NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1279226881|gb|PJE68478|]
View 

hypothetical protein COU94_01640 [Candidatus Shapirobacteria bacterium CG10_big_fil_rev_8_21_14_0_10_38_8]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Glucodextran_B super family cl07671
Glucodextranase, domain B; Members of this family adopt a structure consisting of seven ...
 153-232 5.99e-09

Glucodextranase, domain B; Members of this family adopt a structure consisting of seven/eight-strand antiparallel beta-sheets, in a Greek-key topology, similar to the immunoglobulin beta-sandwich fold. They act as cell wall anchors, where they interact with the S-layer present in the cell wall of Gram-positive bacteria by hydrophobic interactions. In glucodextranase, Domain B is buried in the S-layer, and a flexible linker located between domain B and the catalytic unit confers motion to the catalytic unit, which is capable of efficient hydrolysis of the substrates located close to the cell surface.


The actual alignment was detected with superfamily member pfam09136:

Pssm-ID: 430428 [Multi-domain]  Cd Length: 83  Bit Score: 51.72  E-value: 5.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226881 153 PTLIIDKPADNSQfsgSNQRNLSISGK-TDPDC-TISLNDHLAIMGKDGNFSYTFTLNEGDNALKIVATDQAGNQTEKDL 230
Cdd:pfam09136   1 PELTITSPADGLT---TNRETVTVTGTvADANLdSVTVNGIAATVYKDGTFSKRILLVEGENVITVIAVDSAGNTVTKTI 77


                  ..
gi 1279226881 231 TI 232
Cdd:pfam09136  78 TV 79
 
Name Accession Description Interval E-value
Glucodextran_B pfam09136
Glucodextranase, domain B; Members of this family adopt a structure consisting of seven ...
 153-232 5.99e-09

Glucodextranase, domain B; Members of this family adopt a structure consisting of seven/eight-strand antiparallel beta-sheets, in a Greek-key topology, similar to the immunoglobulin beta-sandwich fold. They act as cell wall anchors, where they interact with the S-layer present in the cell wall of Gram-positive bacteria by hydrophobic interactions. In glucodextranase, Domain B is buried in the S-layer, and a flexible linker located between domain B and the catalytic unit confers motion to the catalytic unit, which is capable of efficient hydrolysis of the substrates located close to the cell surface.


Pssm-ID: 430428 [Multi-domain]  Cd Length: 83  Bit Score: 51.72  E-value: 5.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226881 153 PTLIIDKPADNSQfsgSNQRNLSISGK-TDPDC-TISLNDHLAIMGKDGNFSYTFTLNEGDNALKIVATDQAGNQTEKDL 230
Cdd:pfam09136   1 PELTITSPADGLT---TNRETVTVTGTvADANLdSVTVNGIAATVYKDGTFSKRILLVEGENVITVIAVDSAGNTVTKTI 77


                  ..
gi 1279226881 231 TI 232
Cdd:pfam09136  78 TV 79
Ca_tandemer NF033510
Ca2+-stabilized adhesin repeat; This repeat is found in proteins such as the ...
 143-226 5.22e-05

Ca2+-stabilized adhesin repeat; This repeat is found in proteins such as the biofilm-associated protein Bap of Acinetobacter baumannii (which can exceed 8000 amino acids in length), the calcium-stabilized ice-binding adhesin of the Antarctic bacterium Marinomonas primoryensis, and the giant calcium-binding adhesin SiiE of Salmonella enterica.


Pssm-ID: 411149 [Multi-domain]  Cd Length: 97  Bit Score: 41.12  E-value: 5.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226881 143 TLNILLKTTLPTLIIDKPADNSQFSGSNQ-RNLSISGKTDPD----CTISLNDHL--AIMGKDGNFSYT------FTLNE 209
Cdd:NF033510    1 THPVTVDTTAPALTINPVAGDDVLNAAEQgQGLTLSGTTTAEagqtVTVTLNGKTytATVDADGSWSVTvpaadlAALAD 80

                          90
                  ....*....|....*..
gi 1279226881 210 GDNALKIVATDQAGNQT 226
Cdd:NF033510   81 GTYTVTVTVTDAAGNTS 97
 
Name Accession Description Interval E-value
Glucodextran_B pfam09136
Glucodextranase, domain B; Members of this family adopt a structure consisting of seven ...
 153-232 5.99e-09

Glucodextranase, domain B; Members of this family adopt a structure consisting of seven/eight-strand antiparallel beta-sheets, in a Greek-key topology, similar to the immunoglobulin beta-sandwich fold. They act as cell wall anchors, where they interact with the S-layer present in the cell wall of Gram-positive bacteria by hydrophobic interactions. In glucodextranase, Domain B is buried in the S-layer, and a flexible linker located between domain B and the catalytic unit confers motion to the catalytic unit, which is capable of efficient hydrolysis of the substrates located close to the cell surface.


Pssm-ID: 430428 [Multi-domain]  Cd Length: 83  Bit Score: 51.72  E-value: 5.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226881 153 PTLIIDKPADNSQfsgSNQRNLSISGK-TDPDC-TISLNDHLAIMGKDGNFSYTFTLNEGDNALKIVATDQAGNQTEKDL 230
Cdd:pfam09136   1 PELTITSPADGLT---TNRETVTVTGTvADANLdSVTVNGIAATVYKDGTFSKRILLVEGENVITVIAVDSAGNTVTKTI 77


                  ..
gi 1279226881 231 TI 232
Cdd:pfam09136  78 TV 79
Ca_tandemer NF033510
Ca2+-stabilized adhesin repeat; This repeat is found in proteins such as the ...
 143-226 5.22e-05

Ca2+-stabilized adhesin repeat; This repeat is found in proteins such as the biofilm-associated protein Bap of Acinetobacter baumannii (which can exceed 8000 amino acids in length), the calcium-stabilized ice-binding adhesin of the Antarctic bacterium Marinomonas primoryensis, and the giant calcium-binding adhesin SiiE of Salmonella enterica.


Pssm-ID: 411149 [Multi-domain]  Cd Length: 97  Bit Score: 41.12  E-value: 5.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226881 143 TLNILLKTTLPTLIIDKPADNSQFSGSNQ-RNLSISGKTDPD----CTISLNDHL--AIMGKDGNFSYT------FTLNE 209
Cdd:NF033510    1 THPVTVDTTAPALTINPVAGDDVLNAAEQgQGLTLSGTTTAEagqtVTVTLNGKTytATVDADGSWSVTvpaadlAALAD 80

                          90
                  ....*....|....*..
gi 1279226881 210 GDNALKIVATDQAGNQT 226
Cdd:NF033510   81 GTYTVTVTVTDAAGNTS 97
Big_13 pfam19077
Bacterial Ig-like domain; Presumed domain found as tandem repeats of high sequence identity in ...
 151-229 8.40e-04

Bacterial Ig-like domain; Presumed domain found as tandem repeats of high sequence identity in bacterial cell surface proteins.


Pssm-ID: 465968 [Multi-domain]  Cd Length: 102  Bit Score: 37.63  E-value: 8.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279226881 151 TLPTLIID-KPADNSQFSGS----NQRNLSISGKTDPDCTISLNDHLAIMGK--------DGNFSYTFT--LNEGDNALK 215
Cdd:pfam19077   1 TLSIPTIDlAAGSDTGVSDSdnitNDTTPTFTGTNEDGDVVTVTVSIDGNGVtgtatagaDGNWSFTPPaaLADGTYTLT 80

                          90
                  ....*....|....
gi 1279226881 216 IVATDQAGNQTEKD 229
Cdd:pfam19077  81 VTVTDIAGNTATSS 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH