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Conserved domains on  [gi|158706490|sp|Q8TF20|]
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RecName: Full=Zinc finger protein 721

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 12142358)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
206-596 5.44e-12

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.95  E-value: 5.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 206 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKC--KECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKH 283
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 284 RRIHT----GEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYV-HRRIHTGEKPYKCEDCGKAF 358
Cdd:COG5048  111 SSSSSnsndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLISS 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 359 GRYTALNQHKKIHTGEKPYK----CEECGKaFNSSTNLTAHKRIHTREKPYTCEdRGRAFGLSTNLNEYKKIHTGDKPYk 434
Cdd:COG5048  191 NVSTSIPSSSENSPLSSSYSipssSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSSSDSSSSASESPRSSLPT- 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 435 ckecgKAFIHSLHLNKHEKIHTGK-KPYKCKQCGKVITSSSSFAKHKR--IHTGE--KPFECLE--CGKAFTSSTTLTKH 507
Cdd:COG5048  268 -----ASSQSSSPNESDSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 508 RRIHTGEKPYTC--EVCGKAFRQSAILY-----VHRRIHTGEKPYTCE--ECGKTFRQSANLYVHRRIHTGEKP--YKCE 576
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNP 422

                        410       420
                 ....*....|....*....|
gi 158706490 577 ECGKAFGRYTDLNQHKKIHT 596
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
430-873 4.87e-11

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 430 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKC--KQCGKVITSSSSFAKHKRIHTGEKPFECLECG------KAFTSS 501
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsnskASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 502 TTLTKHRRIHTGEKPYTCevCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYV-HRRIHTGEKPYKCEECGK 580
Cdd:COG5048  111 SSSSSNSNDNNLLSSHSL--PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLI 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 581 AFGRYTDLNQHKKIHTGEKLYKceecgkdfvwYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE 660
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYS----------IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 661 ECGKAFGWSIALNQHKKIHTGE-------KPYKCEECGKAFSRSRNLTTHRRvhtrekpykcedrgrsfgwstnlneyKK 733
Cdd:COG5048  259 ESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLR--------------------------SV 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 734 IHTGDKL--YKCKE--CGKVFKQSSHLNRHEKIHTGKKPYKCK--ECGKVITSSS------SFAKHKRIHTgEKPFKCL- 800
Cdd:COG5048  313 NHSGESLkpFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLs 391

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158706490 801 -ECGKAFTSSTTLTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKPYTCgECGKTFRQSANLYAHKK 873
Cdd:COG5048  392 nSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
139-164 3.56e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.56e-04
                          10        20
                  ....*....|....*....|....*.
gi 158706490  139 DLNQHKKIHTGEKPYKCEECGKAFNR 164
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 149-229 1.49e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 149 GEKPYKCE--ECGKAFNRSTNLTAHKRI-HNREKAYTGEDRDRAFGWSTNlneykkihtgDKPYKCKECGKAFMHSSHLN 225
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHMLHgHQNQKLHENPSPEKMNIFSAK----------DKPYRCEVCDKRYKNLNGLK 415


                 ....
gi 158706490 226 KHEK 229
Cdd:COG5189  416 YHRK 419
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
206-596 5.44e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.95  E-value: 5.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 206 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKC--KECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKH 283
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 284 RRIHT----GEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYV-HRRIHTGEKPYKCEDCGKAF 358
Cdd:COG5048  111 SSSSSnsndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLISS 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 359 GRYTALNQHKKIHTGEKPYK----CEECGKaFNSSTNLTAHKRIHTREKPYTCEdRGRAFGLSTNLNEYKKIHTGDKPYk 434
Cdd:COG5048  191 NVSTSIPSSSENSPLSSSYSipssSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSSSDSSSSASESPRSSLPT- 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 435 ckecgKAFIHSLHLNKHEKIHTGK-KPYKCKQCGKVITSSSSFAKHKR--IHTGE--KPFECLE--CGKAFTSSTTLTKH 507
Cdd:COG5048  268 -----ASSQSSSPNESDSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 508 RRIHTGEKPYTC--EVCGKAFRQSAILY-----VHRRIHTGEKPYTCE--ECGKTFRQSANLYVHRRIHTGEKP--YKCE 576
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNP 422

                        410       420
                 ....*....|....*....|
gi 158706490 577 ECGKAFGRYTDLNQHKKIHT 596
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
430-873 4.87e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 430 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKC--KQCGKVITSSSSFAKHKRIHTGEKPFECLECG------KAFTSS 501
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsnskASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 502 TTLTKHRRIHTGEKPYTCevCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYV-HRRIHTGEKPYKCEECGK 580
Cdd:COG5048  111 SSSSSNSNDNNLLSSHSL--PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLI 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 581 AFGRYTDLNQHKKIHTGEKLYKceecgkdfvwYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE 660
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYS----------IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 661 ECGKAFGWSIALNQHKKIHTGE-------KPYKCEECGKAFSRSRNLTTHRRvhtrekpykcedrgrsfgwstnlneyKK 733
Cdd:COG5048  259 ESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLR--------------------------SV 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 734 IHTGDKL--YKCKE--CGKVFKQSSHLNRHEKIHTGKKPYKCK--ECGKVITSSS------SFAKHKRIHTgEKPFKCL- 800
Cdd:COG5048  313 NHSGESLkpFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLs 391

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158706490 801 -ECGKAFTSSTTLTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKPYTCgECGKTFRQSANLYAHKK 873
Cdd:COG5048  392 nSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
671-696 3.49e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.49e-04
                          10        20
                  ....*....|....*....|....*.
gi 158706490  671 ALNQHKKIHTGEKPYKCEECGKAFSR 696
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
363-388 3.49e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.49e-04
                          10        20
                  ....*....|....*....|....*.
gi 158706490  363 ALNQHKKIHTGEKPYKCEECGKAFNS 388
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
139-164 3.56e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.56e-04
                          10        20
                  ....*....|....*....|....*.
gi 158706490  139 DLNQHKKIHTGEKPYKCEECGKAFNR 164
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 149-229 1.49e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 149 GEKPYKCE--ECGKAFNRSTNLTAHKRI-HNREKAYTGEDRDRAFGWSTNlneykkihtgDKPYKCKECGKAFMHSSHLN 225
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHMLHgHQNQKLHENPSPEKMNIFSAK----------DKPYRCEVCDKRYKNLNGLK 415


                 ....
gi 158706490 226 KHEK 229
Cdd:COG5189  416 YHRK 419
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
206-596 5.44e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.95  E-value: 5.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 206 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKC--KECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKH 283
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 284 RRIHT----GEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYV-HRRIHTGEKPYKCEDCGKAF 358
Cdd:COG5048  111 SSSSSnsndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLISS 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 359 GRYTALNQHKKIHTGEKPYK----CEECGKaFNSSTNLTAHKRIHTREKPYTCEdRGRAFGLSTNLNEYKKIHTGDKPYk 434
Cdd:COG5048  191 NVSTSIPSSSENSPLSSSYSipssSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSSSDSSSSASESPRSSLPT- 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 435 ckecgKAFIHSLHLNKHEKIHTGK-KPYKCKQCGKVITSSSSFAKHKR--IHTGE--KPFECLE--CGKAFTSSTTLTKH 507
Cdd:COG5048  268 -----ASSQSSSPNESDSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 508 RRIHTGEKPYTC--EVCGKAFRQSAILY-----VHRRIHTGEKPYTCE--ECGKTFRQSANLYVHRRIHTGEKP--YKCE 576
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNP 422

                        410       420
                 ....*....|....*....|
gi 158706490 577 ECGKAFGRYTDLNQHKKIHT 596
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
430-873 4.87e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 430 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKC--KQCGKVITSSSSFAKHKRIHTGEKPFECLECG------KAFTSS 501
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsnskASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 502 TTLTKHRRIHTGEKPYTCevCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYV-HRRIHTGEKPYKCEECGK 580
Cdd:COG5048  111 SSSSSNSNDNNLLSSHSL--PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLI 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 581 AFGRYTDLNQHKKIHTGEKLYKceecgkdfvwYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE 660
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYS----------IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 661 ECGKAFGWSIALNQHKKIHTGE-------KPYKCEECGKAFSRSRNLTTHRRvhtrekpykcedrgrsfgwstnlneyKK 733
Cdd:COG5048  259 ESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLR--------------------------SV 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 734 IHTGDKL--YKCKE--CGKVFKQSSHLNRHEKIHTGKKPYKCK--ECGKVITSSS------SFAKHKRIHTgEKPFKCL- 800
Cdd:COG5048  313 NHSGESLkpFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLs 391

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158706490 801 -ECGKAFTSSTTLTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKPYTCgECGKTFRQSANLYAHKK 873
Cdd:COG5048  392 nSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
143-557 1.56e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.33  E-value: 1.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 143 HKKIHTGEKPYKC--EECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEY-KKIHTGDKPYKCKECGKAFM 219
Cdd:COG5048   52 HIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLsSSSSNSNDNNLLSSHSLPPS 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 220 HSSHLNKHEKIHTGEKPYKCKEC-GKVISSSSSFAKHKRIHTGEKPFKclecgkAFNISTTLTKHRRIHTGEKPYTCEVC 298
Cdd:COG5048  132 SRDPQLPDLLSISNLRNNPLPGNnSSSVNTPQSNSLHPPLPANSLSKD------PSSNLSLLISSNVSTSIPSSSENSPL 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 299 GKAFRQSANLYVHRRIHTgEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGE---- 374
Cdd:COG5048  206 SSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssek 284

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 375 ---KPYKCEECGKAFNSSTNLTAHKR--IHTREkpytcedrgrafglstnlneykkihtGDKPYKCKE--CGKAFIHSLH 447
Cdd:COG5048  285 gfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGE--------------------------SLKPFSCPYslCGKLFSRNDA 338

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 448 LNKHEKIHTGKKPYKCK--QCGKVITSSS------SFAKHKRIHTgEKPFECL--ECGKAFTSSTTLTKHRRIHTGEKPY 517
Cdd:COG5048  339 LKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPY 417

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 158706490 518 TCE--VCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQS 557
Cdd:COG5048  418 NCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
487-893 2.18e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 2.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 487 KPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQS--AILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHR 564
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 565 RIHTGE-KPYKCEECGKAFGRY---TDLNQHKKIHTGEKLYKCEECGKDFVWYTDLNQQKKIYtgekpykcEECGKAFAP 640
Cdd:COG5048  112 SSSSNSnDNNLLSSHSLPPSSRdpqLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN--------SLSKDPSSN 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 641 STDLNQHTKILTGEQSYKCEECGKAfgWSI-ALNQHKKIHTGEKPYKCEECGKAF-------SRSRNLTTHRRVHTREKP 712
Cdd:COG5048  184 LSLLISSNVSTSIPSSSENSPLSSS--YSIpSSSSDQNLENSSSSLPLTTNSQLSpksllsqSPSSLSSSDSSSSASESP 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 713 YKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRH--EKIHTGK--KPYKCKE--CGKVITSSSSFAK 786
Cdd:COG5048  262 RSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHlrSVNHSGEslKPFSCPYslCGKLFSRNDALKR 341

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 787 HKRIHTGEKPFKC--LECGKAFTSSTT-----LTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKP--YTC 855
Cdd:COG5048  342 HILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKN 421

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 158706490 856 GECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQS 893
Cdd:COG5048  422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
291-723 6.65e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 6.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 291 KPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCG--ECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAfgRYTALNQHK 368
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPL--SNSKASSSS 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 369 KIHTGEKPYKCE-ECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLH 447
Cdd:COG5048  110 LSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLIS 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 448 LNKhekIHTGKKPYKCKQCGKVI------------TSSSSFAKHKRIHTGEKPFECleCGKAFTSSTTLTKHRRIHtgek 515
Cdd:COG5048  190 SNV---STSIPSSSENSPLSSSYsipssssdqnleNSSSSLPLTTNSQLSPKSLLS--QSPSSLSSSDSSSSASES---- 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 516 pYTCEVCGKAFRQSAILYVHRRIHTG-EKPYTCEECGKTFRQSANLYVHRR--IHTGE--KPYKCEE--CGKAFGRYTDL 588
Cdd:COG5048  261 -PRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDAL 339

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 589 NQHKKIHTGEKLYKCeecgkdfvwytDLNQQKKIYTGEKPYKceecgkafaPSTDLNQHTKILTGEQSYKCEECGKAFGW 668
Cdd:COG5048  340 KRHILLHTSISPAKE-----------KLLNSSSKFSPLLNNE---------PPQSLQQYKDLKNDKKSETLSNSCIRNFK 399

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 158706490 669 S---IALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGRSFG 723
Cdd:COG5048  400 RdsnLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRR 457
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
81-480 1.46e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.62  E-value: 1.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490  81 FANSNKDKTrhtgekhFKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYT----------------DLNQHK 144
Cdd:COG5048   25 KSLSNAPRP-------DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrhlrthhnnpsDLNSKS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 145 KIHTGEKPYKCEECGKAFNRSTNL-----------------TAHKRIHNREKAYTGEdrdraFGWSTNLNEY-KKIHTGD 206
Cdd:COG5048   98 LPLSNSKASSSSLSSSSSNSNDNNllsshslppssrdpqlpDLLSISNLRNNPLPGN-----NSSSVNTPQSnSLHPPLP 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 207 KPYKCKECGKAFMHSSHLNKhekIHTGEKPYKCKECGKVISSSSSFAKHKRIHTgEKPFKCLECGKAFNISTTLTKHRRI 286
Cdd:COG5048  173 ANSLSKDPSSNLSLLISSNV---STSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 287 HTGEKPYTCEVCGKAFRQSANLYVHRRIHTGE-------KPYTCGECGKTFRQSANLYVHRR--IHTGE--KPYKC--ED 353
Cdd:COG5048  249 SSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySL 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 354 CGKAFGRYTALNQHKKIHTGEKPYKC--EECGKAFNSSTN-----LTAHKRIHTREKPYTCEDRG--RAFGLSTNLNEYK 424
Cdd:COG5048  329 CGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLSNSciRNFKRDSNLSLHI 408

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 158706490 425 KIHTGDKP--YKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHK 480
Cdd:COG5048  409 ITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 152-312 2.46e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.71  E-value: 2.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 152 PYKCEECGKAFNRSTNL--TAHKRIHNREKAYTGEDRDRAfGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLN---- 225
Cdd:COG5189  260 PSNEEMLYKYISPSQGSaeLFEESSLGFDYEFIHKSVGNK-EIRGGISTGEMIDVRKLPCTNSSSNGKLAHGGERNidtp 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 226 KHEKIHTGEKPYKCK--ECGKVISSSSSFaKHKRIHTgekpfkclECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFR 303
Cdd:COG5189  339 SRMLKVKDGKPYKCPveGCNKKYKNQNGL-KYHMLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYK 409


                 ....*....
gi 158706490 304 QSANLYVHR 312
Cdd:COG5189  410 NLNGLKYHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 625-704 3.03e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 3.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 625 GEKPYKCE--ECGKAFAPSTDLNQHtkILTGEQSYKCEEcgkafgwSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTT 702
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYH--MLHGHQNQKLHE-------NPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 158706490 703 HR 704
Cdd:COG5189  417 HR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
671-696 3.49e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.49e-04
                          10        20
                  ....*....|....*....|....*.
gi 158706490  671 ALNQHKKIHTGEKPYKCEECGKAFSR 696
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
363-388 3.49e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.49e-04
                          10        20
                  ....*....|....*....|....*.
gi 158706490  363 ALNQHKKIHTGEKPYKCEECGKAFNS 388
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
139-164 3.56e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.56e-04
                          10        20
                  ....*....|....*....|....*.
gi 158706490  139 DLNQHKKIHTGEKPYKCEECGKAFNR 164
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 284-369 4.00e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.94  E-value: 4.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 284 RRIHT-GEKPYTCEV--CGKAFRQSANLYVHRrIHtgekpytcGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGR 360
Cdd:COG5189  340 RMLKVkDGKPYKCPVegCNKKYKNQNGLKYHM-LH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKN 410


                 ....*....
gi 158706490 361 YTALNQHKK 369
Cdd:COG5189  411 LNGLKYHRK 419
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
656-910 1.24e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 656 SYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSR--NLTTHRRVHTREKPYKCEDRGR------------- 720
Cdd:COG5048   33 PDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplELSRHLRTHHNNPSDLNSKSLPlsnskasssslss 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 721 -------------------SFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLN-RHEKIHTGKKPYKCKE---CGKV 777
Cdd:COG5048  113 sssnsndnnllsshslppsSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSNLSlliSSNV 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 778 ITSSSSFAK-HKRIHTGEKPFKCLECGKaFTSSTTLTKHRRIHTGEKPYTCE---------------ECGKAFRQSAILY 841
Cdd:COG5048  193 STSIPSSSEnSPLSSSYSIPSSSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQspsslsssdssssasESPRSSLPTASSQ 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 842 VHRRIHTGE-------KPYTCGECGKTFRQSANLYAHK--KIHTGE--KPYTCG--DCGKTFRQSANLYAHKKIHTGDKT 908
Cdd:COG5048  272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISP 351


                 ..
gi 158706490 909 IQ 910
Cdd:COG5048  352 AK 353
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 355-453 1.32e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.40  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 355 GKAFGRYTALNQHKKihtGEKPYKCE--ECGKAFNSSTNLTAHkRIHTREKPYTCEDRGRafgLSTNLNEYKkihtgDKP 432
Cdd:COG5189  331 GERNIDTPSRMLKVK---DGKPYKCPveGCNKKYKNQNGLKYH-MLHGHQNQKLHENPSP---EKMNIFSAK-----DKP 398

                         90       100
                 ....*....|....*....|.
gi 158706490 433 YKCKECGKAFIHSLHLNKHEK 453
Cdd:COG5189  399 YRCEVCDKRYKNLNGLKYHRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
559-582 1.39e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.39e-03
                          10        20
                  ....*....|....*....|....
gi 158706490  559 NLYVHRRIHTGEKPYKCEECGKAF 582
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 508-589 1.45e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 508 RRIHT-GEKPYTCEV--CGKAFRQSAILYVHRrIHTGEKPYTCEECGKtfrQSANLYVHRrihtgEKPYKCEECGKafgR 584
Cdd:COG5189  340 RMLKVkDGKPYKCPVegCNKKYKNQNGLKYHM-LHGHQNQKLHENPSP---EKMNIFSAK-----DKPYRCEVCDK---R 407


                 ....*
gi 158706490 585 YTDLN 589
Cdd:COG5189  408 YKNLN 412
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 149-229 1.49e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 149 GEKPYKCE--ECGKAFNRSTNLTAHKRI-HNREKAYTGEDRDRAFGWSTNlneykkihtgDKPYKCKECGKAFMHSSHLN 225
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHMLHgHQNQKLHENPSPEKMNIFSAK----------DKPYRCEVCDKRYKNLNGLK 415


                 ....
gi 158706490 226 KHEK 229
Cdd:COG5189  416 YHRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
335-358 2.34e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.34e-03
                          10        20
                  ....*....|....*....|....
gi 158706490  335 NLYVHRRIHTGEKPYKCEDCGKAF 358
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 457-536 2.41e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158706490 457 GKKPYKCK--QCGKVITSSSSFaKHKRIHTgekpfeclECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYV 534
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGL-KYHMLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 158706490 535 HR 536
Cdd:COG5189  417 HR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
783-808 3.94e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.94e-03
                          10        20
                  ....*....|....*....|....*.
gi 158706490  783 SFAKHKRIHTGEKPFKCLECGKAFTS 808
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
812-836 4.06e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.06e-03
                          10        20
                  ....*....|....*....|....*
gi 158706490  812 LTKHRRIHTGEKPYTCEECGKAFRQ 836
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
755-776 4.99e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.99e-03
                          10        20
                  ....*....|....*....|..
gi 158706490  755 HLNRHEKIHTGKKPYKCKECGK 776
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGK 22
zf-H2C2_2 pfam13465
Zinc-finger double domain;
280-304 5.14e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.14e-03
                          10        20
                  ....*....|....*....|....*
gi 158706490  280 LTKHRRIHTGEKPYTCEVCGKAFRQ 304
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
504-528 5.14e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.14e-03
                          10        20
                  ....*....|....*....|....*
gi 158706490  504 LTKHRRIHTGEKPYTCEVCGKAFRQ 528
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
475-500 5.96e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.96e-03
                          10        20
                  ....*....|....*....|....*.
gi 158706490  475 SFAKHKRIHTGEKPFECLECGKAFTS 500
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 741-763 6.22e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 6.22e-03
                          10        20
                  ....*....|....*....|...
gi 158706490  741 YKCKECGKVFKQSSHLNRHEKIH 763
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
307-332 6.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.45e-03
                          10        20
                  ....*....|....*....|....*.
gi 158706490  307 NLYVHRRIHTGEKPYTCGECGKTFRQ 332
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
251-275 6.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.51e-03
                          10        20
                  ....*....|....*....|....*
gi 158706490  251 SFAKHKRIHTGEKPFKCLECGKAFN 275
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
532-556 6.64e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.64e-03
                          10        20
                  ....*....|....*....|....*
gi 158706490  532 LYVHRRIHTGEKPYTCEECGKTFRQ 556
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
223-244 8.24e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 8.24e-03
                          10        20
                  ....*....|....*....|..
gi 158706490  223 HLNKHEKIHTGEKPYKCKECGK 244
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGK 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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