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Conserved domains on  [gi|1308832079|gb|PKN66210|]
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ABC transporter permease [Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 2-314 6.93e-90

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 270.79  E-value: 6.93e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079   2 RFIWpYLLAALVMIYLSYLLPRLLPGDFVTAMYSSShvtLNAEQEAGLRAYYTNHEGFP----RYLIHLFTLDWGHSYAF 77
Cdd:COG0601     8 RLLQ-AIPVLLGVSTLVFLLLRLLPGDPAAALLGPR---ATPEAIAALRAELGLDQPLLvqylDWLGGLLRGDLGTSFVY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  78 HSPISDLILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAMVLGWFP 157
Cdd:COG0601    84 GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWLP 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 158 ASGAETPYAQFraadrlLDVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALP 237
Cdd:COG0601   164 VSGRVSPWEDF------LDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1308832079 238 PMITRFGLRFAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRVSHG 314
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 2-314 6.93e-90

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 270.79  E-value: 6.93e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079   2 RFIWpYLLAALVMIYLSYLLPRLLPGDFVTAMYSSShvtLNAEQEAGLRAYYTNHEGFP----RYLIHLFTLDWGHSYAF 77
Cdd:COG0601     8 RLLQ-AIPVLLGVSTLVFLLLRLLPGDPAAALLGPR---ATPEAIAALRAELGLDQPLLvqylDWLGGLLRGDLGTSFVY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  78 HSPISDLILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAMVLGWFP 157
Cdd:COG0601    84 GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWLP 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 158 ASGAETPYAQFraadrlLDVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALP 237
Cdd:COG0601   164 VSGRVSPWEDF------LDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1308832079 238 PMITRFGLRFAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRVSHG 314
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 12-311 1.20e-41

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 146.40  E-value: 1.20e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  12 LVMIYLSYLLPRLLPGD---FVTAMYSSSHVTLNAEQEAGLRAyyTNHEGFPRYLIHLFTLDWGHSYAFHSPISDLILSA 88
Cdd:PRK15081   17 LIVAVLVFLFVHLLPGDparLAAGPEADAQVVALVRQQLGLDQ--PLPHQFWHYISNALQGDFGTSMVSRRPVSEEIASR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  89 LPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKasVGCMTMLEGV--PEIATGVVLLLVFAMVLGWFPASGAetpya 166
Cdd:PRK15081   95 FMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDR--LGMTLAVSGIsfPAFALGMLLMQVFSVELGWLPTVGA----- 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 167 qfraadrllDVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLR 246
Cdd:PRK15081  168 ---------DSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQ 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1308832079 247 FAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRV 311
Cdd:PRK15081  239 FGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAI 303
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 107-313 3.48e-21

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 88.90  E-value: 3.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 107 GFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIAtgVVLLLVFAMVLGWFpasgaetpyaqfraadrlldvaHHLVLPFC 186
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFV--LAILLVVIAILSIL----------------------GHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 187 TLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLRFAFMVTGALVVETIYAYPGL 266
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1308832079 267 GTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRVSH 313
Cdd:pfam00528 137 GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 89-296 1.00e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 62.68  E-value: 1.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  89 LPWTLLLVGGAHVISMIMGFIAGVeAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAMVLGWfpasgaetpyaqf 168
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGI-ILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 169 raadrllDVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLRFA 248
Cdd:cd06261    67 -------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFA 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1308832079 249 FMVTGALVVETI--YAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLII 296
Cdd:cd06261   140 RALGEFALVSFLggGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 2-314 6.93e-90

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 270.79  E-value: 6.93e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079   2 RFIWpYLLAALVMIYLSYLLPRLLPGDFVTAMYSSShvtLNAEQEAGLRAYYTNHEGFP----RYLIHLFTLDWGHSYAF 77
Cdd:COG0601     8 RLLQ-AIPVLLGVSTLVFLLLRLLPGDPAAALLGPR---ATPEAIAALRAELGLDQPLLvqylDWLGGLLRGDLGTSFVY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  78 HSPISDLILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAMVLGWFP 157
Cdd:COG0601    84 GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWLP 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 158 ASGAETPYAQFraadrlLDVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALP 237
Cdd:COG0601   164 VSGRVSPWEDF------LDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1308832079 238 PMITRFGLRFAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRVSHG 314
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 12-311 1.20e-41

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 146.40  E-value: 1.20e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  12 LVMIYLSYLLPRLLPGD---FVTAMYSSSHVTLNAEQEAGLRAyyTNHEGFPRYLIHLFTLDWGHSYAFHSPISDLILSA 88
Cdd:PRK15081   17 LIVAVLVFLFVHLLPGDparLAAGPEADAQVVALVRQQLGLDQ--PLPHQFWHYISNALQGDFGTSMVSRRPVSEEIASR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  89 LPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKasVGCMTMLEGV--PEIATGVVLLLVFAMVLGWFPASGAetpya 166
Cdd:PRK15081   95 FMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDR--LGMTLAVSGIsfPAFALGMLLMQVFSVELGWLPTVGA----- 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 167 qfraadrllDVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLR 246
Cdd:PRK15081  168 ---------DSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQ 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1308832079 247 FAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRV 311
Cdd:PRK15081  239 FGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAI 303
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-311 6.23e-35

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 128.65  E-value: 6.23e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079   1 MRFIWPYLLAA----LVMIYLSYLLPRLLPGDFVTamyssSHVTLNAEQEAGLRA-YYTNHEGFPRYLIHLFTL---DWG 72
Cdd:PRK09471    2 LKFILRRCLEAiptlFILITISFFMMRLAPGSPFT-----GERTLPPEVMANIEAkYHLNDPIMTQYFSYLKQLahgDFG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  73 HSYAFHS-PISDLILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAM 151
Cdd:PRK09471   77 PSFKYKDySVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 152 VLGWFPASGAETPYAQFraadrlldvahhLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHA 231
Cdd:PRK09471  157 TLHWLPGGGWNGGALKF------------MILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHA 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 232 ARNALPPMITRFGLRFAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRV 311
Cdd:PRK09471  225 LKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKI 304
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
17-314 7.91e-32

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 121.07  E-value: 7.91e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  17 LSYLLPRLLPGDFVTAMysSSHVTLNAEQEAGLRAYY----TNHEGFPRYLIHLFTLDWGHSYAFHSPISDLILSALPWT 92
Cdd:PRK10914   22 LTFAFVHMIPGDPVMIM--AGERGISPERHAQLLAELgldkPMWQQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKAT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  93 LLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAMVLGWFPASGA---------ET 163
Cdd:PRK10914  100 LELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRvsdmvflddSN 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 164 PYAQFRAADRLL--------DVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNA 235
Cdd:PRK10914  180 PLTGFMLIDTAIwgedgnfiDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNA 259

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1308832079 236 LPPMITRFGLRFAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRVSHG 314
Cdd:PRK10914  260 MLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHK 338
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 6-314 7.93e-32

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 120.57  E-value: 7.93e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079   6 PYLLAALVMIYLsylLPRLLPGDFVTAMYSSSHVTLNAEQEAGLRAYY----TNHEGFPRYLIHLFTLDWGHSYAFHSPI 81
Cdd:PRK10352   14 PMLLAASVIIFL---MLRLGTGDPALDYLRLSNLPPTPEMLASTRTMLgldqPLYVQYGTWLWKALHLDFGISFATQRPV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  82 SDLILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAMVLGWFPASGA 161
Cdd:PRK10352   91 LDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYLQWLPAMGY 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 162 ETpyaqfraadrlldvAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMIT 241
Cdd:PRK10352  171 GG--------------WQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMIT 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1308832079 242 RFGLRFAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRVSHG 314
Cdd:PRK10352  237 AVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRH 309
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 41-311 6.73e-29

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 113.74  E-value: 6.73e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  41 LNAEQEAGLRAYYtnheGF-----PRYLIHL---FTLDWGHSYAFHSPISDLILSALP-------WTLLLVggaHVISMI 105
Cdd:COG4174    78 LDPEFIAELEKQY----GFdkpahERFLLMLknyLRFDFGESYFRDISVIDLILEKLPvsislglWSTLLT---YLISIP 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 106 MGfiagVEAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFA--MVLGWFPASGAETP-YAQFRAADRLLDVAHHLV 182
Cdd:COG4174   151 LG----IRKAVRDGSRFDVWTSTVIIVGYAIPGFLFAILLIVLFAggSYFDWFPLRGLTSDnWDQLSWWGKILDYLWHLT 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 183 LPfctlIAAYLPGNF----LLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLRF--AFMvTGALV 256
Cdd:COG4174   227 LP----VTAMVIGGFatltLLTKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIAGFPAAFigAFF-TGSLL 301

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1308832079 257 VETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRV 311
Cdd:COG4174   302 IETIFSLDGLGLLGFEAVVNRDYPVVFGTLYIFTLIGLVLKLISDLTYVLVDPRI 356
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 107-313 3.48e-21

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 88.90  E-value: 3.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 107 GFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIAtgVVLLLVFAMVLGWFpasgaetpyaqfraadrlldvaHHLVLPFC 186
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFV--LAILLVVIAILSIL----------------------GHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 187 TLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLRFAFMVTGALVVETIYAYPGL 266
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1308832079 267 GTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPRVSH 313
Cdd:pfam00528 137 GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
PRK15110 PRK15110
peptide ABC transporter permease SapB;
62-313 6.95e-21

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 90.90  E-value: 6.95e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  62 YLIHLFTLDWGHSYAFHSPISDLILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEGVPEIAT 141
Cdd:PRK15110   47 WFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWL 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 142 GVVLLLVFAMVLGWFPASG---------------------AETPYAQfraaDRLLDVAHHLVLPFCTLIAAYLPGNFLLT 200
Cdd:PRK15110  127 ALLLTLFFSLTLGWLPVSGrfdllyevkpvtgfalidawlSDSPWRD----EMIMSAIRHMILPVITLAVAPTTEVIRLM 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 201 RGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLRFAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLP 280
Cdd:PRK15110  203 RISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYA 282

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1308832079 281 LIQSIVLISSLMVLIINLaLEWIYGRMDPRVSH 313
Cdd:PRK15110  283 AISAGVMVVGSLVIIVNV-LSDILGAMANPLKH 314
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 56-311 1.82e-19

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 87.49  E-value: 1.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  56 HEGFPRYLIHLFTLDWGHSYAFHSPISDLILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRRGGGVEKASVGCMTMLEG 135
Cdd:PRK15133  100 HERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRFDVWSSAFIIIGYA 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 136 VPEIATGVVLLLVFA--MVLGWFPASGAETPyaQFRAA---DRLLDVAHHLVLPfctlIAAYLPGNF----LLTRGSMVM 206
Cdd:PRK15133  180 IPAFLFAILLIVFFAggSYFDLFPLRGLVSA--NFDSLpwyQKITDYLWHITLP----VLATVIGGFaaltMLTKNSFLD 253

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 207 LLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLRFAFM-VTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSI 285
Cdd:PRK15133  254 EIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMfFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGT 333

                         250       260
                  ....*....|....*....|....*.
gi 1308832079 286 VLISSLMVLIINLALEWIYGRMDPRV 311
Cdd:PRK15133  334 LYIFTLIGLLLNIVSDISYTLVDPRI 359
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 89-296 1.00e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 62.68  E-value: 1.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  89 LPWTLLLVGGAHVISMIMGFIAGVeAAWRRGGGVEKASVGCMTMLEGVPEIATGVVLLLVFAMVLGWfpasgaetpyaqf 168
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGI-ILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 169 raadrllDVAHHLVLPFCTLIAAYLPGNFLLTRGSMVMLLKEQFVETARAKGLPPVRIRYAHAARNALPPMITRFGLRFA 248
Cdd:cd06261    67 -------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFA 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1308832079 249 FMVTGALVVETI--YAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLII 296
Cdd:cd06261   140 RALGEFALVSFLggGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 85-251 1.68e-05

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 45.49  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079  85 ILSALPWTLLLVGGAHVISMIMGFIAGVEAAWRrGGGVEKASVGCMTMLEGVPeiatGVVLLLVFAMVLGwfpaSGaetp 164
Cdd:COG1173    74 LLYGARISLLVGLLAVLIALVIGVLLGLLAGYF-GGWVDAVLMRLVDVLLAFP----SLLLAIALVAVLG----PG---- 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308832079 165 yaqfraadrlldvahhLVLPFCTLIAAYLPGNFLLTRGsMVMLLKEQ-FVETARAKGLPPVRIRYAHAARNALPPMITRF 243
Cdd:COG1173   141 ----------------LLNVILALGLTGWPGYARLVRA-QVLSLREReYVEAARALGASPLRIIFRHILPNVLPPLIVQA 203


                  ....*...
gi 1308832079 244 GLRFAFMV 251
Cdd:COG1173   204 TLGIASAI 211
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 235-310 7.03e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 37.43  E-value: 7.03e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1308832079 235 ALPPMITrfGLR--FAFMVTGALVVETIYAYPGLGTLLFNAVSMRDLPLIQSIVLISSLMVLIINLALEWIYGRMDPR 310
Cdd:COG0600   178 ALPYIFT--GLRiaLGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLERRLLRW 253
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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