NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|116242627|sp|Q9H1U4|]
View 

RecName: Full=Multiple epidermal growth factor-like domains protein 9; Short=Multiple EGF-like domains protein 9; AltName: Full=Epidermal growth factor-like protein 5; Short=EGF-like protein 5; Flags: Precursor

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 254-301 6.89e-10

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 6.89e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 116242627  254 CDCSPHGALSIPCNSS-GKCQCKVGVIGSICDRCQDGYYGFSKNGCLPC 301
Cdd:pfam00053   1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 204-252 9.10e-10

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.28  E-value: 9.10e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 116242627 204 CNCSVVGSLNvNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL-CQ 252
Cdd:cd00055    2 CDCNGHGSLS-GQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGgCQ 50
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
41-201 2.22e-08

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.17  E-value: 2.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  41 VTGGGGAAGQVDAS-----PGPGLRGEPSH------------------PFPRATAPTAQAPRTGPPRAT--------VHR 89
Cdd:PRK07003 362 VTGGGAPGGGVPARvagavPAPGARAAAAVgasavpavtavtgaagaaLAPKAAAAAAATRAEAPPAAPappatadrGDD 441

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  90 PLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVattvpaptt 169
Cdd:PRK07003 442 AADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARA--------- 512

                        170       180       190
                 ....*....|....*....|....*....|..
gi 116242627 170 prtptpdlPSSSNSSVLPTPPATEAPSSPPPE 201
Cdd:PRK07003 513 --------PAAASREDAPAAAAPPAPEARPPT 536
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 300-346 9.45e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.81  E-value: 9.45e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 116242627 300 PCQCNNRSA---SCDALTGACLnCQENSKGNHCEECKEGFYQSPDATKEC 346
Cdd:cd00055    1 PCDCNGHGSlsgQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 400-441 7.02e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 40.41  E-value: 7.02e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 116242627  400 CQCHGHVDPVKTpkiCKPESGECInCLHNTTGFWCENCLEGY 441
Cdd:pfam00053   1 CDCNPHGSLSDT---CDPETGQCL-CKPGVTGRHCDRCKPGY 38
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 373-401 2.94e-03

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 36.18  E-value: 2.94e-03
                         10        20
                 ....*....|....*....|....*....
gi 116242627 373 QCKDGYIGPNCNKCENGYYNFDSICRKCQ 401
Cdd:cd00055   22 ECKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
 
Name Accession Description Interval E-value
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 254-301 6.89e-10

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 6.89e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 116242627  254 CDCSPHGALSIPCNSS-GKCQCKVGVIGSICDRCQDGYYGFSKNGCLPC 301
Cdd:pfam00053   1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 204-252 9.10e-10

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.28  E-value: 9.10e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 116242627 204 CNCSVVGSLNvNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL-CQ 252
Cdd:cd00055    2 CDCNGHGSLS-GQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGgCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
204-243 9.13e-10

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 54.24  E-value: 9.13e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 116242627   204 CNCSVVGSLNvNRCNQTTGQCECRPGYQGLHCETCKEGFY 243
Cdd:smart00180   1 CDCDPGGSAS-GTCDPDTGQCECKPNVTGRRCDRCAPGYY 39
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 253-297 9.46e-10

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.28  E-value: 9.46e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 116242627 253 PCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSKNG 297
Cdd:cd00055    1 PCDCNGHGSLSGQCDPgTGQCECKPNTTGRRCDRCAPGYYGLPSQG 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 204-256 1.65e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 53.51  E-value: 1.65e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 116242627  204 CNCSVVGSLNvNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTsglCQPCDC 256
Cdd:pfam00053   1 CDCNPHGSLS-DTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPS---DPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
254-298 1.74e-09

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 53.47  E-value: 1.74e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 116242627   254 CDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSKNGC 298
Cdd:smart00180   1 CDCDPGGSASGTCDPdTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
41-201 2.22e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.17  E-value: 2.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  41 VTGGGGAAGQVDAS-----PGPGLRGEPSH------------------PFPRATAPTAQAPRTGPPRAT--------VHR 89
Cdd:PRK07003 362 VTGGGAPGGGVPARvagavPAPGARAAAAVgasavpavtavtgaagaaLAPKAAAAAAATRAEAPPAAPappatadrGDD 441

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  90 PLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVattvpaptt 169
Cdd:PRK07003 442 AADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARA--------- 512

                        170       180       190
                 ....*....|....*....|....*....|..
gi 116242627 170 prtptpdlPSSSNSSVLPTPPATEAPSSPPPE 201
Cdd:PRK07003 513 --------PAAASREDAPAAAAPPAPEARPPT 536
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 300-346 9.45e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.81  E-value: 9.45e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 116242627 300 PCQCNNRSA---SCDALTGACLnCQENSKGNHCEECKEGFYQSPDATKEC 346
Cdd:cd00055    1 PCDCNGHGSlsgQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 301-340 6.70e-06

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.50  E-value: 6.70e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 116242627  301 CQCNNR---SASCDALTGACLnCQENSKGNHCEECKEGFYQSP 340
Cdd:pfam00053   1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLP 42
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 400-441 7.02e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 40.41  E-value: 7.02e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 116242627  400 CQCHGHVDPVKTpkiCKPESGECInCLHNTTGFWCENCLEGY 441
Cdd:pfam00053   1 CDCNPHGSLSDT---CDPETGQCL-CKPGVTGRHCDRCKPGY 38
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
301-340 1.70e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 39.22  E-value: 1.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 116242627   301 CQCN---NRSASCDALTGACLnCQENSKGNHCEECKEGFYQSP 340
Cdd:smart00180   1 CDCDpggSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDG 42
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 68-141 1.75e-04

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 44.12  E-value: 1.75e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116242627   68 PRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLwATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPT 141
Cdd:TIGR00601  77 PKTGTGKVAPPAATPTSAPTPTPSPPASPASGMSAAPA-SAVEEKSPSEESATATAPESPSTSVPSSGSDAAST 149
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 400-444 4.80e-04

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 38.10  E-value: 4.80e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 116242627 400 CQCHGHVDPvktPKICKPESGECInCLHNTTGFWCENCLEGYVHD 444
Cdd:cd00055    2 CDCNGHGSL---SGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGL 42
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 64-200 6.72e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 42.83  E-value: 6.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   64 SHPFPRATAPTAQ---APRTGPPRATVHRPLAATSpAQSPETTPLwaTAGPSSTTFQ----APLGPSPTTPPAAERTSTT 136
Cdd:pfam03154 410 AHPPPLQLMPQSQqlpPPPAQPPVLTQSQSLPPPA-ASHPPTSGL--HQVPSQSPFPqhpfVPGGPPPITPPSGPPTSTS 486

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  137 SQAPTRPAPTTLSTTTGPApttpvattvpapttprtptpdLPSSSNSSVLPT------PPATEAPSSPPP 200
Cdd:pfam03154 487 SAMPGIQPPSSASVSSSGP---------------------VPAAVSCPLPPVqikeeaLDEAEEPESPPP 535
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 64-150 2.33e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 40.60  E-value: 2.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  64 SHPFPRATAPTAQAPRTGPPRATVhRPLAATSPAQSPETTPlwaTAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRP 143
Cdd:COG3266  263 SASAPATTSLGEQQEVSLPPAVAA-QPAAAAAAQPSAVALP---AAPAAAAAAAAPAEAAAPQPTAAKPVVTETAAPAAP 338


                 ....*..
gi 116242627 144 APTTLST 150
Cdd:COG3266  339 APEAAAA 345
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 373-401 2.94e-03

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 36.18  E-value: 2.94e-03
                         10        20
                 ....*....|....*....|....*....
gi 116242627 373 QCKDGYIGPNCNKCENGYYNFDSICRKCQ 401
Cdd:cd00055   22 ECKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 41-147 5.07e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.37  E-value: 5.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  41 VTGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPL 120
Cdd:NF040712 200 ATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGE 279

                         90       100
                 ....*....|....*....|....*..
gi 116242627 121 GPSPTTPPAAERTSTTSQAPTRPAPTT 147
Cdd:NF040712 280 PPAPGAAETPEAAEPPAPAPAAPAAPA 306
 
Name Accession Description Interval E-value
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 254-301 6.89e-10

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 54.67  E-value: 6.89e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 116242627  254 CDCSPHGALSIPCNSS-GKCQCKVGVIGSICDRCQDGYYGFSKNGCLPC 301
Cdd:pfam00053   1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 204-252 9.10e-10

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.28  E-value: 9.10e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 116242627 204 CNCSVVGSLNvNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL-CQ 252
Cdd:cd00055    2 CDCNGHGSLS-GQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGgCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
204-243 9.13e-10

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 54.24  E-value: 9.13e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 116242627   204 CNCSVVGSLNvNRCNQTTGQCECRPGYQGLHCETCKEGFY 243
Cdd:smart00180   1 CDCDPGGSAS-GTCDPDTGQCECKPNVTGRRCDRCAPGYY 39
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 253-297 9.46e-10

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.28  E-value: 9.46e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 116242627 253 PCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSKNG 297
Cdd:cd00055    1 PCDCNGHGSLSGQCDPgTGQCECKPNTTGRRCDRCAPGYYGLPSQG 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 204-256 1.65e-09

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 53.51  E-value: 1.65e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 116242627  204 CNCSVVGSLNvNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTsglCQPCDC 256
Cdd:pfam00053   1 CDCNPHGSLS-DTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPS---DPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
254-298 1.74e-09

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 53.47  E-value: 1.74e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 116242627   254 CDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSKNGC 298
Cdd:smart00180   1 CDCDPGGSASGTCDPdTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
41-201 2.22e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.17  E-value: 2.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  41 VTGGGGAAGQVDAS-----PGPGLRGEPSH------------------PFPRATAPTAQAPRTGPPRAT--------VHR 89
Cdd:PRK07003 362 VTGGGAPGGGVPARvagavPAPGARAAAAVgasavpavtavtgaagaaLAPKAAAAAAATRAEAPPAAPappatadrGDD 441

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  90 PLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVattvpaptt 169
Cdd:PRK07003 442 AADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARA--------- 512

                        170       180       190
                 ....*....|....*....|....*....|..
gi 116242627 170 prtptpdlPSSSNSSVLPTPPATEAPSSPPPE 201
Cdd:PRK07003 513 --------PAAASREDAPAAAAPPAPEARPPT 536
PHA03247 PHA03247
large tegument protein UL36; Provisional
 47-209 9.69e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.33  E-value: 9.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   47 AAGQVDASPGPGLRGEPSHPFPRATAPTAQAPrTGPPRATVHRPLAATSPAQSPETTPLWATAGPSS-TTFQAPLGPSPT 125
Cdd:PHA03247 2691 TVGSLTSLADPPPPPPTPEPAPHALVSATPLP-PGPAAARQASPALPAAPAPPAVPAGPATPGGPARpARPPTTAGPPAP 2769

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  126 TPPAAeRTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDlPSSSNSSVLPTPP-----ATEAPSSPPP 200
Cdd:PHA03247 2770 APPAA-PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP-PAASPAGPLPPPTsaqptAPPPPPGPPP 2847


                  ....*....
gi 116242627  201 EYVCNCSVV 209
Cdd:PHA03247 2848 PSLPLGGSV 2856
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 39-147 1.64e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.61  E-value: 1.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  39 GNVTGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLW------ATAGPS 112
Cdd:PRK07764 384 RLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGgapsppPAAAPS 463

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 116242627 113 STTFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTT 147
Cdd:PRK07764 464 AQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPA 498
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 300-346 9.45e-07

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 45.81  E-value: 9.45e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 116242627 300 PCQCNNRSA---SCDALTGACLnCQENSKGNHCEECKEGFYQSPDATKEC 346
Cdd:cd00055    1 PCDCNGHGSlsgQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGC 49
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
47-203 6.55e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 49.10  E-value: 6.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  47 AAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRAtvhrPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTT 126
Cdd:PRK12323 409 APAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA----PAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAA 484

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116242627 127 PPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPPPEYV 203
Cdd:PRK12323 485 PAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV 561
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 301-340 6.70e-06

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.50  E-value: 6.70e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 116242627  301 CQCNNR---SASCDALTGACLnCQENSKGNHCEECKEGFYQSP 340
Cdd:pfam00053   1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLP 42
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 42-149 1.26e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 48.14  E-value: 1.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  42 TGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVhRPlAATSPAQSPETTPLWATAGPSSTTFQAPLG 121
Cdd:PRK14959 374 SGGGASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSA-AP-ATPAPSAAPSPRVPWDDAPPAPPRSGIPPR 451

                         90       100
                 ....*....|....*....|....*...
gi 116242627 122 PSPTTPpaaertsTTSQAPTRPAPTTLS 149
Cdd:PRK14959 452 PAPRMP-------EASPVPGAPDSVASA 472
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 44-145 1.28e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.44  E-value: 1.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  44 GGGAAGQVDASPGPGLRGEPShpfPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPS 123
Cdd:PRK07764 404 AAPAAAPAPAAAAPAAAAAPA---PAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAP 480

                         90       100
                 ....*....|....*....|..
gi 116242627 124 PTTPPAAERTSTTSQAPTRPAP 145
Cdd:PRK07764 481 APAPPAAPAPAAAPAAPAAPAA 502
PHA03247 PHA03247
large tegument protein UL36; Provisional
 44-200 2.16e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   44 GGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSP----------AQSPETTPLWATAGPSS 113
Cdd:PHA03247 2747 GPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPspwdpadppaAVLAPAAALPPAASPAG 2826

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  114 T----TFQAPLGPSPTTPPAAERTST----------TSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPS 179
Cdd:PHA03247 2827 PlpppTSAQPTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPE 2906

                         170       180
                  ....*....|....*....|.
gi 116242627  180 SSNSSVLPTPPATEAPSSPPP 200
Cdd:PHA03247 2907 RPPQPQAPPPPQPQPQPPPPP 2927
PRK13042 PRK13042
superantigen-like protein SSL4; Reviewed;
71-145 2.20e-05

superantigen-like protein SSL4; Reviewed;


Pssm-ID: 183854 [Multi-domain]  Cd Length: 291  Bit Score: 46.55  E-value: 2.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  71 TAPTAQAPRTGPPRATVHRPLAaTSPA---QSPETTPLWATagPSSTTFQAPLG-PSPTTPPAAE----RTSTTSQAPTR 142
Cdd:PRK13042  22 TTTTQAANATTPSSTKVEAPQS-TPPStkvEAPQSKPNATT--PPSTKVEAPQQtPNATTPSSTKvetpQSPTTKQVPTE 98


                 ...
gi 116242627 143 PAP 145
Cdd:PRK13042  99 INP 101
PHA03247 PHA03247
large tegument protein UL36; Provisional
 53-200 4.01e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 4.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   53 ASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRP----------LAATSPAQSPETTPLWATAGPSSTTFQAPLGP 122
Cdd:PHA03247 2838 APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPaaparppvrrLARPAVSRSTESFALPPDQPERPPQPQAPPPP 2917

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  123 SPT-TPPAAERTSTTSQAPTRP----APTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPpateAPSS 197
Cdd:PHA03247 2918 QPQpQPPPPPQPQPPPPPPPRPqpplAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAP----ASST 2993


                  ...
gi 116242627  198 PPP 200
Cdd:PHA03247 2994 PPL 2996
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 42-200 6.30e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 6.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   42 TGGGGAAGQVDASPGP--------GLRGEPSH-PFPRATAPTAQAPRTGPPRATVHRPLAAtSPAQSPETT-----PLWA 107
Cdd:PHA03307  113 SPDPPPPTPPPASPPPspapdlseMLRPVGSPgPPPAASPPAAGASPAAVASDAASSRQAA-LPLSSPEETarapsSPPA 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  108 TAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTR----PAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNS 183
Cdd:PHA03307  192 EPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRsaadDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWE 271

                         170
                  ....*....|....*..
gi 116242627  184 SVLPTPPATEAPSSPPP 200
Cdd:PHA03307  272 ASGWNGPSSRPGPASSS 288
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 42-201 6.95e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 6.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  42 TGGGGAAGQVDASPG--PGLRGEPSHPFPRATAPTAQAPR----TGPPRATVHRPLAATSPAQ-SPETTPLWATAGPSST 114
Cdd:PRK07764 616 AAPAAPAAPAAPAPAgaAAAPAEASAAPAPGVAAPEHHPKhvavPDASDGGDGWPAKAGGAAPaAPPPAPAPAAPAAPAG 695

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627 115 TFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEA 194
Cdd:PRK07764 696 AAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775


                 ....*..
gi 116242627 195 PSSPPPE 201
Cdd:PRK07764 776 PSPPSEE 782
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 400-441 7.02e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 40.41  E-value: 7.02e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 116242627  400 CQCHGHVDPVKTpkiCKPESGECInCLHNTTGFWCENCLEGY 441
Cdd:pfam00053   1 CDCNPHGSLSDT---CDPETGQCL-CKPGVTGRHCDRCKPGY 38
PHA03247 PHA03247
large tegument protein UL36; Provisional
 39-200 7.40e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 7.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   39 GNVTGGGGAAG-----QVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATS-------PAQSPETTP-- 104
Cdd:PHA03247 2635 ANEPDPHPPPTvpppeRPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTsladpppPPPTPEPAPha 2714

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  105 ----LWATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSS 180
Cdd:PHA03247 2715 lvsaTPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSES 2794

                         170       180
                  ....*....|....*....|
gi 116242627  181 SNSSVLPTPPATEAPSSPPP 200
Cdd:PHA03247 2795 RESLPSPWDPADPPAAVLAP 2814
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 41-202 9.14e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 9.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  41 VTGGGGAAGQVDASPGPGLRGEPShPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWAT------------ 108
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPE-EAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHpkhvavpdasdg 665

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627 109 --AGPSSTTFQAPLGPSPTTPPAAERTStTSQAPTRPAPTtlsttTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVL 186
Cdd:PRK07764 666 gdGWPAKAGGAAPAAPPPAPAPAAPAAP-AGAAPAQPAPA-----PAATPPAGQADDPAAQPPQAAQGASAPSPAADDPV 739

                        170
                 ....*....|....*.
gi 116242627 187 PTPPATEAPSSPPPEY 202
Cdd:PRK07764 740 PLPPEPDDPPDPAGAP 755
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 43-147 1.08e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 45.09  E-value: 1.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  43 GGGGAAGQVDASPGPGLRGEPShPFPRATAPTAQAPRTGPPRATVH--RPLAATSPAQSPETTPLWATAGPSSTTFQAPL 120
Cdd:PRK14951 369 AAEAAAPAEKKTPARPEAAAPA-AAPVAQAAAAPAPAAAPAAAASApaAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVAL 447

                         90       100
                 ....*....|....*....|....*..
gi 116242627 121 GPSPTTPPAAERTSTTSQAPTRPAPTT 147
Cdd:PRK14951 448 APAPPAQAAPETVAIPVRVAPEPAVAS 474
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
301-340 1.70e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 39.22  E-value: 1.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 116242627   301 CQCN---NRSASCDALTGACLnCQENSKGNHCEECKEGFYQSP 340
Cdd:smart00180   1 CDCDpggSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDG 42
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 46-201 1.72e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.78  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   46 GAAGQVDASPGPGLRGEPSHPFPRATAPtaqAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTfqAPLGPSPT 125
Cdd:PHA03307   55 VVAGAAACDRFEPPTGPPPGPGTEAPAN---ESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTP--PPASPPPS 129

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116242627  126 TPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTvpapttprtptpdlPSSSNSSVLPTPPATEAPSSPPPE 201
Cdd:PHA03307  130 PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAA--------------SSRQAALPLSSPEETARAPSSPPA 191
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 68-141 1.75e-04

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 44.12  E-value: 1.75e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116242627   68 PRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLwATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPT 141
Cdd:TIGR00601  77 PKTGTGKVAPPAATPTSAPTPTPSPPASPASGMSAAPA-SAVEEKSPSEESATATAPESPSTSVPSSGSDAAST 149
PHA03247 PHA03247
large tegument protein UL36; Provisional
 57-200 2.02e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 2.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   57 PGLRGEPSHPFPRATAPTAQAPRTGPPRAtvhrPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPS------PTTPPAA 130
Cdd:PHA03247 2598 PRAPVDDRGDPRGPAPPSPLPPDTHAPDP----PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRvsrprrARRLGRA 2673

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 116242627  131 ERTSTTSQAPTRPA--PTTLSTTTGPAPTTPVATTVPAPTTPRTPTPdLPSSSNSSVLPTPPATEAPSSPPP 200
Cdd:PHA03247 2674 AQASSPPQRPRRRAarPTVGSLTSLADPPPPPPTPEPAPHALVSATP-LPPGPAAARQASPALPAAPAPPAV 2744
PHA03247 PHA03247
large tegument protein UL36; Provisional
 55-200 3.09e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 3.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   55 PGPGLRGEPSHPFPRATAPTAQAPR----TGPPRATVHR-------PLAATSPAQSPETTPLWATAGPSSTTFQaplgPS 123
Cdd:PHA03247 2627 PPPSPSPAANEPDPHPPPTVPPPERprddPAPGRVSRPRrarrlgrAAQASSPPQRPRRRAARPTVGSLTSLAD----PP 2702

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 116242627  124 PTTPPAAER-TSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPPP 200
Cdd:PHA03247 2703 PPPPTPEPApHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPP 2780
PHA03247 PHA03247
large tegument protein UL36; Provisional
 45-145 3.20e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 3.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   45 GGAAGQVDASPGPGLRGEPSHPFPRATAPTAQaPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSP 124
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTT 2947

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 116242627  125 TTPPAAE---------------------RTSTTSQAPTRPAP 145
Cdd:PHA03247 2948 DPAGAGEpsgavpqpwlgalvpgrvavpRFRVPQPAPSREAP 2989
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 400-444 4.80e-04

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 38.10  E-value: 4.80e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 116242627 400 CQCHGHVDPvktPKICKPESGECInCLHNTTGFWCENCLEGYVHD 444
Cdd:cd00055    2 CDCNGHGSL---SGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGL 42
PHA03247 PHA03247
large tegument protein UL36; Provisional
 44-201 5.65e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 5.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   44 GGGAAGQVDASPGPGLRGEPSHPFPRATA--PTAQAPRTGPPRATVHRPLA-ATSPAQSPETTPLWATAGPSSTTFQAPL 120
Cdd:PHA03247 2788 VASLSESRESLPSPWDPADPPAAVLAPAAalPPAASPAGPLPPPTSAQPTApPPPPGPPPPSLPLGGSVAPGGDVRRRPP 2867

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  121 GPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPPP 200
Cdd:PHA03247 2868 SRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTT 2947


                  .
gi 116242627  201 E 201
Cdd:PHA03247 2948 D 2948
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 64-200 6.72e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 42.83  E-value: 6.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   64 SHPFPRATAPTAQ---APRTGPPRATVHRPLAATSpAQSPETTPLwaTAGPSSTTFQ----APLGPSPTTPPAAERTSTT 136
Cdd:pfam03154 410 AHPPPLQLMPQSQqlpPPPAQPPVLTQSQSLPPPA-ASHPPTSGL--HQVPSQSPFPqhpfVPGGPPPITPPSGPPTSTS 486

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  137 SQAPTRPAPTTLSTTTGPApttpvattvpapttprtptpdLPSSSNSSVLPT------PPATEAPSSPPP 200
Cdd:pfam03154 487 SAMPGIQPPSSASVSSSGP---------------------VPAAVSCPLPPVqikeeaLDEAEEPESPPP 535
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
47-146 1.15e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.79  E-value: 1.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  47 AAGQVDASPGPGLRGEPSHPFPRATAPTAQ---APRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPS 123
Cdd:PRK12323 459 AAAARPAAAGPRPVAAAAAAAPARAAPAAApapADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAF 538

                         90       100
                 ....*....|....*....|....*.
gi 116242627 124 PT---TPPAAERTSTTSQAPTRPAPT 146
Cdd:PRK12323 539 ETlapAPAAAPAPRAAAATEPVVAPR 564
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 66-146 1.19e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 41.72  E-value: 1.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  66 PFPRATAPTAQAPRTG-PPRATVHRPLAAtSPAQSPETTPLWATAGPSSTTFQAPLGPSPTTPPAAErTSTTSQAPTRPA 144
Cdd:PRK14950 364 PAPQPAKPTAAAPSPVrPTPAPSTRPKAA-AAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAP-KLTRAAIPVDEK 441


                 ..
gi 116242627 145 PT 146
Cdd:PRK14950 442 PK 443
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 42-202 1.37e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.45  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  42 TGGGGAAGQVDASPGPGlrgEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATS------PAQSPETTPLWATAGPSSTT 115
Cdd:PLN03209 392 SSSPASSKSVDAVAKPA---EPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYAryedlkPPTSPSPTAPTGVSPSVSST 468

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627 116 FQAPLgpSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEA- 194
Cdd:PLN03209 469 SSVPA--VPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQh 546

                        170
                 ....*....|....*
gi 116242627 195 -------PSSPPPEY 202
Cdd:PLN03209 547 haqpkprPLSPYTMY 561
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 47-135 1.94e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 1.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  47 AAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTP-LWATAGPSSTT----FQAPLG 121
Cdd:PRK14951 398 AAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAaPETVAIPVRVApepaVASAAP 477

                         90
                 ....*....|....
gi 116242627 122 PSPTTPPAAERTST 135
Cdd:PRK14951 478 APAAAPAAARLTPT 491
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 64-150 2.33e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 40.60  E-value: 2.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  64 SHPFPRATAPTAQAPRTGPPRATVhRPLAATSPAQSPETTPlwaTAGPSSTTFQAPLGPSPTTPPAAERTSTTSQAPTRP 143
Cdd:COG3266  263 SASAPATTSLGEQQEVSLPPAVAA-QPAAAAAAQPSAVALP---AAPAAAAAAAAPAEAAAPQPTAAKPVVTETAAPAAP 338


                 ....*..
gi 116242627 144 APTTLST 150
Cdd:COG3266  339 APEAAAA 345
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 49-143 2.68e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 40.70  E-value: 2.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  49 GQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVhRPLAATSPAQSPettplwataGPSSttfQAPLGPSPTTPP 128
Cdd:PRK14954 378 GGVAPSPAGSPDVKKKAPEPDLPQPDRHPGPAKPEAPGA-RPAELPSPASAP---------TPEQ---QPPVARSAPLPP 444

                         90
                 ....*....|....*
gi 116242627 129 AAERTSTTSQAPTRP 143
Cdd:PRK14954 445 SPQASAPRNVASGKP 459
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 39-148 2.80e-03

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 40.84  E-value: 2.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  39 GNVTGGGGAAGQVdaspgPGLRGEPSHPFPRATAP-TAQAPRTGPPRATVHRPLAATSPAQSPETTPlwatagPSSTtfq 117
Cdd:PLN02217 560 GLFAGNPGSTNST-----PTGSAASSNTTFSSDSPsTVVAPSTSPPAGHLGSPPATPSKIVSPSTSP------PASH--- 625

                         90       100       110
                 ....*....|....*....|....*....|.
gi 116242627 118 apLGPSPTTPPAAERTSTTSQAPTRPAPTTL 148
Cdd:PLN02217 626 --LGSPSTTPSSPESSIKVASTETASPESSI 654
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 41-134 2.82e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.56  E-value: 2.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  41 VTGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTtfqAPL 120
Cdd:PRK14950 367 QPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPVDE---KPK 443

                         90
                 ....*....|....
gi 116242627 121 GPSPTTPPAAERTS 134
Cdd:PRK14950 444 YTPPAPPKEEEKAL 457
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 373-401 2.94e-03

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 36.18  E-value: 2.94e-03
                         10        20
                 ....*....|....*....|....*....
gi 116242627 373 QCKDGYIGPNCNKCENGYYNFDSICRKCQ 401
Cdd:cd00055   22 ECKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
PHA03247 PHA03247
large tegument protein UL36; Provisional
 52-200 3.09e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 3.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   52 DASPG-PGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTP-------LWA-TAGPSSTTFQAPLGP 122
Cdd:PHA03247 2472 ELFPGaPVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVgepvhprMLTwIRGLEELASDDAGDP 2551

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116242627  123 SPTTPPAAERTSTTSQAPT-RPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVlPTPPATEAPSSPPP 200
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPpRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPS-PLPPDTHAPDPPPP 2629
motB PRK12799
flagellar motor protein MotB; Reviewed
 51-147 3.17e-03

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 40.08  E-value: 3.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  51 VDASPgPGLRGEPSHPFPRATAPTAQ-----APRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPT 125
Cdd:PRK12799 301 VAAVT-PSSAVTQSSAITPSSAAIPSpavipSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQPQPM 379

                         90       100
                 ....*....|....*....|..
gi 116242627 126 TPPAAERTSTTSQAPTRPAPTT 147
Cdd:PRK12799 380 STTETQQSSTGNITSTANGPTT 401
flhF PRK06995
flagellar biosynthesis protein FlhF;
52-149 3.77e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 39.95  E-value: 3.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  52 DASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAA------TSPAQSPETTPLWATAGPSSTTFQAPLGPSPT 125
Cdd:PRK06995  55 AAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAKRLTAqreqlvARAAAPAAPEAQAPAAPAERAAAENAARRLAR 134

                         90       100
                 ....*....|....*....|....
gi 116242627 126 TPPAAERTSTTSQAPTRPAPTTLS 149
Cdd:PRK06995 135 AAAAAPRPRVPADAAAAVADAVKA 158
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
43-200 4.25e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.24  E-value: 4.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  43 GGGGaagqvDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPlwATAGPSSTTFQAPLGP 122
Cdd:PRK12323 367 QSGG-----GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAP--ARRSPAPEALAAARQA 439

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 116242627 123 SPTTPPAAertsttSQAPTRPAPTtlstttgpapttPVATTVPAPTTPRTPTPDLPSSSNSSVlPTPPATEAPSSPPP 200
Cdd:PRK12323 440 SARGPGGA------PAPAPAPAAA------------PAAAARPAAAGPRPVAAAAAAAPARAA-PAAAPAPADDDPPP 498
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
70-199 4.71e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 4.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  70 ATAPTAQAPRTGPPRAtVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPlGPSPTTPPAAERTSTTSQAPTRPAPTTLS 149
Cdd:PRK12323 362 AFRPGQSGGGAGPATA-AAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAP-AAAAAARAVAAAPARRSPAPEALAAARQA 439

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 116242627 150 TTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPP 199
Cdd:PRK12323 440 SARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAP 489
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 41-147 5.07e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.37  E-value: 5.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  41 VTGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPL 120
Cdd:NF040712 200 ATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGE 279

                         90       100
                 ....*....|....*....|....*..
gi 116242627 121 GPSPTTPPAAERTSTTSQAPTRPAPTT 147
Cdd:NF040712 280 PPAPGAAETPEAAEPPAPAPAAPAAPA 306
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 66-202 6.39e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 39.69  E-value: 6.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  66 PFPRATAPTAQAPRTGPPRATVHRPLAATSPA--QSPETTPLWATAGPSSTTfqaplgPSPTTPPAAERTSTTSQAPTrP 143
Cdd:PRK08691 394 PQPRPEAETAQTPVQTASAAAMPSEGKTAGPVsnQENNDVPPWEDAPDEAQT------AAGTAQTSAKSIQTASEAET-P 466

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 116242627 144 APTTLSTTTGPAPTTPVATTVPAPTTPRtptpdLPSSSNSSVLPTPPATEAPSSPPPEY 202
Cdd:PRK08691 467 PENQVSKNKAADNETDAPLSEVPSENPI-----QATPNDEAVETETFAHEAPAEPFYGY 520
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 39-147 7.37e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 39.06  E-value: 7.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  39 GNVTGGGGAAGQVDASPGPGLRGEPSHPfPRATAPTAQAPRTGPPRATVHRPLAATSPAQspettplwATAGPSSTTFQA 118
Cdd:COG3266  264 ASAPATTSLGEQQEVSLPPAVAAQPAAA-AAAQPSAVALPAAPAAAAAAAAPAEAAAPQP--------TAAKPVVTETAA 334

                         90       100
                 ....*....|....*....|....*....
gi 116242627 119 PLGPSPTTPPAAertsttsQAPTRPAPTT 147
Cdd:COG3266  335 PAAPAPEAAAAA-------AAPAAPAVAK 356
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 47-200 8.26e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.38  E-value: 8.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   47 AAGQVDASPGPGLRGEPSHPFPRATAPTAQAPRTG-PPRATVHRPlaatSPAQSPETTPLWATAGPSSTTFQAPLGPSPT 125
Cdd:PHA03307  214 SASASSPAPAPGRSAADDAGASSSDSSSSESSGCGwGPENECPLP----RPAPITLPTRIWEASGWNGPSSRPGPASSSS 289

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116242627  126 TPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPPP 200
Cdd:PHA03307  290 SPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSS 364
PHA03378 PHA03378
EBNA-3B; Provisional
 57-148 9.09e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 39.28  E-value: 9.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627  57 PGLRGEPSHPFPRATAPTAQAPRTGPPRAT---VHRPLAATSPAQSPETTPL-----WATAGPSSTTFQAPLGPSPTTPP 128
Cdd:PHA03378 701 PTPMRPPAAPPGRAQRPAAATGRARPPAAApgrARPPAAAPGRARPPAAAPGrarppAAAPGRARPPAAAPGAPTPQPPP 780

                         90       100
                 ....*....|....*....|....*..
gi 116242627 129 AA-------ERTSTTSQAPTRPAPTTL 148
Cdd:PHA03378 781 QAppapqqrPRGAPTPQPPPQAGPTSM 807
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 52-200 9.55e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.00  E-value: 9.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242627   52 DASPGPGLRGEPSHPFPRATAPTAQAPRTGPPR---ATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTT-- 126
Cdd:PHA03307  107 TPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRpvgSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARap 186

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116242627  127 -PPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPPP 200
Cdd:PHA03307  187 sSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPA 261
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH