NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1789852685|gb|QHB77830|]
View 

NADH dehydrogenase subunit 6 (mitochondrion) [Hylomyscus walterverheyeni]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
1-171 1.06e-73

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 218.90  E-value: 1.06e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFLAGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGSSWLIFGFLVIGILVELFFMWMVDYWNEIELV-NFDGLSDWMMYEVDDIGVMLEGGVGVAAMYSCVTWMMVVAGWSL 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVfNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161
                         170
                  ....*....|..
gi 1789852685 160 FTGIFIIIEITR 171
Cdd:MTH00109  162 FIGVFVIIEITR 173
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
1-171 1.06e-73

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 218.90  E-value: 1.06e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFLAGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGSSWLIFGFLVIGILVELFFMWMVDYWNEIELV-NFDGLSDWMMYEVDDIGVMLEGGVGVAAMYSCVTWMMVVAGWSL 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVfNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161
                         170
                  ....*....|..
gi 1789852685 160 FTGIFIIIEITR 171
Cdd:MTH00109  162 FIGVFVIIEITR 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-169 2.73e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 57.90  E-value: 2.73e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  17 IGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPETWGSSWLIFGFLVIGI 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1789852685  97 LVELFFMWMVDYWNEIELVNFDGLSdwmMYEVDDIGVmleggvgvaAMYSCVTWMMVVAGWSLFTGIFIIIEI 169
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPD---VGNIEAIGE---------LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
1-171 1.06e-73

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 218.90  E-value: 1.06e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFLAGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGSSWLIFGFLVIGILVELFFMWMVDYWNEIELV-NFDGLSDWMMYEVDDIGVMLEGGVGVAAMYSCVTWMMVVAGWSL 159
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVfNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161
                         170
                  ....*....|..
gi 1789852685 160 FTGIFIIIEITR 171
Cdd:MTH00109  162 FIGVFVIIEITR 173
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
1-171 1.08e-33

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 117.16  E-value: 1.08e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFLAGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGsSWLIFGFLVI-GILVELFFMWMVDYWNEIELVNFDGLSDWMMYEVDdigvmlegGVGVAAMYSCVTWMMVVAGWSL 159
Cdd:MTH00138   81 SWG-SWSVLGYVVGyLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGD--------VGGVALMYSSGGGMLVICAWVL 151
                         170
                  ....*....|..
gi 1789852685 160 FTGIFIIIEITR 171
Cdd:MTH00138  152 LLTLFVVLELTR 163
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
1-171 1.08e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 106.86  E-value: 1.08e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFLAGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGsSWLIFGFLVIGILVELFFMWMVDYWNEIELVNFDGLSDWMMYEVDdigvmlegGVGVAAMYSCVTWMMVVAGWSLF 160
Cdd:MTH00065   81 AWG-SWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYD--------WGGVGLMYSSGGWFLMISGWVLL 151
                         170
                  ....*....|.
gi 1789852685 161 TGIFIIIEITR 171
Cdd:MTH00065  152 LTLFVVLEVTR 162
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
1-171 5.68e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 94.82  E-value: 5.68e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFLAGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGSSWLIFGFLviGILVELFFMWMVDYWneieLVNFDGLSDWMMYEVDDIGVMLEGGvGVAAMYSCVTWMMVVAGWSLF 160
Cdd:MTH00115   81 AWGDWGVVGYVV--GFVLVVVVVGVVVGG----LWGMEGVGVVTVDSGGLFVVRLDFS-GVSLFYSSGGGGLLVCGWGLL 153
                         170
                  ....*....|.
gi 1789852685 161 TGIFIIIEITR 171
Cdd:MTH00115  154 LTLFVVLELVR 164
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
1-172 1.59e-14

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 67.32  E-value: 1.59e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFLAGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGSSWLIFGFLVIGILVELFFMWMVDYWNEIELVNFDGLSDwmmyevddigvmlEGGVGVAAMYSCVTWMMVVAGWSLF 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANN-------------LDLSGVSDLYSRGFFLLLLGGVVLF 147
                         170
                  ....*....|..
gi 1789852685 161 TGIFIIIEITRD 172
Cdd:MTH00214  148 LVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
1-171 2.91e-12

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 61.07  E-value: 2.91e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   1 MTYYIFSLSLLFlaGCIGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPE 80
Cdd:MTH00045    1 MVFYLFLILMLF--GSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  81 TWGSSWLIFGFLVIGILVELFFmwmvDYWNEIELVNFDGLSdwmmyevddigvmLEGGVGVAAMYSCVTWMMVVAGWSLF 160
Cdd:MTH00045   79 VSNLGEVLVLSLLLSLWVFISF----DNFLELSNNNWSLVS-------------LSDLVGSSELYNSGGLYLLLGGFILL 141
                         170
                  ....*....|.
gi 1789852685 161 TGIFIIIEITR 171
Cdd:MTH00045  142 VALVVALVISF 152
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-169 2.73e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 57.90  E-value: 2.73e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  17 IGLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPETWGSSWLIFGFLVIGI 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1789852685  97 LVELFFMWMVDYWNEIELVNFDGLSdwmMYEVDDIGVmleggvgvaAMYSCVTWMMVVAGWSLFTGIFIIIEI 169
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPD---VGNIEAIGE---------LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
24-126 3.35e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 39.10  E-value: 3.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685  24 SPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYPETWGSSWLIFGFLVIGILVELFFM 103
Cdd:MTH00152   22 QPLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGSNFKFVFFSLTLFGFLGLFFFFL 101
                          90       100
                  ....*....|....*....|...
gi 1789852685 104 WMVDYWNEIELVNFDGLSDWMMY 126
Cdd:MTH00152  102 YLYSSGGLSLSSLFDGSSGSLSF 124
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
8-106 2.07e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 36.91  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789852685   8 LSLLFLAGCIgLALKPSPIYGGLGLIISGFVGCLIILGFGGSFLGLLVFLIYLGGMMVVFGYTTAMATEEYpetWGSSWL 87
Cdd:MTH00212    7 LSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH---LFFKKY 82
                          90
                  ....*....|....*....
gi 1789852685  88 IFGFLVIGILVELFFMWMV 106
Cdd:MTH00212   83 FKGFGMILISLNLYLLLMT 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH