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Conserved domains on  [gi|1278639224|gb|PJB46825|]
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molybdate ABC transporter permease subunit [Comamonadaceae bacterium CG_4_9_14_3_um_filter_60_33]

Protein Classification

molybdate ABC transporter permease subunit( domain architecture ID 10790565)

molybdate ABC transporter permease subunit is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system involved in the transport of molybdenum

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020|GO:0015098|GO:0015689
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 7-224 9.02e-88

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


:

Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 258.83  E-value: 9.02e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   7 TPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERL 86
Cdd:COG4149     2 SPEDWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVTLPLVLPPTVLGFYLLLLFGRNGPLGQLLEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  87 GLPHLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGE 166
Cdd:COG4149    82 FGISLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGE 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1278639224 167 FGVIAMLGGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:COG4149   162 FGATLMFAGNIPGKTQTLPLAIYDAVEAGDYAAAHALSLILLAISFVVLLLLNLLNRR 219
 
Name Accession Description Interval E-value
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 7-224 9.02e-88

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 258.83  E-value: 9.02e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   7 TPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERL 86
Cdd:COG4149     2 SPEDWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVTLPLVLPPTVLGFYLLLLFGRNGPLGQLLEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  87 GLPHLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGE 166
Cdd:COG4149    82 FGISLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGE 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1278639224 167 FGVIAMLGGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:COG4149   162 FGATLMFAGNIPGKTQTLPLAIYDAVEAGDYAAAHALSLILLAISFVVLLLLNLLNRR 219
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 15-224 1.52e-64

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 199.39  E-value: 1.52e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  15 WLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLPhLAFS 94
Cdd:TIGR02141   1 WLSLKVAVIATLLLLPLGIPVAWLLARSRFRGKPLLEVLVTLPLVLPPTVLGFYLLIAFGPNGPIGKLLELFGIS-LVFT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  95 FWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLG 174
Cdd:TIGR02141  80 FTGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLSFARALGEFGATLMFA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1278639224 175 GSIAGETRVVSIAIYDYTQAlNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:TIGR02141 160 GNIPGETQTIPLAIYDAVES-DYELAHQLSLVLLAISLIVLLLVELLNKR 208
modB PRK09421
molybdate ABC transporter permease subunit;
5-225 4.00e-40

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 137.36  E-value: 4.00e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   5 GITPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARS---GSRLVNSvaaLVALPLVLPPTVIGFYLLIVLGPQGAVGG 81
Cdd:PRK09421    2 ILSDPEWQAVLLSLKVSSVAVLFSLPFGILVAWLLARCrfpGKSLLDS---LLHLPLVLPPVVTGYLLLISMGRRGFIGQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  82 TL-ERLGLPhLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITF 160
Cdd:PRK09421   79 WLyEWFGIS-FAFSWRGAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAF 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278639224 161 AHTVGEFGVIAMLGGSIAGETRVVSIAIYDYTQALN-YGAAHRLSAILLGFSFLTLMLFYAINQRV 225
Cdd:PRK09421  158 ARSLGEFGATITFVSNIPGETQTIPSAMYTLIQTPGgESAAARLCIISIAIALASLLLSEWLARRS 223
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 14-212 1.66e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 69.23  E-value: 1.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  14 IWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQgavggtlerLGLPHLAF 93
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVL---------LGWGILPG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  94 SFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAML 173
Cdd:cd06261    72 LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFL 151

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1278639224 174 GGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSF 212
Cdd:cd06261   152 GGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 34-208 9.09e-10

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 56.01  E-value: 9.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  34 PLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAvggtlerLGLPHLAFSFWGILVGSVIYSLPFAVQP 113
Cdd:NF038017   18 PLGALLALRRFPGRRLVISLLNTLMGLPPVVVGLIVYLLLSRSGP-------LGFLGLLYTPTAMIIAQAVLALPIVAGL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 114 LREAFGAIDTRLLDAAATMRAGALDRFFSVVLPlSRSGILTAVVITFAHTVGEFGVIAMLGGSIAGETRVVSIAIYDYTQ 193
Cdd:NF038017   91 TLAAVQGLDPELRLQILSLGATRWQALWTLLKE-ARFALLAAVLAGFGRAISEVGAVMMVGGNIRGYTRVLTTAIVLETS 169

                         170
                  ....*....|....*
gi 1278639224 194 ALNYGAAHRLSAILL 208
Cdd:NF038017  170 KGNFDLALALGIILL 184
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 34-225 3.24e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.83  E-value: 3.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  34 PLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGgtlerlglphlaFSFWGILVGSVIYSLPFAVQP 113
Cdd:pfam00528   3 PLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILG------------HGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 114 LREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSIA-GETRVVSIAIYDYT 192
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGlGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1278639224 193 QALNYGAAhrLSAILLGFSFLTLMLFYAINQRV 225
Cdd:pfam00528 151 EIQGPVLA--AALILLLLNLLVDILQRLLDPRV 181
 
Name Accession Description Interval E-value
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 7-224 9.02e-88

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 258.83  E-value: 9.02e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   7 TPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERL 86
Cdd:COG4149     2 SPEDWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVTLPLVLPPTVLGFYLLLLFGRNGPLGQLLEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  87 GLPHLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGE 166
Cdd:COG4149    82 FGISLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGE 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1278639224 167 FGVIAMLGGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:COG4149   162 FGATLMFAGNIPGKTQTLPLAIYDAVEAGDYAAAHALSLILLAISFVVLLLLNLLNRR 219
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 15-224 1.52e-64

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 199.39  E-value: 1.52e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  15 WLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLPhLAFS 94
Cdd:TIGR02141   1 WLSLKVAVIATLLLLPLGIPVAWLLARSRFRGKPLLEVLVTLPLVLPPTVLGFYLLIAFGPNGPIGKLLELFGIS-LVFT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  95 FWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLG 174
Cdd:TIGR02141  80 FTGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLSFARALGEFGATLMFA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1278639224 175 GSIAGETRVVSIAIYDYTQAlNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:TIGR02141 160 GNIPGETQTIPLAIYDAVES-DYELAHQLSLVLLAISLIVLLLVELLNKR 208
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 11-224 4.64e-41

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 141.04  E-value: 4.64e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  11 WQAIWLTAKLAGLTTLILLLLSAPLAWWLARS---GSRLVNsvaALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLG 87
Cdd:COG0555    53 LAALKLSLGTALIAALINLVFGLPLAWVLVRYrfpGKRLVD---ALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLG 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  88 LpHLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEF 167
Cdd:COG0555   130 I-KVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEF 208

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1278639224 168 GVIAMLGGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:COG0555   209 GAVIFIAGNLPMKTEILPLLIYLKLEEGDYAGATAIALVLLLISFLLLLLINLLQRR 265
modB PRK09421
molybdate ABC transporter permease subunit;
5-225 4.00e-40

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 137.36  E-value: 4.00e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   5 GITPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARS---GSRLVNSvaaLVALPLVLPPTVIGFYLLIVLGPQGAVGG 81
Cdd:PRK09421    2 ILSDPEWQAVLLSLKVSSVAVLFSLPFGILVAWLLARCrfpGKSLLDS---LLHLPLVLPPVVTGYLLLISMGRRGFIGQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  82 TL-ERLGLPhLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITF 160
Cdd:PRK09421   79 WLyEWFGIS-FAFSWRGAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAF 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278639224 161 AHTVGEFGVIAMLGGSIAGETRVVSIAIYDYTQALN-YGAAHRLSAILLGFSFLTLMLFYAINQRV 225
Cdd:PRK09421  158 ARSLGEFGATITFVSNIPGETQTIPSAMYTLIQTPGgESAAARLCIISIAIALASLLLSEWLARRS 223
Mo_ABC_porter TIGR01581
NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively ...
 13-217 1.90e-32

NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively weak homology compared to its neighbor clades, the molybdate (TIGR02141) and sulfate (TIGR00969) porters. Neighbor-Joining, PAM-distance phylogenetic trees support the separation of the clades in this way. Included in this group is a gene designated NifC in Clostridium pasturianum. It would be reasonable to presume that NifC acts as a molybdate porter since the most common form of nitrogenase is a molybdoenzyme. Several other sequences falling within the scope of this model are annotated as molybdate porters and one, from Halobacterium, is annotated as a sulfate porter. There is presently no experimental evidence to support annotations with this degree of specificity.


Pssm-ID: 130643  Cd Length: 225  Bit Score: 117.50  E-value: 1.90e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  13 AIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLPhLA 92
Cdd:TIGR01581  22 ALRLSLATSLASLLLAVIIGIPTAYVLARVRFPLKKLLDTLLDLPMVLPPLVAGLALLLLFGRNGLLGPYLEAAGIQ-VI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  93 FSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAM 172
Cdd:TIGR01581 101 FSTLGVVLAQTFVASPYYVRVARSTFKSVDPRYEDVARSLGAGPLETFRKITLPMARPGLLAGLVLAWARALGEFGATLM 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1278639224 173 LGGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLML 217
Cdd:TIGR01581 181 FAGSIQGKTRTLPLAIYLNIQSDNIEAAVASALLLLVIAFLLLLV 225
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 11-224 7.65e-32

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 117.56  E-value: 7.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  11 WQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLP- 89
Cdd:COG1176    66 LKVLLRTLWIALLTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLId 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  90 ---HLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGE 166
Cdd:COG1176   146 eplRLLYTEFAVVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGA 225

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1278639224 167 FGVIAMLGGsiaGETRVVSIAIYD-YTQALNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:COG1176   226 FVTPALLGG---GKVLMIGNLIYQqFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRR 281
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
11-217 1.42e-26

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 106.78  E-value: 1.42e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  11 WQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTL-ERLGLP 89
Cdd:COG1178    53 WRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLrALFGLE 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  90 HLA-FSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFG 168
Cdd:COG1178   133 PPDiYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFG 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1278639224 169 VIAMLGGSIagetRVVSIAIYD-YTQALNYGAAHRLSAILLGFSFLTLML 217
Cdd:COG1178   213 TPLVLGGGY----TTLTTAIYQaWLGDFDLGAAAALALVLLLLVLLLLLL 258
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
3-224 5.80e-25

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 102.16  E-value: 5.80e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   3 FAGITPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGpqgavggt 82
Cdd:COG1178   329 FVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFN-------- 400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  83 leRLGLPHLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAH 162
Cdd:COG1178   401 --RPLPLLLYGTLAILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVT 478

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278639224 163 TVGEFGVIAMLGGSiagETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:COG1178   479 SMKELSATLLLRPP---GFETLAVLIYQLASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 11-224 2.17e-22

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 91.71  E-value: 2.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  11 WQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGavggtlerlglph 90
Cdd:COG1177    60 LDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALG------------- 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  91 LAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVI 170
Cdd:COG1177   127 LSGGLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVIT 206

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1278639224 171 AMLGGsiaGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQR 224
Cdd:COG1177   207 LFLAG---PGVTTLPVYIYSMIRRGISPEINALSTLLILLSLLLLLLAERLRRR 257
cysT CHL00187
sulfate transport protein; Provisional
 35-189 6.56e-19

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 81.98  E-value: 6.56e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  35 LAWWLAR---SGSRLVNsvaALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLpHLAFSFWGILVGSVIYSLPFAV 111
Cdd:CHL00187   78 IAWVLVRynfPGKRLLD---AAVDLPFALPTSVAGLTLATVYGDNGWIGHLLSHLGI-QIVFTKLGVLLAMIFVSFPFVV 153

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278639224 112 QPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSIAGETRVVSIAIY 189
Cdd:CHL00187  154 RTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEYGSIVIISSNIPFKDLVASVLIF 231
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
35-222 7.13e-16

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 74.41  E-value: 7.13e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  35 LAWWLAR---SGSRLVNsvaALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLpHLAFSFWGILVGSVIYSLPF-- 109
Cdd:PRK10971   81 MAWILTRyrfPGRTLLD---ALMDLPFALPTAVAGLTLASLFSVNGWYGEWLAKFDI-KVTYTWLGIAVAMAFTSIPFvv 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 110 -AVQPLREAFGAidtRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSIAGETRVVSIAI 188
Cdd:PRK10971  157 rTVQPVLEELGP---EYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIAGNIAWKTEVTSLMI 233

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1278639224 189 YDYTQALNYGAAHRLSAILLGFSfltLMLFYAIN 222
Cdd:PRK10971  234 FVRLQEFDYPAASAIASVILAAS---LLLLFSIN 264
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 2-232 1.96e-15

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 74.72  E-value: 1.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   2 NFAGI--TPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAV 79
Cdd:TIGR03262  42 NFAEYfaTPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  80 GGTLerlgLPHLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVIT 159
Cdd:TIGR03262 122 KGLL----GGFSIYGFWGIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVV 197

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278639224 160 FAHTVGEFGVIAMLGGSIagetRVVSIAIYDYT---QALNYGAAhrLSAILLGFSFLTLMLFYAINQRVMNPLKPR 232
Cdd:TIGR03262 198 FTLVITDFGVPKVIGGDY----NVLATDIYKQVigqQNFPMGAV--VGVLLLLPALLAFGIDRAIQRRQRAQLSSR 267
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 14-212 1.66e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 69.23  E-value: 1.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  14 IWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQgavggtlerLGLPHLAF 93
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVL---------LGWGILPG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  94 SFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAML 173
Cdd:cd06261    72 LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFL 151

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1278639224 174 GGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSF 212
Cdd:cd06261   152 GGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-227 4.63e-14

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 69.78  E-value: 4.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  11 WQAIWLTAKLAGLTTLILLLLSAPLAWWLARsGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQ-GAVGGTLERLGLP 89
Cdd:COG1175    75 WNALGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGALGLE 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  90 HLAF------SFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHT 163
Cdd:COG1175   154 PINWlgdpslALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGA 233

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278639224 164 VGEFGVI-AMLGGSIAGETRVVSIAIYDYT-QALNYGAAHRLSAILlgfsFLTLMLFYAINQRVMN 227
Cdd:COG1175   234 LQVFDLVyVLTGGGPGNSTTTLVLYIYQTAfQQFDFGYASAIAVVL----FLIILVLTLLQLRLLR 295
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
13-230 9.71e-14

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 68.62  E-value: 9.71e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  13 AIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLpHLA 92
Cdd:PRK11602   65 AIWLTVLIALIAVPVNLVFGILLAWLVTRFNFPGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNL-QLM 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  93 FSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAM 172
Cdd:PRK11602  144 FSWPGMVLVTIFVTCPFVVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSV 223

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1278639224 173 LGGSIAGETRVVSIAIYDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQRVMNPLK 230
Cdd:PRK11602  224 VSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRLENQEK 281
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 50-226 5.17e-13

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 66.57  E-value: 5.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  50 VAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERL---GLPHLAFSF--WGILVGSVIYSLPFAVQPLREAFGAIDTR 124
Cdd:PRK15050  111 VGRFIDTFVAFPSFLITLAFTFLYGSAGSVNIALQRLfglEAPPLDFLYspGGVILAEITFYTPFVVRPLLAAFAQLDAR 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 125 LLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSiagetRVVSIAIYDYTQA---LNYGAAH 201
Cdd:PRK15050  191 QLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAK-----DVVTLPVLIYSKAivdFDYPTAC 265

                         170       180
                  ....*....|....*....|....*
gi 1278639224 202 RLSAILLGFSFLTLMLFYAINQRVM 226
Cdd:PRK15050  266 AIAVVNLALSLGLYALYRRVNRRAG 290
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 34-208 9.09e-10

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 56.01  E-value: 9.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  34 PLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAvggtlerLGLPHLAFSFWGILVGSVIYSLPFAVQP 113
Cdd:NF038017   18 PLGALLALRRFPGRRLVISLLNTLMGLPPVVVGLIVYLLLSRSGP-------LGFLGLLYTPTAMIIAQAVLALPIVAGL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 114 LREAFGAIDTRLLDAAATMRAGALDRFFSVVLPlSRSGILTAVVITFAHTVGEFGVIAMLGGSIAGETRVVSIAIYDYTQ 193
Cdd:NF038017   91 TLAAVQGLDPELRLQILSLGATRWQALWTLLKE-ARFALLAAVLAGFGRAISEVGAVMMVGGNIRGYTRVLTTAIVLETS 169

                         170
                  ....*....|....*
gi 1278639224 194 ALNYGAAHRLSAILL 208
Cdd:NF038017  170 KGNFDLALALGIILL 184
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 12-176 1.36e-09

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 57.00  E-value: 1.36e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  12 QAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLP-- 89
Cdd:PRK09497   63 EVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIdt 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  90 --HLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEF 167
Cdd:PRK09497  143 piRIMFTESAVIIGLVYILLPFMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMF 222


                  ....*....
gi 1278639224 168 GVIAMLGGS 176
Cdd:PRK09497  223 YVSDLLGGA 231
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 34-175 3.46e-09

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 55.87  E-value: 3.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  34 PLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLP----HLAFSFWGILVGSVIYSLPF 109
Cdd:PRK10683  119 PLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIdqplTILHTNLAVYIGIVYAYLPF 198

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278639224 110 AVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGG 175
Cdd:PRK10683  199 MVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGG 264
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 34-225 3.24e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.83  E-value: 3.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  34 PLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGgtlerlglphlaFSFWGILVGSVIYSLPFAVQP 113
Cdd:pfam00528   3 PLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILG------------HGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 114 LREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSIA-GETRVVSIAIYDYT 192
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGlGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1278639224 193 QALNYGAAhrLSAILLGFSFLTLMLFYAINQRV 225
Cdd:pfam00528 151 EIQGPVLA--AALILLLLNLLVDILQRLLDPRV 181
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 11-160 8.75e-07

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 48.55  E-value: 8.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  11 WQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTV--IGFYLLIVlgpqgavggtleRLGl 88
Cdd:COG0395    73 GRYLLNSLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVllIPLYLLFR------------QLG- 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278639224  89 phLAFSFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITF 160
Cdd:COG0395   140 --LLNTYWGLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTF 209
YnjC COG4135
ABC-type uncharacterized transport system YnjBCD, permease component [General function ...
 1-165 2.73e-05

ABC-type uncharacterized transport system YnjBCD, permease component [General function prediction only];


Pssm-ID: 443310 [Multi-domain]  Cd Length: 564  Bit Score: 44.48  E-value: 2.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224   1 MNFAGITPGEWQAIWLTAKLAGLTTLILLLLSAPLAWWLARSGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGPQGAVG 80
Cdd:COG4135   345 RFWQRAAPGLLEPLGNTLLLALASALIALVLVLACLEAEARRGRRPGRRALWLLYLPLLVPQIAFLFGLQVLLLRLGLDG 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  81 GtlerlglphlafsFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITF 160
Cdd:COG4135   425 T-------------WLAVIWAHLVFVLPYVFLSLAGPWRALDPRYAQVAASLGASPWRVFWRVKLPLLLRPILTAAAVGF 491


                  ....*
gi 1278639224 161 AHTVG 165
Cdd:COG4135   492 AVSVA 496
thiP PRK09433
thiamine transporter membrane protein; Reviewed
 35-217 3.35e-05

thiamine transporter membrane protein; Reviewed


Pssm-ID: 181853 [Multi-domain]  Cd Length: 525  Bit Score: 44.06  E-value: 3.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  35 LAWWLARSGSRLV----NSVAALVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLPhLAFS---FWGILVGSVIYSL 107
Cdd:PRK09433   63 PAIPLARALYRRRfpgrGLLLRLCAMTLVLPVLVAVFGLLSVYGRSGWLAQLLQALGLE-WPFSiygLQGILLAHVFFNL 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 108 PFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSIAGETrvVSIA 187
Cdd:PRK09433  142 PLATRLLLQALESIPAEQRQLAAQLGMRGWQFFRLVEWPYLRRQLPPVAALIFMLCFTSFATVLTLGGGPKATT--IELA 219

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1278639224 188 IYdytQALNY----GAAHRLSAILLGFSFLTLML 217
Cdd:PRK09433  220 IY---QALSFdfdlARAALLALLQMVLCLGLVLL 250
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 42-225 6.61e-05

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 43.02  E-value: 6.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  42 SGSRLVNSVAALVALPLVLPPTVIGFYLLIVLGP--QGAVGGTLERlGLPHLAFSFWGILVGSVIYS---LPFAVQPLRE 116
Cdd:TIGR02138  94 APKRVRSVLKPVVELLAGIPSVVYGFWGLFVLVPflKPHFQPFLGS-NLGLIPLFGGPILTAGIVLAimiLPTIASISRD 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 117 AFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSIA----------GETRVVSI 186
Cdd:TIGR02138 173 ALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVLGLGRALGETMAVTMVIGNVFpisplslfdpGTTITSLI 252

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1278639224 187 AI---YDYTQALNYGAAHRLSAILLGFSFLTLMLFYAINQRV 225
Cdd:TIGR02138 253 ANqfgEASGGSVHTSALFALGLVLFVITLLVNILARYIVRRR 294
thiP TIGR01253
thiamine ABC transporter, permease protein; The model describes thiamine ABC transporter, ...
 53-231 3.20e-04

thiamine ABC transporter, permease protein; The model describes thiamine ABC transporter, permease protein in bacteria. The protein belongs to the larger ABC transport system. It consists of atleast three components: the inner mebrane permease; thiamine binding protein; an ATP-binding subunit. It has been experimentally demonstrated that the mutants in the various steps in the de novo synthesis of the thiamine and the biologically active form, namely thiamine pyrophosphate can be exogenously supplemented with thiamine, thiamine monophosphate (TMP) or thiamine pyrophosphate (TPP). [Transport and binding proteins, Other]


Pssm-ID: 130320 [Multi-domain]  Cd Length: 519  Bit Score: 41.44  E-value: 3.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  53 LVALPLVLPPTVIGFYLLIVLGPQGAVGGTLERLGLPHLA--FSFWGILVGSVIYSLPFAVQPLREAFGAI--DTRLLDA 128
Cdd:TIGR01253  88 LCALTFILPALVAIFGIIGIYGRQGWLATLANLFGLEWQFhiYGLQGILIAHLFFNIPLAAQLFLQALENIpgEQRQLAA 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 129 AATMRAGALDRFfsVVLPLSRSGILTAVVITFAHTVGEFGVIAMLGGSIAGETrvVSIAIYdytQALNYGAAHRLSAILL 208
Cdd:TIGR01253 168 QLGLQGWHFFKF--VEWPVFRQQCLPTAALIFMLCFASFATVLSLGGGPQATT--IELAIY---QAILFDFDLAKAALFA 240

                         170       180
                  ....*....|....*....|...
gi 1278639224 209 GFSFLTLMLFYAINQRVMNPLKP 231
Cdd:TIGR01253 241 LLQFVCCLGLFLLSQRFSKAIAN 263
thiP PRK09433
thiamine transporter membrane protein; Reviewed
 11-174 6.94e-04

thiamine transporter membrane protein; Reviewed


Pssm-ID: 181853 [Multi-domain]  Cd Length: 525  Bit Score: 40.20  E-value: 6.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  11 WQAIWLTAKLAGLTTLILLLLSAPLAW----WLARSGSRLVNSVAALVALPLVLPPTVI--GFYLLIvlgpqgavggtLE 84
Cdd:PRK09433  318 WQALWTSLRIALAAALLAVVLTMMLLWssreLRLRQRKLAAQALELSGMLILAMPGIVLatGLFLLL-----------RN 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  85 RLGLPHLAfsFWGILVGSVIYSLPFAVQPLREAFGAIDTRLLDAAATMRAGALDRFFSVVLPLSRSGILTAVVITFAHTV 164
Cdd:PRK09433  387 TTDLPASA--LGIVILTNALMALPYALRVLEPPMRDIAARYGRLCQSLGIRGWSRLRLIELRALRRPLAQAFAFACALSL 464

                         170
                  ....*....|
gi 1278639224 165 GEFGVIAMLG 174
Cdd:PRK09433  465 GDFGVIALFG 474
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 62-224 5.56e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 36.99  E-value: 5.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224  62 PTVI-GFYLLIVLGPqgavggtLERLGLPHLAFSFwGILVGSVIYS---LPFAVQPLREAFGAIDTRLLDAAATMRAGAL 137
Cdd:COG0573   127 PSVVyGFWGLFVLVP-------LLRDLFPWPPSGF-SLLTAGIVLAimiLPTITSLSRDALRAVPRSLREAALALGATRW 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278639224 138 DRFFSVVLPLSRSGILTAVVITFAHTVGEFGVIAMlggsIAGETRVVSIAIYDYTQ------ALNYGAA-----HRLSAI 206
Cdd:COG0573   199 ETIRKVVLPAARSGIIAAVILGLGRALGETMAVLM----VAGNAPQIPFSLFDPGRtltaliALEFGEApfgslHYSALF 274

                         170       180
                  ....*....|....*....|...
gi 1278639224 207 LLG-----FSFLTLMLFYAINQR 224
Cdd:COG0573   275 ALGlvlfvITLLVNLLARLIVRR 297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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