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Conserved domains on  [gi|1896828160|gb|QNJ59970|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Gymnoscirtetes pusillus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 9.27e-89

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 269.39  E-value: 9.27e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   1 MTNNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  81 KYPMSWEmelIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQMStFMFTIIILSIII 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 241 FLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSYSENSWSMTNKLNKSKFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1896828160 321 MTVMISTLGLMSTSMMISL 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 9.27e-89

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 269.39  E-value: 9.27e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   1 MTNNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  81 KYPMSWEmelIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQMStFMFTIIILSIII 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 241 FLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSYSENSWSMTNKLNKSKFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1896828160 321 MTVMISTLGLMSTSMMISL 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-270 1.30e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 81.59  E-value: 1.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  24 SNSWFGVWMGLEINLLSFIPMLA-NNKNTMMNESSIKYFIVQAMASTMLLFSILLI--------------QMKYPMSWEM 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  89 ELIPSMMVSSSLLLKIGAAPFHFWFPEV-MGTSTWINCLTLMTWQKIAPMMTL-------SYCIQMSTFMFTIIILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAyEGAPTPVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMV----SENVWELYFIIYSLLSLIMVILF-----KQMNLFFLNQIYSSTN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1896828160 232 MKTEIKFMMFLSLLSLGGLPPFLGFLPKWIVMQYLVENN 270
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAAS 279
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-330 4.54e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 66.51  E-value: 4.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   8 LLFLSTLmmGTILSISSNSWFGVWMGLEI-NLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLI-------- 78
Cdd:TIGR01770 107 LLLFALL--GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgsln 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  79 --QMKYPMSWEMELIPSM-----MVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIA---PMMTLSYCIQ--- 145
Cdd:TIGR01770 185 feDLLLFLSNGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 146 ---MSTFMFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMISSLMVS-----ENVWeLYFIIYSLLSLIMVILFKQ 217
Cdd:TIGR01770 265 seaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGtlegiKAVL-FYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 218 MNLFFLNQIYSSTNMKTEIK------FMMFLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMR 291
Cdd:TIGR01770 344 LRSYKDEWIEYISDFAGLFKtnpilaILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1896828160 292 IsfSALILSYSENSWSMTNKLNKSKfilPMTVMISTLGL 330
Cdd:TIGR01770 424 V--VKVMYFDKPERRIPSNPQSKAQ---SLLLSISALFI 457
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-209 6.07e-10

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 60.13  E-value: 6.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   8 LLFLSTLmmGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMM-NESSIKYFIVQAMASTMLLFSILLI-------- 78
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAFRRDDRRsSEAALKYFLLGALSSGFLLYGISLLygatgsln 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  79 ------QMKYPMSWEMELIPSM-MVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTL---------SY 142
Cdd:COG1007   185 lagiaaALAAGGANSPLLLLGLvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1896828160 143 CIQMSTFMFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMISSLMV-SENVWE---LYFIIYSLLSL 209
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLFMNL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 9.27e-89

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 269.39  E-value: 9.27e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   1 MTNNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  81 KYPMSWEmelIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQMStFMFTIIILSIII 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 241 FLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSYSENSWSMTNKLNKSKFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1896828160 321 MTVMISTLGLMSTSMMISL 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 3-339 4.01e-50

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 170.50  E-value: 4.01e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   3 NNSTKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILlIQMKY 82
Cdd:MTH00041    2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGAL-IQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  83 PMSW----EMELIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQM--STFMFTIIIL 156
Cdd:MTH00041   81 SGSWsingPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLlnSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 157 SIIIGAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEI 236
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 237 KFMMFLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSYSENSWSMTNKLNKSK 316
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                         330       340
                  ....*....|....*....|....*...
gi 1896828160 317 F-----ILPMTVMISTLGLMSTSMMISL 339
Cdd:MTH00041  321 ItvygvILSILSSISILGLLLIPLFLSF 348
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-339 3.35e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 168.10  E-value: 3.35e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   8 LLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSIlLIQMKYPMSWE 87
Cdd:MTH00105    7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAI-IINLMYSGQWT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  88 MELIP----SMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTL---SYCIQMsTFMFTIIILSIII 160
Cdd:MTH00105   86 ITKLTnptaSTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILyqiSPSINP-NLLLTLAILSILI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMM 240
Cdd:MTH00105  165 GGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLI 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 241 FLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFS-ALILSYSENSWSMTNKLNKSK--F 317
Cdd:MTH00105  245 LLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYStSLTMFPSTNNMKMKWQFENTKpmT 324

                         330       340
                  ....*....|....*....|..
gi 1896828160 318 ILPMTVMISTLGLMSTSMMISL 339
Cdd:MTH00105  325 LLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 6-339 4.65e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 165.00  E-value: 4.65e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   6 TKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSIlLIQMKYPMS 85
Cdd:MTH00112    5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSS-TTNAWNTGQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  86 WEMEL----IPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQM--STFMFTIIILSII 159
Cdd:MTH00112   84 WDITQltnpTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlnPTLLLTLAILSTL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 160 IGAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFM 239
Cdd:MTH00112  164 IGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTT 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 240 MFLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSySENSWSMTNK---LNKSK 316
Cdd:MTH00112  244 LMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITL-PPNTTNMMMKwrtKPKKN 322

                         330       340
                  ....*....|....*....|...
gi 1896828160 317 FILPMTVMISTLGLMSTSMMISL 339
Cdd:MTH00112  323 TLTATLTTLSTLLLPLSPMILTI 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-339 7.26e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 162.01  E-value: 7.26e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  10 FLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILlIQMKYPMSWEM- 88
Cdd:MTH00070    9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSST-INAWFTGEWTIm 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  89 ---ELIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLsycIQMS-----TFMFTIIILSIII 160
Cdd:MTH00070   88 nmqTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALL---IQIShllnsNLLIIMGLLSTLI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMM 240
Cdd:MTH00070  165 GGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMM 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 241 FLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFsALILSYS---ENSWSMTNKLNKSKF 317
Cdd:MTH00070  245 MLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSY-AMSLTTSpntSNSKLYWRFKNKTNN 323

                         330       340
                  ....*....|....*....|..
gi 1896828160 318 ILPMTVMISTLGLMSTSMMISL 339
Cdd:MTH00070  324 LLSLTIILSLMLLPITPTILNL 345
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-339 5.59e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 159.36  E-value: 5.59e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   6 TKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLIQM---KY 82
Cdd:MTH00200    5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWtsgQW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  83 PMSWEMELIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLS--YCIQMSTFMFTIIILSIII 160
Cdd:MTH00200   85 GISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMM 240
Cdd:MTH00200  165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 241 FLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSYSENSWSMTNKLNKSKFILP 320
Cdd:MTH00200  245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSNSNLL 324

                         330       340
                  ....*....|....*....|.
gi 1896828160 321 MT--VMISTLGLMSTSMMISL 339
Cdd:MTH00200  325 VGllLLLSILGLPLTPQLLFL 345
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-328 2.35e-45

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 157.14  E-value: 2.35e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   9 LFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLIQMKYPMSwem 88
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLS--- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  89 eLIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQMSTFMFTIIILSIIIGAMGGLNQ 168
Cdd:MTH00197   79 -LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 169 TSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMMFLSLLSLG 248
Cdd:MTH00197  158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 249 GLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSYSENSWSMTNKLNKSKFILPMTVMISTL 328
Cdd:MTH00197  238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLMMMLPLL 317
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 7-337 1.54e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 152.73  E-value: 1.54e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   7 KLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSIlLIQMKYPMSW 86
Cdd:MTH00144    6 NLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGS-LIMYNLSFSW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  87 EMelipSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCI---QMSTFMFTIIILSIIIGAM 163
Cdd:MTH00144   85 FS----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLdlyWLAYLLCVISVLSALVGSI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 164 GGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMMFlS 243
Cdd:MTH00144  161 GGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIIS-L 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 244 LLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALIlsysenSWSMTNKLNKSKFILPMTV 323
Cdd:MTH00144  240 LLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL------SSSKSKKSNSSKVLNSSII 313

                         330
                  ....*....|....
gi 1896828160 324 MISTLGLMSTSMMI 337
Cdd:MTH00144  314 SLNLLGGLLFLLLY 327
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-321 2.17e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 147.23  E-value: 2.17e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   6 TKLLFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSIlliQMKYPMS 85
Cdd:MTH00011    7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM---TMMWSFP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  86 WEMELIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYC--IQMSTFMFTIIILSIIIGAM 163
Cdd:MTH00011   84 SLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSALAGGL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 164 GGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTNMKTEIKFMMFLS 243
Cdd:MTH00011  164 GGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIM 243

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1896828160 244 LLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFSALILSYSENSWSMTNKLNKSKFILPM 321
Cdd:MTH00011  244 LLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPTFSSLKSAPYEPKTKILISM 321
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-330 7.43e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 140.71  E-value: 7.43e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   9 LFLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSIL----------LI 78
Cdd:MTH00135    8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  79 QMKYPmswemelIPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMmTLSYCIQ--MSTFMFTIIIL 156
Cdd:MTH00135   88 QMSHP-------LPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAptNPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 157 SIIIGAMGGLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVILFKQMNLFFLNQIYSSTnMKTEI 236
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSW-TKAPA 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 237 KFMMFLSLLSLGGLPPFL-GFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRISFS-ALILSYSENSWSMTNKLNK 314
Cdd:MTH00135  239 LTALTPLILLSLGGLPPLtGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAmTLTISPNTLNGTTPWRLPS 318

                         330
                  ....*....|....*..
gi 1896828160 315 SKFILPM-TVMISTLGL 330
Cdd:MTH00135  319 TQLTLPLaISTTATLML 335
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-319 5.15e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 83.93  E-value: 5.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  16 MGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMN-ESSIKYFIVQAMASTMLLFSI----------------LLI 78
Cdd:MTH00196    4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFGCallcgttgglhlsyinLVL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  79 QMKYPMSWEMELIPSMMVSSSLLLKIGAAPFHFWFPEVM-GTSTWINCLtLMTWQKIAPMMTLSYCIQMSTFMFTIIILS 157
Cdd:MTH00196   84 NSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYeGAPTKTTAL-LAIVPKLGIFSILVSIGLNVNILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 158 IIIGAMGGLNQTSLRQLLAYSSISHLGWMISSLMV----SENVWELYFIIYSLLSL--IMVILFKQMNLFFLNQIYSSTN 231
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSIcvFSIILALNVYKNLIIEFSGLSR 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 232 MKTEIKFMMFLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMRIsfsALILSYSENSW--SMT 309
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI---VKILFFQANSFllIST 319

                         330
                  ....*....|
gi 1896828160 310 NKLNKSKFIL 319
Cdd:MTH00196  320 KILKKENKIN 329
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-270 1.30e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 81.59  E-value: 1.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  24 SNSWFGVWMGLEINLLSFIPMLA-NNKNTMMNESSIKYFIVQAMASTMLLFSILLI--------------QMKYPMSWEM 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  89 ELIPSMMVSSSLLLKIGAAPFHFWFPEV-MGTSTWINCLTLMTWQKIAPMMTL-------SYCIQMSTFMFTIIILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAyEGAPTPVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 161 GAMGGLNQTSLRQLLAYSSISHLGWMISSLMV----SENVWELYFIIYSLLSLIMVILF-----KQMNLFFLNQIYSSTN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1896828160 232 MKTEIKFMMFLSLLSLGGLPPFLGFLPKWIVMQYLVENN 270
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAAS 279
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-213 2.92e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 73.13  E-value: 2.92e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  16 MGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMN-ESSIKYFIVQAMASTMLLFSILLIqmkYPMSWEMEL---- 90
Cdd:MTH00199  108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCALL---YGLTGETSIqgin 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  91 ------IPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQMSTFMFTIIILSIIIGAMG 164
Cdd:MTH00199  185 siltgdVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIG 264

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1896828160 165 GLNQTSLRQLLAYSSISHLGWMISSLMVSENVWELYFIIYSLLSLIMVI 213
Cdd:MTH00199  265 ALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIYMIIYVIMSI 313
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-330 4.54e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 66.51  E-value: 4.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   8 LLFLSTLmmGTILSISSNSWFGVWMGLEI-NLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLI-------- 78
Cdd:TIGR01770 107 LLLFALL--GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgsln 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  79 --QMKYPMSWEMELIPSM-----MVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIA---PMMTLSYCIQ--- 145
Cdd:TIGR01770 185 feDLLLFLSNGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 146 ---MSTFMFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMISSLMVS-----ENVWeLYFIIYSLLSLIMVILFKQ 217
Cdd:TIGR01770 265 seaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGtlegiKAVL-FYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 218 MNLFFLNQIYSSTNMKTEIK------FMMFLSLLSLGGLPPFLGFLPKWIVMQYLVENNMTIMMTIMVMLTTITLYYYMR 291
Cdd:TIGR01770 344 LRSYKDEWIEYISDFAGLFKtnpilaILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1896828160 292 IsfSALILSYSENSWSMTNKLNKSKfilPMTVMISTLGL 330
Cdd:TIGR01770 424 V--VKVMYFDKPERRIPSNPQSKAQ---SLLLSISALFI 457
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-187 2.62e-11

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 64.46  E-value: 2.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   8 LLFLSTLmmGTILSISSNSWFGVWMGLEINLLSFIPMLA-NNKNTMMNESSIKYFIVQAMASTMLLFSILLI-------- 78
Cdd:PRK05777  108 LVLFALL--GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLygatgsls 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  79 ------QMKYPMSWEMELIPSM-MVSSSLLLKIGAAPFHFWFPEV-----------MGTSTWINCLTLMTwqKIAPMMTL 140
Cdd:PRK05777  186 fagiakALADGSGNSLLLLFGLvFLLVGLAFKLSAVPFHMWTPDVyegaptpvtafLATAPKIAAFAVLL--RLLVVAFG 263

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1896828160 141 SYCIQMSTFMFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMI 187
Cdd:PRK05777  264 GLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLL 310
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-209 6.07e-10

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 60.13  E-value: 6.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160   8 LLFLSTLmmGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMM-NESSIKYFIVQAMASTMLLFSILLI-------- 78
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAFRRDDRRsSEAALKYFLLGALSSGFLLYGISLLygatgsln 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  79 ------QMKYPMSWEMELIPSM-MVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTL---------SY 142
Cdd:COG1007   185 lagiaaALAAGGANSPLLLLGLvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1896828160 143 CIQMSTFMFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMISSLMV-SENVWE---LYFIIYSLLSL 209
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLFMNL 335
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-187 2.71e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 58.33  E-value: 2.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  16 MGTILSISSNSWFGVWMGLEINLLSFIPM---------LANNKNTMMNESSIKYFIVQAMASTMLLFSILL--------- 77
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFGCALyfgftgneg 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  78 ----IQMKYPMSWEMEL----IPSMMVSSSLLLKIGAAPFHFWFPEVMGTSTWINCLTLMTWQKIAPMMTLSYCIQMSTF 149
Cdd:MTH00198  279 mlgtILSATLETTNIELrqgsLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1896828160 150 MFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMI 187
Cdd:MTH00198  359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-187 4.40e-06

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 48.22  E-value: 4.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  10 FLSTLMMGTILSISSNSWFGVWMGLEINLLSFIPMLANNKNTMMNESSIKYFIVQAMASTMLLFSILLIQMKY------P 83
Cdd:COG0651   112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATgtlnmaD 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  84 MSWEMELIPSMMVSSSLLL-------KIGAAPFHFWFPEVMGT-STWINCL--TLMTwqKIA---------PMMTLSYCI 144
Cdd:COG0651   192 LAARLAELDPGLLLAAFALllvgfgiKAALFPLHFWLPDAYPAaPSPVSALlsGLLT--KVGvyailrvltLLFGADPAL 269

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1896828160 145 QMSTFMFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMI 187
Cdd:COG0651   270 FLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYIL 312
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-193 2.24e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 42.78  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160  55 ESSIKYFIVQAMASTMLLFSILLIQMKYPmSWEMELIPSMMVSS--------------SLLLKIGAAPFHFWFPEVMGTS 120
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGIALLYGQYG-TLNMAYLAVKMSENptvvakialalfiaGLAMKSGAVPVHMWLPDAYPAA 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 121 -TWINCLTLMTWQ-KIAPMMTLSYCIQMSTF--------MFTIIILSIIIGAMGGLNQTSLRQLLAYSSISHLGWMISSL 190
Cdd:PRK08376  251 pSSISAMLLVIKQaGLYALARVLFSIYGPAInlatvgwvIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGL 330


                  ...
gi 1896828160 191 MVS 193
Cdd:PRK08376  331 GVG 333
PRK12650 PRK12650
DUF4040 family protein;
108-192 1.89e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 40.03  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896828160 108 PFHFWFPEVMGTSTWINC-LTLMTWQKIAPMMTLSYCIQMST------FMFTIIILSIIIGAMGGLNQTSLRQLLAYSSI 180
Cdd:PRK12650  226 PFHFWLPEAMAAITPVSAfLHAAAVVKAGIYLLLRFSPVFHDvavwnwLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305

                          90
                  ....*....|..
gi 1896828160 181 SHLGWMISSLMV 192
Cdd:PRK12650  306 SQLGWIVATIGV 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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