View
Concise Results
Standard Results
Full Results
RecName: Full=Solute carrier family 12 member 1; AltName: Full=Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; AltName: Full=Kidney-specific Na-K-Cl symporter
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
104-1099
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1506.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 104 NT M DAVP K IE Y YRN TGSIS GPK V NRPSL L E I H EQ L A K N V AVTPSS AD RVA NG D G IPGD E Q AE N ---- KE DDQ AG V VKFGW 179
Cdd:TIGR00930 1 NT V DAVP R IE H YRN SEGQG GPK R NRPSL E E L H DL L D K V V SLLGPL AD YTN NG Q G MKEH E E AE D aegt KE KPP AG A VKFGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 180 V K GVLV R C M LNIWGV M LF I RLSWIVG E AGIGL GV LIILL STM VT S ITGLS T SAIATNG F V R GGGAYYLISRSLGPEFGGS 259
Cdd:TIGR00930 81 V M GVLV P C L LNIWGV I LF L RLSWIVG Q AGIGL SL LIILL CCC VT T ITGLS M SAIATNG V V K GGGAYYLISRSLGPEFGGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 260 IGLIFAFANAVAVAMYVVGFAETV V DLL K E SD S - M MVDP T NDIRI I G SI TVV I LLGIS V AGMEWE A KAQV IL LVI L L IA I 338
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETV L DLL R E NG S k I MVDP I NDIRI Y G TV TVV V LLGIS F AGMEWE N KAQV LF LVI V L LS I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 339 A N F F I GT V IP SNN e K KSR GFF NYQAS IF A ENF G P RFTKG EG - FFS V F A IFFP AA TGILAGANISGDL E DPQ D AIP R GT M L 417
Cdd:TIGR00930 241 L N I F V GT I IP AFD - K PAK GFF GLGNE IF S ENF I P GIPGP EG g FFS L F G IFFP SV TGILAGANISGDL K DPQ K AIP K GT L L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 418 AI FI TTV A YLG VAICV GACVVRDATG NM NDT IIS gmn CNG SAAC glgyd FS R C R H EP C Q YGLMNN F QVMS M VS G F G PLIT 497
Cdd:TIGR00930 320 AI LT TTV V YLG SVVLF GACVVRDATG DK NDT LVT --- NCT SAAC ----- FS E C A H NT C S YGLMNN L QVMS L VS P F P PLIT 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 498 AGIFSATLSSALASLVSAP KV FQALCKDNIY KA LQFF A KGYGKN N EPLR G Y I LT FL IA MA FILIAELNTIAPIISNFFLA 577
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAP RL FQALCKDNIY PF LQFF G KGYGKN G EPLR A Y L LT AF IA EG FILIAELNTIAPIISNFFLA 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 578 SYALINFSCFHAS YAK SPGWRP AYGI Y NM W V SL F GA V LCCA V MF V I N WWAA VITY VI EF FLY V YVT C KKPDVNWGSSTQA 657
Cdd:TIGR00930 472 SYALINFSCFHAS LLR SPGWRP RFKY Y HW W L SL L GA S LCCA I MF L I S WWAA LVAM VI AL FLY K YVT Y KKPDVNWGSSTQA 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 658 LSY VS AL DNA L E L TT VEDHVKN F RPQC I VLTG G P MT RPALLD ITHA FTK NS GL C IC CE V FV GPR KL CVKE MNSGM AK K Q A 737
Cdd:TIGR00930 552 LSY SL AL YSL L R L EE VEDHVKN W RPQC L VLTG P P VC RPALLD FASQ FTK GK GL M IC GS V IQ GPR LE CVKE AQAAE AK I Q T 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 738 WL I KNK I KAFYA A V A AD CF R D GVR S L L QASGLGRMKPNTLV I GYKK N WR K A PLTEI E N Y V GIIHDAFD FEIG VV I VR I S Q 817
Cdd:TIGR00930 632 WL E KNK V KAFYA V V V AD DL R E GVR H L I QASGLGRMKPNTLV M GYKK D WR Q A EPRAW E T Y I GIIHDAFD AHLA VV V VR N S E 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 818 G FD IS q VLQVQEELE rleqerlaleatikd N E C E E E S ggirglfkkagklnitkt TPKK DG S I N T SQS MH vgefnqkl V E 897
Cdd:TIGR00930 712 G LP IS - VLQVQEELE --------------- N D C S E D S ------------------ IELN DG K I S T QPD MH -------- L E 749
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 898 ASTQF K KKQ E KGTIDVWWL F DDGGLTLL I PY I LT LR K K WK D CK L RI Y VG G - K IN R I E E EK IV MA S LL S KFRI KFAD I HII 976
Cdd:TIGR00930 750 ASTQF Q KKQ G KGTIDVWWL V DDGGLTLL L PY L LT TK K V WK K CK I RI F VG A q K DD R S E Q EK KD MA T LL Y KFRI DAEV I VVL 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 977 G DIN IR P NK ES WKV FEEMI E P Y RLH ESC KD LTTAE - K LKRET PWKITDAEL EAVKE KSYRQVRLNELL Q E H SR A A N L I VL 1055
Cdd:TIGR00930 830 M DIN AK P QT ES MEA FEEMI R P F RLH KTE KD REAKD p K MTWTK PWKITDAEL QSNVR KSYRQVRLNELL L E Y SR D A A L V VL 909
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 212276464 1056 SLPV A RKGSI S D L LYMAWLE I L TKN LPPVLLVRGNH K NVLTFYS 1099
Cdd:TIGR00930 910 SLPV P RKGSI P D E LYMAWLE V L SED LPPVLLVRGNH R NVLTFYS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
104-1099
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1506.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 104 NT M DAVP K IE Y YRN TGSIS GPK V NRPSL L E I H EQ L A K N V AVTPSS AD RVA NG D G IPGD E Q AE N ---- KE DDQ AG V VKFGW 179
Cdd:TIGR00930 1 NT V DAVP R IE H YRN SEGQG GPK R NRPSL E E L H DL L D K V V SLLGPL AD YTN NG Q G MKEH E E AE D aegt KE KPP AG A VKFGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 180 V K GVLV R C M LNIWGV M LF I RLSWIVG E AGIGL GV LIILL STM VT S ITGLS T SAIATNG F V R GGGAYYLISRSLGPEFGGS 259
Cdd:TIGR00930 81 V M GVLV P C L LNIWGV I LF L RLSWIVG Q AGIGL SL LIILL CCC VT T ITGLS M SAIATNG V V K GGGAYYLISRSLGPEFGGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 260 IGLIFAFANAVAVAMYVVGFAETV V DLL K E SD S - M MVDP T NDIRI I G SI TVV I LLGIS V AGMEWE A KAQV IL LVI L L IA I 338
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETV L DLL R E NG S k I MVDP I NDIRI Y G TV TVV V LLGIS F AGMEWE N KAQV LF LVI V L LS I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 339 A N F F I GT V IP SNN e K KSR GFF NYQAS IF A ENF G P RFTKG EG - FFS V F A IFFP AA TGILAGANISGDL E DPQ D AIP R GT M L 417
Cdd:TIGR00930 241 L N I F V GT I IP AFD - K PAK GFF GLGNE IF S ENF I P GIPGP EG g FFS L F G IFFP SV TGILAGANISGDL K DPQ K AIP K GT L L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 418 AI FI TTV A YLG VAICV GACVVRDATG NM NDT IIS gmn CNG SAAC glgyd FS R C R H EP C Q YGLMNN F QVMS M VS G F G PLIT 497
Cdd:TIGR00930 320 AI LT TTV V YLG SVVLF GACVVRDATG DK NDT LVT --- NCT SAAC ----- FS E C A H NT C S YGLMNN L QVMS L VS P F P PLIT 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 498 AGIFSATLSSALASLVSAP KV FQALCKDNIY KA LQFF A KGYGKN N EPLR G Y I LT FL IA MA FILIAELNTIAPIISNFFLA 577
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAP RL FQALCKDNIY PF LQFF G KGYGKN G EPLR A Y L LT AF IA EG FILIAELNTIAPIISNFFLA 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 578 SYALINFSCFHAS YAK SPGWRP AYGI Y NM W V SL F GA V LCCA V MF V I N WWAA VITY VI EF FLY V YVT C KKPDVNWGSSTQA 657
Cdd:TIGR00930 472 SYALINFSCFHAS LLR SPGWRP RFKY Y HW W L SL L GA S LCCA I MF L I S WWAA LVAM VI AL FLY K YVT Y KKPDVNWGSSTQA 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 658 LSY VS AL DNA L E L TT VEDHVKN F RPQC I VLTG G P MT RPALLD ITHA FTK NS GL C IC CE V FV GPR KL CVKE MNSGM AK K Q A 737
Cdd:TIGR00930 552 LSY SL AL YSL L R L EE VEDHVKN W RPQC L VLTG P P VC RPALLD FASQ FTK GK GL M IC GS V IQ GPR LE CVKE AQAAE AK I Q T 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 738 WL I KNK I KAFYA A V A AD CF R D GVR S L L QASGLGRMKPNTLV I GYKK N WR K A PLTEI E N Y V GIIHDAFD FEIG VV I VR I S Q 817
Cdd:TIGR00930 632 WL E KNK V KAFYA V V V AD DL R E GVR H L I QASGLGRMKPNTLV M GYKK D WR Q A EPRAW E T Y I GIIHDAFD AHLA VV V VR N S E 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 818 G FD IS q VLQVQEELE rleqerlaleatikd N E C E E E S ggirglfkkagklnitkt TPKK DG S I N T SQS MH vgefnqkl V E 897
Cdd:TIGR00930 712 G LP IS - VLQVQEELE --------------- N D C S E D S ------------------ IELN DG K I S T QPD MH -------- L E 749
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 898 ASTQF K KKQ E KGTIDVWWL F DDGGLTLL I PY I LT LR K K WK D CK L RI Y VG G - K IN R I E E EK IV MA S LL S KFRI KFAD I HII 976
Cdd:TIGR00930 750 ASTQF Q KKQ G KGTIDVWWL V DDGGLTLL L PY L LT TK K V WK K CK I RI F VG A q K DD R S E Q EK KD MA T LL Y KFRI DAEV I VVL 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 977 G DIN IR P NK ES WKV FEEMI E P Y RLH ESC KD LTTAE - K LKRET PWKITDAEL EAVKE KSYRQVRLNELL Q E H SR A A N L I VL 1055
Cdd:TIGR00930 830 M DIN AK P QT ES MEA FEEMI R P F RLH KTE KD REAKD p K MTWTK PWKITDAEL QSNVR KSYRQVRLNELL L E Y SR D A A L V VL 909
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 212276464 1056 SLPV A RKGSI S D L LYMAWLE I L TKN LPPVLLVRGNH K NVLTFYS 1099
Cdd:TIGR00930 910 SLPV P RKGSI P D E LYMAWLE V L SED LPPVLLVRGNH R NVLTFYS 953
SLC12
pfam03522 Solute carrier family 12;
694-1099
0e+00
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 596.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 694 RPAL L D IT H AF TKN SG L C IC CE V FV G PRKLCVKEMN sg MA K KQA WL I K N KIKAFYA A V AA D CF R D G VRS LLQASGLG RM K 773
Cdd:pfam03522 1 RPAL V D FA H LI TKN VS L M IC GH V VK G RLSQKLRSEL -- QK K AYR WL R K R KIKAFYA L V DG D NL R E G AQA LLQASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 774 PN T L VI GYK KN WR KAPLT E I E N Y VGI IHDAFD FEIG V V I V R ISQ G F D I S QV LQ V Q EEL E RLEQERLALEATIKDN E CEEE 853
Cdd:pfam03522 79 PN I L LM GYK SD WR TCDKE E L E E Y FNV IHDAFD LQYA V A I L R LPE G L D V S HL LQ D Q DTE E LGLGDETNSSYAEQSS E EQST 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 854 S GGIRGLF K KAGK --------- LNITKTT P KKDG S INTSQSMHVGEF -------- NQKLVEAS TQF K KKQ E KGTIDVWWL 916
Cdd:pfam03522 159 S NSKQDDD K SKLS kkdsnlsls PDKSTKN P SGKD S SKSDKLKKKSPS iilrtasn EKEILNNI TQF Q KKQ K KGTIDVWWL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 917 F DDGGLTLL I PYIL TL R K KW K DCKLR IYVG G - KINRI EEE KIV MASLLSKFRI KFA D IHI I G DI NIR P N KE SW K V F E E M I 995
Cdd:pfam03522 239 Y DDGGLTLL L PYIL ST R S KW S DCKLR VFAL G n RKDEL EEE QRN MASLLSKFRI DYS D LTV I P DI TKK P K KE TK K F F D E L I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 996 EP Y RLHE SC K DL ttaeklkr E TPW KITD A ELEA V KEK SY RQ V RL N ELL Q EHS RA ANLIV LS LP VA RKG SI S DL LYMAWLE 1075
Cdd:pfam03522 319 EP F RLHE DD K EE -------- E SAE KITD S ELEA L KEK TN RQ L RL R ELL L EHS SD ANLIV MT LP MP RKG TV S AP LYMAWLE 390
410 420
....*....|....*....|....
gi 212276464 1076 I LTK N LPP V LLVRGN HKN VLTFYS 1099
Cdd:pfam03522 391 T LTK D LPP F LLVRGN QTS VLTFYS 414
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
190-649
2.36e-37
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 146.58
E-value: 2.36e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 190 N I W G VML F IRLSWIV G E AG i GLGV L II L LSTMVTSITG LS TSAI A TN g F V R G GGAY YLIS R S LGP EF G GSI G LIFAFANA 269
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG - PAAI L AW L IAGLLALLVA LS YAEL A SA - F P R A GGAY TYAR R A LGP LL G FLA G WALLLSYV 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 270 V AVA MYV V G F AETVVD L L kesdsmmvd P TNDIRI I GSITVVI L LGISVA G MEWE AK AQV IL L V IL L IAIAN F FIG tvips 349
Cdd:COG0531 103 L AVA AVA V A F GGYLSS L F --------- P AGGSVL I ALVLILL L TLLNLR G VKES AK VNN IL T V LK L LVLLL F IVV ----- 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 350 nnekksr G F F NYQASI F A e N F G P RFTKGE G FFSVF A IF F P A A TG IL A G AN ISGDLED P QDA IPR GTM L AIF I TT V A Y LG V 429
Cdd:COG0531 169 ------- G L F AFDPAN F T - P F L P AGGGLS G VLAAL A LA F F A F TG FE A I AN LAEEAKN P KRN IPR AII L SLL I VG V L Y IL V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 430 AICVGAC V VR D ATGNMNDTI isgmncngsaacglgydfsrcrhepcqyglmnn FQVMSM V S G -- FGP LI TA G IFSAT L SS 507
Cdd:COG0531 241 SLALTGV V PY D ELAASGAPL --------------------------------- ADAAEA V F G pw GAI LI AL G ALLSL L GA 287
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 508 AL AS LVS A PKVFQ A LCK D NI yk ALQF FAK GYGKNNE P LRGYI LT FL IA MAFI L I -- A ELNTI A PII S NFF L AS Y A L INFS 585
Cdd:COG0531 288 LN AS ILG A SRLLY A MAR D GL -- LPKV FAK VHPRFGT P VNAIL LT GV IA LLLL L L ga A SFTAL A SLA S VGV L LA Y L L VALA 365
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 212276464 586 CFHASY a KS P GWRPAYGIYNMWVSLF G AV LC CAVMFVINWW A --- AVITYV I EFF LY VYVTCKK P DV 649
Cdd:COG0531 366 VIVLRR - RR P DLPRPFRVPLPLIPIL G IL LC LFLLYLLGPG A lli GLVLLA I GLL LY LLYRRRH P KL 431
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
104-1099
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1506.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 104 NT M DAVP K IE Y YRN TGSIS GPK V NRPSL L E I H EQ L A K N V AVTPSS AD RVA NG D G IPGD E Q AE N ---- KE DDQ AG V VKFGW 179
Cdd:TIGR00930 1 NT V DAVP R IE H YRN SEGQG GPK R NRPSL E E L H DL L D K V V SLLGPL AD YTN NG Q G MKEH E E AE D aegt KE KPP AG A VKFGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 180 V K GVLV R C M LNIWGV M LF I RLSWIVG E AGIGL GV LIILL STM VT S ITGLS T SAIATNG F V R GGGAYYLISRSLGPEFGGS 259
Cdd:TIGR00930 81 V M GVLV P C L LNIWGV I LF L RLSWIVG Q AGIGL SL LIILL CCC VT T ITGLS M SAIATNG V V K GGGAYYLISRSLGPEFGGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 260 IGLIFAFANAVAVAMYVVGFAETV V DLL K E SD S - M MVDP T NDIRI I G SI TVV I LLGIS V AGMEWE A KAQV IL LVI L L IA I 338
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETV L DLL R E NG S k I MVDP I NDIRI Y G TV TVV V LLGIS F AGMEWE N KAQV LF LVI V L LS I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 339 A N F F I GT V IP SNN e K KSR GFF NYQAS IF A ENF G P RFTKG EG - FFS V F A IFFP AA TGILAGANISGDL E DPQ D AIP R GT M L 417
Cdd:TIGR00930 241 L N I F V GT I IP AFD - K PAK GFF GLGNE IF S ENF I P GIPGP EG g FFS L F G IFFP SV TGILAGANISGDL K DPQ K AIP K GT L L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 418 AI FI TTV A YLG VAICV GACVVRDATG NM NDT IIS gmn CNG SAAC glgyd FS R C R H EP C Q YGLMNN F QVMS M VS G F G PLIT 497
Cdd:TIGR00930 320 AI LT TTV V YLG SVVLF GACVVRDATG DK NDT LVT --- NCT SAAC ----- FS E C A H NT C S YGLMNN L QVMS L VS P F P PLIT 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 498 AGIFSATLSSALASLVSAP KV FQALCKDNIY KA LQFF A KGYGKN N EPLR G Y I LT FL IA MA FILIAELNTIAPIISNFFLA 577
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAP RL FQALCKDNIY PF LQFF G KGYGKN G EPLR A Y L LT AF IA EG FILIAELNTIAPIISNFFLA 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 578 SYALINFSCFHAS YAK SPGWRP AYGI Y NM W V SL F GA V LCCA V MF V I N WWAA VITY VI EF FLY V YVT C KKPDVNWGSSTQA 657
Cdd:TIGR00930 472 SYALINFSCFHAS LLR SPGWRP RFKY Y HW W L SL L GA S LCCA I MF L I S WWAA LVAM VI AL FLY K YVT Y KKPDVNWGSSTQA 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 658 LSY VS AL DNA L E L TT VEDHVKN F RPQC I VLTG G P MT RPALLD ITHA FTK NS GL C IC CE V FV GPR KL CVKE MNSGM AK K Q A 737
Cdd:TIGR00930 552 LSY SL AL YSL L R L EE VEDHVKN W RPQC L VLTG P P VC RPALLD FASQ FTK GK GL M IC GS V IQ GPR LE CVKE AQAAE AK I Q T 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 738 WL I KNK I KAFYA A V A AD CF R D GVR S L L QASGLGRMKPNTLV I GYKK N WR K A PLTEI E N Y V GIIHDAFD FEIG VV I VR I S Q 817
Cdd:TIGR00930 632 WL E KNK V KAFYA V V V AD DL R E GVR H L I QASGLGRMKPNTLV M GYKK D WR Q A EPRAW E T Y I GIIHDAFD AHLA VV V VR N S E 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 818 G FD IS q VLQVQEELE rleqerlaleatikd N E C E E E S ggirglfkkagklnitkt TPKK DG S I N T SQS MH vgefnqkl V E 897
Cdd:TIGR00930 712 G LP IS - VLQVQEELE --------------- N D C S E D S ------------------ IELN DG K I S T QPD MH -------- L E 749
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 898 ASTQF K KKQ E KGTIDVWWL F DDGGLTLL I PY I LT LR K K WK D CK L RI Y VG G - K IN R I E E EK IV MA S LL S KFRI KFAD I HII 976
Cdd:TIGR00930 750 ASTQF Q KKQ G KGTIDVWWL V DDGGLTLL L PY L LT TK K V WK K CK I RI F VG A q K DD R S E Q EK KD MA T LL Y KFRI DAEV I VVL 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 977 G DIN IR P NK ES WKV FEEMI E P Y RLH ESC KD LTTAE - K LKRET PWKITDAEL EAVKE KSYRQVRLNELL Q E H SR A A N L I VL 1055
Cdd:TIGR00930 830 M DIN AK P QT ES MEA FEEMI R P F RLH KTE KD REAKD p K MTWTK PWKITDAEL QSNVR KSYRQVRLNELL L E Y SR D A A L V VL 909
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 212276464 1056 SLPV A RKGSI S D L LYMAWLE I L TKN LPPVLLVRGNH K NVLTFYS 1099
Cdd:TIGR00930 910 SLPV P RKGSI P D E LYMAWLE V L SED LPPVLLVRGNH R NVLTFYS 953
SLC12
pfam03522 Solute carrier family 12;
694-1099
0e+00
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 596.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 694 RPAL L D IT H AF TKN SG L C IC CE V FV G PRKLCVKEMN sg MA K KQA WL I K N KIKAFYA A V AA D CF R D G VRS LLQASGLG RM K 773
Cdd:pfam03522 1 RPAL V D FA H LI TKN VS L M IC GH V VK G RLSQKLRSEL -- QK K AYR WL R K R KIKAFYA L V DG D NL R E G AQA LLQASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 774 PN T L VI GYK KN WR KAPLT E I E N Y VGI IHDAFD FEIG V V I V R ISQ G F D I S QV LQ V Q EEL E RLEQERLALEATIKDN E CEEE 853
Cdd:pfam03522 79 PN I L LM GYK SD WR TCDKE E L E E Y FNV IHDAFD LQYA V A I L R LPE G L D V S HL LQ D Q DTE E LGLGDETNSSYAEQSS E EQST 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 854 S GGIRGLF K KAGK --------- LNITKTT P KKDG S INTSQSMHVGEF -------- NQKLVEAS TQF K KKQ E KGTIDVWWL 916
Cdd:pfam03522 159 S NSKQDDD K SKLS kkdsnlsls PDKSTKN P SGKD S SKSDKLKKKSPS iilrtasn EKEILNNI TQF Q KKQ K KGTIDVWWL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 917 F DDGGLTLL I PYIL TL R K KW K DCKLR IYVG G - KINRI EEE KIV MASLLSKFRI KFA D IHI I G DI NIR P N KE SW K V F E E M I 995
Cdd:pfam03522 239 Y DDGGLTLL L PYIL ST R S KW S DCKLR VFAL G n RKDEL EEE QRN MASLLSKFRI DYS D LTV I P DI TKK P K KE TK K F F D E L I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 996 EP Y RLHE SC K DL ttaeklkr E TPW KITD A ELEA V KEK SY RQ V RL N ELL Q EHS RA ANLIV LS LP VA RKG SI S DL LYMAWLE 1075
Cdd:pfam03522 319 EP F RLHE DD K EE -------- E SAE KITD S ELEA L KEK TN RQ L RL R ELL L EHS SD ANLIV MT LP MP RKG TV S AP LYMAWLE 390
410 420
....*....|....*....|....
gi 212276464 1076 I LTK N LPP V LLVRGN HKN VLTFYS 1099
Cdd:pfam03522 391 T LTK D LPP F LLVRGN QTS VLTFYS 414
AA_permease
pfam00324 Amino acid permease;
182-685
2.59e-126
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 393.99
E-value: 2.59e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 182 G V LVRCMLNIW G VM LF IRLSWIV G E AG IGLGV L II L L S TM V TSITG LS TSA I A TNG F V r G GG A Y YLI SR S LGP EF G GSI G 261
Cdd:pfam00324 1 H V QMIALGGVI G TG LF VGSGSVL G Q AG PAGAL L GY L I S GV V IFLVM LS LGE I S TNG P V - S GG F Y TYA SR F LGP SL G FAT G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 262 L ------ I FAF A NAVAV A MYVVG F A E T V V D LLKES dsmmvdptndir II G SITV V I L LG I SVA G ME W EAK A QVILLV I LL 335
Cdd:pfam00324 80 W nywlsw I TVL A LELTA A SILIQ F W E L V P D IPYLW ------------ VW G AVFL V L L TI I NLV G VK W YGE A EFWFAL I KI 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 336 IAI AN F F I GTV I PSNNEKKSR G -- F FNYQASIFAE NF G P R F T KG eg F F SVF A I F F P A A TGI LAGANIS G DLED P QDA IP R 413
Cdd:pfam00324 148 IAI IG F I I VGI I LLSGGNPND G ai F RYLGDNGGKN NF P P G F G KG -- F I SVF V I A F F A F TGI ELVGIAA G EVKN P EKS IP K 225
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 414 GTMLA I FIT T VA Y LGVAICV G AC V VRDAT G NM ND TIIS gmncngsaacglgydfsrcrhepcq YGLMNN F QVMSMV SG FG 493
Cdd:pfam00324 226 AILQV I WRI T IF Y ILSLLAI G LL V PWNDP G LL ND SASA ------------------------- ASPFVI F FKFLGI SG LA 280
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 494 PLI T A G I FS A T LS S A LA SL V S APKVFQA L CK D NIYK alq F F A K GYG K NNE PLR GYILTFL I AMAFI L I A E LN TI ap I IS N 573
Cdd:pfam00324 281 PLI N A V I LT A A LS A A NS SL Y S GSRMLYS L AR D GLAP --- K F L K KVD K RGV PLR AILVSMV I SLLAL L L A S LN PA -- I VF N 355
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 574 F F LA SYA L INFSCFHASYAKSPGW R P A YGIYNMWVSLFGAVLCCAVMF VI NWW AA V I TYV I EF FLY VYVTCKKPDV NWG S 653
Cdd:pfam00324 356 F L LA ISG L SGLIVWGLISLSHLRF R K A FKYQGRSIDELPFKAPLGPLG VI LGL AA I I IIL I IQ FLY AFLPVPGGPK NWG A 435
490 500 510
....*....|....*....|....*....|..
gi 212276464 654 STQ A LS Y VSA L DNALE L TT V ED HVKN FR PQ CI 685
Cdd:pfam00324 436 GSF A AA Y LIV L LFLII L IG V KL HVKN WK PQ LL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
190-649
2.36e-37
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 146.58
E-value: 2.36e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 190 N I W G VML F IRLSWIV G E AG i GLGV L II L LSTMVTSITG LS TSAI A TN g F V R G GGAY YLIS R S LGP EF G GSI G LIFAFANA 269
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG - PAAI L AW L IAGLLALLVA LS YAEL A SA - F P R A GGAY TYAR R A LGP LL G FLA G WALLLSYV 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 270 V AVA MYV V G F AETVVD L L kesdsmmvd P TNDIRI I GSITVVI L LGISVA G MEWE AK AQV IL L V IL L IAIAN F FIG tvips 349
Cdd:COG0531 103 L AVA AVA V A F GGYLSS L F --------- P AGGSVL I ALVLILL L TLLNLR G VKES AK VNN IL T V LK L LVLLL F IVV ----- 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 350 nnekksr G F F NYQASI F A e N F G P RFTKGE G FFSVF A IF F P A A TG IL A G AN ISGDLED P QDA IPR GTM L AIF I TT V A Y LG V 429
Cdd:COG0531 169 ------- G L F AFDPAN F T - P F L P AGGGLS G VLAAL A LA F F A F TG FE A I AN LAEEAKN P KRN IPR AII L SLL I VG V L Y IL V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 430 AICVGAC V VR D ATGNMNDTI isgmncngsaacglgydfsrcrhepcqyglmnn FQVMSM V S G -- FGP LI TA G IFSAT L SS 507
Cdd:COG0531 241 SLALTGV V PY D ELAASGAPL --------------------------------- ADAAEA V F G pw GAI LI AL G ALLSL L GA 287
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 508 AL AS LVS A PKVFQ A LCK D NI yk ALQF FAK GYGKNNE P LRGYI LT FL IA MAFI L I -- A ELNTI A PII S NFF L AS Y A L INFS 585
Cdd:COG0531 288 LN AS ILG A SRLLY A MAR D GL -- LPKV FAK VHPRFGT P VNAIL LT GV IA LLLL L L ga A SFTAL A SLA S VGV L LA Y L L VALA 365
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 212276464 586 CFHASY a KS P GWRPAYGIYNMWVSLF G AV LC CAVMFVINWW A --- AVITYV I EFF LY VYVTCKK P DV 649
Cdd:COG0531 366 VIVLRR - RR P DLPRPFRVPLPLIPIL G IL LC LFLLYLLGPG A lli GLVLLA I GLL LY LLYRRRH P KL 431
AA_permease_N
pfam08403 Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid ...
90-157
1.37e-36
Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid permease domain (pfam00324) in metazoan Na-K-Cl cotransporters.
Pssm-ID: 429977
Cd Length: 70
Bit Score: 132.18
E-value: 1.37e-36
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 90 D S H TN TYYLQTFGHNT M DAVP K I EY YRNTGS I SG P K VN RPSL L E I H E QL A KN V -- AV TPS S A D R V A NGDG 157
Cdd:pfam08403 1 D T H GS TYYLQTFGHNT L DAVP R I DF YRNTGS V SG V K KS RPSL A E L H S QL K KN S al AV AEG S V D G V E NGDG 70
AA_permease_2
pfam13520 Amino acid permease;
207-643
1.14e-15
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 80.82
E-value: 1.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 207 A G IGLGVLIILLSTMVT S ITGLSTS A IATNGFV R G GG A Y YLISRSL G PEFGGSI G LIFA FA NAVAV A MYVVGF A ETVVDL 286
Cdd:pfam13520 27 S G GPALIVWGWIAAIIF S LAVGLVY A ELSSALP R S GG I Y VYLENAF G KFVAFLA G WSNW FA YVLGL A SSASVA A SYLLSA 106
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 287 L KES dsm M V DP T NDIRI I GSITVV I LLG I SVA G MEWE AK A Q V IL LVIL L IAIANFF I GTVIP snne KKSR G F FN Y q A S IF 366
Cdd:pfam13520 107 L GPD --- L V PT T WLTYG I AIAILI I FAI I NIR G VRES AK I Q N IL GILK L LLPLILI I ILGLV ---- TADG G G FN L - L S GE 178
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 367 AEN F G P RFTK G eg F F SV F AIFFPAA TG ILAG AN I S G dl E DPQDAI P RGTMLAIF I TT V A Y LG V A I CVGAC V VR D ATGNMN 446
Cdd:pfam13520 179 WHT F F P DGWP G -- V F AG F LGVLWSF TG FESA AN V S E -- E VKKRNV P KAIFIGVI I VG V L Y IL V N I AFFGV V PD D EIALSS 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 447 DTIISG mncngsaacglgydfsrcrhepcqy G L MNNFQVMSMVSGF gpl ITAGIFSAT L SSALASL V S A PKVFQ AL CK D N 526
Cdd:pfam13520 255 GLGQVA ------------------------- A L LFQAVGGKWGAII --- VVILLALSL L GAVNTAI V G A SRLLY AL AR D G 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 212276464 527 IYKALQ FFAK g YG K NNE P L R GY ILT FLIAMAFI L I ----- A EL N TIAPIISNFF L A SY A L INFSCFHASYAKSPGW R pay 601
Cdd:pfam13520 307 VLPFSR FFAK - VN K FGS P I R AI ILT AILSLILL L L fllsp A AY N ALLSLSAYGY L L SY L L PIIGLLILRKKRPDLG R --- 382
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 212276464 602 g I YNM W VSLFGAV L CCAVMF V INWWAA V ITYVIEFFL Y VYVT 643
Cdd:pfam13520 383 - I PGR W PVAIFGI L FSLFLI V ALFFPP V GPATGSSLN Y AIIL 423
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
