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Conserved domains on  [gi|190410975|sp|Q53EL9|]
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RecName: Full=Seizure protein 6 homolog; Short=SEZ-6; Short=hSEZ-6; Flags: Precursor

Protein Classification

CUB and CCP domain-containing protein( domain architecture ID 13042673)

protein containing domains PHA03379, CUB, and CCP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 416-526 6.16e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 100.18  E-value: 6.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEApPVYDSYEVE 491
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 190410975 492 YLPIEgLLSSGKHFFVELSTDSSGAAAGMALRYEA 526
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 593-702 2.77e-21

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 89.78  E-value: 2.77e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 593 CSGEITDSA-GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-----DVLTFYDGDDLTARVLGQYSGPR 666
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 190410975 667 SHFKLFTSMADVTIQFQSDPGTSvlgyQQGFVIHFF 702
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 710-766 7.08e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 69.80  E-value: 7.08e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 190410975 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQ 766
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 710-895 1.74e-14

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.69  E-value: 1.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 710 CPELPEIPNGWKSPSQPELvhGTVVTYQCYPGYQVVGSSVLMCQW----DLTWSEDLPSCQRVtSCHDPGDVEHSRRLIS 785
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 786 SPKFPVGATVQYICDQGFVLMGSSILTChdrqaGSPKWSDrAPKClleQLKPCHGLSAPENGARSPEKQLHPAGATIHFS 865
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGEWSD-PPTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                        170       180       190
                 ....*....|....*....|....*....|
gi 190410975 866 CAPGYVLKGQASIKCVPGHPshWSDPPPIC 895
Cdd:PHA02927 234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
Sushi pfam00084
Sushi repeat (SCR repeat);
532-589 6.47e-11

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.66  E-value: 6.47e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975  532 CYEPF-VKYGNFSSSTPTYPVGTTVEFSCDPGYTLeQGSIIIECVDphDPQWNETEPAC 589
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 357-413 1.28e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 46.30  E-value: 1.28e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975 357 CHFPRRPAYGDVTV--TSLHPGGSARFHCATGYQLKGARHLTCLNATQpfWDSKEPVCI 413
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
PHA03379 super family cl33730
EBNA-3A; Provisional
 31-188 1.11e-05

EBNA-3A; Provisional


The actual alignment was detected with superfamily member PHA03379:

Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 49.67  E-value: 1.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  31 QAPGIEETDGELTAAPTPEQPErgVHFVTTAPTLKLLNHHPLLEEFLQEG----LEKGDEElrPALPFQPDPpapfTPSP 106
Cdd:PHA03379 426 EVPQSLETATSHGSAQVPEPPP--VHDLEPGPLHDQHSMAPCPVAQLPPGplqdLEPGDQL--PGVVQDGRP----ACAP 497

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 107 LPRLANQDSRPVFTSPT--PAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAvptlGPGEIASTTPPSRAWTPT 184
Cdd:PHA03379 498 VPAPAGPIVRPWEASLSqvPGVAFAPVMPQPMPVEPVPVPTVALERPVCPAPPLIAMQ----GPGETSGIVRVRERWRPA 573


                 ....
gi 190410975 185 QEGP 188
Cdd:PHA03379 574 PWTP 577
CUB super family cl00049
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 244-352 2.51e-05

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


The actual alignment was detected with superfamily member cd00041:

Pssm-ID: 412131 [Multi-domain]  Cd Length: 113  Bit Score: 44.33  E-value: 2.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 244 CSWNFSGP-EGSLDSPtDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGET-----VTVEGLGGPDPLPLANQSFL 317
Cdd:cd00041    1 CGGTLTAStSGTISSP-NYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 190410975 318 LRGQVIRSPTHQAALRFQSLPPPAGPGtFHFHYQA 352
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRG-FKATYSA 113
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 416-526 6.16e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 100.18  E-value: 6.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEApPVYDSYEVE 491
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 190410975 492 YLPIEgLLSSGKHFFVELSTDSSGAAAGMALRYEA 526
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 593-702 2.77e-21

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 89.78  E-value: 2.77e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 593 CSGEITDSA-GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-----DVLTFYDGDDLTARVLGQYSGPR 666
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 190410975 667 SHFKLFTSMADVTIQFQSDPGTSvlgyQQGFVIHFF 702
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 426-524 3.33e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 83.59  E-value: 3.33e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEApPVYDSYEVEYLPIEGLLSS 501
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 190410975   502 GKHFFVELSTDSSGAAAGMALRY 524
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 602-701 7.33e-18

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 79.74  E-value: 7.33e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   602 GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-----DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMA 676
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSS 80

                           90       100
                   ....*....|....*....|....*.
gi 190410975   677 D-VTIQFQSDPGTSVlgyqQGFVIHF 701
Cdd:smart00042  81 NsLTLTFVSDSSVQK----RGFSARY 102
CUB pfam00431
CUB domain;
416-524 1.13e-16

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 76.56  E-value: 1.13e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  416 CGGVIRNATtGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNvEAPPVYDSYEVE 491
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 190410975  492 YLPiEGLLSSGKHFFVELSTDSSGAAAGMALRY 524
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 710-766 7.08e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 69.80  E-value: 7.08e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 190410975 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQ 766
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 710-765 1.00e-14

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 69.48  E-value: 1.00e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975   710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB pfam00431
CUB domain;
593-701 1.08e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 71.17  E-value: 1.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML-----DIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRS 667
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLtfqdfELEDHDECGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 190410975  668 HFKLFTSMADVTIQFQSDPGTSvlgyQQGFVIHF 701
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDASVQ----KRGFKATY 110
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 710-895 1.74e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.69  E-value: 1.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 710 CPELPEIPNGWKSPSQPELvhGTVVTYQCYPGYQVVGSSVLMCQW----DLTWSEDLPSCQRVtSCHDPGDVEHSRRLIS 785
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 786 SPKFPVGATVQYICDQGFVLMGSSILTChdrqaGSPKWSDrAPKClleQLKPCHGLSAPENGARSPEKQLHPAGATIHFS 865
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGEWSD-PPTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                        170       180       190
                 ....*....|....*....|....*....|
gi 190410975 866 CAPGYVLKGQASIKCVPGHPshWSDPPPIC 895
Cdd:PHA02927 234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
Sushi pfam00084
Sushi repeat (SCR repeat);
710-765 1.94e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 62.90  E-value: 1.94e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975  710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 838-896 8.40e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 8.40e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPICR 896
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 771-830 3.20e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 3.20e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDrqagSPKWSDRAPKC 830
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLE----NGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
532-589 6.47e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.66  E-value: 6.47e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975  532 CYEPF-VKYGNFSSSTPTYPVGTTVEFSCDPGYTLeQGSIIIECVDphDPQWNETEPAC 589
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 535-590 1.00e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 1.00e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975 535 PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLeQGSIIIECVDphDPQWNETEPACR 590
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTE--NGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 535-589 2.94e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 53.68  E-value: 2.94e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 190410975   535 PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLeQGSIIIECVDphDPQWNETEPAC 589
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
771-830 1.26e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.03  E-value: 1.26e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDrqagSPKWSDRAPKC 830
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQE----DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 357-413 1.28e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 46.30  E-value: 1.28e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975 357 CHFPRRPAYGDVTV--TSLHPGGSARFHCATGYQLKGARHLTCLNATQpfWDSKEPVCI 413
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 357-412 1.68e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 1.68e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 190410975   357 CHFPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQpfWDSKEPVC 412
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA03379 PHA03379
EBNA-3A; Provisional
 31-188 1.11e-05

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 49.67  E-value: 1.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  31 QAPGIEETDGELTAAPTPEQPErgVHFVTTAPTLKLLNHHPLLEEFLQEG----LEKGDEElrPALPFQPDPpapfTPSP 106
Cdd:PHA03379 426 EVPQSLETATSHGSAQVPEPPP--VHDLEPGPLHDQHSMAPCPVAQLPPGplqdLEPGDQL--PGVVQDGRP----ACAP 497

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 107 LPRLANQDSRPVFTSPT--PAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAvptlGPGEIASTTPPSRAWTPT 184
Cdd:PHA03379 498 VPAPAGPIVRPWEASLSqvPGVAFAPVMPQPMPVEPVPVPTVALERPVCPAPPLIAMQ----GPGETSGIVRVRERWRPA 573


                 ....
gi 190410975 185 QEGP 188
Cdd:PHA03379 574 PWTP 577
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 244-352 2.51e-05

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 44.33  E-value: 2.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 244 CSWNFSGP-EGSLDSPtDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGET-----VTVEGLGGPDPLPLANQSFL 317
Cdd:cd00041    1 CGGTLTAStSGTISSP-NYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 190410975 318 LRGQVIRSPTHQAALRFQSLPPPAGPGtFHFHYQA 352
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRG-FKATYSA 113
Sushi pfam00084
Sushi repeat (SCR repeat);
357-412 7.37e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 41.33  E-value: 7.37e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 190410975  357 CHFPRRPAYGDVTVT--SLHPGGSARFHCATGYQLKGARHLTCLnaTQPFWDSKEPVC 412
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQ--EDGTWSPPFPEC 56
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 100-184 1.92e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 45.29  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  100 APFTPSPLPRLANQDSR---------------PVFTSPTPAM------AAVPT----QPQSKEGPWSPESESPMLRITAP 154
Cdd:pfam05109 486 SPVTPSPSPRDNGTESKapdmtsptsavttptPNATSPTPAVttptpnATSPTlgktSPTSAVTTPTPNATSPTPAVTTP 565

                          90       100       110
                  ....*....|....*....|....*....|..
gi 190410975  155 LppgPSMAVPTLGPGEIAS--TTPPSRAWTPT 184
Cdd:pfam05109 566 T---PNATIPTLGKTSPTSavTTPTPNATSPT 594
PHA02831 PHA02831
EEV host range protein; Provisional
 704-765 7.33e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 42.67  E-value: 7.33e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975 704 VPRNDTCP----ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Cdd:PHA02831 130 VPKYPVCKlircKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 416-526 6.16e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 100.18  E-value: 6.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEApPVYDSYEVE 491
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 190410975 492 YLPIEgLLSSGKHFFVELSTDSSGAAAGMALRYEA 526
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 593-702 2.77e-21

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 89.78  E-value: 2.77e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 593 CSGEITDSA-GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-----DVLTFYDGDDLTARVLGQYSGPR 666
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 190410975 667 SHFKLFTSMADVTIQFQSDPGTSvlgyQQGFVIHFF 702
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 426-524 3.33e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 83.59  E-value: 3.33e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEApPVYDSYEVEYLPIEGLLSS 501
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 190410975   502 GKHFFVELSTDSSGAAAGMALRY 524
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 602-701 7.33e-18

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 79.74  E-value: 7.33e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   602 GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-----DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMA 676
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSS 80

                           90       100
                   ....*....|....*....|....*.
gi 190410975   677 D-VTIQFQSDPGTSVlgyqQGFVIHF 701
Cdd:smart00042  81 NsLTLTFVSDSSVQK----RGFSARY 102
CUB pfam00431
CUB domain;
416-524 1.13e-16

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 76.56  E-value: 1.13e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  416 CGGVIRNATtGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNvEAPPVYDSYEVE 491
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 190410975  492 YLPiEGLLSSGKHFFVELSTDSSGAAAGMALRY 524
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 710-766 7.08e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 69.80  E-value: 7.08e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 190410975 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQ 766
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 710-765 1.00e-14

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 69.48  E-value: 1.00e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975   710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB pfam00431
CUB domain;
593-701 1.08e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 71.17  E-value: 1.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML-----DIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRS 667
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLtfqdfELEDHDECGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 190410975  668 HFKLFTSMADVTIQFQSDPGTSvlgyQQGFVIHF 701
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDASVQ----KRGFKATY 110
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 710-895 1.74e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.69  E-value: 1.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 710 CPELPEIPNGWKSPSQPELvhGTVVTYQCYPGYQVVGSSVLMCQW----DLTWSEDLPSCQRVtSCHDPGDVEHSRRLIS 785
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 786 SPKFPVGATVQYICDQGFVLMGSSILTChdrqaGSPKWSDrAPKClleQLKPCHGLSAPENGARSPEKQLHPAGATIHFS 865
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGEWSD-PPTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                        170       180       190
                 ....*....|....*....|....*....|
gi 190410975 866 CAPGYVLKGQASIKCVPGHPshWSDPPPIC 895
Cdd:PHA02927 234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 731-892 8.28e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 72.76  E-value: 8.28e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 731 GTVVTYQCYPGY--QVVGSSVLMCQ---WDLtwsedLPSCQRvTSCHDPGDVEHSRRLISSPKFpvGATVQYICDQGFVL 805
Cdd:PHA02927  47 GDTIEYLCLPGYrkQKMGPIYAKCTgtgWTL-----FNQCIK-RRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 806 MGSSILTCHDRQAGSPKWSDRAPKCllEQLKpCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGhp 885
Cdd:PHA02927 119 IGESKSYCELGSTGSMVWNPEAPIC--ESVK-CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG-- 193


                 ....*..
gi 190410975 886 sHWSDPP 892
Cdd:PHA02927 194 -EWSDPP 199
Sushi pfam00084
Sushi repeat (SCR repeat);
710-765 1.94e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 62.90  E-value: 1.94e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975  710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 838-896 8.40e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 8.40e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPICR 896
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 771-830 3.20e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 3.20e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDrqagSPKWSDRAPKC 830
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLE----NGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 771-830 5.88e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.63  E-value: 5.88e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDrqagSPKWSDRAPKC 830
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTE----NGGWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
532-589 6.47e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.66  E-value: 6.47e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975  532 CYEPF-VKYGNFSSSTPTYPVGTTVEFSCDPGYTLeQGSIIIECVDphDPQWNETEPAC 589
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 838-895 2.01e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 2.01e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 190410975   838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPIC 895
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN--GTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 535-590 1.00e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 1.00e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975 535 PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLeQGSIIIECVDphDPQWNETEPACR 590
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTE--NGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 535-589 2.94e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 53.68  E-value: 2.94e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 190410975   535 PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLeQGSIIIECVDphDPQWNETEPAC 589
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 771-896 4.22e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 58.91  E-value: 4.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTChDRQAGSPKWSDRAPKCLleqLKPCHGLSAPENGARS 850
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTC-IKDKNNAIWSNKAPFCM---LKECNDPPSIINGKIY 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 190410975 851 PEKQLHPAGATIHFSC----APGYVLKGQASIKCVpgHPSHWSDPPPICR 896
Cdd:PHA02639  98 NKREMYKVGDEIYYVCnehkGVQYSLVGNEKITCI--QDKSWKPDPPICK 145
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 710-831 7.05e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 57.74  E-value: 7.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDlTWSeDLPSCQrVTSCHDPgdvEHSRRLISS--- 786
Cdd:PHA02927 148 CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG-EWS-DPPTCQ-IVKCPHP---TISNGYLSSgfk 221

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 190410975 787 PKFPVGATVQYICDQGFVLMGSSILTChdrqagSP--KWSDRAPKCL 831
Cdd:PHA02927 222 RSYSYNDNVDFKCKYGYKLSGSSSSTC------SPgnTWQPELPKCV 262
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 709-831 4.34e-08

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 56.25  E-value: 4.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 709 TCPELP----EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDlTWSEdLPSCQRvtSCHDPgdvEHSRRLI 784
Cdd:PHA02954 124 TCPNAEcqplQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTAN-SWNV-IPSCQQ--KCDIP---SLSNGLI 196

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 190410975 785 SSPKFPVGATVQYICDQGFVLMGSSILTCHDrqagsPKWSDRAPKCL 831
Cdd:PHA02954 197 SGSTFSIGGVIHLSCKSGFTLTGSPSSTCID-----GKWNPVLPICV 238
Sushi pfam00084
Sushi repeat (SCR repeat);
771-830 1.26e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.03  E-value: 1.26e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDrqagSPKWSDRAPKC 830
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQE----DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 357-413 1.28e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 46.30  E-value: 1.28e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975 357 CHFPRRPAYGDVTV--TSLHPGGSARFHCATGYQLKGARHLTCLNATQpfWDSKEPVCI 413
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 357-412 1.68e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 1.68e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 190410975   357 CHFPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQpfWDSKEPVC 412
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 710-895 2.14e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.82  E-value: 2.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD---LTWSEDLPSCQrVTSCHDPGDVEHSRRLISS 786
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDknnAIWSNKAPFCM-LKECNDPPSIINGKIYNKR 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 787 PKFPVGATVQYICDQ----GFVLMGSSILTCHDRQAgspkWSDRAPKCLLEQLKpchgLSAPENGARS--PEKQLHPAGA 860
Cdd:PHA02639 101 EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKS----WKPDPPICKMINCR----FPALQNGYINgiPSNKKFYYKT 172

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 190410975 861 TIHFSCAPGYVLKGQASIKCvpGHPSHWSDPPPIC 895
Cdd:PHA02639 173 RVGFSCKSGFDLVGEKYSTC--NINATWFPSIPTC 205
PHA03379 PHA03379
EBNA-3A; Provisional
 31-188 1.11e-05

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 49.67  E-value: 1.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  31 QAPGIEETDGELTAAPTPEQPErgVHFVTTAPTLKLLNHHPLLEEFLQEG----LEKGDEElrPALPFQPDPpapfTPSP 106
Cdd:PHA03379 426 EVPQSLETATSHGSAQVPEPPP--VHDLEPGPLHDQHSMAPCPVAQLPPGplqdLEPGDQL--PGVVQDGRP----ACAP 497

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 107 LPRLANQDSRPVFTSPT--PAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAvptlGPGEIASTTPPSRAWTPT 184
Cdd:PHA03379 498 VPAPAGPIVRPWEASLSqvPGVAFAPVMPQPMPVEPVPVPTVALERPVCPAPPLIAMQ----GPGETSGIVRVRERWRPA 573


                 ....
gi 190410975 185 QEGP 188
Cdd:PHA03379 574 PWTP 577
PHA02831 PHA02831
EEV host range protein; Provisional
 710-831 1.61e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.68  E-value: 1.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 710 CPELPEIPNGWKSPSQPELVHGTVVTYQC----YPGYQVVGSSVLMCqWDLTWSEDLPSCqRVTSCHDPGdVEHSRRLIS 785
Cdd:PHA02831  78 CKDPVTILNGYIKNKKDQYSFGDSVTYACkvnkLEKYSIVGNETVKC-INKQWVPKYPVC-KLIRCKYPA-LQNGFLNVF 154

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 190410975 786 SPKFPVGATVQYICDQGFVLMGSSILTCHDRQAgspkWSDRAPKCL 831
Cdd:PHA02831 155 EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI----WYPGIPKCV 196
Sushi pfam00084
Sushi repeat (SCR repeat);
838-895 2.43e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 2.43e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 190410975  838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPIC 895
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 244-352 2.51e-05

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 44.33  E-value: 2.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 244 CSWNFSGP-EGSLDSPtDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGET-----VTVEGLGGPDPLPLANQSFL 317
Cdd:cd00041    1 CGGTLTAStSGTISSP-NYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 190410975 318 LRGQVIRSPTHQAALRFQSLPPPAGPGtFHFHYQA 352
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRG-FKATYSA 113
PHA02817 PHA02817
EEV Host range protein; Provisional
 708-830 4.10e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.09  E-value: 4.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPG-----YQVVGSSVLMCQWDLTWSEDLPSCQrVTSCHDPG-DVEHSR 781
Cdd:PHA02817  22 NKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK-IIRCRFPAlQNGFVN 100

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 190410975 782 RLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAgspkWSDRAPKC 830
Cdd:PHA02817 101 GIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSS----WIPKVPIC 145
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
89-222 6.13e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 6.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  89 RPALPFQPDPPAPFTPSPLPRLANQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGP 168
Cdd:PRK12323 393 AAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPV 472

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 190410975 169 GEIASTTPPSRA-----------WTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDE 222
Cdd:PRK12323 473 AAAAAAAPARAApaaapapadddPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDA 537
Sushi pfam00084
Sushi repeat (SCR repeat);
357-412 7.37e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 41.33  E-value: 7.37e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 190410975  357 CHFPRRPAYGDVTVT--SLHPGGSARFHCATGYQLKGARHLTCLnaTQPFWDSKEPVC 412
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQ--EDGTWSPPFPEC 56
PHA03247 PHA03247
large tegument protein UL36; Provisional
 90-188 7.64e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 7.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   90 PALPFQPDPPAPFTPSPLPRLANQDSRPVFTS--PTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPS---MAVP 164
Cdd:PHA03247 2733 PALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAdppAAVL 2812

                          90       100
                  ....*....|....*....|....
gi 190410975  165 TLGPGEIASTTPPSRAWTPTQEGP 188
Cdd:PHA03247 2813 APAAALPPAASPAGPLPPPTSAQP 2836
PHA03247 PHA03247
large tegument protein UL36; Provisional
 25-194 1.36e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 1.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   25 PTVGKGQAPGIEETDGELTAAPTPEQPErgvhfvTTAPTLKLLNHHPLLEEflqegLEKGDEELRPALPFQPDPPAPFTP 104
Cdd:PHA03247 2593 PQSARPRAPVDDRGDPRGPAPPSPLPPD------THAPDPPPPSPSPAANE-----PDPHPPPTVPPPERPRDDPAPGRV 2661

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  105 SPlPRLANQDSRPVFTSPTP----------AMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIAST 174
Cdd:PHA03247 2662 SR-PRRARRLGRAAQASSPPqrprrraarpTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPA 2740

                         170       180
                  ....*....|....*....|
gi 190410975  175 TPPSRAWTPTQEGPGDMGRP 194
Cdd:PHA03247 2741 PPAVPAGPATPGGPARPARP 2760
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 24-179 1.81e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.55  E-value: 1.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   24 APTVGKGQAPGIEETDGELTAAPTPEQPERGVHFVTTAPTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFT 103
Cdd:PHA03307   54 TVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPD 133

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975  104 PSPLPRLANQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSR 179
Cdd:PHA03307  134 LSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRR 209
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 100-184 1.92e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 45.29  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  100 APFTPSPLPRLANQDSR---------------PVFTSPTPAM------AAVPT----QPQSKEGPWSPESESPMLRITAP 154
Cdd:pfam05109 486 SPVTPSPSPRDNGTESKapdmtsptsavttptPNATSPTPAVttptpnATSPTlgktSPTSAVTTPTPNATSPTPAVTTP 565

                          90       100       110
                  ....*....|....*....|....*....|..
gi 190410975  155 LppgPSMAVPTLGPGEIAS--TTPPSRAWTPT 184
Cdd:pfam05109 566 T---PNATIPTLGKTSPTSavTTPTPNATSPT 594
PHA03247 PHA03247
large tegument protein UL36; Provisional
 90-199 4.65e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 4.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   90 PALPFQPDPPAPFTPSPLPRLANQDSRPVFTSpTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPG 169
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTS-RARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP 2631

                          90       100       110
                  ....*....|....*....|....*....|
gi 190410975  170 EIASTTPPSRAWTPTQEGPGDMGRPWVAEV 199
Cdd:PHA03247 2632 SPAANEPDPHPPPTVPPPERPRDDPAPGRV 2661
PHA02831 PHA02831
EEV host range protein; Provisional
 704-765 7.33e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 42.67  E-value: 7.33e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 190410975 704 VPRNDTCP----ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Cdd:PHA02831 130 VPKYPVCKlircKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
PHA02639 PHA02639
EEV host range protein; Provisional
 710-831 1.95e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 41.57  E-value: 1.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 710 CPELPEIPNGWKSPSQPELVHGTVVTYQC--YPG--YQVVGSSVLMCQWDLTWSEDLPSCQRVtSCHDPG-DVEHSRRLI 784
Cdd:PHA02639  85 CNDPPSIINGKIYNKREMYKVGDEIYYVCneHKGvqYSLVGNEKITCIQDKSWKPDPPICKMI-NCRFPAlQNGYINGIP 163

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 190410975 785 SSPKFPVGATVQYICDQGFVLMGSSILTCHDrqagSPKWSDRAPKCL 831
Cdd:PHA02639 164 SNKKFYYKTRVGFSCKSGFDLVGEKYSTCNI----NATWFPSIPTCV 206
PHA02831 PHA02831
EEV host range protein; Provisional
 736-949 2.48e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 40.75  E-value: 2.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 736 YQCYPGYQVVgssVLMCQwDLTWSEDlPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICD----QGFVLMGSSIL 811
Cdd:PHA02831  48 YKCNNNFDKV---FVTCN-NGSWSTK-NMCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSIVGNETV 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 812 TCHDRQagspkWSDRAPKCLLEQLKpchgLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCvpGHPSHWSDP 891
Cdd:PHA02831 123 KCINKQ-----WVPKYPVCKLIRCK----YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTC--DINSIWYPG 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 190410975 892 PPICRAASLDGFYNSRSL--DVAKAPAASST---LDAAHIAAAIFLPLVAMVLLVGGVYFYFS 949
Cdd:PHA02831 192 IPKCVKDKVHNEIQPNYLfdDLDEDFNNSTTnynMQQNIITIIILLSIICFIFVLGLIALFLS 254
PHA03247 PHA03247
large tegument protein UL36; Provisional
 89-183 2.60e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   89 RPALP--------FQPDPPAPFTPSPLPRlANQDSRPVFTSP------TPAMAAVPTQPQSKEGPWSPESESPmlRITAP 154
Cdd:PHA03247 2685 RRAARptvgsltsLADPPPPPPTPEPAPH-ALVSATPLPPGPaaarqaSPALPAAPAPPAVPAGPATPGGPAR--PARPP 2761

                          90       100
                  ....*....|....*....|....*....
gi 190410975  155 LPPGPSMAVPTLGPgeiaSTTPPSRAWTP 183
Cdd:PHA03247 2762 TTAGPPAPAPPAAP----AAGPPRRLTRP 2786
PHA02817 PHA02817
EEV Host range protein; Provisional
 764-895 3.41e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 40.31  E-value: 3.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975 764 SCQRVTSCHDPgDVEHSRRLISSPKFPVGATVQYICDQG-----FVLMGSSILTCHDrqagSPKWSDRAPKClleQLKPC 838
Cdd:PHA02817  18 LCDLNKCCYPP-SIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEK----DGKWNKEFPVC---KIIRC 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975 839 HgLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCvpGHPSHWSDPPPIC 895
Cdd:PHA02817  90 R-FPALQNGFVNgiPDSKKFYYESEVSFSCKPGFVLIGTKYSVC--GINSSWIPKVPIC 145
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 88-187 4.30e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.95  E-value: 4.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  88 LRPALPFQPDPPAPFTPSPLprlanQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESPmlRITAPLPPGPSMAVPTLG 167
Cdd:PRK14950 360 LVPVPAPQPAKPTAAAPSPV-----RPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPP--RPVAPPVPHTPESAPKLT 432

                         90       100
                 ....*....|....*....|.
gi 190410975 168 PGEI-ASTTPPSRAWTPTQEG 187
Cdd:PRK14950 433 RAAIpVDEKPKYTPPAPPKEE 453
MCPVI pfam02993
Minor capsid protein VI; This minor capsid protein may act as a link between the external ...
 71-147 4.43e-03

Minor capsid protein VI; This minor capsid protein may act as a link between the external capsid and the internal DNA-protein core. The C-terminal 11 residues may function as a protease cofactor leading to enzyme activation.


Pssm-ID: 367287  Cd Length: 225  Bit Score: 39.99  E-value: 4.43e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975   71 PLLEEFLQEGLekgdeelRPALPFQPDPPAPFTPS--PLPRLANQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESP 147
Cdd:pfam02993 128 PSYEEAVKQGE-------PTTRPIAPMATGVLTPVtlDLPPPVDEVQPPVLSSPSAVVVTRPSRASLRRAASGPRRKRP 199
PHA03247 PHA03247
large tegument protein UL36; Provisional
 44-183 4.53e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 4.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   44 AAPTPEQPERGVHFVTTAPTLKLLNHHPLLEEflqegLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFTSPT 123
Cdd:PHA03247 2676 ASSPPQRPRRRAARPTVGSLTSLADPPPPPPT-----PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  124 PAMAAVPTQPQSKEGPWSPesESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSRAWTP 183
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAP--APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPP 2808
PHA03247 PHA03247
large tegument protein UL36; Provisional
 89-197 5.60e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 5.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   89 RPALPFQPDPPAPFTPSPLPRLANQDSRPVFTSPTPAMAAVPTQPQskegpwspesespmlrITAPLPPGPSMAVPTLGP 168
Cdd:PHA03247  377 RASLPTRKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTP----------------VPASAPPPPATPLPSAEP 440

                          90       100
                  ....*....|....*....|....*....
gi 190410975  169 GEIASTTPPSRAWTPTQEGPGDMGRPWVA 197
Cdd:PHA03247  441 GSDDGPAPPPERQPPAPATEPAPDDPDDA 469
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 93-188 6.03e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 40.52  E-value: 6.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975   93 PFQPDPPAPFTPSPLPRLANQDSRP-VFTSPTPAMAAVPTQPQSKEGPWSPESESPML---RITAPLPPGPSMAVPTLGP 168
Cdd:pfam03154 180 AASPPSPPPPGTTQAATAGPTPSAPsVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLhpqRLPSPHPPLQPMTQPPPPS 259

                          90       100
                  ....*....|....*....|
gi 190410975  169 GEIASTTPPSRAWTPTQEGP 188
Cdd:pfam03154 260 QVSPQPLPQPSLHGQMPPMP 279
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 79-212 6.61e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 6.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  79 EGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPG 158
Cdd:PRK07764 379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPP 458

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 190410975 159 PSMAVPTLGPGEIASTTPPSRAWTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTI 212
Cdd:PRK07764 459 AAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATL 512
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 89-186 7.57e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 40.10  E-value: 7.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 190410975  89 RPALPFQPDPPAPFTPSPLPRLANQDSRPVFTSPTPAMAAVPTqPQSKEGPWSPESESPmlritAPLPPGPSMAVPTLGP 168
Cdd:PHA03269  67 KPDLAQAPTPAASEKFDPAPAPHQAASRAPDPAVAPQLAAAPK-PDAAEAFTSAAQAHE-----APADAGTSAASKKPDP 140

                         90
                 ....*....|....*...
gi 190410975 169 GEIASTTPPSRAWTPTQE 186
Cdd:PHA03269 141 AAHTQHSPPPFAYTRSME 158
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 710-767 8.91e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 39.25  E-value: 8.91e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 190410975 710 CPElPEIPNGWKSPS-QPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQR 767
Cdd:PHA02927 206 CPH-PTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCVR 263
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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