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Conserved domains on  [gi|28380084|sp|Q9JL19|]
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RecName: Full=Nuclear receptor coactivator 6; AltName: Full=Activating signal cointegrator 2; Short=ASC-2; AltName: Full=Amplified in breast cancer protein 3; AltName: Full=Cancer-amplified transcriptional coactivator ASC-2; AltName: Full=Nuclear receptor coactivator RAP250; Short=NRC; AltName: Full=Nuclear receptor-activating protein, 250 kDa; AltName: Full=Peroxisome proliferator-activated receptor-interacting protein; Short=PPAR-interacting protein; AltName: Full=Thyroid hormone receptor-binding protein

Protein Classification

Nucleic_acid_bd and Med15 domain-containing protein( domain architecture ID 12155422)

protein containing domains Nucleic_acid_bd, Med15, and PHA03247

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Nucleic_acid_bd pfam13820
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ...
 48-189 1.08e-57

Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.


:

Pssm-ID: 463988  Cd Length: 143  Bit Score: 196.11  E-value: 1.08e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084     48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLWILAQSNNQQLRDLGILSV 127
Cdd:pfam13820    1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28380084    128 QIEGEGAINLALG---QNRSQDVRMnGPVASGNSVRMEAGFPMASGPGLIRMTSPAAVMTPQGGN 189
Cdd:pfam13820   79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLISDALPLHLRLAESGE 142
Med15 super family cl26621
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 385-807 6.30e-11

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


The actual alignment was detected with superfamily member pfam09606:

Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 67.73  E-value: 6.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    385 QQASQAHTNFPQMSNPGQFTAPQMKGLQGGPSRVPTPlqqPHLTNKSPASSPSSFQQGSPAssptVNQTQQQMGPRPPQN 464
Cdd:pfam09606   60 QQQPQGGQGNGGMGGGQQGMPDPINALQNLAGQGTRP---QMMGPMGPGPGGPMGQQMGGP----GTASNLLASLGRPQM 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    465 NPLSQGFQQPVSSPGRnpmVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPnfMQGQVPSTTAAt 544
Cdd:pfam09606  133 PMGGAGFPSQMSRVGR---MQPGGQAGGMMQPSSGQPGSGTPNQMGPNGGPGQGQAGGMNGGQQGP--MGGQMPPQMGV- 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    545 PGNSGALQLQaNQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN-----INNQQAGSSGVPQVTLGNMQGQPQQ 619
Cdd:pfam09606  207 PGMPGPADAG-AQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSqlgmgINQMQQMPQGVGGGAGQGGPGQPMG 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    620 GPPSQLMGMHQQIVPSQGQMAQQQGTLNPQNPMILSRAQLMPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQQGPQMMAPh 699
Cdd:pfam09606  286 PPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANP- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    700 nqmMGPQGQVLLQQNPMIEQIMTNQMQGNKAQFNSQNQSNVMP------GPAQIMRGPTPNmQGNMVQFTGQMSGQMLPQ 773
Cdd:pfam09606  365 ---MQRGQPGMMSSPSPVPGQQVRQVTPNQFMRQSPQPSVPSPqgpgsqPPQSHPGGMIPS-PALIPSPSPQMSQQPAQQ 440

                          410       420       430
                   ....*....|....*....|....*....|....
gi 28380084    774 QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHTD 807
Cdd:pfam09606  441 RTIGQDSPGGSLNTPGQSAVNSPLNPQEEQLYRE 474
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 1171-1808 2.46e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1171 PGPSPLSATQGATPQQP-PVNSLPSSHGH-HFPNvaAPTQTSRPKTP--------NRASPRPYYPQTPNNRPPSTEPSEI 1240
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPaPRPSEPAVTSRaRRPD--APPQSARPRAPvddrgdprGPAPPSPLPPDTHAPDPPPPSPSPA 2634

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1241 SLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPttlkaigQAPSNLTITNPPnfAAPQAhkldsvVVNSGKQS 1320
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAA-------QASSPPQRPRRR--AARPT------VGSLTSLA 2699

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1321 NPGTTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTSTTMLQnmelprnVLVGPTPLANPPLPGSFPNNTGl 1400
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA-------TPGGPARPARPPTTAGPPAPAP- 2771

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1401 nPQNPTVPVPAMGTVlednkesvnipqdsdcqnaqgrkeqvnteLKVVPTQEAKMAVPEDQSKKDGQPLDPNKLPSVEEN 1480
Cdd:PHA03247 2772 -PAAPAAGPPRRLTR-----------------------------PAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1481 KnlmSPAMREAPTSLSQlldnsGAPNVTIKPPGLTDLEVTPPVVSGEDLRKAsviptlqdPPSKEPSTSLSSPHSSePCS 1560
Cdd:PHA03247 2822 A---SPAGPLPPPTSAQ-----PTAPPPPPGPPPPSLPLGGSVAPGGDVRRR--------PPSRSPAAKPAAPARP-PVR 2884

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1561 TLARSELS-EVSSNAAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSSNTSAALPTHLQSALMSTVVTMPNVGN 1639
Cdd:PHA03247 2885 RLARPAVSrSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWL 2964

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1640 KVMVSeGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPS-TIPATPLTTNSGLMPPSVAVVGPLHIPQNIKFSSApvTP 1718
Cdd:PHA03247 2965 GALVP-GRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRvSSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDA--DS 3041

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1719 NVPSSSPAPNIQTGRPLvlssratpvqlpSPPCTSSPVVAPNPsvqqvkelNPDEASPQTNTSAdQSTLPPSQPTTVVSS 1798
Cdd:PHA03247 3042 LFDSDSERSDLEALDPL------------PPEPHDPFAHEPDP--------ATPEAGARESPSS-QFGPPPLSANAALSR 3100

                         650
                  ....*....|
gi 28380084  1799 LLTNSPGSSA 1808
Cdd:PHA03247 3101 RYVRSTGRSA 3110
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 1059-1280 1.62e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1059 PPRGPLNPDSQRMPVQQSgnVPVMVGLQGPASVPPSPDKQRMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPEA 1138
Cdd:PHA03247 2744 VPAGPATPGGPARPARPP--TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1139 ---SGSEVPSVAGGPNNMPSHLVVSQNQLMMTG--------PKPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1207
Cdd:PHA03247 2822 aspAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGsvapggdvRRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28380084  1208 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNP 1280
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP 2960
 
Name Accession Description Interval E-value
Nucleic_acid_bd pfam13820
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ...
 48-189 1.08e-57

Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.


Pssm-ID: 463988  Cd Length: 143  Bit Score: 196.11  E-value: 1.08e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084     48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLWILAQSNNQQLRDLGILSV 127
Cdd:pfam13820    1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28380084    128 QIEGEGAINLALG---QNRSQDVRMnGPVASGNSVRMEAGFPMASGPGLIRMTSPAAVMTPQGGN 189
Cdd:pfam13820   79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLISDALPLHLRLAESGE 142
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 385-807 6.30e-11

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 67.73  E-value: 6.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    385 QQASQAHTNFPQMSNPGQFTAPQMKGLQGGPSRVPTPlqqPHLTNKSPASSPSSFQQGSPAssptVNQTQQQMGPRPPQN 464
Cdd:pfam09606   60 QQQPQGGQGNGGMGGGQQGMPDPINALQNLAGQGTRP---QMMGPMGPGPGGPMGQQMGGP----GTASNLLASLGRPQM 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    465 NPLSQGFQQPVSSPGRnpmVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPnfMQGQVPSTTAAt 544
Cdd:pfam09606  133 PMGGAGFPSQMSRVGR---MQPGGQAGGMMQPSSGQPGSGTPNQMGPNGGPGQGQAGGMNGGQQGP--MGGQMPPQMGV- 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    545 PGNSGALQLQaNQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN-----INNQQAGSSGVPQVTLGNMQGQPQQ 619
Cdd:pfam09606  207 PGMPGPADAG-AQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSqlgmgINQMQQMPQGVGGGAGQGGPGQPMG 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    620 GPPSQLMGMHQQIVPSQGQMAQQQGTLNPQNPMILSRAQLMPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQQGPQMMAPh 699
Cdd:pfam09606  286 PPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANP- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    700 nqmMGPQGQVLLQQNPMIEQIMTNQMQGNKAQFNSQNQSNVMP------GPAQIMRGPTPNmQGNMVQFTGQMSGQMLPQ 773
Cdd:pfam09606  365 ---MQRGQPGMMSSPSPVPGQQVRQVTPNQFMRQSPQPSVPSPqgpgsqPPQSHPGGMIPS-PALIPSPSPQMSQQPAQQ 440

                          410       420       430
                   ....*....|....*....|....*....|....
gi 28380084    774 QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHTD 807
Cdd:pfam09606  441 RTIGQDSPGGSLNTPGQSAVNSPLNPQEEQLYRE 474
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 623-774 1.74e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 49.81  E-value: 1.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    623 SQLMGMHQQIVPsqgqMAQQQGTLNPQNPMILSRAQLMPQGQMMVNAQNQNLGPSPQRMtPPKQMLPQQGPQMMAPhnqm 702
Cdd:TIGR01628  369 AHLQDQFMQLQP----RMRQLPMGSPMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMP-TPMGPGGPLRPNGLAP---- 439

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28380084    703 MGPQGQVLLQQNPMIEQimtNQMQGNKAQFNSQNQSNVMPGPAQimrGPTPNMQGNMvQFTGQMSGQMLPQQ 774
Cdd:TIGR01628  440 MNAVRAPSRNAQNAAQK---PPMQPVMYPPNYQSLPLSQDLPQP---QSTASQGGQN-KKLAQVLASATPQM 504
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1171-1808 2.46e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1171 PGPSPLSATQGATPQQP-PVNSLPSSHGH-HFPNvaAPTQTSRPKTP--------NRASPRPYYPQTPNNRPPSTEPSEI 1240
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPaPRPSEPAVTSRaRRPD--APPQSARPRAPvddrgdprGPAPPSPLPPDTHAPDPPPPSPSPA 2634

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1241 SLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPttlkaigQAPSNLTITNPPnfAAPQAhkldsvVVNSGKQS 1320
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAA-------QASSPPQRPRRR--AARPT------VGSLTSLA 2699

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1321 NPGTTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTSTTMLQnmelprnVLVGPTPLANPPLPGSFPNNTGl 1400
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA-------TPGGPARPARPPTTAGPPAPAP- 2771

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1401 nPQNPTVPVPAMGTVlednkesvnipqdsdcqnaqgrkeqvnteLKVVPTQEAKMAVPEDQSKKDGQPLDPNKLPSVEEN 1480
Cdd:PHA03247 2772 -PAAPAAGPPRRLTR-----------------------------PAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1481 KnlmSPAMREAPTSLSQlldnsGAPNVTIKPPGLTDLEVTPPVVSGEDLRKAsviptlqdPPSKEPSTSLSSPHSSePCS 1560
Cdd:PHA03247 2822 A---SPAGPLPPPTSAQ-----PTAPPPPPGPPPPSLPLGGSVAPGGDVRRR--------PPSRSPAAKPAAPARP-PVR 2884

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1561 TLARSELS-EVSSNAAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSSNTSAALPTHLQSALMSTVVTMPNVGN 1639
Cdd:PHA03247 2885 RLARPAVSrSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWL 2964

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1640 KVMVSeGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPS-TIPATPLTTNSGLMPPSVAVVGPLHIPQNIKFSSApvTP 1718
Cdd:PHA03247 2965 GALVP-GRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRvSSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDA--DS 3041

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1719 NVPSSSPAPNIQTGRPLvlssratpvqlpSPPCTSSPVVAPNPsvqqvkelNPDEASPQTNTSAdQSTLPPSQPTTVVSS 1798
Cdd:PHA03247 3042 LFDSDSERSDLEALDPL------------PPEPHDPFAHEPDP--------ATPEAGARESPSS-QFGPPPLSANAALSR 3100

                         650
                  ....*....|
gi 28380084  1799 LLTNSPGSSA 1808
Cdd:PHA03247 3101 RYVRSTGRSA 3110
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 1088-1324 2.96e-04

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 45.98  E-value: 2.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1088 PASVPPSPD-KQRMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPE-ASGSEV---PSVAGGPNNMPShLVVSQN 1162
Cdd:pfam08580  430 PGSSPPSSViMTPVNKGSKTPSSRRGSSFDFGSSSERVINSKLRRESKLPQiASTLKQtkrPSKIPRASPNHS-GFLSTP 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1163 QLMMTGPKPGPSplsATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRP---------YYPQTPNNRPP 1233
Cdd:pfam08580  509 SNTATSETPTPA---LRPPSRPQPPPPGNRPRWNASTNTNDLDVGHNFKPLTLTTPSPTPsrssrssstLPPVSPLSRDK 585

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1234 STEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNrgfdqqglNPTTLKAIGQAPSNLTITNPPNFAAPQAHKLDSVV 1313
Cdd:pfam08580  586 SRSPAPTCRSVSRASRRRASRKPTRIGSPNSRTSLLD--------EPPYPKLTLSKGLPRTPRNRQSYAGTSPSRSVSVS 657

                          250
                   ....*....|.
gi 28380084   1314 VNSGKQSNPGT 1324
Cdd:pfam08580  658 SGLGPQTRPGT 668
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1059-1280 1.62e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1059 PPRGPLNPDSQRMPVQQSgnVPVMVGLQGPASVPPSPDKQRMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPEA 1138
Cdd:PHA03247 2744 VPAGPATPGGPARPARPP--TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1139 ---SGSEVPSVAGGPNNMPSHLVVSQNQLMMTG--------PKPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1207
Cdd:PHA03247 2822 aspAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGsvapggdvRRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28380084  1208 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNP 1280
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP 2960
PHA03247 PHA03247
large tegument protein UL36; Provisional
 145-548 5.50e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 5.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   145 QDVRMNGPVASGNSVRMEAGfPMASGPGLIRMTSPAAVMTPQGGNMSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGL 224
Cdd:PHA03247 2594 QSARPRAPVDDRGDPRGPAP-PSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR 2672

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   225 HIQQQSHPSGSLPPAhhsmQPVPVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQTRPLQQHQqqpq 304
Cdd:PHA03247 2673 AAQASSPPQRPRRRA----ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV---- 2744

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   305 girPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGtmttnqgwkkaplPSPMQAQLQARPSLATVQTPSHPPPPYPFGS 384
Cdd:PHA03247 2745 ---PAGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------------GPPRRLTRPAVASLSESRESLPSPWDPADPP 2808

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   385 QQASQAHTNFPQMSNPGQFTAPQMKGLQGGPSRVPTPLQQPHLTNKSPA-------SSPSSFQQGSPASS--PTVNQTQQ 455
Cdd:PHA03247 2809 AAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVApggdvrrRPPSRSPAAKPAAParPPVRRLAR 2888

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   456 QMGPRPPQNNPLSQGFQQPVSSPG--RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFM 533
Cdd:PHA03247 2889 PAVSRSTESFALPPDQPERPPQPQapPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALV 2968

                         410
                  ....*....|....*
gi 28380084   534 QGQVPSTTAATPGNS 548
Cdd:PHA03247 2969 PGRVAVPRFRVPQPA 2983
 
Name Accession Description Interval E-value
Nucleic_acid_bd pfam13820
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ...
 48-189 1.08e-57

Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.


Pssm-ID: 463988  Cd Length: 143  Bit Score: 196.11  E-value: 1.08e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084     48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLWILAQSNNQQLRDLGILSV 127
Cdd:pfam13820    1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28380084    128 QIEGEGAINLALG---QNRSQDVRMnGPVASGNSVRMEAGFPMASGPGLIRMTSPAAVMTPQGGN 189
Cdd:pfam13820   79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLISDALPLHLRLAESGE 142
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 385-807 6.30e-11

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 67.73  E-value: 6.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    385 QQASQAHTNFPQMSNPGQFTAPQMKGLQGGPSRVPTPlqqPHLTNKSPASSPSSFQQGSPAssptVNQTQQQMGPRPPQN 464
Cdd:pfam09606   60 QQQPQGGQGNGGMGGGQQGMPDPINALQNLAGQGTRP---QMMGPMGPGPGGPMGQQMGGP----GTASNLLASLGRPQM 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    465 NPLSQGFQQPVSSPGRnpmVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPnfMQGQVPSTTAAt 544
Cdd:pfam09606  133 PMGGAGFPSQMSRVGR---MQPGGQAGGMMQPSSGQPGSGTPNQMGPNGGPGQGQAGGMNGGQQGP--MGGQMPPQMGV- 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    545 PGNSGALQLQaNQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN-----INNQQAGSSGVPQVTLGNMQGQPQQ 619
Cdd:pfam09606  207 PGMPGPADAG-AQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSqlgmgINQMQQMPQGVGGGAGQGGPGQPMG 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    620 GPPSQLMGMHQQIVPSQGQMAQQQGTLNPQNPMILSRAQLMPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQQGPQMMAPh 699
Cdd:pfam09606  286 PPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANP- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    700 nqmMGPQGQVLLQQNPMIEQIMTNQMQGNKAQFNSQNQSNVMP------GPAQIMRGPTPNmQGNMVQFTGQMSGQMLPQ 773
Cdd:pfam09606  365 ---MQRGQPGMMSSPSPVPGQQVRQVTPNQFMRQSPQPSVPSPqgpgsqPPQSHPGGMIPS-PALIPSPSPQMSQQPAQQ 440

                          410       420       430
                   ....*....|....*....|....*....|....
gi 28380084    774 QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHTD 807
Cdd:pfam09606  441 RTIGQDSPGGSLNTPGQSAVNSPLNPQEEQLYRE 474
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 287-752 1.65e-08

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 60.02  E-value: 1.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    287 QQQQLQTRPLQQHQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQ-GSLGTMTTNQGWKKAP--------LPSPM 357
Cdd:pfam09606   64 QGGQGNGGMGGGQQGMPDPINALQNLAGQGTRPQMMGPMGPGPGGPMGQQmGGPGTASNLLASLGRPqmpmggagFPSQM 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    358 QAQLQARPSLATvqtpsHPPPPYPFGSQQASQAHTNFPQMSnPGQFTAPQMKGLQGGPSRVPTPLQ------------QP 425
Cdd:pfam09606  144 SRVGRMQPGGQA-----GGMMQPSSGQPGSGTPNQMGPNGG-PGQGQAGGMNGGQQGPMGGQMPPQmgvpgmpgpadaGA 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    426 HLTNKSPASSPSSFQQGSPASSPTVNQTQQQMgpRPPQNNPLSQGFQQPVSSPGRNPMVQQGNVPPNFMvmqqqppnqgp 505
Cdd:pfam09606  218 QMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQ--QQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPM----------- 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    506 qslhPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTAATPGNSGALQLQANQNVQHAGGQGAGPPQNQMqvshGPPNMMQ 585
Cdd:pfam09606  285 ----GPPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVALGGLNHL----ETWNPGN 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    586 PSLMGIHGNINNQQAGSSGVPQVTLGNMQgqpQQGPPSQLMGMHQQIVPSQGQMAQQQGTLNPQNPMILSRAQLMPQGQM 665
Cdd:pfam09606  357 FGGLGANPMQRGQPGMMSSPSPVPGQQVR---QVTPNQFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSPALIPSPSPQM 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    666 MVNAQNQNLGPSPQRMTPPKQMLPQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKAQFNSQNQsnvMPGPA 745
Cdd:pfam09606  434 SQQPAQQRTIGQDSPGGSLNTPGQSAVNSPLNPQEEQLYREKYRQLTKYIEPLKRMIAKMENDPGDIDKMNK---MKRLL 510


                   ....*..
gi 28380084    746 QIMRGPT 752
Cdd:pfam09606  511 EILSNPS 517
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 438-717 3.58e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 55.43  E-value: 3.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    438 SFQQGSPASSPTVNQTQQQMGPRPPQNNPLSQGFQQPVSSpGRNPMVQQGNVPpnfmvmqqqppnqgpqSLHP--GLGGM 515
Cdd:pfam09770  103 NRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT-GYEKYKEPEPIP----------------DLQVdaSLWGV 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    516 PkrlPPGFSAGQANPnfmqgQVPSTTAATPGNS----------GALQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQ 585
Cdd:pfam09770  166 A---PKKAAAPAPAP-----QPAAQPASLPAPSrkmmsleeveAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFP 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    586 PSlmgihgninnqqagssgvpqvtlgNMQGQPQQGPPSQLMGMHQQIVPSQGQMAQQQGTLNPQNPMILSRAQLMPQGQM 665
Cdd:pfam09770  238 PQ------------------------IQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPP 293

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 28380084    666 MVNAQNQNLGPSPQRMTPPKQMLPQQGPQMMAP-HNQMMGPQGQVLLQQNPMI 717
Cdd:pfam09770  294 PVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPaPAHQAHRQQGSFGRQAPII 346
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 623-774 1.74e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 49.81  E-value: 1.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    623 SQLMGMHQQIVPsqgqMAQQQGTLNPQNPMILSRAQLMPQGQMMVNAQNQNLGPSPQRMtPPKQMLPQQGPQMMAPhnqm 702
Cdd:TIGR01628  369 AHLQDQFMQLQP----RMRQLPMGSPMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMP-TPMGPGGPLRPNGLAP---- 439

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28380084    703 MGPQGQVLLQQNPMIEQimtNQMQGNKAQFNSQNQSNVMPGPAQimrGPTPNMQGNMvQFTGQMSGQMLPQQ 774
Cdd:TIGR01628  440 MNAVRAPSRNAQNAAQK---PPMQPVMYPPNYQSLPLSQDLPQP---QSTASQGGQN-KKLAQVLASATPQM 504
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 616-759 2.15e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 49.42  E-value: 2.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    616 QPQQGPPSQ-LMGMHQQIVPSQGQMAQQQGTLNPQNPMilsraqLMPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQQGPQ 694
Cdd:TIGR01628  384 QLPMGSPMGgAMGQPPYYGQGPQQQFNGQPLGWPRMSM------MPTPMGPGGPLRPNGLAPMNAVRAPSRNAQNAAQKP 457

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28380084    695 MMAPHNQMMGPQGQVLLQQNPmieqimtnQMQGNKAQFNSqnqsnvMPGPAQIMRGPTPNMQGNM 759
Cdd:TIGR01628  458 PMQPVMYPPNYQSLPLSQDLP--------QPQSTASQGGQ------NKKLAQVLASATPQMQKQV 508
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 630-813 2.64e-05

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 49.26  E-value: 2.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    630 QQIVPSQGQMAQQQGTLNPQNPMILS--------RAQL-MPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQQGPQMMAPHN 700
Cdd:pfam09770  170 AAAPAPAPQPAAQPASLPAPSRKMMSleeveaamRAQAkKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQ 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    701 QMMGPQGQV------LLQQNPMIEQIMTNQMQGNKAQFNSQNQSNVMPGPAQIMrgPTPNMQGNMVQftgQMSGQMLPQQ 774
Cdd:pfam09770  250 PQQPQQHPGqghpvtILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQIL--QNPNRLSAARV---GYPQNPQPGV 324

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 28380084    775 GPVNNSPSQvmgiqgqvlRPPGPSPHMAQQHTDPVTTAN 813
Cdd:pfam09770  325 QPAPAHQAH---------RQQGSFGRQAPIITHPQQLAQ 354
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1171-1808 2.46e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1171 PGPSPLSATQGATPQQP-PVNSLPSSHGH-HFPNvaAPTQTSRPKTP--------NRASPRPYYPQTPNNRPPSTEPSEI 1240
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPaPRPSEPAVTSRaRRPD--APPQSARPRAPvddrgdprGPAPPSPLPPDTHAPDPPPPSPSPA 2634

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1241 SLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPttlkaigQAPSNLTITNPPnfAAPQAhkldsvVVNSGKQS 1320
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAA-------QASSPPQRPRRR--AARPT------VGSLTSLA 2699

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1321 NPGTTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTSTTMLQnmelprnVLVGPTPLANPPLPGSFPNNTGl 1400
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA-------TPGGPARPARPPTTAGPPAPAP- 2771

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1401 nPQNPTVPVPAMGTVlednkesvnipqdsdcqnaqgrkeqvnteLKVVPTQEAKMAVPEDQSKKDGQPLDPNKLPSVEEN 1480
Cdd:PHA03247 2772 -PAAPAAGPPRRLTR-----------------------------PAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1481 KnlmSPAMREAPTSLSQlldnsGAPNVTIKPPGLTDLEVTPPVVSGEDLRKAsviptlqdPPSKEPSTSLSSPHSSePCS 1560
Cdd:PHA03247 2822 A---SPAGPLPPPTSAQ-----PTAPPPPPGPPPPSLPLGGSVAPGGDVRRR--------PPSRSPAAKPAAPARP-PVR 2884

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1561 TLARSELS-EVSSNAAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSSNTSAALPTHLQSALMSTVVTMPNVGN 1639
Cdd:PHA03247 2885 RLARPAVSrSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWL 2964

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1640 KVMVSeGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPS-TIPATPLTTNSGLMPPSVAVVGPLHIPQNIKFSSApvTP 1718
Cdd:PHA03247 2965 GALVP-GRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRvSSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDA--DS 3041

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1719 NVPSSSPAPNIQTGRPLvlssratpvqlpSPPCTSSPVVAPNPsvqqvkelNPDEASPQTNTSAdQSTLPPSQPTTVVSS 1798
Cdd:PHA03247 3042 LFDSDSERSDLEALDPL------------PPEPHDPFAHEPDP--------ATPEAGARESPSS-QFGPPPLSANAALSR 3100

                         650
                  ....*....|
gi 28380084  1799 LLTNSPGSSA 1808
Cdd:PHA03247 3101 RYVRSTGRSA 3110
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 1088-1324 2.96e-04

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 45.98  E-value: 2.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1088 PASVPPSPD-KQRMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPE-ASGSEV---PSVAGGPNNMPShLVVSQN 1162
Cdd:pfam08580  430 PGSSPPSSViMTPVNKGSKTPSSRRGSSFDFGSSSERVINSKLRRESKLPQiASTLKQtkrPSKIPRASPNHS-GFLSTP 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1163 QLMMTGPKPGPSplsATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRP---------YYPQTPNNRPP 1233
Cdd:pfam08580  509 SNTATSETPTPA---LRPPSRPQPPPPGNRPRWNASTNTNDLDVGHNFKPLTLTTPSPTPsrssrssstLPPVSPLSRDK 585

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1234 STEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNrgfdqqglNPTTLKAIGQAPSNLTITNPPNFAAPQAHKLDSVV 1313
Cdd:pfam08580  586 SRSPAPTCRSVSRASRRRASRKPTRIGSPNSRTSLLD--------EPPYPKLTLSKGLPRTPRNRQSYAGTSPSRSVSVS 657

                          250
                   ....*....|.
gi 28380084   1314 VNSGKQSNPGT 1324
Cdd:pfam08580  658 SGLGPQTRPGT 668
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 459-660 6.59e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.03  E-value: 6.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    459 PRPPQNNPLSQGFQQPVSSPGRN---------PMVQQGNVPPNfmvmQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQAN 529
Cdd:pfam09770  170 AAAPAPAPQPAAQPASLPAPSRKmmsleeveaAMRAQAKKPAQ----QPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    530 PNFMQGQVPSTTAATPGNSgalQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPslMGIHGNINNQQAGSSGVPQVT 609
Cdd:pfam09770  246 PQQQPQQPQQHPGQGHPVT---ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQP--TQILQNPNRLSAARVGYPQNP 320

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 28380084    610 LGNMQGQPQQgppsqlmgmhqqivpsqgQMAQQQGTLNPQNPMILSRAQLM 660
Cdd:pfam09770  321 QPGVQPAPAH------------------QAHRQQGSFGRQAPIITHPQQLA 353
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1059-1280 1.62e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1059 PPRGPLNPDSQRMPVQQSgnVPVMVGLQGPASVPPSPDKQRMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPEA 1138
Cdd:PHA03247 2744 VPAGPATPGGPARPARPP--TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1139 ---SGSEVPSVAGGPNNMPSHLVVSQNQLMMTG--------PKPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1207
Cdd:PHA03247 2822 aspAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGsvapggdvRRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28380084  1208 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNP 1280
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP 2960
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1110-1413 2.19e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 43.37  E-value: 2.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1110 SNSRKMVYQENPQNSSSSP-LGEMSSLPEASGSEVPSVAGGPNNMPSHlvVSQNQLMMTGPKPGPSPLSATQGATPQQPP 1188
Cdd:pfam05109  414 TTTHKVIFSKAPESTTTSPtLNTTGFAAPNTTTGLPSSTHVPTNLTAP--ASTGPTVSTADVTSPTPAGTTSGASPVTPS 491

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1189 VNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPS---TEPSEISLSPE-RLNASIAGLFPPQINIPL 1263
Cdd:pfam05109  492 PSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTpTPNATSPTlgkTSPTSAVTTPTpNATSPTPAVTTPTPNATI 571

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1264 P-------------PRPNLNRGF--DQQGLNPTTLKAIGQAPSNLTITNPPNFAAPQAHKLDSVVVNSGKQS---NPGTT 1325
Cdd:pfam05109  572 PtlgktsptsavttPTPNATSPTvgETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSmslRPSSI 651

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   1326 KRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTSTTMLQNMELPR----NVLVGPTPLANPPLPGSFPNNTGLN 1401
Cdd:pfam05109  652 SETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRpgttSQASGPGNSSTSTKPGEVNVTKGTP 731

                          330
                   ....*....|..
gi 28380084   1402 PQNPTVPVPAMG 1413
Cdd:pfam05109  732 PKNATSPQAPSG 743
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1678-1820 2.63e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 2.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1678 PSTIPATPLTTNSGLMPPSVAVVGPlhiPQNIKFSSAPVTPNVPSSSPAPniQTGRPLVLSSRATPVQLPSPPCTSS-PV 1756
Cdd:PHA03247 2735 LPAAPAPPAVPAGPATPGGPARPAR---PPTTAGPPAPAPPAAPAAGPPR--RLTRPAVASLSESRESLPSPWDPADpPA 2809

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28380084  1757 VAPNPSVQQVKELNPDEASPQTNTSADQSTLPPSQPTTVVSSLLTN-SPGSSANRRSPVSSSKGK 1820
Cdd:PHA03247 2810 AVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSvAPGGDVRRRPPSRSPAAK 2874
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 679-845 2.85e-03

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 42.49  E-value: 2.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    679 QRMTPPKQMLPQQGPQMMAPH--NQMMGPQGQVLL-QQNPmieqimtnQMQGNKAQFNSQNQSNvMPGPAQIMRGPTPNM 755
Cdd:TIGR01628  366 QRRAHLQDQFMQLQPRMRQLPmgSPMGGAMGQPPYyGQGP--------QQQFNGQPLGWPRMSM-MPTPMGPGGPLRPNG 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    756 QGNMVQFTGQMSGQM-LPQQGPVNNSPSQVMGIQGQVLRP-PGPSPHMAQQHTDPVTTAnndvNLSQMMPDVSMQQ-ASM 832
Cdd:TIGR01628  437 LAPMNAVRAPSRNAQnAAQKPPMQPVMYPPNYQSLPLSQDlPQPQSTASQGGQNKKLAQ----VLASATPQMQKQVlGER 512

                          170
                   ....*....|...
gi 28380084    833 VPPHVQSMQGNSA 845
Cdd:TIGR01628  513 LFPLVEAIEPALA 525
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 551-706 2.92e-03

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 42.49  E-value: 2.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    551 LQLQANQNVQhaggQGAGPPQ-NQMQVSHGPPNMMQPslmgihgninNQQAGSSGVPQVTLGNMQGQPQQGPPSQLMGM- 628
Cdd:TIGR01628  371 LQDQFMQLQP----RMRQLPMgSPMGGAMGQPPYYGQ----------GPQQQFNGQPLGWPRMSMMPTPMGPGGPLRPNg 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    629 --HQQIVPSQGQMAQQQGTLNPQNPM-------ILSRAQLMPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQQGPQMMAPH 699
Cdd:TIGR01628  437 laPMNAVRAPSRNAQNAAQKPPMQPVmyppnyqSLPLSQDLPQPQSTASQGGQNKKLAQVLASATPQMQKQVLGERLFPL 516


                   ....*..
gi 28380084    700 NQMMGPQ 706
Cdd:TIGR01628  517 VEAIEPA 523
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 651-780 3.10e-03

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 42.49  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084    651 PMILSRAQLMPQGQMMVNAQNQNLGPSPQRMTPPKQMLPQQGPQMM---APHnQMMGPQGQVLLQQNPMIEQIMTnqMQG 727
Cdd:TIGR01628  355 PLYVALAQRKEQRRAHLQDQFMQLQPRMRQLPMGSPMGGAMGQPPYygqGPQ-QQFNGQPLGWPRMSMMPTPMGP--GGP 431

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 28380084    728 NKAQFNSQNQSNVMPGPAQIMRGPTPNMQGnmVQFTGQMSGQMLPQQGPVNNS 780
Cdd:TIGR01628  432 LRPNGLAPMNAVRAPSRNAQNAAQKPPMQP--VMYPPNYQSLPLSQDLPQPQS 482
PHA03247 PHA03247
large tegument protein UL36; Provisional
 145-548 5.50e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 5.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   145 QDVRMNGPVASGNSVRMEAGfPMASGPGLIRMTSPAAVMTPQGGNMSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGL 224
Cdd:PHA03247 2594 QSARPRAPVDDRGDPRGPAP-PSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR 2672

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   225 HIQQQSHPSGSLPPAhhsmQPVPVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQTRPLQQHQqqpq 304
Cdd:PHA03247 2673 AAQASSPPQRPRRRA----ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV---- 2744

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   305 girPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGtmttnqgwkkaplPSPMQAQLQARPSLATVQTPSHPPPPYPFGS 384
Cdd:PHA03247 2745 ---PAGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------------GPPRRLTRPAVASLSESRESLPSPWDPADPP 2808

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   385 QQASQAHTNFPQMSNPGQFTAPQMKGLQGGPSRVPTPLQQPHLTNKSPA-------SSPSSFQQGSPASS--PTVNQTQQ 455
Cdd:PHA03247 2809 AAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVApggdvrrRPPSRSPAAKPAAParPPVRRLAR 2888

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084   456 QMGPRPPQNNPLSQGFQQPVSSPG--RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFM 533
Cdd:PHA03247 2889 PAVSRSTESFALPPDQPERPPQPQapPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALV 2968

                         410
                  ....*....|....*
gi 28380084   534 QGQVPSTTAATPGNS 548
Cdd:PHA03247 2969 PGRVAVPRFRVPQPA 2983
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1168-1468 8.24e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 8.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1168 GPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPN--------------------VAAPTQTSRPKTPNRASPRPYYPQT 1227
Cdd:PHA03247 2606 GDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPhppptvppperprddpapgrVSRPRRARRLGRAAQASSPPQRPRR 2685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1228 PNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRgfdqQGLNPTTLKAIGQAPSNLTITnPPNFAAPQAH 1307
Cdd:PHA03247 2686 RAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAAR----QASPALPAAPAPPAVPAGPAT-PGGPARPARP 2760

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1308 KLDSVVVNSGKQSNPGTTKRASPSNSRRSSPGSSRKTTPSPgRQNSKAPKLTLASQTSTTMLQNMELPRNVLVGPTPLAN 1387
Cdd:PHA03247 2761 PTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP-WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP 2839

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380084  1388 PPLPGSFPNNTGLN-------------PQNPTVPVPAMGT----------VLEDNKESVNIPQDSDCQNAQGRKEQVNTE 1444
Cdd:PHA03247 2840 PPPPGPPPPSLPLGgsvapggdvrrrpPSRSPAAKPAAPArppvrrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQP 2919

                         330       340
                  ....*....|....*....|....
gi 28380084  1445 LKVVPTQEAKMAVPEDQSKKDGQP 1468
Cdd:PHA03247 2920 QPQPPPPPQPQPPPPPPPRPQPPL 2943
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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