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Conserved domains on  [gi|1277971130|gb|PIV64840|]
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hypothetical protein COS11_00100 [bacterium (Candidatus Ratteibacteria) CG01_land_8_20_14_3_00_40_19]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 4-99 1.87e-08

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 50.01  E-value: 1.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277971130   4 KGFTLLETLVTMVIAFLILGVIYGSYQGVFGTTRESKELFSHYQTANLLLRKMSEEI------ASSFISSGLPFQGEREE 77
Cdd:COG4795     9 RGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLrqagprPDEGGDPEPALSGGGSC 88

                          90       100
                  ....*....|....*....|....*
gi 1277971130  78 LIFFTSKSSAN---SDLSKINYFLR 99
Cdd:COG4795    89 LIDLNRNGWWNplrSELQRVGYRLR 113
T2SSJ super family cl42010
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 104-162 1.39e-05

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


The actual alignment was detected with superfamily member pfam11612:

Pssm-ID: 455355  Cd Length: 137  Bit Score: 42.70  E-value: 1.39e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1277971130 104 EEKILIRR-ETIPFSAVPGRPFSLTPLKGI---SFRYFDGKEWLSQWDSE---TKLPKSVSIELNL 162
Cdd:pfam11612  62 EDGRLERLtWPYLDGAVGQEPQVQVLLDGVeslRLRFLDDGQWQDRWPPAaadQALPRAVEITLEL 127
 
Name Accession Description Interval E-value
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 4-99 1.87e-08

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 50.01  E-value: 1.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277971130   4 KGFTLLETLVTMVIAFLILGVIYGSYQGVFGTTRESKELFSHYQTANLLLRKMSEEI------ASSFISSGLPFQGEREE 77
Cdd:COG4795     9 RGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLrqagprPDEGGDPEPALSGGGSC 88

                          90       100
                  ....*....|....*....|....*
gi 1277971130  78 LIFFTSKSSAN---SDLSKINYFLR 99
Cdd:COG4795    89 LIDLNRNGWWNplrSELQRVGYRLR 113
T2SSJ pfam11612
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 104-162 1.39e-05

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


Pssm-ID: 431959  Cd Length: 137  Bit Score: 42.70  E-value: 1.39e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1277971130 104 EEKILIRR-ETIPFSAVPGRPFSLTPLKGI---SFRYFDGKEWLSQWDSE---TKLPKSVSIELNL 162
Cdd:pfam11612  62 EDGRLERLtWPYLDGAVGQEPQVQVLLDGVeslRLRFLDDGQWQDRWPPAaadQALPRAVEITLEL 127
gspJ TIGR01711
type II secretion system protein J; This model represents GspJ, one of two proteins highly ...
 5-162 1.63e-05

type II secretion system protein J; This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 130772 [Multi-domain]  Cd Length: 192  Bit Score: 43.36  E-value: 1.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277971130   5 GFTLLETLVTMVI-AFLILGViYGSYQGVFGT---TRESKELFSHYQTANLLL----RKMSEEI------ASSFISSGLP 70
Cdd:TIGR01711   2 GFTLLELLVAIAIfASLSLGA-YQVLDSVMQSdeaTRVQEARLRELQRAMGAMerdlTQMVERPvrddgeASEQDLRGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277971130  71 F-QGEREELIFFTS-------KSSANSDLSKINYFLRpDNKEEKILIRRETIPFSAVPGRPFSLTPLKGISFRYFDGKEW 142
Cdd:TIGR01711  81 LsEGSDDQGVEFTRggwrnplGQQPRSRLQRVGWRLS-GETLERRYWLYPDRAQGSKPRIQPVLDGVTALSWRFYDKGNW 159

                         170       180
                  ....*....|....*....|
gi 1277971130 143 LSQWDSETKLPKSVSIELNL 162
Cdd:TIGR01711 160 QGEWPTDNSLPLAVEVTLEL 179
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 3-26 1.23e-03

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 35.04  E-value: 1.23e-03
                          10        20
                  ....*....|....*....|....
gi 1277971130   3 KKGFTLLETLVTMVIAFLILGVIY 26
Cdd:pfam07963   4 QRGFTLIELLVALAILAILLAAAL 27
 
Name Accession Description Interval E-value
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 4-99 1.87e-08

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 50.01  E-value: 1.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277971130   4 KGFTLLETLVTMVIAFLILGVIYGSYQGVFGTTRESKELFSHYQTANLLLRKMSEEI------ASSFISSGLPFQGEREE 77
Cdd:COG4795     9 RGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLrqagprPDEGGDPEPALSGGGSC 88

                          90       100
                  ....*....|....*....|....*
gi 1277971130  78 LIFFTSKSSAN---SDLSKINYFLR 99
Cdd:COG4795    89 LIDLNRNGWWNplrSELQRVGYRLR 113
PilW COG4966
Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];
4-60 3.41e-06

Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];


Pssm-ID: 443992 [Multi-domain]  Cd Length: 158  Bit Score: 44.79  E-value: 3.41e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1277971130   4 KGFTLLETLVTMVIAFLILGVIYGSYQGVFGTTRESKELFSHYQTANLLLRKMSEEI 60
Cdd:COG4966     5 RGFTLVELMVALAIGLIVLAAVLQLFLSSRRSYRTQEALARLQENGRFALDLLSRDL 61
FimT COG4970
Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];
4-49 3.67e-06

Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];


Pssm-ID: 443996 [Multi-domain]  Cd Length: 73  Bit Score: 42.91  E-value: 3.67e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1277971130   4 KGFTLLETLVTMVIAFLILGVIYGSYQGVFGTTR---ESKELFSHYQTA 49
Cdd:COG4970     9 RGFTLIELLVVLAILAILAAIAVPSFSSLIARQRlraAANELAAALRLA 57
PilV COG4967
Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];
4-70 5.23e-06

Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];


Pssm-ID: 443993 [Multi-domain]  Cd Length: 86  Bit Score: 42.66  E-value: 5.23e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1277971130   4 KGFTLLETLVTMVI-AFLILGVIygSYQGVfgTTRESKELfSHYQTANLLLRKMSEEI-ASSFISSGLP 70
Cdd:COG4967    11 RGFTLIEVLVALVIlSIGLLGLA--GLQAA--SLRSSQDA-RQRTQAALLAQDLLERLrANPAAAGSYP 74
T2SSJ pfam11612
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 104-162 1.39e-05

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


Pssm-ID: 431959  Cd Length: 137  Bit Score: 42.70  E-value: 1.39e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1277971130 104 EEKILIRR-ETIPFSAVPGRPFSLTPLKGI---SFRYFDGKEWLSQWDSE---TKLPKSVSIELNL 162
Cdd:pfam11612  62 EDGRLERLtWPYLDGAVGQEPQVQVLLDGVeslRLRFLDDGQWQDRWPPAaadQALPRAVEITLEL 127
gspJ TIGR01711
type II secretion system protein J; This model represents GspJ, one of two proteins highly ...
 5-162 1.63e-05

type II secretion system protein J; This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 130772 [Multi-domain]  Cd Length: 192  Bit Score: 43.36  E-value: 1.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277971130   5 GFTLLETLVTMVI-AFLILGViYGSYQGVFGT---TRESKELFSHYQTANLLL----RKMSEEI------ASSFISSGLP 70
Cdd:TIGR01711   2 GFTLLELLVAIAIfASLSLGA-YQVLDSVMQSdeaTRVQEARLRELQRAMGAMerdlTQMVERPvrddgeASEQDLRGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277971130  71 F-QGEREELIFFTS-------KSSANSDLSKINYFLRpDNKEEKILIRRETIPFSAVPGRPFSLTPLKGISFRYFDGKEW 142
Cdd:TIGR01711  81 LsEGSDDQGVEFTRggwrnplGQQPRSRLQRVGWRLS-GETLERRYWLYPDRAQGSKPRIQPVLDGVTALSWRFYDKGNW 159

                         170       180
                  ....*....|....*....|
gi 1277971130 143 LSQWDSETKLPKSVSIELNL 162
Cdd:TIGR01711 160 QGEWPTDNSLPLAVEVTLEL 179
PulG COG2165
Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, ...
 3-42 1.05e-04

Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 441768 [Multi-domain]  Cd Length: 99  Bit Score: 39.51  E-value: 1.05e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1277971130   3 KKGFTLLETLVTMVIAFLILGVIYGSYQGVFGTTRESKEL 42
Cdd:COG2165    10 QRGFTLIELLVVIAIIGILAALALPALQGARERARRAELR 49
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 3-26 1.23e-03

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 35.04  E-value: 1.23e-03
                          10        20
                  ....*....|....*....|....
gi 1277971130   3 KKGFTLLETLVTMVIAFLILGVIY 26
Cdd:pfam07963   4 QRGFTLIELLVALAILAILLAAAL 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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