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Conserved domains on  [gi|1899807314|gb|QNQ16242|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Proablepharus reginae]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-218 3.91e-129

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00124:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 457  Bit Score: 372.22  E-value: 3.91e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00124  240 GYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00124  320 GLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTGLA 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 218
Cdd:MTH00124  400 TLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-218 3.91e-129

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 372.22  E-value: 3.91e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00124  240 GYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00124  320 GLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTGLA 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 218
Cdd:MTH00124  400 TLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-219 7.67e-40

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 142.91  E-value: 7.67e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIM-LATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:COG1008   256 GYGLLRFALPLFPEASAYFAPLLAaLGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVS 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:COG1008   336 HGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAAL 415

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 160 GTLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMGPF 219
Cdd:COG1008   416 GLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLLDLI 475
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-161 6.55e-39

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 136.29  E-value: 6.55e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:pfam00361 129 GYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTH 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLA-NTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:pfam00361 209 GLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGV 288


                  ..
gi 1899807314 160 GT 161
Cdd:pfam00361 289 VG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-172 1.56e-36

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 133.91  E-value: 1.56e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIM-LATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:TIGR01972 250 TYGFLRFNLPLFPDASLYFAPVLAaLGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQMIS 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:TIGR01972 330 HGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLAAL 409

                         170
                  ....*....|...
gi 1899807314 160 GTLLTATYSLHMF 172
Cdd:TIGR01972 410 GIVLAAAYMLTLY 422
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-218 3.91e-129

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 372.22  E-value: 3.91e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00124  240 GYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00124  320 GLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTGLA 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 218
Cdd:MTH00124  400 TLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-219 9.97e-121

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 351.14  E-value: 9.97e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00068  240 GYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALIQTPWSFSGAIILMISH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00068  320 GLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMVSLFNWSNWTILITGLG 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMGPF 219
Cdd:MTH00068  400 TLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELISGMF 458
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-218 2.13e-113

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 332.24  E-value: 2.13e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00110  240 GYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMGATALMIAH 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00110  320 GLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIMSSFSWSNITIILMGLN 399

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 218
Cdd:MTH00110  400 MLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKIILGP 457
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-217 8.18e-94

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 282.61  E-value: 8.18e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00127  241 GYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMIAH 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00127  321 GLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTGLG 400

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMG 217
Cdd:MTH00127  401 TLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWG 457
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-215 3.67e-86

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 262.57  E-value: 3.67e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00206  236 GYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKGALLLMIAH 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00206  316 GLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNFTLPLLGLG 395

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALI 215
Cdd:MTH00206  396 FLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-216 8.32e-73

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 228.32  E-value: 8.32e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLN-PLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:MTH00044  241 GYGLIRLINLFSlPSANNISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIFSGTNWGINGALILMIA 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:MTH00044  321 HGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLIISSIISWSILSFPIIGL 400

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1899807314 160 GTLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIM 216
Cdd:MTH00044  401 ATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNIIL 457
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-216 3.26e-65

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 208.47  E-value: 3.26e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00163  228 GYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMGSLLMMIGH 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00163  308 GLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKLSMIFLMLL 387

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIM 216
Cdd:MTH00163  388 SFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLFM 443
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-217 4.27e-60

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 194.29  E-value: 4.27e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00150  199 GYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSNTSWGWVGALIMMVSH 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00150  279 GFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIMIFPSLISYSPWFFVPLGLM 358

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMG 217
Cdd:MTH00150  359 VFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLLFM 415
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-215 4.51e-54

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 179.94  E-value: 4.51e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00014  234 GYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSNTSWGWQGALAMMIAH 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00014  314 GLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLSTAILLAIT 393

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALI 215
Cdd:MTH00014  394 SFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLI 448
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-216 2.68e-53

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 177.48  E-value: 2.68e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00205  232 GYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNGAIIMMVAH 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00205  312 GLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKISGIPLSLI 391

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIM 216
Cdd:MTH00205  392 SFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKIFI 447
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-219 7.67e-40

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 142.91  E-value: 7.67e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIM-LATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:COG1008   256 GYGLLRFALPLFPEASAYFAPLLAaLGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVS 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:COG1008   336 HGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAAL 415

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 160 GTLLTATYSLHMFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLLMKPALIMGPF 219
Cdd:COG1008   416 GLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLLDLI 475
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-161 6.55e-39

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 136.29  E-value: 6.55e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:pfam00361 129 GYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTH 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLA-NTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:pfam00361 209 GLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGV 288


                  ..
gi 1899807314 160 GT 161
Cdd:pfam00361 289 VG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-172 1.56e-36

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 133.91  E-value: 1.56e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIM-LATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:TIGR01972 250 TYGFLRFNLPLFPDASLYFAPVLAaLGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQMIS 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:TIGR01972 330 HGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLAAL 409

                         170
                  ....*....|...
gi 1899807314 160 GTLLTATYSLHMF 172
Cdd:TIGR01972 410 GIVLAAAYMLTLY 422
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-173 6.22e-32

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 121.46  E-value: 6.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIM-LATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:PRK05846  258 AYGLLRFSLPLFPDASHEFAPIIItLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIFAGNQLGIQGAIFQMIS 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:PRK05846  338 HGLSSAALFLLVGVLYDRLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLILLGSFQVNPVIAFIATT 417

                         170
                  ....*....|....
gi 1899807314 160 GTLLTATYSLHMFL 173
Cdd:PRK05846  418 GLILAAVYSLWLYQ 431
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-172 1.45e-31

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 120.16  E-value: 1.45e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIM-LATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:MTH00217  253 GYGFIRFSWPLLPEASEYFSPLIQtLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIFSHTIQGLVAAIFLMLA 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:MTH00217  333 HGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSLLAAFEYSYIVGVLASL 412

                         170
                  ....*....|...
gi 1899807314 160 GTLLTATYSLHMF 172
Cdd:MTH00217  413 GMVLSAGYSIYLY 425
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-172 1.76e-31

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 120.17  E-value: 1.76e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFI-MLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:MTH00204  256 GYGFLRFSWPLFPAASEYFAPLIvMLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLFTHTIEGLVAAVFLMLA 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:MTH00204  336 HGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSLLAAFEYSLGLGVLVTS 415

                         170
                  ....*....|...
gi 1899807314 160 GTLLTATYSLHMF 172
Cdd:MTH00204  416 GMVWSAAYSLYLY 428
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-216 1.88e-29

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 114.63  E-value: 1.88e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYP-FIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:MTH00226  277 GYGLVRLSWPILPLGAQNLAPaVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGSIFIMLA 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:MTH00226  357 HGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSILSSFNWNPIIGVFVCS 436

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807314 160 GTLLTATYSLHmFLTTQRNKLPTNINNTWPTQTREHLLMTLHIVPMALLL-MKPALIM 216
Cdd:MTH00226  437 GVILSAVYSFY-FANRVTFGAPGNLITFARDVNRREFYITASMVFFAFLIgIYPIFIL 493
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-176 7.66e-21

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 89.82  E-value: 7.66e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRITPMLNPLSTKLYYPFIML--ATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:COG0651   253 YAILRVLTLLFGADPALFLGTLLLvlGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLN 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFN-WSPLTIIMTG 158
Cdd:COG0651   333 HALAKALLFLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEaGAWLLAAVLL 412

                         170
                  ....*....|....*...
gi 1899807314 159 LGTLLTATYSLHMFLTTQ 176
Cdd:COG0651   413 LSSLLTLAYFVRIFGRAQ 430
ndhD CHL00011
NADH dehydrogenase subunit 4
 1-171 7.42e-20

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 87.69  E-value: 7.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYPFIML-ATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:CHL00011  258 AYGLIRINMELLPHAHSIFSPWLVIvGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAILQIIS 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERThsRTMLLAR--GLQLILPLMTTWWLLANLMNMALPPTINLTGELL----IITS---LFNWS 150
Cdd:CHL00011  338 HGFIGAALFFLAGTSYDRI--RLVYLDEmgGIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIvffgIITSqkyLLMPK 415

                         170       180
                  ....*....|....*....|.
gi 1899807314 151 PLTIIMTGLGTLLTATYSLHM 171
Cdd:CHL00011  416 ILITFVMAIGMILTPIYLLSM 436
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
25-203 8.36e-20

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 87.45  E-value: 8.36e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  25 LATWGIIMT---SSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSR 101
Cdd:PRK06473  274 LATWAVVSVlygASCAIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILAAVFQMISHGLISALLFLLVGVVYKKTGSR 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 102 TMLLARGL---QLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLGTLLTATYSLHMF------ 172
Cdd:PRK06473  354 DVDVLRGLlnpERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGSFPIFPVQTLLCMIGTGLTAVYFLLLVnrvffg 433

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1899807314 173 -LTTQRNKLPtniNNTWPTQTREHLLMTLHIV 203
Cdd:PRK06473  434 rLTAELSNLP---RVLWSERLPALVLAVLIVV 462
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-181 3.49e-18

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 82.77  E-value: 3.49e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRIT-PMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:PRK12561  232 GYALIRFNvQMLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGIAAFTDLGISGAMLQMIS 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLI---ITSLFNWSPL---- 152
Cdd:PRK12561  312 HGLIAAALFFLTGVTYERTHTLSIPNMGGLAKVMPKTFALFTASSMASLALPGMSGFVSELTVflgITSSDVYSSTfrti 391

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1899807314 153 TIIMTGLGTLLTATYSLHM----FLTTQRNKLP 181
Cdd:PRK12561  392 TILLAAVGLILTPIYLLSMlrrvFYGPRSELLP 424
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 1-186 1.70e-17

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 80.34  E-value: 1.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRItpmLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAH 80
Cdd:MTH00094  198 TAGFLRI---LGSLNFVYNNFWIIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGLMMMLAH 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLG 160
Cdd:MTH00094  275 GYTSTLMFYLIGEFYHISKSRLIYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSFFFIFFY 354

                         170       180
                  ....*....|....*....|....*.
gi 1899807314 161 TLLTATYSLHMFLTTQRNKLPTNINN 186
Cdd:MTH00094  355 FLVSFYYSLFLIVSSFMGKKFSNFNN 380
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-171 1.98e-15

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 74.74  E-value: 1.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   1 GYGIIRITPMLNPLSTKLYYP-FIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:PRK02546  260 GYALLRMNAGMLPDAHAQFAPlLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGTSGAMLQMIS 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  80 HGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLII----TSLFNWSPLTII 155
Cdd:PRK02546  340 HGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAMWTACSLASLALPGMSGFVAELMVFvgfaTSDAYTLPFRVV 419

                         170
                  ....*....|....*....
gi 1899807314 156 MTGL---GTLLTATYSLHM 171
Cdd:PRK02546  420 VVFLaavGVILTPIYLLSM 438
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
2-167 1.71e-13

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 68.97  E-value: 1.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRITPMLNPLSTKLYYPfiMLATWG---IIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMI 78
Cdd:PRK07363  253 YGLLRFGLQLFPQTWSLVAP--GLAIIGtisVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLLGAVAQMI 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  79 AHGLTSSLLFCLANTNYERTHSRTMLLARGLQLI---LPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTII 155
Cdd:PRK07363  331 SHGLILALLFHLVGIVERKVGTRDLDVLNGLMNPirgLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFSTFPIPTL 410

                         170
                  ....*....|..
gi 1899807314 156 MTGLGTLLTATY 167
Cdd:PRK07363  411 LCIVASGLTAVY 422
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-167 3.75e-13

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 67.98  E-value: 3.75e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRIT----PMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALM 77
Cdd:PRK08375  250 YALIRIYftvfGGDFRFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHL 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  78 IAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLF---NWSPLTI 154
Cdd:PRK08375  330 LHHALMKGALFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVeagQWLVLAV 409

                         170
                  ....*....|...
gi 1899807314 155 IMtgLGTLLTATY 167
Cdd:PRK08375  410 LL--ASSLLALLY 420
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-209 1.38e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 66.53  E-value: 1.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRI-------TPMLNPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 74
Cdd:PRK12667  271 YAIIRFlytifgiSPSLIDFRAALSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAAL 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  75 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSP-LT 153
Cdd:PRK12667  351 FHIINHAIAKSLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFyLP 430

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1899807314 154 IIMTGLGTLLTATYSLHMFLTTQRNKLPTNINntwpTQTREHLLMTLHIVPMALLL 209
Cdd:PRK12667  431 ALVLLIASAISLVGYFRAWYSLFFGKPKSGEE----VEHKESPSMSVVILVLALAV 482
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 38-217 3.37e-12

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 65.34  E-value: 3.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  38 LRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMT 117
Cdd:PRK06458  300 LRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHSLTKSAIFFASGNVLQKYGTRDINVIRGLLKVSPLTG 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 118 TWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLGTLLTATYSLHMFLTTQrnklptnINNTWPTQTREHLL 197
Cdd:PRK06458  380 WGLMLGALAIAGMPPFGVFISEFLILTAGLARGPLLIAILLLLLLTLAFAALVRRVAGM-------VFGEPPEAVNRGDL 452

                         170       180
                  ....*....|....*....|
gi 1899807314 198 MTLHIVPMALLLMKPaLIMG 217
Cdd:PRK06458  453 GWLTTSPMFVHLVLV-LVLG 471
PRK12650 PRK12650
DUF4040 family protein;
31-169 9.53e-12

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 63.91  E-value: 9.53e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  31 IMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQ 110
Cdd:PRK12650  284 LMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRDIRRLGSLW 363

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1899807314 111 LILPLMTTWWLLANLMNMALPPTINLTGELLIITSLF-----NWSP-LTIIMTGLGTLLTATYSL 169
Cdd:PRK12650  364 RRMPFTFVSVTIAALSMAAVPPLFGFVSKEGMLTAFLeapggNAGVvLLLVGAALGAVFTFAYSA 428
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 38-162 5.62e-11

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 61.86  E-value: 5.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  38 LRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMT 117
Cdd:PRK12647  278 VRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFLVAHSLYKGALFMVAGIIDHETGTRDITKLGGLRRAMPITA 357

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1899807314 118 TWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLGTL 162
Cdd:PRK12647  358 AAALLAALSMAGLPPLFGFLAKELIYEALLEAPLWSLILTVAAVL 402
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 31-175 2.54e-10

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 59.78  E-value: 2.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  31 IMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQtpwSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQ 110
Cdd:COG1009   287 LFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG---AYVAALFHLLTHAFFKALLFLGAGSVIHATGTRDIRKMGGLR 363

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807314 111 LILPLMTTWWLLANLMNMALPPTINLTGELLIITSLF---NWSPLTIIMTGLGTLLTATYSLHMFLTT 175
Cdd:COG1009   364 KKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALeagGLGPLLLAVALLGAFLTAFYSFRLFFLV 431
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 23-197 2.80e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 50.59  E-value: 2.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  23 IMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRT 102
Cdd:PRK06589  284 IFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQ 363

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 103 MLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWS--PLTIIMTGLGTLLTATYSLHMFLTTQRNKL 180
Cdd:PRK06589  364 VDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNqpWLSIIVMLVVIASSILSALYLLKILSSIYK 443

                         170
                  ....*....|....*..
gi 1899807314 181 PTNINNTWPTQTREHLL 197
Cdd:PRK06589  444 PSLSENSFITKSLPYLM 460
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 2-147 4.92e-07

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 49.73  E-value: 4.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRItpMLNPLSTKLYYPFIML------ATWGIIMTssicLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTG--A 73
Cdd:PRK08667  253 YGLVRF--LMDVLSPELWWGVLILlagsisALLGVIYA----LKEHDLKGLLAYSSIENIGIILMGIGLYVIFGVYGldT 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  74 MALM---------IAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIIT 144
Cdd:PRK08667  327 LALLalggalfhsLNHALFKSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFASELLLYE 406


                  ...
gi 1899807314 145 SLF 147
Cdd:PRK08667  407 SFF 409
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 2-169 1.10e-06

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 48.77  E-value: 1.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRITPMLNPLSTkLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHG 81
Cdd:PRK12644  251 YLVARLAPGFADVPV-WRPTVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLAMLLAHA 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  82 LTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLAnLMNMA-LPPTINLTGELLIITSLFN------WSPLTI 154
Cdd:PRK12644  330 LFKAALFLVVGIIDHSTGTRDIRKLSGLGRRQPVLAVVAALA-AASMAgLPPLLGFVAKEAALEAVLHdgalgpAGPVVL 408

                         170
                  ....*....|....*
gi 1899807314 155 IMTGLGTLLTATYSL 169
Cdd:PRK12644  409 AGIVLGSILTVAYSL 423
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 23-159 2.08e-06

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 47.84  E-value: 2.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  23 IMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRT 102
Cdd:PRK08377  277 IIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVDAGVFHMINHAIVKALLFLAVGYVGITLGGTE 356

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1899807314 103 MLLARGLQLILPLMTTWWLLANLMNMALPptinltgelliitsLFN--WSPLTIIMTGL 159
Cdd:PRK08377  357 IEKFEGLGKRMPLTALALTIGALSTVGIP--------------LFNvfWSKFRIILAGL 401
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-164 2.19e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 47.78  E-value: 2.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRI-----TPMLNPLStkLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVI------AATLIQTPWSL 70
Cdd:PRK08376  267 YALARVlfsiyGPAINLAT--VGWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLlglgvgLAALGDPAMAS 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  71 TGAMAL------MIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIIT 144
Cdd:PRK08376  345 YGEIALaggiyhIVNHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYE 424

                         170       180
                  ....*....|....*....|
gi 1899807314 145 SLFNWSPLTIIMTGLGTLLT 164
Cdd:PRK08376  425 SSALFNPILGVIAMIGSVLT 444
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 2-88 2.60e-06

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 47.44  E-value: 2.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRITPML--NPLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIA 79
Cdd:PRK08676  254 YGILRLSALLrqSGAAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLA 333


                  ....*....
gi 1899807314  80 HGLTSSLLF 88
Cdd:PRK08676  334 HSLVKSGLF 342
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 22-134 2.61e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 47.81  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  22 FIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANT---NYERT 98
Cdd:PRK12662  282 FMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSisyHFGTT 361

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1899807314  99 HSRTMLlarGLQLILPLMTTWWLLANLMNMALPPTI 134
Cdd:PRK12662  362 KLEDCL---NLWKSMPKITLAFVLLSLSLIGMPPTS 394
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 20-208 4.94e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 46.91  E-value: 4.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  20 YPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTH 99
Cdd:PRK08668  273 YILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVIYRTG 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 100 SRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLF-NWSPLTIIMTGLGTLLTATYSLHMFLTTQRN 178
Cdd:PRK08668  353 TTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALIsKGMPITAFMAFFGSIGSFLYVFRPLAGVFLG 432

                         170       180       190
                  ....*....|....*....|....*....|
gi 1899807314 179 KLPTNINNtwptqTREHLLMTLhiVPMALL 208
Cdd:PRK08668  433 QLPSDHKD-----VKEAPLPML--IPMAIL 455
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 38-148 1.23e-05

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 45.49  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  38 LRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLF-CLANTNYERTHSRTMLLARGLQLILPLM 116
Cdd:COG1007   288 LAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFaVILLLSRKGGEAEEIEDLAGLARRSPLL 367

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1899807314 117 TtwWLLANLM-NMA-LPPTINLTGELLIITSLFN 148
Cdd:COG1007   368 A--LAMTIFLlSLAgIPPTAGFFGKFYVFSAAVE 399
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
38-84 1.41e-05

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 45.20  E-value: 1.41e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1899807314  38 LRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTS 84
Cdd:PRK05777  289 LSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMT 335
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 40-163 1.69e-05

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 44.97  E-value: 1.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  40 QTDLKSLIAYSSVSHMGLV---IAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLM 116
Cdd:PRK06525  293 QQDMKRLLAYSTITQLGYMffgLSLAILGSRLALEGSIAYIFNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLV 372

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1899807314 117 TTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGLGTLL 163
Cdd:PRK06525  373 GVGFCVAALAITGVPPFNGFFSKFPIFAAGFELSVEYWILLPAMVLL 419
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 4-175 2.71e-05

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 44.76  E-value: 2.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   4 IIRITPMLNplSTKLYYPFIML-ATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPwslTGAMALMIAHGL 82
Cdd:MTH00207  229 LIRFYPFLS--STYWFNPALLLtASLTMLMAGLSAMTECDMKKIIALSTLSQLGVMMASLGLGMP---KLALFHLITHAL 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  83 TSSLLFCLANTN-YERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITS--LFNWSPLTIIMTGL 159
Cdd:MTH00207  304 FKALLFVCAGSLiHSHHHSQDLRTMGNLTNQMPLTTSCLLIANLALCGSPFLSGFYSKDLILESslFYPHNSLMILMIFL 383

                         170
                  ....*....|....*.
gi 1899807314 160 GTLLTATYSLHMFLTT 175
Cdd:MTH00207  384 ATALTAAYSTRFTLAV 399
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-161 3.17e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 44.17  E-value: 3.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRITPMLNplstKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIqtpwsltgAMALMIAHG 81
Cdd:PRK07234  232 FPLVRCALDVP----GLDLIVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQLGFILAAPLV--------GGLYALAHG 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  82 LTSSLLFCLANTNYERTHS--RTMLLARGLQLILplmttwwLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTGL 159
Cdd:PRK07234  300 LVKSTLFLCAGALPSRNFTelISQMLGIGKWIPL-------TMASFSIAGFPLLAGFVSKVLTLKNLLPWQAIALNLAAV 372


                  ..
gi 1899807314 160 GT 161
Cdd:PRK07234  373 GT 374
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
23-156 1.88e-04

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 41.94  E-value: 1.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  23 IMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRT 102
Cdd:PRK06277  270 IALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTSN 349

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1899807314 103 MLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLF--NWSPLTIIM 156
Cdd:PRK06277  350 LRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMqaNMPELAIIM 405
PRK12646 PRK12646
DUF4040 family protein;
2-171 2.36e-04

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 41.66  E-value: 2.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRITPMLNpLSTKLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLV-----IAATLIQTP--------- 67
Cdd:PRK12646  258 FLLFRFTPLLG-LSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMImamvgIGGGYAQHQqdaiasiyv 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  68 WSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLAnLMNMALPPTIN--LTGELLiITS 145
Cdd:PRK12646  337 FVLFAALFHLMNHAIFKCALFMGVGIIDHEAGTRDIRILSGMRQLFPKMNLVMTIA-ALSMAGVPFLNgfLSKEMF-LDA 414

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1899807314 146 LFNWSPL-------TIIMTGLG---TLLTATYSLHM 171
Cdd:PRK12646  415 LTQTGQLsqfslisMIIIVFIGviaSIFTFTYALYM 450
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 9-173 4.54e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 40.64  E-value: 4.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   9 PMLNPLSTkLYYPFIMLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIqTPWSLTgaMALMIAHGLTSSLLF 88
Cdd:MTH00144  135 SNFLDLYW-LAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILH-GSWLMW--MYFLIYIVSSGFLFF 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  89 CLANTNYERTHSRTMLLARglqlilPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTIIMTG-LGTLLTATY 167
Cdd:MTH00144  211 SLWSGDSGSMKDLGSLKPS------YKTGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLlLGSLISLFF 284


                  ....*.
gi 1899807314 168 SLHMFL 173
Cdd:MTH00144  285 YLSVFF 290
ND5 MTH00209
NADH dehydrogenase subunit 5; Provisional
 2-171 9.08e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177252 [Multi-domain]  Cd Length: 564  Bit Score: 40.01  E-value: 9.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   2 YGIIRITPMLNplSTKLYYPFIMLA-TWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPwslTGAMALMIAH 80
Cdd:MTH00209  223 YLLIRFFPSLF--SSPFFSMSLLLLgSLTTLMASMSANVESDLKKIIALSTLSQLGLMMCSLGLNQP---ELAFFHLITH 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  81 GLTSSLLF-CLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLF--NWSPLTIIMT 157
Cdd:MTH00209  298 ALFKALLFiCAGNIIHSHGHSQDIRMVGNLWYQMPITSICLNIANLSLCGIPFLAGFYSKDLILESMLesNMPIMTLILM 377

                         170
                  ....*....|....
gi 1899807314 158 GLGTLLTATYSLHM 171
Cdd:MTH00209  378 FLSTSLTAAYSMRL 391
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 3-155 1.19e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 39.52  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314   3 GIIRITPMLNPLSTKLYYPFIMLATWGIIMTSSICLrqtDLKSLIAYSSVSHMgLVIAATLIQTPWSLTG-AMALMIAHG 81
Cdd:MTH00062  214 GVYRFCGFIFSGSFLGYLFLCCLFSVFFLITACSEL---DGKRWLAFLSLSHI-LVPVLGLFVGDWSSINlSFFYCLGHG 289

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1899807314  82 LTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLFNWSPLTII 155
Cdd:MTH00062  290 LSAGLVFLLLWCFYEVSGSRNWVLLKSGINGSLVLRVIVVFSFLSLCSFPPTIQFFCEVFLVSSSFGVLVYLLF 363
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 24-157 2.01e-03

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 38.61  E-value: 2.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  24 MLATWGIIMTSSICLRQTDLKSLIAYSSVSHMGLViaaTLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTM 103
Cdd:MTH00011  152 SMAAMSALAGGLGGMNQTQLRPLLAYSSIGHMGWM---TMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSK 228

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1899807314 104 LLArglqliLPLMTTWWLLANLMNMA-LPPTINLTGELLIITSLFNWSPLTIIMT 157
Cdd:MTH00011  229 ISS------MSQTTSMSLFIMLLSLGgLPPFTGFMPKLMAIETLTSNSMILILLV 277
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 38-219 5.15e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 37.26  E-value: 5.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  38 LRQTDLKSLIAYSSVSHMGLVIAATLIQtpwSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGlqlilPLMT 117
Cdd:MTH00200  170 LNQTQLRKILAYSSIAHLGWLLSGLVYS---PNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKN-----PILS 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 118 TWWLLANLMNMALPPTINLTGELLIITSLFNWS-PLTIIMTGLGTLLTATYSLHMFLTTQRNKLPTNINN--TWPTQTRE 194
Cdd:MTH00200  242 MLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGlFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMmsSWRTKSNS 321

                         170       180
                  ....*....|....*....|....*.
gi 1899807314 195 HLLMTLHIV-PMALLLMKPALIMGPF 219
Cdd:MTH00200  322 NLLVGLLLLlSILGLPLTPQLLFLFF 347
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 38-147 7.16e-03

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 37.18  E-value: 7.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  38 LRQTDLKSLIAYSSVSHMGLVI----------------AATLiqtpwSLTGAMALMIAHGLTSSLLFCLANTNYERTHSR 101
Cdd:PRK06521  295 LAEHDLKRLLAYSTIENIGIIFvglglamvfiaygmplLAAL-----ALTAALYHLLNHALFKSLLFLGAGAVLHATGTR 369

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1899807314 102 TMLLARGLQLILPLMTTWWLLANLMNMALPPTINLTGELLIITSLF 147
Cdd:PRK06521  370 DMEKLGGLIRRMPWTAWAFLIGCLAISALPPLNGFVSEWLLLQSLL 415
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 30-216 9.36e-03

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 36.85  E-value: 9.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314  30 IIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTS----SLLFCLANTNYERTHSrtMLL 105
Cdd:TIGR01770 280 MLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMSlgafGVLSLLRSYKDEWIEY--ISD 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807314 106 ARGLQLILPLMTTWWLLaNLMNMA-LPPTINLTGELLIITSLFN-----WSPLTIIMTGLGTLLTATYSLHMFLttqrNK 179
Cdd:TIGR01770 358 FAGLFKTNPILAILILI-FMFSLAgIPPLAGFFGKFYVFFALLKsglywLAVIAVLTSVIGAFYYLRVVKVMYF----DK 432

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1899807314 180 LPTNINNTWPTQTREHLLMTLHIVpMALLLMKPALIM 216
Cdd:TIGR01770 433 PERRIPSNPQSKAQSLLLSISALF-ILFLGLFPSLIL 468
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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