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Conserved domains on  [gi|1279226875|gb|PJE68472.1|]
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Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit A [Candidatus Shapirobacteria bacterium CG10_big_fil_rev_8_21_14_0_10_38_8]

Protein Classification

amidase( domain architecture ID 10000643)

amidase catalyzes the hydrolysis of a monocarboxylic acid amide to form a monocarboxylate and ammonia; similar to aspartyl/glutamyl-tRNA synthase subunit A (GatA), which is part of a heterotrimeric complex that forms correctly charged Gln-tRNA(Gln) or Asn-tRNA(Asn) through the transamidation of misacylated Glu-tRNA(Gln) or Asp-tRNA(Asn)

CATH:  3.90.1300.10
Gene Ontology:  GO:0003824
SCOP:  3001251|4002446

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-460 0e+00

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


:

Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 577.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFR---ERKPLLGIPIALKD 77
Cdd:COG0154     2 SDLAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAageALGPLAGVPVAVKD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  78 LYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPggsssgsav 157
Cdd:COG0154    82 LIDVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPWDPDRTPggssggsaa 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 158 aaaadeclaaMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATS 237
Cdd:COG0154   162 avaaglvplaLGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVADAALLLDVLAGPDPRDPTS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 238 SNKPVEDYLEGIRgnRGTRRIRIGLPKEYFG-EGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYIIQPAEV 316
Cdd:COG0154   242 APAPVPDYLAALD--RDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALGAEVVEVDLPDLDEALAAYYTIAAAEA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 317 SSNLARYdgirFGNDRDKFGDEAKRRIMLGTYilsagYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLG 396
Cdd:COG0154   320 AANLADL----LRTRPEGFGPEVRRRILLGAY-----YSAADYLKAQRVRALLRRDFAAAFEDYDVLLTPTTPTPAPPIG 390

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279226875 397 EK---VNDPMQM-YLADIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVGKIYEQST 460
Cdd:COG0154   391 ELdadIDPALAMnYLLDRFTAPANLAGLPALSVPAGFTaDGLPVGLQLIGPPGDEATLLRLAAALEQAL 459
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-460 0e+00

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 577.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFR---ERKPLLGIPIALKD 77
Cdd:COG0154     2 SDLAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAageALGPLAGVPVAVKD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  78 LYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPggsssgsav 157
Cdd:COG0154    82 LIDVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPWDPDRTPggssggsaa 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 158 aaaadeclaaMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATS 237
Cdd:COG0154   162 avaaglvplaLGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVADAALLLDVLAGPDPRDPTS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 238 SNKPVEDYLEGIRgnRGTRRIRIGLPKEYFG-EGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYIIQPAEV 316
Cdd:COG0154   242 APAPVPDYLAALD--RDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALGAEVVEVDLPDLDEALAAYYTIAAAEA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 317 SSNLARYdgirFGNDRDKFGDEAKRRIMLGTYilsagYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLG 396
Cdd:COG0154   320 AANLADL----LRTRPEGFGPEVRRRILLGAY-----YSAADYLKAQRVRALLRRDFAAAFEDYDVLLTPTTPTPAPPIG 390

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279226875 397 EK---VNDPMQM-YLADIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVGKIYEQST 460
Cdd:COG0154   391 ELdadIDPALAMnYLLDRFTAPANLAGLPALSVPAGFTaDGLPVGLQLIGPPGDEATLLRLAAALEQAL 459
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 12-458 0e+00

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 573.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  12 REGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRgfRERKPLLGIPIALKDLYCTKGIKKTAGSK 91
Cdd:TIGR00132   2 RQLLKKKEISIKEVLEASLDRIEANKDKINAFLEVTVEKALKQAKKLDK--AILTPLAGIPIAVKDNISTKGIVTTCASK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  92 VLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTD 171
Cdd:TIGR00132  80 ILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPWNLDRVPGGSSGGSAAAVAADLAPFSLGSD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 172 TGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSNKPVEDYLEGIRg 251
Cdd:TIGR00132 160 TGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISGHDKRDSTSAKVPDPEFFEELK- 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 252 nRGTRRIRIGLPKEYFGEgLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYIIQPAEVSSNLARYDGIRFG-- 329
Cdd:TIGR00132 239 -KDLKGLKVGVVKEFSEE-MDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYYIISPSEASSNLARYDGIRYGyr 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 330 ------------NDRDK-FGDEAKRRIMLGTYILSAGYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLG 396
Cdd:TIGR00132 317 ieepnslkelyaKTRAEgFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFLKLFEEVDVIVSPTAPTLPFKIG 396

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279226875 397 EKVNDPMQMYLADIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVGKIYEQ 458
Cdd:TIGR00132 397 EKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKeKGLPIGLQIIGKCFDDKTLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
24-449 8.90e-172

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 489.50  E-value: 8.90e-172
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  24 ELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDR---GFRERKPLLGIPIALKDLYCTKGIKKTAGSKVLENYIPVY 100
Cdd:pfam01425   1 ELVEAFLDRIEAANPKLNAFVTVFFDEALAQAAAADKqraAGDPKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 101 DATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPA 180
Cdd:pfam01425  81 DATVVERLRKAGAVILGKTNMDEFAMGSSTENSVFGPTRNPWDLSRTPGGSSGGSAAAVAAGLVPLAIGTDTGGSIRIPA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 181 SFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSNKPVEDYLEGIRGNRgtRRIRI 260
Cdd:pfam01425 161 SFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSLPPPVPDYAEPVKKSL--KGLRI 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 261 GLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYIIQPAEVSSNLARYDGIRFGND--------- 331
Cdd:pfam01425 239 GVYREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDGVPSGPDdlselyprt 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 332 -RDKFGDEAKRRIMLGTYILSAGYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLGEKVNDPMQMYLADI 410
Cdd:pfam01425 319 rAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPRLGEPDDSPLVMYNLDD 398

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 1279226875 411 YT---VTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKML 449
Cdd:pfam01425 399 FTagvVPVNLAGLPAISLPAGFTaDGLPVGVQIIGKPGDEETL 441
PRK07235 PRK07235
amidase; Provisional
 67-460 5.83e-82

amidase; Provisional


Pssm-ID: 235979 [Multi-domain]  Cd Length: 502  Bit Score: 261.86  E-value: 5.83e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  67 PLLGIPIALKDLYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLER 146
Cdd:PRK07235   87 KLAGKTVALKDNVAVAGVPMMNGSSTLEGFVPSFDATVVTRLLDAGATIVGKATCEDLCFSGGSHTSDPGPVHNPRDPGY 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 147 TPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGV 226
Cdd:PRK07235  167 SAGGSSSGSAALVAAGEVDMAIGGDQGGSIRIPSAWCGIYGMKPTHGLVPYTGAFPIERTIDHLGPMTATVRDNALLLEV 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 227 TAGFDPKDATSSNKP-VEDYLEGIRgnRGTRRIRIGLPKEYFG-EGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYA 304
Cdd:PRK07235  247 IAGRDGLDPRQPAQPpVDDYTAALD--RGVKGLKIGILREGFGlPNSEPEVDEAVRAAAKRLEDLGATVEEVSIPLHRLA 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 305 LAAYYII------------------QPAEVSSNLARYDGIRFGNDRDKFGDEAKRRIMLGTYILSAgYYDAYYLKAMKVR 366
Cdd:PRK07235  325 LAIWNPIategataqmmlgngygfnWKGLYDTGLLDAFGAGWRERADDLSETVKLVMLLGQYGLER-YHGRYYAKARNLA 403

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 367 TLIKRDFNEVFKKVDVLISPVSPNPPFKLGEKvNDPMQMYLADIYTVTANLA-----GIPGLSIPAGFVDGLPVGMQILG 441
Cdd:PRK07235  404 RRLRAAYDEALRKYDLLVMPTTPMVATPLPAP-DASREEYVSRALEMIANTApfdvtGHPAMSVPCGLVDGLPVGLMLVG 482

                         410
                  ....*....|....*....
gi 1279226875 442 PQFSEKMLFQVGKIYEQST 460
Cdd:PRK07235  483 RHFDEATILRAAAAFEASG 501
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-460 0e+00

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 577.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFR---ERKPLLGIPIALKD 77
Cdd:COG0154     2 SDLAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAageALGPLAGVPVAVKD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  78 LYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPggsssgsav 157
Cdd:COG0154    82 LIDVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPWDPDRTPggssggsaa 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 158 aaaadeclaaMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATS 237
Cdd:COG0154   162 avaaglvplaLGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVADAALLLDVLAGPDPRDPTS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 238 SNKPVEDYLEGIRgnRGTRRIRIGLPKEYFG-EGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYIIQPAEV 316
Cdd:COG0154   242 APAPVPDYLAALD--RDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALGAEVVEVDLPDLDEALAAYYTIAAAEA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 317 SSNLARYdgirFGNDRDKFGDEAKRRIMLGTYilsagYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLG 396
Cdd:COG0154   320 AANLADL----LRTRPEGFGPEVRRRILLGAY-----YSAADYLKAQRVRALLRRDFAAAFEDYDVLLTPTTPTPAPPIG 390

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279226875 397 EK---VNDPMQM-YLADIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVGKIYEQST 460
Cdd:COG0154   391 ELdadIDPALAMnYLLDRFTAPANLAGLPALSVPAGFTaDGLPVGLQLIGPPGDEATLLRLAAALEQAL 459
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 12-458 0e+00

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 573.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  12 REGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRgfRERKPLLGIPIALKDLYCTKGIKKTAGSK 91
Cdd:TIGR00132   2 RQLLKKKEISIKEVLEASLDRIEANKDKINAFLEVTVEKALKQAKKLDK--AILTPLAGIPIAVKDNISTKGIVTTCASK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  92 VLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTD 171
Cdd:TIGR00132  80 ILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPWNLDRVPGGSSGGSAAAVAADLAPFSLGSD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 172 TGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSNKPVEDYLEGIRg 251
Cdd:TIGR00132 160 TGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISGHDKRDSTSAKVPDPEFFEELK- 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 252 nRGTRRIRIGLPKEYFGEgLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYIIQPAEVSSNLARYDGIRFG-- 329
Cdd:TIGR00132 239 -KDLKGLKVGVVKEFSEE-MDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYYIISPSEASSNLARYDGIRYGyr 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 330 ------------NDRDK-FGDEAKRRIMLGTYILSAGYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLG 396
Cdd:TIGR00132 317 ieepnslkelyaKTRAEgFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFLKLFEEVDVIVSPTAPTLPFKIG 396

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279226875 397 EKVNDPMQMYLADIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVGKIYEQ 458
Cdd:TIGR00132 397 EKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKeKGLPIGLQIIGKCFDDKTLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
24-449 8.90e-172

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 489.50  E-value: 8.90e-172
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  24 ELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDR---GFRERKPLLGIPIALKDLYCTKGIKKTAGSKVLENYIPVY 100
Cdd:pfam01425   1 ELVEAFLDRIEAANPKLNAFVTVFFDEALAQAAAADKqraAGDPKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 101 DATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPA 180
Cdd:pfam01425  81 DATVVERLRKAGAVILGKTNMDEFAMGSSTENSVFGPTRNPWDLSRTPGGSSGGSAAAVAAGLVPLAIGTDTGGSIRIPA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 181 SFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSNKPVEDYLEGIRGNRgtRRIRI 260
Cdd:pfam01425 161 SFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSLPPPVPDYAEPVKKSL--KGLRI 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 261 GLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYIIQPAEVSSNLARYDGIRFGND--------- 331
Cdd:pfam01425 239 GVYREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDGVPSGPDdlselyprt 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 332 -RDKFGDEAKRRIMLGTYILSAGYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLGEKVNDPMQMYLADI 410
Cdd:pfam01425 319 rAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPRLGEPDDSPLVMYNLDD 398

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 1279226875 411 YT---VTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKML 449
Cdd:pfam01425 399 FTagvVPVNLAGLPAISLPAGFTaDGLPVGVQIIGKPGDEETL 441
PRK07235 PRK07235
amidase; Provisional
 67-460 5.83e-82

amidase; Provisional


Pssm-ID: 235979 [Multi-domain]  Cd Length: 502  Bit Score: 261.86  E-value: 5.83e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  67 PLLGIPIALKDLYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLER 146
Cdd:PRK07235   87 KLAGKTVALKDNVAVAGVPMMNGSSTLEGFVPSFDATVVTRLLDAGATIVGKATCEDLCFSGGSHTSDPGPVHNPRDPGY 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 147 TPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGV 226
Cdd:PRK07235  167 SAGGSSSGSAALVAAGEVDMAIGGDQGGSIRIPSAWCGIYGMKPTHGLVPYTGAFPIERTIDHLGPMTATVRDNALLLEV 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 227 TAGFDPKDATSSNKP-VEDYLEGIRgnRGTRRIRIGLPKEYFG-EGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYA 304
Cdd:PRK07235  247 IAGRDGLDPRQPAQPpVDDYTAALD--RGVKGLKIGILREGFGlPNSEPEVDEAVRAAAKRLEDLGATVEEVSIPLHRLA 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 305 LAAYYII------------------QPAEVSSNLARYDGIRFGNDRDKFGDEAKRRIMLGTYILSAgYYDAYYLKAMKVR 366
Cdd:PRK07235  325 LAIWNPIategataqmmlgngygfnWKGLYDTGLLDAFGAGWRERADDLSETVKLVMLLGQYGLER-YHGRYYAKARNLA 403

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 367 TLIKRDFNEVFKKVDVLISPVSPNPPFKLGEKvNDPMQMYLADIYTVTANLA-----GIPGLSIPAGFVDGLPVGMQILG 441
Cdd:PRK07235  404 RRLRAAYDEALRKYDLLVMPTTPMVATPLPAP-DASREEYVSRALEMIANTApfdvtGHPAMSVPCGLVDGLPVGLMLVG 482

                         410
                  ....*....|....*....
gi 1279226875 442 PQFSEKMLFQVGKIYEQST 460
Cdd:PRK07235  483 RHFDEATILRAAAAFEASG 501
PRK07488 PRK07488
indoleacetamide hydrolase;
1-458 1.78e-80

indoleacetamide hydrolase;


Pssm-ID: 236030 [Multi-domain]  Cd Length: 472  Bit Score: 256.82  E-value: 1.78e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQInKTNSKLNSFITVCEEEATEKAVEIDRGFR--ERKPLLGIPIALKDL 78
Cdd:PRK07488    6 PDVASLSLTEAAAALRSGRLSCLELVEALLARA-AALAPLNAFTTVDAEGALAAARRIDAQRAagAALLLAGVPIVIKDN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  79 YCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVA 158
Cdd:PRK07488   85 INTAGMPTTAGTPALLGFVPATDAPVVQRLLDAGAVPLGKANMHELAFGITSNNGAFGAVRNPYDPARIAGGSSGGTAAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 159 AAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGfdpkDATSS 238
Cdd:PRK07488  165 VAARLAPAGLGTDTGGSVRIPAALCGVVGLRPTVGRYSGDGVVPISHTRDTVGPIARSVADLALLDAVITG----DAALP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 239 NKPvedylegirgnrGTRRIRIGLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYA-------LAAYyii 311
Cdd:PRK07488  241 APV------------ALAGLRLGVPAAPFWDGLDPDVAAVAEAALAKLAAAGVTFVELDLPGLHELneavgfpIALY--- 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 312 qpaEVSSNLARYdgIRFGNDRDKFGDEAKR----------RIMLGTYILSAGYYDAyylkAMKV-RTLIKRDFNEVFK-- 378
Cdd:PRK07488  306 ---EALADLRAY--LRENGAGVSFEELVARiaspdvraifRDLLDPPQISEDAYRA----ALDVgRPRLQAWYRQAFArh 376

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 379 KVDVLISPVSP--NPPFKLGEKVNDPMQMY-LADIY---TVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQ 451
Cdd:PRK07488  377 GLDAILFPTTPltAPPIGDDDTVILNGAAVpTFARVirnTDPASNAGLPGLSLPAGLTpHGLPVGLELDGPAGSDRRLLA 456


                  ....*..
gi 1279226875 452 VGKIYEQ 458
Cdd:PRK07488  457 IGRALER 463
PRK09201 PRK09201
AtzE family amidohydrolase;
1-458 1.18e-76

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 246.80  E-value: 1.18e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFRERK---PLLGIPIALKD 77
Cdd:PRK09201    2 MNLSSLSAAEIAAAVRAGELSARAVAQATLARIARANPQLNAFTAVTAERALAEAARIDAARAAGEplgPLAGVPFAVKN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  78 LYCTKGIKKTAGSKVLENYIPV-YDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSA 156
Cdd:PRK09201   82 LFDVAGLTTLAGSKINRDRPPAtRDATAVRRLEAAGAVLVGALNMDEYAYGFTTENSHYGATRNPHDLTRIAGGSSGGSA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 157 VAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDAT 236
Cdd:PRK09201  162 AAVAAGLVPFTLGSDTNGSIRVPASLCGIFGLKPTYGRLSRAGSFPFVASLDHIGPFARSVADLALVYDVLQGPDPQDPF 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 237 SSNKPVEDYLEGIrgNRGTRRIRIGLPKEYFGEGLDARIKE---KILGALGVLEdlgakiiEVSLPHTKYALAAYYIIQP 313
Cdd:PRK09201  242 QADRPAEPTAPLL--DRGAEGLRIAVLGGYFAQWADPEARAavdRVAKALGATR-------EVELPEAARARAAAFIITA 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 314 AEvSSNLARYDGIRFGNDrdkFgDEAKR-RIMLGTYILSagyydAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPP 392
Cdd:PRK09201  313 SE-GGNLHLPALRTRPQD---F-DPASRdRLLAGAMLPA-----AWYVQAQRFRRWFRQAVLELFEHVDVLIAPATPCSA 382

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279226875 393 FKLGEK------VNDPMQMYLAdIYTVTANLAGIPGLSIPAGFVDGLPVGMQILGPQFSEKMLFQVGKIYEQ 458
Cdd:PRK09201  383 PLIGQEtmridgVELPVRANLG-ILTQPISFIGLPVVAVPLRTPGGLPIGVQLIAAPWREDLALRAAAALEQ 453
PRK08137 PRK08137
amidase; Provisional
 1-461 5.59e-72

amidase; Provisional


Pssm-ID: 236161 [Multi-domain]  Cd Length: 497  Bit Score: 235.82  E-value: 5.59e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINK---TNSKLNSFITVcEEEATEKAVEID---RGFRERKPLLGIPIA 74
Cdd:PRK08137    1 QTALEERAGALQAAMPAGAAPASQLTRAYLQRIARidrDGPRLNAVIEL-NPDAEADAAALDaerKAGKVRGPLHGIPVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  75 LKD-LYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWA-----HGASGENSDFGPTRNPWNLERTP 148
Cdd:PRK08137   80 LKDnIDAADPMPTTAGSLALAGNRPTRDAFLVARLRDAGAVILGKANLSEWAnfrstRSSSGWSARGGLTRNPYALDRSP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 149 GGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTA 228
Cdd:PRK08137  160 CGSSSGSGAAVAAGLAAVAIGTETDGSITCPAAINGLVGLKPTVGLVSRDGIVPISHSQDTAGPMTRTVADAAAVLTAIA 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 229 GFDPKDATSSNKPVE--DYLEGIRGNrGTRRIRIGLPKEYFGE--GLDARIKEkilgALGVLEDLGAKIIEVSLPHTKYA 304
Cdd:PRK08137  240 GGDPADPATASAPAPavDYVAALDAD-ALRGARLGVARNYLGYhpEVDAQFER----ALAELKAAGAVVIDVVDLDDGDW 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 305 LAAYYIIQPAEVSSNLARY-------DGIRFGNDRDKFGDEAKRRIM--LGTYIL-----SAGYYDAYYLKAM-KVRTLI 369
Cdd:PRK08137  315 GEAEKVVLLHEFKAGLNAYlrstaphAPVRTLADLIAFNRAQHAREMpyFGQELFeqaqaAPGLDDPAYLDALaDAKRLA 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 370 KRD-FNEVFKK--VDVLISPvSPNPPFKLgekvnDPMQ--MYLADIYTVTAnLAGIPGLSIPAGFVDGLPVGMQILGPQF 444
Cdd:PRK08137  395 GPEgIDAALKEhrLDALVAP-TTGPAWLI-----DLINgdSFGGSSSTPAA-VAGYPHLTVPMGQVQGLPVGLSFIGAAW 467

                         490
                  ....*....|....*..
gi 1279226875 445 SEKMLFQVGKIYEQSTH 461
Cdd:PRK08137  468 SEARLLELGYAYEQATH 484
PRK07139 PRK07139
amidase; Provisional
 66-451 1.18e-68

amidase; Provisional


Pssm-ID: 235945 [Multi-domain]  Cd Length: 439  Bit Score: 225.31  E-value: 1.18e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  66 KPLLGIPIALKDLYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLE 145
Cdd:PRK07139   35 GPLANCVFTIKDNFATSEGPTHASSKSLENFKPSYNATVVQKLINAGAKPVAKVHCDELGLGGTGLFSAFGLIKNPLDSS 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 146 RTpGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILG 225
Cdd:PRK07139  115 KL-VGGSSSGSAATFNKNISFAIGSDTGDSVRLPASFIGKVGFKPSYGAISRYGLFAYASSLDTVAYFTHNVNDAIILSK 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 226 VTAGFDPKDATSSNKPVEDylegirgNRGTRRIRIGLpKEYFGEgLDARIKEKILGALGVLEDLGAKI--IEVSLPHTKY 303
Cdd:PRK07139  194 VLFGKDENDLTSVDVKINN-------VKKTKPKKVAY-LDCFKE-LEEYVAKKYKKLINILKSENIEVekIKIDEKLLKA 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 304 ALAAYYIIQPAEVSSNLARYDGIRFGNDRD--------------KFGDEAKRRIMLGTYILSAGYYDAYYLKAMKVRTLI 369
Cdd:PRK07139  265 IKPVYKIISYSEASSNLANLNGIAFGNREKgssweeimintrseGFGKMVQKRLILGSYFLEEENQEKYFLKAKKVRRVI 344

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 370 KRDFNEVFKKVDVLISPVSPN--PPFKLGEKVNDPmqmYLADIYTvTANLAGIPGLSIPAGFVDGLPVGMQILGPQFSEK 447
Cdd:PRK07139  345 KNYYESIHNKFDIVIYPAYADiaPDIDENENKSDN---YMDYILT-ISNLVGNPSLSIPLGKYNNLPFNLAIDSKIYDDE 420


                  ....
gi 1279226875 448 MLFQ 451
Cdd:PRK07139  421 KLLS 424
PRK06169 PRK06169
putative amidase; Provisional
 1-458 1.51e-67

putative amidase; Provisional


Pssm-ID: 180437 [Multi-domain]  Cd Length: 466  Bit Score: 222.98  E-value: 1.51e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFRERKP---LLGIPIALKD 77
Cdd:PRK06169    2 TDLADLTAVELLAAYRRGELSPVEATQAVLDRIDRRDPAVNAFCLVDAEGALAAARASEERWRRGEPcglLDGVPVSIKD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  78 LYCTKGIKKTAGSKVLENYIP-VYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSA 156
Cdd:PRK06169   82 IFLTRGWPTLRGSRAIDADGPwDVDAPAVARLREAGAVLLGKTTTPEFGWKGVTDSPLYGITRNPWDTRLTAGGSSGGAA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 157 VAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMaSSLDCMGHLTKTVEDSALILGVTAGFDPKDAT 236
Cdd:PRK06169  162 AAVALGMGPLSVGTDGGGSVRIPASFCGTFGFKPTFGRVPLYPASPF-GTLAHVGPMTRTVADAALLLDVIARPDARDWS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 237 SSNKPVEDYLEGIRgnRGTRRIRIGLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPHTkyalaayyiiQPAEV 316
Cdd:PRK06169  241 ALPPPTTSFLDALD--RDVRGLRIAYSPTLGYVDVDPEVAALVAQAVQRLAALGARVEEVDPGFS----------DPVEA 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 317 -----SSNLARYDGiRFGNDRDKFGDEAKRRIMLGTYILSAgyydAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNP 391
Cdd:PRK06169  309 fhvlwFAGAARLLR-ALPPGQRALLDPGLRRIAERGATYSA----SDYLDATAVRAALGARMGAFHERYDLLLTPTLPIP 383

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279226875 392 PFKLGEKVndPMQMYLADI-----YTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVGKIYEQ 458
Cdd:PRK06169  384 AFEAGHDV--PPGSGLTDWtqwtpFTYPFNLTQQPAASVPCGFTaAGLPVGLQIVGPRHSDDLVLRVARAYEQ 454
PRK07042 PRK07042
amidase; Provisional
 1-458 1.11e-61

amidase; Provisional


Pssm-ID: 235915 [Multi-domain]  Cd Length: 464  Bit Score: 207.52  E-value: 1.11e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAveidRGFRER-------KPLLGIPI 73
Cdd:PRK07042    2 TALHDLSAVELLAGYRARSLSPVEVTEAVLAHIARWEPHLNALYAFDPEAARAAA----RASTARwakgeplGPLDGVPV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  74 ALKDLYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSS 153
Cdd:PRK07042   78 TIKENIATRGVPVPLGTAATDLPPAAADAPPAARLREAGAVILAKTTMPDYGMLSSGLSSFHGLTRNPWDLDQNPGGSSA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 154 GSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVsrygvvamasSLD------CMGHLTKTVEDSALILGVT 227
Cdd:PRK07042  158 GAGAAAAAGYGPLHLGTDIGGSVRLPAGWCGIVGLKPSLGRI----------PIDppytgrCAGPMTRTVDDAALLMSVL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 228 AGFDPKDATSsnKPVEDyLEGIRGNRGTRRIRIGLPKEY-FGEGLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALA 306
Cdd:PRK07042  228 SRPDARDGTS--LPPQD-IDWSDLDIDVRGLRIGLMLDAgCGLAVDPEVRAAVEAAARRFEAAGAIVEPVPPFLTRAMLD 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 307 AyyiiqpaevssnLARYDGIRFGNDRDKFGDEAKRRIMlgTYI---------LSAgyYDAYY----LKAMKVRTLikrdf 373
Cdd:PRK07042  305 G------------LDRFWRARLWSDLAALPPERRAKVL--PYIrrwaeggadLSG--VEAVRgfnqTFAMRAAAA----- 363

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 374 nEVFKKVDVLISPVSPNPPF--KLGEKVNDPMQMYLADIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLF 450
Cdd:PRK07042  364 -RLFAEFDYVLSPVAPVPAFpaEWASPTNDPARPFEHIAFTVPWNMSEQPAASINCGFTrDGLPIGLQIVGPRFDDLGVL 442


                  ....*...
gi 1279226875 451 QVGKIYEQ 458
Cdd:PRK07042  443 RLAKAFEG 450
PRK06061 PRK06061
amidase; Provisional
 24-449 2.15e-58

amidase; Provisional


Pssm-ID: 235686 [Multi-domain]  Cd Length: 483  Bit Score: 199.54  E-value: 2.15e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  24 ELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFR--ERKPLLGIPIALKDLYCTKGIKKTAGSkvlENYIP--V 99
Cdd:PRK06061   36 ELVRRSLRRIEASQPTLNAFRVVRAEAALAEAAEADRRRAagDRLPLLGVPIAVKDDVDVAGVPTAFGT---AGEVPpaT 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 100 YDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLP 179
Cdd:PRK06061  113 ADSEVVRRLRAAGAVIVGKTNTCELGQWPFTSGPAFGHTRNPWSRDHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSVRIP 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 180 ASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSNKPVE-DYLEgirgnRGTRRI 258
Cdd:PRK06061  193 AAWTHLVGIKPQRGRISTWPLPEAFNGLTVNGPLARTVADAALLLDAASGNHPGDRHRPPPVTVsDAVG-----RAPGPL 267

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 259 RIGL----PKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPhtkYALAayyiiqpaeVSSN-LAR-YDGIRFGNDR 332
Cdd:PRK06061  268 RIALstrfPFTGFPAKLHPEIRAAVRRVAEQLALLGHTVVPADPD---YGLR---------LGLNfLPRsTAGLRDWAER 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 333 DKFGDEAKRRI--------MLGTYILSAGyydayylKAMKVRtlIKRDFNEVFKKVDVLISPVSPNPPFKLGEKVN---- 400
Cdd:PRK06061  336 LGDPVLLDPRTvsnarmgrLLSQAILRLA-------RAAEAA--AQRRVGSIFDIVDVVLAPTTAQPPPRVGAFDRlggw 406

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279226875 401 --DPMqMYLADIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKML 449
Cdd:PRK06061  407 atDRA-MIAACPYTWPWNVLGWPSINVPAGFTsDGLPIGAQLMGPANSEPLL 457
PRK07487 PRK07487
amidase; Provisional
 6-457 6.36e-57

amidase; Provisional


Pssm-ID: 236029 [Multi-domain]  Cd Length: 469  Bit Score: 195.19  E-value: 6.36e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   6 LTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGfRERK----PLLGIPIALKDLYCT 81
Cdd:PRK07487    8 LSAAELAAAVRSRDVSAREAAEAALARLDAVNPAINAVVDHRPEEALAQADAVDAA-RARGddpgPLAGVPVTVKVNVDQ 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  82 KGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAA 161
Cdd:PRK07487   87 AGFATTNGVRLQKDLIAPADSPVVDNLRKAGAVIIGRTNTPAFSYRWFTDNPLHGRTLNPWDPSLTPGGSSGGAAAAVAA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 162 DECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRY---------GVVAMASSldcmGHLTKTVEDSALILGVTAGFDP 232
Cdd:PRK07487  167 GIGAIAHGTDIGGSIRYPAYACGVHGLRPTLGRVPAYnassperpiGAQLMSVQ----GPLARTVADLRLALAAMAAPDP 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 233 KDATSSNKPVEDylegirgnrGTRRIRIGLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVS-LPHTKYALAAYYII 311
Cdd:PRK07487  243 RDPWWVPAPLEG---------PPRPKRVALCVRPDGLDVDPEVEAALRDAARRLEDAGWTVEEVDdTPPLREAAELQERL 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 312 QPAEVssnlarYDGIrfGNDRDKFGDEAKRRIMLGTYILSAGYYDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNP 391
Cdd:PRK07487  314 WLGDG------YEAL--LAAAEAEGDPGALAALRGQRAKARPLDLAGYMNALARRATLTRQWQLFFEDYPLLLMPVSAEL 385

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279226875 392 PFKLGEKVNDP---MQMYLADIYTVTANLAGIPGLSIPAGFVDGLPVGMQILGPQFSEKMLFQVGKIYE 457
Cdd:PRK07487  386 PFPDDLDRQGAegfRRVWEAQLPQIALPFMGLPGLSVPTGLVGGVPVGVQLVAGRFREDLCLAAGEAIE 454
allophanate_hyd TIGR02713
allophanate hydrolase; Allophanate hydrolase catalyzes the second reaction in an ATP-dependent ...
 43-454 1.09e-56

allophanate hydrolase; Allophanate hydrolase catalyzes the second reaction in an ATP-dependent two-step degradation of urea to ammonia and C02, following the action of the biotin-containing urea carboxylase. The yeast enzyme, a fusion of allophanate hydrolase to urea carboxylase, is designated urea amidolyase. [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 274265 [Multi-domain]  Cd Length: 561  Bit Score: 196.79  E-value: 1.09e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  43 FITVC-EEEATEKAVEID--RGFRERKPLLGIPIALKDLYCTKGIKKTAGSKVLEnYIPVYDATVVDKLKNAGAIIIGKT 119
Cdd:TIGR02713   4 WISLLsEEDLLAQAAALDarDARPERLPLYGVPFAVKDNIDVAGLPTTAACPAFA-YTPEEDATVVALLRAAGAIVVGKT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 120 NCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYG 199
Cdd:TIGR02713  83 NLDQFATGLVGTRSPYGAVRNAFDPAYISGGSSSGSAVAVARGLVPFALGTDTAGSGRVPAALNNIVGLKPTKGLVSTTG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 200 VVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSNKPVEdylegiRGNRGTRRIRIGLPK----EYFGEGLDARI 275
Cdd:TIGR02713 163 VVPACRSLDCVSIFALTVADAEQVLRIAAAPDARDPYSRPLPAA------ALRRFPPPPRVGVPRaaqlEFFGDSQAEAA 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 276 KEKilgALGVLEDLGAKIIEVSL-PHTKYALAAYYIIQPAEvssnlaRYDGIR-FGNDRDKFGDEAKRRIMLGTYILSA- 352
Cdd:TIGR02713 237 FAA---AVERLEALGVEVVEIDFaPFLETAALLYEGPWVAE------RYAAVGeFVEAQPDALDPVVRGIITSATRFSAa 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 353 -GYYDAYYLKAMKVRTLikrdfnEVFKKVDVLISPVSPNPPfKLGEKVNDPMQMYLA-DIYTVTANLAGIPGLSIPAGFV 430
Cdd:TIGR02713 308 dAFAAQYRLAALRRKAE------ALLAGVDVLLVPTAPTHP-TIEEVLADPVGLNSRlGTYTNFVNLLDLCAVAVPAGFR 380

                         410       420
                  ....*....|....*....|....*
gi 1279226875 431 -DGLPVGMQILGPQFSEKMLFQVGK 454
Cdd:TIGR02713 381 sDGLPFGVTLIGPAFHDAALASLGR 405
PRK07486 PRK07486
amidase; Provisional
 1-460 5.32e-55

amidase; Provisional


Pssm-ID: 236028 [Multi-domain]  Cd Length: 484  Bit Score: 190.61  E-value: 5.32e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEE-----EATEKAVEIDRGfRERKPLLGIPIAL 75
Cdd:PRK07486    7 DPIVRLSAHALSRAIRRRQVSCVEVMRAYLAHIERVNPAVNAIVALRDRdallaEAAEKDAALARG-EYRGWLHGMPQAP 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  76 KDLYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGS 155
Cdd:PRK07486   86 KDLAPTKGIRTTLGSPIFADQVPQEDAIVVERMRAAGAIFIGKTNTPEFGLGSHTYNPVYGATRNPYDPSRSAGGSSGGA 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 156 AVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGV----VAMASSLDCMGhltKTVEDSALILGVTAGFD 231
Cdd:PRK07486  166 AAALALRMLPVADGSDMMGSLRNPAAFNNVYGFRPSQGRVPHGPGgdvfVQQLGTEGPMG---RTVEDVALLLAVQAGYD 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 232 PKDATSSNKPVEDYLEGIrgNRGTRRIRIGLPKEYFGE-GLDARIKEKILGALGVLEDLGAKIIEVSLPHTKYALAAYYI 310
Cdd:PRK07486  243 PRDPLSLAEDPARFAQPL--EADLRGKRIAWLGDWGGYlPMEAGVLELCEAALATLRELGCDVEAALPAFPPERLWRAWL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 311 IQPAEVS--SNLARYDgirfgndrdkfgDEAKRRIMLGTYI--------LSAgyyDAYYlKAMKVRTLIKRDFNEVFKKV 380
Cdd:PRK07486  321 TLRHFLVggSLLALYR------------DPARRALLKPEAIweiegglaLTA---AQVY-EASVIRSAWYQALLRLFERY 384

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 381 DVLISPVSPNPPFKLGE---KVNDPMQMylaDIY------TVTANLAGIPGLSIPAGF-VDGLPVGMQILGPQFSEKMLF 450
Cdd:PRK07486  385 DFLALPTAQVFPFDAEWrwpRAIAGRAM---DTYhrwmevVVPATLAGLPAISVPVGFnAAGLPMGMQIIGPPRADLAVL 461

                         490
                  ....*....|
gi 1279226875 451 QVGKIYEQST 460
Cdd:PRK07486  462 QLAHAYEQAT 471
PRK06170 PRK06170
amidase; Provisional
 1-444 1.55e-49

amidase; Provisional


Pssm-ID: 235723 [Multi-domain]  Cd Length: 490  Bit Score: 175.99  E-value: 1.55e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   1 MKLNELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFR--ERKPLLGIPIALKDL 78
Cdd:PRK06170    7 DEWSFLPATELAAALAAGEVSSVELTDLAIARIERHDGKINAIVVRDFDRARAAARAADAARArgERGPLLGIPVTVKES 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  79 YCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVA 158
Cdd:PRK06170   87 FNVAGLPTTWGFPDLRDYVPAEDAVAVARLKAAGAVILGKTNVPLGLQDWQSYNEIYGTTNNPWDLARTPGGSSGGSAAA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 159 AAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVV-----AMASSLD--CMGHLTKTVEDSALILGVTAGFD 231
Cdd:PRK06170  167 LAAGFGALSIGSDIGGSLRVPAHYCGVYAHKPTLGLVPLRGHIpppapALPGQADlaVAGPMARSARDLALLLDVMAGPD 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 232 PKDAtssNKPVEDYLEGIRGNRgTRRIRIGLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVS--LP-----HTKY- 303
Cdd:PRK06170  247 PLDG---GVAYRLALPPARHGR-LKDFRVLVLDEHPLLPTDAAVRAAIERLAAALADAGARVVRHSplLPdlaesARLYm 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 304 -----ALAAYYiiQPAEVSSNLARYDGIRfGNDRDKfgDEAKRRIMLgtyiLSagYYDayYLKAMKVRTLIKRDFNEVFK 378
Cdd:PRK06170  323 rllfaASAARF--PPDAYADAQARAAGLS-ADDRSL--AAERLRGAV----LS--HRD--WLFADAAREELRAAWRRFFA 389

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279226875 379 KVDVLISPVSPNPPFKLGEKvNDPMQMYLaDI------YT---VTANLAGIPGL---SIPAGFV-DGLPVGMQILGPQF 444
Cdd:PRK06170  390 EFDVVLCPVTPTPAFPHDHA-PDPLERRI-DIdgvsypYWdqlVWAGLATLPGLpatAIPIGLSaTGLPVGVQIVGPAL 466
PRK12470 PRK12470
amidase; Provisional
 21-452 1.25e-48

amidase; Provisional


Pssm-ID: 171524 [Multi-domain]  Cd Length: 462  Bit Score: 172.76  E-value: 1.25e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  21 SCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEIDRGFR--ERKPLLGIPIALKDLYCTKGIKKTAGSKVlENYIP 98
Cdd:PRK12470   24 TAPMLLEVYLQRIERLDSHLRAYRVVLFDRARAEAEAAQQRLDagERLPLLGVPIAIKDDVDVAGEVTTYGSAG-HGPAA 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  99 VYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRL 178
Cdd:PRK12470  103 TSDAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWDPNRTPGGSSGGSAAAVAAGLAPVALGSDGGGSIRI 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 179 PASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTagfdpkdaTSSNKPVEDYLEGirGNRGTRRI 258
Cdd:PRK12470  183 PSTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLLDAT--------TTVPGPEGEFVAA--AAREPGRL 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 259 RIGLPKEyFGEGLDARIKEKILGAL----GVLEDLGAKIIEVSlPHTKYALAAYYiiqpaevssnLARY-DGIRFGNDRD 333
Cdd:PRK12470  253 RIALSTR-VPTPLPVRCGKQELAAVhqagALLRDLGHDVVVRD-PDYPAATYANY----------LPRFfRGISDDADAQ 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 334 KFGD--EAKRRIM--LGTYIlSAGYYDAYylKAMKVRtLIKRdFNEVFKKVDVLISPVSPNPPFKLGE-----KVNDPMQ 404
Cdd:PRK12470  321 AHPDrlEARTRAIarLGSFF-SDRRMAAL--RAAEVV-LSAR-IQSIFDDVDVVVTPGTATGPSRIGAyqrrgAVSTLLL 395

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1279226875 405 MYLADIYTVTANLAGIPGLSIPAGF-VDGLPVGMQILGPQFSEKMLFQV 452
Cdd:PRK12470  396 VVQRVPYFQVWNLTGQPAAVVPWDFdGDGLPMSVQLVGRPYDEATLLAL 444
PRK06828 PRK06828
amidase; Provisional
 5-460 8.13e-48

amidase; Provisional


Pssm-ID: 180715 [Multi-domain]  Cd Length: 491  Bit Score: 171.54  E-value: 8.13e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   5 ELTIKEAREGLKKKQFSCLELVKSCLEQI---NKTNSKLNSFITVcEEEATEKAVEIDRgfrERK------PLLGIPIAL 75
Cdd:PRK06828   12 ELTIHDIQTAMEDGKLTSKELVMYYLHRIakyDQDGPKINSILEI-NPDAIFIAEALDH---ERKikgvrgPLHGIPVLL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  76 KDLYCTKG-IKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGAS-----GENSDFGPTRNPWN---LER 146
Cdd:PRK06828   88 KDNIETNDsMHTSAGTIALEQHISSEDAFLVTKLREAGAVILGKANMTELANFMSfemwaGYSARGGQTINPYGtgeDDM 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 147 TPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGV 226
Cdd:PRK06828  168 FVGGSSTGSAIAVAANFTVVSVGTETDGSILSPAVQNSVVGIKPTVGLISRRGIIPFTYSQDTAGPFARTVTDAAILLGS 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 227 TAGFDPKD---ATSSNKPVEDYLEGIRGNrGTRRIRIGL----PKEYFGEGLDARIKEKilGALGVLEDLGAKIIE---- 295
Cdd:PRK06828  248 LTGVDEKDvvtHKSEGIAEHDYTKYLDAN-GLNGAKIGVynnaPKEYYESGEYDEKLFK--ETIEVLRSEGATVVEdidi 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 296 ----------VSLPHTKYALAAYYIIQPAEVSSNlARYDGIRFgNDRD-----KFGDEA-KRRIMLGTYILSAGYYDAyy 359
Cdd:PRK06828  325 psfhrewswgVLLYELKHSLDNYLSKLPSTIPVH-SISELMEF-NENIaeralKYGQTKlERRKDFPNTLRNPEYLNA-- 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 360 lKAMKVRTLIKRDFNEVFKK--VDVLISPVSpnppfkLGekvndpmqmyladiYTVTANlAGIPGLSIPAGFVD-GLPVG 436
Cdd:PRK06828  401 -RLEDIYFSQEQGIDFALEKynLDAILFPSY------IG--------------STICAK-AGYPSIAIPAGYMEgGRPFG 458

                         490       500
                  ....*....|....*....|....
gi 1279226875 437 MQILGPQFSEKMLFQVGKIYEQST 460
Cdd:PRK06828  459 ITLASTAFSEGTLIKLAYAFEQAT 482
PRK08186 PRK08186
allophanate hydrolase; Provisional
 6-453 1.01e-47

allophanate hydrolase; Provisional


Pssm-ID: 236177 [Multi-domain]  Cd Length: 600  Bit Score: 173.10  E-value: 1.01e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   6 LTIKEAREGLKKKQFSCLELVKSCLEQINkTNSKLNSFIT-VCEEEATEKAVEIDRGFRERKPLLGIPIALKDLYCTKGI 84
Cdd:PRK08186    7 LTLASLRAAYRAGTLTPRAVVAALYARIA-AVDDPEVWIHlRPEADLLAQAAALEARDPAALPLYGVPFAVKDNIDVAGL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  85 KKTAGSKVLEnYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADEC 164
Cdd:PRK08186   86 PTTAACPAFA-YTPERDATVVARLRAAGAIVIGKTNLDQFATGLVGTRSPYGAVRNAFDPEYVSGGSSSGSAVAVALGLV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 165 LAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSNKPVEd 244
Cdd:PRK08186  165 SFALGTDTAGSGRVPAAFNNIVGLKPTLGLLSTRGVVPACRTLDCVSVFALTVDDADAVLAVMAGFDPADPYSRANPAD- 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 245 ylegiRGNRGTRRIRIGLPK----EYFGEGLDARIKEKilgALGVLEDLGAKIIEVSL-PHTKYALAAYYIIQPAEvssn 319
Cdd:PRK08186  244 -----APAALPAGPRVGVPRaaqlEFFGDAEAEAAFAA---ALARLEALGAELVEIDFsPFLEAARLLYEGPWVAE---- 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 320 laRYDGIR-FGNDRDKFGDEAKRRImlgtyILSAGYYDAY-YLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPfKLGE 397
Cdd:PRK08186  312 --RYAAVGeFLEAHPDAVDPVVRGI-----IAGAAAFSAAdAFRALYRLAELRRAAEAVLAGIDALLVPTAPTHP-TIAE 383

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1279226875 398 KVNDPM----QMylaDIYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVG 453
Cdd:PRK08186  384 VAADPIglnsRL---GTYTNFVNLLDLCALAVPAGFRaDGLPFGVTLIAPAFADQALADLA 441
PRK06707 PRK06707
amidase; Provisional
 5-460 6.15e-42

amidase; Provisional


Pssm-ID: 235855 [Multi-domain]  Cd Length: 536  Bit Score: 156.22  E-value: 6.15e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   5 ELTIKEAREGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCE--EEATEKAVEID--RGFRERKPLLGIPIALKD-LY 79
Cdd:PRK06707   70 NATVDELQKMIDDGKLSYEELTSIYLFRIQEHDQNGITLNSVTEinPNAMEEARKLDqeRSRNKKSNLYGIPVVVKDnVQ 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  80 CTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAH-----GASGENSDFGPTRNPWN-LERTPGGSSS 153
Cdd:PRK06707  150 TAKVMPTSAGTYVLKDWIADQDATIVKQLKEEGAFVLGKANMSEWANylsftMPSGYSGKKGQNLNPYGpIKFDTSGSSS 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 154 GSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPK 233
Cdd:PRK06707  230 GSATVVAADFAPLAVGTETTGSIVAPAAQQSVVGLRPSLGMVSRTGIIPLAETLDTAGPMARTVKDAATLFNAMIGYDEK 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 234 DATSSNKP---VEDYLEGIRGNrGTRRIRIGLpkEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPHT--------- 301
Cdd:PRK06707  310 DVMTEKVKdkeRIDYTKDLSID-GLKGKKIGL--LFSVDQQDENRKAVAEKIRKDLQDAGAILTDYIQLNNggvdnlqtl 386

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 302 ----KYALAAYYIIQ---PAEVSSNLARYdgirfgNDRDKfgdeaKRRIMLGTYILSAGyydayylkamkVRTLIKRDFN 374
Cdd:PRK06707  387 eyefKHNVNDYFSQQknvPVKSLEEIIAF------NKKDS-----KRRIKYGQTLIEAS-----------EKSAITKDEF 444

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 375 EvfKKVDVLISPVSPNPPFKLGEKVNDPMQMYLADIYTVTAnLAGIPGLSIPAGF-VDGLPVGMQILGPQFSEKMLFQVG 453
Cdd:PRK06707  445 E--KVVQTSQENAKKELDRYLVEKGLDALVMINNEEVLLSA-VAGYPELAVPAGYdNNGEPVGAVFVGKQFGEKELFNIG 521


                  ....*..
gi 1279226875 454 KIYEQST 460
Cdd:PRK06707  522 YAYEQQS 528
PRK07056 PRK07056
amidase; Provisional
 7-299 1.02e-41

amidase; Provisional


Pssm-ID: 235921 [Multi-domain]  Cd Length: 454  Bit Score: 153.94  E-value: 1.02e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   7 TIKEAREGLKKKQFSCLELVKSCLEQI-NKTNSKLNSFITVCEEEATEKAVEIDRGFR---ERKPLLGIPIALKDLYCTK 82
Cdd:PRK07056    7 TLAALAADLAAGRTTSRALVEAALARIaDPAGEGARVFTHVDADAARAAADAADALRAagaAPSPLAGIPVSVKDLFDVA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  83 GIKKTAGSKVLENYIP-VYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWN----LERTPGGSSSGSAV 157
Cdd:PRK07056   87 GQVTRAGSRVLADAPPaAADAPAVARLRRAGAVLIGRTNMTEFAFSGLGLNPHYGTPRNPWRrdvgDGRIPGGSSSGAAV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 158 AAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPkdATS 237
Cdd:PRK07056  167 SVADGMAAAALGTDTGGSIRIPAALCGLTGFKPTARRVPLQGAVPLSTTLDSIGPLARSVACCALVDAVLAGEEP--VVP 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279226875 238 SNKPVEDYlegirgnrgtrriRIGLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLP 299
Cdd:PRK07056  245 AARPLEGL-------------RLAVPTTVVLDGLDATVAAAFERALKRLSAAGAIIEEIAFP 293
PRK06102 PRK06102
amidase;
23-443 1.28e-39

amidase;


Pssm-ID: 235698 [Multi-domain]  Cd Length: 452  Bit Score: 148.26  E-value: 1.28e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  23 LELVKSCLEQINKTNSKlNSFITVCEEEATEKAVEIDRGFRERKPLL---GIPIALKDLYCTKGIKKTAGSKVLENYIP- 98
Cdd:PRK06102   23 VQVAEQALDAIASYADQ-AVFISLTEERAMREAEASSARWRAGRSLGlldGIPIAWKDLFDVAGSVTTAGSVVLANAAPa 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  99 VYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWN--LERTPGGSSSGSAVAAAADECLAAMGTDTGGSV 176
Cdd:PRK06102  102 SRDAAVVALLARAGMVSIGRTNMSEFAFSGLGLNPHYGTPVNPRStdVPRIPGGSSSGSAVAVAAGLVPVAMGTDTGGSV 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 177 RLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDS----ALILGVTAgfdpkdATSSNKPVEDylegirgn 252
Cdd:PRK06102  182 RIPAAFNGLVGYKATRGRYSMDGVFPLAKSLDSLGPLCRSVRDAvwidAAMRGLTA------PDVVRRPLAG-------- 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 253 rgtrrIRIGLPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPH--------TKY----ALAAYYIIQPAEVSSNL 320
Cdd:PRK06102  248 -----LRLVVPETVVFDDAEPGVRAAFEAAVERLQAAGALVERQAFPAfqeildliARHgwlvTAEAFALHQERLDGPDA 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 321 ARYDgirfgnDRDKFGDEAKRRIMLGTYIlsAGYYDAYYLKAMKVRTLIKRdfnevfkkvdVLISPVSPN--PPfkLGEK 398
Cdd:PRK06102  323 ARMD------PRVVKRTRLGRKITASDYI--ALLEARERLIAQVTRELGGA----------LLATPTVAHvaPP--LAPL 382

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 1279226875 399 VNDP---MQMYLADI-YTVTANLAGIPGLSIPAGFVD-GLPVGMQILGPQ 443
Cdd:PRK06102  383 EADDdlfFATNLKTLrNTMPGNFLDMCGVSLPCGTGAaGMPVGLLLSAPA 432
PRK08310 PRK08310
amidase; Provisional
 67-442 4.55e-39

amidase; Provisional


Pssm-ID: 181375 [Multi-domain]  Cd Length: 395  Bit Score: 145.51  E-value: 4.55e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  67 PLLGIPIALKDLYCTKGIKKTAGS--KVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNL 144
Cdd:PRK08310   25 PLAGLRFAVKDVFDVAGYVTGCGNpdWLAESPVATRTAPAVEKLLAAGARFVGKTQTDELAFSLNGQNAHYGTPVNPAAP 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 145 ERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALIL 224
Cdd:PRK08310  105 DRVPGGSSSGSAAAVAGGLADFALGTDTGGSVRAPASFCGLYGLRPTHGRISLEGVMPLAPSFDTVGWFARDIALLERVG 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 225 GVTAGFDPKDatssnkpvedylegirgnrGTRRIRIGLPKEYFGEgLDARIKEKILGALGVLEDLGAKIIEVSLPhtKYA 304
Cdd:PRK08310  185 EVLLGDDAQE-------------------FPLTQRLLIPVDLFAL-LDPAVRAALEAALARLRPHLGPAKPASVP--PLS 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 305 LAAYY----IIQPAEVssnlARYDGIRFGNDRDKFGDEAKRRimlgtYILSAGYYDAYYLKAMKVRTLIKRDFNEVFKKV 380
Cdd:PRK08310  243 LDEWYeafrVLQAAEA----WETHGAWISSGNPQLGPGVADR-----FAAGAEVTADQVEAARARRAAFARELAALLGPD 313

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1279226875 381 DVLISPVSPNPPFKLGEKVNDpMQMYLADIYTVT--ANLAGIPGLSIPAGFVDGLPVGMQILGP 442
Cdd:PRK08310  314 AVLLLPTVPGAAPLRGAPFEA-LEAYRERALRLLciAGLAGLPQISLPLASVDGAPFGLSLIGP 376
PRK05962 PRK05962
amidase; Validated
 43-453 2.48e-36

amidase; Validated


Pssm-ID: 168315 [Multi-domain]  Cd Length: 424  Bit Score: 138.76  E-value: 2.48e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  43 FITVCEEEATEKAVEIDRGFRERK---PLLGIPIALKDLYCTKGIKKTAGSKVLENYIPVY-DATVVDKLKNAGAIIIGK 118
Cdd:PRK05962   18 FSKLYAERARAEADAADARRRAGRslgPLDGRIVSIKDLFDVAGEPTLAGSVIRRDAPPAGaDALIVQRLRNAGAVIIGK 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 119 TNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRY 198
Cdd:PRK05962   98 THMTEFAFTPVGLNPHYGEPGNAIDPARIPGGSSSGAAVSVAEGTSEIAIGSDTGGSVRIPAALNGLVGFKPTARRIPLE 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 199 GVVAMASSLDCMGHLTKTVEDSALILGVTAGFDPKDATSSnkPVEDylegirgnrgtrrIRIGLPKEYFGEGLDARIKEK 278
Cdd:PRK05962  178 GAFPLSPSLDSIGPLARTVADCAAADAVMAGEKPIPLEVL--PVAG-------------LRIGLPKGYLLADMEPDVAAA 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 279 ILGALGVLEDLGAKIIEVS----LPHTKYALAAYYI--IQPAEVSSNLARYDGIRFgNDRDKFgdEAKRRIMLGtyilsa 352
Cdd:PRK05962  243 FEASLAALEKAGARIADLAiddlIARLAEATRIGSIagIEASHIHADWLADLDANV-DIRVKR--PLSRRIKVP------ 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 353 gyyDAYYLKAMKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLGEKVNDPMQ------MYLADiyTVTANLAGIPGLSIP 426
Cdd:PRK05962  314 ---LEAYHRLMRTRAALARAMDERLAGFDMFALPATPIVAPTIASVSEDEEEydrvenLLLRN--TQVANQFDLCSITLP 388

                         410       420
                  ....*....|....*....|....*...
gi 1279226875 427 -AGFvdGLPVGMQILGPQFSEKMLFQVG 453
Cdd:PRK05962  389 mPGM--ALPAGLMLTARNGSDRRLLAAA 414
PRK07869 PRK07869
amidase; Provisional
 13-457 9.08e-31

amidase; Provisional


Pssm-ID: 181154 [Multi-domain]  Cd Length: 468  Bit Score: 123.94  E-value: 9.08e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  13 EGLKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAveiDRGFRERKPLLGIPIALKDLYCTKGIKKTAGSKV 92
Cdd:PRK07869   22 EAIRAGRVSAAEVVEAAIARAEAVNPALNALAYAAFDRARDRA---ARPGSQGGFFSGVPTFIKDNVDVAGLPTMHGSDA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  93 LENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDT 172
Cdd:PRK07869   99 WTPRPAKADSDFARQFLATGLISLGKTQLPEFGFSASTEHPRLGPVRNPWNTDYSAGASSGGSAALVAAGVVPIAHANDG 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 173 GGSVRLPASFCNVVGLKPTYGRV-----SRYGVVAMASSldcmGHLTKTVEDSALILgvtagfdpKDATSSNK-----PV 242
Cdd:PRK07869  179 GGSIRIPAACCGLVGLKPSRGRLpldpeLRRLPVNIVAN----GVLTRTVRDTAAFY--------REAERYYRnpklpPI 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 243 EDylegIRGNrGTRRIRIGLPKE-YFGEGLDARIKEKILGALGVLEDLGAKIIEVSLPHTK---------YALAAYYIIQ 312
Cdd:PRK07869  247 GD----VTGP-GKQRLRIAVVTDsVTGREADPEVREAVLATARLLEELGHRVEPVDLPVPAsfvddfllyWGFLAFALVR 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 313 PAEV----SSNLARYDGIRFGNDRdkfgdEAKRRIM-LGTYIlsagyydayylkaMKVRTLIkRDFNEVFKKVDVLISPV 387
Cdd:PRK07869  322 GGRRtfgpSFDRTRLDNLTLGLAR-----HARRNLHrLPLAI-------------ARLRRLR-RVYARFFGTYDVVLTPT 382

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279226875 388 SPNPPFKLG--------EKVNDPMQMYLAdiYTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKMLFQVGkiYE 457
Cdd:PRK07869  383 LAHTTPEIGyldptqdfDTVLDRLISYVA--FTPLQNATGEPAISLPLGQSsDGLPVGMMFSADVGDEATLLELA--YE 457
PRK11910 PRK11910
amidase; Provisional
 5-460 1.79e-30

amidase; Provisional


Pssm-ID: 183377 [Multi-domain]  Cd Length: 615  Bit Score: 124.37  E-value: 1.79e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   5 ELTIKEAREGL-------------KKKQFSCLELVKSCLEQINKTNSK---LNSfITVCEEEATEKAVEIDRGFRERKP- 67
Cdd:PRK11910  151 DLAVLEAKEPLiigadvtklqqliATKQLSYKELAGIYLNRIKKYDQNglnLNA-ITEINPTIIAEAEQLDKENTTNKSa 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  68 LLGIPIALKDLYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHG-----ASGENSDFGPTRNPW 142
Cdd:PRK11910  230 LYGMPVLLKDNIGTKELPTSAGTVALKDWVIGKDATIVENLKANGALILGKTNMSEWAAGmdedlPNGYSGKKGQSKNPY 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 143 NLERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSAL 222
Cdd:PRK11910  310 SSNLDPSGSSSGSATAATSDFAAIAIGTETNGSIITPASAQSAVGYKPSQGLVNNKGIIPLSSRFDTPGPLTRTVNDAYL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 223 ILGVTAGfdpkdaTSSNKPV-EDYLEGIR--------GNRGT---RRIRIGLPKEyfgeglDARIKEKIlgALGVLEDLG 290
Cdd:PRK11910  390 TTNALTN------TTSNPPLsTDALKGKRiglladgeSNEETaviKKIKLDLQKA------GATIIEGI--AVGEFEQKD 455

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 291 AKIIEVSLPHTKYALAAYYIIQPAEVS----------SNLARydGIRFGNDRdkfgdeakrrimlgtyILSAGYYDAYYL 360
Cdd:PRK11910  456 TDYASLLNADFKHDLNQFLQVNHSPMStlesiiqfnqTNPTR--NMKYGQSE----------------LVKSQQSTITKQ 517

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 361 KAMKVRT-LIKRDFNEV-----FKKVDVLISpvspnppFKLGEKVndpmqMYLADIytvtanlAGIPGLSIPAGFVD--G 432
Cdd:PRK11910  518 QADNLASnLIQSSQNELdsvlqKDKLDAVVT-------IGMGGSV-----MFLAPI-------AGNPELTIPAGYDEesN 578

                         490       500
                  ....*....|....*....|....*...
gi 1279226875 433 LPVGMQILGPQFSEKMLFQVGKIYEQST 460
Cdd:PRK11910  579 QPISLTFITARNSDKILLNMGYAYEQQS 606
PRK06529 PRK06529
amidase; Provisional
 15-459 3.02e-27

amidase; Provisional


Pssm-ID: 180608 [Multi-domain]  Cd Length: 482  Bit Score: 113.76  E-value: 3.02e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  15 LKKKQFSCLELVKSCLEQINKTNSKLNSFITVCEEEATEKAVEidRGFrERKPLLGIPIALKDL-YCTKGIKKTAGSKVL 93
Cdd:PRK06529   13 VQQGQVTPLELVTQAIYKAKKLNPTLNAIVSERYEEALEEAKQ--RDF-SGKPFAGVPIFLKDLgQELKGQLSTSGSRLF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  94 ENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNLERTPGGSSSGSAVAAAADECLAAMGTDTG 173
Cdd:PRK06529   90 KNYQATKTDLYVKRLEDLGFIILGRSNTPEFGFKNISDSSLHGPVNLPFDNSRNAGGSSGGAAALVSSGIVALAAASDGG 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 174 GSVRLPASFCNVVGLKPTYGRV----SRYGVVAMASSldcmgH--LTKTVEDSALIL------GVTAGFdPKdATSSNKP 241
Cdd:PRK06529  170 GSIRIPASFNGLIGLKPSRGRIpvgpGSYRGWQGASV-----HfaLTKSVRDTRRLLyylqmyQMESPF-PL-ATLSKES 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 242 VEDYLEgirgnrgtRRIRIG-LPKEYFGEGLDARIKEKILGALGVLEDLGAKIIEVS-LP-HTKYALAAYYIIQPAEVSs 318
Cdd:PRK06529  243 LFQSLQ--------RPLKIAfYQRSPDGSPVSLDAAKALKQAVTFLREQGHEVVELEeFPlDMTEVMRSYYIMNSVETA- 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 319 nlARYDGIR--FGNDRDKFGDEAKRRIML--GTYILSAGYYDAyyLKAMKVRTLIKRDFNEvfkKVDVLISPVSPNPPFK 394
Cdd:PRK06529  314 --AMFDDIEdaLGRPMTKDDMETMTWAIYqsGQDIPAKRYSQV--LQKWDTYSATMASFHE---TYDLLLTFTTNTPAPK 386

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 395 LGEKVNDP-MQMYLADI------------------------YTVTANLAGIPGLSIPAGFV-DGLPVGMQILGPQFSEKM 448
Cdd:PRK06529  387 HGQLDPDSkLMANLAQAeifsseeqqnlvetmfekslaitpYTALANLTGQPAISLPTYETkEGLPMGVQLIAAKGREDL 466

                         490
                  ....*....|.
gi 1279226875 449 LFQVGKIYEQS 459
Cdd:PRK06529  467 LLGIAEQFEAA 477
PLN02722 PLN02722
indole-3-acetamide amidohydrolase
 67-452 4.08e-22

indole-3-acetamide amidohydrolase


Pssm-ID: 166363  Cd Length: 422  Bit Score: 98.04  E-value: 4.08e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  67 PLLGIPIALKDLYCTKGIKKTAGSK--VLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASGENSDFGPTRNPWNL 144
Cdd:PLN02722   26 PLHGLTFAVKDIFDVEGYVTGFGNPdwARTHSAATSTAPAVLAVLRGGATCVGKTIMDEMAYSINGENAHYGTPTNPIAP 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 145 ERTPGGSSSGSAVAAAADECLAAMGTDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKtveDSALIL 224
Cdd:PLN02722  106 DRVPGGSSSGSAVAVGAKLVDFSLGTDTGGSVRVPASYCGIFGFRPSHGAVSTVGVIPMAQSFDTVGWFAR---DPVILK 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 225 GVTAGFDPKDATSSNKP-----VEDYLEgirgnrgtrriRIGLPKEYFGEGLDARIkEKILGALGVLE--DLGaKIIEVS 297
Cdd:PLN02722  183 RVGHVLLQQPDVNPIKPsqiiiAEDCFQ-----------LSSIPHDRLVQVLVKSV-EKLFGGGDIVKhvNLG-DYVEDK 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 298 LPHTKYALAA------YYIIQPAEVSSN---LARYD-----GIRFGNDRDKFGDEAKRRI--MLGTyilSAGYYDAYYlk 361
Cdd:PLN02722  250 VPSLKHFMSKeikeqeYNIPSLAALSSAmrlLQRYEfkinhGEWITAVKPEFGPGISERIweAVRT---TEEKIDACQ-- 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 362 amKVRTLIKRDFNEVFKKVDVLISPVSPNPPFKLGEKVNdPMQMYLADIYTVTAnLAGIPG---LSIPAGFVDGLPVGMQ 438
Cdd:PLN02722  325 --SVKTELRAALTTLLGEFGVLVIPTVPGPPPKLQADPT-TLESFRARAFSLLS-IAGVSGfcqVSIPLGLHDNLPVSVS 400

                         410
                  ....*....|....
gi 1279226875 439 ILGPQFSEKMLFQV 452
Cdd:PLN02722  401 LLAKHGSDGFLLNL 414
PRK06565 PRK06565
amidase; Validated
 5-299 2.24e-17

amidase; Validated


Pssm-ID: 180626  Cd Length: 566  Bit Score: 84.44  E-value: 2.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875   5 ELTIKEAREGLKKKQFSCLELVKSCLEQIN-----KTNSKLNSfITVCEEEATEKAVEID----RGfRERKPLLGIPIAL 75
Cdd:PRK06565    6 EVSIAELRAALESGRTTAVELVKAYLARIDaydgpATGTALNA-VVVRNPDALKEAEASDarraRG-ETLGPLDGIPYTA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875  76 KDLYCTKGIKKTAGSKVLENYIPVYDATVVDKLKNAGAIIIGKTNCDAWAHGASgENSDFGPTRNPWNLE--RTPGGSSS 153
Cdd:PRK06565   84 KDSYLVKGLTAASGSPAFKDLVAQRDAFTIERLRAAGAICLGKTNMPPMANGGM-QRGVYGRAESPYNAAylTAPFASGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 154 GSAVAAAADECLAAMG--TDTGGSVRLPASFCNVVGLKPTYGRVSRYGVVAMASSLDCMGHLTKTVEDSALILGVTAGFD 231
Cdd:PRK06565  163 SNGAGTATAASFSAFGlaEETWSSGRGPASNNGLCAYTPSRGVISVRGNWPLTPTMDVVVPYARTMADLLEVLDVIVADD 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226875 232 PKD--------------ATSSNKPvEDYLEGIRGNRGTRRIRIGLPKEYFGEGLDARIKEK--ILGALG----------- 284
Cdd:PRK06565  243 PDTrgdlwrlqpwvpipKASEVRP-ASYLALAAGADALKGKRFGVPRMYINADPDAGTSENpgIGGPTGqrihtrpsvid 321

                         330       340
                  ....*....|....*....|..
gi 1279226875 285 -------VLEDLGAKIIEVSLP 299
Cdd:PRK06565  322 lweaarrALEAAGAEVIEVDFP 343
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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