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Conserved domains on  [gi|1775876184|gb|QGJ82975|]
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stiff stalk protein [Zea mays]

Protein Classification

F-box protein( domain architecture ID 10458603)

F-box protein may function as the substrate-recognition component of a SCF(Skp1-cullin-F-box) E3 ubiquitin ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins

Gene Ontology:  GO:0005515
PubMed:  31898225|11178263
SCOP:  4001927

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 31-72 9.59e-05

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


:

Pssm-ID: 425796  Cd Length: 43  Bit Score: 39.45  E-value: 9.59e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1775876184  31 WSRLPQPLVDRVLACLPTPSFLRLRAACRRFGNLIYSSPFLH 72
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVDSLKLWK 42
 
Name Accession Description Interval E-value
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 31-72 9.59e-05

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 39.45  E-value: 9.59e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1775876184  31 WSRLPQPLVDRVLACLPTPSFLRLRAACRRFGNLIYSSPFLH 72
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVDSLKLWK 42
FBOX smart00256
A Receptor for Ubiquitination Targets;
34-74 9.75e-04

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 36.65  E-value: 9.75e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1775876184   34 LPQPLVDRVLACLPTPSFLRLRAACRRFGNLIYSSPFLHSH 74
Cdd:smart00256   1 LPDEILEEILSKLDPKDLLRLRKVSRKWRSLIDSHDFWFKL 41
F-box_AtFBW1-like cd22157
F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) ...
 34-70 1.71e-03

F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) and similar proteins; AtFBW1, also called WD-40-associated F-box protein 1, is an F-box protein that contains four WD-40 repeats, which are separated from each other by a spacer region. Like other F-box proteins, AtFBW1 may be a component of SCF (Skp1 Cdc53 F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. This subfamily also contains many F-box only proteins that do not have any WD repeat. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438928  Cd Length: 39  Bit Score: 35.90  E-value: 1.71e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1775876184  34 LPQPLVDRVLACLPTPSFLRLRAACRRFGNLIYSSPF 70
Cdd:cd22157     3 LPDDLVEEILSRLPAKSLLRFRCVCKQWNSLISSPSF 39
 
Name Accession Description Interval E-value
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 31-72 9.59e-05

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 39.45  E-value: 9.59e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1775876184  31 WSRLPQPLVDRVLACLPTPSFLRLRAACRRFGNLIYSSPFLH 72
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVDSLKLWK 42
FBOX smart00256
A Receptor for Ubiquitination Targets;
34-74 9.75e-04

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 36.65  E-value: 9.75e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1775876184   34 LPQPLVDRVLACLPTPSFLRLRAACRRFGNLIYSSPFLHSH 74
Cdd:smart00256   1 LPDEILEEILSKLDPKDLLRLRKVSRKWRSLIDSHDFWFKL 41
F-box_AtFBW1-like cd22157
F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) ...
 34-70 1.71e-03

F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) and similar proteins; AtFBW1, also called WD-40-associated F-box protein 1, is an F-box protein that contains four WD-40 repeats, which are separated from each other by a spacer region. Like other F-box proteins, AtFBW1 may be a component of SCF (Skp1 Cdc53 F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. This subfamily also contains many F-box only proteins that do not have any WD repeat. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438928  Cd Length: 39  Bit Score: 35.90  E-value: 1.71e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1775876184  34 LPQPLVDRVLACLPTPSFLRLRAACRRFGNLIYSSPF 70
Cdd:cd22157     3 LPDDLVEEILSRLPAKSLLRFRCVCKQWNSLISSPSF 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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