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Conserved domains on  [gi|1279228384|gb|PJE69792.1|]
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adenylate kinase [Candidatus Staskawiczbacteria bacterium CG10_big_fil_rev_8_21_14_0_10_38_10]

Protein Classification

adenylate kinase family protein( domain architecture ID 11426204)

adenylate kinase family protein such as adenylate kinase that catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0019205|GO:0005524|GO:0016310|GO:0006139
PubMed:  2841070|14568537|3023080

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 30-242 8.18e-68

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


:

Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 208.06  E-value: 8.18e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLenfKKHLKIR 109
Cdd:COG0563     3 IILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL---AQPDCAN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAiladEALEWYEWDKNVK---VILLNISRRESYNRLTKRRQCKKCG---HLIpwigeFKKLK---KC 180
Cdd:COG0563    80 GFILDGFPRTVAQA----EALDELLAELGIKldaVIELDVDDEELVERLSGRRVCPNCGatyHVK-----FNPPKvegVC 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279228384 181 DKCGGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:COG0563   151 DKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
 
Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 30-242 8.18e-68

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 208.06  E-value: 8.18e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLenfKKHLKIR 109
Cdd:COG0563     3 IILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL---AQPDCAN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAiladEALEWYEWDKNVK---VILLNISRRESYNRLTKRRQCKKCG---HLIpwigeFKKLK---KC 180
Cdd:COG0563    80 GFILDGFPRTVAQA----EALDELLAELGIKldaVIELDVDDEELVERLSGRRVCPNCGatyHVK-----FNPPKvegVC 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279228384 181 DKCGGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:COG0563   151 DKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk PRK00279
adenylate kinase; Reviewed
 30-243 9.67e-60

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 187.66  E-value: 9.67e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLenfKKHLKIR 109
Cdd:PRK00279    3 LILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERL---AQPDCKN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAiladEALEWYEWDKNVK---VILLNISRRESYNRLTKRRQCKKCGHLipWIGEFKKLK---KCDKC 183
Cdd:PRK00279   80 GFLLDGFPRTIPQA----EALDEMLKELGIKldaVIEIDVPDEELVERLSGRRICPACGRT--YHVKFNPPKvegKCDVC 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 184 GGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAIK 243
Cdd:PRK00279  154 GEELIQRADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 30-243 4.80e-58

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 183.20  E-value: 4.80e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLEnfKKHLKIR 109
Cdd:TIGR01351   2 LVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLT--QNDDNEN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAiladEALEWYEWDKNVKVILLNISRRESYNRLTKRRQCKKCG---HLipwigEFKKLKK--CDKCG 184
Cdd:TIGR01351  80 GFILDGFPRTLSQA----EALDALLEEPIDAVIELDVPDEELVERLSGRRICPSCGrvyHL-----KFNPPKVpgCDDCT 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 185 GE-LITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAIK 243
Cdd:TIGR01351 151 GElLVQREDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 29-234 5.09e-56

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 177.43  E-value: 5.09e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  29 VFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKIlgdVLENFKKHLKI 108
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKL---LKERLKKPDCK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 109 RGFVLDGWTRIIFEAILADEALEwyEWDKNVKVILLNISRRESYNRLTKRRQCKKCGHLIpwigefkKLKKCDKCGGELI 188
Cdd:cd01428    78 KGFILDGFPRTVDQAEALDELLD--EGIKPDKVIELDVPDEVLIERILGRRICPVSGRVY-------HLGKDDVTGEPLS 148

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1279228384 189 TRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDV 234
Cdd:cd01428   149 QRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
32-219 3.16e-44

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 147.07  E-value: 3.16e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  32 IVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHlkiRGF 111
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCK---NGF 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 112 VLDGWTRIIFEAILADEALEW-YEWDknvKVILLNISRRESYNRLTKRRQCKKCG---HLipwigEFKKLK---KCDKCG 184
Cdd:pfam00406  78 LLDGFPRTVPQAEALEELLERgIKLD---YVIEFDVPDEVLVERLTGRRIHPNSGrsyHL-----EFNPPKvpgKDDVTG 149

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1279228384 185 GELITRADDKMESIKKRLEEYKNQTKKAINYYKKQ 219
Cdd:pfam00406 150 EPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 30-242 8.18e-68

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 208.06  E-value: 8.18e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLenfKKHLKIR 109
Cdd:COG0563     3 IILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL---AQPDCAN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAiladEALEWYEWDKNVK---VILLNISRRESYNRLTKRRQCKKCG---HLIpwigeFKKLK---KC 180
Cdd:COG0563    80 GFILDGFPRTVAQA----EALDELLAELGIKldaVIELDVDDEELVERLSGRRVCPNCGatyHVK-----FNPPKvegVC 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279228384 181 DKCGGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:COG0563   151 DKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk PRK00279
adenylate kinase; Reviewed
 30-243 9.67e-60

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 187.66  E-value: 9.67e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLenfKKHLKIR 109
Cdd:PRK00279    3 LILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERL---AQPDCKN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAiladEALEWYEWDKNVK---VILLNISRRESYNRLTKRRQCKKCGHLipWIGEFKKLK---KCDKC 183
Cdd:PRK00279   80 GFLLDGFPRTIPQA----EALDEMLKELGIKldaVIEIDVPDEELVERLSGRRICPACGRT--YHVKFNPPKvegKCDVC 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 184 GGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAIK 243
Cdd:PRK00279  154 GEELIQRADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 30-243 4.80e-58

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 183.20  E-value: 4.80e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLEnfKKHLKIR 109
Cdd:TIGR01351   2 LVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLT--QNDDNEN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAiladEALEWYEWDKNVKVILLNISRRESYNRLTKRRQCKKCG---HLipwigEFKKLKK--CDKCG 184
Cdd:TIGR01351  80 GFILDGFPRTLSQA----EALDALLEEPIDAVIELDVPDEELVERLSGRRICPSCGrvyHL-----KFNPPKVpgCDDCT 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 185 GE-LITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAIK 243
Cdd:TIGR01351 151 GElLVQREDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 29-234 5.09e-56

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 177.43  E-value: 5.09e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  29 VFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKIlgdVLENFKKHLKI 108
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKL---LKERLKKPDCK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 109 RGFVLDGWTRIIFEAILADEALEwyEWDKNVKVILLNISRRESYNRLTKRRQCKKCGHLIpwigefkKLKKCDKCGGELI 188
Cdd:cd01428    78 KGFILDGFPRTVDQAEALDELLD--EGIKPDKVIELDVPDEVLIERILGRRICPVSGRVY-------HLGKDDVTGEPLS 148

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1279228384 189 TRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDV 234
Cdd:cd01428   149 QRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
32-219 3.16e-44

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 147.07  E-value: 3.16e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  32 IVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHlkiRGF 111
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCK---NGF 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 112 VLDGWTRIIFEAILADEALEW-YEWDknvKVILLNISRRESYNRLTKRRQCKKCG---HLipwigEFKKLK---KCDKCG 184
Cdd:pfam00406  78 LLDGFPRTVPQAEALEELLERgIKLD---YVIEFDVPDEVLVERLTGRRIHPNSGrsyHL-----EFNPPKvpgKDDVTG 149

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1279228384 185 GELITRADDKMESIKKRLEEYKNQTKKAINYYKKQ 219
Cdd:pfam00406 150 EPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
PRK14530 PRK14530
adenylate kinase; Provisional
 26-242 5.78e-43

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 144.93  E-value: 5.78e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  26 NPKVfIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRArQKIGDFTGKKLI-----QAMGRGELAPSFVIVKILGDVLE 100
Cdd:PRK14530    3 QPRI-LLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRA-NKQMDISDMDTEydtpgEYMDAGELVPDAVVNEIVEEALS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 101 NFKkhlkirGFVLDGWTRIIFEAiladEALEWYEwDKNVkVILLNISRRESYNRLTKRRQCKKCG---HLipwigEFKKL 177
Cdd:PRK14530   81 DAD------GFVLDGYPRNLEQA----EYLESIT-DLDV-VLYLDVSEEELVDRLTGRRVCPDCGanyHV-----EFNQP 143

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1279228384 178 KK---CDKCGGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:PRK14530  144 EEegvCDECGGELIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAI 211
PRK14526 PRK14526
adenylate kinase; Provisional
 30-242 2.47e-36

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 127.66  E-value: 2.47e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  30 FIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHlkiR 109
Cdd:PRK14526    3 LVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNN---D 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 110 GFVLDGWTRIIFEAILADEALEwyewdkNVKVILLNISRRESYNRLTKRRQCKKCGHLIP-WIGEFKKLKKCDKCGGELI 188
Cdd:PRK14526   80 NFILDGFPRNINQAKALDKFLP------NIKIINFLIDEELLIKRLSGRRICKSCNNIFNiYTLPTKEKGICDVCKGDLY 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1279228384 189 TRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:PRK14526  154 QRKDDKEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEVKKKLIEII 207
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 28-242 1.77e-32

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 116.84  E-value: 1.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  28 KVFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLenFKKHLK 107
Cdd:TIGR01360   4 KIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAM--VAALGT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 108 IRGFVLDGWTR-----IIFEAILADEALewyewdknvkVILLNISRRESYNRLTKRrqckkcghlipwigefkklkkcdk 182
Cdd:TIGR01360  82 SKGFLIDGYPRevkqgEEFERRIGPPTL----------VLYFDCSEDTMVKRLLKR------------------------ 127

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 183 cgGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:TIGR01360 128 --AETSGRVDDNEKTIKKRLETYYKATEPVIAYYETKGKLRKINAEGTVDDVFLQVCTAI 185
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 29-240 1.20e-31

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 114.78  E-value: 1.20e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  29 VFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGR-GELAPSFVIVKILGDVLENFKKHlk 107
Cdd:TIGR01359   1 VVFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKREGSENGSLIESYIKeGKIVPSEVTVELLKKAIQEDGSS-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 108 iRGFVLDGWTRiifeailADEALE-WYE---WDKNVK-VILLNISRRESYNRLTKRrqckkcghlipwigefkklkkcdk 182
Cdd:TIGR01359  79 -KKFLIDGFPR-------NEENLEaWEKlmdNKVNFKfVLFFDCPEETMIKRLLKR------------------------ 126

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1279228384 183 cgGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILK 240
Cdd:TIGR01359 127 --GQTSGRVDDNIETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSVEEVFEDVEK 182
PRK14528 PRK14528
adenylate kinase; Provisional
 28-242 1.28e-27

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 104.32  E-value: 1.28e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  28 KVFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHlk 107
Cdd:PRK14528    2 KNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCK-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 108 iRGFVLDGWTRIIFEAILADEALEwyEWDKNV-KVILLNISRRESYNRLTKRrqckkcghlipwigefkklkkcdkcgGE 186
Cdd:PRK14528   80 -NGFLLDGFPRTVEQADALDALLK--NEGKSIdKAINLEVPDGELLKRLLGR--------------------------AE 130

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1279228384 187 LITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:PRK14528  131 IEGRADDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGSLEEVTSLIQKEL 186
PRK14527 PRK14527
adenylate kinase; Provisional
 27-242 1.74e-27

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 104.10  E-value: 1.74e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  27 PKVFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHL 106
Cdd:PRK14527    6 NKVVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 107 KIrgfvLDGWTRIIFEAILADEALEwyEWDKNVK-VILLNISRRESYNRLTKRrqckkcghlipwigefkklkkcdkcgG 185
Cdd:PRK14527   86 VI----FDGFPRTLAQAEALDRLLE--ELGARLLaVVLLEVPDEELIRRIVER--------------------------A 133

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1279228384 186 ELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:PRK14527  134 RQEGRSDDNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGTPDEVYARILKAL 190
PLN02674 PLN02674
adenylate kinase
 28-242 6.87e-27

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 103.81  E-value: 6.87e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  28 KVFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGdvlENFKKHLK 107
Cdd:PLN02674   32 KRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIID---EAMKKPSC 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 108 IRGFVLDGWTRIIFEAILADEALEwYEWDKNVKVILLNISRRESYNRLTKRRQCKKCGHLIPWIGEFKKLKKCDKCGGE- 186
Cdd:PLN02674  109 QKGFILDGFPRTVVQAQKLDEMLA-KQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEp 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1279228384 187 LITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:PLN02674  188 LIQRKDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEVQKAL 243
adk PRK02496
adenylate kinase; Provisional
 31-243 1.09e-26

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 101.75  E-value: 1.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  31 IIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVivkILGDVLENFKKHLKIRG 110
Cdd:PRK02496    5 IFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQL---VLDLVQERLQQPDAANG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 111 FVLDGWTRIIFEAILADEALE----WYEWdknvkVILLNISRRESYNRLTKRrqckkcghlipwigefkklkkcdkcgge 186
Cdd:PRK02496   82 WILDGFPRKVTQAAFLDELLQeigqSGER-----VVNLDVPDDVVVERLLAR---------------------------- 128

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1279228384 187 liTRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAIK 243
Cdd:PRK02496  129 --GRKDDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQSVEAVTTELKAALA 183
PRK14531 PRK14531
adenylate kinase; Provisional
 31-242 5.33e-26

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 99.89  E-value: 5.33e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  31 IIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKIlgdvLENFKKHLKIRG 110
Cdd:PRK14531    6 LFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAI----VESQLKALNSGG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 111 FVLDGWTRIIFEAiladEALE--WYEWDKNVK-VILLNISRRESYNRLTKRrqckkcghlipwigefkklkkcdkcggel 187
Cdd:PRK14531   82 WLLDGFPRTVAQA----EALEplLEELKQPIEaVVLLELDDAVLIERLLAR----------------------------- 128

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1279228384 188 iTRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:PRK14531  129 -GRADDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQSVEAQGSIEAITERIEKVL 182
PRK14532 PRK14532
adenylate kinase; Provisional
 31-243 6.25e-26

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 99.90  E-value: 6.25e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  31 IIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKkhlKIRG 110
Cdd:PRK14532    4 ILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAE---AAGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 111 FVLDGWTRIIFEAiladEALEWYEWDKNVK---VILLNISRRESYNRLTKRrqckkcghlipwigefkklkkcdkcgGEL 187
Cdd:PRK14532   81 AIFDGFPRTVAQA----EALDKMLASRGQKidvVIRLKVDDEALIERIVKR--------------------------FEE 130

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1279228384 188 ITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAIK 243
Cdd:PRK14532  131 QGRPDDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDGMGSIEAVAASIDAALE 186
PRK14529 PRK14529
adenylate kinase; Provisional
 31-240 7.42e-25

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 97.87  E-value: 7.42e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  31 IIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHlkirG 110
Cdd:PRK14529    4 LIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDGKN----G 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 111 FVLDGWTRIIFEAILADEALEwyewDKNVK---VILLNISRRESYNRLTKRRQCKK-CGHliP---WIGEFKKL-KKCDK 182
Cdd:PRK14529   80 WLLDGFPRNKVQAEKLWEALQ----KEGMKldyVIEILLPREVAKNRIMGRRLCKNdNNH--PnniFIDAIKPDgDVCRV 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1279228384 183 CGGELITRADDKME-SIKKRLEEYKNQ---TKKAINYYKKQG-----RLIEINGGQSIEDVFKDILK 240
Cdd:PRK14529  154 CGGELSTRADDQDEeAINKRHDIYYDTetgTLAAAYFFKDLAakgstKYIELDGEGSIDEIKETLLK 220
PRK13808 PRK13808
adenylate kinase; Provisional
 31-238 1.80e-22

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 93.80  E-value: 1.80e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  31 IIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHlkiRG 110
Cdd:PRK13808    4 ILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAA---NG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 111 FVLDGWTRIIFEAiladEALEWYEWDKNVK---VILLNISRRESYNRLTKRrqckkcghlipwIGEFKKLkkcdkcgGEL 187
Cdd:PRK13808   81 FILDGFPRTVPQA----EALDALLKDKQLKldaVVELRVNEGALLARVETR------------VAEMRAR-------GEE 137

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1279228384 188 ItRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDI 238
Cdd:PRK13808  138 V-RADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDGMMTIDEVTREI 187
PLN02459 PLN02459
probable adenylate kinase
 29-242 1.98e-22

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 92.22  E-value: 1.98e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  29 VFIivGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFKKHLKi 108
Cdd:PLN02459   33 VFL--GCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAGEEEGE- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 109 RGFVLDGWTRIIFEAILADEALEwyewdknvKVILLNISRRESYnRLTK---RRQCKKCGH-----LIPWIGE------- 173
Cdd:PLN02459  110 SGFILDGFPRTVRQAEILEGVTD--------IDLVVNLKLREEV-LVEKclgRRICSECGKnfnvaDIDLKGEdgrpgiv 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279228384 174 FKKLKKCDKCGGELITRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDILKAI 242
Cdd:PLN02459  181 MPPLLPPPECASKLITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEFELPGGIPETWPRLLQAL 249
PLN02842 PLN02842
nucleotide kinase
 31-238 1.13e-20

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 90.31  E-value: 1.13e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  31 IIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLEnfKKHLKIRG 110
Cdd:PLN02842    1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLS--REDAKEKG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 111 FVLDGWTRIIFEAiladEALEWYEWDKNVkVILLNISRRESYNRLTKRRqckkcghLIPWIGEFKKLK----KCDKCGGE 186
Cdd:PLN02842   79 WLLDGYPRSFAQA----QSLEKLKIRPDI-FILLDVPDEILIDRCVGRR-------LDPVTGKIYHIKnfppESEEIKAR 146

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279228384 187 LITRADDKMESIKKRLEEYKNQTKKAINYYKKQgrLIEINGGQSIEDVFKDI 238
Cdd:PLN02842  147 LITRPDDTEEKVKARLQIYKKNAEAILSTYSDI--MVKIDGNRPKEVVFEEI 196
PLN02200 PLN02200
adenylate kinase family protein
 19-239 1.71e-18

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 81.09  E-value: 1.71e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  19 GRRVGVQNPKVFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDV 98
Cdd:PLN02200   35 GSSSKEKTPFITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKE 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  99 LENFKKhlkiRGFVLDGW-----TRIIFEAILADEAlewyewdkNVkVILLNISRRESYNRLTKRRQckkcghlipwige 173
Cdd:PLN02200  115 MESSDN----NKFLIDGFprteeNRIAFERIIGAEP--------NV-VLFFDCPEEEMVKRVLNRNQ------------- 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1279228384 174 fkklkkcdkcggeliTRADDKMESIKKRLEEYKNQTKKAINYYKKQGRLIEINGGQSIEDVFKDIL 239
Cdd:PLN02200  169 ---------------GRVDDNIDTIKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTVDEIFEQVR 219
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 24-220 3.12e-18

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 80.61  E-value: 3.12e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  24 VQNPKVFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGDFTGKKLIQAMGRGELAPSFVIVKILGDVLENFK 103
Cdd:PTZ00088    3 LKGPLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384 104 KHlKIRGFVLDGWTRIIFEAIladealEWYEWDKNVKVILLNISRRESYNRLTKRRQCKKCGH-------------LIPW 170
Cdd:PTZ00088   83 DD-CFKGFILDGFPRNLKQCK------ELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRnfniahirsdpydMPPI 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279228384 171 IGEfkklKKCDKCGG--ELITRADDKMESIKKRLEEYKNQTKKAINYYKKQG 220
Cdd:PTZ00088  156 LPP----ADCEGCKGnpKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNEN 203
AAA_17 pfam13207
AAA domain;
33-159 8.85e-14

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 66.11  E-value: 8.85e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279228384  33 VGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRARQKIGdfTGKKLIQAMGRGELAPSFVIVKILgdvLENFKKHLKIRGFV 112
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKER--GLVEDRDEMRKLPLEPQKELQKLA---AERIAEEAGEGGVI 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1279228384 113 LDGWTRIIFEAILADEALEWYEWDKNV-KVILLNISRRESYNRLTKRR 159
Cdd:pfam13207  76 VDGHPRIKTPAGYLPGLPVEVLRELKPdAIILLEADPEEILERRLKDR 123
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 158-192 3.80e-06

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 42.45  E-value: 3.80e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1279228384 158 RRQCKKCGH-----LIPWigefKKLKKCDKCGGELITRAD 192
Cdd:pfam05191   1 RRVCPKCGRiyhvyFNPP----KVEGVCDVCGGELVQRDD 36
PRK04182 PRK04182
cytidylate kinase; Provisional
 29-63 4.77e-06

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 45.57  E-value: 4.77e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1279228384  29 VFIIV-GPPGSGKGTQAKLLCQKFGLEYVGSGDTLR 63
Cdd:PRK04182    1 MIITIsGPPGSGKTTVARLLAEKLGLKHVSAGEIFR 36
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 29-63 1.64e-05

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 43.95  E-value: 1.64e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1279228384  29 VFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLR 63
Cdd:TIGR02173   2 IITISGPPGSGKTTVAKILAEKLSLKLISAGDIFR 36
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 32-60 3.15e-05

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 42.86  E-value: 3.15e-05
                          10        20
                  ....*....|....*....|....*....
gi 1279228384  32 IVGPPGSGKGTQAKLLCQKFGLEYVGSGD 60
Cdd:cd02020     4 IDGPAGSGKSTVAKLLAKKLGLPYLDTGG 32
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 29-65 6.52e-04

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 38.83  E-value: 6.52e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1279228384  29 VFIIVGPPGSGKGTQAKLLCQKFGLEYVGSgDTLRAR 65
Cdd:pfam13671   1 LILLVGLPGSGKSTLARRLLEELGAVRLSS-DDERKR 36
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 32-64 1.18e-03

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 38.82  E-value: 1.18e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1279228384  32 IVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLRA 64
Cdd:pfam02224   3 IDGPSGSGKSTVARILARKLGYKYLDTGAMYRA 35
Kti12 COG4088
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ...
 27-58 1.50e-03

tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];


Pssm-ID: 443264 [Multi-domain]  Cd Length: 179  Bit Score: 38.17  E-value: 1.50e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1279228384  27 PKVFIIVGPPGSGKGTQAKLLCQKFGLEYVGS 58
Cdd:COG4088     4 PMLLILTGPPGSGKTTFAKALAQRLYAEGIAV 35
pseT PHA02530
polynucleotide kinase; Provisional
 27-75 2.04e-03

polynucleotide kinase; Provisional


Pssm-ID: 222856 [Multi-domain]  Cd Length: 300  Bit Score: 38.46  E-value: 2.04e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1279228384  27 PKVFIIVGPPGSGKGTQAKLLCQKFGLEYVGSGDTLR----ARQKIGDFTGKK 75
Cdd:PHA02530    2 MKIILTVGVPGSGKSTWAREFAAKNPKAVNVNRDDLRqslfGHGEWGEYKFTK 54
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
29-65 2.82e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 37.20  E-value: 2.82e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1279228384  29 VFIIVGPPGSGKGTQAKLLCQKFGLEYVGSgDTLRAR 65
Cdd:COG0645     1 LILVCGLPGSGKSTLARALAERLGAVRLRS-DVVRKR 36
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
34-59 6.43e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 36.93  E-value: 6.43e-03
                          10        20
                  ....*....|....*....|....*.
gi 1279228384  34 GPPGSGKGTQAKLLCQKFGLEYVGSG 59
Cdd:COG0283     7 GPAGSGKSTVAKALAKRLGYHYLDTG 32
COG4639 COG4639
Predicted kinase [General function prediction only];
27-65 8.89e-03

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 35.58  E-value: 8.89e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1279228384  27 PKVFIIVGPPGSGKGTQAKLLCQkfGLEYVGSgDTLRAR 65
Cdd:COG4639     2 LSLVVLIGLPGSGKSTFARRLFA--PTEVVSS-DDIRAL 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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