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Conserved domains on  [gi|115503708|sp|Q1KLY2|]
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RecName: Full=Cathelicidin antimicrobial peptide; Contains: RecName: Full=Antibacterial peptide FALL-39; AltName: Full=FALL-39 peptide antibiotic; Contains: RecName: Full=Antibacterial peptide LL-37; Flags: Precursor

Protein Classification

Cathelicidins and CAP18_C domain-containing protein( domain architecture ID 10461573)

Cathelicidins and CAP18_C domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cathelicidins pfam00666
Cathelicidin; A novel protein family, showing a conserved proregion and a variable ...
 31-131 3.99e-63

Cathelicidin; A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins.


:

Pssm-ID: 395539  Cd Length: 101  Bit Score: 189.25  E-value: 3.99e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115503708   31 QVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCVG 110
Cdd:pfam00666   1 QRLSYREAVLRAVDQFNEQSSEANLYRLLELDPPPQDDEDPDTPKPVSFRVKETVCPRTTQQPPEQCDFKENGLVKRCVG 80

                          90       100
                  ....*....|....*....|.
gi 115503708  111 TVILNQARDSFDISCDKDNRR 131
Cdd:pfam00666  81 TVTLNQARDSFDIRCNEDQSR 101
CAP18_C pfam12153
LPS binding domain of CAP18 (C terminal); This domain family is found in eukaryotes, and is ...
 137-162 3.51e-08

LPS binding domain of CAP18 (C terminal); This domain family is found in eukaryotes, and is approximately 30 amino acids in length, and the family is found in association with pfam00666. CAP18 is a protein which is derived from rabbit granulocytes. It has two domains, an N terminal DUF and a C terminal Gram negative LPS binding domain. This domain is the C terminal domain.


:

Pssm-ID: 403395  Cd Length: 27  Bit Score: 46.88  E-value: 3.51e-08
                          10        20
                  ....*....|....*....|....*.
gi 115503708  137 NFFRKAREKIGKEFKRIVQRIKDFLQ 162
Cdd:pfam12153   1 GFLRKGGEKIGEKLKKIGQKIKDFFQ 26
 
Name Accession Description Interval E-value
Cathelicidins pfam00666
Cathelicidin; A novel protein family, showing a conserved proregion and a variable ...
 31-131 3.99e-63

Cathelicidin; A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins.


Pssm-ID: 395539  Cd Length: 101  Bit Score: 189.25  E-value: 3.99e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115503708   31 QVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCVG 110
Cdd:pfam00666   1 QRLSYREAVLRAVDQFNEQSSEANLYRLLELDPPPQDDEDPDTPKPVSFRVKETVCPRTTQQPPEQCDFKENGLVKRCVG 80

                          90       100
                  ....*....|....*....|.
gi 115503708  111 TVILNQARDSFDISCDKDNRR 131
Cdd:pfam00666  81 TVTLNQARDSFDIRCNEDQSR 101
CAP18_C pfam12153
LPS binding domain of CAP18 (C terminal); This domain family is found in eukaryotes, and is ...
 137-162 3.51e-08

LPS binding domain of CAP18 (C terminal); This domain family is found in eukaryotes, and is approximately 30 amino acids in length, and the family is found in association with pfam00666. CAP18 is a protein which is derived from rabbit granulocytes. It has two domains, an N terminal DUF and a C terminal Gram negative LPS binding domain. This domain is the C terminal domain.


Pssm-ID: 403395  Cd Length: 27  Bit Score: 46.88  E-value: 3.51e-08
                          10        20
                  ....*....|....*....|....*.
gi 115503708  137 NFFRKAREKIGKEFKRIVQRIKDFLQ 162
Cdd:pfam12153   1 GFLRKGGEKIGEKLKKIGQKIKDFFQ 26
 
Name Accession Description Interval E-value
Cathelicidins pfam00666
Cathelicidin; A novel protein family, showing a conserved proregion and a variable ...
 31-131 3.99e-63

Cathelicidin; A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins.


Pssm-ID: 395539  Cd Length: 101  Bit Score: 189.25  E-value: 3.99e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115503708   31 QVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCVG 110
Cdd:pfam00666   1 QRLSYREAVLRAVDQFNEQSSEANLYRLLELDPPPQDDEDPDTPKPVSFRVKETVCPRTTQQPPEQCDFKENGLVKRCVG 80

                          90       100
                  ....*....|....*....|.
gi 115503708  111 TVILNQARDSFDISCDKDNRR 131
Cdd:pfam00666  81 TVTLNQARDSFDIRCNEDQSR 101
CAP18_C pfam12153
LPS binding domain of CAP18 (C terminal); This domain family is found in eukaryotes, and is ...
 137-162 3.51e-08

LPS binding domain of CAP18 (C terminal); This domain family is found in eukaryotes, and is approximately 30 amino acids in length, and the family is found in association with pfam00666. CAP18 is a protein which is derived from rabbit granulocytes. It has two domains, an N terminal DUF and a C terminal Gram negative LPS binding domain. This domain is the C terminal domain.


Pssm-ID: 403395  Cd Length: 27  Bit Score: 46.88  E-value: 3.51e-08
                          10        20
                  ....*....|....*....|....*.
gi 115503708  137 NFFRKAREKIGKEFKRIVQRIKDFLQ 162
Cdd:pfam12153   1 GFLRKGGEKIGEKLKKIGQKIKDFFQ 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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