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Conserved domains on  [gi|1869261161|gb|QLH12247|]
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monomeric alpha-amylase inhibitor [Triticum aestivum]

Protein Classification

alpha-amylase inhibitor/seed storage family protein( domain architecture ID 10083580)

alpha-amylase inhibitors (AAIs) and seed storage (SS) proteins play an important role in the natural defenses of plants against insects and pathogens such as fungi, bacteria and viruses; AAIs impede the digestion of plant starch and proteins by inhibiting digestive alpha-amylases and proteinases.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AAI_SS cd00261
AAI_SS: Alpha-Amylase Inhibitors (AAIs) and Seed Storage (SS) Protein subfamily; composed of ...
 36-133 2.10e-14

AAI_SS: Alpha-Amylase Inhibitors (AAIs) and Seed Storage (SS) Protein subfamily; composed of cereal-type AAIs and SS proteins. They are mainly present in the seeds of a variety of plants. AAIs play an important role in the natural defenses of plants against insects and pathogens such as fungi, bacteria and viruses. AAIs impede the digestion of plant starch and proteins by inhibiting digestive alpha-amylases and proteinases. Also included in this subfamily are SS proteins such as 2S albumin, gamma-gliadin, napin, and prolamin. These AAIs and SS proteins are also known allergens in humans.


:

Pssm-ID: 238163  Cd Length: 110  Bit Score: 65.12  E-value: 2.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869261161  36 WCDPATGYKVSALTGCRAMVKLQCVG--------SQVPEAVLRDCCQQLADInNEWCRCGDLSSTLRSVYQELGVRegKE 107
Cdd:cd00261     3 QCQPGQQQPQQPLNSCREYLRQQCSGvggppvwpQQSCEVLRQQCCQQLAQI-PEQCRCEALRQMVQGVIQQQQQQ--QE 79

                          90       100
                  ....*....|....*....|....*.
gi 1869261161 108 VLPGCRKEVMKLTAASVPEVCKVPIP 133
Cdd:cd00261    80 QQQGQEVERMRQAAQNLPSMCNLYPP 105
 
Name Accession Description Interval E-value
AAI_SS cd00261
AAI_SS: Alpha-Amylase Inhibitors (AAIs) and Seed Storage (SS) Protein subfamily; composed of ...
 36-133 2.10e-14

AAI_SS: Alpha-Amylase Inhibitors (AAIs) and Seed Storage (SS) Protein subfamily; composed of cereal-type AAIs and SS proteins. They are mainly present in the seeds of a variety of plants. AAIs play an important role in the natural defenses of plants against insects and pathogens such as fungi, bacteria and viruses. AAIs impede the digestion of plant starch and proteins by inhibiting digestive alpha-amylases and proteinases. Also included in this subfamily are SS proteins such as 2S albumin, gamma-gliadin, napin, and prolamin. These AAIs and SS proteins are also known allergens in humans.


Pssm-ID: 238163  Cd Length: 110  Bit Score: 65.12  E-value: 2.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869261161  36 WCDPATGYKVSALTGCRAMVKLQCVG--------SQVPEAVLRDCCQQLADInNEWCRCGDLSSTLRSVYQELGVRegKE 107
Cdd:cd00261     3 QCQPGQQQPQQPLNSCREYLRQQCSGvggppvwpQQSCEVLRQQCCQQLAQI-PEQCRCEALRQMVQGVIQQQQQQ--QE 79

                          90       100
                  ....*....|....*....|....*.
gi 1869261161 108 VLPGCRKEVMKLTAASVPEVCKVPIP 133
Cdd:cd00261    80 QQQGQEVERMRQAAQNLPSMCNLYPP 105
AAI smart00499
Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain ...
 45-135 9.32e-08

Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family;


Pssm-ID: 214698  Cd Length: 79  Bit Score: 46.99  E-value: 9.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869261161   45 VSALTGCRAMVKLQCVGsqvpEAVLRDCCQQLADINNEWCRCGDLSSTLRSVYQELgvregkevlpgcrkEVMKLTAASV 124
Cdd:smart00499   5 LLQLAPCLSYLVGGSRG----APPSQQCCSQLRGLNSAQCRCLALRAAVLGILEIP--------------GLNAQNAASL 66

                           90
                   ....*....|.
gi 1869261161  125 PEVCKVPIPNP 135
Cdd:smart00499  67 PSACGVPPPYT 77
Tryp_alpha_amyl pfam00234
Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase ...
 67-135 2.73e-04

Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase inhibitors, seed storage proteins and lipid transfer proteins from plants.


Pssm-ID: 425543  Cd Length: 74  Bit Score: 37.55  E-value: 2.73e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869261161  67 AVLRDCCQQLADINnEWCRCGDLSSTLRSVyqelgvregkevlpgcrKEVMKLTAASVPEVCKVPIPNP 135
Cdd:pfam00234  21 VPSQQCCSQLRQLQ-AQCRCTAIRAIVLGI-----------------EGINPQAAASLPSMCGVNVPYG 71
 
Name Accession Description Interval E-value
AAI_SS cd00261
AAI_SS: Alpha-Amylase Inhibitors (AAIs) and Seed Storage (SS) Protein subfamily; composed of ...
 36-133 2.10e-14

AAI_SS: Alpha-Amylase Inhibitors (AAIs) and Seed Storage (SS) Protein subfamily; composed of cereal-type AAIs and SS proteins. They are mainly present in the seeds of a variety of plants. AAIs play an important role in the natural defenses of plants against insects and pathogens such as fungi, bacteria and viruses. AAIs impede the digestion of plant starch and proteins by inhibiting digestive alpha-amylases and proteinases. Also included in this subfamily are SS proteins such as 2S albumin, gamma-gliadin, napin, and prolamin. These AAIs and SS proteins are also known allergens in humans.


Pssm-ID: 238163  Cd Length: 110  Bit Score: 65.12  E-value: 2.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869261161  36 WCDPATGYKVSALTGCRAMVKLQCVG--------SQVPEAVLRDCCQQLADInNEWCRCGDLSSTLRSVYQELGVRegKE 107
Cdd:cd00261     3 QCQPGQQQPQQPLNSCREYLRQQCSGvggppvwpQQSCEVLRQQCCQQLAQI-PEQCRCEALRQMVQGVIQQQQQQ--QE 79

                          90       100
                  ....*....|....*....|....*.
gi 1869261161 108 VLPGCRKEVMKLTAASVPEVCKVPIP 133
Cdd:cd00261    80 QQQGQEVERMRQAAQNLPSMCNLYPP 105
AAI smart00499
Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain ...
 45-135 9.32e-08

Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family;


Pssm-ID: 214698  Cd Length: 79  Bit Score: 46.99  E-value: 9.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869261161   45 VSALTGCRAMVKLQCVGsqvpEAVLRDCCQQLADINNEWCRCGDLSSTLRSVYQELgvregkevlpgcrkEVMKLTAASV 124
Cdd:smart00499   5 LLQLAPCLSYLVGGSRG----APPSQQCCSQLRGLNSAQCRCLALRAAVLGILEIP--------------GLNAQNAASL 66

                           90
                   ....*....|.
gi 1869261161  125 PEVCKVPIPNP 135
Cdd:smart00499  67 PSACGVPPPYT 77
Tryp_alpha_amyl pfam00234
Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase ...
 67-135 2.73e-04

Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase inhibitors, seed storage proteins and lipid transfer proteins from plants.


Pssm-ID: 425543  Cd Length: 74  Bit Score: 37.55  E-value: 2.73e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869261161  67 AVLRDCCQQLADINnEWCRCGDLSSTLRSVyqelgvregkevlpgcrKEVMKLTAASVPEVCKVPIPNP 135
Cdd:pfam00234  21 VPSQQCCSQLRQLQ-AQCRCTAIRAIVLGI-----------------EGINPQAAASLPSMCGVNVPYG 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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