|
Name |
Accession |
Description |
Interval |
E-value |
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
1-934 |
0e+00 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 1546.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 1 MLEKGYNPQGIEERWYEYWVSKGYFKPDPDLKGSFYSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGT 80
Cdd:COG0525 2 ELPKTYDPKEVEAKWYQYWEENGYFKADPDSDKEPFTIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWQPGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 81 DHAGIATQNVVEKQLASTGLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRL 160
Cdd:COG0525 82 DHAGIATQAVVERQLAEEGKSRHDLGREKFLERVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFVRL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 161 YEEGLIYRDNRLINWCPRCNTALSDLEVEYEELEGKLTYIKYPLTppipplarGGDnkrGYITVATTRPETMLGDTAVAV 240
Cdd:COG0525 162 YEKGLIYRGKRLVNWDPKLKTALSDLEVEHEEVKGHLWHIRYPLA--------DGS---GYIVVATTRPETMLGDTAVAV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 241 NPEDSRYQKFIGKTINLPLTDRKILIISDHAVDPSFGTGAVKVTPAHDFNDEAIAKKQipPLEFITVIGADGLMTVNAGn 320
Cdd:COG0525 231 HPEDERYKHLIGKTVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKRH--NLPMINILDEDGTINENAG- 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 321 RYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKEGKINIIPKTWE 400
Cdd:COG0525 308 KYRGLDRFEARKAIVADLEELGLLVKVEPHKHSVGHSDRSGTVIEPYLSDQWFVKMKPLAKPAIEAVEDGEIKFVPERWE 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 401 NTYFAWMEDIKDWCISRQIWWGHRIPVWYCQkmqnakckmQNGVIVSRDVPQVCPYCSSEELIQDEDVLDTWFSSALWPF 480
Cdd:COG0525 388 KTYFHWMENIRDWCISRQLWWGHRIPAWYCP---------DGEVYVARTEPEACAKAGSVNLTQDEDVLDTWFSSALWPF 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 481 STLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMID 560
Cdd:COG0525 459 STLGWPEKTEDLKYFYPTSVLVTGFDIIFFWVARMIMMGLHFTGEVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLID 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 561 RYGTDAFRFTLAAFTAQGRDIKFSEKRVEGYRHFVNKLWNAARFIMMNTNPPTPPLEkggkggfekegverITHTPHDLA 640
Cdd:COG0525 539 KYGADALRFTLAALASPGRDIKFDEERVEGYRNFANKLWNASRFVLMNLEGFDPGLD--------------PDPEELSLA 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 641 SKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEINpptqpslsrgegkGGDgnseprtPNSQT 720
Cdd:COG0525 605 DRWILSRLNKTIAEVTEALEKYRFDEAAQALYDFVWNEFCDWYLELAKPRLY-------------GGD-------EAAKR 664
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 721 GVRWCLLHTLDTSLRLLHPFMPFVTEEIWQTIKIQHSAikESIMVSDYPKSLP--RDYQAEEDMSYIIEAVMGIRTIRGE 798
Cdd:COG0525 665 ETRATLVYVLEQILRLLHPFMPFITEEIWQKLPPRKEG--ESIMLAPWPEADEelIDEEAEAEFEWLKEVISAIRNIRAE 742
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 799 LNISPSLKLNVSIKTFSQMAEKILKENVQYLKNLAKAGEIKIGmNIEKPECSATSVKSSMEIYVPLKGVLNITAEVDRLK 878
Cdd:COG0525 743 MNIPPSKKLPLLLKGADEADRARLEENAAYIKRLARLEEITIL-VDEKPEGAASAVVGGAEVFLPLEGLIDVEAERARLE 821
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*.
gi 1278345029 879 KEEAKVDVSIVSLNRKLFNEDFLQRAPREIIDKEKAKYEELIIIKKRILESIKMLK 934
Cdd:COG0525 822 KELAKLEKEIARVEKKLSNEGFVAKAPAEVVEKEREKLAEAEAKLEKLEEQLARLK 877
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
1-935 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 1486.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 1 MLEKGYNPQGIEERWYEYWVSKGYFKPDPDLKGSFySLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGT 80
Cdd:PRK05729 4 ELPKTYDPKEVEAKWYQKWEEKGYFKPDDNSKKPF-SIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWLPGT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 81 DHAGIATQNVVEKQLASTGLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRL 160
Cdd:PRK05729 83 DHAGIATQMVVERQLAAEGKSRHDLGREKFLEKVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFVRL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 161 YEEGLIYRDNRLINWCPRCNTALSDLEVEYEELEGKLTYIKYPLTppipplarggdNKRGYITVATTRPETMLGDTAVAV 240
Cdd:PRK05729 163 YEKGLIYRGKRLVNWDPKLQTALSDLEVEYKEVKGKLWHIRYPLA-----------DGSDYLVVATTRPETMLGDTAVAV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 241 NPEDSRYQKFIGKTINLPLTDRKILIISDHAVDPSFGTGAVKVTPAHDFNDEAIAKKQipPLEFITVIGADGLMTVNAGn 320
Cdd:PRK05729 232 NPEDERYKHLIGKTVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKRH--NLPMINIMDEDGTINENPG- 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 321 RYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKEGKINIIPKTWE 400
Cdd:PRK05729 309 EYQGLDRFEARKAIVADLEELGLLVKIEPHTHSVGHSDRSGVVIEPYLSDQWFVKMKPLAKPALEAVENGEIKFVPERWE 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 401 NTYFAWMEDIKDWCISRQIWWGHRIPVWYCQkmqnakckmQNGVIVSRDVPQVCPYCsseELIQDEDVLDTWFSSALWPF 480
Cdd:PRK05729 389 KTYFHWMENIQDWCISRQLWWGHRIPAWYDE---------DGEVYVGREEPEAREKA---LLTQDEDVLDTWFSSALWPF 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 481 STLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMID 560
Cdd:PRK05729 457 STLGWPEKTEDLKRFYPTSVLVTGFDIIFFWVARMIMMGLHFTGQVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLID 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 561 RYGTDAFRFTLAAFTAQGRDIKFSEKRVEGYRHFVNKLWNAARFIMMNTNPPTPPlekggkggfekegvERITHTPHDLA 640
Cdd:PRK05729 537 KYGADALRFTLAALASPGRDIRFDEERVEGYRNFANKLWNASRFVLMNLEGADVG--------------ELPDPEELSLA 602
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 641 SKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEINpptqpslsrgegkggdgnseprtPNSQT 720
Cdd:PRK05729 603 DRWILSRLNRTVAEVTEALDKYRFDEAARALYEFIWNEFCDWYLELAKPVLQ-----------------------EAAKR 659
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 721 GVRWCLLHTLDTSLRLLHPFMPFVTEEIWQtiKIQHSAIKESIMVSDYPKSLP-RDYQAEEDMSYIIEAVMGIRTIRGEL 799
Cdd:PRK05729 660 ATRATLAYVLEQILRLLHPFMPFITEELWQ--KLAPLGIEESIMLAPWPEADEaIDEAAEAEFEWLKELITAIRNIRAEM 737
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 800 NISPSLKLNVSIKTFSQMAEKILKENVQYLKNLAKAGEIKIGMNIEK-PECSATSVKSSMEIYVPLKGVLNITAEVDRLK 878
Cdd:PRK05729 738 NIPPSKKLPLLLKGADAEDRARLEANEAYIKRLARLESLEILADDEEaPEGAASAVVGGAELFLPLEGLIDVEAELARLE 817
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*..
gi 1278345029 879 KEEAKVDVSIVSLNRKLFNEDFLQRAPREIIDKEKAKYEELIIIKKRILESIKMLKD 935
Cdd:PRK05729 818 KELAKLEKEIERVEKKLSNEGFVAKAPEEVVEKEREKLAEYEEKLAKLKERLARLKA 874
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
2-917 |
0e+00 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 1139.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 2 LEKGYNPQGIEERWYEYWVSKGYFKPDPDLKGSFYSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTD 81
Cdd:TIGR00422 1 MPKDYDPHEVEKKWYKKWEKSGFFKPDGNSNKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGTD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 82 HAGIATQNVVEKQLASTGLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLY 161
Cdd:TIGR00422 81 HAGIATQVKVEKKLGAEGKTKHDLGREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAFVRLY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 162 EEGLIYRDNRLINWCPRCNTALSDLEVEYEELEGKLTYIKYPLTppipplarggDNKRGYITVATTRPETMLGDTAVAVN 241
Cdd:TIGR00422 161 EKGLIYRGEYLVNWDPKLNTAISDIEVEYKEVKGKLYYIRYPLA----------NGSKDYLVVATTRPETMFGDTAVAVH 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 242 PEDSRYQKFIGKTINLPLTDRKILIISDHAVDPSFGTGAVKVTPAHDFNDEAIAKKQipPLEFITVIGADGLMTVNAGnR 321
Cdd:TIGR00422 231 PEDERYKHLIGKKVILPLTGRKIPIIADEYVDMEFGTGAVKVTPAHDFNDYEWGKRH--NLEFINILDEDGLLNENAG-K 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 322 YAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKEGKINIIPKTWEN 401
Cdd:TIGR00422 308 YQGLTRFEARKKIVEDLKEEGLLVKIEPHTHNVGTCWRSGTVVEPLLSKQWFVKVEKLADKALEAAEEGEIKFVPKRMEK 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 402 TYFAWMEDIKDWCISRQIWWGHRIPVWYCQKMQNakckmqngVIVSRDVPQV---CPYCSSEELIQDEDVLDTWFSSALW 478
Cdd:TIGR00422 388 RYLNWLRNIKDWCISRQLIWGHRIPVWYCKECGE--------VYVAKEEPLPddkTNTGPSVELEQDTDVLDTWFSSSLW 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 479 PFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIM 558
Cdd:TIGR00422 460 PFSTLGWPDETKDLKKFYPTDLLVTGYDIIFFWVARMIFRSLALTGQVPFKEVYIHGLVRDEQGRKMSKSLGNVIDPLDV 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 559 IDRYGTDAFRFTLAAFTAQGRDIKFSEKRVEGYRHFVNKLWNAARFIMMNTnpptpplekggkggFEKEGVERiTHTPHD 638
Cdd:TIGR00422 540 IEKYGADALRFTLASLVTPGDDINFDWKRVESARNFLNKLWNASRFVLMNL--------------SDDLELSG-GEEKLS 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 639 LASKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEINpptqpslsrgegkggdgnsePRTPNS 718
Cdd:TIGR00422 605 LADRWILSKLNRTIKEVRKALDKYRFAEAAKALYEFIWNDFCDWYIELVKYRLY--------------------NGNEAE 664
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 719 QTGVRWCLLHTLDTSLRLLHPFMPFVTEEIWQTIKIQhsaiKESIMVSDYPKSLPR--DYQAEEDMSYIIEAVMGIRTIR 796
Cdd:TIGR00422 665 KKAARDTLYYVLDKALRLLHPFMPFITEEIWQHFKEG----ADSIMLQSYPVVDAEfvDEEAEKAFELLKEIIVSIRNLK 740
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 797 GELNISPSLKLNVSIKTFSQMAEKILKENVQYLKNLAKAGEIKIGMNIEKPECSATSVKSSMEIYVPLKGVLNITAEVDR 876
Cdd:TIGR00422 741 AESNIPPNAPLKVLLIYTEAETAERLKLNAVDIKGAINFSEVEVVIEKPEVTEAVVELVPGFEIIIPVKGLINKAKELAR 820
|
890 900 910 920
....*....|....*....|....*....|....*....|.
gi 1278345029 877 LKKEEAKVDVSIVSLNRKLFNEDFLQRAPREIIDKEKAKYE 917
Cdd:TIGR00422 821 LQKQLDKEKKEVIRIEGKLENEGFVKKAPKEVIEKEKEKLE 861
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
2-937 |
0e+00 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 1128.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 2 LEKGYNPQGIEERWYEYWVSKGYFKPD--PDLKGSFySLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPG 79
Cdd:PRK14900 15 LAKGYEHREVEARWYPFWQERGYFHGDehDRTRPPF-SIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLWLPG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 80 TDHAGIATQNVVEKQLAST-GLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFV 158
Cdd:PRK14900 94 TDHAGIATQMIVEKELKKTeKKSRHDLGREAFLERVWAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVREVFV 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 159 RLYEEGLIYRDNRLINWCPRCNTALSDLEVEYEEL-EGKLTYIKYPLTppipplarggdNKRGYITVATTRPETMLGDTA 237
Cdd:PRK14900 174 RLHEEGLIYREKKLINWCPDCRTALSDLEVEHEEAhQGELWSFAYPLA-----------DGSGEIVVATTRPETMLGDTA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 238 VAVNPEDSRYQKFIGKTINLPLTDRKILIISDHA-VDPSFGTGAVKVTPAHDFNDEAIAKKQipPLEFITVIGADGLMTV 316
Cdd:PRK14900 243 VAVHPLDPRYMALHGKKVRHPITGRTFPIVADAIlVDPKFGTGAVKVTPAHDFNDFEVGKRH--GLEMITVIGPDGRMTA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 317 NAGnRYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKEGKINIIP 396
Cdd:PRK14900 321 EAG-PLAGLDRFEARKEVKRLLAEQGLDRGAKPHVLPLGRCQRSATILEPLLSDQWYVRIEPLARPAIEAVEQGRTRFIP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 397 KTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQKMQnakckmqngVIVSRDVPQVCPYCSSEELIQDEDVLDTWFSSA 476
Cdd:PRK14900 400 EQWTNTYMAWMRNIHDWCISRQLWWGHQIPAWYCPDGH---------VTVARETPEACSTCGKAELRQDEDVLDTWFSSG 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 477 LWPFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPL 556
Cdd:PRK14900 471 LWPFSTMGWPEQTDTLRTFYPTSVMETGHDIIFFWVARMMMMGLHFMGEVPFRTVYLHPMVRDEKGQKMSKTKGNVIDPL 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 557 IMIDRYGTDAFRFTLAAFTAQGRDIKFSEKRVEGYRHFVNKLWNAARFIMMNTNPPTpplekggkggfekEGVERITHTP 636
Cdd:PRK14900 551 VITEQYGADALRFTLAALTAQGRDIKLAKERIEGYRAFANKLWNASRFALMNLSGYQ-------------ERGEDPARLA 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 637 HDLASKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEInpptqpslsrgegKGGDgnseprtP 716
Cdd:PRK14900 618 RTPADRWILARLQRAVNETVEALEAFRFNDAANAVYAFVWHELCDWYIELAKEAL-------------ASED-------P 677
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 717 NSQTGVRWCLLHTLDTSLRLLHPFMPFVTEEIWQTIKIQHSA--IKESIMVSDYPKSLPRDYQAEEDMSYIIEAVMGIRT 794
Cdd:PRK14900 678 EARRSVQAVLVHCLQTSYRLLHPFMPFITEELWHVLRAQVGAsaWADSVLAAEYPRKGEADEAAEAAFRPVLGIIDAVRN 757
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 795 IRGELNISPSLKLNVSIKTFSQMAEKILKENVQ-----YLKNLA--KAGEIKIGMNIEKPECSATSVKSSMEIYVPLKGV 867
Cdd:PRK14900 758 IRGEMGIPWKVKLGAQAPVEIAVADPALRDLLQagelaRVHRVAgvEGSRLVVAAATAPAPQSAVGVGPGFEVRVPLAGV 837
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 868 LNITAEVDRLKKEEAKVDVSIVSLNRKLFNEDFLQRAPREIIDKEKAKYEELIIIKKRILESIKMLKDVE 937
Cdd:PRK14900 838 IDLAAETARVDKEIGKVDQDLAVLERKLQNPSFVQNAPPAVVEKDRARAEELREKRGKLEAHRAMLSGSE 907
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
2-934 |
0e+00 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 993.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 2 LEKGYNPQGIEERWYEYWVSKGYFKPDPDLK----GSFYSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWL 77
Cdd:PTZ00419 24 MAASYDPKEVESGWYEWWEKSGFFKPAEDAKslnsGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDETLWV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 78 PGTDHAGIATQNVVEKQLAST-GLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREV 156
Cdd:PTZ00419 104 PGTDHAGIATQVVVEKKLMKEeNKTRHDLGREEFLKKVWEWKDKHGNNICNQLRRLGSSLDWSREVFTMDEQRSKAVKEA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 157 FVRLYEEGLIYRDNRLINWCPRCNTALSDLEVEYEELE----------------GKLTYIKYPLTppipplarggDNKRG 220
Cdd:PTZ00419 184 FVRLYEDGLIYRDTRLVNWCCYLKTAISDIEVEFEEIEkptkitipgydkkvevGVLWHFAYPLE----------DSGQE 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 221 YITVATTRPETMLGDTAVAVNPEDSRYQKFIGKTINLPLT-DRKILIISDHA-VDPSFGTGAVKVTPAHDFNDEAIAKKQ 298
Cdd:PTZ00419 254 EIVVATTRIETMLGDVAVAVHPKDERYKKLHGKELIHPFIpDRKIPIIADDElVDMEFGTGAVKITPAHDPNDYEIAKRH 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 299 ipPLEFITVIGADGLMTVNAGnRYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQS 378
Cdd:PTZ00419 334 --NLPFINIFTLDGKINENGG-EFAGMHRFDCRRKIEEELKEMGLLRDKVPNPMRLPRCSRSGDIVEPMLIPQWYVNCKD 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 379 IAKDAIRVVKEGKINIIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPVW-YCQKMQNAKCKMQNGVIVSRD-------V 450
Cdd:PTZ00419 411 MAKRAVEAVRNGELKIIPSSHENVWYHWLENIQDWCISRQLWWGHRIPAYrVISKGPETDPSDEEPWVVARSeeealekA 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 451 PQVCPYCSSE-ELIQDEDVLDTWFSSALWPFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFR 529
Cdd:PTZ00419 491 KKKFGLSEEDfELEQDEDVLDTWFSSGLFPFSTLGWPDQTDDLQRFFPTSLLETGSDILFFWVARMVMMSLHLTDKLPFK 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 530 DVYIHALVRDLKGQKMSKSKGNVVDPLIMID-------------------------------------RYGTDAFRFTLA 572
Cdd:PTZ00419 571 TVFLHAMVRDSQGEKMSKSKGNVIDPLEVIEgislqdlnqklyegnlpekeikraielqkkefpngipECGTDALRFGLL 650
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 573 AFTAQGRDIKFSEKRVEGYRHFVNKLWNAARFIMMNTNPPTPPLEKGGKGGFEKEGVERIthtphdlaSKWILSRLAAIA 652
Cdd:PTZ00419 651 AYTQQGRNINLDINRVVGYRHFCNKLWNAVKFALMKLLKDFNLPNSTLFKPNNVESLPWE--------DKWILHRLNVAI 722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 653 DDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEInpptqpslsrgegkggdgNSEPRTPNSQtGVRWCLLHTLDT 732
Cdd:PTZ00419 723 KEVTEGFKEYDFSEATQATYNFWLYELCDVYLELIKPRL------------------SKQSDGERKQ-HAQDVLHTVLDI 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 733 SLRLLHPFMPFVTEEIWQTIKiQHSAIKESIMVSDYPKSLP--RDYQAEEDMSYIIEAVMGIRTIRGELNISPSLKLNVS 810
Cdd:PTZ00419 784 GLRLLHPMMPFITEELYQRLP-NYLRKSESISIAKYPQPNPgwNNEALDEEMKIIMSIVKSIRSLIATLGIPNKTKPDCY 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 811 IKTFSQMAEKILKENVQYLKNLAKAGEIKIGMNIE-----KPECSATSVKSSMEIYVPLKGVLNITAEVDRLKKEEAKVD 885
Cdd:PTZ00419 863 VTAKDAELIELIESAENLISTLAKIGSVSVIPPIEeeaevPKGCGFDVVDNKVIIYLNLDEFIDLKKELAKLEKKLAKLQ 942
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*....
gi 1278345029 886 VSIVSLNRKLFNEDFLQRAPREIIDKEKAKYEELIIIKKRILESIKMLK 934
Cdd:PTZ00419 943 KSLESYLKKISIPNYEDKVPEDVRKLNDEKIDELNEEIKQLEQAIEELK 991
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
12-926 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 850.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 12 EERWYEYWVSKGYFKPDPDLKGSFYSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVV 91
Cdd:PLN02943 66 EERIYNWWESQGYFKPNFDRGGDPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGTDHAGIATQLVV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 92 EKQLASTGLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNR 171
Cdd:PLN02943 146 EKMLASEGIKRTDLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVRLHEKGLIYQGSY 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 172 LINWCPRCNTALSDLEVEYEELEGKLTYIKYPLTppipplarGGDNKrgYITVATTRPETMLGDTAVAVNPEDSRYQKFI 251
Cdd:PLN02943 226 MVNWSPNLQTAVSDLEVEYSEEPGTLYYIKYRVA--------GGSED--FLTIATTRPETLFGDVAIAVNPEDDRYSKYI 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 252 GKTINLPLT-DRKILIISDHAVDPSFGTGAVKVTPAHDFNDEAIAKKQipPLEFITVIGADGLMtvnagNRYAGLDRYEC 330
Cdd:PLN02943 296 GKMAIVPMTyGRHVPIIADRYVDKDFGTGVLKISPGHDHNDYLLARKL--GLPILNVMNKDGTL-----NEVAGLYWFEA 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 331 RKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKEGKINIIPKTWENTYFAWMEDI 410
Cdd:PLN02943 369 REKLWSDLEETGLAVKKEPHTLRVPRSQRGGEVIEPLVSKQWFVTMEPLAEKALKAVENGELTIIPERFEKIYNHWLSNI 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 411 KDWCISRQIWWGHRIPVWYcqkMQNAKCkmQNGVIVSRDVPQVC-----PYCSSEELIQDEDVLDTWFSSALWPFSTLGW 485
Cdd:PLN02943 449 KDWCISRQLWWGHRIPVWY---IVGKDC--EEDYIVARSAEEALekareKYGKDVEIYQDPDVLDTWFSSALWPFSTLGW 523
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 486 PD-NTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGT 564
Cdd:PLN02943 524 PDvSAEDFKKFYPTTVLETGHDILFFWVARMVMMGIEFTGTVPFSYVYLHGLIRDSQGRKMSKTLGNVIDPLDTIKEFGT 603
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 565 DAFRFTLAAFTAqGRDIKFSEKRVEGYRHFVNKLWNAARFIMMNTNPPTPPLEKGGKGGFEKEGVERITHTPhdLASKWI 644
Cdd:PLN02943 604 DALRFTLALGTA-GQDLNLSTERLTSNKAFTNKLWNAGKFVLQNLPSQSDTSAWEHILACKFDKEESLLSLP--LPECWV 680
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 645 LSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEINpptqpslsrgegKGGDGNSEPRTpnsqtgvRW 724
Cdd:PLN02943 681 VSKLHELIDSVTTSYDKYFFGDVGREIYDFFWSDFADWYIEASKTRLY------------HSGDNSALSRA-------QA 741
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 725 CLLHTLDTSLRLLHPFMPFVTEEIWQTIKIQhsaiKESIMVSDYPK-SLPRDYQAEEDMSYIIEAVMGIRTIRGELNISP 803
Cdd:PLN02943 742 VLLYVFENILKLLHPFMPFVTEELWQALPYR----KEALIVSPWPQtSLPKDLKSIKRFENLQSLTRAIRNARAEYSVEP 817
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 804 SLKLNVSIKTFSQMAEKILKENvQYLKNLAKAGEIKIGMNIEKPECSATSV----KSSMEIYVPLKGVLNITAEVDRLKK 879
Cdd:PLN02943 818 AKRISASIVASAEVIEYISKEK-EVLALLSRLDLQNVHFTDSPPGDANQSVhlvaSEGLEAYLPLADMVDISAEVERLSK 896
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|.
gi 1278345029 880 EEAKVDVSIVSLNRKLFNEDFLQRAPREIID--KEKAKY--EELIIIKKRI 926
Cdd:PLN02943 897 RLSKMQTEYDALAARLSSPKFVEKAPEDVVRgvREKAAEaeEKIKLTKNRL 947
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
2-924 |
0e+00 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 790.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 2 LEKGYNPQGIEERWYEYWVSKGYFKPDPDLKGSFYSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTD 81
Cdd:PLN02381 96 MAKQYSPSAVEKSWYAWWEKSGYFGADAKSSKPPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVPGVD 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 82 HAGIATQNVVEKQLA-STGLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRL 160
Cdd:PLN02381 176 HAGIATQVVVEKKLMrERHLTRHDIGREEFVSEVWKWKDEYGGTILNQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRL 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 161 YEEGLIYRDNRLINWCPRCNTALSDLEVEYEELEGKlTYIKYP----------LTPPIPPLARGgdnkRGYITVATTRPE 230
Cdd:PLN02381 256 YKEGLIYRDIRLVNWDCTLRTAISDVEVDYIDIKER-TLLKVPgydkpvefgvLTSFAYPLEGG----LGEIVVATTRIE 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 231 TMLGDTAVAVNPEDSRYQKFIGKTINLPLTDRKILIISDHA-VDPSFGTGAVKVTPAHDFNDEAIAKKQipPLEFITVIG 309
Cdd:PLN02381 331 TMLGDTAIAIHPDDERYKHLHGKFAVHPFNGRKLPIICDAIlVDPNFGTGAVKITPAHDPNDFEVGKRH--NLEFINIFT 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 310 ADGLMTVNAGNRYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKE 389
Cdd:PLN02381 409 DDGKINSNGGSEFAGMPRFAAREAVIEALQKKGLYRGAKNNEMRLGLCSRTNDVVEPMIKPQWFVNCSSMAKQALDAAID 488
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 390 G---KINIIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYC--QKMQNAKCKMQNG-VIVSRDVPQVCPYCSSE--- 460
Cdd:PLN02381 489 GenkKLEFIPKQYLAEWKRWLENIRDWCISRQLWWGHRIPAWYVtlEDDQLKELGSYNDhWVVARNESDALLEASQKfpg 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 461 ---ELIQDEDVLDTWFSSALWPFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFRDVYIHALV 537
Cdd:PLN02381 569 kkfELSQDPDVLDTWFSSGLFPLSVLGWPDDTDDLKAFYPTSVLETGHDILFFWVARMVMMGMQLGGDVPFRKVYLHPMI 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 538 RDLKGQKMSKSKGNVVDPLIMID-------------------------------------RYGTDAFRFTLAAFTAQGRD 580
Cdd:PLN02381 649 RDAHGRKMSKSLGNVIDPLEVINgisleglhkrleegnldpkelvvakegqkkdfpngiaECGTDALRFALVSYTAQSDK 728
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 581 IKFSEKRVEGYRHFVNKLWNAARFIMMN-TNPPTPPLEkggkggfekegverITHTPHDLASKWILSRL-AAIADDINrA 658
Cdd:PLN02381 729 INLDILRVVGYRQWCNKLWNAVRFAMSKlGDDYTPPAT--------------LSVETMPFSCKWILSVLnKAISKTVS-S 793
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 659 LEEYRFNDAASSIYQFVWHEFCDWYLEMAKseinpptqPSLSrgegkgGDGNSEPRTPNSQTGVRWCllhTLDTSLRLLH 738
Cdd:PLN02381 794 LDAYEFSDAASTVYSWWQYQFCDVFIEAIK--------PYFA------GDNPEFASERAAAQDTLWI---CLDTGLRLLH 856
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 739 PFMPFVTEEIWQTI-KIQHSAIKESIMVSDYPKSLP--RDYQAEEDMSYIIEAVMGIRTIRGELniSPSLKlNVSIKTF- 814
Cdd:PLN02381 857 PFMPFVTEELWQRLpQPKDHTRKDSIMISEYPSAVEawTNEKVEYEMDLVLSTVKCLRSLRAEV--LEKQK-NERLPAFa 933
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 815 ---SQMAEKILKENVQYLKNLAKAGEIKI---GMNIEKPECSATSVKSSMEIYVPLKGVLNITAEVDRLKKEEAKVDVSI 888
Cdd:PLN02381 934 lcrNQEIAAIIKSHQLEILTLANLSSLKVllsENDAPPAGCAFENVNENLKVYLQAQGAVNAEAELEKLRNKMDEIQKQQ 1013
|
970 980 990 1000
....*....|....*....|....*....|....*....|
gi 1278345029 889 VSLNRKLFNEDFLQRAPREIIDKEKAK----YEELIIIKK 924
Cdd:PLN02381 1014 EKLEKKMNASGYKEKVPANIQEEDARKltklLQELEFFEK 1053
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
15-584 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 674.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 15 WYEYWVSKGYFKPDPDL---KGSFySLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVV 91
Cdd:pfam00133 2 IYEFWDEQGYFKPELEKrkgKPSF-TIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEQVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 92 EKQLASTG-LDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDN 170
Cdd:pfam00133 81 EKKLGIKEkKTRHKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRGK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 171 RLINWCPRCNTALSDLEVEYEELEGKLTYIKYPLTppipplarggDNKRGYITVATTRPETMLGDTAVAVNPE------- 243
Cdd:pfam00133 161 KLVNWSPALNTALSNLEVEYKDVKGPSIHVAFPLA----------DDEGASLVIWTTTPWTLPGNTAVAVNPEfdyvitg 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 244 ------------------------DSRYQKFIGKTINLPLTDRKILIISDHAVDPSFGTGAVKVTPAHDFNDEAIAKKQi 299
Cdd:pfam00133 231 egyilaeallkslykkgtdkkileDFRGKELEGKEAIHPFVNREIPIITDDYVDMEFGTGAVHIAPAHGENDYEVGQRH- 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 300 pPLEFITVIGADGLMTVNAGNrYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSI 379
Cdd:pfam00133 310 -NLEVINPVDDDGTFTEEAPD-FQGVYRFDARKKIVELLTEKGLLLKIEPFTHSYPFCWRSGTPIIPRATPQWFVRMDEL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 380 AKDAIRVVKegKINIIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQKMQNAKCKMQNGVIVSRDV--------- 450
Cdd:pfam00133 388 ADQALEAVE--KVQFVPKSGEKRYFNWLANIQDWCISRQRWWGHPIPAWVSKDTEEVVCRGELFELVAGRFeeegsikwl 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 451 ---PQVCPYCSSEELIQDEDVLDTWFSSALWPFSTLGWPD-NTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDV 526
Cdd:pfam00133 466 hreAKDKLGYGKGTLEQDEDVLDTWFSSGSWPFSTLGWPFvNTEEFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGSV 545
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 1278345029 527 PFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLaAFTAQGRDIKFS 584
Cdd:pfam00133 546 PFKNVLVHGLVRDEQGRKMSKSLGNVIDPLDVIDKYGADALRLWL-ANSDYGRDINLS 602
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
1-840 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 612.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 1 MLEKGYNPQGIEERWYEYWVSKGYFKPDPDLKGSFYSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGT 80
Cdd:PRK13208 5 ELPKKYDPEELEEKWQKIWEEEGTYKFDPDERKPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFFPQGW 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 81 DHAGIATQNVVEKQLastGLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRL 160
Cdd:PRK13208 85 DDNGLPTERKVEKYY---GIRKDDISREEFIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQTISPEYRRISQKSFLDL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 161 YEEGLIYRDNRLINWCPRCNTALSDLEVEYEELEGKLTYIKYpltppipPLARGGDnkrgyITVATTRPETMLGDTAVAV 240
Cdd:PRK13208 162 YKKGLIYRAEAPVLWCPRCETAIAQAEVEYREREGKLNYIKF-------PVEDGEE-----IEIATTRPELLPACVAVVV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 241 NPEDSRYQKFIGKTINLPLTDRKILIISDHAVDPSFGTGAVKVTPAHDFNDEAIAKKQIPPLefITVIGADGLMTVNAGn 320
Cdd:PRK13208 230 HPDDERYKHLVGKTAIVPLFGVEVPILADPLVDPDFGTGAVMICTFGDKTDVTWWRELNLPT--RIIIDEDGRMTEAAG- 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 321 RYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKEgkINIIPKTWE 400
Cdd:PRK13208 307 KLAGLTIEEARKKIVEDLKSGGLLGKQEPIKHNVKFCERCDTPLEILVTRQWFIKVLDLKEELLERGKE--INWYPEHMR 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 401 NTYFAWMEDIK-DWCISRQIWWGHRIPVWYCqkmqnAKCkmqnGVIV-----------SRDVPQV--CPYCSSEELIQDE 466
Cdd:PRK13208 385 VRLENWIEGLNwDWCISRQRYFGTPIPVWYC-----KDC----GHPIlpdeedlpvdpTKDEPPGykCPQCGSPGFEGET 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 467 DVLDTWFSSALWPFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFW----VARMIMMglkfMGDVPFRDVYIHALVRDLKG 542
Cdd:PRK13208 456 DVMDTWATSSITPLIVTGWERDEDLFEKVFPMDLRPQGHDIIRTWlfytILRAYLL----TGKLPWKNIMISGMVLDPDG 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 543 QKMSKSKGNVVDPLIMIDRYGTDAFRFTlAAFTAQGRDIKFSEKRVEGYRHFVNKLWNAARFIMMNTNPPTPPLekggkg 622
Cdd:PRK13208 532 KKMSKSKGNVVTPEELLEKYGADAVRYW-AASARLGSDTPFDEKQVKIGRRLLTKLWNASRFVLHFSADPEPDK------ 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 623 gfekegvERITHTphdlASKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEInpptqpslsrg 702
Cdd:PRK13208 605 -------AEVLEP----LDRWILAKLAKVVEKATEALENYDFAKALEEIESFFWHVFCDDYLELVKSRA----------- 662
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 703 egKGGDGnseprtPNSQTGVRWCLLHTLDTSLRLLHPFMPFVTEEIWQTIKiqhsaiKESIMVSDYPKSLP--RDYQAEE 780
Cdd:PRK13208 663 --YGEDE------EEEQKSARYTLYTVLDTLLRLLAPFLPFITEEVWSWLY------GGSVHRASWPEPDEelIDEEDEE 728
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278345029 781 DMSYIIEAVMGIRTIRGELNIS---PSLKLNVSIKTFSQMAEKILKEnvqyLKNLAKAGEIKI 840
Cdd:PRK13208 729 LGELAKEILSAVRKYKSEAGLSlnaPLKKVEVYGPADLELLEAAEED----LKAAGNIEELEL 787
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
36-583 |
0e+00 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 608.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 36 YSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVEKQLASTGLDRDKLGRNAFIERVW 115
Cdd:cd00817 3 FVIDTPPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVVVEKKLGIEGKTRHDLGREEFLEKCW 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 116 KWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSDLEVeyeeleg 195
Cdd:cd00817 83 EWKEESGGKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKLRTAISDIEV------- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 196 kltyikypltppipplarggdnkrgyitvattrpetmlgdtavavnpedsryqkfigktinlpltdrkiliisdhavdps 275
Cdd:cd00817 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 276 fgtgavkvtpahdfndeaiakkqipplefitvigadglmtvnagnryagldryecrklvikdlkvlnllekeelykyavg 355
Cdd:cd00817 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 356 hCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKEGKINIIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQKmqn 435
Cdd:cd00817 156 -CSRSGDVIEPLLKPQWFVKVKDLAKKALEAVKEGDIKFVPERMEKRYENWLENIRDWCISRQLWWGHRIPAWYCKD--- 231
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 436 akckmQNGVIVSRD--------VPQVCPYCSSEELIQDEDVLDTWFSSALWPFSTLGWPDNTDDLKTFYPTSVLVTGFDI 507
Cdd:cd00817 232 -----GGHWVVAREedeaidkaAPEACVPCGGEELKQDEDVLDTWFSSSLWPFSTLGWPEETKDLKKFYPTSLLVTGHDI 306
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278345029 508 IFFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAFTAQGRDIKF 583
Cdd:cd00817 307 IFFWVARMIMRGLKLTGKLPFKEVYLHGLVRDEDGRKMSKSLGNVIDPLDVIDGYGADALRFTLASAATQGRDINL 382
|
|
| ileS |
TIGR00392 |
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ... |
1-802 |
5.97e-118 |
|
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ligase and is particularly closely related to the valyl tRNA synthetase. This model may recognize IleS from every species, including eukaryotic cytosolic and mitochondrial forms. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273054 [Multi-domain] Cd Length: 861 Bit Score: 380.95 E-value: 5.97e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 1 MLEKGYNPQGIEERWYEYWVSKGYF---KPDPDLKGSFYsLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWL 77
Cdd:TIGR00392 1 KFPMRGNLSKREEKILAFWQENDIFekvKKLNKGKPEFI-FHDGPPYANGSIHLGHALNKILKDIILRYKTMQGFNVTRK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 78 PGTDHAGIATQNVVEKQLASTGLDR-DKLGRNAFIER----VWKWKAEYGGkiihQLKRLGASCDWSRERFTLDDGLSKA 152
Cdd:TIGR00392 80 PGWDTHGLPIEHKVEKKLGISGKKEiSSLEIEEFREKcrefALKQIEEQRE----QFQRLGVWGDWENPYKTMDPSYEES 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 153 VREVFVRLYEEGLIYRDNRLINWCPRCNTALSDLEVEYEELEGKLT----YIKYPLTppipplarGGDN-----KRGYIT 223
Cdd:TIGR00392 156 QWWLFKEAHEKGLLYRGLKPVYWSPRCRTALAEAEVEYKENYKDVKdpsiYVKFPVK--------KDKKtylkvKLSSLL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 224 VATTRPETMLGDTAVAVNPE--------DSRYQKFI------------------------GKTINL-----PLTDRK--- 263
Cdd:TIGR00392 228 IWTTTPWTLPSNLAIAVHPDfeyalvqdNTKVEYFIlakklveklynkagsdyeiiktfkGSDLEGleyehPLYDFVsql 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 264 -----ILIISDHAVDPSfGTGAVKVTPAHDFNDEAIAKKQipPLEFITVIGADGLMTVNAGN------RYAGLDRYECRK 332
Cdd:TIGR00392 308 kegapVVIGGDHVTTED-GTGIVHTAPGHGEEDYEIGKKY--GLEVLSPVDEKGVYTEGVNDfqgrfvKDADKDIIKANK 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 333 LVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVKegKINIIPKTWENTYFAWMEDIKD 412
Cdd:TIGR00392 385 IIIEQLKDKGLLLKAEKITHSYPHCWRTKTPVIYRATEQWFIKTKDIKDQMLEQIK--KVNWVPEWGEGRFGNWLENRPD 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 413 WCISRQIWWGHRIPVWYCQKMQNAKC---------KMQNGVIVS------RDV--PQVCPYCSSEELIQDEDVLDTWFSS 475
Cdd:TIGR00392 463 WCISRQRYWGIPIPIWYCEDTGEPIVvgsieelieLIELKGIDAwfedlhRDFldKITLKSGDGGEYRRVPDVLDVWFDS 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 476 ALWPFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDP 555
Cdd:TIGR00392 543 GSMPYASIHYPFENEKFKEVFPADFILEGSDQTRGWFYSSLAIGTALFGQAPYKNVITHGFTLDEKGRKMSKSLGNVVDP 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 556 LIMIDRYGTDAFRFTLaAFTAQGRDIKFSE---KRVEgyRHFVNKLWNAARFIM--MNTNPPTPPlekggkggfeKEGVE 630
Cdd:TIGR00392 623 LKVINKYGADILRLYV-ASSDPWEDLRFSDeilKQVV--EKYRKIRWNTYRFLLtyANLDKFDPL----------FNSVA 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 631 RITHTPHDlasKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEINpptqpslsrgegkgGDGN 710
Cdd:TIGR00392 690 VEKFPEED---RWILSRLNSLVEEVNEALEKYNFHKVLRALQDFIVEELSNWYIRIIRDRLY--------------CEAK 752
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 711 SEPRTPNSQTgvrwcLLHTLDTSLRLLHPFMPFVTEEIWQTIKIQHSaiKESIMVSDYPK--SLPRDYQAEEDMSYIIEA 788
Cdd:TIGR00392 753 DNDKRAAQTT-----LYYALLTLVRLLAPFLPHTAEEIYQNLPGGEE--EESVHLNLWPEvdEEFIDEALEANMAIVREI 825
|
890
....*....|....
gi 1278345029 789 VMGIRTIRGELNIS 802
Cdd:TIGR00392 826 VEAFLALRDAANKK 839
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
42-789 |
1.54e-107 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 354.77 E-value: 1.54e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 42 PPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTD-HaGIATQNVVEKQLASTGLDRDKLGRNAFIER----VWK 116
Cdd:COG0060 54 PPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPYVPGWDcH-GLPIELKVEKELGIKKKDIEKVGIAEFREKcreyALK 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 117 WKAEYggkiIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSDLEVEYEELEGK 196
Cdd:COG0060 133 YVDEQ----REDFKRLGVWGDWDNPYLTMDPEYEESIWWALKKLYEKGLLYKGLKPVPWCPRCGTALAEAEVEYKDVTSP 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 197 LTYIKYPLTPPIPPLARGGdnkrGYITVATTRPETMLGDTAVAVNPE----------DSRY------------------- 247
Cdd:COG0060 209 SIYVKFPVKDEKALLLLED----AYLVIWTTTPWTLPANLAVAVHPDidyvlvevtgGERLilaealveavlkelgiedy 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 248 ---QKFIGKT----------INLPLTDRKILIIS-DHaVDPSFGTGAVKVTPAH---DFNdeaIAKK-QIPPLEfitVIG 309
Cdd:COG0060 285 evlATFKGAEleglryehpfYYVVGYDRAHPVILgDY-VTTEDGTGIVHTAPGHgedDFE---VGKKyGLPVLN---PVD 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 310 ADGLMTVNAGnRYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTitePL---STPQWYVNVQSIAKDAIRV 386
Cdd:COG0060 358 DDGRFTEEAP-LFAGLFVKDANPAIIEDLKERGALLAREKITHSYPHCWRCKT---PLiyrATPQWFISMDKLRDRALEA 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 387 VKegKINIIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQKMQNAKCKMQngVIVSRD----------------- 449
Cdd:COG0060 434 IE--KVNWIPEWGEGRFGNMLENRPDWCISRQRYWGVPIPIWVCEDCGELHRTEE--VIGSVAelleeegadawfeldlh 509
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 450 ---VPQ--VCPYCSSEeLIQDEDVLDTWFSSALWPFSTLgwpDNTDDLKT---------------FYptSVLVTGfdiif 509
Cdd:COG0060 510 rpfLDEtlKCPKCGGT-MRRVPDVLDVWFDSGSMHFAVL---ENREELHFpadfylegsdqtrgwFY--SSLLTS----- 578
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 510 fwvarmimMGLKfmGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAfTAQGRDIKFSEKRVE 589
Cdd:COG0060 579 --------TALF--GRAPYKNVLTHGFVLDEDGRKMSKSLGNVVDPQEVIDKYGADILRLWVAS-SDYWGDLRFSDEILK 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 590 GYRHFVNKLWNAARFIMMNTNPPTPplekggkggfEKEGVErithtPHDLAS--KWILSRLAAIADDINRALEEYRFNDA 667
Cdd:COG0060 648 EVRDVYRRLRNTYRFLLANLDDFDP----------AEDAVP-----YEDLPEldRWILSRLNELIKEVTEAYDNYDFHRA 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 668 ASSIYQFVWHEFCDWYLEMAK-----SEINpptqpSLSRgegkggdgnseprtpnsqTGVRWCLLHTLDTSLRLLHPFMP 742
Cdd:COG0060 713 YRALHNFCVEDLSNWYLDISKdrlytEAAD-----SLDR------------------RAAQTTLYEVLETLVRLLAPILP 769
|
810 820 830 840
....*....|....*....|....*....|....*....|....*....
gi 1278345029 743 FVTEEIWQTIKiqhSAIKESIMVSDYPKSLP--RDYQAEEDMSYIIEAV 789
Cdd:COG0060 770 FTAEEIWQNLP---GEAEESVHLADWPEVDEelIDEELEAKWDLVREVR 815
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
36-583 |
6.79e-73 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 242.71 E-value: 6.79e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 36 YSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVEKQLastGLDRDKLGRNAFIERVW 115
Cdd:cd00668 2 FYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAERKG---GRKKKTIWIEEFREDPK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 116 KWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYrdnrlinwcprcntalsdleveyeeleg 195
Cdd:cd00668 79 EFVEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIY---------------------------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 196 kltyikypltppipplarggdnkRGYITVAttrpetmlgdtavavnpedsryqkfigktinlpltdrkiliisdhavdps 275
Cdd:cd00668 131 -----------------------RGTHPVR-------------------------------------------------- 137
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 276 fgtgavkvtpahdfndeaiakkqipplefitvigadglmtvnagnryagldryecrklvikdlkvlnllekeelykyavg 355
Cdd:cd00668 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 356 hcyrcktiteplSTPQWYVNVQSIAKDAIRVVKEGKIniIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPvwycqkmqn 435
Cdd:cd00668 138 ------------ITEQWFFDMPKFKEKLLKALRRGKI--VPEHVKNRMEAWLESLLDWAISRQRYWGTPLP--------- 194
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 436 akckmqngvivsrdvpqvcpycsseeliqdEDVLDTWFSSALWPFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARM 515
Cdd:cd00668 195 ------------------------------EDVFDVWFDSGIGPLGSLGYPEEKEWFKDSYPADWHLIGKDILRGWANFW 244
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278345029 516 IMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAFTAQGRDIKF 583
Cdd:cd00668 245 ITMLVALFGEIPPKNLLVHGFVLDEGGQKMSKSKGNVIDPSDVVEKYGADALRYYLTSLAPYGDDIRL 312
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
42-774 |
5.05e-61 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 225.04 E-value: 5.05e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 42 PPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIAtqnvVE-KQLAStgLDRDKlgRNAFIERVWKWKA- 119
Cdd:PLN02843 40 PPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHGLP----IElKVLQS--LDQEA--RKELTPIKLRAKAa 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 120 EYGGKII----HQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSDLEVEYEELE- 194
Cdd:PLN02843 112 KFAKKTVdtqrESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLNGYIYRGRKPVHWSPSSRTALAEAELEYPEGHv 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 195 GKLTYIKYPLTPPIPPLARGGDNKRGYITVA--TTRPETMLGDTAVAVNPE------------------DSRYQKFIGKT 254
Cdd:PLN02843 192 SKSIYVAFPVVSPSETSPEELEEFLPGLSLAiwTTTPWTMPANAAVAVNDKlqysvvevqsfsedestsGGNKKKRPGNV 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 255 INL------------------------------------------PLTDRK--ILIISDHAVDPSfGTGAVKVTPAHDFN 290
Cdd:PLN02843 272 LKEqqklflivatdlvpaleakwgvklvvlktfpgsdlegcryihPLYNREspVVIGGDYITTES-GTGLVHTAPGHGQE 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 291 DEAIAKKQIPPLefITVIGADGLMTVNAGnRYAGLDRY-ECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLST 369
Cdd:PLN02843 351 DYITGLKYGLPL--LSPVDDAGKFTEEAG-QFSGLSVLgEGNAAVVEALDEAGSLLMEEAYGHKYPYDWRTKKPTIFRAT 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 370 PQWYVNVQSI---AKDAIRVVKegkinIIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQK----MQNAKCKMQN 442
Cdd:PLN02843 428 EQWFASVEGFrqaALDAIDKVK-----WIPAQGENRIRAMVSGRSDWCISRQRTWGVPIPVFYHVEtkepLMNEETIAHV 502
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 443 GVIVSRDVPQVCPYCSSEELIQDE------------DVLDTWFSSAlwpFSTLGWPDNTDDLKtfYPTSVLVTGFDIIFF 510
Cdd:PLN02843 503 KSIVAQKGSDAWWYMDVEDLLPEKyrdkasdyekgtDTMDVWFDSG---SSWAGVLGSREGLS--YPADLYLEGSDQHRG 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 511 WVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMID---------RYGTDAFRFTLAAFTAQGrDI 581
Cdd:PLN02843 578 WFQSSLLTSVATKGKAPYKSVLTHGFVLDEKGFKMSKSLGNVVDPRLVIEggknqkqepAYGADVLRLWVASVDYTG-DV 656
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 582 KFS----EKRVEGYRhfvnKLWNAARFIMMNTNPPTPplekggkggfekegVERITHtpHDLAS--KWILSRLAAIADDI 655
Cdd:PLN02843 657 LIGpqilKQMSDIYR----KLRGTLRYLLGNLHDWKP--------------DNAVPY--EDLPSidKYALFQLENVVNEI 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 656 NRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEInpptqpslsrgegkGGDGNSEPRTPNSQTGVRWCLLHTldtsLR 735
Cdd:PLN02843 717 EESYDNYQFFKIFQILQRFTIVDLSNFYLDVAKDRL--------------YVGGTTSFTRRSCQTVLAAHLLSL----LR 778
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 1278345029 736 LLHPFMPFVTEEIWQTIKIQHSA-IKESIMVSDYPKSLPR 774
Cdd:PLN02843 779 AIAPILPHLAEDAWQNLPFQEDGsAAESVFEAGWPTPNEE 818
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
583-752 |
3.69e-59 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 198.16 E-value: 3.69e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 583 FSEKRVEGYRHFVNKLWNAARFIMMNTNPPTPPlekggkggfekegveRITHTPHDLASKWILSRLAAIADDINRALEEY 662
Cdd:cd07962 1 FDEKRVEGGRNFCNKLWNAARFVLMNLEDDDEP---------------EEDPESLSLADRWILSRLNKTVEEVTEALENY 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 663 RFNDAASSIYQFVWHEFCDWYLEMAKSEINPPTQPslsrgegkggdgnseprtpnSQTGVRWCLLHTLDTSLRLLHPFMP 742
Cdd:cd07962 66 RFSEAATALYEFFWNDFCDWYLELVKPRLYGEDEE--------------------EKKAARATLYYVLETILRLLHPFMP 125
|
170
....*....|
gi 1278345029 743 FVTEEIWQTI 752
Cdd:cd07962 126 FITEELWQRL 135
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
1-750 |
5.16e-49 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 187.18 E-value: 5.16e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 1 MLEKgYNPQGIEERWYEYWVSKGYFK-PDPDLKGSFYSLVI-PPPniTGSLHMGHALNTVLQDILSRWKRMSGYKVL--- 75
Cdd:COG0495 1 MQER-YNPKEIEKKWQKYWEENGTFKaDEDSSKPKYYVLDMfPYP--SGRLHMGHVRNYTIGDVVARYKRMQGYNVLhpm 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 76 -W----LPgtdhagiAtqnvvEkqlastgldrdklgrNAFIE-----RVWKWKAeyggkIIH---QLKRLGASCDWSRE- 141
Cdd:COG0495 78 gWdafgLP-------A-----E---------------NAAIKngvhpAEWTYEN-----IANmrrQLKRLGLSYDWSREi 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 142 --------RFTlddglskavREVFVRLYEEGLIYRDNRLINWCPRCNTAL------------SDLEVEYEELEG---KLT 198
Cdd:COG0495 126 atcdpeyyKWT---------QWIFLQLYEKGLAYRKEAPVNWCPVDQTVLaneqvidgrcwrCGAPVEKKELPQwflKIT 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 199 -Y---------------------------------IKYPLTppipplarGGDNKrgyITVATTRPETMLGDTAVAVNPE- 243
Cdd:COG0495 197 dYadellddldkldgwpekvktmqrnwigrsegaeVDFPVE--------GSDEK---ITVFTTRPDTLFGATFMVLAPEh 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 244 -----------DSRYQKFI----------------GKT--------INlPLTDRKILI-ISDHaVDPSFGTGAVKVTPAH 287
Cdd:COG0495 266 plvkelatpeqNAAVAAFIeeakkkseiertsetkEKTgvftglyaIN-PLTGEKIPIwIADY-VLMDYGTGAVMAVPAH 343
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 288 DFNDEAIAKK-QIPpleFITVIG---------------ADGLMtVNAGnRYAGLDRYECRKLVIKDLkvlnllEKEELYK 351
Cdd:COG0495 344 DQRDFEFAKKyGLP---IKQVIApedgddpdileeaytGDGVL-INSG-EFDGLDSEEAKEAIIEWL------EEKGLGK 412
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 352 YAVGhcYRcktiteplstpqwyvnvqsiakdairvvkegkiniipktwentyfawmedIKDWCISRQIWWGHRIPVWYCq 431
Cdd:COG0495 413 RKVN--YR--------------------------------------------------LRDWLISRQRYWGEPIPIIHC- 439
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 432 kmqnAKCKMqngVIVSRD---V--PQV---------------------CPYCSSE---ELiqdeDVLDTWF-SSalwpfs 481
Cdd:COG0495 440 ----EDCGV---VPVPEDqlpVelPEDvdfdptggsplarapewvnvtCPKCGGParrET----DTMDTFVdSS------ 502
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 482 tlgW-------PDNTDDLktfyptsvlvtgFD--IIFFW--V----------------ARMIMMGLKFMGDV----PFRD 530
Cdd:COG0495 503 ---WyylrytdPHNDEAP------------FDpeAANYWlpVdqyiggiehailhllyARFFTKVLRDLGLVsfdePFKR 567
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 531 VYIHALVRDL--------KGQKMSKSKGNVVDPLIMIDRYGTDAFR-FTLAAFTAQgRDIKFSEKRVEGYRHFVNKLWna 601
Cdd:COG0495 568 LLTQGMVLEVgkdgvvigGIEKMSKSKGNVVDPDEIIEKYGADTLRlFEMFAGPPE-RDLEWSDSGVEGAYRFLNRVW-- 644
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 602 aRFIMMNTNPPTPpleKGGKGGFEKEGVERITH-TphdlaskwilsrLAAIADDInralEEYRFNDAASSIYQFVWHefc 680
Cdd:COG0495 645 -RLVVDEAEALKL---DVADLSEADKELRRALHkT------------IKKVTEDI----ERLRFNTAIAALMELVNA--- 701
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 681 dwyleMAKSEINPPTQPSLSRgegkggdgnseprtpnsqtgvrwcllHTLDTSLRLLHPFMPFVTEEIWQ 750
Cdd:COG0495 702 -----LYKAKDSGEADRAVLR--------------------------EALETLVLLLAPFAPHIAEELWE 740
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
42-583 |
4.31e-46 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 168.95 E-value: 4.31e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 42 PPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVEKQLASTG-LDRDKLGRNAFIERVWKWKAE 120
Cdd:cd00818 9 PPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIELKVEKELGISGkKDIEKMGIAEFNAKCREFALR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 121 YGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWcprcntalsdleveyeelegkltyi 200
Cdd:cd00818 89 YVDEQEEQFQRLGVWVDWENPYKTMDPEYMESVWWVFKQLHEKGLLYRGYKVVPW------------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 201 kypltppipplarggdnkrgyitvattrpetmlgdtavavnpedsryqkfigktinlpltdrkiliisdhavdpsfgtga 280
Cdd:cd00818 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 281 vkvtpahdfndeaiakkqipPLefitvigadglmtvnagnryagldryecrklvikdlkvlnllekeeLYKyavghcyrc 360
Cdd:cd00818 144 --------------------PL----------------------------------------------IYR--------- 148
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 361 ktiteplSTPQWYVNVQSIAKDAIRVVKegKINIIPKTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQKmqnakckm 440
Cdd:cd00818 149 -------ATPQWFIRVTKIKDRLLEAND--KVNWIPEWVKNRFGNWLENRRDWCISRQRYWGTPIPVWYCED-------- 211
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 441 qngvivsrdvpqvcpyCSSEELIQDEDVLDTWFSSALWPFSTLGWPDNTDDLKTFYPTSVLVTGFDIIFFWVARMIMMGL 520
Cdd:cd00818 212 ----------------CGEVLVRRVPDVLDVWFDSGSMPYAQLHYPFENEDFEELFPADFILEGSDQTRGWFYSLLLLST 275
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278345029 521 KFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAFTAQGRDIKF 583
Cdd:cd00818 276 ALFGKAPYKNVIVHGFVLDEDGRKMSKSLGNYVDPQEVVDKYGADALRLWVASSDVYAEDLRF 338
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
7-753 |
1.70e-43 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 171.69 E-value: 1.70e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 7 NPQGIEE--RWYEYWVSKGYFKPDPDLKGS-----FYSlviPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPG 79
Cdd:PTZ00427 71 NPNIVEEeeKVLKYWKSIDAFNTSNKLAKNkkayiFYD---GPPFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFG 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 80 TDHAGIATQNVVEKQL-ASTGLDRDKLGRNAFIERVWKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFV 158
Cdd:PTZ00427 148 WDCHGLPIEYEIEKENnINKKEDILKMGIDVYNEKCRGIVLKYSNEWVKTVERIGRWIDFKNDYKTMDKTFMESVWWVFS 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 159 RLYEEGLIYRDNRLINWCPRCNTALSDLEVEYE----------------------ELEGKLTYIKYPLTPPIPPL----- 211
Cdd:PTZ00427 228 ELYKNNYVYKSFKVMPYSCKCNTPISNFELNLNykdtpdpsiiisfvlcsdfpkvEEECNIEEDKQLLGEKYSVLynnkr 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 212 ---ARGGDNKRGYITVA--------TTRPETMLGDTAVAVNP----------------------------------EDSR 246
Cdd:PTZ00427 308 ensNNGNNNSTNNVCYAqhseilawTTTPWTLPSNLALCVNEhftylrihhvksnrvvivgecrlewimkelkwnvEDLK 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 247 -YQKFIGKTIN----LPL----------TDRKILIISDHAVDPSFGTGAVKVTPAHDFNDEAIAKKQ--IPPLE--FITV 307
Cdd:PTZ00427 388 iVNRFKGKELKglryKPLftnfyekynfKERAYKILADDFVTDDAGTGIVHCAPTYGEDDFRVCKKNgvIDPEKniFIDP 467
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 308 IGADGLMTvNAGNRYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTITEPLSTPQWYVNVQSIAKDairVV 387
Cdd:PTZ00427 468 LDANGYFT-NEVEEVQNLYIKEADNVIKKKLKNENRLLSNNTIVHSYPFCWRSDTPLIYRAIPAWFIRVSNSTNE---LV 543
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 388 KEGKINI-IP-KTWENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQKMQNAKC-------KMQNGVIVSRDV-------- 450
Cdd:PTZ00427 544 KNNETTYwIPaHIKEKKFHNWIKDAKDWCISRNRYWGTPIPIWADEKMETVICvesikhlEELSGVKNINDLhrhfidhi 623
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 451 ----PQVCPYcssEELIQDEDVLDTWFSSALWPFSTLGWPDNT--DDLKTFYPTSVLVTGFDIIFFWVARMIMMGLKFMG 524
Cdd:PTZ00427 624 eiknPKGKTY---PKLKRIPEVFDCWFESGSMPYAKVHYPFSTekEDFHKIFPADFIAEGLDQTRGWFYTLLVISTLLFD 700
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 525 DVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAFTA-QGRDIKFSEKRV-EGYRHFVNKLWNAA 602
Cdd:PTZ00427 701 KAPFKNLICNGLVLASDGKKMSKRLKNYPDPLYILDKYGADSLRLYLINSVAvRAENLKFQEKGVnEVVKSFILPFYHSF 780
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 603 RFIMMNTNpptpplEKGGKGGFEKEGVERITHTPHDLASKWILSRLAAIADDINRALEEYRFNDAASSIYQFVwHEFCDW 682
Cdd:PTZ00427 781 RFFSQEVT------RYECLNKKQFLFNTDYIYKNDNIMDQWIFSSVQSLTKSVHTEMKAYKLYNVLPKLLQFI-ENLTNW 853
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278345029 683 YLEMAKseinpptqpslSRGEGKGGDGNSeprtpnsqtgvrwclLHTLDTSLRLLH-------PFMPFVTEEIWQTIK 753
Cdd:PTZ00427 854 YIRLNR-----------DRMRGSLGEENC---------------LQSLCTTYRTLHlftvlmaPFTPFITEYIYQQLR 905
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
49-839 |
7.69e-42 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 165.81 E-value: 7.69e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 49 LHMGHALNTVLQDILSRWKRMSGYKVLWlP------GTDHAGIAtqnvveKQLAStgldRDKLGRNAF-------IERVW 115
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLF-PmafhvtGTPILGIA------ERIAR----GDPETIELYkslygipEEELE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 116 KWK-----AEYGGKIIHQ-LKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTA------L 183
Cdd:PRK12300 70 KFKdpeyiVEYFSEEAKEdMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPvgdhdlL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 184 SDLEVEYEELegklTYIKYPltppipplaRGGDnkrGYITVATTRPETMLGDTAVAVNPEDS------------------ 245
Cdd:PRK12300 150 DGEEPEIVEY----TLIKFE---------ESED---LILPAATLRPETIFGVTNLWVNPDATyvkaevdgekwivskeaa 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 246 ---RYQ-------------KFIGKTINLPLTDRKILIISDHAVDPSFGTGAVKVTPAH---DF--------NDEAIAKKQ 298
Cdd:PRK12300 214 eklSFQdrdveiieeikgsELIGKKVKNPVTGKEVPILPADFVDPDNGTGVVMSVPAHapyDYvalrdlkkNKELLDVIE 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 299 IPPLefITVIGAD-----------------------------------GLMTVNAGnRYAGLDRYECRKLVIKDLKVLNL 343
Cdd:PRK12300 294 PIPL--IEVEGYGefpakevveklgiksqedpeleeatkevyraefhkGVLKENTG-EYAGKPVREAREKITKDLIEKGI 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 344 LEKeeLYKYAVGHCY-RC------KTITEplstpQWYVNV-----QSIAKDAIrvvkeGKINIIP----KTWENTYFaWM 407
Cdd:PRK12300 371 ADI--MYEFSNRPVYcRCgtecvvKVVKD-----QWFIDYsdpewKELAHKAL-----DNMEIIPeeyrKEFENTID-WL 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 408 ediKDWCISRQIWWGHRIPvW--------------YCQKMQNAKcKMQNGVIvsrdvpqvcpycSSEELIqdEDVLDTWF 473
Cdd:PRK12300 438 ---KDRACARRRGLGTRLP-WdeewiieslsdstiYMAYYTIAH-KIREYGI------------KPEQLT--PEFFDYVF 498
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 474 ---SSALWPFSTLGWPDNT-----DDLKTFYPTSVLVTGFDII-----FFW---VA--------RMIMmglkfmgdvpfr 529
Cdd:PRK12300 499 lgkGDPEEVSKKTGIPKEIleemrEEFLYWYPVDWRHSGKDLIpnhltFFIfnhVAifpeekwpRGIV------------ 566
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 530 dvyIHALVRdLKGQKMSKSKGNVVdPLI-MIDRYGTDAFRFTLAAFTAQGRDIKFSEKRVEGYRHFVNKLWN-AARFIMM 607
Cdd:PRK12300 567 ---VNGFVL-LEGKKMSKSKGNVI-PLRkAIEEYGADVVRLYLTSSAELLQDADWREKEVESVRRQLERFYElAKELIEI 641
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 608 NTNPPTpplekggkggfekegverithtphDLASKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFcDWYLEMa 687
Cdd:PRK12300 642 GGEEEL------------------------RFIDKWLLSRLNRIIKETTEAMESFQTRDAVQEAFYELLNDL-RWYLRR- 695
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 688 kseinpptqpslsrgegkGGDGNSEprtpnsqtgvrwCLLHTLDTSLRLLHPFMPFVTEEIWQTIKIQHSAIKESIMVSD 767
Cdd:PRK12300 696 ------------------VGEANNK------------VLREVLEIWIRLLAPFTPHLAEELWHKLGGEGFVSLEKWPEPD 745
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278345029 768 YPKSLPRDYQAEEDMSYIIEavmGIRTIRGELNISP-SLKLNVS----IKTFSQMAEKILKENVqyLKNLAKAGEIK 839
Cdd:PRK12300 746 ESKIDEEAELAEEYVKRLIE---DIREILKVAKIKPkKVYIYVApdwkYEVLEIAAENGDVKEA--IKELMKDEELR 817
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
642-811 |
1.16e-40 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 146.39 E-value: 1.16e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 642 KWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFCDWYLEMAKSEINpptqpslsrgegkGGDGNSEprtpnsqtg 721
Cdd:pfam08264 2 RWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLSDWYLELIKDRLY-------------GEEPDSR--------- 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 722 VRWCLLHTLDTSLRLLHPFMPFVTEEIWQtikiqhsaiKESIMVSDYPK-SLPRDYQAEEDMSYIIEAVMGIRTIRGELN 800
Cdd:pfam08264 60 AQTTLYEVLETLLRLLAPFMPFITEELWQ---------KESIHLAPWPEdAELEEAELEEAFELRQEIVQAIRKLRSELK 130
|
170
....*....|.
gi 1278345029 801 ISPSLKLNVSI 811
Cdd:pfam08264 131 IKKSLPLEVVI 141
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
42-793 |
1.98e-40 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 161.82 E-value: 1.98e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 42 PPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVEKQLASTGldRD---KLGRNAFIER----V 114
Cdd:PLN02882 46 PPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGWDCHGLPVEYEIDKKLGIKR--RDdvlKMGIDKYNEEcrsiV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 115 WKWKAEYGgKIIhqlKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSDLEV--EYEE 192
Cdd:PLN02882 124 TRYSKEWE-KTV---TRTGRWIDFENDYKTMDPKFMESVWWVFKQLFEKGLVYKGFKVMPYSTACKTPLSNFEAglNYKD 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 193 LEGKLTYIKYPLTppipplargGDNKRGYITVATTRPETMLGDTAVAVNPE------------------DSR-------- 246
Cdd:PLN02882 200 VSDPAVMVSFPIV---------GDPDNASFVAWTTTPWTLPSNLALCVNPNftyvkvrnkytgkvyivaESRlsalptak 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 247 ---------------YQ---KFIGKTIN-----------LPLTDRKILIISDHAVDPSFGTGAVKVTPAHDFNDE--AIA 295
Cdd:PLN02882 271 pkskkgskpenaaegYEvlaKVPGSSLVgkkyeplfdyfSEFSDTAFRVVADDYVTDDSGTGVVHCAPAFGEDDYrvCLA 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 296 KKQIPPLEFITV-IGADGLMTVNAGNrYAGLDRYECRKLVIKDLKVLNLLEKEELYKYAVGHCYRCKTitePL---STPQ 371
Cdd:PLN02882 351 NGIIEKGGNLPVpVDDDGCFTEKVTD-FSGRYVKDADKDIIAAIKAKGRLVKSGSITHSYPFCWRSDT---PLiyrAVPS 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 372 WYVNVQSIaKDaiRVVKEGKiniipKT-W------ENTYFAWMEDIKDWCISRQIWWGHRIPVWYCQKMQN-------AK 437
Cdd:PLN02882 427 WFVKVEEI-KD--RLLENNK-----QTyWvpdyvkEKRFHNWLENARDWAVSRSRFWGTPLPIWISDDGEEvvvigsiAE 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 438 CKMQNGVIVS---RD-VPQV-CPYCSSEE---LIQDEDVLDTWFSSALWPFSTLGWP-DNTDDLKTFYPTSVLVTGFDII 508
Cdd:PLN02882 499 LEKLSGVKVTdlhRHfIDHItIPSSRGPEfgvLRRVDDVFDCWFESGSMPYAYIHYPfENKELFEKNFPADFVAEGLDQT 578
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 509 FFWVARMIMMGLKFMGDVPFRDVYIHALVRDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLA-AFTAQGRDIKFSEKR 587
Cdd:PLN02882 579 RGWFYTLMVLSTALFDKPAFKNLICNGLVLAEDGKKMSKSLKNYPDPNEVIDKYGADALRLYLInSPVVRAEPLRFKEEG 658
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 588 VEGYRHFVNKLW-NAARFIMMNTnpptpplekggkggfEKEGVERITH-TPHDLAS---------KWILSRLAAIADDIN 656
Cdd:PLN02882 659 VFGVVKDVFLPWyNAYRFLVQNA---------------KRLEVEGGAPfVPLDLAKlqnsanvldRWINSATQSLVKFVR 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 657 RALEEYRFNDAASSIYQFVwHEFCDWYLEmakseinpptqpsLSRGEGKGGDGNSEPRTPNSqtgvrwCLLHTLDTSLRL 736
Cdd:PLN02882 724 EEMGAYRLYTVVPYLVKFI-DNLTNIYVR-------------FNRKRLKGRTGEEDCRTALS------TLYNVLLTSCKV 783
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278345029 737 LHPFMPFVTEEIWQTIKIQHSAIKESIMVSDYPKSL-----PRDYQAEEDMSYIIEAVMGIR 793
Cdd:PLN02882 784 MAPFTPFFTEVLYQNLRKVLPGSEESIHYCSFPQVDegeldERIEQSVSRMQTVIELARNIR 845
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
1-677 |
1.93e-28 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 123.39 E-value: 1.93e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 1 MLEKGYNPQGIEERWYEYWVSKGYFKPdPDL----KGSFYSL-VIPPPNITGsLHMGHALNTVLQDILSRWKRMSGYKVL 75
Cdd:PLN02563 75 AAKRAYPFHEIEPKWQRYWEENRTFRT-PDDvdtsKPKFYVLdMFPYPSGAG-LHVGHPEGYTATDILARYKRMQGYNVL 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 76 WLPGTDHAGI-ATQNVVEkqlasTGLD-RDKLGRNafIERVWKwkaeyggkiihQLKRLGASCDWSRERFTLDDGLSKAV 153
Cdd:PLN02563 153 HPMGWDAFGLpAEQYAIE-----TGTHpKITTLKN--IARFRS-----------QLKSLGFSYDWDREISTTEPEYYKWT 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 154 REVFVRLYEEGLIYRDNRLINWCPRCNTALSDLEV-------------------------EY-EELEGKLTYIKYPLTPP 207
Cdd:PLN02563 215 QWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVvdglsergghpvirkpmrqwmlkitAYaDRLLEDLDDLDWPESIK 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 208 ----------------IPPLARGGDNKRGYITVATTRPETMLGDTAVAVNPED----------------------SR--- 246
Cdd:PLN02563 295 emqrnwigrsegaeldFSVLDGEGKERDEKITVYTTRPDTLFGATYLVVAPEHpllsslttaeqkeaveeyvdaaSRksd 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 247 -----YQK-----FIGKTINLPLTDRKILI-ISDHaVDPSFGTGAVKVTPAHDFNDEAIAKKQIPPLEFItVIGADGlmt 315
Cdd:PLN02563 375 lerteLQKektgvFTGSYAINPATGEAIPIwVADY-VLGSYGTGAIMAVPAHDTRDFEFAQKFDLPIKWV-VKPADG--- 449
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 316 vnagnryagldryecrklvikdlkvlNLLEKEElykyavghCYRCKTITEPLSTPQWYVNVQSIAKDAIRVVK--EGKIN 393
Cdd:PLN02563 450 --------------------------NEDDAEK--------AYTGEGVIVNSSSSGLDINGLSSKEAAKKVIEwlEETGN 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 394 IIPKTwenTYfawmeDIKDWCISRQIWWGHRIPVWYCQKMQNAKckmqngVIVSRDVP-------QVCPYCSSEE-LIQD 465
Cdd:PLN02563 496 GKKKV---NY-----KLRDWLFARQRYWGEPIPVVFLEDSGEPV------PVPESDLPltlpeldDFTPTGTGEPpLAKA 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 466 EDVLDTWFSSALWPF----STL-GW------------PDNTDDL------KTFYPTSVLVTG-----FDIIF--FW---- 511
Cdd:PLN02563 562 VSWVNTVDPSSGKPArretNTMpQWagscwyylrfmdPKNSNALvdkekeKYWMPVDLYVGGaehavLHLLYarFWhkvl 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 512 -----------VARMIMMGLkFMGDV---PFRDV---YIHALVRDLKGQ------------------------------- 543
Cdd:PLN02563 642 ydigvvstkepFQCLVNQGM-ILGEVeytAFKDSdgeYVSADTADRLGElqqekipeekviksgdsfvlkddpsirliar 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 544 --KMSKSKGNVVDPLIMIDRYGTDAFRFtLAAFTAQGRDIK-FSEKRVEGYRHFVNKLWnaaRFIMmntnppTPPLEKGG 620
Cdd:PLN02563 721 ahKMSKSRGNVVNPDDVVSEYGADSLRL-YEMFMGPLRDSKtWSTSGVEGVHRFLGRTW---RLVV------GAPLPDGS 790
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*...
gi 1278345029 621 KGGFEKegverITHTPHDLASKWILSR-LAAIADDInralEEYRFNDAASSIYQFVWH 677
Cdd:PLN02563 791 FRDGTV-----VTDEEPSLEQLRLLHKcIAKVTEEI----ESTRFNTAISAMMEFTNA 839
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
40-750 |
5.01e-21 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 98.26 E-value: 5.01e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 40 IPPPNitGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTD-HaGiatQNVVEKqlAstgldrDKLGRN--AFIERVWK 116
Cdd:COG0143 9 IPYAN--GPPHIGHLYTYIPADILARYQRLRGHDVLFVTGTDeH-G---TKIELA--A------EKEGITpqELVDRIHA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 117 wkaeyggkiIHQ--LKRLGASCD-WSRerfTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSDleveyeel 193
Cdd:COG0143 75 ---------EFKelFEKLGISFDnFIR---TTSPEHKELVQEIFQRLYDNGDIYKGEYEGWYCPECERFLPD-------- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 194 egklTYIKypltppipplarggdnkrgyitvattrpetmlgDTAVAVNPEDSRYQKFIGKTINLPLTDRKILIISDHavd 273
Cdd:COG0143 135 ----RYVE---------------------------------GTCPKCGAEDAYGDQCENCGATLEPTELINPRSAIS--- 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 274 psfGTGAVKVTPAHDFNDeaiakkqipplefitvigadglmtvnagnryagLDRYEcrklvikdlkvlnllekEELYKYa 353
Cdd:COG0143 175 ---GAPPELREEEHYFFR---------------------------------LSKYQ-----------------DRLLEW- 200
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 354 vghcYRcktiteplSTPQWYVNVqsiAKDAIRVVKEGkiniipktwentyfawmedIKDWCISRQIWWGHRIP-----VW 428
Cdd:COG0143 201 ----IE--------ENPDIQPEV---RNEVLSWLKEG-------------------LQDLSISRDFDWGIPVPgdpgkVF 246
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 429 YCqkmqnakckmqngvivsrdvpqvcpycsseeliqdedvldtWFSsALWPF--STLGWPDNT---DDLKTFYP----TS 499
Cdd:COG0143 247 YV-----------------------------------------WFD-ALIGYisATKGYADDRglpEDFEKYWPapdtEL 284
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 500 VLVTGFDIIFF----WVArMIM-MGLKfmgdVPfRDVYIHALVrDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAF 574
Cdd:COG0143 285 VHFIGKDIIRFhaiiWPA-MLMaAGLP----LP-KKVFAHGFL-TVEGEKMSKSRGNVIDPDDLLDRYGPDALRYYLLRE 357
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 575 TAQGRDIKFSEK----RVEGyrHFVNKLWN----AARFIMMNTN--PPTPplekggkggfekegverithTPHDLASKWI 644
Cdd:COG0143 358 VPFGQDGDFSWEdfvaRVNS--DLANDLGNlasrTLSMIHKYFDgkVPEP--------------------GELTEADEEL 415
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 645 LSRLAAIADDINRALEEYRFNDAASSIYQFVwhefcdwylemakseinpptqpslsrgegkgGDGN-----SEP----RT 715
Cdd:COG0143 416 LAEAEAALEEVAEAMEAFEFRKALEEIMALA-------------------------------RAANkyideTAPwklaKD 464
|
730 740 750
....*....|....*....|....*....|....*....
gi 1278345029 716 PNsQTGVRWCLLHTLDtSLR----LLHPFMPFVTEEIWQ 750
Cdd:COG0143 465 ED-PERLATVLYTLLE-ALRilaiLLKPFLPETAEKILE 501
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
583-789 |
6.31e-20 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 88.38 E-value: 6.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 583 FSEKRV-EGYRHFVNKLWNAARFIMMNTNpptpplekggkggfekegVERITHTPHDLAS-------KWILSRLAAIADD 654
Cdd:cd07961 1 FSEKGVrEVVRKVLLPLWNAYRFFVTYAN------------------LDGFDPGKDDDAVaslnvldRWILSRLNSLIKE 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 655 INRALEEYRFNDAASSIYQFVwHEFCDWYLEmakseinpptqpsLSRGEGKGGDGNSEprtpnsQTGVRWCLLHTLDTSL 734
Cdd:cd07961 63 VTEEMEAYDLYTAVRALLEFI-DELTNWYIR-------------RNRKRFWGEEGDDD------KLAAYATLYEVLLTLS 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1278345029 735 RLLHPFMPFVTEEIWQTIKIQHSAIKESIMVSDYPK--SLPRDYQAEEDMSYIIEAV 789
Cdd:cd07961 123 RLMAPFTPFITEEIYQNLRRELGDAPESVHLLDWPEvdESLIDEELEEAMELVREIV 179
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
35-750 |
1.17e-18 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 90.33 E-value: 1.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 35 FYsLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTD-H----------AGIATQNVVEKQLAStgldrd 103
Cdd:PRK11893 3 FY-ITTPIYYPNGKPHIGHAYTTLAADVLARFKRLRGYDVFFLTGTDeHgqkiqrkaeeAGISPQELADRNSAA------ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 104 klgrnafIERVWKwkaeyggkiihqlkRLGASCD-WSRerfTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCnta 182
Cdd:PRK11893 76 -------FKRLWE--------------ALNISYDdFIR---TTDPRHKEAVQEIFQRLLANGDIYLGKYEGWYCVRC--- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 183 lsdlEVEYEELEgkltyikypLTPPIPPLARGGDNkrgyitvattrpetmlgdtaVAVNPED------SRYQKFIGKTIn 256
Cdd:PRK11893 129 ----EEFYTESE---------LIEDGYRCPPTGAP--------------------VEWVEEEsyffrlSKYQDKLLELY- 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 257 lpltdrkiliisdhAVDPSFgtgavkvtpahdfndeaiakkqIPPlefitvigadglmtvnagnryagldryecrklvik 336
Cdd:PRK11893 175 --------------EANPDF----------------------IQP----------------------------------- 183
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 337 dlkvlnllekeelykyavghcyrcktiteplstpqwyvnvQSIAKDAIRVVKEGkiniipktwentyfawmedIKDWCIS 416
Cdd:PRK11893 184 ----------------------------------------ASRRNEVISFVKSG-------------------LKDLSIS 204
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 417 RQ-IWWGhrIPVwycqkmqnakckmqngvivsrdvpqvcPycsseeliQDED-VLDTWFSsALWPF-STLGWPDN----T 489
Cdd:PRK11893 205 RTnFDWG--IPV---------------------------P--------GDPKhVIYVWFD-ALTNYlTALGYPDDeellA 246
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 490 DDLKTFYPTSVLVTGFDIIFF----WVARMIMMGLKfmgdVPFRdVYIHA-LVRDlkGQKMSKSKGNVVDPLIMIDRYGT 564
Cdd:PRK11893 247 ELFNKYWPADVHLIGKDILRFhavyWPAFLMAAGLP----LPKR-VFAHGfLTLD--GEKMSKSLGNVIDPFDLVDEYGV 319
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 565 DAFRFTLAAFTAQGRDIKFSEKRVEGYR--HFVNKLWN-AARFIMM---NTNPPTPplekggkggfekegvERITHTPHD 638
Cdd:PRK11893 320 DAVRYFLLREIPFGQDGDFSREAFINRInaDLANDLGNlAQRTLSMiakNFDGKVP---------------EPGALTEAD 384
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 639 LAskwILSRLAAIADDINRALEEYRFNDAASSIYQFVwhEFCDWYLEmakseinpptqpslsrgegkggdgNSEPRTPNS 718
Cdd:PRK11893 385 EA---LLEAAAALLERVRAAMDNLAFDKALEAILALV--RAANKYID------------------------EQAPWSLAK 435
|
730 740 750
....*....|....*....|....*....|....*..
gi 1278345029 719 QTGVRWC-LLHTLDTSLR----LLHPFMPFVTEEIWQ 750
Cdd:PRK11893 436 TDPERLAtVLYTLLEVLRgiavLLQPVMPELAAKILD 472
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
35-176 |
1.93e-18 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 87.30 E-value: 1.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 35 FYSLVI-PPPNitGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVekqlastgldrDKLGRNAFier 113
Cdd:cd00812 2 FYILVMfPYPS--GALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFDAFGLPAENAA-----------IKIGRDPE--- 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278345029 114 vwKWKAEYGGKIIHQLKRLGASCDWSRERFTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWC 176
Cdd:cd00812 66 --DWTEYNIKKMKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWC 126
|
|
| metG |
TIGR00398 |
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ... |
40-598 |
6.56e-18 |
|
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ligase. This model appears to recognize the methionyl-tRNA synthetase of every species, including eukaryotic cytosolic and mitochondrial forms. The UPGMA difference tree calculated after search and alignment according to this model shows an unusual deep split between two families of MetG. One family contains forms from the Archaea, yeast cytosol, spirochetes, and E. coli, among others. The other family includes forms from yeast mitochondrion, Synechocystis sp., Bacillus subtilis, the Mycoplasmas, Aquifex aeolicus, and Helicobacter pylori. The E. coli enzyme is homodimeric, although monomeric forms can be prepared that are fully active. Activity of this enzyme in bacteria includes aminoacylation of fMet-tRNA with Met; subsequent formylation of the Met to fMet is catalyzed by a separate enzyme. Note that the protein from Aquifex aeolicus is split into an alpha (large) and beta (small) subunit; this model does not include the C-terminal region corresponding to the beta chain. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273058 [Multi-domain] Cd Length: 530 Bit Score: 88.20 E-value: 6.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 40 IPPPNitGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVEKQlastGLDRDKlgrnaFIERvwkwka 119
Cdd:TIGR00398 7 LPYAN--GKPHLGHAYTTILADVYARYKRLRGYEVLFVCGTDEHGTKIELKAEQE----GLTPKE-----LVDK------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 120 eYGGKIIHQLKRLGASCDwsreRF--TLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSDLEVeyeelEGKL 197
Cdd:TIGR00398 70 -YHEEFKDDWKWLNISFD----RFirTTDEEHKEIVQKIFQKLKENGYIYEKEIKQLYCPECEMFLPDRYV-----EGTC 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 198 TYIKYpltppipplarggdnkrgyitvattrpETMLGDtavavnpedsryqkfigktinlpltdrkiliisdhavdpsfg 277
Cdd:TIGR00398 140 PKCGS---------------------------EDARGD------------------------------------------ 150
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 278 tgavkvtpahdfNDEAIAKKQiPPLEFITvigadglmtvnagnryagldryecrklvikdlkvlnllekeelykyavGHC 357
Cdd:TIGR00398 151 ------------HCEVCGRHL-EPTELIN------------------------------------------------PRC 169
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 358 YRCKTITEPLSTPQWYVNVQSIAKDAIRVVkegKINIIPKTW----ENTYFAWMED-IKDWCISRQI-WWGHRIPvwycq 431
Cdd:TIGR00398 170 KICGAKPELRDSEHYFFRLSAFEKELEEWI---RKNPESGSPasnvKNKAQNWLKGgLKDLAITRDLvYWGIPVP----- 241
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 432 kmqNAKCKMqngVIVSRDVPqvCPYCSS-EELIQDEDVLDTWfssalwpfstlgWPDNTDdlktfyPTSVLVTGFDIIFF 510
Cdd:TIGR00398 242 ---NDPNKV---VYVWFDAL--IGYISSlGILSGDTEDWKKW------------WNNDED------AELIHFIGKDIVRF 295
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 511 ----WVARMIMMGLKFmgdvpFRDVYIHALVRDlKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAFTAQGRDIKFSEK 586
Cdd:TIGR00398 296 htiyWPAMLMGLGLPL-----PTQVFSHGYLTV-EGGKMSKSLGNVVDPSDLLARFGADILRYYLLKERPLGKDGDFSWE 369
|
570
....*....|..
gi 1278345029 587 RvegyrhFVNKL 598
Cdd:TIGR00398 370 D------FVERV 375
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
481-816 |
7.67e-17 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 85.24 E-value: 7.67e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 481 STLGWPDNTDDL-KTFYPTSVLVTGFDIIFF----WVArMIMM-GLKfmgdvPFRDVYIHA-LVRdlKGQKMSKSKGNVV 553
Cdd:PRK12267 237 TALGYGSDDDELfKKFWPADVHLVGKDILRFhaiyWPI-MLMAlGLP-----LPKKVFAHGwWLM--KDGKMSKSKGNVV 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 554 DPLIMIDRYGTDAFRFTL---AAFtaqGRDIKFSEKRvegyrhFVNKLwNA----------ARFIMM-----NTNPPTPP 615
Cdd:PRK12267 309 DPEELVDRYGLDALRYYLlreVPF---GSDGDFSPEA------LVERI-NSdlandlgnllNRTVAMinkyfDGEIPAPG 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 616 lekggkggfekegveriTHTPHDlasKWILSRLAAIADDINRALEEYRFNDAASSIYQFVwhefcdwylemakSEIN--- 692
Cdd:PRK12267 379 -----------------NVTEFD---EELIALAEETLKNYEELMEELQFSRALEEVWKLI-------------SRANkyi 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 693 PPTQP-SLSRGEGKGGDGNSeprtpnsqtgvrwcLLHTLDTSLR----LLHPFMPFVTEEIWQTIKIQHS---------- 757
Cdd:PRK12267 426 DETAPwVLAKDEGKKERLAT--------------VMYHLAESLRkvavLLSPFMPETSKKIFEQLGLEEEltswesllew 491
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1278345029 758 -AIKESIMVSDYPKSLPR-DYQAEEDmsYIIEAVMGIRTIRGELNISPSLKLNVSIKTFSQ 816
Cdd:PRK12267 492 gGLPAGTKVAKGEPLFPRiDVEEEIA--YIKEQMEGSAPKEPEEKEKKPEKPEITIDDFDK 550
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
588-794 |
1.87e-16 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 78.34 E-value: 1.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 588 VEGYRhfvnKLWNAARFIMMNTNPPTPplekggkggfekegvERITHTPHDLAS--KWILSRLAAIADDINRALEEYRFN 665
Cdd:cd07960 10 AEAYR----KIRNTFRFLLGNLNDFDP---------------AKDAVPYEELLEldRYALHRLNELIKEVREAYENYEFH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 666 DAASSIYQFVWHEFCDWYLEMAKSE--INPPtqpslsrgegkggdgNSEPRTpNSQTgvrwCLLHTLDTSLRLLHPFMPF 743
Cdd:cd07960 71 KVYQALNNFCTVDLSAFYLDIIKDRlyCDAK---------------DSLERR-SAQT----VLYHILDALLKLLAPILPF 130
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1278345029 744 VTEEIWQTIKiqHSAIKESIMVSDYPKsLPRDYQAEEDMSyIIEAVMGIRT 794
Cdd:cd07960 131 TAEEVWEHLP--GEKKEESVFLEDWPE-LPEEWKDEELEE-KWEKLLALRD 177
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
40-598 |
3.50e-16 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 81.57 E-value: 3.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 40 IPPPNitGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVEKQlastGLDRDKLGrnafiervwkwkA 119
Cdd:pfam09334 7 LPYAN--GPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAEKE----GITPEELV------------D 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 120 EYGGKIIHQLKRLGASCD-WSRerfTLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSDleveyEELEGKLT 198
Cdd:pfam09334 69 RYHEIHREDFKKFNISFDdYGR---TTSERHHELVQEFFLKLYENGYIYEKEIEQFYCPSDERFLPD-----RYVEGTCP 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 199 YIKYpltppipPLARgGDNkrgyitvattrpetmLGDTAVAVNPEDsryqkfigktinlpLTDRKILIisdhavdpSFGT 278
Cdd:pfam09334 141 HCGS-------EDAR-GDQ---------------CENCGRHLEPTE--------------LINPKCVI--------CGTT 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 279 GAVKVTpAHDFNDeaiakkqipplefitvigadglmtvnagnryagLDRYEcrklvikdlkvlnllekEELYKYAVGHcy 358
Cdd:pfam09334 176 PEVKET-EHYFFD---------------------------------LSKFQ-----------------DKLREWIEEN-- 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 359 rcktiteplsTPQWYVNVQSIAKDAIRvvkegkiniipktwentyfawmEDIKDWCISRQIWWGHRIP--------VWYc 430
Cdd:pfam09334 203 ----------NPEWPENVKNMVLEWLK----------------------EGLKDRAISRDLDWGIPVPgaegkvfyVWL- 249
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 431 qkmqnakckmqngvivsrDVPqvCPY-CSSEELIQDEDVLDTWfssalwpfstlgWPDNTDdlktfyPTSVLVTGFDIIF 509
Cdd:pfam09334 250 ------------------DAP--IGYiSATKELSGNEEKWKEW------------WPNDPD------TELVHFIGKDIIY 291
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 510 F----WVArmIMMGlkfmGDVPFRD-VYIHALVrDLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAFTAQGRDIKFS 584
Cdd:pfam09334 292 FhtifWPA--MLLG----AGYRLPTtVFAHGYL-TYEGGKMSKSRGNVVWPSEALDRFPPDALRYYLARNRPETKDTDFS 364
|
570
....*....|....
gi 1278345029 585 EkrvegyRHFVNKL 598
Cdd:pfam09334 365 W------EDFVERV 372
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
40-192 |
1.60e-13 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 72.56 E-value: 1.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 40 IPPPNitGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGIATQNVVEKQlastGLDRDKLG--RNAFIERVWKW 117
Cdd:cd00814 8 LPYVN--GVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAEEE----GVTPQELCdkYHEIFKDLFKW 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278345029 118 kaeyggkiihqlkrLGASCDwsreRF--TLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCNTALSdlEVEYEE 192
Cdd:cd00814 82 --------------LNISFD----YFirTTSPRHKEIVQEFFKKLYENGYIYEGEYEGLYCVSCERFLP--EWREEE 138
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
343-583 |
1.66e-13 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 72.56 E-value: 1.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 343 LLEKEELYK--YAVGHCYRCKT-ITEPLSTPQWYVNVQSIAKDAIRVVKEGKINIIPKTWENTYFAWMED-IKDWCISRQ 418
Cdd:cd00814 108 LYENGYIYEgeYEGLYCVSCERfLPEWREEEHYFFRLSKFQDRLLEWLEKNPDFIWPENARNEVLSWLKEgLKDLSITRD 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 419 IW-WGHRIPvwycqkmqnakcKMQNGVI-VSRDVPqvCPYCSSEELIQDEDVLDTWFSSalwpfstlGWPDNtddlktfy 496
Cdd:cd00814 188 LFdWGIPVP------------LDPGKVIyVWFDAL--IGYISATGYYNEEWGNSWWWKD--------GWPEL-------- 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 497 ptsVLVTGFDIIFF----WVArmIMMGLKFmgdVPFRDVYIHALVRdLKGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLA 572
Cdd:cd00814 238 ---VHFIGKDIIRFhaiyWPA--MLLGAGL---PLPTRIVAHGYLT-VEGKKMSKSRGNVVDPDDLLERYGADALRYYLL 308
|
250
....*....|.
gi 1278345029 573 AFTAQGRDIKF 583
Cdd:cd00814 309 RERPEGKDSDF 319
|
|
| Val_tRNA-synt_C |
pfam10458 |
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA ... |
869-934 |
8.91e-11 |
|
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA synthetases.
Pssm-ID: 431296 [Multi-domain] Cd Length: 66 Bit Score: 58.43 E-value: 8.91e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278345029 869 NITAEVDRLKKEEAKVDVSIVSLNRKLFNEDFLQRAPREIIDKEKAKYEELIIIKKRILESIKMLK 934
Cdd:pfam10458 1 DVEKERARLEKELAKLQKEIERVQGKLANPGFVAKAPAEVVEEEKAKLAELEEQAEKLRERLSKLG 66
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
630-752 |
1.03e-08 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 54.13 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 630 ERITHTPHDlasKWILSRLAAIADDINRALEEYRFNDAASSIYQFVWHEFcDWYLEMAKSEINpptqpslsrgegkggdg 709
Cdd:cd07959 29 ELEELTFID---RWLLSRLNRLIKETTEAYENMQFREALKEGLYELQNDL-DWYRERGGAGMN----------------- 87
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1278345029 710 nseprtpnsqtgvRWCLLHTLDTSLRLLHPFMPFVTEEIWQTI 752
Cdd:cd07959 88 -------------KDLLRRFIEVWTRLLAPFAPHLAEEIWHEL 117
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
465-587 |
8.17e-07 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 52.79 E-value: 8.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 465 DEDVLDTWFSSALWPFSTLGWPDNTDDLKTF----YPTSVLVTGFDIIFF----WVARMIMMGLkfmgDVPfRDVYIHA- 535
Cdd:PLN02224 285 DKQTIYVWFDALLGYISALTEDNKQQNLETAvsfgWPASLHLIGKDILRFhavyWPAMLMSAGL----ELP-KMVFGHGf 359
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1278345029 536 LVRDlkGQKMSKSKGNVVDPLIMIDRYGTDAFRFTLAAFTAQGRDIKFSEKR 587
Cdd:PLN02224 360 LTKD--GMKMGKSLGNTLEPFELVQKFGPDAVRYFFLREVEFGNDGDYSEDR 409
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
32-217 |
4.89e-06 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 50.48 E-value: 4.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 32 KGSFYSLVIPPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGiatqnvvEKQLASTGLDrdklGRNAfi 111
Cdd:PLN02224 67 EADTFVLTTPLYYVNAPPHMGSAYTTIAADSIARFQRLLGKKVIFITGTDEHG-------EKIATSAAAN----GRNP-- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 112 ervwkwkAEYGGKIIHQLKRLGASCDWSRERF--TLDDGLSKAVREVFVRLYEEGLIYRDNRLINWCPRCntalSDLEVE 189
Cdd:PLN02224 134 -------PEHCDIISQSYRTLWKDLDIAYDKFirTTDPKHEAIVKEFYARVFANGDIYRADYEGLYCVNC----EEYKDE 202
|
170 180
....*....|....*....|....*...
gi 1278345029 190 YEELEGKLTYIKypltpPIPPLARGGDN 217
Cdd:PLN02224 203 KELLENNCCPVH-----QMPCVARKEDN 225
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
584-752 |
6.97e-06 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 46.06 E-value: 6.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 584 SEKRVEGYRHFVNKLWnaaRFIMMNTNPPTPPlEKGGKGGFEKEGVERITH-TphdlaskwilsrLAAIADDInralEEY 662
Cdd:cd07958 2 SDSGVEGAYRFLNRVW---RLVTELAEALAAP-AAAAELSEEDKELRRKLHkT------------IKKVTEDI----ERL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 663 RFNDAASSIYQFVwhefcdwylemakseiNpptqpSLSRGEGKGGDGNSEPRtpnsqtgvrwcllHTLDTSLRLLHPFMP 742
Cdd:cd07958 62 RFNTAIAALMELV----------------N-----ALYKYKKKDAQHAAVLR-------------EALETLVLLLAPFAP 107
|
170
....*....|
gi 1278345029 743 FVTEEIWQTI 752
Cdd:cd07958 108 HIAEELWEEL 117
|
|
| Anticodon_Ia_like |
cd07375 |
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ... |
585-688 |
1.13e-05 |
|
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.
Pssm-ID: 153408 [Multi-domain] Cd Length: 117 Bit Score: 45.57 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 585 EKRVEGYRHFVNKLWNAARFIMMNTNPPTPPLEKGGKGgfekegverithtphdLASKWILSRLAAIADDINRALEEYRF 664
Cdd:cd07375 1 EERLKQARAFLNRLYRLLSFFRKALGGTQPKWDNELLE----------------EADRELLARLQEFIKRTTNALEALDP 64
|
90 100
....*....|....*....|....
gi 1278345029 665 NDAASSIYQFVWHEfcDWYLEMAK 688
Cdd:cd07375 65 TTAVQELFKFTNEL--NWYLDELK 86
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
129-265 |
2.87e-05 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 48.14 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 129 LKRLGASCDWSRERFTLD-----DGLskaVREVFVRLYEEGLIYRDNRlinwcprcNTALSDLE----VEYEELEGK--- 196
Cdd:PLN02959 198 LKAFGLGCDWRRSFITTDvnpyyDAF---VRWQFRKLKKKGKIVKDKR--------YTIYSPLDgqpcADHDRASGEgvg 266
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278345029 197 ---LTYIKYPLTPPIPPLARGGDNKRGYITVATTRPETMLGDTAVAVNPeDSRYQKF-IGKTINLPLTDRKIL 265
Cdd:PLN02959 267 pqeYVLIKMEVLPPFPGKLKALEGKKVFLAAATLRPETMYGQTNCWVLP-DGKYGAYeINDTEVFILTARAAL 338
|
|
| ArgRS_core |
cd00671 |
catalytic core domain of arginyl-tRNA synthetases; Arginyl tRNA synthetase (ArgRS) catalytic ... |
43-75 |
8.06e-05 |
|
catalytic core domain of arginyl-tRNA synthetases; Arginyl tRNA synthetase (ArgRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. There are at least three subgroups of ArgRS. One type contains both characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. The second subtype lacks the KMSKS motif; however, it has a lysine N-terminal to the HIGH motif, which serves as the functional counterpart to the second lysine of the KMSKS motif. A third group, which is found primarily in archaea and a few bacteria, lacks both the KMSKS motif and the HIGH loop lysine.
Pssm-ID: 185675 [Multi-domain] Cd Length: 212 Bit Score: 44.86 E-value: 8.06e-05
10 20 30
....*....|....*....|....*....|...
gi 1278345029 43 PNITGSLHMGHALNTVLQDILSRWKRMSGYKVL 75
Cdd:cd00671 9 ANPTGPLHVGHLRNAIIGDSLARILEFLGYDVT 41
|
|
| ArgS |
COG0018 |
Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Arginyl-tRNA ... |
43-170 |
9.44e-05 |
|
Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Arginyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439789 [Multi-domain] Cd Length: 574 Bit Score: 46.29 E-value: 9.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 43 PNITGSLHMGHALNTVLQDILSRWKRMSGYKVL-------WlpGT--DHAGIATQN--------------------VVEK 93
Cdd:COG0018 125 ANPTKPLHVGHLRGAVIGDALARILEAAGYDVTrenyindA--GTqiGKLALSLERygeeeiepeskpdgylgdlyVKFH 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 94 QLASTGLDRDKLGRNAFIE---------RVWKW--KAEYGGkIIHQLKRLGASCD-WSRERFTLDDGlskAVREVFVRLY 161
Cdd:COG0018 203 KEYEEDPELEDIARELLAKlepgdeealELWKKavDWSLEE-IKEDLKRLGVEFDvWFSESSLYDSG---AVEEVVEELK 278
|
....*....
gi 1278345029 162 EEGLIYRDN 170
Cdd:COG0018 279 EKGLLYESD 287
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
47-185 |
1.15e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 45.91 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 47 GSLHMGHALnTVLQ-DILSRWKRMSGYKVLWLPGTDHAGIATQnvvekqlastgLDRDKLGRN--AFIERVWKwkaeygg 123
Cdd:PRK00133 15 GPIHLGHLV-EYIQaDIWVRYQRMRGHEVLFVCADDAHGTPIM-----------LKAEKEGITpeELIARYHA------- 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278345029 124 kiIHQ--LKRLGASCD-WSRerfTLDDGLSKAVREVFVRLYEEGLIYRdnRLIN--WCPRCNTALSD 185
Cdd:PRK00133 76 --EHKrdFAGFGISFDnYGS---THSEENRELAQEIYLKLKENGYIYE--KTIEqlYDPEKGMFLPD 135
|
|
| class_I_aaRS_core |
cd00802 |
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA ... |
41-139 |
1.39e-04 |
|
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA synthetase (aaRS) catalytic core domain. These enzymes are mostly monomers which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173901 [Multi-domain] Cd Length: 143 Bit Score: 42.85 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 41 PPPNITGSLHMGHALNTVLQDILSRWKRMSGYKVLWLPGTDHAGiatqNVVEKQLASTGLDRdKLGRNAFIERVwkwKAE 120
Cdd:cd00802 4 SGITPNGYLHIGHLRTIVTFDFLAQAYRKLGYKVRCIALIDDAG----GLIGDPANKKGENA-KAFVERWIERI---KED 75
|
90 100
....*....|....*....|..
gi 1278345029 121 YGGKIIH---QLKRLGASCDWS 139
Cdd:cd00802 76 VEYMFLQaadFLLLYETECDIH 97
|
|
| argS |
PRK01611 |
arginyl-tRNA synthetase; Reviewed |
43-169 |
1.63e-04 |
|
arginyl-tRNA synthetase; Reviewed
Pssm-ID: 234964 [Multi-domain] Cd Length: 507 Bit Score: 45.15 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 43 PNITGSLHMGHALNTVLQDILSRWKRMSGYKVLwlpgtdhagiaTQNVVEkqlastglDR----DKLGRNafIERVWKWK 118
Cdd:PRK01611 120 ANPTGPLHVGHLRSAVIGDALARILEFAGYDVT-----------REYYVN--------DAgtqiGMLIAS--LELLWRKA 178
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1278345029 119 AEYGGKIIHQ-LKRLGASCD-WSRERFTLDDGLskaVREVFVRLYEEGLIYRD 169
Cdd:PRK01611 179 VDISLDEIKEdLDRLGVHFDvWFSESELYYNGK---VDEVVEDLKEKGLLYVE 228
|
|
| PRK12418 |
PRK12418 |
cysteinyl-tRNA synthetase; Provisional |
524-553 |
2.93e-03 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 183518 [Multi-domain] Cd Length: 384 Bit Score: 41.07 E-value: 2.93e-03
10 20 30
....*....|....*....|....*....|
gi 1278345029 524 GDVPFRDVYIHALVRDLKGQKMSKSKGNVV 553
Cdd:PRK12418 241 GERRFARHYVHAGMIGLDGEKMSKSRGNLV 270
|
|
| argS |
TIGR00456 |
arginyl-tRNA synthetase; This model recognizes arginyl-tRNA synthetase in every completed ... |
43-176 |
3.24e-03 |
|
arginyl-tRNA synthetase; This model recognizes arginyl-tRNA synthetase in every completed genome to date. An interesting feature of the alignment of all arginyl-tRNA synthetases is a fairly deep split between two families. One family includes archaeal, eukaryotic and organellar, spirochete, E. coli, and Synechocystis sp. The second, sharing a deletion of about 25 residues in the central region relative to the first, includes Bacillus subtilis, Aquifex aeolicus, the Mycoplasmas and Mycobacteria, and the Gram-negative bacterium Helicobacter pylori. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273085 [Multi-domain] Cd Length: 563 Bit Score: 41.17 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 43 PNITGSLHMGHALNTVLQDILSRWKRMSGYKVLwlpgtdhagiaTQNVVE---KQLASTGLDRDKLGRNAFIERVWKWKA 119
Cdd:TIGR00456 121 ANPAGPLHVGHLRNAIIGDSLARILEFLGYDVI-----------REYYVNdwgRQFGLLALGVEKFGNEALNIAVKKPDH 189
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278345029 120 EYGGKIIHQLKRLGAscdwsrerftlDDGLSKAVREVFVRlYEEGLIYRD---NRLINWC 176
Cdd:TIGR00456 190 GLEGFYVEINKRLEE-----------NEELEEEARELFVK-LESGDEETIklwKRLVEYS 237
|
|
| |
