSEP 877
Cdd:PRK10263  417 QQPYYAPAPEQPAQQPYYAPAPEQPVAGNA-WQAEEQQSTFAPQSTYqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEP 494
zf-H2C2_2 pfam13465
Zinc-finger double domain;
287-314 3.20e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.59  E-value: 3.20e-05
                           10        20
                   ....*....|....*....|....*...
gi 121323      287 MLVVHMRRHTGEKPHKCTFegCRKSYSR 314
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
PHA03247 PHA03247
large tegument protein UL36; Provisional
 511-870 1.02e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     511 PIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPglmpaqhyllr 590
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP----------- 2819

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     591 aryASARGGGTSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPTVA 670
Cdd:PHA03247 2820 ---PAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTE 2896

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     671 GGGQNFD-PYLPTSVYSPQPPSITENAAMDARGLQEEPEvgtsmvgSGLNPYMDFPPTDTLGYGGPEGAAAEPY-GARGP 748
Cdd:PHA03247 2897 SFALPPDqPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-------PPRPQPPLAPTTDPAGAGEPSGAVPQPWlGALVP 2969

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     749 GSLPL------GPGPPTNYGPNPCPQQASYPDPTQETWGE-FPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQgcP 821
Cdd:PHA03247 2970 GRVAVprfrvpQPAPSREAPASSTPPLTGHSLSRVSSWASsLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSD--S 3047

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 121323     822 VGSDSTGLAPclnahpseGPPHPQPLFSHYPQPSPPQY-LQSGPYTQ--PPP 870
Cdd:PHA03247 3048 ERSDLEALDP--------LPPEPHDPFAHEPDPATPEAgARESPSSQfgPPP 3091
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
299-379 3.23e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.69  E-value: 3.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    299 KPHKCtfEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNaSDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSS 378
Cdd:COG5048   32 RPDSC--PNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSR-PLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108


                 .
gi 121323    379 L 379
Cdd:COG5048  109 S 109
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
291-347 4.22e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.30  E-value: 4.22e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 121323    291 HMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 347
Cdd:COG5048   52 HIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108
dnaA PRK14086
chromosomal replication initiator protein DnaA;
763-983 4.86e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 44.05  E-value: 4.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     763 PNPCPQQASYPDPTQETWGEFPSHSglYPGPKALggtysqcPRLEHYGQVQVKPEqgcpvgsdSTGLAPCLNAHPSEGPp 842
Cdd:PRK14086   96 APPPPHARRTSEPELPRPGRRPYEG--YGGPRAD-------DRPPGLPRQDQLPT--------ARPAYPAYQQRPEPGA- 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     843 HPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEP-RPCLDFDSPTHSTGQLKaqlvcnyvQSQQELLWEGGGREDAPAQ 921
Cdd:PRK14086  158 WPRAADDYGWQQQRLGFPPRAPYASPASYAPEQERdREPYDAGRPEYDQRRRD--------YDHPRPDWDRPRRDRTDRP 229

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 121323     922 EPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSgSYPTPSPCH---------ENFVVGA-NRASH 983
Cdd:PRK14086  230 EPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPA-PAPGPGEPTarlnpkytfDTFVIGAsNRFAH 300
PHA03247 PHA03247
large tegument protein UL36; Provisional
 562-1039 1.07e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     562 ASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASsldrigglPMPPWRSRAEYPGYNPNAgvtrrASD 641
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSAR--------PRAPVDDRGDPRGPAPPS-----PLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     642 PAQAA-DRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSgLNP 720
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS-LTS 2697

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     721 YMDFPPtdtlgyggPEGAAAEPYGARGPGsLPLGPGPPTNYGPNPCPQQASYPDPTQETwGEFPSHSGLYPGPKALGGTY 800
Cdd:PHA03247 2698 LADPPP--------PPPTPEPAPHALVSA-TPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPARPPTTAGPP 2767

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     801 SQCPrlehyGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPC 880
Cdd:PHA03247 2768 APAP-----PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     881 LDFDSPTHSTgqlkaqlvCNYVQSQQELLWEGGGREDAPA-QEPSYQSPKFLGGSQVSPSRAKAPVNTYGPgfgPNLPNH 959
Cdd:PHA03247 2843 PGPPPPSLPL--------GGSVAPGGDVRRRPPSRSPAAKpAAPARPPVRRLARPAVSRSTESFALPPDQP---ERPPQP 2911

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     960 KSGSYPTPSPCHENfvvgANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLggGPALYPPPEGQVCNPLDS 1039
Cdd:PHA03247 2912 QAPPPPQPQPQPPP----PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL--VPGRVAVPRFRVPQPAPS 2985
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
520-652 1.93e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323     520 PSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGG 599
Cdd:PRK12323  365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 121323     600 GTSPTAASSLdriggLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPA 652
Cdd:PRK12323  445 GGAPAPAPAP-----AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPA 492
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
275-382 2.27e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.99  E-value: 2.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    275 CSRELRPFKAQYMLVVHMR--RHTGE--KPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAK 350
Cdd:COG5048  292 SKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNEP 371

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 121323    351 HQ----NRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 382
Cdd:COG5048  372 PQslqqYKDLKNDKKSETLSNSCIRNFKRDSNLSLH 407
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
196-433 2.31e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    196 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 268
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    269 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 339
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121323    340 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 398
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 121323    399 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 433
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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