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Conserved domains on  [gi|1301403607|gb|PKB68439|]
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MAG: protoheme IX farnesyltransferase [SAR202 cluster bacterium Io17-Chloro-G3]

Protein Classification

CtaA and PT_UbiA_Cox10 domain-containing protein( domain architecture ID 10787840)

CtaA and PT_UbiA_Cox10 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 315-592 8.59e-120

protoheme IX farnesyltransferase; Provisional


:

Pssm-ID: 235293  Cd Length: 296  Bit Score: 356.37  E-value: 8.59e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 315 DYISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYR 394
Cdd:PRK04375   12 DYLALTKPRVISLNLFTALGGMLLAPPGVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKMERTKNRPLVTGRISPR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 395 AAVIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLY 474
Cdd:PRK04375   92 EALIFGLVLGVLGFLLLGLFVNPLAAWLTLAGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLIGWAAVTGSLSWEALI 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 475 LFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPF 554
Cdd:PRK04375  172 LFLIIFLWTPPHFWALAIFRKDDYAAAGIPMLPVVKGIRVTKRQILLYTVLLVAVSLLPVLLGMAGLLYLVVALLLGAWF 251

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1301403607 555 VILAWKLLRAHGDSGAKPLYLYSLAYLAGIFLLLMVDS 592
Cdd:PRK04375  252 LYYAWRLYRKDDRKWARKLFRYSINYLTLLFVALLVDH 289
CtaA COG1612
Heme A synthase [Coenzyme transport and metabolism];
14-296 1.07e-52

Heme A synthase [Coenzyme transport and metabolism];


:

Pssm-ID: 441220  Cd Length: 318  Bit Score: 182.78  E-value: 1.07e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  14 LITLGGIVRVTESGLGCPDWPLCNGKILPPL----------------EYHALIEYSHRTVASLVGFLVILTTIVAWWKAR 77
Cdd:COG1612    25 LVVLGGAVRLTGSGLGCPDWPLCYGSLIPPTseagwqaafkpempleEFKAWIEFGHRLLAGLLGLLILLLAVLAWRRRR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  78 KVRWVILPLSAAVPLVGLAGLLGRNAVLSDLAPEIVTAHLAIAQIIFALvlapLLWYWATTKsahgrqspRGSRKSTLEV 157
Cdd:COG1612   105 RRRRLRWLALLLLLLVGLQGALGGWTVTSGLSPYVVALHLLLALLILAL----LLWLALRLR--------RPDGPLAAAV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 158 PDRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIPNVS--------IGWLHMAHRVIAAIFGLFVGFVA 229
Cdd:COG1612   173 PRRLRRLALAALVLLLLQILLGALVAGNYAGLACPDFPLCNGQWLPHDAepflnfenPVAVQFIHRLGAYLLLLLLLALA 252

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1301403607 230 YLGWqKRSASKIVGRTSAVLIFLLLLQIVVGAANPWLDFTPEIRAAHLSIATAIWGCVIALAIFSRK 296
Cdd:COG1612   253 LRLR-RSRAPRALRRAALLLLALLLLQVLLGIATVLLGLPLLLAVLHQAGAALLLGALVYLLLRLRR 318
 
Name Accession Description Interval E-value
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 315-592 8.59e-120

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 356.37  E-value: 8.59e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 315 DYISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYR 394
Cdd:PRK04375   12 DYLALTKPRVISLNLFTALGGMLLAPPGVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKMERTKNRPLVTGRISPR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 395 AAVIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLY 474
Cdd:PRK04375   92 EALIFGLVLGVLGFLLLGLFVNPLAAWLTLAGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLIGWAAVTGSLSWEALI 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 475 LFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPF 554
Cdd:PRK04375  172 LFLIIFLWTPPHFWALAIFRKDDYAAAGIPMLPVVKGIRVTKRQILLYTVLLVAVSLLPVLLGMAGLLYLVVALLLGAWF 251

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1301403607 555 VILAWKLLRAHGDSGAKPLYLYSLAYLAGIFLLLMVDS 592
Cdd:PRK04375  252 LYYAWRLYRKDDRKWARKLFRYSINYLTLLFVALLVDH 289
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
 301-592 3.97e-117

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 349.82  E-value: 3.97e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 301 ELSSKTKLALQIIEDYISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHR 380
Cdd:COG0109     4 ASASSAASLRSTLRDYLALTKPRIILLLLFTALAGMLLAAGGLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDALMKR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 381 TQNRPVAGDRVSYRAAVIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVG 460
Cdd:COG0109    84 TKNRPLPTGRISPREALIFGLVLGVLGLALLALFVNPLAALLGLLGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLIG 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 461 WVAITGSLGLPPLYLFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVG 540
Cdd:COG0109   164 WAAVTGSLSLEALLLFLIIFLWTPPHFWALALKRRDDYARAGVPMLPVVKGERRTKRQILLYTLLLVPVSLLPYLLGMAG 243

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1301403607 541 EIYFAGAICLGIPFVILAWKLLRAHGDSGAKPLYLYSLAYLAGIFLLLMVDS 592
Cdd:COG0109   244 LIYLVVALVLGAWFLYLAVRLYRRPDRKWARKLFKFSILYLTLLFLALLVDH 295
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 317-587 1.54e-103

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 313.99  E-value: 1.54e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 317 ISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAA 396
Cdd:cd13957     1 LELTKPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 397 VIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLYLF 476
Cdd:cd13957    81 LIFGLVLGILGLALLALFVNPLTALLGLLGIFLYVFVYTPLKKRTTPLNTVIGGIAGAIPPLIGWAAATGSLDLGAWLLF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 477 AIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPFVI 556
Cdd:cd13957   161 LILFLWQPPHFWALAILYRDDYARAGIPMLPVVKGERRTKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGLYFLY 240

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1301403607 557 LAWKLLRAHGDSGAKPLYLYSLAYLAGIFLL 587
Cdd:cd13957   241 LAIKLYRSPDDKWARKLFFASLIYLPLLFLL 271
cyoE_ctaB TIGR01473
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ...
 315-591 2.02e-96

protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273645  Cd Length: 280  Bit Score: 296.08  E-value: 2.02e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 315 DYISLTKPRIVVLLLITALGGMYLAEGGT-PPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSY 393
Cdd:TIGR01473   2 DYLQLTKPRIISLLLITAFAGMWLAPGGAlVNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTGRISP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 394 RAAVIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPL 473
Cdd:TIGR01473  82 REALAFGLLLGVLGVAILAAFVNPLAALLGLFGIFFYVIVYTIWLKRRTPQNTVIGGFAGAVPPLIGWAAVTGSISLGAW 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 474 YLFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIP 553
Cdd:TIGR01473 162 LLFAIIFLWQPPHFWALALKYKDDYRAAGIPMLPVVKGERITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATLLGAL 241

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1301403607 554 FVILAWKLLRAHGD-SGAKPLYLYSLAYLAGIFLLLMVD 591
Cdd:TIGR01473 242 FLYLAFKFYRDPTDrKKARKLFKFSLIYLALLFVALLID 280
CtaA COG1612
Heme A synthase [Coenzyme transport and metabolism];
14-296 1.07e-52

Heme A synthase [Coenzyme transport and metabolism];


Pssm-ID: 441220  Cd Length: 318  Bit Score: 182.78  E-value: 1.07e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  14 LITLGGIVRVTESGLGCPDWPLCNGKILPPL----------------EYHALIEYSHRTVASLVGFLVILTTIVAWWKAR 77
Cdd:COG1612    25 LVVLGGAVRLTGSGLGCPDWPLCYGSLIPPTseagwqaafkpempleEFKAWIEFGHRLLAGLLGLLILLLAVLAWRRRR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  78 KVRWVILPLSAAVPLVGLAGLLGRNAVLSDLAPEIVTAHLAIAQIIFALvlapLLWYWATTKsahgrqspRGSRKSTLEV 157
Cdd:COG1612   105 RRRRLRWLALLLLLLVGLQGALGGWTVTSGLSPYVVALHLLLALLILAL----LLWLALRLR--------RPDGPLAAAV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 158 PDRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIPNVS--------IGWLHMAHRVIAAIFGLFVGFVA 229
Cdd:COG1612   173 PRRLRRLALAALVLLLLQILLGALVAGNYAGLACPDFPLCNGQWLPHDAepflnfenPVAVQFIHRLGAYLLLLLLLALA 252

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1301403607 230 YLGWqKRSASKIVGRTSAVLIFLLLLQIVVGAANPWLDFTPEIRAAHLSIATAIWGCVIALAIFSRK 296
Cdd:COG1612   253 LRLR-RSRAPRALRRAALLLLALLLLQVLLGIATVLLGLPLLLAVLHQAGAALLLGALVYLLLRLRR 318
UbiA pfam01040
UbiA prenyltransferase family;
328-578 1.17e-43

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 156.23  E-value: 1.17e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 328 LLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAAVIFGIILNAAA 407
Cdd:pfam01040   1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 408 FMILFTgVNLLAATLTLSATLFYVvIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLYLFAIIFFWTPPHF 487
Cdd:pfam01040  81 LLLLLL-LNPLTALLGLAALLLYV-LYTLRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 488 WALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPFVILAWKLLRAHGD 567
Cdd:pfam01040 159 LANDLRDREDDRKAGIKTLPVVLGRKAARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPK 238

                         250
                  ....*....|.
gi 1301403607 568 SGAKPLYLYSL 578
Cdd:pfam01040 239 KDAKAFFFLSS 249
COX15-CtaA pfam02628
Cytochrome oxidase assembly protein; This is a family of integral membrane proteins. CtaA is ...
 14-288 2.41e-33

Cytochrome oxidase assembly protein; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast.


Pssm-ID: 460629  Cd Length: 323  Bit Score: 130.11  E-value: 2.41e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  14 LITLGGIVRVTESGLGCPDWPLCNGkILPPL----------------EYH-------------ALIEYSHRTVASLVGFL 64
Cdd:pfam02628  14 VVVLGGYTRLTDSGLSCPDWPPCYG-VLPPLtdedweaefakykqtpEYQlvpgmtlaefkfiFWWEWIHRLLGRLLGLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  65 VILTTIVAWWKARKVRWVILPLSAAVPLVGLAGLLGRNAVLSDL------APEIVTAHLAIAQIIFALVLapllwyWATT 138
Cdd:pfam02628  93 ILVPLVYFWRTGRISRRLKARLLLLLLLGGLQGLLGWWMVTSGLvevprvSPYRLAAHLLLAFLILALLV------WTAL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 139 KSAHGRQSPRGSRKSTlevpdRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIPNV------------- 205
Cdd:pfam02628 167 RLRAPRPSALRLPGPA-----RLRGLALLALALLVLQIALGAWVAGLDAGLAYNTFPLMGGAWIPDDfplcepdwrngfe 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 206 SIGWLHMAHRVIAAIFGLFVGFVAYLGWQKRSASKIVgRTSAVLIFLLLLQIVVGAANPWLDFTPEIRAAHLSIATAIWG 285
Cdd:pfam02628 242 NPVTVQFIHRLGATLVLLALLALAWRLWRRARRPALA-RLAVLLAALLLLQVALGISTVLLGVPLPLAVAHQLGAALLLT 320


                  ...
gi 1301403607 286 CVI 288
Cdd:pfam02628 321 ALV 323
PTZ00127 PTZ00127
cytochrome c oxidase assembly protein; Provisional
 14-260 7.74e-13

cytochrome c oxidase assembly protein; Provisional


Pssm-ID: 240283  Cd Length: 403  Bit Score: 70.47  E-value: 7.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  14 LITLGGIVRVTESGLGCPDWPLcNGKILP----------------PlEYHA--------------LIEYSHRTVASLVGF 63
Cdd:PTZ00127   79 MVVLGGYTRLTESGLSMTDWKF-IGVKPPitqeewekefdkykqfP-EYKQvhygmtleefkkifFWEWLHRMLGRSIGL 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  64 LVILTTIVAWWKARKVRWVILPLSAAVPLVGLAGLLGRNAVLSDL------------APEIVTAHLAIAQIIFALvlapL 131
Cdd:PTZ00127  157 FFGLPLLYFAAKGYLKPRMLKRLSAIGGLGGAQGFVGWWMVKSGLdepltenkkprvSPYRLAAHLFNAFVIYSL----L 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 132 LWywattkSAHGRQSPRGSRKSTLEVPDRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIP----NVSI 207
Cdd:PTZ00127  233 LW------NGLTLILFALPSIAPFPELLKMRLLARGLFALVFLTAMSGAFVAGNDAGLAYNTWPKMGGKFVPddvhNFVP 306

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1301403607 208 GWLHM---------AHRVIAAIFGLFVGFVAYLGwQKRSASKIVGRTSAVLIFLLLLQIVVG 260
Cdd:PTZ00127  307 WYKNFfentavvqfNHRVLAYLTFLSSLGLYYKA-RKLNLPKSVRRLLMALLGALTLQVLLG 367
 
Name Accession Description Interval E-value
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 315-592 8.59e-120

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 356.37  E-value: 8.59e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 315 DYISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYR 394
Cdd:PRK04375   12 DYLALTKPRVISLNLFTALGGMLLAPPGVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKMERTKNRPLVTGRISPR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 395 AAVIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLY 474
Cdd:PRK04375   92 EALIFGLVLGVLGFLLLGLFVNPLAAWLTLAGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLIGWAAVTGSLSWEALI 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 475 LFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPF 554
Cdd:PRK04375  172 LFLIIFLWTPPHFWALAIFRKDDYAAAGIPMLPVVKGIRVTKRQILLYTVLLVAVSLLPVLLGMAGLLYLVVALLLGAWF 251

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1301403607 555 VILAWKLLRAHGDSGAKPLYLYSLAYLAGIFLLLMVDS 592
Cdd:PRK04375  252 LYYAWRLYRKDDRKWARKLFRYSINYLTLLFVALLVDH 289
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
 301-592 3.97e-117

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 349.82  E-value: 3.97e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 301 ELSSKTKLALQIIEDYISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHR 380
Cdd:COG0109     4 ASASSAASLRSTLRDYLALTKPRIILLLLFTALAGMLLAAGGLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDALMKR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 381 TQNRPVAGDRVSYRAAVIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVG 460
Cdd:COG0109    84 TKNRPLPTGRISPREALIFGLVLGVLGLALLALFVNPLAALLGLLGIFFYVVVYTLWLKRRTPQNIVIGGAAGAMPPLIG 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 461 WVAITGSLGLPPLYLFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVG 540
Cdd:COG0109   164 WAAVTGSLSLEALLLFLIIFLWTPPHFWALALKRRDDYARAGVPMLPVVKGERRTKRQILLYTLLLVPVSLLPYLLGMAG 243

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1301403607 541 EIYFAGAICLGIPFVILAWKLLRAHGDSGAKPLYLYSLAYLAGIFLLLMVDS 592
Cdd:COG0109   244 LIYLVVALVLGAWFLYLAVRLYRRPDRKWARKLFKFSILYLTLLFLALLVDH 295
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 317-587 1.54e-103

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 313.99  E-value: 1.54e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 317 ISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAA 396
Cdd:cd13957     1 LELTKPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 397 VIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLYLF 476
Cdd:cd13957    81 LIFGLVLGILGLALLALFVNPLTALLGLLGIFLYVFVYTPLKKRTTPLNTVIGGIAGAIPPLIGWAAATGSLDLGAWLLF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 477 AIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPFVI 556
Cdd:cd13957   161 LILFLWQPPHFWALAILYRDDYARAGIPMLPVVKGERRTKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGLYFLY 240

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1301403607 557 LAWKLLRAHGDSGAKPLYLYSLAYLAGIFLL 587
Cdd:cd13957   241 LAIKLYRSPDDKWARKLFFASLIYLPLLFLL 271
cyoE_ctaB TIGR01473
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ...
 315-591 2.02e-96

protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273645  Cd Length: 280  Bit Score: 296.08  E-value: 2.02e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 315 DYISLTKPRIVVLLLITALGGMYLAEGGT-PPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSY 393
Cdd:TIGR01473   2 DYLQLTKPRIISLLLITAFAGMWLAPGGAlVNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTGRISP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 394 RAAVIFGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPL 473
Cdd:TIGR01473  82 REALAFGLLLGVLGVAILAAFVNPLAALLGLFGIFFYVIVYTIWLKRRTPQNTVIGGFAGAVPPLIGWAAVTGSISLGAW 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 474 YLFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIP 553
Cdd:TIGR01473 162 LLFAIIFLWQPPHFWALALKYKDDYRAAGIPMLPVVKGERITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATLLGAL 241

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1301403607 554 FVILAWKLLRAHGD-SGAKPLYLYSLAYLAGIFLLLMVD 591
Cdd:TIGR01473 242 FLYLAFKFYRDPTDrKKARKLFKFSLIYLALLFVALLID 280
CtaA COG1612
Heme A synthase [Coenzyme transport and metabolism];
14-296 1.07e-52

Heme A synthase [Coenzyme transport and metabolism];


Pssm-ID: 441220  Cd Length: 318  Bit Score: 182.78  E-value: 1.07e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  14 LITLGGIVRVTESGLGCPDWPLCNGKILPPL----------------EYHALIEYSHRTVASLVGFLVILTTIVAWWKAR 77
Cdd:COG1612    25 LVVLGGAVRLTGSGLGCPDWPLCYGSLIPPTseagwqaafkpempleEFKAWIEFGHRLLAGLLGLLILLLAVLAWRRRR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  78 KVRWVILPLSAAVPLVGLAGLLGRNAVLSDLAPEIVTAHLAIAQIIFALvlapLLWYWATTKsahgrqspRGSRKSTLEV 157
Cdd:COG1612   105 RRRRLRWLALLLLLLVGLQGALGGWTVTSGLSPYVVALHLLLALLILAL----LLWLALRLR--------RPDGPLAAAV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 158 PDRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIPNVS--------IGWLHMAHRVIAAIFGLFVGFVA 229
Cdd:COG1612   173 PRRLRRLALAALVLLLLQILLGALVAGNYAGLACPDFPLCNGQWLPHDAepflnfenPVAVQFIHRLGAYLLLLLLLALA 252

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1301403607 230 YLGWqKRSASKIVGRTSAVLIFLLLLQIVVGAANPWLDFTPEIRAAHLSIATAIWGCVIALAIFSRK 296
Cdd:COG1612   253 LRLR-RSRAPRALRRAALLLLALLLLQVLLGIATVLLGLPLLLAVLHQAGAALLLGALVYLLLRLRR 318
UbiA pfam01040
UbiA prenyltransferase family;
328-578 1.17e-43

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 156.23  E-value: 1.17e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 328 LLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAAVIFGIILNAAA 407
Cdd:pfam01040   1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 408 FMILFTgVNLLAATLTLSATLFYVvIYTGWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLYLFAIIFFWTPPHF 487
Cdd:pfam01040  81 LLLLLL-LNPLTALLGLAALLLYV-LYTLRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 488 WALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPFVILAWKLLRAHGD 567
Cdd:pfam01040 159 LANDLRDREDDRKAGIKTLPVVLGRKAARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPK 238

                         250
                  ....*....|.
gi 1301403607 568 SGAKPLYLYSL 578
Cdd:pfam01040 239 KDAKAFFFLSS 249
PLN02776 PLN02776
prenyltransferase
 319-589 1.09e-33

prenyltransferase


Pssm-ID: 215415  Cd Length: 341  Bit Score: 131.41  E-value: 1.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 319 LTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAAVI 398
Cdd:PLN02776    1 LSKARLSALVVATSGAGFVLGSGEAIDLPGLGWTCAGTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISVPHAVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 399 FGIILNAAAFMILFTGVNLLAATLTLSATLFYVVIYTgWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLYLFAI 478
Cdd:PLN02776   81 WAVVVGAAGVALLAYKTNMLTAGLGAGNILLYAFVYT-PLKQIHPANTWVGAVVGAIPPLMGWAAASGQLDAGAMVLAAA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 479 IFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAA-TAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPFVIL 557
Cdd:PLN02776  160 LYFWQMPHFMALAYMCRDDYAAGGYRMLSLADATGRrTALVALRNCLYLAPLGFLAYDWGVTSSPFALEAALLTAYLAAS 239

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1301403607 558 AWKLLRAHGDSGAKPLYLYSLAYLAgIFLLLM 589
Cdd:PLN02776  240 AASFYREPTNANARKMFHGSLLYLP-AFMALL 270
COX15-CtaA pfam02628
Cytochrome oxidase assembly protein; This is a family of integral membrane proteins. CtaA is ...
 14-288 2.41e-33

Cytochrome oxidase assembly protein; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast.


Pssm-ID: 460629  Cd Length: 323  Bit Score: 130.11  E-value: 2.41e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  14 LITLGGIVRVTESGLGCPDWPLCNGkILPPL----------------EYH-------------ALIEYSHRTVASLVGFL 64
Cdd:pfam02628  14 VVVLGGYTRLTDSGLSCPDWPPCYG-VLPPLtdedweaefakykqtpEYQlvpgmtlaefkfiFWWEWIHRLLGRLLGLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  65 VILTTIVAWWKARKVRWVILPLSAAVPLVGLAGLLGRNAVLSDL------APEIVTAHLAIAQIIFALVLapllwyWATT 138
Cdd:pfam02628  93 ILVPLVYFWRTGRISRRLKARLLLLLLLGGLQGLLGWWMVTSGLvevprvSPYRLAAHLLLAFLILALLV------WTAL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 139 KSAHGRQSPRGSRKSTlevpdRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIPNV------------- 205
Cdd:pfam02628 167 RLRAPRPSALRLPGPA-----RLRGLALLALALLVLQIALGAWVAGLDAGLAYNTFPLMGGAWIPDDfplcepdwrngfe 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 206 SIGWLHMAHRVIAAIFGLFVGFVAYLGWQKRSASKIVgRTSAVLIFLLLLQIVVGAANPWLDFTPEIRAAHLSIATAIWG 285
Cdd:pfam02628 242 NPVTVQFIHRLGATLVLLALLALAWRLWRRARRPALA-RLAVLLAALLLLQVALGISTVLLGVPLPLAVAHQLGAALLLT 320


                  ...
gi 1301403607 286 CVI 288
Cdd:pfam02628 321 ALV 323
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 319-588 4.73e-25

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 104.93  E-value: 4.73e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 319 LTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAAVI 398
Cdd:COG0382     9 LDRPIGILLLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGRISLREALL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 399 FGIILNAAAFMILFTgVNLLAATLTLSAtLFYVVIYTGWLKRST-TQNIVIGGAAGAVPPMvGWVAITGSLGLPPLYLFA 477
Cdd:COG0382    89 LAIVLLLLALALALL-LNPLTFLLALAA-LALAWAYSLFLKRFTlLGNLVLGLLFGLGILM-GFAAVTGSLPLSAWLLAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 478 IIFFWTpphfWALALL-----IKDDyARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGI 552
Cdd:COG0382   166 AAFLWT----LAYDTIydledREGD-RKIGIKTLAILFGVRDALIIAGVLYALAVLLLLLLGLLAGLGLLYLLGLLAALL 240

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1301403607 553 PFVILAWKLLRAHGDSGAKPLYLYSLAYLAGIFLLL 588
Cdd:COG0382   241 LLYLSQLWLLRPRKKDPARALKLFKLNMLLGLLLFL 276
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 319-559 3.28e-16

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 79.05  E-value: 3.28e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 319 LTKPRIVVLLLITALGGMYLAEGGTPP--LSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAA 396
Cdd:cd13959     3 LDKPIGTLLLLPPALWGLLLAAGGLPLplLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVKEA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 397 VIFGIILNAAAFMILFTgVNLLAATLTLSATLFyVVIYTgWLKRST--TQniVIGGAAGAVPPMVGWVAITGSLGLPPLY 474
Cdd:cd13959    83 LLFLAVQLLLGLALLLQ-LNPLTILLSPIALLL-VLIYP-LMKRFTywPQ--LVLGLAFGWGPLMGWAAVTGSLPLPALL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 475 LFAIIFFWTpphfwAL-----ALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAvGEIYFAGAIC 549
Cdd:cd13959   158 LYLAVIFWT-----AGydtiyAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGL-GWPYYLGLGA 231

                         250
                  ....*....|
gi 1301403607 550 LGIPFVILAW 559
Cdd:cd13959   232 AAHLLWQEHR 241
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 317-589 3.71e-14

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 72.77  E-value: 3.71e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 317 ISLTKPRIVVLLLITAL-GGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQlmHRTQNRPVAGDRVSYRA 395
Cdd:cd13956     1 LRLMRPYTLLYVLAPALaGAALAGAFAGPLPALLLLALLAVFLGAGAGYALNDYTDRELDA--INKPDRPLPSGRLSPRQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 396 AVIFGIILNAAAFmILFTGVNLLAATLTLsATLFYVVIYTGWLKRSTT-QNIVIGGAAGAVPPMVGWVAITGSLGLPPLY 474
Cdd:cd13956    79 ALAFAAALLLVGL-ALALALGPLALLLLL-AGLLLGLAYSLGLKRLKLgGWGVLGYATGLALLPGLGAVAAGGLVPLALL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 475 LFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPF 554
Cdd:cd13956   157 LALVFLLLGLGINLYNDLPDVEGDRAAGIRTLPVRLGPRRARRLAAGLLLAALILVVLLAVAGLLGPLALLALLAVALLA 236

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1301403607 555 VILAWKLLRAHGDSGAKPLYLYSLAYLAGIFLLLM 589
Cdd:cd13956   237 LRARFARADRLPALPRGFLLLAVYRLLLFAALLLA 271
PTZ00127 PTZ00127
cytochrome c oxidase assembly protein; Provisional
 14-260 7.74e-13

cytochrome c oxidase assembly protein; Provisional


Pssm-ID: 240283  Cd Length: 403  Bit Score: 70.47  E-value: 7.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  14 LITLGGIVRVTESGLGCPDWPLcNGKILP----------------PlEYHA--------------LIEYSHRTVASLVGF 63
Cdd:PTZ00127   79 MVVLGGYTRLTESGLSMTDWKF-IGVKPPitqeewekefdkykqfP-EYKQvhygmtleefkkifFWEWLHRMLGRSIGL 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607  64 LVILTTIVAWWKARKVRWVILPLSAAVPLVGLAGLLGRNAVLSDL------------APEIVTAHLAIAQIIFALvlapL 131
Cdd:PTZ00127  157 FFGLPLLYFAAKGYLKPRMLKRLSAIGGLGGAQGFVGWWMVKSGLdepltenkkprvSPYRLAAHLFNAFVIYSL----L 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 132 LWywattkSAHGRQSPRGSRKSTLEVPDRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIP----NVSI 207
Cdd:PTZ00127  233 LW------NGLTLILFALPSIAPFPELLKMRLLARGLFALVFLTAMSGAFVAGNDAGLAYNTWPKMGGKFVPddvhNFVP 306

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1301403607 208 GWLHM---------AHRVIAAIFGLFVGFVAYLGwQKRSASKIVGRTSAVLIFLLLLQIVVG 260
Cdd:PTZ00127  307 WYKNFfentavvqfNHRVLAYLTFLSSLGLYYKA-RKLNLPKSVRRLLMALLGALTLQVLLG 367
ubiA PRK12886
prenyltransferase; Reviewed
 310-587 6.05e-12

prenyltransferase; Reviewed


Pssm-ID: 237247  Cd Length: 291  Bit Score: 66.64  E-value: 6.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 310 LQIIEDYISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGD 389
Cdd:PRK12886    5 LTKLKVFLEMIKFSHTLFALPFAGIGAVLAALGLPGASQLDWILMAMVGARTAAMGFNRLIDAEIDARNPRTAGRAIPAG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 390 RVSYRAAVIFgIILNAAAFMILFTGVNLLAATLTLSAtLFYVVIYTgWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLG 469
Cdd:PRK12886   85 LISKGSAILF-IVLSSLLMLFAAWFLNPLCLYLSPPA-LFFLLLYS-YCKRFTALAHVVLGFCLALAPLGAWIAIRGTIE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 470 LPPLYLFAIIFFWTPPHFWALALLIKDDYARAGVPMLPVVQG-NAATAKSVMLHTIILVSLTILFYTTEaVGEIYFAGAI 548
Cdd:PRK12886  162 LPAILLGLAVLFWVAGFDILYALQDLEFDRKEGLHSIPAKLGvNGSLWIARVFHLLMIGFLFALGISAG-LGPWFLAGLA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1301403607 549 CLGIpFVILAWKLLRaHGDSGAKPLYLYSL-AYLAGIFLL 587
Cdd:PRK12886  241 VTGI-LLLYEHWLLR-GGDLTRLDAAFFNMnGYISVTLFA 278
CtaA COG1612
Heme A synthase [Coenzyme transport and metabolism];
157-298 5.82e-11

Heme A synthase [Coenzyme transport and metabolism];


Pssm-ID: 441220  Cd Length: 318  Bit Score: 64.14  E-value: 5.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 157 VPDRFGPLVLLTFPAIFITLLTGSYVVGEGAGTACPSWPFCDSGLIPNVSI-----------------GWLHMAHRVIAA 219
Cdd:COG1612     7 SRRALRRLALLTLVLTFLLVVLGGAVRLTGSGLGCPDWPLCYGSLIPPTSEagwqaafkpempleefkAWIEFGHRLLAG 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1301403607 220 IFGLFVGFVAYLGWQKRSASKIVGRTSAVLIFLLLLQIVVGAANPWLDFTPEIRAAHLSIATAIWGCVIALAIFSRKAE 298
Cdd:COG1612    87 LLGLLILLLAVLAWRRRRRRRRLRWLALLLLLLVGLQGALGGWTVTSGLSPYVVALHLLLALLILALLLWLALRLRRPD 165
PT_UbiA_DGGGPS cd13961
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ...
 316-563 1.13e-09

Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260124  Cd Length: 270  Bit Score: 59.44  E-value: 1.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 316 YISLTKPRIVVLLLITALGGMYLAEGGTPPLSL--VLLVMVGGALGSGGAQAINHSLDKDIDQLMHrtQNRPVAGDRVSY 393
Cdd:cd13961     2 YLELIRPPNLLMAALAQYLGALFALGPLLSLNDleLLLLFLSVFLIAAAGYIINDYFDVEIDRINK--PDRPIPSGRISR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 394 RAAVIFGIILNAAAFMILFTgVNLLAATLTLSATLFyVVIYTGWLKRST-TQNIVIGGAAGAVPPMVGwvAITGSLGLPP 472
Cdd:cd13961    80 REALILSILLNALGLILAFL-LSPLALLIALLNSLL-LWLYSHKLKRTPlIGNLLVALLTGLPFLFGG--LAAGNLLLII 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 473 LYLFAIIFFWTpphfwaLAL-LIKD--DY---ARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAG 546
Cdd:cd13961   156 LLLALFAFLIT------LGReIVKDieDVegdRAEGARTLPIVYGIKKAKKIAALLLLLAILLSPLPYLLGGLGILYLIL 229

                         250
                  ....*....|....*..
gi 1301403607 547 AICLGIPFVILAWKLLR 563
Cdd:cd13961   230 IIIADLLFLYSAIRLAK 246
ubiA PRK12874
4-hydroxybenzoate polyprenyltransferase;
363-483 2.54e-07

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 237242  Cd Length: 291  Bit Score: 52.70  E-value: 2.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 363 AQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAAVIFgIILNAAAFMILFTGVNLLAATLTLsATLFYVVIYTGWLKRST 442
Cdd:PRK12874   63 AMAFNRLVDRDIDKDNPRTANRPSVDGRISVKSMVLF-IVLNALIFIGVSYFINPLAFKLSF-PFLIVLGGYSYFKRFSS 140

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1301403607 443 TQNIVIGGAAGaVPPMVGWVAITGSLGLPPLYLFAIIFFWT 483
Cdd:PRK12874  141 LAHLVLGLSLG-LAPIAGVVAVLGEIPLWSVFLALGVMFWV 180
ubiA PRK12888
4-hydroxybenzoate octaprenyltransferase;
329-555 8.46e-07

4-hydroxybenzoate octaprenyltransferase;


Pssm-ID: 183814  Cd Length: 284  Bit Score: 50.87  E-value: 8.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 329 LITALGGMYLAeGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAAVIfGIILNAAAF 408
Cdd:PRK12888   22 YIAALTAMFAS-DGSVHWADLLLVTVAMVGARTFAMAANRIIDREIDARNPRTAGRELVTGAVSVRTAWT-GALVALAVF 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 409 MILFTGVNLLAATLTLSATLFYVVIYTGwlKRSTTQNIVIGGAAGAVPPMVGWVAITGSLGLPPLYLFAIIFFWTPPHFW 488
Cdd:PRK12888  100 LGAAALLNPLCLALAPLAVAPLVVYPYA--KRFTNFPHAILGLAQAVGPVGAWIAVTGTWSWPAVLLGLAVGLWIGGFDL 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1301403607 489 ALALLIKDDYARAGVPMLPVVQG-NAATAKSVMLHTIIlVSLTILFYTTEAVGEIYFAGAICLGIPFV 555
Cdd:PRK12888  178 IYACQDAEVDRRIGVRSVPARFGvRAALWASRVAHVVT-FALFVWFGLAVGFGALWWIGLAITAGAFA 244
ubiA PRK12873
4-hydroxybenzoate polyprenyltransferase;
320-430 3.44e-06

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 171787 [Multi-domain]  Cd Length: 294  Bit Score: 49.27  E-value: 3.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 320 TKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAAVIF 399
Cdd:PRK12873   17 NKPTGRLILLIPAGWSLWLTPSAPPSLLLLLLIILGGLAVSGAGCIANDLWDRRIDRKVERTKNRPLARGKISLKTAYSL 96

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1301403607 400 GIILNAAAFMILFT------GVNLLAATLTLSATLFY 430
Cdd:PRK12873   97 LIVLLLLSLFVVLSlpqpsrNLCLSLAFLALPPILIY 133
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
 319-503 9.03e-06

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 47.76  E-value: 9.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 319 LTKPRIVVLLLITALGGMYLAE--GGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHRTQNRPVAGDRVSYRAA 396
Cdd:PLN02809   15 LDKPIGTWLLAWPCMWSIALAAppGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGALTPFQG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 397 VIFGIILNAAAFMILFTGVN---LLAAtltlsATLFYVVIYTgWLKRSTTQNIVIGGAAGAVPPMVGWVAITGSLG---L 470
Cdd:PLN02809   95 VGFLGAQLLLGLGILLQLNNysrILGA-----SSLLLVFTYP-LMKRFTFWPQAFLGLTFNWGALLGWAAVKGSLDpavV 168

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1301403607 471 PPLYLFAIifFWTPPHFWALALLIKDDYARAGV 503
Cdd:PLN02809  169 LPLYASGV--CWTLVYDTIYAHQDKEDDLKVGV 199
ubiA PRK12882
prenyltransferase; Reviewed
 316-440 6.12e-05

prenyltransferase; Reviewed


Pssm-ID: 183811  Cd Length: 276  Bit Score: 44.96  E-value: 6.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 316 YISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLmhRTQNRPVAGDRVSYRA 395
Cdd:PRK12882    7 YLELTRPVNAVVAGVAAFIGAFIAGGILSSPSLTGLAFAAVFLATGAGNAINDYFDREIDRI--NRPDRPIPSGAVSPRG 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1301403607 396 AVIFGIILNAAAFMILFTgVNLLAATLTLSATLFyVVIYTGWLKR 440
Cdd:PRK12882   85 ALAFSILLFAAGVALAFL-LPPLCLAIALFNSLL-LVLYAETLKG 127
PRK09573 PRK09573
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
 313-571 3.75e-04

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed


Pssm-ID: 181963  Cd Length: 279  Bit Score: 42.64  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 313 IEDYISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLMHrtQNRPVAGDRVS 392
Cdd:PRK09573    3 IKAYFELIRPKNCIGASIGAIIGYLIASNFKIDLKGIILAALVVFLVCAGGNVINDIYDIEIDKINK--PERPIPSGRIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 393 YRAAVIFGIILNAAAfMILFTGVNLLAATLTLSATLFyVVIYTGWLKRsttqNIVIGGAagAVPPMVGWVAITGSLG--- 469
Cdd:PRK09573   81 LKEAKIFSITLFIVG-LILSIFINIYAFLIALLNSIL-LYLYAKDLKK----TGLIGNL--IVAYLTGLSFIFGGLAvfn 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 470 -LPPLYLFAIIFFWTpphfWALAlLIKD--DY---ARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIY 543
Cdd:PRK09573  153 vLRIIILFLCAFFST----WSRE-IVKDieDIegdLKENVITLPIKYGIKKSWYIAKILLILAIVLSPLPYFLGIFGIYY 227

                         250       260
                  ....*....|....*....|....*...
gi 1301403607 544 FAGAICLGIPFVILAWKLLRAHGDSGAK 571
Cdd:PRK09573  228 LIVVIICDILFIIAMLILLKNPSIEGAS 255
ubiA PRK12884
prenyltransferase; Reviewed
 316-565 6.02e-04

prenyltransferase; Reviewed


Pssm-ID: 183812  Cd Length: 279  Bit Score: 41.87  E-value: 6.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 316 YISLTKPRIVVLLLITALGGMYLAEGGTPPLSlVLLVMVGGALGSGGAQAINHSLDKDIDqLMHRTqNRPVAGDRVSYRA 395
Cdd:PRK12884    7 YLELLRPEHGLMAGIAVVLGAIIALGGLPLDE-ALLGFLTAFFASGSANALNDYFDYEVD-RINRP-DRPIPSGRISRRE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 396 AVIFGIILNAAAFMILFTgVNLLAATLTLSATLFyVVIYTGWLKRS-TTQNIVIGGAAGAvPPMVGWVAITGSLGLpPLY 474
Cdd:PRK12884   84 ALLLAILLFILGLIAAYL-ISPLAFLVVILVSVL-GILYNWKLKEYgLIGNLYVAFLTGM-TFIFGGIAVGELNEA-VIL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 475 LFAIIFFWTpphfwaLALLIKDDY------ARAGVPMLPVVQGNAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAI 548
Cdd:PRK12884  160 LAAMAFLMT------LGREIMKDIedvegdRLRGARTLAILYGEKIAGRIAAALFILAVLLSPLPYLFGIFNILYLAPVL 233

                         250
                  ....*....|....*..
gi 1301403607 549 CLGIPFVILAWKLLRAH 565
Cdd:PRK12884  234 VADLIFLYSAYSLLRSQ 250
ubiA PRK12883
prenyltransferase UbiA-like protein; Reviewed
 316-470 1.14e-03

prenyltransferase UbiA-like protein; Reviewed


Pssm-ID: 171796  Cd Length: 277  Bit Score: 41.25  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 316 YISLTKPRIVVLLLITALGGMYLAEGGTPPLSLVLLVMVGGALGSGGAQAINHSLDKDIDQLmhRTQNRPVAGDRVSYRA 395
Cdd:PRK12883    6 FIEITRPHNCILAGIVGILGSLVALGGIPPIKTLILIFLVVYLGCSGGNTINDYFDYEIDKI--NRPNRPLPRGAMSRKA 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1301403607 396 AVIFGIILNAAAFMI-LFTGVNLLAATLTLSATLFyvvIYTGWLK-RSTTQNIVIGGAAGAVpPMVGWVAItGSLGL 470
Cdd:PRK12883   84 ALYYSLLLFAVGLALaYLINIEAFLFALGAYVLMF---LYAWKLKpLPFIGNVVVALLTGAT-PIYGAIAV-GRIGL 155
PT_UbiA_chlorophyll cd13958
Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of ...
 348-563 2.63e-03

Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of chlorophyll (Chl) biosynthesis, the addition of the tetraprenyl (phytyl or geranylgeranyl) side chain. In plant chloroplast, the chlorophyll synthase is located in thylakoid membrane and has been shown to also have a regulatory or channeling function. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260121  Cd Length: 277  Bit Score: 39.91  E-value: 2.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 348 LVLLVMVGGALGSGGAQAINHSLDKDIDQLmhRTQNRPVAGDRVSYRAAVIFGIILNAAAFMILFTGVNLLAATLTLsAT 427
Cdd:cd13958    37 LLLGMLLAGPLLTGTSQTINDYYDREVDAI--NEPYRPIPSGRISEREALWNIWVLLLLSLLVALFLDGPWVFAAAV-VG 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1301403607 428 LFYVVIYTG---WLKRST-TQNIVIGGAAGAVPPMVGWVAITGSLGLPPLYLfAIIFFWTpphfwALALLIKDDY----- 498
Cdd:cd13958   114 LVLAYIYSApplKLKQNGwWGNAAVGLSYEGLPWWAGAAAFAGLLTWESLAL-ALLYSIG-----AHGIMTLNDFksieg 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1301403607 499 -ARAGVPMLPVVQGnAATAKSVMLHTIILVSLTILFYTTEAVGEIYFAGAICLGIPFVILAWKLLR 563
Cdd:cd13958   188 dRQLGLRSLPVALG-VDTAAWIACGVIDVPQLAVAALLLAWGETWYAAVVGALLLAQIPLQFKLLL 252
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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