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Conserved domains on  [gi|2047724717|gb|QWC87075|]
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MSMEG_0569 family flavin-dependent oxidoreductase [Nocardioidaceae bacterium]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MSMEG_0569_nitr super family cl40808
flavin-dependent oxidoreductase, MSMEG_0569 family; Members of this protein family belong to a ...
 21-417 0e+00

flavin-dependent oxidoreductase, MSMEG_0569 family; Members of this protein family belong to a conserved seven-gene biosynthetic cluster found sparsely in Cyanobacteria, Proteobacteria, and Actinobacteria. Distant homologies to characterized proteins suggest that members are enzymes dependent on a flavinoid cofactor.


The actual alignment was detected with superfamily member TIGR04046:

Pssm-ID: 274942  Cd Length: 400  Bit Score: 644.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  21 QAGLSTSWHLTDQGIDHVVLEARTAGHEWADRRWDAFTLVTPNWHCRLPGYAYDGPDPDGFMTRDEVVAWLGGYAATFDP 100
Cdd:TIGR04046  10 QAGLSVSYYLKQAGIDHVVLEKHTVAHSWRDERWDSFCLVTPNWQCRLPGHPYDGTDPDGFMVKDEIVAYLDGYARSFNP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 101 PLVEHTAARSLVRTD-DGYEVAvvgpDGPETWRADQVVIATGGYHQPIVPAWAPALDPAITQLHSADYLEPDQLPDGGVL 179
Cdd:TIGR04046  90 PVREGTEVTSLRKHGaGGFRVS----TSAGAFTADQVVIATGGYHVPVIPPLAERLPADVLQLHSSEYRNPDQLPDGAVL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 180 VVGTGQSGTQIAEDLHLAGRQVHLALGDAPRVARTYRGRDSMTWLADMGVYDKPVETLTPMAASQEKTNHYVTGRDGGRD 259
Cdd:TIGR04046 166 VVGSGQSGCQIAEDLHLAGRKVHLAVGSAPRCARFYRGRDVVDWLDDMGYYDLPVDEHPDPESVRDKTNHYVTGRDGGRD 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 260 IDLREFAAQGMRLYGLLDDLAEtgtARLRFRATLAQSLDHADAVYNSICGDIDRWIDAQGIDAPPATRYEPVWRPEEEPT 339
Cdd:TIGR04046 246 IDLRRFALEGMQLYGRLEDIRE---GQLRFAPDLKANLDGADAVYNRINASIDAYIAKNGIEAPPESPYQPVWEPEEEPT 322

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2047724717 340 ALDLHEAGITSVVWAIGYRPDYRWVGCDVFDGAGRPVHHRGETSVPGLYFLGLPWLHTWGSGRFLGIADDAAHVVGRI 417
Cdd:TIGR04046 323 ELDLAAAGITSVIWCTGFRPDYSWVDLPVFDGAGYPVHDRGVTAVPGLYFLGLPWLHTWGSGRFSGIARDAAYLADQI 400
 
Name Accession Description Interval E-value
MSMEG_0569_nitr TIGR04046
flavin-dependent oxidoreductase, MSMEG_0569 family; Members of this protein family belong to a ...
 21-417 0e+00

flavin-dependent oxidoreductase, MSMEG_0569 family; Members of this protein family belong to a conserved seven-gene biosynthetic cluster found sparsely in Cyanobacteria, Proteobacteria, and Actinobacteria. Distant homologies to characterized proteins suggest that members are enzymes dependent on a flavinoid cofactor.


Pssm-ID: 274942  Cd Length: 400  Bit Score: 644.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  21 QAGLSTSWHLTDQGIDHVVLEARTAGHEWADRRWDAFTLVTPNWHCRLPGYAYDGPDPDGFMTRDEVVAWLGGYAATFDP 100
Cdd:TIGR04046  10 QAGLSVSYYLKQAGIDHVVLEKHTVAHSWRDERWDSFCLVTPNWQCRLPGHPYDGTDPDGFMVKDEIVAYLDGYARSFNP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 101 PLVEHTAARSLVRTD-DGYEVAvvgpDGPETWRADQVVIATGGYHQPIVPAWAPALDPAITQLHSADYLEPDQLPDGGVL 179
Cdd:TIGR04046  90 PVREGTEVTSLRKHGaGGFRVS----TSAGAFTADQVVIATGGYHVPVIPPLAERLPADVLQLHSSEYRNPDQLPDGAVL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 180 VVGTGQSGTQIAEDLHLAGRQVHLALGDAPRVARTYRGRDSMTWLADMGVYDKPVETLTPMAASQEKTNHYVTGRDGGRD 259
Cdd:TIGR04046 166 VVGSGQSGCQIAEDLHLAGRKVHLAVGSAPRCARFYRGRDVVDWLDDMGYYDLPVDEHPDPESVRDKTNHYVTGRDGGRD 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 260 IDLREFAAQGMRLYGLLDDLAEtgtARLRFRATLAQSLDHADAVYNSICGDIDRWIDAQGIDAPPATRYEPVWRPEEEPT 339
Cdd:TIGR04046 246 IDLRRFALEGMQLYGRLEDIRE---GQLRFAPDLKANLDGADAVYNRINASIDAYIAKNGIEAPPESPYQPVWEPEEEPT 322

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2047724717 340 ALDLHEAGITSVVWAIGYRPDYRWVGCDVFDGAGRPVHHRGETSVPGLYFLGLPWLHTWGSGRFLGIADDAAHVVGRI 417
Cdd:TIGR04046 323 ELDLAAAGITSVIWCTGFRPDYSWVDLPVFDGAGYPVHDRGVTAVPGLYFLGLPWLHTWGSGRFSGIARDAAYLADQI 400
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 21-421 7.25e-73

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 234.76  E-value: 7.25e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  21 QAGLSTSWHLTDQGIDHVVLEARTA-GHEWADRRWDAFTLVTPNWHCRLPGYAYDGPDPDgFMTRDEVVAWLGGYAATFD 99
Cdd:COG2072    16 QAGLAAAYHLRRAGIDFVVLEKADDvGGTWRDNRYPGLRLDTPSHLYSLPFFPNWSDDPD-FPTGDEILAYLEAYADKFG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 100 --PPLVEHTAARSLV--RTDDGYEVAVvgpDGPETWRADQVVIATGGYHQPIVPAWAPALDPAITQLHSADYLEPDQLPD 175
Cdd:COG2072    95 lrRPIRFGTEVTSARwdEADGRWTVTT---DDGETLTARFVVVATGPLSRPKIPDIPGLEDFAGEQLHSADWRNPVDLAG 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 176 GGVLVVGTGQSGTQIAEDLHLAGRQVHLALGDAPRVA-----RTYRGRDSMTWLADMGVydkpvetltpmaasqektnhy 250
Cdd:COG2072   172 KRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLprpnyDPERGRPANYLGLEAPP--------------------- 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 251 vtgrdGGRDIDLREFAAQGMRL------YGLLDDLAETGTARL----RFRATLAQslDHADAVynsiCGDIDRwIDAQGI 320
Cdd:COG2072   231 -----ALNRRDARAWLRRLLRAqvkdpeLGLLTPDYPPGCKRPllstDYYEALRR--GNVELV----TGGIER-ITEDGV 298

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 321 dappatryepVWRpeeeptalDLHEAGITSVVWAIGYRPDYRWV-GCDVFDGAGR--PVHHRGETS--VPGLYFLGLPWL 395
Cdd:COG2072   299 ----------VFA--------DGTEHEVDVIVWATGFRADLPWLaPLDVRGRDGRsgPRAYLGVVVpgFPNLFFLGPNSP 360

                         410       420
                  ....*....|....*....|....*.
gi 2047724717 396 HTWgSGRFLGIADDAAHVVGRIRDRR 421
Cdd:COG2072   361 SGH-SSLTLGAERQARYIARLIAHMR 385
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
22-216 2.55e-11

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 64.17  E-value: 2.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  22 AGLSTSWHLTDQGI-DHVVLEARTAGHEWadRRWDA-FTLVTPNWHC--------------RLPGYAYDGPDPdgfmTRD 85
Cdd:pfam13738   2 AGIGCAIALKKAGLeDYLILEKGNIGNSF--YRYPThMTFFSPSFTSngfgipdlnaispgTSPAFTFNREHP----SGN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  86 EVVAWLGGYAATFDPPLVEHTAARSLVRTDDGYEVAVVGpdgpETWRADQVVIATGGYHQPIVPawapalDPAITQLHSA 165
Cdd:pfam13738  76 EYAEYLRRVADHFELPINLFEEVTSVKKEDDGFVVTTSK----GTYQARYVIIATGEFDFPNKL------GVPELPKHYS 145

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2047724717 166 DYLEPDQLPDGGVLVVGTGQSGTQIAEDLHLAGRQVHLALGDAPRVARTYR 216
Cdd:pfam13738 146 YVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGSEWEDRDSD 196
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 77-204 1.06e-04

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 44.47  E-value: 1.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  77 DPDGFMTRDEVVAWLGGYAATFDppLVEhtaarsLVRTDDgyEVAVVGP-DGpeTWRA--------------DQVVIATG 141
Cdd:PLN02172  103 DSRRYPSHREVLAYLQDFAREFK--IEE------MVRFET--EVVRVEPvDG--KWRVqsknsggfskdeifDAVVVCNG 170

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2047724717 142 GYHQPIVpAWAPALD--PAiTQLHSADYLEPDQLPDGGVLVVGTGQSGTQIAEDLHLAGRQVHLA 204
Cdd:PLN02172  171 HYTEPNV-AHIPGIKswPG-KQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIA 233
 
Name Accession Description Interval E-value
MSMEG_0569_nitr TIGR04046
flavin-dependent oxidoreductase, MSMEG_0569 family; Members of this protein family belong to a ...
 21-417 0e+00

flavin-dependent oxidoreductase, MSMEG_0569 family; Members of this protein family belong to a conserved seven-gene biosynthetic cluster found sparsely in Cyanobacteria, Proteobacteria, and Actinobacteria. Distant homologies to characterized proteins suggest that members are enzymes dependent on a flavinoid cofactor.


Pssm-ID: 274942  Cd Length: 400  Bit Score: 644.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  21 QAGLSTSWHLTDQGIDHVVLEARTAGHEWADRRWDAFTLVTPNWHCRLPGYAYDGPDPDGFMTRDEVVAWLGGYAATFDP 100
Cdd:TIGR04046  10 QAGLSVSYYLKQAGIDHVVLEKHTVAHSWRDERWDSFCLVTPNWQCRLPGHPYDGTDPDGFMVKDEIVAYLDGYARSFNP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 101 PLVEHTAARSLVRTD-DGYEVAvvgpDGPETWRADQVVIATGGYHQPIVPAWAPALDPAITQLHSADYLEPDQLPDGGVL 179
Cdd:TIGR04046  90 PVREGTEVTSLRKHGaGGFRVS----TSAGAFTADQVVIATGGYHVPVIPPLAERLPADVLQLHSSEYRNPDQLPDGAVL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 180 VVGTGQSGTQIAEDLHLAGRQVHLALGDAPRVARTYRGRDSMTWLADMGVYDKPVETLTPMAASQEKTNHYVTGRDGGRD 259
Cdd:TIGR04046 166 VVGSGQSGCQIAEDLHLAGRKVHLAVGSAPRCARFYRGRDVVDWLDDMGYYDLPVDEHPDPESVRDKTNHYVTGRDGGRD 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 260 IDLREFAAQGMRLYGLLDDLAEtgtARLRFRATLAQSLDHADAVYNSICGDIDRWIDAQGIDAPPATRYEPVWRPEEEPT 339
Cdd:TIGR04046 246 IDLRRFALEGMQLYGRLEDIRE---GQLRFAPDLKANLDGADAVYNRINASIDAYIAKNGIEAPPESPYQPVWEPEEEPT 322

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2047724717 340 ALDLHEAGITSVVWAIGYRPDYRWVGCDVFDGAGRPVHHRGETSVPGLYFLGLPWLHTWGSGRFLGIADDAAHVVGRI 417
Cdd:TIGR04046 323 ELDLAAAGITSVIWCTGFRPDYSWVDLPVFDGAGYPVHDRGVTAVPGLYFLGLPWLHTWGSGRFSGIARDAAYLADQI 400
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 21-421 7.25e-73

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 234.76  E-value: 7.25e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  21 QAGLSTSWHLTDQGIDHVVLEARTA-GHEWADRRWDAFTLVTPNWHCRLPGYAYDGPDPDgFMTRDEVVAWLGGYAATFD 99
Cdd:COG2072    16 QAGLAAAYHLRRAGIDFVVLEKADDvGGTWRDNRYPGLRLDTPSHLYSLPFFPNWSDDPD-FPTGDEILAYLEAYADKFG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 100 --PPLVEHTAARSLV--RTDDGYEVAVvgpDGPETWRADQVVIATGGYHQPIVPAWAPALDPAITQLHSADYLEPDQLPD 175
Cdd:COG2072    95 lrRPIRFGTEVTSARwdEADGRWTVTT---DDGETLTARFVVVATGPLSRPKIPDIPGLEDFAGEQLHSADWRNPVDLAG 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 176 GGVLVVGTGQSGTQIAEDLHLAGRQVHLALGDAPRVA-----RTYRGRDSMTWLADMGVydkpvetltpmaasqektnhy 250
Cdd:COG2072   172 KRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLprpnyDPERGRPANYLGLEAPP--------------------- 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 251 vtgrdGGRDIDLREFAAQGMRL------YGLLDDLAETGTARL----RFRATLAQslDHADAVynsiCGDIDRwIDAQGI 320
Cdd:COG2072   231 -----ALNRRDARAWLRRLLRAqvkdpeLGLLTPDYPPGCKRPllstDYYEALRR--GNVELV----TGGIER-ITEDGV 298

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 321 dappatryepVWRpeeeptalDLHEAGITSVVWAIGYRPDYRWV-GCDVFDGAGR--PVHHRGETS--VPGLYFLGLPWL 395
Cdd:COG2072   299 ----------VFA--------DGTEHEVDVIVWATGFRADLPWLaPLDVRGRDGRsgPRAYLGVVVpgFPNLFFLGPNSP 360

                         410       420
                  ....*....|....*....|....*.
gi 2047724717 396 HTWgSGRFLGIADDAAHVVGRIRDRR 421
Cdd:COG2072   361 SGH-SSLTLGAERQARYIARLIAHMR 385
IucD COG3486
Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism] ...
 112-195 3.16e-12

Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442709 [Multi-domain]  Cd Length: 440  Bit Score: 67.89  E-value: 3.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 112 VRTDDGYEVAVVGPDG-PETWRADQVVIATGgyHQPIVPAWAPALDPAiTQLHSADYLE-PDQLPDGG-VLVVGTGQSGT 188
Cdd:COG3486   127 DDDAGAFRVTVRDGTGeRETYRARNLVLGTG--TRPYLPECFRGLPGE-RVFHSSEYLHrKEDLQAAKrVTVVGSGQSAA 203


                  ....*..
gi 2047724717 189 QIAEDLH 195
Cdd:COG3486   204 EIFLDLL 210
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
22-216 2.55e-11

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 64.17  E-value: 2.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  22 AGLSTSWHLTDQGI-DHVVLEARTAGHEWadRRWDA-FTLVTPNWHC--------------RLPGYAYDGPDPdgfmTRD 85
Cdd:pfam13738   2 AGIGCAIALKKAGLeDYLILEKGNIGNSF--YRYPThMTFFSPSFTSngfgipdlnaispgTSPAFTFNREHP----SGN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  86 EVVAWLGGYAATFDPPLVEHTAARSLVRTDDGYEVAVVGpdgpETWRADQVVIATGGYHQPIVPawapalDPAITQLHSA 165
Cdd:pfam13738  76 EYAEYLRRVADHFELPINLFEEVTSVKKEDDGFVVTTSK----GTYQARYVIIATGEFDFPNKL------GVPELPKHYS 145

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2047724717 166 DYLEPDQLPDGGVLVVGTGQSGTQIAEDLHLAGRQVHLALGDAPRVARTYR 216
Cdd:pfam13738 146 YVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGSEWEDRDSD 196
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 118-195 4.51e-11

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 63.76  E-value: 4.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 118 YEVAVVGPDG-PETWRADQVVIATGGyhQPIVPAWAPALDPAItqlHSADYLE--PDQLPDGGVLVVGTGQSGTQIAEDL 194
Cdd:pfam13434 132 LRVRVRDADGeETTFLARNLVLGTGG--EPYIPECARGGERVF---HSSEYLEriDRLAAKKRIAVVGSGQSAAEIFRDL 206


                  .
gi 2047724717 195 H 195
Cdd:pfam13434 207 L 207
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 77-204 1.06e-04

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 44.47  E-value: 1.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  77 DPDGFMTRDEVVAWLGGYAATFDppLVEhtaarsLVRTDDgyEVAVVGP-DGpeTWRA--------------DQVVIATG 141
Cdd:PLN02172  103 DSRRYPSHREVLAYLQDFAREFK--IEE------MVRFET--EVVRVEPvDG--KWRVqsknsggfskdeifDAVVVCNG 170

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2047724717 142 GYHQPIVpAWAPALD--PAiTQLHSADYLEPDQLPDGGVLVVGTGQSGTQIAEDLHLAGRQVHLA 204
Cdd:PLN02172  171 HYTEPNV-AHIPGIKswPG-KQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIA 233
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
102-216 1.41e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 43.74  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 102 LVEHTAARSLVRTDDGYeVAVVGPDGpeTWRADQVVIATGGYHQPIVPAWAPALdPAITQLHSADYLEPDQLPDGGVLVV 181
Cdd:COG0665   168 IREGTPVTGLEREGGRV-TGVRTERG--TVRADAVVLAAGAWSARLLPMLGLRL-PLRPVRGYVLVTEPLPDLPLRPVLD 243

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2047724717 182 GTGQSGTQIAEDLHLAGRQVHLALGDAPRVARTYR 216
Cdd:COG0665   244 DTGVYLRPTADGRLLVGGTAEPAGFDRAPTPERLE 278
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
95-203 6.14e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 41.64  E-value: 6.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  95 AATFDPPLVEHTAaRSLVRTDDGYEVAVvgpDGPETWRADQVVIATGGYHQPI-VPAWAPALDpaiTQLHSADYLEPDQL 173
Cdd:COG0492    67 AERFGAEILLEEV-TSVDKDDGPFRVTT---DDGTEYEAKAVIIATGAGPRKLgLPGEEEFEG---RGVSYCATCDGFFF 139

                          90       100       110
                  ....*....|....*....|....*....|
gi 2047724717 174 PDGGVLVVGTGQSGTQIAEDLHLAGRQVHL 203
Cdd:COG0492   140 RGKDVVVVGGGDSALEEALYLTKFASKVTL 169
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 74-204 7.19e-04

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 41.69  E-value: 7.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  74 DGPDPD---GFMTRDEVVAWLGGYAATFDppLVEHTAARSLV---------RTDDGYEVAVVGPDGPETWRADQVVIATG 141
Cdd:pfam00743  70 DFPFPEdypNFMHNSKFLEYFRMFAKEFD--LLKYIQFKTTVcsvkkrpdfSTSGQWEVVTEHEGKQESAVFDAVMVCTG 147

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2047724717 142 GYHQPIVPAWA-PALDPAITQ-LHSADYLEPDQLPDGGVLVVGTGQSGTQIAEDLHLAGRQVHLA 204
Cdd:pfam00743 148 HHTNPHLPLESfPGIEKFKGQyFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLS 212
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 81-203 9.27e-04

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 40.95  E-value: 9.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  81 FMTRDEVVAwlggyaatFDPplvehtaARSLVRTDDGyevavvgpdgpETWRADQVVIATGGyhQPIVPAWAPALDPAIT 160
Cdd:COG0446    53 VRTGTEVTA--------IDP-------EAKTVTLRDG-----------ETLSYDKLVLATGA--RPRPPPIPGLDLPGVF 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2047724717 161 QLHSADYLEP--DQLPDGG---VLVVGTGQSGTQIAEDLHLAGRQVHL 203
Cdd:COG0446   105 TLRTLDDADAlrEALKEFKgkrAVVIGGGPIGLELAEALRKRGLKVTL 152
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 54-442 2.26e-03

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 40.63  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717   54 WDAFTLVTPNWHCRLPGYAYDGPDPDGFMTRDEVVAWLGGYAATFDPPLVEHTAARSLVRTDDGYEVAVVGPDGPETWRA 133
Cdd:COG3321    849 WSALYPGRGRRRVPLPTYPFQREDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAA 928

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  134 DQVVIATGGYHQPIVPAWAPALDPAITQLH----------SADYLEPDQLPDGGVLVVGTGQSGTQIAEDLHLAGRQVHL 203
Cdd:COG3321    929 LLALVALAAAAAALLALAAAAAAAAAALAAaeagallllaAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAA 1008

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  204 ALGDAPRVARTYRGRDSMTWLADMGVYDKPVETLTPMAASQEKTNHYVTGRDGGRDIDLREFAAQGMRLYGLLDDLAETG 283
Cdd:COG3321   1009 ALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAA 1088

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  284 TARLRFRATLAQSLDHADAVYNSICGDIDRWIDAQGIDAPPATRYEPVWRPEEEPTALDLHEAGITSVVWAIGYRPDYRW 363
Cdd:COG3321   1089 ALAAAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALL 1168

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2047724717  364 VGCDVFDGAGRPVHHRGETSVPGLYFLGLPWLHTWGSGRFLGIADDAAHVVGRIRDRRMGLGPARRGSATSVLDVAVAG 442
Cdd:COG3321   1169 AAAALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAA 1247
PRK06116 PRK06116
glutathione reductase; Validated
 129-209 3.13e-03

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 39.75  E-value: 3.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 129 ETWRADQVVIATGGYhqPIVPAwAPALDPAITqlhSADYLEPDQLPDgGVLVVGTGQSGTQIAEDLHLAGRQVHLAL-GD 207
Cdd:PRK06116  128 ERYTADHILIATGGR--PSIPD-IPGAEYGIT---SDGFFALEELPK-RVAVVGAGYIAVEFAGVLNGLGSETHLFVrGD 200


                  ..
gi 2047724717 208 AP 209
Cdd:PRK06116  201 AP 202
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
105-211 4.40e-03

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 39.35  E-value: 4.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717 105 HTAARSlVRTDDGyevavvgpdgpETWRADQVVIATGGYhqPIVPAWAPALDPAITQLHS---ADYLEpDQLPDGG-VLV 180
Cdd:COG1251    83 DRAART-VTLADG-----------ETLPYDKLVLATGSR--PRVPPIPGADLPGVFTLRTlddADALR-AALAPGKrVVV 147

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2047724717 181 VGTGQSGTQIAEDLHLAGRQVHLaLGDAPRV 211
Cdd:COG1251   148 IGGGLIGLEAAAALRKRGLEVTV-VERAPRL 177
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
63-186 4.41e-03

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 39.17  E-value: 4.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047724717  63 NWHCRLPGYAYDGPDPDGFMTRdevvAWLGGY-AATFDPPL--------VEHTAAR--SLVRTDDGYEVAVvgpDGPETW 131
Cdd:COG4529    77 RWLRENGARAAPAIDPDAFVPR----RLFGEYlRERLAEALarapagvrLRHIRAEvvDLERDDGGYRVTL---ADGETL 149

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2047724717 132 RADQVVIATGgyHQPivpawaPALDPAITQLHSADYLEP------DQLPDGG-VLVVGTGQS 186
Cdd:COG4529   150 RADAVVLATG--HPP------PAPPPGLAAGSPRYIADPwppgalARIPPDArVLIIGTGLT 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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