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Conserved domains on  [gi|1308505515|gb|PKL29674|]
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carbohydrate kinase [Spirochaetae bacterium HGW-Spirochaetae-2]

Protein Classification

carbohydrate kinase family protein( domain architecture ID 399)

carbohydrate kinase family protein that accepts a wide variety of substrates, including carbohydrates and aromatic small molecules, all being phosphorylated at a hydroxyl group; belongs to the ribokinase/pfkB sugar kinase superfamily

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ribokinase_pfkB_like super family cl00192
ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including ...
 1-269 6.90e-50

ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, 2-dehydro-3-deoxygluconokinase, 1-phosphofructokinase, the minor 6-phosphofructokinase (PfkB), inosine-guanosine kinase, and adenosine kinase. Even though there is a high degree of structural conservation within this superfamily, their multimerization level varies widely, monomeric (e.g. adenosine kinase), dimeric (e.g. ribokinase), and trimeric (e.g THZ kinase).


The actual alignment was detected with superfamily member cd01167:

Pssm-ID: 469648 [Multi-domain]  Cd Length: 295  Bit Score: 167.43  E-value: 6.90e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLIGSSNSEGQPcFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDVR 80
Cdd:cd01167     1 KVVCFGEALIDFIPEGSGAPET-FTKAPGGAPANVAVALARLGGKAAFIGKVGDDEFGDFLLETLKEAGVDTRGIQFDPA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  81 ENSMIGFAKLDAKGAATYSFYIDGTtvtvltADEIVEAIEPLATL---RYLHVGSVSIALDSSGEQILSALKRLKARP-F 156
Cdd:cd01167    80 APTTLAFVTLDADGERSFEFYRGPA------ADLLLDTELNPDLLseaDILHFGSIALASEPSRSALLELLEAAKKAGvL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 157 VFFDPNVRPSVIGNFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLLELGASHVVLTKGKDGLQWISKSGl 236
Cdd:cd01167   154 ISFDPNLRPPLWRDEEEARERIAELLELADIVKLSDEELELLFGEEDPEEIAALLLLFGLKLVLVTRGADGALLYTKGG- 232

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1308505515 237 DIRVPAIDNPIVDTVGAGDTVSGALLTYLEEHD 269
Cdd:cd01167   233 VGEVPGIPVEVVDTTGAGDAFVAGLLAQLLSRG 265
 
Name Accession Description Interval E-value
bac_FRK cd01167
Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for ...
 1-269 6.90e-50

Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.


Pssm-ID: 238572 [Multi-domain]  Cd Length: 295  Bit Score: 167.43  E-value: 6.90e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLIGSSNSEGQPcFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDVR 80
Cdd:cd01167     1 KVVCFGEALIDFIPEGSGAPET-FTKAPGGAPANVAVALARLGGKAAFIGKVGDDEFGDFLLETLKEAGVDTRGIQFDPA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  81 ENSMIGFAKLDAKGAATYSFYIDGTtvtvltADEIVEAIEPLATL---RYLHVGSVSIALDSSGEQILSALKRLKARP-F 156
Cdd:cd01167    80 APTTLAFVTLDADGERSFEFYRGPA------ADLLLDTELNPDLLseaDILHFGSIALASEPSRSALLELLEAAKKAGvL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 157 VFFDPNVRPSVIGNFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLLELGASHVVLTKGKDGLQWISKSGl 236
Cdd:cd01167   154 ISFDPNLRPPLWRDEEEARERIAELLELADIVKLSDEELELLFGEEDPEEIAALLLLFGLKLVLVTRGADGALLYTKGG- 232

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1308505515 237 DIRVPAIDNPIVDTVGAGDTVSGALLTYLEEHD 269
Cdd:cd01167   233 VGEVPGIPVEVVDTTGAGDAFVAGLLAQLLSRG 265
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
 1-265 1.19e-41

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 146.18  E-value: 1.19e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLIGSSNSEGQPC-------FYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMV 73
Cdd:COG0524     1 DVLVIGEALVDLVARVDRLPKGGetvlagsFRRSPGGAAANVAVALARLGARVALVGAVGDDPFGDFLLAELRAEGVDTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  74 PKFQDVRENSMIGFAKLDAKGAATYSFY--IDGTtvtvLTADEIVEAIepLATLRYLHVGSVSIALDSSGEQILSALKRL 151
Cdd:COG0524    81 GVRRDPGAPTGLAFILVDPDGERTIVFYrgANAE----LTPEDLDEAL--LAGADILHLGGITLASEPPREALLAALEAA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 152 KARP-FVFFDPNVRPSVignFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLLELGASHVVLTKGKDGLQW 230
Cdd:COG0524   155 RAAGvPVSLDPNYRPAL---WEPARELLRELLALVDILFPNEEEAELLTGETDPEEAAAALLARGVKLVVVTLGAEGALL 231

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1308505515 231 ISKSGLdIRVPAIDNPIVDTVGAGDTVSGALLTYL 265
Cdd:COG0524   232 YTGGEV-VHVPAFPVEVVDTTGAGDAFAAGFLAGL 265
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
 1-270 4.95e-28

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 109.74  E-value: 4.95e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLIGssNSEGQP-------CFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKmv 73
Cdd:pfam00294   1 KVVVIGEANIDLIG--NVEGLPgelvrvsTVEKGPGGKGANVAVALARLGGDVAFIGAVGDDNFGEFLLQELKKEGVD-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  74 PKFQDVRENSMIGFAKLDAKGAATYSFYIDGTTVTVLTADEIVEAIEPLATLRYLHV-GSVSIALDSSGEQILSALKRLK 152
Cdd:pfam00294  77 TDYVVIDEDTRTGTALIEVDGDGERTIVFNRGAAADLTPEELEENEDLLENADLLYIsGSLPLGLPEATLEELIEAAKNG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 153 arpfVFFDPNVRPSVIGNFETYRkrvvEVARLASLIKLSHEDLELLF--PDSSVKDGISCLLEL---GASHVVLTKGKDG 227
Cdd:pfam00294 157 ----GTFDPNLLDPLGAAREALL----ELLPLADLLKPNEEELEALTgaKLDDIEEALAALHKLlakGIKTVIVTLGADG 228

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1308505515 228 LQWISKSGLDIRVPAIDNPIVDTVGAGDTVSGALLT-YLEEHDI 270
Cdd:pfam00294 229 ALVVEGDGEVHVPAVPKVKVVDTTGAGDSFVGGFLAgLLAGKSL 272
PRK09434 PRK09434
aminoimidazole riboside kinase; Provisional
 5-270 9.35e-23

aminoimidazole riboside kinase; Provisional


Pssm-ID: 236514 [Multi-domain]  Cd Length: 304  Bit Score: 95.77  E-value: 9.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   5 MGEALIDLIgssnSEGQPCFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDVRENSM 84
Cdd:PRK09434    8 LGDAVVDLI----PEGENRYLKCPGGAPANVAVGIARLGGESGFIGRVGDDPFGRFMQQTLQDEGVDTTYLRLDPAHRTS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  85 IGFAKLDAKGAATYSFYIDGTTVTVLTADEIveaiEPLATLRYLHVGSVSIALDSSGEQILSALKRLK-ARPFVFFDPNV 163
Cdd:PRK09434   84 TVVVDLDDQGERSFTFMVRPSADLFLQPQDL----PPFRQGEWLHLCSIALSAEPSRSTTFEAMRRIKaAGGFVSFDPNL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 164 RPSVIGNFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLL-ELGASHVVLTKGKDG-LQWISKSGLDIRVP 241
Cdd:PRK09434  160 REDLWQDEAELRECLRQALALADVVKLSEEELCFLSGTSQLEDAIYALAdRYPIALLLVTLGAEGvLVHTRGQVQHFPAP 239

                         250       260
                  ....*....|....*....|....*....
gi 1308505515 242 AIDnpIVDTVGAGDTVSGALLTYLEEHDI 270
Cdd:PRK09434  240 SVD--PVDTTGAGDAFVAGLLAGLSQAGL 266
D_ribokin_bact TIGR02152
ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose ...
 41-267 7.20e-12

ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars]


Pssm-ID: 274000 [Multi-domain]  Cd Length: 293  Bit Score: 64.93  E-value: 7.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  41 RLDSDVLYIGKLSSDMFGKQMQEYFSAN--NVKMVpkFQDVRENSMIGFAKLDAKGAAtySFYIDGTTVTVLTADEIVEA 118
Cdd:TIGR02152  43 RLGAEVSMIGKVGDDAFGDELLENLKSNgiDTEYV--GTVKDTPTGTAFITVDDTGEN--RIVVVAGANAELTPEDIDAA 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 119 IEPLATLRYlhvgsVSIALDSSGEQILSALKRLKARPF-VFFDPnvRPsVIGNFETyrkrvvEVARLASLIKLSHEDLEL 197
Cdd:TIGR02152 119 EALIAESDI-----VLLQLEIPLETVLEAAKIAKKHGVkVILNP--AP-AIKDLDD------ELLSLVDIITPNETEAEI 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1308505515 198 LFPDS-----SVKDGISCLLELGASHVVLTKGKDGLQWISKSGLDIrVPAIDNPIVDTVGAGDTVSGALLTYLEE 267
Cdd:TIGR02152 185 LTGIEvtdeeDAEKAAEKLLEKGVKNVIITLGSKGALLVSKDESKL-IPAFKVKAVDTTAAGDTFNGAFAVALAE 258
 
Name Accession Description Interval E-value
bac_FRK cd01167
Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for ...
 1-269 6.90e-50

Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.


Pssm-ID: 238572 [Multi-domain]  Cd Length: 295  Bit Score: 167.43  E-value: 6.90e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLIGSSNSEGQPcFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDVR 80
Cdd:cd01167     1 KVVCFGEALIDFIPEGSGAPET-FTKAPGGAPANVAVALARLGGKAAFIGKVGDDEFGDFLLETLKEAGVDTRGIQFDPA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  81 ENSMIGFAKLDAKGAATYSFYIDGTtvtvltADEIVEAIEPLATL---RYLHVGSVSIALDSSGEQILSALKRLKARP-F 156
Cdd:cd01167    80 APTTLAFVTLDADGERSFEFYRGPA------ADLLLDTELNPDLLseaDILHFGSIALASEPSRSALLELLEAAKKAGvL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 157 VFFDPNVRPSVIGNFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLLELGASHVVLTKGKDGLQWISKSGl 236
Cdd:cd01167   154 ISFDPNLRPPLWRDEEEARERIAELLELADIVKLSDEELELLFGEEDPEEIAALLLLFGLKLVLVTRGADGALLYTKGG- 232

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1308505515 237 DIRVPAIDNPIVDTVGAGDTVSGALLTYLEEHD 269
Cdd:cd01167   233 VGEVPGIPVEVVDTTGAGDAFVAGLLAQLLSRG 265
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
 1-265 1.19e-41

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 146.18  E-value: 1.19e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLIGSSNSEGQPC-------FYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMV 73
Cdd:COG0524     1 DVLVIGEALVDLVARVDRLPKGGetvlagsFRRSPGGAAANVAVALARLGARVALVGAVGDDPFGDFLLAELRAEGVDTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  74 PKFQDVRENSMIGFAKLDAKGAATYSFY--IDGTtvtvLTADEIVEAIepLATLRYLHVGSVSIALDSSGEQILSALKRL 151
Cdd:COG0524    81 GVRRDPGAPTGLAFILVDPDGERTIVFYrgANAE----LTPEDLDEAL--LAGADILHLGGITLASEPPREALLAALEAA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 152 KARP-FVFFDPNVRPSVignFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLLELGASHVVLTKGKDGLQW 230
Cdd:COG0524   155 RAAGvPVSLDPNYRPAL---WEPARELLRELLALVDILFPNEEEAELLTGETDPEEAAAALLARGVKLVVVTLGAEGALL 231

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1308505515 231 ISKSGLdIRVPAIDNPIVDTVGAGDTVSGALLTYL 265
Cdd:COG0524   232 YTGGEV-VHVPAFPVEVVDTTGAGDAFAAGFLAGL 265
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
 1-270 4.95e-28

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 109.74  E-value: 4.95e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLIGssNSEGQP-------CFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKmv 73
Cdd:pfam00294   1 KVVVIGEANIDLIG--NVEGLPgelvrvsTVEKGPGGKGANVAVALARLGGDVAFIGAVGDDNFGEFLLQELKKEGVD-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  74 PKFQDVRENSMIGFAKLDAKGAATYSFYIDGTTVTVLTADEIVEAIEPLATLRYLHV-GSVSIALDSSGEQILSALKRLK 152
Cdd:pfam00294  77 TDYVVIDEDTRTGTALIEVDGDGERTIVFNRGAAADLTPEELEENEDLLENADLLYIsGSLPLGLPEATLEELIEAAKNG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 153 arpfVFFDPNVRPSVIGNFETYRkrvvEVARLASLIKLSHEDLELLF--PDSSVKDGISCLLEL---GASHVVLTKGKDG 227
Cdd:pfam00294 157 ----GTFDPNLLDPLGAAREALL----ELLPLADLLKPNEEELEALTgaKLDDIEEALAALHKLlakGIKTVIVTLGADG 228

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1308505515 228 LQWISKSGLDIRVPAIDNPIVDTVGAGDTVSGALLT-YLEEHDI 270
Cdd:pfam00294 229 ALVVEGDGEVHVPAVPKVKVVDTTGAGDSFVGGFLAgLLAGKSL 272
KdgK cd01166
2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form ...
 2-270 5.72e-26

2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.


Pssm-ID: 238571 [Multi-domain]  Cd Length: 294  Bit Score: 104.19  E-value: 5.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   2 IAFMGEALIDLIGSSNSEGQPC--FYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNV--KMVPKFQ 77
Cdd:cd01166     2 VVTIGEVMVDLSPPGGGRLEQAdsFRKFFGGAEANVAVGLARLGHRVALVTAVGDDPFGRFILAELRREGVdtSHVRVDP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  78 DVRensmIG--FAKLDAKGAATYSFYIDGTTVTVLTADEIVEAIepLATLRYLHVGSVSIAL-DSSGEQILSALKRLKAR 154
Cdd:cd01166    82 GRP----TGlyFLEIGAGGERRVLYYRAGSAASRLTPEDLDEAA--LAGADHLHLSGITLALsESAREALLEALEAAKAR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 155 -PFVFFDPNVRPSvIGNFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLL--ELGASHVVLTKGKDGLQWI 231
Cdd:cd01166   156 gVTVSFDLNYRPK-LWSAEEAREALEELLPYVDIVLPSEEEAEALLGDEDPTDAAERALalALGVKAVVVKLGAEGALVY 234

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1308505515 232 SKSGLdIRVPAIDNPIVDTVGAGDTVSGALLT-YLEEHDI 270
Cdd:cd01166   235 TGGGR-VFVPAYPVEVVDTTGAGDAFAAGFLAgLLEGWDL 273
PRK09434 PRK09434
aminoimidazole riboside kinase; Provisional
 5-270 9.35e-23

aminoimidazole riboside kinase; Provisional


Pssm-ID: 236514 [Multi-domain]  Cd Length: 304  Bit Score: 95.77  E-value: 9.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   5 MGEALIDLIgssnSEGQPCFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDVRENSM 84
Cdd:PRK09434    8 LGDAVVDLI----PEGENRYLKCPGGAPANVAVGIARLGGESGFIGRVGDDPFGRFMQQTLQDEGVDTTYLRLDPAHRTS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  85 IGFAKLDAKGAATYSFYIDGTTVTVLTADEIveaiEPLATLRYLHVGSVSIALDSSGEQILSALKRLK-ARPFVFFDPNV 163
Cdd:PRK09434   84 TVVVDLDDQGERSFTFMVRPSADLFLQPQDL----PPFRQGEWLHLCSIALSAEPSRSTTFEAMRRIKaAGGFVSFDPNL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 164 RPSVIGNFETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISCLL-ELGASHVVLTKGKDG-LQWISKSGLDIRVP 241
Cdd:PRK09434  160 REDLWQDEAELRECLRQALALADVVKLSEEELCFLSGTSQLEDAIYALAdRYPIALLLVTLGAEGvLVHTRGQVQHFPAP 239

                         250       260
                  ....*....|....*....|....*....
gi 1308505515 242 AIDnpIVDTVGAGDTVSGALLTYLEEHDI 270
Cdd:PRK09434  240 SVD--PVDTTGAGDAFVAGLLAGLSQAGL 266
ribokinase_pfkB_like cd00287
ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including ...
 122-265 9.10e-13

ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, 2-dehydro-3-deoxygluconokinase, 1-phosphofructokinase, the minor 6-phosphofructokinase (PfkB), inosine-guanosine kinase, and adenosine kinase. Even though there is a high degree of structural conservation within this superfamily, their multimerization level varies widely, monomeric (e.g. adenosine kinase), dimeric (e.g. ribokinase), and trimeric (e.g THZ kinase).


Pssm-ID: 238177 [Multi-domain]  Cd Length: 196  Bit Score: 65.96  E-value: 9.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 122 LATLRYLHVGSVSIALDSsGEQILSALKRlkARPFVFFDPNVRPSvignfETYRKRVVEVARLASLIKLSHEDLELLF-- 199
Cdd:cd00287    55 LVGADAVVISGLSPAPEA-VLDALEEARR--RGVPVVLDPGPRAV-----RLDGEELEKLLPGVDILTPNEEEAEALTgr 126

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1308505515 200 PDSSVKDGISC---LLELGASHVVLTKGKDGLQWISKSGLDIRVPAIDNPIVDTVGAGDTVSGALLTYL 265
Cdd:cd00287   127 RDLEVKEAAEAaalLLSKGPKVVIVTLGEKGAIVATRGGTEVHVPAFPVKVVDTTGAGDAFLAALAAGL 195
PLN02323 PLN02323
probable fructokinase
 1-265 2.52e-12

probable fructokinase


Pssm-ID: 215183 [Multi-domain]  Cd Length: 330  Bit Score: 66.57  E-value: 2.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515   1 MIAFMGEALIDLI----GSSNSEGqPCFYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKF 76
Cdd:PLN02323   12 LVVCFGEMLIDFVptvsGVSLAEA-PAFKKAPGGAPANVAVGISRLGGSSAFIGKVGDDEFGHMLADILKKNGVNNEGVR 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  77 QDVRENSMIGFAKLDAKGAATYSFYIDGTTVTVLTADEIveAIEPLATLRYLHVGSVSIALDSSGEQILSALKRLK-ARP 155
Cdd:PLN02323   91 FDPGARTALAFVTLRSDGEREFMFYRNPSADMLLRESEL--DLDLIRKAKIFHYGSISLITEPCRSAHLAAMKIAKeAGA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 156 FVFFDPNVR----PSVignfETYRKRVVEVARLASLIKLSHEDLELLFPDSSVKDGISC-LLELGASHVVLTKGKDGLQW 230
Cdd:PLN02323  169 LLSYDPNLRlplwPSA----EAAREGIMSIWDEADIIKVSDEEVEFLTGGDDPDDDTVVkLWHPNLKLLLVTEGEEGCRY 244

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1308505515 231 ISK--SGldiRVPAIDNPIVDTVGAGDTVSGALLTYL 265
Cdd:PLN02323  245 YTKdfKG---RVEGFKVKAVDTTGAGDAFVGGLLSQL 278
D_ribokin_bact TIGR02152
ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose ...
 41-267 7.20e-12

ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars]


Pssm-ID: 274000 [Multi-domain]  Cd Length: 293  Bit Score: 64.93  E-value: 7.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  41 RLDSDVLYIGKLSSDMFGKQMQEYFSAN--NVKMVpkFQDVRENSMIGFAKLDAKGAAtySFYIDGTTVTVLTADEIVEA 118
Cdd:TIGR02152  43 RLGAEVSMIGKVGDDAFGDELLENLKSNgiDTEYV--GTVKDTPTGTAFITVDDTGEN--RIVVVAGANAELTPEDIDAA 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 119 IEPLATLRYlhvgsVSIALDSSGEQILSALKRLKARPF-VFFDPnvRPsVIGNFETyrkrvvEVARLASLIKLSHEDLEL 197
Cdd:TIGR02152 119 EALIAESDI-----VLLQLEIPLETVLEAAKIAKKHGVkVILNP--AP-AIKDLDD------ELLSLVDIITPNETEAEI 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1308505515 198 LFPDS-----SVKDGISCLLELGASHVVLTKGKDGLQWISKSGLDIrVPAIDNPIVDTVGAGDTVSGALLTYLEE 267
Cdd:TIGR02152 185 LTGIEvtdeeDAEKAAEKLLEKGVKNVIITLGSKGALLVSKDESKL-IPAFKVKAVDTTAAGDTFNGAFAVALAE 258
ribokinase cd01174
Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This ...
 41-268 4.94e-11

Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.


Pssm-ID: 238579 [Multi-domain]  Cd Length: 292  Bit Score: 62.18  E-value: 4.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  41 RLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDVRENSMIGFAKLDAKGaatysfyiDGTTVTV------LTADE 114
Cdd:cd01174    48 RLGARVAMIGAVGDDAFGDELLENLREEGIDVSYVEVVVGAPTGTAVITVDESG--------ENRIVVVpgangeLTPAD 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 115 IVEAIEPLATLRYlhvgsVSIALDSSGEQILSALKRLKAR--PFVFfdpNVRPsvignfetYRKRVVEVARLASLIKLSH 192
Cdd:cd01174   120 VDAALELIAAADV-----LLLQLEIPLETVLAALRAARRAgvTVIL---NPAP--------ARPLPAELLALVDILVPNE 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 193 EDLELLF--PDSSVKDGIS---CLLELGASHVVLTKGKDGLQWISKSGLdIRVPAIDNPIVDTVGAGDTVSGALLTYLEE 267
Cdd:cd01174   184 TEAALLTgiEVTDEEDAEKaarLLLAKGVKNVIVTLGAKGALLASGGEV-EHVPAFKVKAVDTTGAGDTFIGALAAALAR 262


                  .
gi 1308505515 268 H 268
Cdd:cd01174   263 G 263
FruK COG1105
1-phosphofructokinase or 6-phosphofructokinase II [Carbohydrate transport and metabolism];
133-267 2.17e-10

1-phosphofructokinase or 6-phosphofructokinase II [Carbohydrate transport and metabolism];


Pssm-ID: 440722 [Multi-domain]  Cd Length: 304  Bit Score: 60.53  E-value: 2.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 133 VSIALDSSGEqilsALKR-LKARPFvffdpnvrpsvignfetyrkrvvevarlasLIKLSHEDLELLF--PDSSVKDGIS 209
Cdd:COG1105   159 AKVVLDTSGE----ALKAaLEAGPD------------------------------LIKPNLEELEELLgrPLETLEDIIA 204

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1308505515 210 C---LLELGASHVVLTKGKDGLQWISKSGLdIRVPAIDNPIVDTVGAGDTVSGALLTYLEE 267
Cdd:COG1105   205 AareLLERGAENVVVSLGADGALLVTEDGV-YRAKPPKVEVVSTVGAGDSMVAGFLAGLAR 264
FruK_PfkB_like cd01164
1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. ...
 125-268 2.10e-09

1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.


Pssm-ID: 238570 [Multi-domain]  Cd Length: 289  Bit Score: 57.54  E-value: 2.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 125 LRYLHVGSVSIALDSSGEQILSAlkrLKARPFvffdpnvrpsvignfetyrkrvvevarlasLIKLSHEDLELLF----- 199
Cdd:cd01164   151 VRLAREKGARVILDTSGEALLAA---LAAKPF------------------------------LIKPNREELEELFgrplg 197

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1308505515 200 PDSSVKDGISCLLELGASHVVLTKGKDGLQWISKSGLdIRVPAIDNPIVDTVGAGDTVSGALLTYLEEH 268
Cdd:cd01164   198 DEEDVIAAARKLIERGAENVLVSLGADGALLVTKDGV-YRASPPKVKVVSTVGAGDSMVAGFVAGLAQG 265
1-PFK TIGR03168
hexose kinase, 1-phosphofructokinase family; This family consists largely of ...
 128-268 2.49e-09

hexose kinase, 1-phosphofructokinase family; This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.


Pssm-ID: 274464 [Multi-domain]  Cd Length: 303  Bit Score: 57.20  E-value: 2.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 128 LHVGSVSIALDSSGEQILSALKrlkARPFvffdpnvrpsvignfetyrkrvvevarlasLIKLSHEDLELLF--PDSSVK 205
Cdd:TIGR03168 153 ARKKGAKVILDTSGEALREALA---AKPF------------------------------LIKPNHEELEELFgrELKTLE 199

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1308505515 206 DGISC---LLELGASHVVLTKGKDGLQWISKSGLdIRVPAIDNPIVDTVGAGDTVSGALLTYLEEH 268
Cdd:TIGR03168 200 EIIEAareLLDRGAENVLVSLGADGALLVTKEGA-LKATPPKVEVVNTVGAGDSMVAGFLAGLARG 264
pfkB TIGR03828
1-phosphofructokinase; This enzyme acts in concert with the fructose-specific ...
 128-262 4.25e-08

1-phosphofructokinase; This enzyme acts in concert with the fructose-specific phosphotransferase system (PTS) which imports fructose as fructose-1-phosphate. The action of 1-phosphofructokinase results in beta-D-fructose-1,6-bisphosphate and is an entry point into glycolysis (GenProp0688).


Pssm-ID: 274804 [Multi-domain]  Cd Length: 304  Bit Score: 53.75  E-value: 4.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 128 LHVGSVSIALDSSGEQILSALKrlkARPFvffdpnvrpsvignfetyrkrvvevarlasLIKLSHEDLELLF-----PDS 202
Cdd:TIGR03828 153 AREKGAKVILDTSGEALRDGLK---AKPF------------------------------LIKPNDEELEELFgrelkTLE 199

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 203 SVKDGISCLLELGASHVVLTKGKDGLQWISKSGLdIRVPAIDNPIVDTVGAGDTVSGALL 262
Cdd:TIGR03828 200 EIIEAARELLDLGAENVLISLGADGALLVTKEGA-LFAQPPKGEVVSTVGAGDSMVAGFL 258
RfaE_like cd01172
RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the ...
 156-261 1.18e-07

RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer membrane of gram-negative bacteria. RfaE consists of two domains, a sugar kinase domain, represented here, and a domain belonging to the cytidylyltransferase superfamily.


Pssm-ID: 238577 [Multi-domain]  Cd Length: 304  Bit Score: 52.18  E-value: 1.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 156 FVFFDPNVRpsvigNFETYRKrvvevarlASLIKLSHEDLEL-----LFPDSSVKDGISCLLE-LGASHVVLTKGKDGLQ 229
Cdd:cd01172   166 PVLVDPKGR-----DYSKYRG--------ATLLTPNEKEAREalgdeINDDDELEAAGEKLLElLNLEALLVTLGEEGMT 232

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1308505515 230 WISKSGLDIRVPAIDNPIVDTVGAGDTVSGAL 261
Cdd:cd01172   233 LFERDGEVQHIPALAKEVYDVTGAGDTVIATL 264
PRK11142 PRK11142
ribokinase; Provisional
 211-309 1.16e-06

ribokinase; Provisional


Pssm-ID: 236858 [Multi-domain]  Cd Length: 306  Bit Score: 49.10  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 211 LLELGASHVVLTKGKDGLqWISKSGLDIRVPAIDNPIVDTVGAGDTVSGALLTYLEEhDIGIGDTVTREQatealefaaA 290
Cdd:PRK11142  210 LHQKGIETVLITLGSRGV-WLSENGEGQRVPGFRVQAVDTIAAGDTFNGALVTALLE-GKPLPEAIRFAH---------A 278

                          90       100
                  ....*....|....*....|.
gi 1308505515 291 AAAVTTSRKGANP--PRRSEI 309
Cdd:PRK11142  279 AAAIAVTRKGAQPsiPWREEI 299
RfaE COG2870
ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell wall/membrane ...
 140-261 1.20e-06

ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442117 [Multi-domain]  Cd Length: 321  Bit Score: 49.42  E-value: 1.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 140 SGEQILSALKRLKAR-PFVFFDPNVRpsvigNFETYRKRVV------EVARLASLIKLSHEDLELLfpdssvkdGISCLL 212
Cdd:COG2870   166 TPELIQALIALARAAgKPVLVDPKGR-----DFSRYRGATLltpnlkEAEAAVGIPIADEEELVAA--------AAELLE 232

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1308505515 213 ELGASHVVLTKGKDGLQWISKSGLDIRVPAIDNPIVDTVGAGDTVSGAL 261
Cdd:COG2870   233 RLGLEALLVTRGEEGMTLFDADGPPHHLPAQAREVFDVTGAGDTVIATL 281
fruK PRK09513
1-phosphofructokinase; Provisional
 125-262 2.73e-06

1-phosphofructokinase; Provisional


Pssm-ID: 181923 [Multi-domain]  Cd Length: 312  Bit Score: 48.15  E-value: 2.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 125 LRYLHVGSVSIALDSSGEQILSALKrlkARPFVFfDPNVRpsvigNFETYRKRvvEVARLASLIKLSHEdlellfpdssv 204
Cdd:PRK09513  154 MTRLRSQCPCIIFDSSREALVAGLK---AAPWLV-KPNRR-----ELEIWAGR--KLPELKDVIEAAHA----------- 211

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1308505515 205 kdgiscLLELGASHVVLTKGKDGLQWISKSGLDIRVPAIDNpIVDTVGAGDTVSGALL 262
Cdd:PRK09513  212 ------LREQGIAHVVISLGAEGALWVNASGEWIAKPPACD-VVSTVGAGDSMVGGLI 262
YegV_kinase_like cd01944
YegV-like sugar kinase. Found only in bacteria, YegV-like kinase is part of the ribokinase ...
 41-265 6.35e-06

YegV-like sugar kinase. Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238919 [Multi-domain]  Cd Length: 289  Bit Score: 47.03  E-value: 6.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  41 RLDSDVLYIGKLSSDMFGKQMQEYFSANNVkmvPKFQDVRENSMIGFAKLDAKGAATYSFyidgttVTVLTADEIVEAiE 120
Cdd:cd01944    47 RLGIPTVNAGPLGNGNWADQIRQAMRDEGI---EILLPPRGGDDGGCLVALVEPDGERSF------ISISGAEQDWST-E 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 121 PLATL-----RYLHVGSVSIALDSSGEQIL-SALKRLKARPFVFFDPNVRPSVIgnfetYRKRVVEVARLASLIKLSHED 194
Cdd:cd01944   117 WFATLtvapyDYVYLSGYTLASENASKVILlEWLEALPAGTTLVFDPGPRISDI-----PDTILQALMAKRPIWSCNREE 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1308505515 195 LELLFP--DSSVKDGISCLLELGASHVVLTKGKDGLQWISKSGLDIRVPAIDNPIVDTVGAGDTVSGALLTYL 265
Cdd:cd01944   192 AAIFAErgDPAAEASALRIYAKTAAPVVVRLGSNGAWIRLPDGNTHIIPGFKVKAVDTIGAGDTHAGGMLAGL 264
ribokinase_group_B cd01945
Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ...
 211-269 1.85e-05

Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .


Pssm-ID: 238920 [Multi-domain]  Cd Length: 284  Bit Score: 45.36  E-value: 1.85e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1308505515 211 LLELGASHVVLTKGKDGLQWISKSGLDIRVPAIDNPIVDTVGAGDTVSGALLTYLEEHD 269
Cdd:cd01945   198 LASLGIPFVAVTLGEAGCLWLERDGELFHVPAFPVEVVDTTGAGDVFHGAFAHALAEGM 256
PTZ00247 PTZ00247
adenosine kinase; Provisional
 44-270 1.51e-04

adenosine kinase; Provisional


Pssm-ID: 240328 [Multi-domain]  Cd Length: 345  Bit Score: 42.71  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  44 SDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDV------------RENSMIgfAKLDAkgAATYSFyidgttvTVLT 111
Cdd:PTZ00247   81 GFVCYVGCVGDDRFAEILKEAAEKDGVEMLFEYTTKaptgtcavlvcgKERSLV--ANLGA--ANHLSA-------EHMQ 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 112 ADEIVEAIEPlATLRYLHVgsvsIALDSSGEQILSALKrlKAR------------PFV---FFDP--NVRPSV---IGNF 171
Cdd:PTZ00247  150 SHAVQEAIKT-AQLYYLEG----FFLTVSPNNVLQVAK--HAResgklfclnlsaPFIsqfFFERllQVLPYVdilFGNE 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 172 EtyrkrvvEVARLASLIKLSHEDLEllfpdsSVKDGISCLLELGASH---VVLTKGKDGLQWISKSGL-DIRVPAID-NP 246
Cdd:PTZ00247  223 E-------EAKTFAKAMKWDTEDLK------EIAARIAMLPKYSGTRprlVVFTQGPEPTLIATKDGVtSVPVPPLDqEK 289

                         250       260
                  ....*....|....*....|....*
gi 1308505515 247 IVDTVGAGDT-VSGALLTYLEEHDI 270
Cdd:PTZ00247  290 IVDTNGAGDAfVGGFLAQYANGKDI 314
PTZ00292 PTZ00292
ribokinase; Provisional
 41-265 2.16e-04

ribokinase; Provisional


Pssm-ID: 185541 [Multi-domain]  Cd Length: 326  Bit Score: 42.42  E-value: 2.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  41 RLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMvpKFQDVRENSMIGFAKL--DAKGAATYSFYIDGTTvtvltaDEIVEA 118
Cdd:PTZ00292   64 KLGAKVAMVGMVGTDGFGSDTIKNFKRNGVNT--SFVSRTENSSTGLAMIfvDTKTGNNEIVIIPGAN------NALTPQ 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 119 IEPLATLRYLHVGSVSIA-LDSSGEQILSALKRLKARPF--VFfdpNVRPSVigNFETYRKrVVEVARLASLIKLSHEDL 195
Cdd:PTZ00292  136 MVDAQTDNIQNICKYLICqNEIPLETTLDALKEAKERGCytVF---NPAPAP--KLAEVEI-IKPFLKYVSLFCVNEVEA 209

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1308505515 196 ELLF-----PDSSVKDGISCLLELGASHVVLTKGKDGLQWISKSGLDIRVPAIDNPIVDTVGAGDTVSGALLTYL 265
Cdd:PTZ00292  210 ALITgmevtDTESAFKASKELQQLGVENVIITLGANGCLIVEKENEPVHVPGKRVKAVDTTGAGDCFVGSMAYFM 284
PLN02341 PLN02341
pfkB-type carbohydrate kinase family protein
 157-277 1.40e-03

pfkB-type carbohydrate kinase family protein


Pssm-ID: 215195 [Multi-domain]  Cd Length: 470  Bit Score: 40.20  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 157 VFFDPNVRPSVIGNFETYRKRVVEVA-RLASLIKLSHEDLELLFPDSSVKDGISCLLE--LGASHVVLTKGKDGLQWISK 233
Cdd:PLN02341  257 VFFDPGPRGKSLLVGTPDERRALEHLlRMSDVLLLTSEEAEALTGIRNPILAGQELLRpgIRTKWVVVKMGSKGSILVTR 336

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1308505515 234 SGLDiRVPAIDNPIVDTVGAGDTVSGAL-LTYLeeHDIGIGDTVT 277
Cdd:PLN02341  337 SSVS-CAPAFKVNVVDTVGCGDSFAAAIaLGYI--HNLPLVNTLT 378
PLN02967 PLN02967
kinase
 24-198 6.48e-03

kinase


Pssm-ID: 215521 [Multi-domain]  Cd Length: 581  Bit Score: 38.10  E-value: 6.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515  24 FYYYSGGCALNAATAAARLDSDVLYIGKLSSDMFGKQMQEYFSANNVKMVPKFQDVRENSMIGFAKLDAKGAATYSFyID 103
Cdd:PLN02967  238 FVRAPGGSAGGVAIALASLGGKVAFMGKLGDDDYGQAMLYYLNVNKVQTRSVCIDGKRATAVSTMKIAKRGRLKTTC-VK 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308505515 104 GTTVTVLTADEIVEAIEPLATLRYLHVGS-VSIALDSSGEQILSALKRLKArpFVFFDPNVRPSVIGNFETYRKRVVEVA 182
Cdd:PLN02967  317 PCAEDSLSKSEINIDVLKEAKMFYFNTHSlLDPTMRSTTLRAIKISKKLGG--VIFYDLNLPLPLWSSSEETKSFIQEAW 394

                         170
                  ....*....|....*.
gi 1308505515 183 RLASLIKLSHEDLELL 198
Cdd:PLN02967  395 NLADIIEVTKQELEFL 410
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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