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Conserved domains on  [gi|1917171646|gb|QOL11851|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Grallaria rufocinerea]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.52e-154

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 437.33  E-value: 1.52e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPNSVNYMKLWQTNKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 1917171646 321 VNTLTTALMTLTLMLLPLSPMTFTTI 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.52e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 437.33  E-value: 1.52e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPNSVNYMKLWQTNKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 1917171646 321 VNTLTTALMTLTLMLLPLSPMTFTTI 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-298 2.79e-27

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 111.36  E-value: 2.79e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  14 TLGTTITISSNHWMMAWTGLEINTLAILPLIS-KPHHPRAIEATTKYFLVQAAASTLLLF-SSMTNAwFTGQWDITQLTH 91
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  92 PTS------------CLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPP-------ITLLLLTSHSLNPI 152
Cdd:COG1007   191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfaallrlLVEAFPGLAADWQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 153 LLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTL--LTFYL--YCLMTAAIFFTL-----NTTK 223
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVIlllsrKGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1917171646 224 ALKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAY 298
Cdd:COG1007   351 AEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 5.08e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 99.70  E-value: 5.08e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  23 SNHWMMAWTGLEINTLAILPLI-SKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  91 HPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNP------ILLTLMAITSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPsspfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 165 GGWAGLNQTQIRKILAFSSISHLGWMAVIL----TYNPKLTLLTFYLYCLMTAAIF-----FTLNTTKALKLSTMMTAWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1917171646 236 KIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-297 8.30e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 98.87  E-value: 8.30e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  14 TLGTTITISSNHWMMAWTGLEINTLAILPLIS-KPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  93 TSC------------LLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPP-------ITLLLLTSHSLNPIL 153
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavflrlFLYILFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 154 LTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTL--LTFYL--YCLMTAAIFFTL------NTTK 223
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYIfiYALMSLGAFGVLsllrsyKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1917171646 224 ALKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLA 297
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.52e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 437.33  E-value: 1.52e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPNSVNYMKLWQTNKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 1917171646 321 VNTLTTALMTLTLMLLPLSPMTFTTI 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-320 1.21e-128

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 371.83  E-value: 1.21e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSlNPILLTLMAIT 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPNSVNYMKLWQTNKP 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-322 1.62e-124

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 361.16  E-value: 1.62e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPNSVNYMKLWQTNKP 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                  ..
gi 1917171646 321 VN 322
Cdd:MTH00070  321 TN 322
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-316 2.46e-107

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 317.56  E-value: 2.46e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPnSVNYMKL-WQ 316
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKMkWQ 316
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-317 1.64e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 282.24  E-value: 1.64e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPNSVNYMKLWQT 317
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRT 317
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 7-322 2.54e-79

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 246.00  E-value: 2.54e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   7 LISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDI 86
Cdd:MTH00041    7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  87 TQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAITSAALGG 166
Cdd:MTH00041   87 NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGG 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 167 WAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSLTATLML 246
Cdd:MTH00041  167 WGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFIL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1917171646 247 TLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITL-PPNSVNYMKlWQTNKPVN 322
Cdd:MTH00041  247 SILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLfPQHSISLFS-WRNSGNIT 322
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-319 1.14e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 184.64  E-value: 1.14e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGqwditqLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLnpiLLTLMAIT 160
Cdd:MTH00160   82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN---FIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 161 SAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSL 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1917171646 241 TATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCAtITLPPNSVNYMKLWQTNK 319
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSS-LMLNYNKNKWNLKKKKNK 310
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-302 8.79e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 163.90  E-value: 8.79e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWF 80
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  81 TGQWDITqlthptscLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPI-LLTLMAI 159
Cdd:MTH00144   81 SFSWFSM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAyLLCVISV 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 160 TSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNtTKALKLSTMMTAWTKIPS 239
Cdd:MTH00144  153 LSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLW-SGDSGSMKDLGSLKPSYK 231

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1917171646 240 LTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATI 302
Cdd:MTH00144  232 TGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 12-310 6.64e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 159.17  E-value: 6.64e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  12 SLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSsMTNAWFTgqwdITQLTH 91
Cdd:MTH00011   14 TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLG-MTMMWSF----PSLLKN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  92 PTScLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAITSAALGGWAGLN 171
Cdd:MTH00011   89 ITA-LMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMN 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 172 QTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSLTATLMLTLLSL 251
Cdd:MTH00011  168 QTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSL 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1917171646 252 AGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYcATITLPPNSVN 310
Cdd:MTH00011  248 GGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-298 6.58e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 140.58  E-value: 6.58e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  12 SLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMtnAWFTGQWditqlTH 91
Cdd:MTH00197    6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS--LSFSNLY-----LS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  92 PTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHslNPILLTLMAITSAALGGWAGLN 171
Cdd:MTH00197   79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGIGGMN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 172 QTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLMTAAIFFTLNTTKALKLSTMMTAWTKIPSLTATLMLTLLSL 251
Cdd:MTH00197  157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1917171646 252 AGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAY 298
Cdd:MTH00197  237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-298 2.79e-27

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 111.36  E-value: 2.79e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  14 TLGTTITISSNHWMMAWTGLEINTLAILPLIS-KPHHPRAIEATTKYFLVQAAASTLLLF-SSMTNAwFTGQWDITQLTH 91
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  92 PTS------------CLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPP-------ITLLLLTSHSLNPI 152
Cdd:COG1007   191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfaallrlLVEAFPGLAADWQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 153 LLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTL--LTFYL--YCLMTAAIFFTL-----NTTK 223
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVIlllsrKGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1917171646 224 ALKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAY 298
Cdd:COG1007   351 AEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-296 6.94e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 103.57  E-value: 6.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  13 LTLGTTITISSNHWMMAWTGLEINTLAILPLI-SKPHHPRAIEATTKYFLVQAAASTLLLFS-------------SMTNA 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  79 WFTGQWDITQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNpiLLTLMA 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 159 ITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNP----KLTLLTFYLYCLMTAAIF---FTLNTTKALkLSTMM 231
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFsiiLALNVYKNL-IIEFS 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1917171646 232 TAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRL 296
Cdd:MTH00196  239 GLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 5.08e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 99.70  E-value: 5.08e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  23 SNHWMMAWTGLEINTLAILPLI-SKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  91 HPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNP------ILLTLMAITSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPsspfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 165 GGWAGLNQTQIRKILAFSSISHLGWMAVIL----TYNPKLTLLTFYLYCLMTAAIF-----FTLNTTKALKLSTMMTAWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1917171646 236 KIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-296 7.28e-24

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 101.82  E-value: 7.28e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  14 TLGTTITISSNHWMMAWTGLEINTLAILPLIS-KPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDITQLTHP 92
Cdd:PRK05777  113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  93 TS------------CLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPP-------ITLLLLTSHSLNPIL 153
Cdd:PRK05777  193 LAdgsgnsllllfgLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfavllrlLVVAFGGLSEDWQQV 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 154 LTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWM--AVILTYNPKLTLLTFYL--YCLMTAAIF-FTLNTTKALKLS 228
Cdd:PRK05777  273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvGLAAGTAEGYSAVLFYLlaYLFMTLGAFgVISLLRRKGGEA 352

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1917171646 229 TMMTAWTKI----PSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRL 296
Cdd:PRK05777  353 ESISDFAGLskrsPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-297 8.30e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 98.87  E-value: 8.30e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  14 TLGTTITISSNHWMMAWTGLEINTLAILPLIS-KPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  93 TSC------------LLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPP-------ITLLLLTSHSLNPIL 153
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavflrlFLYILFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 154 LTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTL--LTFYL--YCLMTAAIFFTL------NTTK 223
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYIfiYALMSLGAFGVLsllrsyKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1917171646 224 ALKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLA 297
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 10-296 1.09e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 98.17  E-value: 1.09e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  10 IMSLTLGTTITISSNHWMMAWTGLEINTLAILPLIS-KPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDI-- 86
Cdd:MTH00199  103 ILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqg 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  87 --TQLTHPTSCLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTlmAITSAAL 164
Cdd:MTH00199  183 inSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIY 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 165 GGWAGLNQTQIRKILAFSSISHLGWMAVILTYNP----KLTLLTFYLYCLMTAAIFF---TLNTTKALkLSTMMTAWTKI 237
Cdd:MTH00199  261 GAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSICSFSiilSLKLTKGL-IVEVSGLSRKN 339

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1917171646 238 PSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRL 296
Cdd:MTH00199  340 PVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-296 1.03e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 83.66  E-value: 1.03e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  30 WTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDITQLTH----------PTSCLLLT 99
Cdd:COG0651   133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAArlaeldpgllLAAFALLL 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 100 AAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAM---------KLPPITLLLLTSHSLNPILLTLmAITSAALGGWAGL 170
Cdd:COG0651   213 VGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtkvgvyailRVLTLLFGADPALFLGTLLLVL-GLLTMLVGALGAL 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 171 NQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYC----LMTAAIFFT----LNTTKALKLSTMMTAWTKIPSLTA 242
Cdd:COG0651   292 AQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFLAagaiERATGTRDLDKLGGLGKRMPLTAA 371

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1917171646 243 TLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRL 296
Cdd:COG0651   372 AFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-302 2.33e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 76.82  E-value: 2.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   3 PQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAI---------EATTKYFLVQAAASTLLLFS 73
Cdd:MTH00198  187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFG 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  74 SMTNAWFTGQ----WDITQLTHPTS----------CLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPI 139
Cdd:MTH00198  267 CALYFGFTGNegmlGTILSATLETTnielrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVY 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 140 TLLLLTSHSLNpiLLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVIL---TYNPKLTLLTFYLYCLMTAAIF 216
Cdd:MTH00198  347 ILLTSLVITSK--LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVsagTYESLQASWTYAVTYLVSALAS 424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 217 FTL----------------------NTTKALKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQE 274
Cdd:MTH00198  425 FTVictleefgtrtptsrqrdgsfgNYNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIA 504

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1917171646 275 MTPTATIIALLSLLGL-------FFYLRLAycATI 302
Cdd:MTH00198  505 FSSSLSIYYLVALFAIictcisaFYYIRIV--ATI 537
ndhB CHL00049
NADH dehydrogenase subunit 2
 1-296 9.01e-11

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 62.71  E-value: 9.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   1 MSPQAKLISIMSLTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHP-RAIEATTKYFLVQAAASTLLL--FSsmtn 77
Cdd:CHL00049  108 MAITEFLLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFS---- 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  78 aWFTGQ-------WDI------TQLTHPTSCLL----LTAAISMKLGLAPFHFWFPEVLQGS-----------SLTTGLL 129
Cdd:CHL00049  184 -WLYGLsggeielQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSptpvvaflsvtSKVAASA 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 130 LATAMklppITLLLLTSHSLNPILLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAV-ILTYNPK------LTL 202
Cdd:CHL00049  263 LATRI----FDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIgIIVGDSNdgyasmITY 338

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 203 LTFYLYCLMTA---AIFFTLNT-TKALKLSTMMtaWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPT 278
Cdd:CHL00049  339 MLFYIFMNLGTfacIVLFGLRTgTDNIRDYAGL--YTKDPFLALSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFL 416

                         330
                  ....*....|....*...
gi 1917171646 279 ATIIALLSLLGLFFYLRL 296
Cdd:CHL00049  417 VSIGLLTSVISIYYYLKI 434
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-310 1.01e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 56.43  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  33 LEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFS-SMTNAwFTGQWDITQLTH--PTSCLLLTA------AIS 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAGalAENPTVVTAfgfvllALA 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 104 MKLGLAPFHFWFPEVLQG-SSLTTGLLLATAMK----------LPPITLLLLTSHSLNPILLTLMAITSAAlGGWAGLNQ 172
Cdd:PRK08375  214 LKAAVFPLHTWLPRAYPAaPPVVTALLSGLVTKvavyaliriyFTVFGGDFRFALGLGWLLAVLALLSMLV-GSLAALGQ 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 173 TQIRKILAFSSISHLGWMAVILTYNPKLTLL--TFYL--YCLMTAAIFFTLN----TTKALKLSTMMTAWTKIPSLTATL 244
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAagLLHLlhHALMKGALFLAAGaievTYGTRRLSELSGLGRRMPLTAAAF 372

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1917171646 245 MLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAYCATITLPPNSVN 310
Cdd:PRK08375  373 AVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPPGSE 438
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
2-263 7.83e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.90  E-value: 7.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646   2 SPQAKLISIM-SLTLGTTITISSNHWMMAWTGLEinTLAILP-LIS--KPHHPRAIEATTKYFLVQAAASTLLLF-SSMT 76
Cdd:PRK02504  107 TPLGEFAAILlTATLGGMFLSGATELVMIFISLE--TLSIASyLLTgyMKRDPRSNEAALKYLLIGAASSAIFLYgSSLL 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  77 NAWFTGQwdiTQL--------THPTSCLLLT-----AAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLL 143
Cdd:PRK02504  185 YGLSGGS---TQLsaialaliTSPSLGLALAlvfviAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAI 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 144 LTSHSLNP-------ILLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPK--LTLLTFYL--YCLM- 211
Cdd:PRK02504  262 RLLVTAFPsfdeqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTEagYASMVFYLlaYLFMn 341

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1917171646 212 ----TAAIFFTLNTTKAlKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK02504  342 lgafACVILFSLRTGTD-QISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-313 1.52e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 52.79  E-value: 1.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  33 LEINTLAILPLIS-KPHHPRAIEATTKYFLVQAAASTLLLFS---------SMTNAWFTGQWDITQLTHPTSCL-LLTAA 101
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENPTVVAKIALaLFIAG 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 102 ISMKLGLAPFHFWFPEVLQG--SSLTTGLLLATA------MKLPPITLLLLTSHSLNPILLTLMAITSAALGGWAGLNQT 173
Cdd:PRK08376  230 LAMKSGAVPVHMWLPDAYPAapSSISAMLLVIKQaglyalARVLFSIYGPAINLATVGWVIIILGCLTMFVGVAMAVVQK 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 174 QIRKILAFSSISHLGWMAV-----ILTYNPklTLLTFYLYCLMTAAIFFTLNTT--KAL---------------KLSTMM 231
Cdd:PRK08376  310 DVKRLLAYHSVSQIGYMLLglgvgLAALGD--PAMASYGEIALAGGIYHIVNHAlyKALlfltagaviyetgtrNLNELG 387

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 232 TAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQelTKQEMTPTATIIALL-SLLGLFFYLRLAYcaTITLPPNSVN 310
Cdd:PRK08376  388 GLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYE--SSALFNPILGVIAMIgSVLTLASFVKVFH--TAFFGPPSEK 463


                  ...
gi 1917171646 311 YMK 313
Cdd:PRK08376  464 VMN 466
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-298 4.79e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 48.07  E-value: 4.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  34 EINTLAILPLISKPHHpRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDIT-------QLTHPTSC----LLLTAAI 102
Cdd:PRK08668  128 EIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFAdisqgliNDTSTGFAlivfLFLLAFG 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 103 SMKLGLAPFHFWFPE-----------VLQGSSLTTG-----LLLATAM--KLPPITLLLLTSHSLNPILLTLMAITsAAL 164
Cdd:PRK08668  207 VAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLGaygflLVLYVLPgtKLFSEFGTYRGVPLFNYILAWLGNIS-IIV 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 165 GGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLT----LLTFYLYCLMTAAIFFTLNT----TKALKLSTMMTAWTK 236
Cdd:PRK08668  286 GTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGfaggLFHVFNHALFKGLFFLIFAAviyrTGTTKISEMGGLIEK 365

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1917171646 237 IPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLSLLGLFFYLRLAY 298
Cdd:PRK08668  366 MPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 92-271 1.47e-05

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 46.88  E-value: 1.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  92 PTSCLLLTAAI--SMKLGLapfHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT-----SAAL 164
Cdd:MTH00032  226 IIGILLLIGCIgkSAQLGL---HTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPLFEKAPLTLLIITifgalTAFF 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 165 GGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYL--YCLMTAAIFFTLN------TTKALKLSTMMTAWTK 236
Cdd:MTH00032  303 AATVGLVQNDLKKVIAYSTCSQLGYMVLIIGIEGSHNVGLFHLvnHAFFKALLFLSAGsvihstTVDEQDMRKMGGLIHS 382

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1917171646 237 IPSLTATLMLTLLSLAGLPPLTGFLPKWLIIqELT 271
Cdd:MTH00032  383 IPFTYTMMLIGSFSIMGLPYLTGFYSKDLIL-ELT 416
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-188 1.81e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 46.23  E-value: 1.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  49 HPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQW--DITQLTH---PTS-----CLLLTAAISMKLGLAPFHFWFPEV 118
Cdd:COG1008   156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplPLTaqlllFLAFFIAFAVKVPMFPFHTWLPDA 235

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1917171646 119 LQGSSLTTGLLLATAMKLP--------PITLLLLTSHSLNPILLTLmAITSAALGGWAGLNQTQIRKILAFSSISHLG 188
Cdd:COG1008   236 HVEAPTAGSVLLAGVLLKMggygllrfALPLFPEASAYFAPLLAAL-GVIGIIYGALVALAQTDLKRLIAYSSVSHMG 312
PRK12650 PRK12650
DUF4040 family protein;
98-304 2.99e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 45.80  E-value: 2.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  98 LTAAISMKLGLA--------PFHFWFPEVLQGSSLTTGLLLATAM-KLPPITLLLLTSHSLN----PILLTLMAITSAAL 164
Cdd:PRK12650  206 LTTVVAVLIAVAaftksaqfPFHFWLPEAMAAITPVSAFLHAAAVvKAGIYLLLRFSPVFHDvavwNWLLIIVGMITALM 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 165 GGWAGLNQTQIRKILAFSSISHLGWM-AVILTYNPkltlltfylyCLMTAAIFFTLntTKAL-KLSTMMTA--------- 233
Cdd:PRK12650  286 GAVFAVQKTDLKKLTAYSTVSQLGWIvATIGVGTP----------FALTAAVVHTL--AHALfKSSLFMLIgvvdhqagt 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 234 ---------WTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMtPTATIIALLSLLGLFFYLRLAYCATITL 304
Cdd:PRK12650  354 rdirrlgslWRRMPFTFVSVTIAALSMAAVPPLFGFVSKEGMLTAFLEAPG-GNAGVVLLLVGAALGAVFTFAYSARLVL 432
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 151-298 3.12e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 45.53  E-value: 3.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 151 PILLTLMAITSAA---LGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNpkltlltfylycLMTAAIFFTLN--TTKAL 225
Cdd:COG1009   272 PVWLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG------------AYVAALFHLLThaFFKAL 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 226 ------------------KLSTMmtaWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQE-LTKQEMTPTATIIALL- 285
Cdd:COG1009   340 lflgagsvihatgtrdirKMGGL---RKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAaLEAGGLGPLLLAVALLg 416

                         170
                  ....*....|...
gi 1917171646 286 SLLGLFFYLRLAY 298
Cdd:COG1009   417 AFLTAFYSFRLFF 429
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-288 3.71e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 45.32  E-value: 3.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  50 PRAIEATTKYFLVQAAASTLLLFSSMTNAWFTG------QWDITQLTHPTSCLLLTA---AISMKLGLAPFHFWFPEV-- 118
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGgtfdllELLNLPLPFGVQTWLFLAffiAFAVKVPLFPLHTWLPDAhv 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 119 ---LQGSSLTTGLLLATA---MKLPPITLLLLTSHSLNPILLTLmAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAV 192
Cdd:TIGR01972 232 eapTAGSVILAGVLLKMGtygFLRFNLPLFPDASLYFAPVLAAL-GVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 193 -ILTYNPKLT---LLTFYLYCLMTAAIFFTLNT----TKALKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKW 264
Cdd:TIGR01972 311 gIFSFNELGIsgaVFQMISHGLITAALFLLVGVlyerAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEF 390

                         250       260
                  ....*....|....*....|....
gi 1917171646 265 LIIQELTKqeMTPTATIIALLSLL 288
Cdd:TIGR01972 391 LILLGSFK--VNPVVAFLAALGIV 412
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-290 9.40e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 40.79  E-value: 9.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  55 ATTKYFLVQAAASTLLLFSSMTNAWFTGQ--WDITQLTH---PTSC-LLLTA----AISMKLGLAPFHFWFPEV-----L 119
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAksyPLALeLLLYAgfliAFGVKLPIFPLHTWLPDAhgeasA 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 120 QGSSLTTGLLL---ATAMKLPPITLLLLTSHSLNPILLTLmAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAV-ILT 195
Cdd:PRK12561  218 PVSMILAGVLLkmgGYALIRFNVQMLPDAHVYFAPALAIL-GVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLgIAA 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 196 YNP---KLTLLTFYLYCLMTAAIFF----TLNTTKALKLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK12561  297 FTDlgiSGAMLQMISHGLIAAALFFltgvTYERTHTLSIPNMGGLAKVMPKTFALFTASSMASLALPGMSGFVSELTVFL 376

                         250       260
                  ....*....|....*....|....
gi 1917171646 269 ELTKQEM--TPTATIIALLSLLGL 290
Cdd:PRK12561  377 GITSSDVysSTFRTITILLAAVGL 400
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-271 1.07e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 40.71  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  33 LEINTLAILPLISKPHHPRAIEATTKYFLVQAAASTLLLFSSMTNAWFTGQWDITQLTH--PTSCLLLTAAISMKLGLAP 110
Cdd:PRK07234  123 LEVLSIATFLLVAYPRTDRAIWVGLRYLFYSNVAMLFYLIGAVLVYQANGTFAFSGLATadPEAFALIALGLLVKGGIFV 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 111 FHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPI--LLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLG 188
Cdd:PRK07234  203 SGLWLPLTHSEAEPPVSALLSGVVVKAGVFPLVRCALDVPGLdlIVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQLG 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 189 WMAVILTYNPKLTLltfyLYCLMTAAIFFTLN-----TTKALKlSTMMTAWTKIPsltatLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK07234  283 FILAAPLVGGLYAL----AHGLVKSTLFLCAGalpsrNFTELI-SQMLGIGKWIP-----LTMASFSIAGFPLLAGFVSK 352


                  ....*...
gi 1917171646 264 WLIIQELT 271
Cdd:PRK07234  353 VLTLKNLL 360
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 96-284 1.31e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 40.68  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  96 LLLTAAISmKLGLAPFHFWFPEVLQGSSLTTGLLLATAMK------LPPITLLLLTSHSLNPILLTLMAITsAALGGWAG 169
Cdd:PRK12644  208 LILVGALS-KSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVkagiylVARLAPGFADVPVWRPTVLVLGLAT-MLLGGWRA 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 170 LNQTQIRKILAFSSISHLGWMAVIL---TYNPKLTLLTFYL-YCLMTAAIFFTLNT------TKAL-KLSTMmtaWTKIP 238
Cdd:PRK12644  286 LRQHDLKLILAYGTVSQLGFLTVLVgigTRDAALAGLAMLLaHALFKAALFLVVGIidhstgTRDIrKLSGL---GRRQP 362

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1917171646 239 SLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIAL 284
Cdd:PRK12644  363 VLAVVAALAAASMAGLPPLLGFVAKEAALEAVLHDGALGPAGPVVL 408
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-190 1.46e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 40.12  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  13 LTLGTTITISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLVQAAA------STLLLFSSMTNAWFTGQWDI 86
Cdd:PRK08676  111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  87 TQLTHPTSCL---LLTAAISM-------KLGLAPFHFWFPEVLQG-----SSLTTGLLLATAM----KLPPITLLLLTSH 147
Cdd:PRK08676  191 TELAAHASLLspsVLGASFLFifigflaKSGLVPFHTWLPAAYAKapsvvSALLSGTVLNIGIygilRLSALLRQSGAAE 270

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1917171646 148 SLNPILLTLmAITSAALGGWAGLNQTQIRKILAFSSISHLGWM 190
Cdd:PRK08676  271 QFSNVLIGL-GIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLM 312
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-218 2.10e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 39.91  E-value: 2.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  20 TISSNHWMMAWTGLEINTLAILPLISKPHHPRAIEATTKYFLV------QAAASTLLLFSSMTnawftgqwdiTQLTHPT 93
Cdd:PRK06458  124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIIcsvgvaFALFGTILVYANAA----------TVMGDGE 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  94 SCLLLTAAISM----------------------KLGLAPFHFWFPEVLQG-----SSLTTGLLLATAMKLPPITLLLLTS 146
Cdd:PRK06458  194 MAILWTELLKHaslldptlmklafvflligfgtKVGLFPMHAWLPDAHSEapspvSALLSGVLLNVALYAVLRYYILIDA 273

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1917171646 147 HSLN---PILLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTLLTFYLYCLM----TAAIFFT 218
Cdd:PRK06458  274 AIGSdfpGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNhsltKSAIFFA 352
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 95-298 3.16e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 39.29  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646  95 CLLLTAAISMKLGLAPFHFWFPEVLQGSSLTTGLLLATAMKLPPITLLLLTSHSLNPILLTLMAIT-----SAALGGWAG 169
Cdd:MTH00020  213 CLFLFIGAVGKSAQLGLHTWLPDAMEGPTPVSALIHAATMVTAGVFLLIRSSPLFEQAPLALIIVTivgslTVFFAATVG 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 170 LNQTQIRKILAFSSISHLGWMAVILTynpkltlLTFY---LYCLMTAAIFFTL------NTTKAL----KLSTMMTAWTK 236
Cdd:MTH00020  293 LVQNDLKKVIAYSTCSQLGYMVVACG-------LSHYsisLFHLMNHAFFKALlflsagSVIHALsdeqDMRKMGGLISF 365

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1917171646 237 IPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTPTATIIALLS-LLGLFFYLRLAY 298
Cdd:MTH00020  366 LPLTYIFFLIGSLSLMGFPYLTGFYSKDLILELAFGQYYLIFAYWLGCFSaLLTAFYSIRLIY 428
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-322 6.73e-03

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 34.16  E-value: 6.73e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1917171646 291 FFYLRLAYCATITLPPNSVNYMKLWQTNKPVN 322
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKN 32
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
153-298 8.42e-03

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 38.01  E-value: 8.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917171646 153 LLTLMAITSAALGGWAGLNQTQIRKILAFSSISHLGWMAVILTYNPKLTL--LTFYLYCLMT--AAIFFTLNTTKAL--- 225
Cdd:PRK12663  274 LLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGIngAIFYLVHDMVvkTALFLIAGSLVRLtgy 353

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1917171646 226 -KLSTMMTAWTKIPSLTATLMLTLLSLAGLPPLTGFLPKWLIIQ-ELTKQEMTPTATIIA--LLSLLGLFFYLRLAY 298
Cdd:PRK12663  354 rSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQgALDNGAYILLALMLItsLITMYSLFRIFFLAY 430
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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