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Conserved domains on  [gi|1854744129|gb|QKR71659|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Timon tangitanus]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-217 5.17e-113

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00124:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 457  Bit Score: 330.62  E-value: 5.17e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00124  240 GYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00124  320 GLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTGLA 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLISG 217
Cdd:MTH00124  400 TLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISG 456
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-217 5.17e-113

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 330.62  E-value: 5.17e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00124  240 GYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00124  320 GLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTGLA 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLISG 217
Cdd:MTH00124  400 TLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISG 456
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-210 1.13e-38

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 139.06  E-value: 1.13e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFP-IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:COG1008   256 GYGLLRFALPLFPEASAYFAPlLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVS 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:COG1008   336 HGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAAL 415

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1854744129 160 GTLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTlmlhLMPMGLLIL 210
Cdd:COG1008   416 GLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAV----LAPLAALIL 462
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-161 1.90e-34

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 123.96  E-value: 1.90e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:pfam00361 129 GYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTH 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALA-NTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:pfam00361 209 GLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGV 288


                  ..
gi 1854744129 160 GT 161
Cdd:pfam00361 289 VG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-172 2.30e-33

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 124.67  E-value: 2.30e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFP-IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:TIGR01972 250 TYGFLRFNLPLFPDASLYFAPvLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQMIS 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:TIGR01972 330 HGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLAAL 409

                         170
                  ....*....|...
gi 1854744129 160 GTLITATYSLYMF 172
Cdd:TIGR01972 410 GIVLAAAYMLTLY 422
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-217 5.17e-113

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 330.62  E-value: 5.17e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00124  240 GYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00124  320 GLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTGLA 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLISG 217
Cdd:MTH00124  400 TLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISG 456
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-219 3.61e-106

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 313.39  E-value: 3.61e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00068  240 GYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALIQTPWSFSGAIILMISH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00068  320 GLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMVSLFNWSNWTILITGLG 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLISGLF 219
Cdd:MTH00068  400 TLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELISGMF 458
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-218 1.02e-93

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 281.40  E-value: 1.02e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00110  240 GYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMGATALMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00110  320 GLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIMSSFSWSNITIILMGLN 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLISGL 218
Cdd:MTH00110  400 MLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKIILGP 457
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-217 3.40e-83

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 254.50  E-value: 3.40e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00127  241 GYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMIAH 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00127  321 GLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTGLG 400

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLISG 217
Cdd:MTH00127  401 TLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWG 457
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-215 3.82e-80

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 246.39  E-value: 3.82e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00206  236 GYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKGALLLMIAH 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00206  316 GLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNFTLPLLGLG 395

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLI 215
Cdd:MTH00206  396 FLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-216 4.95e-69

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 217.92  E-value: 4.95e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVY-PHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:MTH00044  241 GYGLIRLINLFSlPSANNISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIFSGTNWGINGALILMIA 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:MTH00044  321 HGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLIISSIISWSILSFPIIGL 400

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1854744129 160 GTLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLIS 216
Cdd:MTH00044  401 ATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNIIL 457
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-215 4.89e-61

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 196.91  E-value: 4.89e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00163  228 GYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMGSLLMMIGH 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00163  308 GLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKLSMIFLMLL 387

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLI 215
Cdd:MTH00163  388 SFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLF 442
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-219 1.33e-57

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 187.35  E-value: 1.33e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00150  199 GYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSNTSWGWVGALIMMVSH 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00150  279 GFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIMIFPSLISYSPWFFVPLGLM 358

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLISGLF 219
Cdd:MTH00150  359 VFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLLFMWI 417
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-216 3.72e-55

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 181.86  E-value: 3.72e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00014  234 GYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSNTSWGWQGALAMMIAH 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00014  314 GLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLSTAILLAIT 393

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLIS 216
Cdd:MTH00014  394 SFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLIT 449
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-215 1.09e-54

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 180.56  E-value: 1.09e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:MTH00205  232 GYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNGAIIMMVAH 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG 160
Cdd:MTH00205  312 GLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKISGIPLSLI 391

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1854744129 161 TLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLI 215
Cdd:MTH00205  392 SFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKIF 446
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-210 1.13e-38

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 139.06  E-value: 1.13e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFP-IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:COG1008   256 GYGLLRFALPLFPEASAYFAPlLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVS 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:COG1008   336 HGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAAL 415

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1854744129 160 GTLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTlmlhLMPMGLLIL 210
Cdd:COG1008   416 GLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAV----LAPLAALIL 462
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-210 1.06e-34

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 128.40  E-value: 1.06e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPN-LIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:PRK05846  258 AYGLLRFSLPLFPDASHeFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIFAGNQLGIQGAIFQMIS 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:PRK05846  338 HGLSSAALFLLVGVLYDRLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLILLGSFQVNPVIAFIATT 417

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1854744129 160 GTLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTlmlhLMPMGLLIL 210
Cdd:PRK05846  418 GLILAAVYSLWLYQRVMFGPVKNEVAKLKDLNGRELLI----LLPLVALLL 464
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-161 1.90e-34

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 123.96  E-value: 1.90e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:pfam00361 129 GYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTH 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALA-NTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:pfam00361 209 GLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGV 288


                  ..
gi 1854744129 160 GT 161
Cdd:pfam00361 289 VG 290
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-215 3.24e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 127.10  E-value: 3.24e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFP-IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:MTH00204  256 GYGFLRFSWPLFPAASEYFAPlIVMLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLFTHTIEGLVAAVFLMLA 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:MTH00204  336 HGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSLLAAFEYSLGLGVLVTS 415

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1854744129 160 GTLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLI 215
Cdd:MTH00204  416 GMVWSAAYSLYLYNRISFGGGSNYLLFSRDLNRRELLAILPLIIAIFLLGIVPFII 471
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-215 8.59e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 125.93  E-value: 8.59e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFP-IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:MTH00217  253 GYGFIRFSWPLLPEASEYFSPlIQTLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIFSHTIQGLVAAIFLMLA 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:MTH00217  333 HGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSLLAAFEYSYIVGVLASL 412

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1854744129 160 GTLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLI 215
Cdd:MTH00217  413 GMVLSAGYSIYLYNRVCFGAPSKYLYFSRDLNRREFYVLLPLVFLIYLMGIFPFII 468
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-172 2.30e-33

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 124.67  E-value: 2.30e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFP-IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:TIGR01972 250 TYGFLRFNLPLFPDASLYFAPvLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQMIS 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:TIGR01972 330 HGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLAAL 409

                         170
                  ....*....|...
gi 1854744129 160 GTLITATYSLYMF 172
Cdd:TIGR01972 410 GIVLAAAYMLTLY 422
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-170 1.27e-28

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 111.94  E-value: 1.27e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYP-HPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:MTH00226  277 GYGLVRLSWPILPlGAQNLAPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGSIFIMLA 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:MTH00226  357 HGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSILSSFNWNPIIGVFVCS 436

                         170
                  ....*....|.
gi 1854744129 160 GTLITATYSLY 170
Cdd:MTH00226  437 GVILSAVYSFY 447
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-176 1.78e-21

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 91.36  E-value: 1.78e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPPNLIF--PIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:COG0651   253 YAILRVLTLLFGADPALFLgtLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLN 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGL 159
Cdd:COG0651   333 HALAKALLFLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLL 412

                         170
                  ....*....|....*...
gi 1854744129 160 -GTLITATYSLYMFLMTQ 176
Cdd:COG0651   413 lSSLLTLAYFVRIFGRAQ 430
ndhD CHL00011
NADH dehydrogenase subunit 4
 1-171 2.60e-21

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 91.16  E-value: 2.60e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFP-IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:CHL00011  258 AYGLIRINMELLPHAHSIFSPwLVIVGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAILQIIS 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELL----IITALFNWSSPTII 155
Cdd:CHL00011  338 HGFIGAALFFLAGTSYDRIRLVYLDEMGGIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIvffgIITSQKYLLMPKIL 417

                         170
                  ....*....|....*....
gi 1854744129 156 IT---GLGTLITATYSLYM 171
Cdd:CHL00011  418 ITfvmAIGMILTPIYLLSM 436
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-171 6.50e-19

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 84.31  E-value: 6.50e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPI-MILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:PRK12561  232 GYALIRFNVQMLPDAHVYFAPAlAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGIAAFTDLGISGAMLQMIS 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLI---ITALFNWSSP---- 152
Cdd:PRK12561  312 HGLIAAALFFLTGVTYERTHTLSIPNMGGLAKVMPKTFALFTASSMASLALPGMSGFVSELTVflgITSSDVYSSTfrti 391

                         170
                  ....*....|....*....
gi 1854744129 153 TIIITGLGTLITATYSLYM 171
Cdd:PRK12561  392 TILLAAVGLILTPIYLLSM 410
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-171 6.69e-16

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 75.51  E-value: 6.69e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   1 GYGLIRISSLVYPHPPNLIFPIMI-LALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIA 79
Cdd:PRK02546  260 GYALLRMNAGMLPDAHAQFAPLLIvLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGTSGAMLQMIS 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  80 HGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFN---WSSP-TII 155
Cdd:PRK02546  340 HGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAMWTACSLASLALPGMSGFVAELMVFVGFATsdaYTLPfRVV 419

                         170
                  ....*....|....*....
gi 1854744129 156 ITGL---GTLITATYSLYM 171
Cdd:PRK02546  420 VVFLaavGVILTPIYLLSM 438
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
2-196 7.64e-16

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 75.51  E-value: 7.64e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPPNLIFPIM-ILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:PRK06473  253 YGLLRFGVGLFPEAWVYLAPWLaTWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILAAVFQMISH 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFALANTNYERTHTRTLLLVRGL---QLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIIT 157
Cdd:PRK06473  333 GLISALLFLLVGVVYKKTGSRDVDVLRGLlnpERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGSFPIFPVQTLLC 412

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1854744129 158 GLGTLITATYSLYMFLMTQRGTLSTQFHLMPPSHTREHL 196
Cdd:PRK06473  413 MIGTGLTAVYFLLLVNRVFFGRLTAELSNLPRVLWSERL 451
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-167 1.58e-15

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 74.53  E-value: 1.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVY----PHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLM 77
Cdd:PRK08375  250 YALIRIYFTVFggdfRFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHL 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  78 IAHGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFN-WSSPTIII 156
Cdd:PRK08375  330 LHHALMKGALFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEaGQWLVLAV 409

                         170
                  ....*....|.
gi 1854744129 157 TGLGTLITATY 167
Cdd:PRK08375  410 LLASSLLALLY 420
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 23-170 1.83e-15

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 74.17  E-value: 1.83e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  23 MILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNYERTHTRT 102
Cdd:MTH00094  217 IIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGLMMMLAHGYTSTLMFYLIGEFYHISKSRL 296

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1854744129 103 LLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLGTLITATYSLY 170
Cdd:MTH00094  297 IYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSFFFIFFYFLVSFYYSLF 364
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 22-219 3.40e-12

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 64.79  E-value: 3.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  22 IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQttwSLTGAMVLMIAHGLSSSALFALANTNYERTHTR 101
Cdd:COG1009   278 VAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG---AYVAALFHLLTHAFFKALLFLGAGSVIHATGTR 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129 102 TLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLGTL---ITATYSLYMFLMTQRG 178
Cdd:COG1009   355 DIRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLLLAVALLgafLTAFYSFRLFFLVFFG 434

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1854744129 179 tlstQFHLMPPSHTREHLTLMlhLMPMGLLILkPSLISGLF 219
Cdd:COG1009   435 ----KPRPKTPKHPHESPWLM--TLPLVVLAV-LSLVLGLL 468
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-172 3.42e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 64.99  E-value: 3.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPPNLI-------FPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAM 74
Cdd:PRK12667  271 YAIIRFLYTIFGISPSLIdfraalsPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAAL 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  75 VLMIAHGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTI 154
Cdd:PRK12667  351 FHIINHAIAKSLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLP 430

                         170
                  ....*....|....*...
gi 1854744129 155 IITGLgtLITATYSLYMF 172
Cdd:PRK12667  431 ALVLL--IASAISLVGYF 446
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 13-219 8.41e-12

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 63.80  E-value: 8.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  13 PHPPNLIFpiMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALAN 92
Cdd:PRK06458  277 SDFPGRLL--LIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHSLTKSAIFFASG 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  93 TNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFN---WSSPTIIITGLGTLITAtysl 169
Cdd:PRK06458  355 NVLQKYGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLArgpLLIAILLLLLLTLAFAA---- 430

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1854744129 170 yMFLMTQRGTLSTqfhlmPPSHTREHLTLMLHLMPMGLLILKPsLISGLF 219
Cdd:PRK06458  431 -LVRRVAGMVFGE-----PPEAVNRGDLGWLTTSPMFVHLVLV-LVLGLY 473
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 38-162 1.61e-11

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 63.01  E-value: 1.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  38 LRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMS 117
Cdd:PRK12647  278 VRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFLVAHSLYKGALFMVAGIIDHETGTRDITKLGGLRRAMPITA 357

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1854744129 118 TWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLGTL 162
Cdd:PRK12647  358 AAALLAALSMAGLPPLFGFLAKELIYEALLEAPLWSLILTVAAVL 402
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
2-189 2.03e-11

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 62.42  E-value: 2.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPPNLIFPImiLALWG---ILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMI 78
Cdd:PRK07363  253 YGLLRFGLQLFPQTWSLVAPG--LAIIGtisVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLLGAVAQMI 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  79 AHGLSSSALFALANTNYERTHTRTLLLVRGLQ---LAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTII 155
Cdd:PRK07363  331 SHGLILALLFHLVGIVERKVGTRDLDVLNGLMnpiRGLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFSTFPIPTL 410

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1854744129 156 ITGLGTLITATYSLYMFLMTQRGTLSTQFHLMPP 189
Cdd:PRK07363  411 LCIVASGLTAVYFVILLNRTCFGRLDNKLAYYPK 444
PRK12650 PRK12650
DUF4040 family protein;
31-169 2.07e-11

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 62.75  E-value: 2.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  31 LMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNYERTHTRTLLLVRGLQ 110
Cdd:PRK12650  284 LMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRDIRRLGSLW 363

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1854744129 111 LAFPLmSTWWLLINLTNMA-MPPSINLVGELLIITALF-----NWSSPTIIIT-GLGTLITATYSL 169
Cdd:PRK12650  364 RRMPF-TFVSVTIAALSMAaVPPLFGFVSKEGMLTAFLeapggNAGVVLLLVGaALGAVFTFAYSA 428
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 22-145 1.11e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 51.27  E-value: 1.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  22 IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANT---NYERT 98
Cdd:PRK12662  282 FMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSisyHFGTT 361

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1854744129  99 HTRTLLlvrGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITA 145
Cdd:PRK12662  362 KLEDCL---NLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDA 405
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 2-147 2.03e-07

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 50.88  E-value: 2.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPhpPNLIFPIMILALWGI--LMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQT-----------TW 68
Cdd:PRK08667  253 YGLVRFLMDVLS--PELWWGVLILLAGSIsaLLGVIYALKEHDLKGLLAYSSIENIGIILMGIGLYVifgvygldtlaLL 330

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1854744129  69 SLTGAMVLMIAHGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALF 147
Cdd:PRK08667  331 ALGGALFHSLNHALFKSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFASELLLYESFF 409
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-164 4.15e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 49.57  E-value: 4.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVyphpPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAiilqttwSLTGAmVLMIAHG 81
Cdd:PRK07234  232 FPLVRCALDV----PGLDLIVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQLGFILAA-------PLVGG-LYALAHG 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  82 LSSSALFALANTNYERTHTRTLLLVRGLQLAFPLmstwwLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLGT 161
Cdd:PRK07234  300 LVKSTLFLCAGALPSRNFTELISQMLGIGKWIPL-----TMASFSIAGFPLLAGFVSKVLTLKNLLPWQAIALNLAAVGT 374


                  ...
gi 1854744129 162 LIT 164
Cdd:PRK07234  375 AAS 377
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 26-174 1.05e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 48.66  E-value: 1.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  26 ALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNYERTHTRTLLL 105
Cdd:PRK06589  287 PIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQVDK 366

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1854744129 106 VRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPT--IIITGLGTLITATYSLYMFLM 174
Cdd:PRK06589  367 LHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWlsIIVMLVVIASSILSALYLLKI 437
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
22-90 1.11e-06

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 48.28  E-value: 1.11e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1854744129  22 IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFAL 90
Cdd:PRK05777  273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMTLGAFGV 341
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 22-167 6.96e-06

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 45.91  E-value: 6.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  22 IMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNYERTHTR 101
Cdd:PRK08377  276 VIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVDAGVFHMINHAIVKALLFLAVGYVGITLGGT 355

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1854744129 102 TLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLG-TLITATY 167
Cdd:PRK08377  356 EIEKFEGLGKRMPLTALALTIGALSTVGIPLFNVFWSKFRIILAGLSAGYTWPVALVLGaSVVEAVY 422
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 38-89 9.44e-06

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 45.49  E-value: 9.44e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1854744129  38 LRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFA 89
Cdd:COG1007   288 LAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFA 339
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
13-171 1.01e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 45.41  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  13 PHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALAN 92
Cdd:PRK06277  260 SYFPSAQGVLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAG 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  93 TNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTI----IITGLGTLIT---A 165
Cdd:PRK06277  340 IVSYRTKTSNLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELaiimIIVSIGTFVSmmkA 419


                  ....*.
gi 1854744129 166 TYSLYM 171
Cdd:PRK06277  420 FYLIYL 425
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 23-170 1.54e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 45.30  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  23 MILALWgilmtssICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNYERTHTRT 102
Cdd:PRK12644  278 MLLGGW-------RALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLAMLLAHALFKAALFLVVGIIDHSTGTRD 350

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1854744129 103 LLLVRGLQLAFPLMsTWWLLINLTNMA-MPPSINLVGELLIITALFNWSSP----TIIITG--LGTLITATYSLY 170
Cdd:PRK12644  351 IRKLSGLGRRQPVL-AVVAALAAASMAgLPPLLGFVAKEAALEAVLHDGALgpagPVVLAGivLGSILTVAYSLR 424
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-170 2.79e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 44.19  E-value: 2.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPpNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHG 81
Cdd:PRK12665  257 YAIIRTHTLLFPGG-GLDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGLSGAIYYVAHHI 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  82 LSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITGLGT 161
Cdd:PRK12665  336 TVQTTLFLVVGLIERQAGSSSLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGTWLAWALVAGG 415


                  ....*....
gi 1854744129 162 LITATYSLY 170
Cdd:PRK12665  416 VVTSLLTLY 424
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 2-88 3.16e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 43.98  E-value: 3.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPPNLIFPIMILALwGILMTSSIC---LRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMI 78
Cdd:PRK08676  254 YGILRLSALLRQSGAAEQFSNVLIGL-GIFSIAVAAfsmLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332

                          90
                  ....*....|
gi 1854744129  79 AHGLSSSALF 88
Cdd:PRK08676  333 AHSLVKSGLF 342
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 2-162 5.90e-05

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 43.42  E-value: 5.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAI---ILQTTWSLTGAMVLMI 78
Cdd:PRK06525  255 YIFARAIQSMGPIPHVIGYVGAVMAIVTLLYGFLMYLPQQDMKRLLAYSTITQLGYMFFGLslaILGSRLALEGSIAYIF 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  79 AHGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITG 158
Cdd:PRK06525  335 NHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLVGVGFCVAALAITGVPPFNGFFSKFPIFAAGFELSVEYWILLP 414


                  ....
gi 1854744129 159 LGTL 162
Cdd:PRK06525  415 AMVL 418
PRK12646 PRK12646
DUF4040 family protein;
19-183 1.88e-04

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 42.05  E-value: 1.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  19 IFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQT--------------TWSLTGAMVLMIAHGLSS 84
Cdd:PRK12646  274 IYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGgyaqhqqdaiasiyVFVLFAALFHLMNHAIFK 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  85 SALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWS-------SPTIIIT 157
Cdd:PRK12646  354 CALFMGVGIIDHEAGTRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGqlsqfslISMIIIV 433

                         170       180
                  ....*....|....*....|....*....
gi 1854744129 158 GLG---TLITATYSLYMFLMTQRGTLSTQ 183
Cdd:PRK12646  434 FIGviaSIFTFTYALYMVKEVFWGKYDSK 462
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 2-215 2.71e-04

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 41.09  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRIS-SLVYPHPPNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAH 80
Cdd:TIGR01770 251 AVFLRLFlYILFGFSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIY 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  81 GLSSSALFA--LANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLIITALFNWSSPTIIITG 158
Cdd:TIGR01770 331 ALMSLGAFGvlSLLRSYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIA 410

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1854744129 159 -LGTLITATYSL----YMFLMTQRgtlstQFHLMPPSHTREHLTLMLHLMPMGLLILKPSLI 215
Cdd:TIGR01770 411 vLTSVIGAFYYLrvvkVMYFDKPE-----RRIPSNPQSKAQSLLLSISALFILFLGLFPSLI 467
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 16-100 1.13e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 39.59  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  16 PNLIFPIMILALWGILMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNY 95
Cdd:PRK08668  269 PLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVI 348


                  ....*
gi 1854744129  96 ERTHT 100
Cdd:PRK08668  349 YRTGT 353
PRK12648 PRK12648
putative monovalent cation/H+ antiporter subunit A; Reviewed
 31-118 1.29e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237157 [Multi-domain]  Cd Length: 948  Bit Score: 39.40  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  31 LMTSSICLRQTDLKALIAYSSVSHMGLVTTAIILQTTWSLTGAMVLMIAHGLSSSALFALANTNYERTHTRTLLLVRGLQ 110
Cdd:PRK12648  283 LLGAYFALFQHDLKGLLAYSTISHLGLITLLLGLGSPLAAVAAIFHIINHATFKASLFMAAGIIDHETGTRDMRRLSGLR 362


                  ....*...
gi 1854744129 111 LAFPLMST 118
Cdd:PRK12648  363 RLMPITAT 370
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-148 8.76e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 36.61  E-value: 8.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129   2 YGLIRISSLVYPHPPNLIFP---IMILALWGILMTSSICLRQTDLKALIAYSSVSHMG---------LVTTAIILQTTW- 68
Cdd:PRK08376  267 YALARVLFSIYGPAINLATVgwvIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGymllglgvgLAALGDPAMASYg 346

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1854744129  69 --SLTGAMVLMIAHGLSSSALFALANTNYERTHTRTLLLVRGLQLAFPLMSTWWLLINLTNMAMPPSINLVGELLII--T 144
Cdd:PRK08376  347 eiALAGGIYHIVNHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYesS 426


                  ....
gi 1854744129 145 ALFN 148
Cdd:PRK08376  427 ALFN 430
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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