|
Name |
Accession |
Description |
Interval |
E-value |
| COG3292 |
COG3292 |
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; |
20-944 |
4.54e-142 |
|
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
Pssm-ID: 442521 [Multi-domain] Cd Length: 924 Bit Score: 449.05 E-value: 4.54e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 20 LAVVARAQTSSALTFHTLTAAQGLSENSVYSIVQDRRGFLWFGTQDGLSRYDGVEFRVFRNDPQRSGSLSSNFILSLTED 99
Cdd:COG3292 10 LLLSLFAQAAQQYRFRHLTVEDGLPQNSVNSIAQDSDGFLWIGTEDGLNRYDGYEFKVFRHDPGDPNSLPSNYIRALLED 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 100 QQGQLWVGTgGGGLCRYNHVTGRFRSFEYEPtdenGLADNFVRVVYCDRQGRVWAGTEGGLHRFEPRKNHFQRFVHaasl 179
Cdd:COG3292 90 SDGRLWIGT-DGGLSRYDPKTDKFTRYPLDP----GLPNNSIRSIAEDSDGNIWVGTSNGLYRYDPKTGKFKRFTL---- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 180 pENLRRNSVRAITQSATGTLWVgtgegrisrlnpatgyleadprwaptsaitalqpDKQGGLWVGTETDGLWyvpatgpr 259
Cdd:COG3292 161 -DGLPSNTITSLAEDADGNLWV----------------------------------DSDGNLWIGTDGNGLY-------- 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 260 qgigqrvaagpgeairalfldqqqhvwigtnkglvRYQPVAHTFTTYQHQSGvVHSLPDNVVLSVFQDRSGLLWTGTEGG 339
Cdd:COG3292 198 -----------------------------------RLDPNTGKFEHITHDPD-PNSLSSNSIYSLFEDREGNLWVGTYGG 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 340 issfeaqpsafaaypglagrpngpvwavaedaagtvwvgteslGLVSYNPATGQRREFRHHpqDPGSLSEDFVRALCFDR 419
Cdd:COG3292 242 -------------------------------------------GLNYLDPNNSKFKSYRHN--DPNGLSGNSVRSIAEDS 276
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 420 QG----RLWVGTQSQGLDCLEPGATRFRHYRhdpavKNTISEDFIRTIYEGPDGRLWVGTE-GGLNRFEPDKDGFTSFRN 494
Cdd:COG3292 277 DGnlwiRLWIGTYGGGLFRLDPKTGKFKRYN-----PNGLPSNSVYSILEDSDGNLWIGTSgGGLYRYDPKTGKFTKFSE 351
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 495 DPanprSLSNNFVRVVHQDRTGRVWVGTgGGGLCCYNPVTGQFSAFRTdDRNPRSLSSNFVRSILEDHAGQLWVGTEGGG 574
Cdd:COG3292 352 DN----GLSNNFIRSILEDSDGNLWVGT-NGGLYRLDPKTGKFTNFTH-DPDKNGLSSNYINSIFEDSDGRLWIGTDGGG 425
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 575 LCRLdDARRGIFTTFREPQGLPNDVVYGVLEDAQQHLWlstnkglARFTPANNQFYTFDTRDGLPFDEFNAGGYYASPSG 654
Cdd:COG3292 426 LYRY-DPKTGKFKHFTTKDGLPSNTIYSILEDDNGNLW-------NFNSASNLGLLSLLGGLLGGLNLGNAIKLPLSNLG 497
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 655 RLYFGGVQGLVSFQPGAVRTNAVPPPVVLTGFrkfnqpveldtsitvrrRIVLGPQDYFFSVEFAALNFRLPEKNRYAYM 734
Cdd:COG3292 498 LLLTLLLLGINLSLVRSLISLLTLLLLALLLL-----------------LSLLLLLLLLLLLLLLLLLLLLLLLLLILLL 560
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 735 LENFDPDWVQAGTKREATYTNLDPGTYTFRVRATNNDGIWNPRGTALTIVVQPHWYGTWWFRILISWVLFGLLFLAYRLR 814
Cdd:COG3292 561 LLLRLLLLLLLLELLERLLALLLEIELLLTLLLLLLLLLLLLLLLLILLLLLLLLLLLLILLLLLLLLLLLLILLLLLLL 640
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 815 VRQLLALERVRHNIARDLHddmgstlssisilsQIARTHQHNQRTDQATALLDQIGDSSRRMLDAMDDIVWTINPAHDSM 894
Cdd:COG3292 641 LLLLLLLLLRLLLELLLLE--------------LELLLELLLLLAELILELLLILLLLLLLLLLALLLLLLLLLALKLLL 706
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|
gi 1280271109 895 DDVVARMRSFASDVLEARGIDFTFRADPSIAGLRLNMRARREFFLLFKEA 944
Cdd:COG3292 707 LLLLILLLLLLLLGLLLLLLDLVLLLLLLILLIILLLLILLEELLLANDI 756
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
943-1023 |
6.80e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 93.77 E-value: 6.80e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 943 EAVNNLAKYAQCTEAAITLAYEHQRLVLTVQDDGVGFDPQAPAQGGGNGLTNMNSRAAAMKGVLDIQTAPGQGTVLRLNV 1022
Cdd:cd16917 7 EALTNALKHAGASRVRVTLSYTADELTLTVVDDGVGFDGPAPPGGGGFGLLGMRERAELLGGTLTIGSRPGGGTRVTARL 86
|
.
gi 1280271109 1023 P 1023
Cdd:cd16917 87 P 87
|
|
| Y_Y_Y |
pfam07495 |
Y_Y_Y domain; This domain is mostly found at the end of the beta propellers (pfam07494) in a ... |
722-786 |
2.98e-22 |
|
Y_Y_Y domain; This domain is mostly found at the end of the beta propellers (pfam07494) in a family of two component regulators. However they are also found tandemly repeated in Swiss:Q891H4 without other signal conduction domains being present. It's named after the conserved tyrosines found in the alignment. The exact function is not known.
Pssm-ID: 400051 [Multi-domain] Cd Length: 65 Bit Score: 90.87 E-value: 2.98e-22
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1280271109 722 NFRLPEKNRYAYMLENFDPDWVQAGTKREATYTNLDPGTYTFRVRATNNDGIWNPRGTALTIVVQ 786
Cdd:pfam07495 1 NYDGPENLLYRYRLEGFDGEWVELGDYSEASYTNLPPGKYTLKVKAKDNDGNWSYDDASLNFTIL 65
|
|
| PRK11644 |
PRK11644 |
signal transduction histidine-protein kinase/phosphatase UhpB; |
816-1024 |
1.76e-16 |
|
signal transduction histidine-protein kinase/phosphatase UhpB;
Pssm-ID: 236945 [Multi-domain] Cd Length: 495 Bit Score: 83.49 E-value: 1.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 816 RQLL-ALERVRHNIARDLHDDMGSTLSSISILSQI-ARTHQHNQRTDQATALLDQIgdsSRRMLDAMDDIVWTINPAhdS 893
Cdd:PRK11644 292 ERLLeTEESVRRDVARELHDEIGQTITAIRTQAGIiKRLAADNASVKQSAQLIEQL---SLGVYDTVRRLLGRLRPR--Q 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 894 MDD------VVARMRSFAsdvLEARGID--FTFRADPSIaglrLNMRARREFFLLFKEAVNNLAKYAQCTEAAITLAYEH 965
Cdd:PRK11644 367 LDDltleqaIRSLMREME---LEDRGIVshLDWRIDESA----LSETQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQD 439
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1280271109 966 QRLVLTVQDDGVGFDPQAPAQggGNGLTNMNSRAAAMKGVLDIQTAPGQgtvlRLNVPL 1024
Cdd:PRK11644 440 ERLMLVIEDDGSGLPPGSGQQ--GFGLRGMRERVTALGGTLTISCTHGT----RLSVSL 492
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
934-1025 |
2.76e-10 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 58.53 E-value: 2.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 934 RREFFLLFKEAVNNLAKYA-QCTEAAITLAYEHqRLVLTVQDDGVGFDPQ--------------APAQGGGNGLTNMNSR 998
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHAaKAGEITVTLSEGG-ELTLTVEDNGIGIPPEdlprifepfstadkRGGGGTGLGLSIVRKL 81
|
90 100
....*....|....*....|....*..
gi 1280271109 999 AAAMKGVLDIQTAPGQGTVLRLNVPLK 1025
Cdd:pfam02518 82 VELLGGTITVESEPGGGTTVTLTLPLA 108
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
934-1025 |
6.67e-09 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 54.58 E-value: 6.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 934 RREFFLLFKEAVNNLAKYA-QCTEAAITLAYEHQRLVLTVQDDGVGFDPQA----------------PAQGGGNGLTNMN 996
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTpEGGRITVTLERDGDHVEITVEDNGPGIPPEDlekifepffrtdkrsrKIGGTGLGLSIVK 82
|
90 100
....*....|....*....|....*....
gi 1280271109 997 SRAAAMKGVLDIQTAPGQGTVLRLNVPLK 1025
Cdd:smart00387 83 KLVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| PRK10600 |
PRK10600 |
nitrate/nitrite two-component system sensor histidine kinase NarX; |
942-1016 |
3.42e-08 |
|
nitrate/nitrite two-component system sensor histidine kinase NarX;
Pssm-ID: 182581 [Multi-domain] Cd Length: 569 Bit Score: 57.37 E-value: 3.42e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1280271109 942 KEAVNNLAKYAQCTEAAITLAYEHQRLVLTVQDDGVGFdPQAPAQGGGNGLTNMNSRAAAMKGVLDIQTAPGQGT 1016
Cdd:PRK10600 475 REALSNALKHAQASEVVVTVAQNQNQVKLSVQDNGCGV-PENAERSNHYGLIIMRDRAQSLRGDCRVRRRESGGT 548
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
893-1026 |
4.70e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 53.76 E-value: 4.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 893 SMDDVVARMRSFASDVLEARGIDFTFRADPsiagLRLNMR-----ArreffLLFKEAVNNLAKYAQCTEAA----ITLAY 963
Cdd:COG3920 360 DLRDYLRELLEPLRDSYGGRGIRIELDGPD----VELPADaavplG-----LILNELVTNALKHAFLSGEGgrirVSWRR 430
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1280271109 964 EHQRLVLTVQDDGVGFDPQA-PAQGGGNGLTNMNSRAAAMKGVLDIQtaPGQGTVLRLNVPLKS 1026
Cdd:COG3920 431 EDGRLRLTVSDNGVGLPEDVdPPARKGLGLRLIRALVRQLGGTLELD--RPEGTRVRITFPLAE 492
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
737-785 |
2.45e-04 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 40.56 E-value: 2.45e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1280271109 737 NFDPDWVQAGTKREATYTNLDPGTYTFRVRATNNDGIWNPRGTalTIVV 785
Cdd:cd00146 35 DFGDGEVSSSGEPTVTHTYTKPGTYTVTLTVTNAVGSSSTKTT--TVVV 81
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG3292 |
COG3292 |
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; |
20-944 |
4.54e-142 |
|
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
Pssm-ID: 442521 [Multi-domain] Cd Length: 924 Bit Score: 449.05 E-value: 4.54e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 20 LAVVARAQTSSALTFHTLTAAQGLSENSVYSIVQDRRGFLWFGTQDGLSRYDGVEFRVFRNDPQRSGSLSSNFILSLTED 99
Cdd:COG3292 10 LLLSLFAQAAQQYRFRHLTVEDGLPQNSVNSIAQDSDGFLWIGTEDGLNRYDGYEFKVFRHDPGDPNSLPSNYIRALLED 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 100 QQGQLWVGTgGGGLCRYNHVTGRFRSFEYEPtdenGLADNFVRVVYCDRQGRVWAGTEGGLHRFEPRKNHFQRFVHaasl 179
Cdd:COG3292 90 SDGRLWIGT-DGGLSRYDPKTDKFTRYPLDP----GLPNNSIRSIAEDSDGNIWVGTSNGLYRYDPKTGKFKRFTL---- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 180 pENLRRNSVRAITQSATGTLWVgtgegrisrlnpatgyleadprwaptsaitalqpDKQGGLWVGTETDGLWyvpatgpr 259
Cdd:COG3292 161 -DGLPSNTITSLAEDADGNLWV----------------------------------DSDGNLWIGTDGNGLY-------- 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 260 qgigqrvaagpgeairalfldqqqhvwigtnkglvRYQPVAHTFTTYQHQSGvVHSLPDNVVLSVFQDRSGLLWTGTEGG 339
Cdd:COG3292 198 -----------------------------------RLDPNTGKFEHITHDPD-PNSLSSNSIYSLFEDREGNLWVGTYGG 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 340 issfeaqpsafaaypglagrpngpvwavaedaagtvwvgteslGLVSYNPATGQRREFRHHpqDPGSLSEDFVRALCFDR 419
Cdd:COG3292 242 -------------------------------------------GLNYLDPNNSKFKSYRHN--DPNGLSGNSVRSIAEDS 276
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 420 QG----RLWVGTQSQGLDCLEPGATRFRHYRhdpavKNTISEDFIRTIYEGPDGRLWVGTE-GGLNRFEPDKDGFTSFRN 494
Cdd:COG3292 277 DGnlwiRLWIGTYGGGLFRLDPKTGKFKRYN-----PNGLPSNSVYSILEDSDGNLWIGTSgGGLYRYDPKTGKFTKFSE 351
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 495 DPanprSLSNNFVRVVHQDRTGRVWVGTgGGGLCCYNPVTGQFSAFRTdDRNPRSLSSNFVRSILEDHAGQLWVGTEGGG 574
Cdd:COG3292 352 DN----GLSNNFIRSILEDSDGNLWVGT-NGGLYRLDPKTGKFTNFTH-DPDKNGLSSNYINSIFEDSDGRLWIGTDGGG 425
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 575 LCRLdDARRGIFTTFREPQGLPNDVVYGVLEDAQQHLWlstnkglARFTPANNQFYTFDTRDGLPFDEFNAGGYYASPSG 654
Cdd:COG3292 426 LYRY-DPKTGKFKHFTTKDGLPSNTIYSILEDDNGNLW-------NFNSASNLGLLSLLGGLLGGLNLGNAIKLPLSNLG 497
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 655 RLYFGGVQGLVSFQPGAVRTNAVPPPVVLTGFrkfnqpveldtsitvrrRIVLGPQDYFFSVEFAALNFRLPEKNRYAYM 734
Cdd:COG3292 498 LLLTLLLLGINLSLVRSLISLLTLLLLALLLL-----------------LSLLLLLLLLLLLLLLLLLLLLLLLLLILLL 560
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 735 LENFDPDWVQAGTKREATYTNLDPGTYTFRVRATNNDGIWNPRGTALTIVVQPHWYGTWWFRILISWVLFGLLFLAYRLR 814
Cdd:COG3292 561 LLLRLLLLLLLLELLERLLALLLEIELLLTLLLLLLLLLLLLLLLLILLLLLLLLLLLLILLLLLLLLLLLLILLLLLLL 640
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 815 VRQLLALERVRHNIARDLHddmgstlssisilsQIARTHQHNQRTDQATALLDQIGDSSRRMLDAMDDIVWTINPAHDSM 894
Cdd:COG3292 641 LLLLLLLLLRLLLELLLLE--------------LELLLELLLLLAELILELLLILLLLLLLLLLALLLLLLLLLALKLLL 706
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|
gi 1280271109 895 DDVVARMRSFASDVLEARGIDFTFRADPSIAGLRLNMRARREFFLLFKEA 944
Cdd:COG3292 707 LLLLILLLLLLLLGLLLLLLDLVLLLLLLILLIILLLLILLEELLLANDI 756
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
798-1026 |
1.97e-46 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 167.10 E-value: 1.97e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 798 LISWVLFGLLFLAYRLRVRQ---------------LLALERVRHNIARDLHDDMGSTLSSISILSQIARtHQHNQRTDQA 862
Cdd:COG4585 12 LLVGALLGLLLALVLLRARRaeraaelerelaaraEEAREEERRRIARELHDGVGQSLSAIKLQLEAAR-RLLDADPEAA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 863 TALLDQIGDSSRRMLDAMDDIVWTINPAHDSMDDVVARMRSFASDVLEARGIDFTFRADPSIAglRLNMRARREFFLLFK 942
Cdd:COG4585 91 REELEEIRELAREALAELRRLVRGLRPPALDDLGLAAALEELAERLLRAAGIRVELDVDGDPD--RLPPEVELALYRIVQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 943 EAVNNLAKYAQCTEAAITLAYEHQRLVLTVQDDGVGFDPQAPAqGGGNGLTNMNSRAAAMKGVLDIQTAPGQGTVLRLNV 1022
Cdd:COG4585 169 EALTNALKHAGATRVTVTLEVDDGELTLTVRDDGVGFDPEAAP-GGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATL 247
|
....
gi 1280271109 1023 PLKS 1026
Cdd:COG4585 248 PLAA 251
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
943-1023 |
6.80e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 93.77 E-value: 6.80e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 943 EAVNNLAKYAQCTEAAITLAYEHQRLVLTVQDDGVGFDPQAPAQGGGNGLTNMNSRAAAMKGVLDIQTAPGQGTVLRLNV 1022
Cdd:cd16917 7 EALTNALKHAGASRVRVTLSYTADELTLTVVDDGVGFDGPAPPGGGGFGLLGMRERAELLGGTLTIGSRPGGGTRVTARL 86
|
.
gi 1280271109 1023 P 1023
Cdd:cd16917 87 P 87
|
|
| Y_Y_Y |
pfam07495 |
Y_Y_Y domain; This domain is mostly found at the end of the beta propellers (pfam07494) in a ... |
722-786 |
2.98e-22 |
|
Y_Y_Y domain; This domain is mostly found at the end of the beta propellers (pfam07494) in a family of two component regulators. However they are also found tandemly repeated in Swiss:Q891H4 without other signal conduction domains being present. It's named after the conserved tyrosines found in the alignment. The exact function is not known.
Pssm-ID: 400051 [Multi-domain] Cd Length: 65 Bit Score: 90.87 E-value: 2.98e-22
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1280271109 722 NFRLPEKNRYAYMLENFDPDWVQAGTKREATYTNLDPGTYTFRVRATNNDGIWNPRGTALTIVVQ 786
Cdd:pfam07495 1 NYDGPENLLYRYRLEGFDGEWVELGDYSEASYTNLPPGKYTLKVKAKDNDGNWSYDDASLNFTIL 65
|
|
| UhpB |
COG3851 |
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction ... |
809-1026 |
4.87e-20 |
|
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction mechanisms];
Pssm-ID: 443060 [Multi-domain] Cd Length: 493 Bit Score: 94.69 E-value: 4.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 809 LAYRLRVRQLLA------LERVRHNIARDLHDDMGSTLSSISILSQIAR----THQHNQRTDQATALLDQIGDSSRRMLD 878
Cdd:COG3851 271 LEQELRENRALArqlvsaEESERREIARELHDEIGQNITAIRTQASILKrlapQPEIEQSAQSIESLALRIYDTTRRLLD 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 879 -----AMDDIvwtinPAHDSMDDVVARMRsfasdvLEARGIDFTFRADpsIAGLRLNMRARREFFLLFKEAVNNLAKYAQ 953
Cdd:COG3851 351 rlrpaVLDEL-----GLEEALRELPRELA------FEEPGISCQLDLR--GDPSLLDDTLQLTLYRLVQEALTNILKHAE 417
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1280271109 954 CTEAAITLAYEHQRLVLTVQDDGVGFDPQAPAqgGGNGLTNMNSRAAAMKGVLDIQTAPgQGTVLRLNVPLKS 1026
Cdd:COG3851 418 ASQIRISLSQDKRLLSLEIRDDGIGLPPELRA--KGFGLRGMRERVRALGGDFRLSSAP-KGTRLSVLLPTPA 487
|
|
| PRK11644 |
PRK11644 |
signal transduction histidine-protein kinase/phosphatase UhpB; |
816-1024 |
1.76e-16 |
|
signal transduction histidine-protein kinase/phosphatase UhpB;
Pssm-ID: 236945 [Multi-domain] Cd Length: 495 Bit Score: 83.49 E-value: 1.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 816 RQLL-ALERVRHNIARDLHDDMGSTLSSISILSQI-ARTHQHNQRTDQATALLDQIgdsSRRMLDAMDDIVWTINPAhdS 893
Cdd:PRK11644 292 ERLLeTEESVRRDVARELHDEIGQTITAIRTQAGIiKRLAADNASVKQSAQLIEQL---SLGVYDTVRRLLGRLRPR--Q 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 894 MDD------VVARMRSFAsdvLEARGID--FTFRADPSIaglrLNMRARREFFLLFKEAVNNLAKYAQCTEAAITLAYEH 965
Cdd:PRK11644 367 LDDltleqaIRSLMREME---LEDRGIVshLDWRIDESA----LSETQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQD 439
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1280271109 966 QRLVLTVQDDGVGFDPQAPAQggGNGLTNMNSRAAAMKGVLDIQTAPGQgtvlRLNVPL 1024
Cdd:PRK11644 440 ERLMLVIEDDGSGLPPGSGQQ--GFGLRGMRERVTALGGTLTISCTHGT----RLSVSL 492
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
46-244 |
8.38e-14 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 72.74 E-value: 8.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 46 NSVYSIVQDRRGFLWFGT--QDGLSRYDGV--EFRVFrndpqrSGSLSSNFILSLTEDQQGQLWV-GTGGGGLCRYNHVT 120
Cdd:COG4257 59 SGPHGIAVDPDGNLWFTDngNNRIGRIDPKtgEITTF------ALPGGGSNPHGIAFDPDGNLWFtDQGGNRIGRLDPAT 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 121 GRFRSFEYePTDENGLADnfvrvVYCDRQGRVWAGTEGG--LHRFEPRKNHFQRFvhaaSLPENLRRnsVRAITQSATGT 198
Cdd:COG4257 133 GEVTEFPL-PTGGAGPYG-----IAVDPDGNLWVTDFGAnaIGRIDPDTGTLTEY----ALPTPGAG--PRGLAVDPDGN 200
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1280271109 199 LWVG-TGEGRISRLNPATGYLEADPRWAPTSAITALQPDKQGGLWVG 244
Cdd:COG4257 201 LWVAdTGSGRIGRFDPKTGTVTEYPLPGGGARPYGVAVDGDGRVWFA 247
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
189-429 |
9.20e-14 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 72.74 E-value: 9.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 189 RAITQSATGTLWV-GTGEGRISRLNPATGYLeADPRWAPTSAITALQPDKQGGLWVGTETDG-LWYV-PATGPRQGIgqr 265
Cdd:COG4257 20 RDVAVDPDGAVWFtDQGGGRIGRLDPATGEF-TEYPLGGGSGPHGIAVDPDGNLWFTDNGNNrIGRIdPKTGEITTF--- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 266 vaAGPGEAIR--ALFLDQQQHVWI--GTNKGLVRYQPVAHTFTTYqhQSGVVHSLPDNVVLsvfqDRSGLLWTGTEGG-- 339
Cdd:COG4257 96 --ALPGGGSNphGIAFDPDGNLWFtdQGGNRIGRLDPATGEVTEF--PLPTGGAGPYGIAV----DPDGNLWVTDFGAna 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 340 ISSFEAQPSAFAAY--PGLAGRPNGpvwaVAEDAAGTVWVG-TESLGLVSYNPATGQRREFrhhpqdPGSLSEDFVRALC 416
Cdd:COG4257 168 IGRIDPDTGTLTEYalPTPGAGPRG----LAVDPDGNLWVAdTGSGRIGRFDPKTGTVTEY------PLPGGGARPYGVA 237
|
250
....*....|...
gi 1280271109 417 FDRQGRLWVGTQS 429
Cdd:COG4257 238 VDGDGRVWFAESG 250
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
317-574 |
1.78e-13 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 71.97 E-value: 1.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 317 PDNVVLSVFQDRSGLLW-TGTEGG-ISSFEAQPSAFAAYPglAGRPNGPvWAVAEDAAGTVWVGTESLG-LVSYNPATGQ 393
Cdd:COG4257 15 PGSGPRDVAVDPDGAVWfTDQGGGrIGRLDPATGEFTEYP--LGGGSGP-HGIAVDPDGNLWFTDNGNNrIGRIDPKTGE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 394 RREFrhhpqdPGSLSEDFVRALCFDRQGRLWVGTQSQGldclepgatrfRHYRHDPAvKNTISEDFIRT-------IYEG 466
Cdd:COG4257 92 ITTF------ALPGGGSNPHGIAFDPDGNLWFTDQGGN-----------RIGRLDPA-TGEVTEFPLPTggagpygIAVD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 467 PDGRLWVGTEGG--LNRFEPDKDGFTSFR--NDPANPRSLSnnfvrvvhQDRTGRVWVG-TGGGGLCCYNPVTGQFSAFR 541
Cdd:COG4257 154 PDGNLWVTDFGAnaIGRIDPDTGTLTEYAlpTPGAGPRGLA--------VDPDGNLWVAdTGSGRIGRFDPKTGTVTEYP 225
|
250 260 270
....*....|....*....|....*....|...
gi 1280271109 542 TDDRNPRslssnfVRSILEDHAGQLWVGTEGGG 574
Cdd:COG4257 226 LPGGGAR------PYGVAVDGDGRVWFAESGAN 252
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
269-535 |
1.45e-11 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 66.20 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 269 GPGEAIRALFLDQQQHVWI-GTNKG-LVRYQPVAHTFTTYQHQSGvvhSLPDNVVLsvfqDRSGLLW------------T 334
Cdd:COG4257 14 APGSGPRDVAVDPDGAVWFtDQGGGrIGRLDPATGEFTEYPLGGG---SGPHGIAV----DPDGNLWftdngnnrigriD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 335 GTEGGISSFeaqpsafaAYPGLAGRPNGpvwaVAEDAAGTVWVgTESLG--LVSYNPATGQRREFrhhpqdPGSLSEDFV 412
Cdd:COG4257 87 PKTGEITTF--------ALPGGGSNPHG----IAFDPDGNLWF-TDQGGnrIGRLDPATGEVTEF------PLPTGGAGP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 413 RALCFDRQGRLWVG-TQSQGLDCLEPGATRFRHYrhdpAVKNTISEdfIRTIYEGPDGRLWVG--TEGGLNRFEPDKDGF 489
Cdd:COG4257 148 YGIAVDPDGNLWVTdFGANAIGRIDPDTGTLTEY----ALPTPGAG--PRGLAVDPDGNLWVAdtGSGRIGRFDPKTGTV 221
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1280271109 490 TSFRNDPANPRSLSnnfvrvVHQDRTGRVWVGTGGGG-LCCYNPVTG 535
Cdd:COG4257 222 TEYPLPGGGARPYG------VAVDGDGRVWFAESGANrIVRFDPDTE 262
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
934-1025 |
2.76e-10 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 58.53 E-value: 2.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 934 RREFFLLFKEAVNNLAKYA-QCTEAAITLAYEHqRLVLTVQDDGVGFDPQ--------------APAQGGGNGLTNMNSR 998
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHAaKAGEITVTLSEGG-ELTLTVEDNGIGIPPEdlprifepfstadkRGGGGTGLGLSIVRKL 81
|
90 100
....*....|....*....|....*..
gi 1280271109 999 AAAMKGVLDIQTAPGQGTVLRLNVPLK 1025
Cdd:pfam02518 82 VELLGGTITVESEPGGGTTVTLTLPLA 108
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
856-1024 |
9.57e-10 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 61.46 E-value: 9.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 856 NQRTDQATALLDQIGDSSRRMLDAMDDI---------VWTINPAHDSMDDVVARMRSFASDVLEARGIDFTFRADPSIAG 926
Cdd:COG0642 137 EELDEEQREYLETILRSADRLLRLINDLldlsrleagKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPT 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 927 LRLNMRarrefflLFKEAVNNL----AKYA-QCTEAAITLAYEHQRLVLTVQDDGVG---------FDP----QAPAQGG 988
Cdd:COG0642 217 VRGDPD-------RLRQVLLNLlsnaIKYTpEGGTVTVSVRREGDRVRISVEDTGPGippedleriFEPffrtDPSRRGG 289
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1280271109 989 GNGL-----TNMnsrAAAMKGVLDIQTAPGQGTVLRLNVPL 1024
Cdd:COG0642 290 GTGLglaivKRI---VELHGGTIEVESEPGKGTTFTVTLPL 327
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
934-1025 |
6.67e-09 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 54.58 E-value: 6.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 934 RREFFLLFKEAVNNLAKYA-QCTEAAITLAYEHQRLVLTVQDDGVGFDPQA----------------PAQGGGNGLTNMN 996
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTpEGGRITVTLERDGDHVEITVEDNGPGIPPEDlekifepffrtdkrsrKIGGTGLGLSIVK 82
|
90 100
....*....|....*....|....*....
gi 1280271109 997 SRAAAMKGVLDIQTAPGQGTVLRLNVPLK 1025
Cdd:smart00387 83 KLVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
49-221 |
2.35e-08 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 56.57 E-value: 2.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 49 YSIVQDRRGFLWF--GTQDGLSRYDGV--EFRVFRNdPQRSGSLSSnfilsLTEDQQGQLWVGT-GGGGLCRYNHVTGRF 123
Cdd:COG4257 105 HGIAFDPDGNLWFtdQGGNRIGRLDPAtgEVTEFPL-PTGGAGPYG-----IAVDPDGNLWVTDfGANAIGRIDPDTGTL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 124 RSFEYePTDENGladnFVRVVYcDRQGRVWAG--TEGGLHRFEPRKNHFQRFVH--AASLPEnlrrnsvrAITQSATGTL 199
Cdd:COG4257 179 TEYAL-PTPGAG----PRGLAV-DPDGNLWVAdtGSGRIGRFDPKTGTVTEYPLpgGGARPY--------GVAVDGDGRV 244
|
170 180
....*....|....*....|...
gi 1280271109 200 WVG-TGEGRISRLNPATGYLEAD 221
Cdd:COG4257 245 WFAeSGANRIVRFDPDTELTEYV 267
|
|
| PRK10600 |
PRK10600 |
nitrate/nitrite two-component system sensor histidine kinase NarX; |
942-1016 |
3.42e-08 |
|
nitrate/nitrite two-component system sensor histidine kinase NarX;
Pssm-ID: 182581 [Multi-domain] Cd Length: 569 Bit Score: 57.37 E-value: 3.42e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1280271109 942 KEAVNNLAKYAQCTEAAITLAYEHQRLVLTVQDDGVGFdPQAPAQGGGNGLTNMNSRAAAMKGVLDIQTAPGQGT 1016
Cdd:PRK10600 475 REALSNALKHAQASEVVVTVAQNQNQVKLSVQDNGCGV-PENAERSNHYGLIIMRDRAQSLRGDCRVRRRESGGT 548
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
331-532 |
4.04e-08 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 55.67 E-value: 4.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 331 LLWTGTEGG-ISSFEAQPSAFAAYPGLAGRPNGpvwaVAEDAAGTVWVGTESLGLVSYNPATGQRREFRHHPQDPGSLSE 409
Cdd:COG3386 21 LYWVDIPGGrIHRYDPDGGAVEVFAEPSGRPNG----LAFDPDGRLLVADHGRGLVRFDPADGEVTVLADEYGKPLNRPN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 410 DfvraLCFDRQGRLWVGTQSQgldclEPGATRFrhYRHDPAVKntisedfIRTIYEG----------PDGR-LWVG--TE 476
Cdd:COG3386 97 D----GVVDPDGRLYFTDMGE-----YLPTGAL--YRVDPDGS-------LRVLADGltfpngiafsPDGRtLYVAdtGA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1280271109 477 GGLNRFEPDKDG-------FTSFRNDPANPRSLsnnfvRVvhqDRTGRVWVGT-GGGGLCCYNP 532
Cdd:COG3386 159 GRIYRFDLDADGtlgnrrvFADLPDGPGGPDGL-----AV---DADGNLWVALwGGGGVVRFDP 214
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
859-1026 |
5.09e-08 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 54.91 E-value: 5.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 859 TDQATALLDQIGDSSRRMLDAMDDI---------VWTINPAHDSMDDVVARMRSFASDVLEARGIDFTFRADPSiaGLRL 929
Cdd:COG2205 49 PEERRELLEIIRESAERLLRLIEDLldlsrlesgKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPE--LPLV 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 930 NMRARReffllFKEAVNNL----AKYA-QCTEAAITLAYEHQRLVLTVQDDGVG---------FDP----QAPAQGGGNG 991
Cdd:COG2205 127 YADPEL-----LEQVLANLldnaIKYSpPGGTITISARREGDGVRISVSDNGPGipeeeleriFERfyrgDNSRGEGGTG 201
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1280271109 992 L-----TNMnsrAAAMKGVLDIQTAPGQGTVLRLNVPLKS 1026
Cdd:COG2205 202 LglaivKRI---VEAHGGTIWVESEPGGGTTFTVTLPLAE 238
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
54-165 |
1.02e-07 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 54.51 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 54 DRRGFLWFG--TQDGLSRYD--GVEFRVFRNDPQRSGSLssnfilslTEDQQGQLWVGTGGGGLCRYNHVTGRFRSFeye 129
Cdd:COG3386 16 DPDGRLYWVdiPGGRIHRYDpdGGAVEVFAEPSGRPNGL--------AFDPDGRLLVADHGRGLVRFDPADGEVTVL--- 84
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1280271109 130 pTDENGLADNFVRVVYCDRQGRVWAGT------EGGLHRFEP 165
Cdd:COG3386 85 -ADEYGKPLNRPNDGVVDPDGRLYFTDmgeylpTGALYRVDP 125
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
893-1026 |
4.70e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 53.76 E-value: 4.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 893 SMDDVVARMRSFASDVLEARGIDFTFRADPsiagLRLNMR-----ArreffLLFKEAVNNLAKYAQCTEAA----ITLAY 963
Cdd:COG3920 360 DLRDYLRELLEPLRDSYGGRGIRIELDGPD----VELPADaavplG-----LILNELVTNALKHAFLSGEGgrirVSWRR 430
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1280271109 964 EHQRLVLTVQDDGVGFDPQA-PAQGGGNGLTNMNSRAAAMKGVLDIQtaPGQGTVLRLNVPLKS 1026
Cdd:COG3920 431 EDGRLRLTVSDNGVGLPEDVdPPARKGLGLRLIRALVRQLGGTLELD--RPEGTRVRITFPLAE 492
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
898-1020 |
1.30e-06 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 48.37 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 898 VARMRSFASDVLEARGIDFTFRADpsIAglrlnmrarreffLLFKEAVNNLAKYAQCTEAA----ITLAYEHQRLVLTVQ 973
Cdd:COG2172 11 LGLARRAVRALLRELGLDEDDADD--LV-------------LAVSEAVTNAVRHAYGGDPDgpveVELELDPDGLEIEVR 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1280271109 974 DDGVGFDPQAPAQG------GGNGLTNMNSRAAAMkgvlDIQTAPGqGTVLRL 1020
Cdd:COG2172 76 DEGPGFDPEDLPDPystlaeGGRGLFLIRRLMDEV----EYESDPG-GTTVRL 123
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
947-1024 |
1.46e-06 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 52.34 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 947 NLAKYAQCTEAAITLAYEHQRLVLTVQDDGVGFDPQ------AP-------AQGGGNGLTNMNSRAAAMKGVLDIQTAPG 1013
Cdd:PRK15347 524 NAVKFTETGGIRLRVKRHEQQLCFTVEDTGCGIDIQqqqqifTPfyqadthSQGTGLGLTIASSLAKMMGGELTLFSTPG 603
|
90
....*....|.
gi 1280271109 1014 QGTVLRLNVPL 1024
Cdd:PRK15347 604 VGSCFSLVLPL 614
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
465-579 |
3.18e-06 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 49.89 E-value: 3.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 465 EGP----DGRLWVG--TEGGLNRFEPDKDGFTSFRNDPANPrslsnNFVRVvhqDRTGRVWVGTGGGGLCCYNPVTGQFS 538
Cdd:COG3386 11 EGPvwdpDGRLYWVdiPGGRIHRYDPDGGAVEVFAEPSGRP-----NGLAF---DPDGRLLVADHGRGLVRFDPADGEVT 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1280271109 539 AFrTDDRNPRSLSSNFVRSileDHAGQLWVGT-----EGGGLCRLD 579
Cdd:COG3386 83 VL-ADEYGKPLNRPNDGVV---DPDGRLYFTDmgeylPTGALYRVD 124
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
940-1023 |
5.73e-06 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 50.24 E-value: 5.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 940 LFKEAVNNLAKYAQCTEaaITLAYEHQ---RLVLTVQDDGVGFDPQAPAQGGgNGLTNMNSRAAAMKGVLDIQTAPGQGT 1016
Cdd:PRK10935 475 IIREATLNAIKHANASE--IAVSCVTNpdgEHTVSIRDDGIGIGELKEPEGH-YGLNIMQERAERLGGTLTISQPPGGGT 551
|
....*..
gi 1280271109 1017 VLRLNVP 1023
Cdd:PRK10935 552 TVSLTFP 558
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
819-1024 |
1.80e-05 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 48.42 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 819 LALERVRHNIARDLHDDMgstlssisilsqiarthqhnQRTDQATA-LLDQIgDSSRRMLDAMDDIVWTINPAHDSMD-- 895
Cdd:COG5000 221 LSAERLRRKLADKLEEDR--------------------EDLERALDtIIRQV-DRLKRIVDEFLDFARLPEPQLEPVDln 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 896 DVVARMRSFASDVLEARGIDFTFRADPSIAGLRLNMRarrefflLFKEAVNNLAKYAQctEAA-------ITLAYEHQRL 968
Cdd:COG5000 280 ELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRD-------QLEQVLINLLKNAI--EAIeeggeieVSTRREDGRV 350
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1280271109 969 VLTVQDDGVGFDPQA------P-----AQGGGNGLTNMNSRAAAMKGVLDIQTAPGQGTVLRLNVPL 1024
Cdd:COG5000 351 RIEVSDNGPGIPEEVlerifePffttkPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPL 417
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
561-659 |
2.23e-05 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 47.19 E-value: 2.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 561 DHAGQL-WVGTEGGGLCRLDDARRGIfTTFREPQGLPNdvvyGVLEDAQQHLWL-STNKGLARFTPANNQFYTFDTRDGL 638
Cdd:COG3386 16 DPDGRLyWVDIPGGRIHRYDPDGGAV-EVFAEPSGRPN----GLAFDPDGRLLVaDHGRGLVRFDPADGEVTVLADEYGK 90
|
90 100
....*....|....*....|.
gi 1280271109 639 PFDEFNAGGyyASPSGRLYFG 659
Cdd:COG3386 91 PLNRPNDGV--VDPDGRLYFT 109
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
959-1025 |
2.73e-05 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 47.71 E-value: 2.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 959 ITLAYEHQRLVLTVQDDGVGFDPQA----------PAQGGGNGLTNMNSRAAAM---KGVLDIQTAPGQGTVLRLNVPLK 1025
Cdd:COG2972 364 ISIRKEGDRLVITVEDNGVGMPEEKleklleelssKGEGRGIGLRNVRERLKLYygeEYGLEIESEPGEGTTVTIRIPLE 443
|
|
| HATPase_YehU-like |
cd16956 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
958-1023 |
5.75e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.
Pssm-ID: 340432 [Multi-domain] Cd Length: 101 Bit Score: 43.19 E-value: 5.75e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1280271109 958 AITLAYEHQRLVLTVQDDGVGFDPQAPAQGG-----GNGLTNMNSRAAAMKGV---LDIQTAPGQGTVLRLNVP 1023
Cdd:cd16956 28 EITARLDGQHLLLEVEDNGGGMDPDTLARILirssnGLGLNLVDKRLRQAFGNdygLDIECAPGEGTRITIRLP 101
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
737-785 |
2.45e-04 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 40.56 E-value: 2.45e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1280271109 737 NFDPDWVQAGTKREATYTNLDPGTYTFRVRATNNDGIWNPRGTalTIVV 785
Cdd:cd00146 35 DFGDGEVSSSGEPTVTHTYTKPGTYTVTLTVTNAVGSSSTKTT--TVVV 81
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
553-680 |
2.92e-04 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 43.85 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 553 NFVRSILEDHAGQLWV-GTEGGGLCRLDdARRGIFTTFREPQGlpnDVVYGVLEDAQQHLWLSTNKG--LARFTPANNQF 629
Cdd:COG4257 17 SGPRDVAVDPDGAVWFtDQGGGRIGRLD-PATGEFTEYPLGGG---SGPHGIAVDPDGNLWFTDNGNnrIGRIDPKTGEI 92
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1280271109 630 YTFDtrdgLPFDEFNAGGYYASPSGRLYFGGVQG--LVSFQP--GAVRTNAVPPP 680
Cdd:COG4257 93 TTFA----LPGGGSNPHGIAFDPDGNLWFTDQGGnrIGRLDPatGEVTEFPLPTG 143
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
859-1026 |
3.16e-04 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 44.07 E-value: 3.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 859 TDQATALLDQIGDSSRRMLDAMDDIvwtinpahdSMDDVVARMRSFASDVLeARGIDFTFRADPSIAGLRLNmrarREff 938
Cdd:COG3852 180 ADRLNNLVDRLLSFSRPRPPEREPV---------NLHEVLERVLELLRAEA-PKNIRIVRDYDPSLPEVLGD----PD-- 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 939 lLFKEAVNNLAKYAQctEAA-------ITLAYEHQR----------LVLTVQDDGVG---------FDP--QAPAQGGGN 990
Cdd:COG3852 244 -QLIQVLLNLVRNAA--EAMpeggtitIRTRVERQVtlgglrprlyVRIEVIDNGPGipeeildriFEPffTTKEKGTGL 320
|
170 180 190
....*....|....*....|....*....|....*.
gi 1280271109 991 GLTNMNSRAAAMKGVLDIQTAPGQGTVLRLNVPLKS 1026
Cdd:COG3852 321 GLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLEQ 356
|
|
| Reg_prop |
pfam07494 |
Two component regulator propeller; A large group of two component regulator proteins appear to ... |
549-572 |
4.67e-04 |
|
Two component regulator propeller; A large group of two component regulator proteins appear to have the same N-terminal structure of 14 tandem repeats. These repeats show homology to pfam01011 and pfam00400 indicating that they are likely to form a beta-propeller. This family has been built with artificially high cut-offs in order to avoid overlaps with other beta-propeller families. The fourteen repeats are likely to form two propellers; it is not clear if these structures are likely to recruit other proteins or interact with DNA.
Pssm-ID: 400050 [Multi-domain] Cd Length: 24 Bit Score: 38.45 E-value: 4.67e-04
|
| Reg_prop |
pfam07494 |
Two component regulator propeller; A large group of two component regulator proteins appear to ... |
42-65 |
8.57e-04 |
|
Two component regulator propeller; A large group of two component regulator proteins appear to have the same N-terminal structure of 14 tandem repeats. These repeats show homology to pfam01011 and pfam00400 indicating that they are likely to form a beta-propeller. This family has been built with artificially high cut-offs in order to avoid overlaps with other beta-propeller families. The fourteen repeats are likely to form two propellers; it is not clear if these structures are likely to recruit other proteins or interact with DNA.
Pssm-ID: 400050 [Multi-domain] Cd Length: 24 Bit Score: 37.68 E-value: 8.57e-04
|
| HATPase_c_2 |
pfam13581 |
Histidine kinase-like ATPase domain; |
898-994 |
1.13e-03 |
|
Histidine kinase-like ATPase domain;
Pssm-ID: 433327 [Multi-domain] Cd Length: 127 Bit Score: 39.96 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 898 VARMRSFASDVLEARGIDFTFRADPSIAglrlnmrarreffllFKEAVNNLAKYAQCTEAA----ITLAYEHQRLVLTVQ 973
Cdd:pfam13581 8 LRAARRVLEAVLRRAGLPEELLDEVELA---------------VGEACTNAVEHAYREGPEgpveVRLTSDGGGLVVTVA 72
|
90 100
....*....|....*....|.
gi 1280271109 974 DDGVGFDPQAPAQGGGNGLTN 994
Cdd:pfam13581 73 DSGPPFDPLTLPPPDLEEPDE 93
|
|
| HisKA_3 |
pfam07730 |
Histidine kinase; This is the dimerization and phosphoacceptor domain of a sub-family of ... |
822-890 |
1.55e-03 |
|
Histidine kinase; This is the dimerization and phosphoacceptor domain of a sub-family of histidine kinases. It shares sequence similarity with pfam00512 and pfam07536.
Pssm-ID: 429624 [Multi-domain] Cd Length: 68 Bit Score: 37.99 E-value: 1.55e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1280271109 822 ERVRhnIARDLHDDMGSTLSSISILSQIARtHQHNQRTDQATALLDQIGDSSRRMLDAMDDIVWTINPA 890
Cdd:pfam07730 1 ERNR--IARELHDSVGQSLTAIKLQLELAR-RLLDRDPEEAREQLDAIRELAREALQELRRLLGDLRPP 66
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
860-982 |
1.56e-03 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 42.46 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 860 DQATALLDQIGDSSRRMlDAM-DDIV-------WTINPAHDSMDDVVARMRSFASDVLEARGIDFTFRADPSIAGLRLNM 931
Cdd:COG4251 317 EEGREYLERIRDAAERM-QALiDDLLaysrvgrQELEFEPVDLNELLEEVLEDLEPRIEERGAEIEVGPLPTVRGDPTLL 395
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1280271109 932 RarreffLLFKEAVNNLAKYAQCTEAA-ITLAYEHQ--RLVLTVQDDGVGFDPQ 982
Cdd:COG4251 396 R------QVFQNLISNAIKYSRPGEPPrIEIGAEREggEWVFSVRDNGIGIDPE 443
|
|
| Reg_prop |
pfam07494 |
Two component regulator propeller; A large group of two component regulator proteins appear to ... |
87-110 |
1.62e-03 |
|
Two component regulator propeller; A large group of two component regulator proteins appear to have the same N-terminal structure of 14 tandem repeats. These repeats show homology to pfam01011 and pfam00400 indicating that they are likely to form a beta-propeller. This family has been built with artificially high cut-offs in order to avoid overlaps with other beta-propeller families. The fourteen repeats are likely to form two propellers; it is not clear if these structures are likely to recruit other proteins or interact with DNA.
Pssm-ID: 400050 [Multi-domain] Cd Length: 24 Bit Score: 36.91 E-value: 1.62e-03
|
| SGL |
pfam08450 |
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in ... |
362-532 |
1.73e-03 |
|
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyse diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.
Pssm-ID: 462480 [Multi-domain] Cd Length: 246 Bit Score: 41.09 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 362 GPVWAVAEDAAGTVWVGTESlGLVSYNPATGQRREFRHHPQDPGSLsedfVRA--LCFDRQGRLWVGTQSQGLD-CLEPG 438
Cdd:pfam08450 41 GPVGAIAPRDDGGLIVALKD-GVALLDLATGELTPLADPEDDDWPL----NRFndGKVDPDGRFWFGTMGDDEApGGDPG 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 439 ATrfrhYRHDPAVKNTISEDFI------------RTIY--EGPDGRLWVgtegglnrFEPDKDG--------FTSFRNDP 496
Cdd:pfam08450 116 AL----YRLDPDGKLTRVLDGLtisnglawspdgRTLYfaDSPARKIWA--------YDYDLDGglisnrrvFADFKPGL 183
|
170 180 190
....*....|....*....|....*....|....*..
gi 1280271109 497 ANPRSLsnnFVrvvhqDRTGRVWVGT-GGGGLCCYNP 532
Cdd:pfam08450 184 GRPDGM---AV-----DAEGNVWVARwGGGKVVRFDP 212
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
939-992 |
2.15e-03 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 38.40 E-value: 2.15e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1280271109 939 LLFKEAVNNLAKYAQ--CTEAAITLAYEH--QRLVLTVQDDGVGFDPQAPA------QGGGNGL 992
Cdd:cd16936 3 LAVSEAVTNAVRHAYrhDGPGPVRLELDLdpDRLRVEVTDSGPGFDPLRPAdpdaglREGGRGL 66
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
945-1025 |
3.30e-03 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 41.43 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 945 VNNLAKYAQCTEAAITLAYEHQRLVLTVQDDGVGFDP-----------QAPAQGGGNGLTNMNSR--AAAMKGVLDIQTA 1011
Cdd:PRK11466 570 LSNALRFTDEGSIVLRSRTDGEQWLVEVEDSGCGIDPaklaeifqpfvQVSGKRGGTGLGLTISSrlAQAMGGELSATST 649
|
90
....*....|....
gi 1280271109 1012 PGQGTVLRLNVPLK 1025
Cdd:PRK11466 650 PEVGSCFCLRLPLR 663
|
|
| Reg_prop |
pfam07494 |
Two component regulator propeller; A large group of two component regulator proteins appear to ... |
406-427 |
3.35e-03 |
|
Two component regulator propeller; A large group of two component regulator proteins appear to have the same N-terminal structure of 14 tandem repeats. These repeats show homology to pfam01011 and pfam00400 indicating that they are likely to form a beta-propeller. This family has been built with artificially high cut-offs in order to avoid overlaps with other beta-propeller families. The fourteen repeats are likely to form two propellers; it is not clear if these structures are likely to recruit other proteins or interact with DNA.
Pssm-ID: 400050 [Multi-domain] Cd Length: 24 Bit Score: 35.75 E-value: 3.35e-03
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
860-1026 |
4.01e-03 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 40.69 E-value: 4.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 860 DQATALLDQIGDSSRRMLDAMDDI---------VWTINPAHDSMDDVVARMRSFASDVLEARGIDFTFRADPsiAGLRLN 930
Cdd:COG5002 199 EERREYLEIILEEAERLSRLVNDLldlsrlesgELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPE--DPLLVL 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1280271109 931 MRARReffllFKEAVNNL----AKYAQC-TEAAITLAYEHQRLVLTVQDDGVG---------FDP--QAPA----QGGGN 990
Cdd:COG5002 277 GDPDR-----LEQVLTNLldnaIKYTPEgGTITVSLREEDDQVRISVRDTGIGipeedlpriFERfyRVDKsrsrETGGT 351
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1280271109 991 GL-----TNMnsrAAAMKGVLDIQTAPGQGTVLRLNVPLKS 1026
Cdd:COG5002 352 GLglaivKHI---VEAHGGRIWVESEPGKGTTFTITLPLAR 389
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
733-772 |
5.40e-03 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 37.09 E-value: 5.40e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1280271109 733 YMLENFDPDWVQA----GTKREATYTNLDPGT-YTFRVRATNNDG 772
Cdd:cd00063 37 EYREKGSGDWKEVevtpGSETSYTLTGLKPGTeYEFRVRAVNGGG 81
|
|
| Reg_prop |
pfam07494 |
Two component regulator propeller; A large group of two component regulator proteins appear to ... |
454-477 |
9.50e-03 |
|
Two component regulator propeller; A large group of two component regulator proteins appear to have the same N-terminal structure of 14 tandem repeats. These repeats show homology to pfam01011 and pfam00400 indicating that they are likely to form a beta-propeller. This family has been built with artificially high cut-offs in order to avoid overlaps with other beta-propeller families. The fourteen repeats are likely to form two propellers; it is not clear if these structures are likely to recruit other proteins or interact with DNA.
Pssm-ID: 400050 [Multi-domain] Cd Length: 24 Bit Score: 34.60 E-value: 9.50e-03
|
| |
